Il6st cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Il6st
Entrez Gene ID	25205
Full Name	interleukin 6 signal transducer
Synonyms	Ac1055,Gp130,Il-6rb
General protein information	Preferred Names interleukin 6 signal transducer Names interleukin-6 receptor subunit beta IL-6 receptor subunit beta IL-6R subunit beta membrane glycoprotein 130 oncostatin-M receptor subunit alpha
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q14
Summary	IL-6 signal transducing molecule [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001008725.3	NP_001008725.2	interleukin-6 receptor subunit beta precursor
XM_008760736.2	XP_008758958.1	interleukin-6 receptor subunit beta isoform X1
XM_017590638.1	XP_017446127.1	interleukin-6 receptor subunit beta isoform X1
XM_006231928.3	XP_006231990.1	interleukin-6 receptor subunit beta isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	IL6ST	NP_002175.2
Pan troglodytes (chimpanzee)	IL6ST	XP_001144416.1
Rattus norvegicus (Norway rat)	Il6st	NP_001008725.2
Danio rerio (zebrafish)	il6st	NP_001106976.1
Xenopus tropicalis (tropical clawed frog)	il6st	XP_002940276.2
	IL6ST	XP_001100601.1
Canis lupus familiaris (dog)	IL6ST	XP_005617454.1
Mus musculus (house mouse)	Il6st	NP_034690.3
Bos taurus (cattle)	IL6ST	XP_002696368.3
Gallus gallus (chicken)	IL6ST	NP_990202.1

Gene Ontology
Bibliography

Related articles in PubMed

Pulmonary instillation of MWCNT increases lung permeability, decreases gp130 expression in the lungs, and initiates cardiovascular IL-6 transsignaling.
Thompson LC, Holland NA, Snyder RJ, Luo B, Becak DP, Odom JT, Harrison BS, Brown JM, Gowdy KM, Wingard CJ
American journal of physiology. Lung cellular and molecular physiology310(2)L142-54(2016 Jan)

Identification of Spinal Cord MicroRNA and Gene Signatures in a Model of Chronic Stress-Induced Visceral Hyperalgesia in Rat.
Bradesi S, Karagiannides I, Bakirtzi K, Joshi SM, Koukos G, Iliopoulos D, Pothoulakis C, Mayer EA
PloS one10(7)e0130938(2015)

The inhibition of N-glycosylation of glycoprotein 130 molecule abolishes STAT3 activation by IL-6 family cytokines in cultured cardiac myocytes.
Matsuo R, Morihara H, Mohri T, Murasawa S, Takewaki K, Nakayama H, Maeda M, Fujio Y
PloS one9(10)e111097(2014)

Biochemical and functional analyses of gp130 mutants unveil JAK1 as a novel therapeutic target in human inflammatory hepatocellular adenoma.
Poussin K, Pilati C, Couchy G, Calderaro J, Bioulac-Sage P, Bacq Y, Paradis V, Leteurtre E, Sturm N, Ramos J, Guettier C, Bardier-Dupas A, Boulai A, Wendum D, Selves J, Izard T, Nault JC, Zucman-Rossi J
Oncoimmunology2(12)e27090(2013 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

pulmonary exposure to MWCNT can manifest as a reduced epithelial barrier and activator of vascular gp130-associated transsignaling that may promote susceptibility to cardiovascular derangements
Title: Pulmonary instillation of MWCNT increases lung permeability, decreases gp130 expression in the lungs, and initiates cardiovascular IL-6 transsignaling.

findings suggest a link between miR-17-5p increased expression and gp130/STAT3 activation providing new insight into the possible mechanisms mediating the effect of chronic stress on neuroinflammation
Title: Identification of Spinal Cord MicroRNA and Gene Signatures in a Model of Chronic Stress-Induced Visceral Hyperalgesia in Rat.

In the chronic kidney disease-cardiac hypertrophy model exercise rescues cardiac disease via cardiotrophin-1/LIFR/gp 130/JAK/STAT3 pathway.
Title: Exercise rescued chronic kidney disease by attenuating cardiac hypertrophy through the cardiotrophin-1 -> LIFR/gp 130 -> JAK/STAT3 pathway.

glycosylation of gp130 is essential for signal transduction of IL-6 family cytokines in cardiomyocytes
Title: The inhibition of N-glycosylation of glycoprotein 130 molecule abolishes STAT3 activation by IL-6 family cytokines in cultured cardiac myocytes.

Enhanced SOCS1 myocardial signalling is associated with accelerated transition from cardiac hypertrophy to heart failure via gp130/JAK1/STAT3 pathway.
Title: SOCS1 gene transfer accelerates the transition to heart failure through the inhibition of the gp130/JAK/STAT pathway.

The following Il6st gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Il6st cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa11071	NM_001008725.3 Latest version!	Rattus norvegicus interleukin 6 signal transducer (Il6st), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
ORa24402	XM_008760736.2 Latest version!	Rattus norvegicus interleukin 6 signal transducer (Il6st), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
ORa24402	XM_006231928.3 Latest version!	Rattus norvegicus interleukin 6 signal transducer (Il6st), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
ORa24402	XM_017590638.1 Latest version!	Rattus norvegicus interleukin 6 signal transducer (Il6st), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Il6st ( NM_001008725.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001008725.2 Rattus norvegicus interleukin 6 signal transducer (Il6st), mRNA.

