Rhox5 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rhox5
Entrez Gene ID	24631
Full Name	Rhox homeobox family member 5
Synonyms	Pem
General protein information	Preferred Names Rhox homeobox family member 5 Names homeobox protein Rhox5 Homeobox gene Pem homeobox protein Pem placenta and embryonic expression protein placentae and embryos oncofetal reproductive homeobox 5 reproductive homeobox on chromosome X 5
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: X Map Location: Xq35
Summary	homeodomain-containing protein; may regulate androgen-dependent events in the epididymis [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006257475.1	XP_006257537.1	homeobox protein Rhox5 isoform X1
XM_006257473.3	XP_006257535.1	homeobox protein Rhox5 isoform X1
NM_022175.1	NP_071511.1	homeobox protein Rhox5
XM_008773400.2	XP_008771622.1	homeobox protein Rhox5 isoform X1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Rhox5	NP_032844.2
Rattus norvegicus (Norway rat)	Rhox5	NP_071511.1

Gene Ontology
Bibliography

Related articles in PubMed

The Rhox5 homeobox gene regulates the region-specific expression of its paralogs in the rodent epididymis.
MacLean JA 2nd, Hayashi K, Turner TT, Wilkinson MF
Biology of reproduction86(6)189(2012 Jun)

DNA demethylation-dependent AR recruitment and GATA factors drive Rhox5 homeobox gene transcription in the epididymis.
Bhardwaj A, Song HW, Beildeck M, Kerkhofs S, Castoro R, Shanker S, De Gendt K, Suzuki K, Claessens F, Issa JP, Orgebin-Crist MC, Wilkinson MF
Molecular endocrinology (Baltimore, Md.)26(4)538-49(2012 Apr)

Regulation of the Rhox5 homeobox gene in primary granulosa cells: preovulatory expression and dependence on SP1/SP3 and GABP.
MacLean JA 2nd, Rao MK, Doyle KM, Richards JS, Wilkinson MF
Biology of reproduction73(6)1126-34(2005 Dec)

A highly active homeobox gene promoter regulated by Ets and Sp1 family members in normal granulosa cells and diverse tumor cell types.
Rao MK, Maiti S, Ananthaswamy HN, Wilkinson MF
The Journal of biological chemistry277(29)26036-45(2002 Jul)

The Pem homeobox gene: rapid evolution of the homeodomain, X chromosomal localization, and expression in reproductive tissue.
Maiti S, Doskow J, Sutton K, Nhim RP, Lawlor DA, Levan K, Lindsey JS, Wilkinson MF
Genomics34(3)304-16(1996 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

regulates the expression of other Rhox genes in the epididymis
Title: The Rhox5 homeobox gene regulates the region-specific expression of its paralogs in the rodent epididymis.

GATA factors collaborate to dictate the unique developmental and region-specific expression pattern of the RHOX5 homeobox transcription factor in the caput epididymis.
Title: DNA demethylation-dependent AR recruitment and GATA factors drive Rhox5 homeobox gene transcription in the epididymis.

expression in the ovary is governed by the distal promoter and is expressed at least as early as Day 5 postpartum. mRNA levels are regulated during the ovarian cycle, peaking before ovulation
Title: Regulation of the Rhox5 homeobox gene in primary granulosa cells: preovulatory expression and dependence on SP1/SP3 and GABP.

Pem promoter may be a useful model system to understand the molecular mechanism by which a tissue-specific promoter can be corrupted in tumor cells
Title: A highly active homeobox gene promoter regulated by Ets and Sp1 family members in normal granulosa cells and diverse tumor cell types.

The following Rhox5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rhox5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa42694	NM_022175.1 Latest version!	Rattus norvegicus Rhox homeobox family member 5 (Rhox5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa40204	XM_006257475.1 Latest version!	Rattus norvegicus reproductive homeobox 5 (Rhox5), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa40204	XM_008773400.2 Latest version!	Rattus norvegicus reproductive homeobox 5 (Rhox5), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa40204	XM_006257473.3 Latest version!	Rattus norvegicus reproductive homeobox 5 (Rhox5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rhox5 ( NM_022175.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_071511.1 Rattus norvegicus Rhox homeobox family member 5 (Rhox5), mRNA.

