Mos cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mos
Entrez Gene ID	24559
Full Name	MOS proto-oncogene, serine/threonine kinase
General protein information	Preferred Names MOS proto-oncogene, serine/threonine kinase Names proto-oncogene serine/threonine-protein kinase mos Moloney murine sarcoma viral (v-mos) oncogene homolog Moloney sarcoma oncogene c-mos oocyte maturation factor mos proto-oncogene c-Mos v-mos moloney murine sarcoma viral oncogene homolog
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q12
Summary	phosphorylates and activates Map2k1; may play a role in meiotic division of spermatocytes and oocytes [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_020102.4	NP_064487.3	proto-oncogene serine/threonine-protein kinase mos

Pathways from BioSystems

Homologies

Bos taurus (cattle)	MOS	XP_002692700.1
Mus musculus (house mouse)	Mos	NP_064405.2
Rattus norvegicus (Norway rat)	Mos	NP_064487.3
Xenopus tropicalis (tropical clawed frog)	LOC100489962	XP_004915249.1
Homo sapiens (human)	MOS	NP_005363.1
	MOS	XP_001087400.2
Canis lupus familiaris (dog)	MOS	XP_544088.4
Gallus gallus (chicken)	MOS	NP_001026687.1
Pan troglodytes (chimpanzee)	MOS	XP_528144.2
Danio rerio (zebrafish)	mos	NP_991143.1

Gene Ontology
Bibliography

Related articles in PubMed

Mouse Emi2 as a distinctive regulatory hub in second meiotic metaphase.
Suzuki T, Suzuki E, Yoshida N, Kubo A, Li H, Okuda E, Amanai M, Perry AC
Development (Cambridge, England)137(19)3281-91(2010 Oct)

Insufficient amount of Cdc2 and continuous activation of Wee1 B are the cause of meiotic failure in porcine growing oocytes.
Nishimura T, Shimaoka T, Kano K, Naito K
The Journal of reproduction and development55(5)553-7(2009 Oct)

Cytostatic factor proteins are present in male meiotic cells and beta-nerve growth factor increases mos levels in rat late spermatocytes.
Perrard MH, Chassaing E, Montillet G, Sabido O, Durand P
PloS one4(10)e7237(2009 Oct)

Analyses of mitogen-activated protein kinase function in the maturation of porcine oocytes.
Ohashi S, Naito K, Sugiura K, Iwamori N, Goto S, Naruoka H, Tojo H
Biology of reproduction68(2)604-9(2003 Feb)

Successful inactivation of endogenous Oct-3/4 and c-mos genes in mouse preimplantation embryos and oocytes using short interfering RNAs.
Kim MH, Yuan X, Okumura S, Ishikawa F
Biochemical and biophysical research communications296(5)1372-7(2002 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

NGF, by enhancing Mos in late spermatocytes, is one of the intra-testicular factors which adjusts the number of round spermatids that can be supported by Sertoli cells
Title: Cytostatic factor proteins are present in male meiotic cells and beta-nerve growth factor increases mos levels in rat late spermatocytes.

cAMP-Dependent PKA negatively regulates polyadenylation of c-mos mRNA in rat oocytes
Title: cAMP-Dependent PKA negatively regulates polyadenylation of c-mos mRNA in rat oocytes.

Definitive expression of c-mos in late meiotic prophase leads to phosphorylation of a 34 kda protein in cultured rat spermatocytes
Title: Definitive expression of c-mos in late meiotic prophase leads to phosphorylation of a 34 kda protein in cultured rat spermatocytes.

The following Mos gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mos cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa39832	NM_020102.4 Latest version!	Rattus norvegicus MOS proto-oncogene, serine/threonine kinase (Mos), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mos ( NM_020102.4 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_064487.3 Rattus norvegicus MOS proto-oncogene, serine/threonine kinase (Mos), mRNA.

Price & Availability↑

CloneID	ORa39832
Clone ID Related Accession (Same CDS sequence)	NM_020102.4
Accession Version	NM_020102.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1029bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-16
Organism	Rattus norvegicus(Norway rat)
Product	proto-oncogene serine/threonine-protein kinase mos
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC129839.5. On Sep 20, 2014 this sequence version replaced NM_020102.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.