Price & Availability↑

CloneID	ORa11071
Clone ID Related Accession (Same CDS sequence)	NM_001008725.3
Accession Version	NM_001008725.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2757bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Rattus norvegicus(Norway rat)
Product	interleukin-6 receptor subunit beta precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07008118.1. On Jul 8, 2010 this sequence version replaced NM_001008725.2. Sequence Note: This RefSeq record was created from genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M92340.1, JQ013730.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCGCAC TAAGGATCTG GCTAATGCAA GCTTTGCTTA TTTTCCTCAC TACTGAGTCT 
ATAGGTCAAC TTGTGGAACC ATGTGGTTAT ATCTACCCTG AGTTTCCAGT TGTCCAGCGT 
GGCTCTAACT TCACTGCCAC TTGTGTGCTA AAGGAGAAGT GTCTGCAGGT GTACTCCGTG 
AATGCCACTT ACATCGTGTG GAAGACAAAC CATGTTGCCG TTCCTAAGGA GCAGGTCACA 
GTCATCAACA GAACGGCATC CAGTGTCACA TTCACAGACG TGGTCTTTCA GAACGTCCAG 
CTCACCTGCA ATATCCTGTC ATTTGGACAG ATCGAGCAGA ATGTGTATGG AATCACCATA 
CTTTCAGGCT ATCCTCCAGA TATACCTACA AATTTGAGTT GCATTGTGAA TGAGGGGAAG 
AACATGCTGT GTCAGTGGGA CCCAGGAAGG GAGACATACC TTGAAACAAA CTACACTTTG 
AAGTCAGAGT GGGCAACAGA GAAGTTTCCT GATTGTCGAA CAAAGCATGG CACGAGCTCC 
TGCATGATGG GCTATACCCC CATCTATTTT GTCAACATCG AGGTCTGGGT GGAGGCCGAG 
AATGCCCTTG GGAATGTCTC CTCAGAGCCT ATCAATTTTG ACCCCGTGGA TAAAGTGAAA 
CCCAGCCCAC CTCATAATTT GTCAGTGACC AACTCAGAAG AATTATCCAG TATATTAAAA 
CTAGCATGGG TCAATTCAGG TTTGGACAGT ATTTTAAGGC TGAAGTCGGA CATCCAATAT 
AGGACCAAAG ATGCCTCAAC TTGGATTCAG GTCCCTCTTG AAGATACAGT GTCTCCCCGG 
ACTTCGTTCA CTGTTCAGGA TCTCAAGCCT TTTACAGAAT ATGTGTTTAG GATTCGGTCC 
ATTAAGGAGA ATGGGAAGGG CTACTGGAGT GACTGGAGTG AGGAGGCGAG CGGGACCACA 
TATGAAGACA GACCATCCAA AGCGCCAAGT TTCTGGTATA AGGTAAATGC AAACCATCCA 
CAGGAGTATA GGTCTGCACG GCTCATATGG AAGACATTGC CCCTTTCTGA AGCCAATGGG 
AAGATCTTGG ATTATGAAGT GGTTCTTACA CAGTCCAAGT CAGTTTCGCA AACTTACACA 
GTTAACGGCA CAGAGTTGAT AGTAAACCTC ACCAATAACC GCTATGTAGC GTCTCTAGCA 
GCAAGAAATG TGGTCGGCAA GTCCCCTGCA ACCGTCCTCA CCATCCCCGG CTCCCACTTC 
AAAGCTTCTC ACCCCGTAGT GGATCTTAAA GCATTTCCAA AAGATAACCT GCTCTGGGTA 
GAATGGACAC CGCCATCTAA ACCTGTGAAC AAATACATAC TAGAGTGGTG TGTGTTGTCA 
GAGAACTCAC CCTGCATCCC AGACTGGCAG CAAGAAGATG GCACTGTGAA TCGGACCCAC 
TTAAGAGGAA GCCTACTGGA GAGCAAGTGC TATCTGATCA CAGTAACCCC AGTGTTTCCC 
GGTGGGCCTG GAAGCCCTGA GTCCATGAAG GCGTACCTCA AACAAGCAGC TCCTTCTAAA 
GGACCGACTG TTCGGACAAA GAAAGTGGGG AAAAATGAAG CTGTCTTAGA GTGGGACCAT 
CTTCCTGTTG ATGTCCAGAA CGGATTCATT AGAAACTACT CCATATCTTA TAGAACCAGT 
GTTGGAAAAG AAATGGTTGT GCGTGTGGAT TCTTCTCACA CAGAATACAC ACTGTCCTCT 
TTGAGTAGCG ATACACTGTA CATGGTCCAC ATGGCAGCAT ACACAGAAGA AGGTGGGAAG 
GATGGGCCGG AATTCACTTT TACAACACTA AAGTTTGCTC AAGGAGAAAT CGAAGCCATA 
GTCGTGCCTG TGTGCTTAGC TTTCCTCCTG ACAACGCTGC TGGGAGTCTT GTTCTGCTTT 
AATAAACGAG ACCTAATTAA AAAACACATC TGGCCGAATG TCCCAGATCC TTCAAAGAGT 
CATATTGCCC AGTGGTCACC TCACACCCCC CCAAGGCACA ATTTTAACTC CAAAGATCAG 
ATGTACTCAG ATGCCAATTT CACTGACGTA AGCGTTGTGG AAATAGAAGC AAACAACAAA 
AAGCCTTGTC CAGATGACCT GAAATCCTTG GACCTGTTCA AGAAGGAGAA AATAAGTACA 
GAAGGGCACA GCAGTGGCAT TGGGGGGTCC TCGTGCATGT CCTCTTCTAG GCCCAGCATC 
TCCAGCAGTG AGGAGAACGA GTCTGCTCAG AGCACCGCAA GCACGGTGCA GTACTCCACC 
GTGGTGCACA GCGGCTACAG GCACCAGGTG CCGTCAGTGC AAGTGTTCTC AAGGTCTGAG 
TCCACCCAGC CCCTGCTAGA CTCCGAGGAG CGGCCAGAGG ACCTGCAGCT GGTGGATAGT 
GTGGACAGCG GTGACGAGAT CTTACCCAGG CAACAGTATT TCAAACAAAG CTGCAGTCAG 
CCTGGAGCCA GTCCAGATGT TTCACACTTC GAAAGGTCAA GCCAGGTTCC GTCAGGCAGT 
GAGGAGGATT TTGTCAGACT GAAACAGCAG CAGGTTTCAG ATCACATTTC AGAGCCCTAT 
GGCTCCGAGC AACGGAGGCT GTTTCAGGAA GGTTCTGTGG CAGATGCTCT TGGCACAGGG 
ACTGATGGAC AGATAGAGAG ATTCGAATCT GTTGGAATGG AGACAGCGAT GGATGAAGAC 
ATTTCCAAAA GTTACTTGCC ACAGACTGTA AGACAAGGTG GCTACATGCC ACAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001008725.2
CDS	17..2773
Translation	MSALRIWLMQALLIFLTTESIGQLVEPCGYIYPEFPVVQRGSNFTATCVLKEKCLQVYSVNATYIVWKTNHVAVPKEQVTVINRTASSVTFTDVVFQNVQLTCNILSFGQIEQNVYGITILSGYPPDIPTNLSCIVNEGKNMLCQWDPGRETYLETNYTLKSEWATEKFPDCRTKHGTSSCMMGYTPIYFVNIEVWVEAENALGNVSSEPINFDPVDKVKPSPPHNLSVTNSEELSSILKLAWVNSGLDSILRLKSDIQYRTKDASTWIQVPLEDTVSPRTSFTVQDLKPFTEYVFRIRSIKENGKGYWSDWSEEASGTTYEDRPSKAPSFWYKVNANHPQEYRSARLIWKTLPLSEANGKILDYEVVLTQSKSVSQTYTVNGTELIVNLTNNRYVASLAARNVVGKSPATVLTIPGSHFKASHPVVDLKAFPKDNLLWVEWTPPSKPVNKYILEWCVLSENSPCIPDWQQEDGTVNRTHLRGSLLESKCYLITVTPVFPGGPGSPESMKAYLKQAAPSKGPTVRTKKVGKNEAVLEWDHLPVDVQNGFIRNYSISYRTSVGKEMVVRVDSSHTEYTLSSLSSDTLYMVHMAAYTEEGGKDGPEFTFTTLKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDANFTDVSVVEIEANNKKPCPDDLKSLDLFKKEKISTEGHSSGIGGSSCMSSSRPSISSSEENESAQSTASTVQYSTVVHSGYRHQVPSVQVFSRSESTQPLLDSEERPEDLQLVDSVDSGDEILPRQQYFKQSCSQPGASPDVSHFERSSQVPSGSEEDFVRLKQQQVSDHISEPYGSEQRRLFQEGSVADALGTGTDGQIERFESVGMETAMDEDISKSYLPQTVRQGGYMPQ

Target ORF information:

RefSeq Version	NM_001008725.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus interleukin 6 signal transducer (Il6st), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001008725.3

ORF Insert Sequence:

