S100b cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	S100b
Entrez Gene ID	25742
Full Name	S100 calcium binding protein B
Synonyms	S100P
General protein information	Preferred Names S100 calcium binding protein B Names protein S100-B S-100 protein beta chain S-100 protein subunit beta S100 calcium-binding protein, beta (neural) S100 protein, beta polypeptide, neural
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 20 Map Location: 20p12
Summary	binds GTPase activating protein IQGAP1; may play a role in cell membrane rearrangement [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_013191.1	NP_037323.1	protein S100-B
XM_008772868.1	XP_008771090.1	protein S100-B isoform X1
XM_017601568.1	XP_017457057.1	protein S100-B isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	S100B	NP_006263.1
Bos taurus (cattle)	S100B	NP_001029727.1
Pan troglodytes (chimpanzee)	S100B	XP_531586.1
Canis lupus familiaris (dog)	S100B	XP_548737.3
Rattus norvegicus (Norway rat)	S100b	NP_037323.1
Gallus gallus (chicken)	S100B	XP_001233035.1
	S100B	XP_001098016.1
Mus musculus (house mouse)	S100b	NP_033141.1
Danio rerio (zebrafish)	s100b	NP_001002552.1

Gene Ontology
Bibliography

Related articles in PubMed

C6 glioma-conditioned medium induces malignant transformation of mesenchymal stem cells: Possible role of S100B/RAGE pathway.
Tan B, Shen L, Yang K, Huang D, Li X, Li Y, Zhao L, Chen J, Yi Q, Xu H, Tian J, Zhu J
Biochemical and biophysical research communications495(1)78-85(2018 Jan)

SOX10-positive cells emerge in the rat pituitary gland during late embryogenesis and start to express S100?.
Ueharu H, Yoshida S, Kanno N, Horiguchi K, Nishimura N, Kato T, Kato Y
Cell and tissue research(2017 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the RAGE pathway may play a possible role in malignant transformation of mesenchymal stem cells, and this process may be mediated through S100B
Title: C6 glioma-conditioned medium induces malignant transformation of mesenchymal stem cells: Possible role of S100B/RAGE pathway.

Maternal exposure to mercury results in increased S100B in the placenta. Zinc sulfate feeding could reduce S100B and mercury levels, thereby protecting the rats from mercury damage. S100B level may be used to measure the antagonism between zinc and mercury during pregnancy.
Title: Zinc protection in fetal rats for maternal mercury exposure-induced growth retardation is probably associated with S100B expression.

Vesicle internalization likely mitigates the toxic effects of extracellular S100B and other waste products
Title: Time-dependent uptake and trafficking of vesicles capturing extracellular S100B in cultured rat astrocytes.

These results imply that age-related AGE-albumin accumulation, S100beta, and RAGE expression are more prominent in visceral than in subcutaneous fat, suggesting that visceral fat is involved in the pathogenesis of inflammation-induced diseases in the elderly.
Title: Age-related accumulation of advanced glycation end-products-albumin, S100?, and the expressions of advanced glycation end product receptor differ in visceral and subcutaneous fat.

S100beta-positive cells of extrapituitary origin invade the anterior lobe, undergoing proliferation and diverse transformation during pituitary organogenesis.
Title: S100?-Positive Cells of Mesenchymal Origin Reside in the Anterior Lobe of the Embryonic Pituitary Gland.

The following S100b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the S100b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa12092	NM_013191.1 Latest version!	Rattus norvegicus S100 calcium binding protein B (S100b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
ORa12092	XM_017601568.1 Latest version!	Rattus norvegicus S100 calcium binding protein B (S100b), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
ORa12092	XM_008772868.1 Latest version!	Rattus norvegicus S100 calcium binding protein B (S100b), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

S100b ( NM_013191.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_037323.1 Rattus norvegicus S100 calcium binding protein B (S100b), mRNA.

Price & Availability↑

CloneID	ORa12092
Clone ID Related Accession (Same CDS sequence)	NM_013191.1 , XM_008772868.1 , XM_017601568.1
Accession Version	NM_013191.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 279bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-09
Organism	Rattus norvegicus(Norway rat)
Product	protein S100-B
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X01090.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M54919.1, X01090.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296 [ECO:0000348] ##Evidence-Data-END##

ATGTCTGAGC TGGAGAAGGC CATGGTTGCC CTCATTGATG TCTTCCATCA GTATTCAGGG 
AGAGAGGGTG ACAAGCACAA GCTGAAGAAG TCAGAACTGA AGGAGCTCAT CAACAACGAG 
CTCTCTCACT TCCTGGAGGA AATCAAAGAG CAGGAAGTGG TGGACAAAGT GATGGAGACG 
CTGGACGAAG ATGGGGATGG GGAGTGTGAC TTCCAGGAGT TTATGGCCTT CGTCTCCATG 
GTGACCACAG CCTGTCATGA GTTCTTTGAA CATGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037323.1
CDS	121..399
Translation	MSELEKAMVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDEDGDGECDFQEFMAFVSMVTTACHEFFEHE

Target ORF information:

RefSeq Version	NM_013191.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus S100 calcium binding protein B (S100b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013191.1

ORF Insert Sequence:

ATGTCTGAGC TGGAGAAGGC CATGGTTGCC CTCATTGATG TCTTCCATCA GTATTCAGGG 
AGAGAGGGTG ACAAGCACAA GCTGAAGAAG TCAGAACTGA AGGAGCTCAT CAACAACGAG 
CTCTCTCACT TCCTGGAGGA AATCAAAGAG CAGGAAGTGG TGGACAAAGT GATGGAGACG 
CTGGACGAAG ATGGGGATGG GGAGTGTGAC TTCCAGGAGT TTATGGCCTT CGTCTCCATG 
GTGACCACAG CCTGTCATGA GTTCTTTGAA CATGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

S100b ( XM_008772868.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008771090.1 Rattus norvegicus S100 calcium binding protein B (S100b), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa12092
Clone ID Related Accession (Same CDS sequence)	NM_013191.1 , XM_008772868.1 , XM_017601568.1
Accession Version	XM_008772868.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 279bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	protein S100-B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005119.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTGAGC TGGAGAAGGC CATGGTTGCC CTCATTGATG TCTTCCATCA GTATTCAGGG 
AGAGAGGGTG ACAAGCACAA GCTGAAGAAG TCAGAACTGA AGGAGCTCAT CAACAACGAG 
CTCTCTCACT TCCTGGAGGA AATCAAAGAG CAGGAAGTGG TGGACAAAGT GATGGAGACG 
CTGGACGAAG ATGGGGATGG GGAGTGTGAC TTCCAGGAGT TTATGGCCTT CGTCTCCATG 
GTGACCACAG CCTGTCATGA GTTCTTTGAA CATGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008771090.1
CDS	120..398
Translation	MSELEKAMVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDEDGDGECDFQEFMAFVSMVTTACHEFFEHE

Target ORF information:

RefSeq Version	XM_008772868.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus S100 calcium binding protein B (S100b), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008772868.1

ORF Insert Sequence:

ATGTCTGAGC TGGAGAAGGC CATGGTTGCC CTCATTGATG TCTTCCATCA GTATTCAGGG 
AGAGAGGGTG ACAAGCACAA GCTGAAGAAG TCAGAACTGA AGGAGCTCAT CAACAACGAG 
CTCTCTCACT TCCTGGAGGA AATCAAAGAG CAGGAAGTGG TGGACAAAGT GATGGAGACG 
CTGGACGAAG ATGGGGATGG GGAGTGTGAC TTCCAGGAGT TTATGGCCTT CGTCTCCATG 
GTGACCACAG CCTGTCATGA GTTCTTTGAA CATGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

S100b ( XM_017601568.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017457057.1 Rattus norvegicus S100 calcium binding protein B (S100b), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa12092
Clone ID Related Accession (Same CDS sequence)	NM_013191.1 , XM_008772868.1 , XM_017601568.1
Accession Version	XM_017601568.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 279bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	protein S100-B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005119.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTGAGC TGGAGAAGGC CATGGTTGCC CTCATTGATG TCTTCCATCA GTATTCAGGG 
AGAGAGGGTG ACAAGCACAA GCTGAAGAAG TCAGAACTGA AGGAGCTCAT CAACAACGAG 
CTCTCTCACT TCCTGGAGGA AATCAAAGAG CAGGAAGTGG TGGACAAAGT GATGGAGACG 
CTGGACGAAG ATGGGGATGG GGAGTGTGAC TTCCAGGAGT TTATGGCCTT CGTCTCCATG 
GTGACCACAG CCTGTCATGA GTTCTTTGAA CATGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017457057.1
CDS	176..454
Translation	MSELEKAMVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDEDGDGECDFQEFMAFVSMVTTACHEFFEHE

Target ORF information:

RefSeq Version	XM_017601568.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus S100 calcium binding protein B (S100b), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017601568.1

ORF Insert Sequence:

ATGTCTGAGC TGGAGAAGGC CATGGTTGCC CTCATTGATG TCTTCCATCA GTATTCAGGG 
AGAGAGGGTG ACAAGCACAA GCTGAAGAAG TCAGAACTGA AGGAGCTCAT CAACAACGAG 
CTCTCTCACT TCCTGGAGGA AATCAAAGAG CAGGAAGTGG TGGACAAAGT GATGGAGACG 
CTGGACGAAG ATGGGGATGG GGAGTGTGAC TTCCAGGAGT TTATGGCCTT CGTCTCCATG 
GTGACCACAG CCTGTCATGA GTTCTTTGAA CATGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

C6 glioma-conditioned medium induces malignant transformation of mesenchymal stem cells: Possible role of S100B/RAGE pathway.
Biochemical and biophysical research communications495(1)78-85(2018 Jan)
Tan B,Shen L,Yang K,Huang D,Li X,Li Y,Zhao L,Chen J,Yi Q,Xu H,Tian J,Zhu J

SOX10-positive cells emerge in the rat pituitary gland during late embryogenesis and start to express S100?.
Cell and tissue research(2017 Nov)
Ueharu H,Yoshida S,Kanno N,Horiguchi K,Nishimura N,Kato T,Kato Y

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S100b cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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Services & Products

見積依頼

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電話

FAX

オンラインフォーム