ATGCCTTCGC CTCTCATCCT GTGTCGCTAC CTCCCTCGCG AGCTGTCGCC AACGGTGGAC 
TCGAGGTCCT GCAGCAGCCC CTTGGTGGCC TCGAGGAAGG CGGGGAAGTT CCTGGGGGCC 
ACTCCTCCTC GGGCCCCGCG GCTGTCACGC CGGCTGGCCT GGTGCTTCAT AGACTGGGGA 
CAGGTATGCC TGCTGCATAG GCTGGGTTCT GGAGGGTTTG GCTCGGTGTA CAAAGCCACT 
TACCACGGTG TTCCTGTGGC CATCAAGCAA GTGAACAAGT GCACCAGGAA CCTACGTGCA 
TCCCAGCGGA GTTTCTGGGC TGAACTGAAC ATTGCAAGGC TGCACCACGA CAACATAGTC 
CGGGTTGTGG CTGCCAGCAC GCGCACGCCG GAAGGTTCCA ACAGCCTTGG TACCATAATC 
ATGGAGTTTG GGGGCAATGT GACTCTACAC CAAGTCATCT ACGGTGCCAC CCGCTCCCCA 
GAGCCTCTCA GCTGCAGAGA GCAACTGAGT TTGGGAAAGT GCCTCAAGTA TTCCCTAGAT 
ATTGTTAACG GCCTGCTTTT TCTCCACTCA CAAAGCATTT TGCACTTGGA CCTGAAGCCA 
GCGAACATTT TGATCAGTGA GAAGGACGTT TGTAAGATAA GTGACTTCGG CTGCTCCCAG 
AAGCTTCAGG ATCTGCGGTG CCGGCAGGCG TCCCTTCACC ACATCGGGGG CACGTACACG 
CACCAAGCTC CGGAGCTCCT GAAAGGAGAG ATCGCCACGC CCAAAGCCGA CATCTACTCT 
TTTGGCATCA CCCTGTGGCA GATGACCACC AGGGAGGTGC CTTACTCCGG CGAGCCTCAG 
TACGTGCAGT ACGCAGTGGT AGCCTACAAT CTGCGCCCGT CACTGGCAGG GGCGGTGTTC 
ACCGCCTCCC TGACTGGGAA GACGCTGCAG AACATCGTCC AGAGCTGCTG GGAGGCCCGC 
GCCCTGCAGA GGCCGGGTGC AGAACTGCTC CAGAAGGACC TGAAGGCTTT CCGAGGGGCA 
CTGGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_064487.3
CDS	171..1199
Translation	MPSPLILCRYLPRELSPTVDSRSCSSPLVASRKAGKFLGATPPRAPRLSRRLAWCFIDWGQVCLLHRLGSGGFGSVYKATYHGVPVAIKQVNKCTRNLRASQRSFWAELNIARLHHDNIVRVVAASTRTPEGSNSLGTIIMEFGGNVTLHQVIYGATRSPEPLSCREQLSLGKCLKYSLDIVNGLLFLHSQSILHLDLKPANILISEKDVCKISDFGCSQKLQDLRCRQASLHHIGGTYTHQAPELLKGEIATPKADIYSFGITLWQMTTREVPYSGEPQYVQYAVVAYNLRPSLAGAVFTASLTGKTLQNIVQSCWEARALQRPGAELLQKDLKAFRGALG

Target ORF information:

RefSeq Version	NM_020102.4
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus MOS proto-oncogene, serine/threonine kinase (Mos), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020102.4

ORF Insert Sequence:

ATGCCTTCGC CTCTCATCCT GTGTCGCTAC CTCCCTCGCG AGCTGTCGCC AACGGTGGAC 
TCGAGGTCCT GCAGCAGCCC CTTGGTGGCC TCGAGGAAGG CGGGGAAGTT CCTGGGGGCC 
ACTCCTCCTC GGGCCCCGCG GCTGTCACGC CGGCTGGCCT GGTGCTTCAT AGACTGGGGA 
CAGGTATGCC TGCTGCATAG GCTGGGTTCT GGAGGGTTTG GCTCGGTGTA CAAAGCCACT 
TACCACGGTG TTCCTGTGGC CATCAAGCAA GTGAACAAGT GCACCAGGAA CCTACGTGCA 
TCCCAGCGGA GTTTCTGGGC TGAACTGAAC ATTGCAAGGC TGCACCACGA CAACATAGTC 
CGGGTTGTGG CTGCCAGCAC GCGCACGCCG GAAGGTTCCA ACAGCCTTGG TACCATAATC 
ATGGAGTTTG GGGGCAATGT GACTCTACAC CAAGTCATCT ACGGTGCCAC CCGCTCCCCA 
GAGCCTCTCA GCTGCAGAGA GCAACTGAGT TTGGGAAAGT GCCTCAAGTA TTCCCTAGAT 
ATTGTTAACG GCCTGCTTTT TCTCCACTCA CAAAGCATTT TGCACTTGGA CCTGAAGCCA 
GCGAACATTT TGATCAGTGA GAAGGACGTT TGTAAGATAA GTGACTTCGG CTGCTCCCAG 
AAGCTTCAGG ATCTGCGGTG CCGGCAGGCG TCCCTTCACC ACATCGGGGG CACGTACACG 
CACCAAGCTC CGGAGCTCCT GAAAGGAGAG ATCGCCACGC CCAAAGCCGA CATCTACTCT 
TTTGGCATCA CCCTGTGGCA GATGACCACC AGGGAGGTGC CTTACTCCGG CGAGCCTCAG 
TACGTGCAGT ACGCAGTGGT AGCCTACAAT CTGCGCCCGT CACTGGCAGG GGCGGTGTTC 
ACCGCCTCCC TGACTGGGAA GACGCTGCAG AACATCGTCC AGAGCTGCTG GGAGGCCCGC 
GCCCTGCAGA GGCCGGGTGC AGAACTGCTC CAGAAGGACC TGAAGGCTTT CCGAGGGGCA 
CTGGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mouse Emi2 as a distinctive regulatory hub in second meiotic metaphase.
Development (Cambridge, England)137(19)3281-91(2010 Oct)
Suzuki T,Suzuki E,Yoshida N,Kubo A,Li H,Okuda E,Amanai M,Perry AC

Insufficient amount of Cdc2 and continuous activation of Wee1 B are the cause of meiotic failure in porcine growing oocytes.
The Journal of reproduction and development55(5)553-7(2009 Oct)
Nishimura T,Shimaoka T,Kano K,Naito K

Cytostatic factor proteins are present in male meiotic cells and beta-nerve growth factor increases mos levels in rat late spermatocytes.
PloS one4(10)e7237(2009 Oct)
Perrard MH,Chassaing E,Montillet G,Sabido O,Durand P

Analyses of mitogen-activated protein kinase function in the maturation of porcine oocytes.
Biology of reproduction68(2)604-9(2003 Feb)
Ohashi S,Naito K,Sugiura K,Iwamori N,Goto S,Naruoka H,Tojo H

Successful inactivation of endogenous Oct-3/4 and c-mos genes in mouse preimplantation embryos and oocytes using short interfering RNAs.
Biochemical and biophysical research communications296(5)1372-7(2002 Sep)
Kim MH,Yuan X,Okumura S,Ishikawa F