ATGTCCGCAC TAAGGATCTG GCTAATGCAA GCTTTGCTTA TTTTCCTCAC TACTGAGTCT 
ATAGGTCAAC TTGTGGAACC ATGTGGTTAT ATCTACCCTG AGTTTCCAGT TGTCCAGCGT 
GGCTCTAACT TCACTGCCAC TTGTGTGCTA AAGGAGAAGT GTCTGCAGGT GTACTCCGTG 
AATGCCACTT ACATCGTGTG GAAGACAAAC CATGTTGCCG TTCCTAAGGA GCAGGTCACA 
GTCATCAACA GAACGGCATC CAGTGTCACA TTCACAGACG TGGTCTTTCA GAACGTCCAG 
CTCACCTGCA ATATCCTGTC ATTTGGACAG ATCGAGCAGA ATGTGTATGG AATCACCATA 
CTTTCAGGCT ATCCTCCAGA TATACCTACA AATTTGAGTT GCATTGTGAA TGAGGGGAAG 
AACATGCTGT GTCAGTGGGA CCCAGGAAGG GAGACATACC TTGAAACAAA CTACACTTTG 
AAGTCAGAGT GGGCAACAGA GAAGTTTCCT GATTGTCGAA CAAAGCATGG CACGAGCTCC 
TGCATGATGG GCTATACCCC CATCTATTTT GTCAACATCG AGGTCTGGGT GGAGGCCGAG 
AATGCCCTTG GGAATGTCTC CTCAGAGCCT ATCAATTTTG ACCCCGTGGA TAAAGTGAAA 
CCCAGCCCAC CTCATAATTT GTCAGTGACC AACTCAGAAG AATTATCCAG TATATTAAAA 
CTAGCATGGG TCAATTCAGG TTTGGACAGT ATTTTAAGGC TGAAGTCGGA CATCCAATAT 
AGGACCAAAG ATGCCTCAAC TTGGATTCAG GTCCCTCTTG AAGATACAGT GTCTCCCCGG 
ACTTCGTTCA CTGTTCAGGA TCTCAAGCCT TTTACAGAAT ATGTGTTTAG GATTCGGTCC 
ATTAAGGAGA ATGGGAAGGG CTACTGGAGT GACTGGAGTG AGGAGGCGAG CGGGACCACA 
TATGAAGACA GACCATCCAA AGCGCCAAGT TTCTGGTATA AGGTAAATGC AAACCATCCA 
CAGGAGTATA GGTCTGCACG GCTCATATGG AAGACATTGC CCCTTTCTGA AGCCAATGGG 
AAGATCTTGG ATTATGAAGT GGTTCTTACA CAGTCCAAGT CAGTTTCGCA AACTTACACA 
GTTAACGGCA CAGAGTTGAT AGTAAACCTC ACCAATAACC GCTATGTAGC GTCTCTAGCA 
GCAAGAAATG TGGTCGGCAA GTCCCCTGCA ACCGTCCTCA CCATCCCCGG CTCCCACTTC 
AAAGCTTCTC ACCCCGTAGT GGATCTTAAA GCATTTCCAA AAGATAACCT GCTCTGGGTA 
GAATGGACAC CGCCATCTAA ACCTGTGAAC AAATACATAC TAGAGTGGTG TGTGTTGTCA 
GAGAACTCAC CCTGCATCCC AGACTGGCAG CAAGAAGATG GCACTGTGAA TCGGACCCAC 
TTAAGAGGAA GCCTACTGGA GAGCAAGTGC TATCTGATCA CAGTAACCCC AGTGTTTCCC 
GGTGGGCCTG GAAGCCCTGA GTCCATGAAG GCGTACCTCA AACAAGCAGC TCCTTCTAAA 
GGACCGACTG TTCGGACAAA GAAAGTGGGG AAAAATGAAG CTGTCTTAGA GTGGGACCAT 
CTTCCTGTTG ATGTCCAGAA CGGATTCATT AGAAACTACT CCATATCTTA TAGAACCAGT 
GTTGGAAAAG AAATGGTTGT GCGTGTGGAT TCTTCTCACA CAGAATACAC ACTGTCCTCT 
TTGAGTAGCG ATACACTGTA CATGGTCCAC ATGGCAGCAT ACACAGAAGA AGGTGGGAAG 
GATGGGCCGG AATTCACTTT TACAACACTA AAGTTTGCTC AAGGAGAAAT CGAAGCCATA 
GTCGTGCCTG TGTGCTTAGC TTTCCTCCTG ACAACGCTGC TGGGAGTCTT GTTCTGCTTT 
AATAAACGAG ACCTAATTAA AAAACACATC TGGCCGAATG TCCCAGATCC TTCAAAGAGT 
CATATTGCCC AGTGGTCACC TCACACCCCC CCAAGGCACA ATTTTAACTC CAAAGATCAG 
ATGTACTCAG ATGCCAATTT CACTGACGTA AGCGTTGTGG AAATAGAAGC AAACAACAAA 
AAGCCTTGTC CAGATGACCT GAAATCCTTG GACCTGTTCA AGAAGGAGAA AATAAGTACA 
GAAGGGCACA GCAGTGGCAT TGGGGGGTCC TCGTGCATGT CCTCTTCTAG GCCCAGCATC 
TCCAGCAGTG AGGAGAACGA GTCTGCTCAG AGCACCGCAA GCACGGTGCA GTACTCCACC 
GTGGTGCACA GCGGCTACAG GCACCAGGTG CCGTCAGTGC AAGTGTTCTC AAGGTCTGAG 
TCCACCCAGC CCCTGCTAGA CTCCGAGGAG CGGCCAGAGG ACCTGCAGCT GGTGGATAGT 
GTGGACAGCG GTGACGAGAT CTTACCCAGG CAACAGTATT TCAAACAAAG CTGCAGTCAG 
CCTGGAGCCA GTCCAGATGT TTCACACTTC GAAAGGTCAA GCCAGGTTCC GTCAGGCAGT 
GAGGAGGATT TTGTCAGACT GAAACAGCAG CAGGTTTCAG ATCACATTTC AGAGCCCTAT 
GGCTCCGAGC AACGGAGGCT GTTTCAGGAA GGTTCTGTGG CAGATGCTCT TGGCACAGGG 
ACTGATGGAC AGATAGAGAG ATTCGAATCT GTTGGAATGG AGACAGCGAT GGATGAAGAC 
ATTTCCAAAA GTTACTTGCC ACAGACTGTA AGACAAGGTG GCTACATGCC ACAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Il6st ( XM_008760736.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008758958.1 Rattus norvegicus interleukin 6 signal transducer (Il6st), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa24402
Clone ID Related Accession (Same CDS sequence)	XM_008760736.2 , XM_017590638.1 , XM_006231928.3
Accession Version	XM_008760736.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2805bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	interleukin-6 receptor subunit beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008760736.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTTATC AGTTCTTAGG TTTGTGTATT GGGAGCATCC CTTGCAAGAT GTCCGCACTA 
AGGATCTGGC TAATGCAAGC TTTGCTTATT TTCCTCACTA CTGAGTCTAT AGGTCAACTT 
GTGGAACCAT GTGGTTATAT CTACCCTGAG TTTCCAGTTG TCCAGCGTGG CTCTAACTTC 
ACTGCCACTT GTGTGCTAAA GGAGAAGTGT CTGCAGGTGT ACTCCGTGAA TGCCACTTAC 
ATCGTGTGGA AGACAAACCA TGTTGCCGTT CCTAAGGAGC AGGTCACAGT CATCAACAGA 
ACGGCATCCA GTGTCACATT CACAGACGTG GTCTTTCAGA ACGTCCAGCT CACCTGCAAT 
ATCCTGTCAT TTGGACAGAT CGAGCAGAAT GTGTATGGAA TCACCATACT TTCAGGCTAT 
CCTCCAGATA TACCTACAAA TTTGAGTTGC ATTGTGAATG AGGGGAAGAA CATGCTGTGT 
CAGTGGGACC CAGGAAGGGA GACATACCTT GAAACAAACT ACACTTTGAA GTCAGAGTGG 
GCAACAGAGA AGTTTCCTGA TTGTCGAACA AAGCATGGCA CGAGCTCCTG CATGATGGGC 
TATACCCCCA TCTATTTTGT CAACATCGAG GTCTGGGTGG AGGCCGAGAA TGCCCTTGGG 
AATGTCTCCT CAGAGCCTAT CAATTTTGAC CCCGTGGATA AAGTGAAACC CAGCCCACCT 
CATAATTTGT CAGTGACCAA CTCAGAAGAA TTATCCAGTA TATTAAAACT AGCATGGGTC 
AATTCAGGTT TGGACAGTAT TTTAAGGCTG AAGTCGGACA TCCAATATAG GACCAAAGAT 
GCCTCAACTT GGATTCAGGT CCCTCTTGAA GATACAGTGT CTCCCCGGAC TTCGTTCACT 
GTTCAGGATC TCAAGCCTTT TACAGAATAT GTGTTTAGGA TTCGGTCCAT TAAGGAGAAT 
GGGAAGGGCT ACTGGAGTGA CTGGAGTGAG GAGGCGAGCG GGACCACATA TGAAGACAGA 
CCATCCAAAG CGCCAAGTTT CTGGTATAAG GTAAATGCAA ACCATCCACA GGAGTATAGG 
TCTGCACGGC TCATATGGAA GACATTGCCC CTTTCTGAAG CCAATGGGAA GATCTTGGAT 
TATGAAGTGG TTCTTACACA GTCCAAGTCA GTTTCGCAAA CTTACACAGT TAACGGCACA 
GAGTTGATAG TAAACCTCAC CAATAACCGC TATGTAGCGT CTCTAGCAGC AAGAAATGTG 
GTCGGCAAGT CCCCTGCAAC CGTCCTCACC ATCCCCGGCT CCCACTTCAA AGCTTCTCAC 
CCCGTAGTGG ATCTTAAAGC ATTTCCAAAA GATAACCTGC TCTGGGTAGA ATGGACACCG 
CCATCTAAAC CTGTGAACAA ATACATACTA GAGTGGTGTG TGTTGTCAGA GAACTCACCC 
TGCATCCCAG ACTGGCAGCA AGAAGATGGC ACTGTGAATC GGACCCACTT AAGAGGAAGC 
CTACTGGAGA GCAAGTGCTA TCTGATCACA GTAACCCCAG TGTTTCCCGG TGGGCCTGGA 
AGCCCTGAGT CCATGAAGGC GTACCTCAAA CAAGCAGCTC CTTCTAAAGG ACCGACTGTT 
CGGACAAAGA AAGTGGGGAA AAATGAAGCT GTCTTAGAGT GGGACCATCT TCCTGTTGAT 
GTCCAGAACG GATTCATTAG AAACTACTCC ATATCTTATA GAACCAGTGT TGGAAAAGAA 
ATGGTTGTGC GTGTGGATTC TTCTCACACA GAATACACAC TGTCCTCTTT GAGTAGCGAT 
ACACTGTACA TGGTCCACAT GGCAGCATAC ACAGAAGAAG GTGGGAAGGA TGGGCCGGAA 
TTCACTTTTA CAACACTAAA GTTTGCTCAA GGAGAAATCG AAGCCATAGT CGTGCCTGTG 
TGCTTAGCTT TCCTCCTGAC AACGCTGCTG GGAGTCTTGT TCTGCTTTAA TAAACGAGAC 
CTAATTAAAA AACACATCTG GCCGAATGTC CCAGATCCTT CAAAGAGTCA TATTGCCCAG 
TGGTCACCTC ACACCCCCCC AAGGCACAAT TTTAACTCCA AAGATCAGAT GTACTCAGAT 
GCCAATTTCA CTGACGTAAG CGTTGTGGAA ATAGAAGCAA ACAACAAAAA GCCTTGTCCA 
GATGACCTGA AATCCTTGGA CCTGTTCAAG AAGGAGAAAA TAAGTACAGA AGGGCACAGC 
AGTGGCATTG GGGGGTCCTC GTGCATGTCC TCTTCTAGGC CCAGCATCTC CAGCAGTGAG 
GAGAACGAGT CTGCTCAGAG CACCGCAAGC ACGGTGCAGT ACTCCACCGT GGTGCACAGC 
GGCTACAGGC ACCAGGTGCC GTCAGTGCAA GTGTTCTCAA GGTCTGAGTC CACCCAGCCC 
CTGCTAGACT CCGAGGAGCG GCCAGAGGAC CTGCAGCTGG TGGATAGTGT GGACAGCGGT 
GACGAGATCT TACCCAGGCA ACAGTATTTC AAACAAAGCT GCAGTCAGCC TGGAGCCAGT 
CCAGATGTTT CACACTTCGA AAGGTCAAGC CAGGTTCCGT CAGGCAGTGA GGAGGATTTT 
GTCAGACTGA AACAGCAGCA GGTTTCAGAT CACATTTCAG AGCCCTATGG CTCCGAGCAA 
CGGAGGCTGT TTCAGGAAGG TTCTGTGGCA GATGCTCTTG GCACAGGGAC TGATGGACAG 
ATAGAGAGAT TCGAATCTGT TGGAATGGAG ACAGCGATGG ATGAAGACAT TTCCAAAAGT 
TACTTGCCAC AGACTGTAAG ACAAGGTGGC TACATGCCAC AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008758958.1
CDS	1067..3871
Translation	MPYQFLGLCIGSIPCKMSALRIWLMQALLIFLTTESIGQLVEPCGYIYPEFPVVQRGSNFTATCVLKEKCLQVYSVNATYIVWKTNHVAVPKEQVTVINRTASSVTFTDVVFQNVQLTCNILSFGQIEQNVYGITILSGYPPDIPTNLSCIVNEGKNMLCQWDPGRETYLETNYTLKSEWATEKFPDCRTKHGTSSCMMGYTPIYFVNIEVWVEAENALGNVSSEPINFDPVDKVKPSPPHNLSVTNSEELSSILKLAWVNSGLDSILRLKSDIQYRTKDASTWIQVPLEDTVSPRTSFTVQDLKPFTEYVFRIRSIKENGKGYWSDWSEEASGTTYEDRPSKAPSFWYKVNANHPQEYRSARLIWKTLPLSEANGKILDYEVVLTQSKSVSQTYTVNGTELIVNLTNNRYVASLAARNVVGKSPATVLTIPGSHFKASHPVVDLKAFPKDNLLWVEWTPPSKPVNKYILEWCVLSENSPCIPDWQQEDGTVNRTHLRGSLLESKCYLITVTPVFPGGPGSPESMKAYLKQAAPSKGPTVRTKKVGKNEAVLEWDHLPVDVQNGFIRNYSISYRTSVGKEMVVRVDSSHTEYTLSSLSSDTLYMVHMAAYTEEGGKDGPEFTFTTLKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDANFTDVSVVEIEANNKKPCPDDLKSLDLFKKEKISTEGHSSGIGGSSCMSSSRPSISSSEENESAQSTASTVQYSTVVHSGYRHQVPSVQVFSRSESTQPLLDSEERPEDLQLVDSVDSGDEILPRQQYFKQSCSQPGASPDVSHFERSSQVPSGSEEDFVRLKQQQVSDHISEPYGSEQRRLFQEGSVADALGTGTDGQIERFESVGMETAMDEDISKSYLPQTVRQGGYMPQ