Price & Availability↑

CloneID	ORa42694
Clone ID Related Accession (Same CDS sequence)	NM_022175.1
Accession Version	NM_022175.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 636bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Rattus norvegicus(Norway rat)
Product	homeobox protein Rhox5
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U52034.1. ##Evidence-Data-START## Transcript exon combination :: DQ058653.1 [ECO:0000332] ##Evidence-Data-END##

ATGGAGGCTC AAGGCTCTAG CCATGATATC AGCCGCTTAC TCTGCCTGGG AGTCAAGGAA 
GACTCGGAAG AACAGCATGG TCAGTACCTG GGTGATGTGA AAGCAGAGGC TTTCTTTCAG 
GCTGGAGAGG GGAGAGACGA GAAAGGTGCA CAGGGTCAGC CTGGAGAGGG AGCAGTGGGA 
ACAGAAGGCG AAGGAGAAGA ATTAAATGGA GGAGAAGGCC ACTTTGGTCC TGGTGTTCCA 
GGTCCTGTGG GTGAGGGGGA CAAGGATGGT GGCACCAGAG CTAGTGGCAT GGAGGAGGAG 
CAACATGAGC CCGTTGCCGA GGGCACTGAG AGTGTCAAGT CTGAGGATAA GCAGATGCCA 
CTCCGCCGCC CTGGGTCCAC CCAGCGGCGG CTGGCGGAAT TGGAGCGCAT TTTGCTAAGC 
AGTGGTTCCT CCAGTGGCGG GAGGAGCTTG ATAGATGGAT GGATATCAGT GTGTCCAGAG 
TGCAGGAATT GGTTTAAGAT TAGGAGGGCT GCATACAGAA GAAATAGGAG GCGGAGAACA 
CCAATCCCTG AACATTTTAG AGCAACATCT GGGTGCCCTG CTTGTCTTGG AGCAAGATGG 
GGAGTAAGAT GTCCTTTTGC AACACCGAGA TTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071511.1
CDS	1..636
Translation	MEAQGSSHDISRLLCLGVKEDSEEQHGQYLGDVKAEAFFQAGEGRDEKGAQGQPGEGAVGTEGEGEELNGGEGHFGPGVPGPVGEGDKDGGTRASGMEEEQHEPVAEGTESVKSEDKQMPLRRPGSTQRRLAELERILLSSGSSSGGRSLIDGWISVCPECRNWFKIRRAAYRRNRRRRTPIPEHFRATSGCPACLGARWGVRCPFATPRF

Target ORF information:

RefSeq Version	NM_022175.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Rhox homeobox family member 5 (Rhox5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022175.1

ORF Insert Sequence:

ATGGAGGCTC AAGGCTCTAG CCATGATATC AGCCGCTTAC TCTGCCTGGG AGTCAAGGAA 
GACTCGGAAG AACAGCATGG TCAGTACCTG GGTGATGTGA AAGCAGAGGC TTTCTTTCAG 
GCTGGAGAGG GGAGAGACGA GAAAGGTGCA CAGGGTCAGC CTGGAGAGGG AGCAGTGGGA 
ACAGAAGGCG AAGGAGAAGA ATTAAATGGA GGAGAAGGCC ACTTTGGTCC TGGTGTTCCA 
GGTCCTGTGG GTGAGGGGGA CAAGGATGGT GGCACCAGAG CTAGTGGCAT GGAGGAGGAG 
CAACATGAGC CCGTTGCCGA GGGCACTGAG AGTGTCAAGT CTGAGGATAA GCAGATGCCA 
CTCCGCCGCC CTGGGTCCAC CCAGCGGCGG CTGGCGGAAT TGGAGCGCAT TTTGCTAAGC 
AGTGGTTCCT CCAGTGGCGG GAGGAGCTTG ATAGATGGAT GGATATCAGT GTGTCCAGAG 
TGCAGGAATT GGTTTAAGAT TAGGAGGGCT GCATACAGAA GAAATAGGAG GCGGAGAACA 
CCAATCCCTG AACATTTTAG AGCAACATCT GGGTGCCCTG CTTGTCTTGG AGCAAGATGG 
GGAGTAAGAT GTCCTTTTGC AACACCGAGA TTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rhox5 ( XM_006257475.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006257537.1 Rattus norvegicus reproductive homeobox 5 (Rhox5), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa40204
Clone ID Related Accession (Same CDS sequence)	XM_006257475.1 , XM_006257473.3 , XM_008773400.2
Accession Version	XM_006257475.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 627bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	homeobox protein Rhox5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGCTC AAGGCTCTAG CCATGATATC AGCCGCTTAC TCTGCCTGGG AGTCAAGGAA 
GACTCGGAAG AACAGCATGA TGTGAAAGCA GAGGCTTTCT TTCAGGCTGG AGAGGGGAGA 
GACGAGAAAG GTGCACAGGG TCAGCCTGGA GAGGGAGCAG TGGGAACAGA AGGCGAAGGA 
GAAGAATTAA ATGGAGGAGA AGGCCACTTT GGTCCTGGTG TTCCAGGTCC TGTGGGTGAG 
GGGGACAAGG ATGGTGGCAC CAGAGCTAGT GGCATGGAGG AGGAGCAACA TGAGCCCGTT 
GCCGAGGGCA CTGAGAGTGT CAAGTCTGAG GATAAGCAGA TGCCACTCCG CCGCCCTGGG 
TCCACCCAGC GGCGGCTGGC GGAATTGGAG CGCATTTTGC TAAGCAGTGG TTCCTCCAGT 
GGCCCAACAT GGGAGGAGCT TGATAGATGG ATGGATATCA GTGTGTCCAG AGTGCAGAAT 
TGGTTTAAGA TTAGGAGGGC TGCATACAGA AGAAATAGGA GGCGGAGAAC ACCAATCCCT 
GAACATTTTA GAGCAACATC TGGGTGCCCT GCTTGTCTTG GAGCAAGATG GGGAGTAAGA 
TGTCCTTTTG CAACACCGAG ATTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006257537.1
CDS	209..835
Translation	MEAQGSSHDISRLLCLGVKEDSEEQHDVKAEAFFQAGEGRDEKGAQGQPGEGAVGTEGEGEELNGGEGHFGPGVPGPVGEGDKDGGTRASGMEEEQHEPVAEGTESVKSEDKQMPLRRPGSTQRRLAELERILLSSGSSSGPTWEELDRWMDISVSRVQNWFKIRRAAYRRNRRRRTPIPEHFRATSGCPACLGARWGVRCPFATPRF

