Dcxr cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Dcxr
Entrez Gene ID	171408
Full Name	dicarbonyl and L-xylulose reductase
Synonyms	glb
General protein information	Preferred Names dicarbonyl and L-xylulose reductase Names L-xylulose reductase XR diacetyl/L-xylulose reductase dicarbonyl L-xylulose reductase
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q32.3
Summary	component of the uronate cycle of glucose metabolism; may be involved in general carbohydrate metabolism [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_134387.1	NP_599214.1	L-xylulose reductase
XM_008768465.2	XP_008766687.1	L-xylulose reductase isoform X1

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008502	XP_316941.3
Caenorhabditis elegans (roundworm)	dhs-21	NP_506182.2
Pan troglodytes (chimpanzee)	DCXR	XP_001167023.2
	DCXR	XP_001112983.1
Canis lupus familiaris (dog)	DCXR	XP_005624203.1
Mus musculus (house mouse)	Dcxr	NP_080704.2
Gallus gallus (chicken)	DCXR	NP_989556.1
Xenopus tropicalis (tropical clawed frog)	dcxr	NP_989100.1
Rattus norvegicus (Norway rat)	Dcxr	NP_599214.1
Homo sapiens (human)	DCXR	NP_057370.1
Bos taurus (cattle)	DCXR	NP_001069359.1
Danio rerio (zebrafish)	dcxr	NP_001017619.1
Drosophila melanogaster (fruit fly)	CG7322	NP_001259693.1

Gene Ontology
Bibliography

Related articles in PubMed

MTR120/KIAA1383, a novel microtubule-associated protein, promotes microtubule stability and ensures cytokinesis.
Fong KW, Leung JW, Li Y, Wang W, Feng L, Ma W, Liu D, Songyang Z, Chen J
Journal of cell science126(Pt 3)825-37(2013 Feb)

Proteomic characterization of the human sperm nucleus.
de Mateo S, Castillo J, Estanyol JM, Ballesc? JL, Oliva R
Proteomics11(13)2714-26(2011 Jul)

Involvement of an aldo-keto reductase (AKR1C3) in redox cycling of 9,10-phenanthrenequinone leading to apoptosis in human endothelial cells.
Matsunaga T, Arakaki M, Kamiya T, Endo S, El-Kabbani O, Hara A
Chemico-biological interactions181(1)52-60(2009 Sep)

Large-scale proteomics and phosphoproteomics of urinary exosomes.
Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)

Identification of amino acid residues involved in substrate recognition of L-xylulose reductase by site-directed mutagenesis.
Ishikura S, Isaji T, Usami N, Nakagawa J, El-Kabbani O, Hara A
Chemico-biological interactions143-144543-50(2003 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Dcxr is highly expressed in kidney and liver (dicarbonyl/L-xylulose reductase)
Title: Molecular characterization of mammalian dicarbonyl/L-xylulose reductase and its localization in kidney.

The following Dcxr gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dcxr cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa44315	XM_008768465.2 Latest version!	Rattus norvegicus dicarbonyl and L-xylulose reductase (Dcxr), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa01271	NM_134387.1 Latest version!	Rattus norvegicus dicarbonyl and L-xylulose reductase (Dcxr), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone	40% OFF
5 or more Clone	50% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Dcxr ( XM_008768465.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008766687.1 Rattus norvegicus dicarbonyl and L-xylulose reductase (Dcxr), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa44315
Clone ID Related Accession (Same CDS sequence)	XM_008768465.2
Accession Version	XM_008768465.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 735bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	L-xylulose reductase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008768465.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACCTGG GTCTTGCAGG TCGGCGGGCG CTGGTCACCG GCGCGGGCAA AGGCATCGGG 
CGCAGCACTG TGCTGGCTTT GCAGGCGGCT GGTGCACAGG TTGTGGCGGT GAGTCGGACG 
CGAGAGGACC TGGACAGCCT GGTCCGGGAG TGTCCTGGTG TGGAGCCTGT GTGTGTGGAC 
CTGGCCGACT GGGAGGCCAC AGAACAGGCC CTAAGCAATG TGGGACCGGT GGACCTTCTG 
GTGAACAATG CTGCTGTGGC TACGTTGCAG CCCTTCCTGG AGGTCACCAA GGAGGCCTGT 
GACACGTCCT TCAACGTGAA TTTTCGGGCT GTCGTCCAGG TGTCGCAGAT TGTGGCCAGG 
GGCATGATAG CTCGGGGAGT TCCAGGGGCC ATTGTGAATG TCTCCAGCCA GGCCTCCCAG 
CGTGCACTGA CCAACCATAC CGTCTACTGT TCCACCAAGG GTGCTTTAGA CATGTTGACC 
AAGGTGATGG CCCTAGAGCT TGGGCCCCAC AAGATCCGTG TGAATGCAGT AAACCCCACA 
GTAGTGATGA CACCCATGGG CCGGGCCAAC TGGAGTGACC CGCACAAAGC TAAGGTCATG 
CTGGATCGTA TCCCACTTGG CAAGTTTGCT GAGGTGGAGA ACGTGGTAGA CACCATCCTC 
TTCCTGCTGA GCAACCGAAG TAGCATGACT ACTGGTTCCG CTTTGCCAGT GGATGGGGGC 
TTCCTGGCTA CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008766687.1
CDS	65..799
Translation	MDLGLAGRRALVTGAGKGIGRSTVLALQAAGAQVVAVSRTREDLDSLVRECPGVEPVCVDLADWEATEQALSNVGPVDLLVNNAAVATLQPFLEVTKEACDTSFNVNFRAVVQVSQIVARGMIARGVPGAIVNVSSQASQRALTNHTVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTPMGRANWSDPHKAKVMLDRIPLGKFAEVENVVDTILFLLSNRSSMTTGSALPVDGGFLAT