Target ORF information:

RefSeq Version	XM_008760736.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus interleukin 6 signal transducer (Il6st), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008760736.2

ORF Insert Sequence:

ATGCCTTATC AGTTCTTAGG TTTGTGTATT GGGAGCATCC CTTGCAAGAT GTCCGCACTA 
AGGATCTGGC TAATGCAAGC TTTGCTTATT TTCCTCACTA CTGAGTCTAT AGGTCAACTT 
GTGGAACCAT GTGGTTATAT CTACCCTGAG TTTCCAGTTG TCCAGCGTGG CTCTAACTTC 
ACTGCCACTT GTGTGCTAAA GGAGAAGTGT CTGCAGGTGT ACTCCGTGAA TGCCACTTAC 
ATCGTGTGGA AGACAAACCA TGTTGCCGTT CCTAAGGAGC AGGTCACAGT CATCAACAGA 
ACGGCATCCA GTGTCACATT CACAGACGTG GTCTTTCAGA ACGTCCAGCT CACCTGCAAT 
ATCCTGTCAT TTGGACAGAT CGAGCAGAAT GTGTATGGAA TCACCATACT TTCAGGCTAT 
CCTCCAGATA TACCTACAAA TTTGAGTTGC ATTGTGAATG AGGGGAAGAA CATGCTGTGT 
CAGTGGGACC CAGGAAGGGA GACATACCTT GAAACAAACT ACACTTTGAA GTCAGAGTGG 
GCAACAGAGA AGTTTCCTGA TTGTCGAACA AAGCATGGCA CGAGCTCCTG CATGATGGGC 
TATACCCCCA TCTATTTTGT CAACATCGAG GTCTGGGTGG AGGCCGAGAA TGCCCTTGGG 
AATGTCTCCT CAGAGCCTAT CAATTTTGAC CCCGTGGATA AAGTGAAACC CAGCCCACCT 
CATAATTTGT CAGTGACCAA CTCAGAAGAA TTATCCAGTA TATTAAAACT AGCATGGGTC 
AATTCAGGTT TGGACAGTAT TTTAAGGCTG AAGTCGGACA TCCAATATAG GACCAAAGAT 
GCCTCAACTT GGATTCAGGT CCCTCTTGAA GATACAGTGT CTCCCCGGAC TTCGTTCACT 
GTTCAGGATC TCAAGCCTTT TACAGAATAT GTGTTTAGGA TTCGGTCCAT TAAGGAGAAT 
GGGAAGGGCT ACTGGAGTGA CTGGAGTGAG GAGGCGAGCG GGACCACATA TGAAGACAGA 
CCATCCAAAG CGCCAAGTTT CTGGTATAAG GTAAATGCAA ACCATCCACA GGAGTATAGG 
TCTGCACGGC TCATATGGAA GACATTGCCC CTTTCTGAAG CCAATGGGAA GATCTTGGAT 
TATGAAGTGG TTCTTACACA GTCCAAGTCA GTTTCGCAAA CTTACACAGT TAACGGCACA 
GAGTTGATAG TAAACCTCAC CAATAACCGC TATGTAGCGT CTCTAGCAGC AAGAAATGTG 
GTCGGCAAGT CCCCTGCAAC CGTCCTCACC ATCCCCGGCT CCCACTTCAA AGCTTCTCAC 
CCCGTAGTGG ATCTTAAAGC ATTTCCAAAA GATAACCTGC TCTGGGTAGA ATGGACACCG 
CCATCTAAAC CTGTGAACAA ATACATACTA GAGTGGTGTG TGTTGTCAGA GAACTCACCC 
TGCATCCCAG ACTGGCAGCA AGAAGATGGC ACTGTGAATC GGACCCACTT AAGAGGAAGC 
CTACTGGAGA GCAAGTGCTA TCTGATCACA GTAACCCCAG TGTTTCCCGG TGGGCCTGGA 
AGCCCTGAGT CCATGAAGGC GTACCTCAAA CAAGCAGCTC CTTCTAAAGG ACCGACTGTT 
CGGACAAAGA AAGTGGGGAA AAATGAAGCT GTCTTAGAGT GGGACCATCT TCCTGTTGAT 
GTCCAGAACG GATTCATTAG AAACTACTCC ATATCTTATA GAACCAGTGT TGGAAAAGAA 
ATGGTTGTGC GTGTGGATTC TTCTCACACA GAATACACAC TGTCCTCTTT GAGTAGCGAT 
ACACTGTACA TGGTCCACAT GGCAGCATAC ACAGAAGAAG GTGGGAAGGA TGGGCCGGAA 
TTCACTTTTA CAACACTAAA GTTTGCTCAA GGAGAAATCG AAGCCATAGT CGTGCCTGTG 
TGCTTAGCTT TCCTCCTGAC AACGCTGCTG GGAGTCTTGT TCTGCTTTAA TAAACGAGAC 
CTAATTAAAA AACACATCTG GCCGAATGTC CCAGATCCTT CAAAGAGTCA TATTGCCCAG 
TGGTCACCTC ACACCCCCCC AAGGCACAAT TTTAACTCCA AAGATCAGAT GTACTCAGAT 
GCCAATTTCA CTGACGTAAG CGTTGTGGAA ATAGAAGCAA ACAACAAAAA GCCTTGTCCA 
GATGACCTGA AATCCTTGGA CCTGTTCAAG AAGGAGAAAA TAAGTACAGA AGGGCACAGC 
AGTGGCATTG GGGGGTCCTC GTGCATGTCC TCTTCTAGGC CCAGCATCTC CAGCAGTGAG 
GAGAACGAGT CTGCTCAGAG CACCGCAAGC ACGGTGCAGT ACTCCACCGT GGTGCACAGC 
GGCTACAGGC ACCAGGTGCC GTCAGTGCAA GTGTTCTCAA GGTCTGAGTC CACCCAGCCC 
CTGCTAGACT CCGAGGAGCG GCCAGAGGAC CTGCAGCTGG TGGATAGTGT GGACAGCGGT 
GACGAGATCT TACCCAGGCA ACAGTATTTC AAACAAAGCT GCAGTCAGCC TGGAGCCAGT 
CCAGATGTTT CACACTTCGA AAGGTCAAGC CAGGTTCCGT CAGGCAGTGA GGAGGATTTT 
GTCAGACTGA AACAGCAGCA GGTTTCAGAT CACATTTCAG AGCCCTATGG CTCCGAGCAA 
CGGAGGCTGT TTCAGGAAGG TTCTGTGGCA GATGCTCTTG GCACAGGGAC TGATGGACAG 
ATAGAGAGAT TCGAATCTGT TGGAATGGAG ACAGCGATGG ATGAAGACAT TTCCAAAAGT 
TACTTGCCAC AGACTGTAAG ACAAGGTGGC TACATGCCAC AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Il6st ( XM_017590638.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017446127.1 Rattus norvegicus interleukin 6 signal transducer (Il6st), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa24402
Clone ID Related Accession (Same CDS sequence)	XM_008760736.2 , XM_017590638.1 , XM_006231928.3
Accession Version	XM_017590638.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2805bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	interleukin-6 receptor subunit beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTTATC AGTTCTTAGG TTTGTGTATT GGGAGCATCC CTTGCAAGAT GTCCGCACTA 