Target ORF information:

RefSeq Version	XM_006257475.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus reproductive homeobox 5 (Rhox5), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006257475.1

ORF Insert Sequence:

ATGGAGGCTC AAGGCTCTAG CCATGATATC AGCCGCTTAC TCTGCCTGGG AGTCAAGGAA 
GACTCGGAAG AACAGCATGA TGTGAAAGCA GAGGCTTTCT TTCAGGCTGG AGAGGGGAGA 
GACGAGAAAG GTGCACAGGG TCAGCCTGGA GAGGGAGCAG TGGGAACAGA AGGCGAAGGA 
GAAGAATTAA ATGGAGGAGA AGGCCACTTT GGTCCTGGTG TTCCAGGTCC TGTGGGTGAG 
GGGGACAAGG ATGGTGGCAC CAGAGCTAGT GGCATGGAGG AGGAGCAACA TGAGCCCGTT 
GCCGAGGGCA CTGAGAGTGT CAAGTCTGAG GATAAGCAGA TGCCACTCCG CCGCCCTGGG 
TCCACCCAGC GGCGGCTGGC GGAATTGGAG CGCATTTTGC TAAGCAGTGG TTCCTCCAGT 
GGCCCAACAT GGGAGGAGCT TGATAGATGG ATGGATATCA GTGTGTCCAG AGTGCAGAAT 
TGGTTTAAGA TTAGGAGGGC TGCATACAGA AGAAATAGGA GGCGGAGAAC ACCAATCCCT 
GAACATTTTA GAGCAACATC TGGGTGCCCT GCTTGTCTTG GAGCAAGATG GGGAGTAAGA 
TGTCCTTTTG CAACACCGAG ATTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rhox5 ( XM_006257473.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006257535.1 Rattus norvegicus reproductive homeobox 5 (Rhox5), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa40204
Clone ID Related Accession (Same CDS sequence)	XM_006257475.1 , XM_006257473.3 , XM_008773400.2
Accession Version	XM_006257473.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 627bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	homeobox protein Rhox5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006257473.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGCTC AAGGCTCTAG CCATGATATC AGCCGCTTAC TCTGCCTGGG AGTCAAGGAA 
GACTCGGAAG AACAGCATGA TGTGAAAGCA GAGGCTTTCT TTCAGGCTGG AGAGGGGAGA 
GACGAGAAAG GTGCACAGGG TCAGCCTGGA GAGGGAGCAG TGGGAACAGA AGGCGAAGGA 
GAAGAATTAA ATGGAGGAGA AGGCCACTTT GGTCCTGGTG TTCCAGGTCC TGTGGGTGAG 
GGGGACAAGG ATGGTGGCAC CAGAGCTAGT GGCATGGAGG AGGAGCAACA TGAGCCCGTT 
GCCGAGGGCA CTGAGAGTGT CAAGTCTGAG GATAAGCAGA TGCCACTCCG CCGCCCTGGG 
TCCACCCAGC GGCGGCTGGC GGAATTGGAG CGCATTTTGC TAAGCAGTGG TTCCTCCAGT 
GGCCCAACAT GGGAGGAGCT TGATAGATGG ATGGATATCA GTGTGTCCAG AGTGCAGAAT 
TGGTTTAAGA TTAGGAGGGC TGCATACAGA AGAAATAGGA GGCGGAGAAC ACCAATCCCT 
GAACATTTTA GAGCAACATC TGGGTGCCCT GCTTGTCTTG GAGCAAGATG GGGAGTAAGA 
TGTCCTTTTG CAACACCGAG ATTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006257535.1
CDS	103..729
Translation	MEAQGSSHDISRLLCLGVKEDSEEQHDVKAEAFFQAGEGRDEKGAQGQPGEGAVGTEGEGEELNGGEGHFGPGVPGPVGEGDKDGGTRASGMEEEQHEPVAEGTESVKSEDKQMPLRRPGSTQRRLAELERILLSSGSSSGPTWEELDRWMDISVSRVQNWFKIRRAAYRRNRRRRTPIPEHFRATSGCPACLGARWGVRCPFATPRF