Target ORF information:

RefSeq Version	XM_008768465.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dicarbonyl and L-xylulose reductase (Dcxr), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008768465.2

ORF Insert Sequence:

ATGGACCTGG GTCTTGCAGG TCGGCGGGCG CTGGTCACCG GCGCGGGCAA AGGCATCGGG 
CGCAGCACTG TGCTGGCTTT GCAGGCGGCT GGTGCACAGG TTGTGGCGGT GAGTCGGACG 
CGAGAGGACC TGGACAGCCT GGTCCGGGAG TGTCCTGGTG TGGAGCCTGT GTGTGTGGAC 
CTGGCCGACT GGGAGGCCAC AGAACAGGCC CTAAGCAATG TGGGACCGGT GGACCTTCTG 
GTGAACAATG CTGCTGTGGC TACGTTGCAG CCCTTCCTGG AGGTCACCAA GGAGGCCTGT 
GACACGTCCT TCAACGTGAA TTTTCGGGCT GTCGTCCAGG TGTCGCAGAT TGTGGCCAGG 
GGCATGATAG CTCGGGGAGT TCCAGGGGCC ATTGTGAATG TCTCCAGCCA GGCCTCCCAG 
CGTGCACTGA CCAACCATAC CGTCTACTGT TCCACCAAGG GTGCTTTAGA CATGTTGACC 
AAGGTGATGG CCCTAGAGCT TGGGCCCCAC AAGATCCGTG TGAATGCAGT AAACCCCACA 
GTAGTGATGA CACCCATGGG CCGGGCCAAC TGGAGTGACC CGCACAAAGC TAAGGTCATG 
CTGGATCGTA TCCCACTTGG CAAGTTTGCT GAGGTGGAGA ACGTGGTAGA CACCATCCTC 
TTCCTGCTGA GCAACCGAAG TAGCATGACT ACTGGTTCCG CTTTGCCAGT GGATGGGGGC 
TTCCTGGCTA CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dcxr ( NM_134387.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_599214.1 Rattus norvegicus dicarbonyl and L-xylulose reductase (Dcxr), mRNA.