AGGATCTGGC TAATGCAAGC TTTGCTTATT TTCCTCACTA CTGAGTCTAT AGGTCAACTT 
GTGGAACCAT GTGGTTATAT CTACCCTGAG TTTCCAGTTG TCCAGCGTGG CTCTAACTTC 
ACTGCCACTT GTGTGCTAAA GGAGAAGTGT CTGCAGGTGT ACTCCGTGAA TGCCACTTAC 
ATCGTGTGGA AGACAAACCA TGTTGCCGTT CCTAAGGAGC AGGTCACAGT CATCAACAGA 
ACGGCATCCA GTGTCACATT CACAGACGTG GTCTTTCAGA ACGTCCAGCT CACCTGCAAT 
ATCCTGTCAT TTGGACAGAT CGAGCAGAAT GTGTATGGAA TCACCATACT TTCAGGCTAT 
CCTCCAGATA TACCTACAAA TTTGAGTTGC ATTGTGAATG AGGGGAAGAA CATGCTGTGT 
CAGTGGGACC CAGGAAGGGA GACATACCTT GAAACAAACT ACACTTTGAA GTCAGAGTGG 
GCAACAGAGA AGTTTCCTGA TTGTCGAACA AAGCATGGCA CGAGCTCCTG CATGATGGGC 
TATACCCCCA TCTATTTTGT CAACATCGAG GTCTGGGTGG AGGCCGAGAA TGCCCTTGGG 
AATGTCTCCT CAGAGCCTAT CAATTTTGAC CCCGTGGATA AAGTGAAACC CAGCCCACCT 
CATAATTTGT CAGTGACCAA CTCAGAAGAA TTATCCAGTA TATTAAAACT AGCATGGGTC 
AATTCAGGTT TGGACAGTAT TTTAAGGCTG AAGTCGGACA TCCAATATAG GACCAAAGAT 
GCCTCAACTT GGATTCAGGT CCCTCTTGAA GATACAGTGT CTCCCCGGAC TTCGTTCACT 
GTTCAGGATC TCAAGCCTTT TACAGAATAT GTGTTTAGGA TTCGGTCCAT TAAGGAGAAT 
GGGAAGGGCT ACTGGAGTGA CTGGAGTGAG GAGGCGAGCG GGACCACATA TGAAGACAGA 
CCATCCAAAG CGCCAAGTTT CTGGTATAAG GTAAATGCAA ACCATCCACA GGAGTATAGG 
TCTGCACGGC TCATATGGAA GACATTGCCC CTTTCTGAAG CCAATGGGAA GATCTTGGAT 
TATGAAGTGG TTCTTACACA GTCCAAGTCA GTTTCGCAAA CTTACACAGT TAACGGCACA 
GAGTTGATAG TAAACCTCAC CAATAACCGC TATGTAGCGT CTCTAGCAGC AAGAAATGTG 
GTCGGCAAGT CCCCTGCAAC CGTCCTCACC ATCCCCGGCT CCCACTTCAA AGCTTCTCAC 
CCCGTAGTGG ATCTTAAAGC ATTTCCAAAA GATAACCTGC TCTGGGTAGA ATGGACACCG 
CCATCTAAAC CTGTGAACAA ATACATACTA GAGTGGTGTG TGTTGTCAGA GAACTCACCC 
TGCATCCCAG ACTGGCAGCA AGAAGATGGC ACTGTGAATC GGACCCACTT AAGAGGAAGC 
CTACTGGAGA GCAAGTGCTA TCTGATCACA GTAACCCCAG TGTTTCCCGG TGGGCCTGGA 
AGCCCTGAGT CCATGAAGGC GTACCTCAAA CAAGCAGCTC CTTCTAAAGG ACCGACTGTT 
CGGACAAAGA AAGTGGGGAA AAATGAAGCT GTCTTAGAGT GGGACCATCT TCCTGTTGAT 
GTCCAGAACG GATTCATTAG AAACTACTCC ATATCTTATA GAACCAGTGT TGGAAAAGAA 
ATGGTTGTGC GTGTGGATTC TTCTCACACA GAATACACAC TGTCCTCTTT GAGTAGCGAT 
ACACTGTACA TGGTCCACAT GGCAGCATAC ACAGAAGAAG GTGGGAAGGA TGGGCCGGAA 
TTCACTTTTA CAACACTAAA GTTTGCTCAA GGAGAAATCG AAGCCATAGT CGTGCCTGTG 
TGCTTAGCTT TCCTCCTGAC AACGCTGCTG GGAGTCTTGT TCTGCTTTAA TAAACGAGAC 
CTAATTAAAA AACACATCTG GCCGAATGTC CCAGATCCTT CAAAGAGTCA TATTGCCCAG 
TGGTCACCTC ACACCCCCCC AAGGCACAAT TTTAACTCCA AAGATCAGAT GTACTCAGAT 
GCCAATTTCA CTGACGTAAG CGTTGTGGAA ATAGAAGCAA ACAACAAAAA GCCTTGTCCA 
GATGACCTGA AATCCTTGGA CCTGTTCAAG AAGGAGAAAA TAAGTACAGA AGGGCACAGC 
AGTGGCATTG GGGGGTCCTC GTGCATGTCC TCTTCTAGGC CCAGCATCTC CAGCAGTGAG 
GAGAACGAGT CTGCTCAGAG CACCGCAAGC ACGGTGCAGT ACTCCACCGT GGTGCACAGC 
GGCTACAGGC ACCAGGTGCC GTCAGTGCAA GTGTTCTCAA GGTCTGAGTC CACCCAGCCC 
CTGCTAGACT CCGAGGAGCG GCCAGAGGAC CTGCAGCTGG TGGATAGTGT GGACAGCGGT 
GACGAGATCT TACCCAGGCA ACAGTATTTC AAACAAAGCT GCAGTCAGCC TGGAGCCAGT 
CCAGATGTTT CACACTTCGA AAGGTCAAGC CAGGTTCCGT CAGGCAGTGA GGAGGATTTT 
GTCAGACTGA AACAGCAGCA GGTTTCAGAT CACATTTCAG AGCCCTATGG CTCCGAGCAA 
CGGAGGCTGT TTCAGGAAGG TTCTGTGGCA GATGCTCTTG GCACAGGGAC TGATGGACAG 
ATAGAGAGAT TCGAATCTGT TGGAATGGAG ACAGCGATGG ATGAAGACAT TTCCAAAAGT 
TACTTGCCAC AGACTGTAAG ACAAGGTGGC TACATGCCAC AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017446127.1
CDS	1138..3942
Translation	MPYQFLGLCIGSIPCKMSALRIWLMQALLIFLTTESIGQLVEPCGYIYPEFPVVQRGSNFTATCVLKEKCLQVYSVNATYIVWKTNHVAVPKEQVTVINRTASSVTFTDVVFQNVQLTCNILSFGQIEQNVYGITILSGYPPDIPTNLSCIVNEGKNMLCQWDPGRETYLETNYTLKSEWATEKFPDCRTKHGTSSCMMGYTPIYFVNIEVWVEAENALGNVSSEPINFDPVDKVKPSPPHNLSVTNSEELSSILKLAWVNSGLDSILRLKSDIQYRTKDASTWIQVPLEDTVSPRTSFTVQDLKPFTEYVFRIRSIKENGKGYWSDWSEEASGTTYEDRPSKAPSFWYKVNANHPQEYRSARLIWKTLPLSEANGKILDYEVVLTQSKSVSQTYTVNGTELIVNLTNNRYVASLAARNVVGKSPATVLTIPGSHFKASHPVVDLKAFPKDNLLWVEWTPPSKPVNKYILEWCVLSENSPCIPDWQQEDGTVNRTHLRGSLLESKCYLITVTPVFPGGPGSPESMKAYLKQAAPSKGPTVRTKKVGKNEAVLEWDHLPVDVQNGFIRNYSISYRTSVGKEMVVRVDSSHTEYTLSSLSSDTLYMVHMAAYTEEGGKDGPEFTFTTLKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDANFTDVSVVEIEANNKKPCPDDLKSLDLFKKEKISTEGHSSGIGGSSCMSSSRPSISSSEENESAQSTASTVQYSTVVHSGYRHQVPSVQVFSRSESTQPLLDSEERPEDLQLVDSVDSGDEILPRQQYFKQSCSQPGASPDVSHFERSSQVPSGSEEDFVRLKQQQVSDHISEPYGSEQRRLFQEGSVADALGTGTDGQIERFESVGMETAMDEDISKSYLPQTVRQGGYMPQ