Target ORF information:

RefSeq Version	XM_006257473.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus reproductive homeobox 5 (Rhox5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006257473.3

ORF Insert Sequence:

ATGGAGGCTC AAGGCTCTAG CCATGATATC AGCCGCTTAC TCTGCCTGGG AGTCAAGGAA 
GACTCGGAAG AACAGCATGA TGTGAAAGCA GAGGCTTTCT TTCAGGCTGG AGAGGGGAGA 
GACGAGAAAG GTGCACAGGG TCAGCCTGGA GAGGGAGCAG TGGGAACAGA AGGCGAAGGA 
GAAGAATTAA ATGGAGGAGA AGGCCACTTT GGTCCTGGTG TTCCAGGTCC TGTGGGTGAG 
GGGGACAAGG ATGGTGGCAC CAGAGCTAGT GGCATGGAGG AGGAGCAACA TGAGCCCGTT 
GCCGAGGGCA CTGAGAGTGT CAAGTCTGAG GATAAGCAGA TGCCACTCCG CCGCCCTGGG 
TCCACCCAGC GGCGGCTGGC GGAATTGGAG CGCATTTTGC TAAGCAGTGG TTCCTCCAGT 
GGCCCAACAT GGGAGGAGCT TGATAGATGG ATGGATATCA GTGTGTCCAG AGTGCAGAAT 
TGGTTTAAGA TTAGGAGGGC TGCATACAGA AGAAATAGGA GGCGGAGAAC ACCAATCCCT 
GAACATTTTA GAGCAACATC TGGGTGCCCT GCTTGTCTTG GAGCAAGATG GGGAGTAAGA 
TGTCCTTTTG CAACACCGAG ATTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rhox5 ( XM_008773400.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008771622.1 Rattus norvegicus reproductive homeobox 5 (Rhox5), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa40204
Clone ID Related Accession (Same CDS sequence)	XM_006257475.1 , XM_006257473.3 , XM_008773400.2
Accession Version	XM_008773400.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 627bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	homeobox protein Rhox5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008773400.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGCTC AAGGCTCTAG CCATGATATC AGCCGCTTAC TCTGCCTGGG AGTCAAGGAA 
GACTCGGAAG AACAGCATGA TGTGAAAGCA GAGGCTTTCT TTCAGGCTGG AGAGGGGAGA 
GACGAGAAAG GTGCACAGGG TCAGCCTGGA GAGGGAGCAG TGGGAACAGA AGGCGAAGGA 
GAAGAATTAA ATGGAGGAGA AGGCCACTTT GGTCCTGGTG TTCCAGGTCC TGTGGGTGAG 
GGGGACAAGG ATGGTGGCAC CAGAGCTAGT GGCATGGAGG AGGAGCAACA TGAGCCCGTT 
GCCGAGGGCA CTGAGAGTGT CAAGTCTGAG GATAAGCAGA TGCCACTCCG CCGCCCTGGG 
TCCACCCAGC GGCGGCTGGC GGAATTGGAG CGCATTTTGC TAAGCAGTGG TTCCTCCAGT 
GGCCCAACAT GGGAGGAGCT TGATAGATGG ATGGATATCA GTGTGTCCAG AGTGCAGAAT 
TGGTTTAAGA TTAGGAGGGC TGCATACAGA AGAAATAGGA GGCGGAGAAC ACCAATCCCT 
GAACATTTTA GAGCAACATC TGGGTGCCCT GCTTGTCTTG GAGCAAGATG GGGAGTAAGA 
TGTCCTTTTG CAACACCGAG ATTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008771622.1
CDS	366..992
Translation	MEAQGSSHDISRLLCLGVKEDSEEQHDVKAEAFFQAGEGRDEKGAQGQPGEGAVGTEGEGEELNGGEGHFGPGVPGPVGEGDKDGGTRASGMEEEQHEPVAEGTESVKSEDKQMPLRRPGSTQRRLAELERILLSSGSSSGPTWEELDRWMDISVSRVQNWFKIRRAAYRRNRRRRTPIPEHFRATSGCPACLGARWGVRCPFATPRF