Price & Availability↑

CloneID	ORa01271
Clone ID Related Accession (Same CDS sequence)	NM_134387.1
Accession Version	NM_134387.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 735bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Rattus norvegicus(Norway rat)
Product	L-xylulose reductase
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB061719.1. ##Evidence-Data-START## Transcript exon combination :: AB061719.1, FQ233401.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGACCTGG GGCTTGCAGG TCGGCGGGCG CTGGTCACCG GCGCGGGCAA AGGCATCGGG 
CGCAGCACTG TGCTGGCTTT GCAGGCGGCT GGTGCACAGG TTGTGGCGGT GAGTCGGACG 
CGAGAGGACC TGGACAGCCT GGTCCGGGAG TGTCCTGGTG TGGAGCCTGT GTGTGTGGAC 
CTGGCCGACT GGGAGGCCAC AGAACAGGCC CTAAGCAATG TGGGACCGGT GGACCTTCTG 
GTGAACAATG CTGCTGTGGC TACGTTGCAG CCCTTCCTGG AGGTCACCAA GGAGGCCTGT 
GACACGTCCT TCAACGTGAA TTTTCGGGCT GTCGTCCAGG TGTCGCAGAT TGTGGCNAGG 
GGCATGATAG CTCGGGGAGT TCCAGGGGCC ATTGTGAATG TCTCCAGCCA GGCCTCCCAG 
CGTGCACTGA CCAACCATAC CGTCTACTGT TCCACCAAGG GTGCTTTAGA CATGTTGACC 
AAGGTGATGG CCCTAGAGCT TGGGCCCCAC AAGATCCGTG TGAATGCAGT AAACCCCACA 
GTAGTGATGA CACCCATGGG CCGGGCCAAC TGGAGTGACC CGCACAAAGC TAAGGTCATG 
CTGGATCGTA TCCCACTTGG CAAGTTTGCT GAGGTGGAGA ACGTGGTAGA CACCATCCTC 
TTCCTGCTGA GCAACCGAAG TAGCATGACT ACTGGTTCCG CTTTGCCAGT GGATGGGGGC 
TTCCTGGCTA CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_599214.1
CDS	15..749
Translation	MDLGLAGRRALVTGAGKGIGRSTVLALQAAGAQVVAVSRTREDLDSLVRECPGVEPVCVDLADWEATEQALSNVGPVDLLVNNAAVATLQPFLEVTKEACDTSFNVNFRAVVQVSQIVnullRGMIARGVPGAIVNVSSQASQRALTNHTVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTPMGRANWSDPHKAKVMLDRIPLGKFAEVENVVDTILFLLSNRSSMTTGSALPVDGGFLAT

Target ORF information:

RefSeq Version	NM_134387.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dicarbonyl and L-xylulose reductase (Dcxr), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_134387.1

ORF Insert Sequence:

ATGGACCTGG GGCTTGCAGG TCGGCGGGCG CTGGTCACCG GCGCGGGCAA AGGCATCGGG 
CGCAGCACTG TGCTGGCTTT GCAGGCGGCT GGTGCACAGG TTGTGGCGGT GAGTCGGACG 
CGAGAGGACC TGGACAGCCT GGTCCGGGAG TGTCCTGGTG TGGAGCCTGT GTGTGTGGAC 
CTGGCCGACT GGGAGGCCAC AGAACAGGCC CTAAGCAATG TGGGACCGGT GGACCTTCTG 
GTGAACAATG CTGCTGTGGC TACGTTGCAG CCCTTCCTGG AGGTCACCAA GGAGGCCTGT 
GACACGTCCT TCAACGTGAA TTTTCGGGCT GTCGTCCAGG TGTCGCAGAT TGTGGCNAGG 
GGCATGATAG CTCGGGGAGT TCCAGGGGCC ATTGTGAATG TCTCCAGCCA GGCCTCCCAG 
CGTGCACTGA CCAACCATAC CGTCTACTGT TCCACCAAGG GTGCTTTAGA CATGTTGACC 
AAGGTGATGG CCCTAGAGCT TGGGCCCCAC AAGATCCGTG TGAATGCAGT AAACCCCACA 
GTAGTGATGA CACCCATGGG CCGGGCCAAC TGGAGTGACC CGCACAAAGC TAAGGTCATG 
CTGGATCGTA TCCCACTTGG CAAGTTTGCT GAGGTGGAGA ACGTGGTAGA CACCATCCTC 
TTCCTGCTGA GCAACCGAAG TAGCATGACT ACTGGTTCCG CTTTGCCAGT GGATGGGGGC 
TTCCTGGCTA CCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

MTR120/KIAA1383, a novel microtubule-associated protein, promotes microtubule stability and ensures cytokinesis.
Journal of cell science126(Pt 3)825-37(2013 Feb)
Fong KW,Leung JW,Li Y,Wang W,Feng L,Ma W,Liu D,Songyang Z,Chen J

Proteomic characterization of the human sperm nucleus.
Proteomics11(13)2714-26(2011 Jul)
de Mateo S,Castillo J,Estanyol JM,Ballesc? JL,Oliva R

Involvement of an aldo-keto reductase (AKR1C3) in redox cycling of 9,10-phenanthrenequinone leading to apoptosis in human endothelial cells.
Chemico-biological interactions181(1)52-60(2009 Sep)
Matsunaga T,Arakaki M,Kamiya T,Endo S,El-Kabbani O,Hara A

Large-scale proteomics and phosphoproteomics of urinary exosomes.
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)
Gonzales PA,Pisitkun T,Hoffert JD,Tchapyjnikov D,Star RA,Kleta R,Wang NS,Knepper MA

Identification of amino acid residues involved in substrate recognition of L-xylulose reductase by site-directed mutagenesis.
Chemico-biological interactions143-144543-50(2003 Feb)
Ishikura S,Isaji T,Usami N,Nakagawa J,El-Kabbani O,Hara A