Target ORF information:

RefSeq Version	XM_017590638.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus interleukin 6 signal transducer (Il6st), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017590638.1

ORF Insert Sequence:

ATGCCTTATC AGTTCTTAGG TTTGTGTATT GGGAGCATCC CTTGCAAGAT GTCCGCACTA 
AGGATCTGGC TAATGCAAGC TTTGCTTATT TTCCTCACTA CTGAGTCTAT AGGTCAACTT 
GTGGAACCAT GTGGTTATAT CTACCCTGAG TTTCCAGTTG TCCAGCGTGG CTCTAACTTC 
ACTGCCACTT GTGTGCTAAA GGAGAAGTGT CTGCAGGTGT ACTCCGTGAA TGCCACTTAC 
ATCGTGTGGA AGACAAACCA TGTTGCCGTT CCTAAGGAGC AGGTCACAGT CATCAACAGA 
ACGGCATCCA GTGTCACATT CACAGACGTG GTCTTTCAGA ACGTCCAGCT CACCTGCAAT 
ATCCTGTCAT TTGGACAGAT CGAGCAGAAT GTGTATGGAA TCACCATACT TTCAGGCTAT 
CCTCCAGATA TACCTACAAA TTTGAGTTGC ATTGTGAATG AGGGGAAGAA CATGCTGTGT 
CAGTGGGACC CAGGAAGGGA GACATACCTT GAAACAAACT ACACTTTGAA GTCAGAGTGG 
GCAACAGAGA AGTTTCCTGA TTGTCGAACA AAGCATGGCA CGAGCTCCTG CATGATGGGC 
TATACCCCCA TCTATTTTGT CAACATCGAG GTCTGGGTGG AGGCCGAGAA TGCCCTTGGG 
AATGTCTCCT CAGAGCCTAT CAATTTTGAC CCCGTGGATA AAGTGAAACC CAGCCCACCT 
CATAATTTGT CAGTGACCAA CTCAGAAGAA TTATCCAGTA TATTAAAACT AGCATGGGTC 
AATTCAGGTT TGGACAGTAT TTTAAGGCTG AAGTCGGACA TCCAATATAG GACCAAAGAT 
GCCTCAACTT GGATTCAGGT CCCTCTTGAA GATACAGTGT CTCCCCGGAC TTCGTTCACT 
GTTCAGGATC TCAAGCCTTT TACAGAATAT GTGTTTAGGA TTCGGTCCAT TAAGGAGAAT 
GGGAAGGGCT ACTGGAGTGA CTGGAGTGAG GAGGCGAGCG GGACCACATA TGAAGACAGA 
CCATCCAAAG CGCCAAGTTT CTGGTATAAG GTAAATGCAA ACCATCCACA GGAGTATAGG 
TCTGCACGGC TCATATGGAA GACATTGCCC CTTTCTGAAG CCAATGGGAA GATCTTGGAT 
TATGAAGTGG TTCTTACACA GTCCAAGTCA GTTTCGCAAA CTTACACAGT TAACGGCACA 
GAGTTGATAG TAAACCTCAC CAATAACCGC TATGTAGCGT CTCTAGCAGC AAGAAATGTG 
GTCGGCAAGT CCCCTGCAAC CGTCCTCACC ATCCCCGGCT CCCACTTCAA AGCTTCTCAC 
CCCGTAGTGG ATCTTAAAGC ATTTCCAAAA GATAACCTGC TCTGGGTAGA ATGGACACCG 
CCATCTAAAC CTGTGAACAA ATACATACTA GAGTGGTGTG TGTTGTCAGA GAACTCACCC 
TGCATCCCAG ACTGGCAGCA AGAAGATGGC ACTGTGAATC GGACCCACTT AAGAGGAAGC 
CTACTGGAGA GCAAGTGCTA TCTGATCACA GTAACCCCAG TGTTTCCCGG TGGGCCTGGA 
AGCCCTGAGT CCATGAAGGC GTACCTCAAA CAAGCAGCTC CTTCTAAAGG ACCGACTGTT 
CGGACAAAGA AAGTGGGGAA AAATGAAGCT GTCTTAGAGT GGGACCATCT TCCTGTTGAT 
GTCCAGAACG GATTCATTAG AAACTACTCC ATATCTTATA GAACCAGTGT TGGAAAAGAA 
ATGGTTGTGC GTGTGGATTC TTCTCACACA GAATACACAC TGTCCTCTTT GAGTAGCGAT 
ACACTGTACA TGGTCCACAT GGCAGCATAC ACAGAAGAAG GTGGGAAGGA TGGGCCGGAA 
TTCACTTTTA CAACACTAAA GTTTGCTCAA GGAGAAATCG AAGCCATAGT CGTGCCTGTG 
TGCTTAGCTT TCCTCCTGAC AACGCTGCTG GGAGTCTTGT TCTGCTTTAA TAAACGAGAC 
CTAATTAAAA AACACATCTG GCCGAATGTC CCAGATCCTT CAAAGAGTCA TATTGCCCAG 
TGGTCACCTC ACACCCCCCC AAGGCACAAT TTTAACTCCA AAGATCAGAT GTACTCAGAT 
GCCAATTTCA CTGACGTAAG CGTTGTGGAA ATAGAAGCAA ACAACAAAAA GCCTTGTCCA 
GATGACCTGA AATCCTTGGA CCTGTTCAAG AAGGAGAAAA TAAGTACAGA AGGGCACAGC 
AGTGGCATTG GGGGGTCCTC GTGCATGTCC TCTTCTAGGC CCAGCATCTC CAGCAGTGAG 
GAGAACGAGT CTGCTCAGAG CACCGCAAGC ACGGTGCAGT ACTCCACCGT GGTGCACAGC 
GGCTACAGGC ACCAGGTGCC GTCAGTGCAA GTGTTCTCAA GGTCTGAGTC CACCCAGCCC 
CTGCTAGACT CCGAGGAGCG GCCAGAGGAC CTGCAGCTGG TGGATAGTGT GGACAGCGGT 
GACGAGATCT TACCCAGGCA ACAGTATTTC AAACAAAGCT GCAGTCAGCC TGGAGCCAGT 
CCAGATGTTT CACACTTCGA AAGGTCAAGC CAGGTTCCGT CAGGCAGTGA GGAGGATTTT 
GTCAGACTGA AACAGCAGCA GGTTTCAGAT CACATTTCAG AGCCCTATGG CTCCGAGCAA 
CGGAGGCTGT TTCAGGAAGG TTCTGTGGCA GATGCTCTTG GCACAGGGAC TGATGGACAG 
ATAGAGAGAT TCGAATCTGT TGGAATGGAG ACAGCGATGG ATGAAGACAT TTCCAAAAGT 
TACTTGCCAC AGACTGTAAG ACAAGGTGGC TACATGCCAC AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Il6st ( XM_006231928.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006231990.1 Rattus norvegicus interleukin 6 signal transducer (Il6st), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa24402
Clone ID Related Accession (Same CDS sequence)	XM_008760736.2 , XM_017590638.1 , XM_006231928.3
Accession Version	XM_006231928.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2805bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	interleukin-6 receptor subunit beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006231928.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTTATC AGTTCTTAGG TTTGTGTATT GGGAGCATCC CTTGCAAGAT GTCCGCACTA 