Target ORF information:

RefSeq Version	XM_008773400.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus reproductive homeobox 5 (Rhox5), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008773400.2

ORF Insert Sequence:

ATGGAGGCTC AAGGCTCTAG CCATGATATC AGCCGCTTAC TCTGCCTGGG AGTCAAGGAA 
GACTCGGAAG AACAGCATGA TGTGAAAGCA GAGGCTTTCT TTCAGGCTGG AGAGGGGAGA 
GACGAGAAAG GTGCACAGGG TCAGCCTGGA GAGGGAGCAG TGGGAACAGA AGGCGAAGGA 
GAAGAATTAA ATGGAGGAGA AGGCCACTTT GGTCCTGGTG TTCCAGGTCC TGTGGGTGAG 
GGGGACAAGG ATGGTGGCAC CAGAGCTAGT GGCATGGAGG AGGAGCAACA TGAGCCCGTT 
GCCGAGGGCA CTGAGAGTGT CAAGTCTGAG GATAAGCAGA TGCCACTCCG CCGCCCTGGG 
TCCACCCAGC GGCGGCTGGC GGAATTGGAG CGCATTTTGC TAAGCAGTGG TTCCTCCAGT 
GGCCCAACAT GGGAGGAGCT TGATAGATGG ATGGATATCA GTGTGTCCAG AGTGCAGAAT 
TGGTTTAAGA TTAGGAGGGC TGCATACAGA AGAAATAGGA GGCGGAGAAC ACCAATCCCT 
GAACATTTTA GAGCAACATC TGGGTGCCCT GCTTGTCTTG GAGCAAGATG GGGAGTAAGA 
TGTCCTTTTG CAACACCGAG ATTTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The Rhox5 homeobox gene regulates the region-specific expression of its paralogs in the rodent epididymis.
Biology of reproduction86(6)189(2012 Jun)
MacLean JA 2nd,Hayashi K,Turner TT,Wilkinson MF

DNA demethylation-dependent AR recruitment and GATA factors drive Rhox5 homeobox gene transcription in the epididymis.
Molecular endocrinology (Baltimore, Md.)26(4)538-49(2012 Apr)
Bhardwaj A,Song HW,Beildeck M,Kerkhofs S,Castoro R,Shanker S,De Gendt K,Suzuki K,Claessens F,Issa JP,Orgebin-Crist MC,Wilkinson MF

Regulation of the Rhox5 homeobox gene in primary granulosa cells: preovulatory expression and dependence on SP1/SP3 and GABP.
Biology of reproduction73(6)1126-34(2005 Dec)
MacLean JA 2nd,Rao MK,Doyle KM,Richards JS,Wilkinson MF

A highly active homeobox gene promoter regulated by Ets and Sp1 family members in normal granulosa cells and diverse tumor cell types.
The Journal of biological chemistry277(29)26036-45(2002 Jul)
Rao MK,Maiti S,Ananthaswamy HN,Wilkinson MF

The Pem homeobox gene: rapid evolution of the homeodomain, X chromosomal localization, and expression in reproductive tissue.
Genomics34(3)304-16(1996 Jun)
Maiti S,Doskow J,Sutton K,Nhim RP,Lawlor DA,Levan K,Lindsey JS,Wilkinson MF