AGGATCTGGC TAATGCAAGC TTTGCTTATT TTCCTCACTA CTGAGTCTAT AGGTCAACTT 
GTGGAACCAT GTGGTTATAT CTACCCTGAG TTTCCAGTTG TCCAGCGTGG CTCTAACTTC 
ACTGCCACTT GTGTGCTAAA GGAGAAGTGT CTGCAGGTGT ACTCCGTGAA TGCCACTTAC 
ATCGTGTGGA AGACAAACCA TGTTGCCGTT CCTAAGGAGC AGGTCACAGT CATCAACAGA 
ACGGCATCCA GTGTCACATT CACAGACGTG GTCTTTCAGA ACGTCCAGCT CACCTGCAAT 
ATCCTGTCAT TTGGACAGAT CGAGCAGAAT GTGTATGGAA TCACCATACT TTCAGGCTAT 
CCTCCAGATA TACCTACAAA TTTGAGTTGC ATTGTGAATG AGGGGAAGAA CATGCTGTGT 
CAGTGGGACC CAGGAAGGGA GACATACCTT GAAACAAACT ACACTTTGAA GTCAGAGTGG 
GCAACAGAGA AGTTTCCTGA TTGTCGAACA AAGCATGGCA CGAGCTCCTG CATGATGGGC 
TATACCCCCA TCTATTTTGT CAACATCGAG GTCTGGGTGG AGGCCGAGAA TGCCCTTGGG 
AATGTCTCCT CAGAGCCTAT CAATTTTGAC CCCGTGGATA AAGTGAAACC CAGCCCACCT 
CATAATTTGT CAGTGACCAA CTCAGAAGAA TTATCCAGTA TATTAAAACT AGCATGGGTC 
AATTCAGGTT TGGACAGTAT TTTAAGGCTG AAGTCGGACA TCCAATATAG GACCAAAGAT 
GCCTCAACTT GGATTCAGGT CCCTCTTGAA GATACAGTGT CTCCCCGGAC TTCGTTCACT 
GTTCAGGATC TCAAGCCTTT TACAGAATAT GTGTTTAGGA TTCGGTCCAT TAAGGAGAAT 
GGGAAGGGCT ACTGGAGTGA CTGGAGTGAG GAGGCGAGCG GGACCACATA TGAAGACAGA 
CCATCCAAAG CGCCAAGTTT CTGGTATAAG GTAAATGCAA ACCATCCACA GGAGTATAGG 
TCTGCACGGC TCATATGGAA GACATTGCCC CTTTCTGAAG CCAATGGGAA GATCTTGGAT 
TATGAAGTGG TTCTTACACA GTCCAAGTCA GTTTCGCAAA CTTACACAGT TAACGGCACA 
GAGTTGATAG TAAACCTCAC CAATAACCGC TATGTAGCGT CTCTAGCAGC AAGAAATGTG 
GTCGGCAAGT CCCCTGCAAC CGTCCTCACC ATCCCCGGCT CCCACTTCAA AGCTTCTCAC 
CCCGTAGTGG ATCTTAAAGC ATTTCCAAAA GATAACCTGC TCTGGGTAGA ATGGACACCG 
CCATCTAAAC CTGTGAACAA ATACATACTA GAGTGGTGTG TGTTGTCAGA GAACTCACCC 
TGCATCCCAG ACTGGCAGCA AGAAGATGGC ACTGTGAATC GGACCCACTT AAGAGGAAGC 
CTACTGGAGA GCAAGTGCTA TCTGATCACA GTAACCCCAG TGTTTCCCGG TGGGCCTGGA 
AGCCCTGAGT CCATGAAGGC GTACCTCAAA CAAGCAGCTC CTTCTAAAGG ACCGACTGTT 
CGGACAAAGA AAGTGGGGAA AAATGAAGCT GTCTTAGAGT GGGACCATCT TCCTGTTGAT 
GTCCAGAACG GATTCATTAG AAACTACTCC ATATCTTATA GAACCAGTGT TGGAAAAGAA 
ATGGTTGTGC GTGTGGATTC TTCTCACACA GAATACACAC TGTCCTCTTT GAGTAGCGAT 
ACACTGTACA TGGTCCACAT GGCAGCATAC ACAGAAGAAG GTGGGAAGGA TGGGCCGGAA 
TTCACTTTTA CAACACTAAA GTTTGCTCAA GGAGAAATCG AAGCCATAGT CGTGCCTGTG 
TGCTTAGCTT TCCTCCTGAC AACGCTGCTG GGAGTCTTGT TCTGCTTTAA TAAACGAGAC 
CTAATTAAAA AACACATCTG GCCGAATGTC CCAGATCCTT CAAAGAGTCA TATTGCCCAG 
TGGTCACCTC ACACCCCCCC AAGGCACAAT TTTAACTCCA AAGATCAGAT GTACTCAGAT 
GCCAATTTCA CTGACGTAAG CGTTGTGGAA ATAGAAGCAA ACAACAAAAA GCCTTGTCCA 
GATGACCTGA AATCCTTGGA CCTGTTCAAG AAGGAGAAAA TAAGTACAGA AGGGCACAGC 
AGTGGCATTG GGGGGTCCTC GTGCATGTCC TCTTCTAGGC CCAGCATCTC CAGCAGTGAG 
GAGAACGAGT CTGCTCAGAG CACCGCAAGC ACGGTGCAGT ACTCCACCGT GGTGCACAGC 
GGCTACAGGC ACCAGGTGCC GTCAGTGCAA GTGTTCTCAA GGTCTGAGTC CACCCAGCCC 
CTGCTAGACT CCGAGGAGCG GCCAGAGGAC CTGCAGCTGG TGGATAGTGT GGACAGCGGT 
GACGAGATCT TACCCAGGCA ACAGTATTTC AAACAAAGCT GCAGTCAGCC TGGAGCCAGT 
CCAGATGTTT CACACTTCGA AAGGTCAAGC CAGGTTCCGT CAGGCAGTGA GGAGGATTTT 
GTCAGACTGA AACAGCAGCA GGTTTCAGAT CACATTTCAG AGCCCTATGG CTCCGAGCAA 
CGGAGGCTGT TTCAGGAAGG TTCTGTGGCA GATGCTCTTG GCACAGGGAC TGATGGACAG 
ATAGAGAGAT TCGAATCTGT TGGAATGGAG ACAGCGATGG ATGAAGACAT TTCCAAAAGT 
TACTTGCCAC AGACTGTAAG ACAAGGTGGC TACATGCCAC AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006231990.1
CDS	229..3033
Translation	MPYQFLGLCIGSIPCKMSALRIWLMQALLIFLTTESIGQLVEPCGYIYPEFPVVQRGSNFTATCVLKEKCLQVYSVNATYIVWKTNHVAVPKEQVTVINRTASSVTFTDVVFQNVQLTCNILSFGQIEQNVYGITILSGYPPDIPTNLSCIVNEGKNMLCQWDPGRETYLETNYTLKSEWATEKFPDCRTKHGTSSCMMGYTPIYFVNIEVWVEAENALGNVSSEPINFDPVDKVKPSPPHNLSVTNSEELSSILKLAWVNSGLDSILRLKSDIQYRTKDASTWIQVPLEDTVSPRTSFTVQDLKPFTEYVFRIRSIKENGKGYWSDWSEEASGTTYEDRPSKAPSFWYKVNANHPQEYRSARLIWKTLPLSEANGKILDYEVVLTQSKSVSQTYTVNGTELIVNLTNNRYVASLAARNVVGKSPATVLTIPGSHFKASHPVVDLKAFPKDNLLWVEWTPPSKPVNKYILEWCVLSENSPCIPDWQQEDGTVNRTHLRGSLLESKCYLITVTPVFPGGPGSPESMKAYLKQAAPSKGPTVRTKKVGKNEAVLEWDHLPVDVQNGFIRNYSISYRTSVGKEMVVRVDSSHTEYTLSSLSSDTLYMVHMAAYTEEGGKDGPEFTFTTLKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDANFTDVSVVEIEANNKKPCPDDLKSLDLFKKEKISTEGHSSGIGGSSCMSSSRPSISSSEENESAQSTASTVQYSTVVHSGYRHQVPSVQVFSRSESTQPLLDSEERPEDLQLVDSVDSGDEILPRQQYFKQSCSQPGASPDVSHFERSSQVPSGSEEDFVRLKQQQVSDHISEPYGSEQRRLFQEGSVADALGTGTDGQIERFESVGMETAMDEDISKSYLPQTVRQGGYMPQ

Target ORF information:

RefSeq Version	XM_006231928.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus interleukin 6 signal transducer (Il6st), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006231928.3

ORF Insert Sequence:

ATGCCTTATC AGTTCTTAGG TTTGTGTATT GGGAGCATCC CTTGCAAGAT GTCCGCACTA 
AGGATCTGGC TAATGCAAGC TTTGCTTATT TTCCTCACTA CTGAGTCTAT AGGTCAACTT 
GTGGAACCAT GTGGTTATAT CTACCCTGAG TTTCCAGTTG TCCAGCGTGG CTCTAACTTC 
ACTGCCACTT GTGTGCTAAA GGAGAAGTGT CTGCAGGTGT ACTCCGTGAA TGCCACTTAC 
ATCGTGTGGA AGACAAACCA TGTTGCCGTT CCTAAGGAGC AGGTCACAGT CATCAACAGA 
ACGGCATCCA GTGTCACATT CACAGACGTG GTCTTTCAGA ACGTCCAGCT CACCTGCAAT 
ATCCTGTCAT TTGGACAGAT CGAGCAGAAT GTGTATGGAA TCACCATACT TTCAGGCTAT 
CCTCCAGATA TACCTACAAA TTTGAGTTGC ATTGTGAATG AGGGGAAGAA CATGCTGTGT 
CAGTGGGACC CAGGAAGGGA GACATACCTT GAAACAAACT ACACTTTGAA GTCAGAGTGG 
GCAACAGAGA AGTTTCCTGA TTGTCGAACA AAGCATGGCA CGAGCTCCTG CATGATGGGC 
TATACCCCCA TCTATTTTGT CAACATCGAG GTCTGGGTGG AGGCCGAGAA TGCCCTTGGG 
AATGTCTCCT CAGAGCCTAT CAATTTTGAC CCCGTGGATA AAGTGAAACC CAGCCCACCT 
CATAATTTGT CAGTGACCAA CTCAGAAGAA TTATCCAGTA TATTAAAACT AGCATGGGTC 
AATTCAGGTT TGGACAGTAT TTTAAGGCTG AAGTCGGACA TCCAATATAG GACCAAAGAT 
GCCTCAACTT GGATTCAGGT CCCTCTTGAA GATACAGTGT CTCCCCGGAC TTCGTTCACT 
GTTCAGGATC TCAAGCCTTT TACAGAATAT GTGTTTAGGA TTCGGTCCAT TAAGGAGAAT 
GGGAAGGGCT ACTGGAGTGA CTGGAGTGAG GAGGCGAGCG GGACCACATA TGAAGACAGA 
CCATCCAAAG CGCCAAGTTT CTGGTATAAG GTAAATGCAA ACCATCCACA GGAGTATAGG 
TCTGCACGGC TCATATGGAA GACATTGCCC CTTTCTGAAG CCAATGGGAA GATCTTGGAT 
TATGAAGTGG TTCTTACACA GTCCAAGTCA GTTTCGCAAA CTTACACAGT TAACGGCACA 
GAGTTGATAG TAAACCTCAC CAATAACCGC TATGTAGCGT CTCTAGCAGC AAGAAATGTG 
GTCGGCAAGT CCCCTGCAAC CGTCCTCACC ATCCCCGGCT CCCACTTCAA AGCTTCTCAC 
CCCGTAGTGG ATCTTAAAGC ATTTCCAAAA GATAACCTGC TCTGGGTAGA ATGGACACCG 
CCATCTAAAC CTGTGAACAA ATACATACTA GAGTGGTGTG TGTTGTCAGA GAACTCACCC 
TGCATCCCAG ACTGGCAGCA AGAAGATGGC ACTGTGAATC GGACCCACTT AAGAGGAAGC 
CTACTGGAGA GCAAGTGCTA TCTGATCACA GTAACCCCAG TGTTTCCCGG TGGGCCTGGA 
AGCCCTGAGT CCATGAAGGC GTACCTCAAA CAAGCAGCTC CTTCTAAAGG ACCGACTGTT 
CGGACAAAGA AAGTGGGGAA AAATGAAGCT GTCTTAGAGT GGGACCATCT TCCTGTTGAT 
GTCCAGAACG GATTCATTAG AAACTACTCC ATATCTTATA GAACCAGTGT TGGAAAAGAA 
ATGGTTGTGC GTGTGGATTC TTCTCACACA GAATACACAC TGTCCTCTTT GAGTAGCGAT 
ACACTGTACA TGGTCCACAT GGCAGCATAC ACAGAAGAAG GTGGGAAGGA TGGGCCGGAA 
TTCACTTTTA CAACACTAAA GTTTGCTCAA GGAGAAATCG AAGCCATAGT CGTGCCTGTG 
TGCTTAGCTT TCCTCCTGAC AACGCTGCTG GGAGTCTTGT TCTGCTTTAA TAAACGAGAC 
CTAATTAAAA AACACATCTG GCCGAATGTC CCAGATCCTT CAAAGAGTCA TATTGCCCAG 
TGGTCACCTC ACACCCCCCC AAGGCACAAT TTTAACTCCA AAGATCAGAT GTACTCAGAT 
GCCAATTTCA CTGACGTAAG CGTTGTGGAA ATAGAAGCAA ACAACAAAAA GCCTTGTCCA 
GATGACCTGA AATCCTTGGA CCTGTTCAAG AAGGAGAAAA TAAGTACAGA AGGGCACAGC 
AGTGGCATTG GGGGGTCCTC GTGCATGTCC TCTTCTAGGC CCAGCATCTC CAGCAGTGAG 
GAGAACGAGT CTGCTCAGAG CACCGCAAGC ACGGTGCAGT ACTCCACCGT GGTGCACAGC 
GGCTACAGGC ACCAGGTGCC GTCAGTGCAA GTGTTCTCAA GGTCTGAGTC CACCCAGCCC 
CTGCTAGACT CCGAGGAGCG GCCAGAGGAC CTGCAGCTGG TGGATAGTGT GGACAGCGGT 
GACGAGATCT TACCCAGGCA ACAGTATTTC AAACAAAGCT GCAGTCAGCC TGGAGCCAGT 
CCAGATGTTT CACACTTCGA AAGGTCAAGC CAGGTTCCGT CAGGCAGTGA GGAGGATTTT 
GTCAGACTGA AACAGCAGCA GGTTTCAGAT CACATTTCAG AGCCCTATGG CTCCGAGCAA 
CGGAGGCTGT TTCAGGAAGG TTCTGTGGCA GATGCTCTTG GCACAGGGAC TGATGGACAG 
ATAGAGAGAT TCGAATCTGT TGGAATGGAG ACAGCGATGG ATGAAGACAT TTCCAAAAGT 
TACTTGCCAC AGACTGTAAG ACAAGGTGGC TACATGCCAC AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Pulmonary instillation of MWCNT increases lung permeability, decreases gp130 expression in the lungs, and initiates cardiovascular IL-6 transsignaling.
American journal of physiology. Lung cellular and molecular physiology310(2)L142-54(2016 Jan)
Thompson LC,Holland NA,Snyder RJ,Luo B,Becak DP,Odom JT,Harrison BS,Brown JM,Gowdy KM,Wingard CJ

Identification of Spinal Cord MicroRNA and Gene Signatures in a Model of Chronic Stress-Induced Visceral Hyperalgesia in Rat.
PloS one10(7)e0130938(2015)
Bradesi S,Karagiannides I,Bakirtzi K,Joshi SM,Koukos G,Iliopoulos D,Pothoulakis C,Mayer EA

The inhibition of N-glycosylation of glycoprotein 130 molecule abolishes STAT3 activation by IL-6 family cytokines in cultured cardiac myocytes.
PloS one9(10)e111097(2014)
Matsuo R,Morihara H,Mohri T,Murasawa S,Takewaki K,Nakayama H,Maeda M,Fujio Y

Biochemical and functional analyses of gp130 mutants unveil JAK1 as a novel therapeutic target in human inflammatory hepatocellular adenoma.
Oncoimmunology2(12)e27090(2013 Dec)
Poussin K,Pilati C,Couchy G,Calderaro J,Bioulac-Sage P,Bacq Y,Paradis V,Leteurtre E,Sturm N,Ramos J,Guettier C,Bardier-Dupas A,Boulai A,Wendum D,Selves J,Izard T,Nault JC,Zucman-Rossi J

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Il6st cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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