Foxd1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Foxd1
Entrez Gene ID	171299
Full Name	forkhead box D1
Synonyms	BF-2,Hfhbf2
General protein information	Preferred Names forkhead box D1 Names forkhead box protein D1 brain factor 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q12
Summary	mediates the coordinated expression of hepatocyte-specific genes [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_134337.1	NP_599164.1	forkhead box protein D1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Foxd1	NP_032268.2
Homo sapiens (human)	FOXD1	NP_004463.1
Pan troglodytes (chimpanzee)	FOXD1	XP_001141603.2
Rattus norvegicus (Norway rat)	Foxd1	NP_599164.1

Gene Ontology
Bibliography

Related articles in PubMed

The forkhead transcription factor, Foxd1, is necessary for pituitary luteinizing hormone expression in mice.
Gumbel JH, Patterson EM, Owusu SA, Kabat BE, Jung DO, Simmons J, Hopkins T, Ellsworth BS
PloS one7(12)e52156(2012)

Foxd1-dependent signals control cellularity in the renal capsule, a structure required for normal renal development.
Levinson RS, Batourina E, Choi C, Vorontchikhina M, Kitajewski J, Mendelsohn CL
Development (Cambridge, England)132(3)529-39(2005 Feb)

Foxd1 is required for proper formation of the optic chiasm.
Herrera E, Marcus R, Li S, Williams SE, Erskine L, Lai E, Mason C
Development (Cambridge, England)131(22)5727-39(2004 Nov)

Transcriptional activation of placental growth factor by the forkhead/winged helix transcription factor FoxD1.
Zhang H, Palmer R, Gao X, Kreidberg J, Gerald W, Hsiao L, Jensen RV, Gullans SR, Haber DA
Current biology : CB13(18)1625-9(2003 Sep)

Mechanisms of FOXC2- and FOXD1-mediated regulation of the RI alpha subunit of cAMP-dependent protein kinase include release of transcriptional repression and activation by protein kinase B alpha and cAMP.
Dahle MK, Gr?nning LM, Cederberg A, Blomhoff HK, Miura N, Enerb?ck S, Task?n KA, Task?n K
The Journal of biological chemistry277(25)22902-8(2002 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Mechanisms of FOXC2- and FOXD1-mediated regulation of the RI alpha subunit of cAMP-dependent protein kinase include release of transcriptional repression and activation by protein kinase B alpha and cAMP.
Title: Mechanisms of FOXC2- and FOXD1-mediated regulation of the RI alpha subunit of cAMP-dependent protein kinase include release of transcriptional repression and activation by protein kinase B alpha and cAMP.

The following Foxd1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Foxd1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa00016	NM_134337.1 Latest version!	Rattus norvegicus forkhead box D1 (Foxd1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Foxd1 ( NM_134337.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_599164.1 Rattus norvegicus forkhead box D1 (Foxd1), mRNA.

Price & Availability↑

CloneID	ORa00016
Clone ID Related Accession (Same CDS sequence)	NM_134337.1
Accession Version	NM_134337.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1368bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-19
Organism	Rattus norvegicus(Norway rat)
Product	forkhead box protein D1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC119356.6 and AABR07072696.1. On Apr 6, 2013 this sequence version replaced XM_001057782.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments and orthologous data. ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END##

ATGACCCTGA GCACAGAGAT GTCCGATGCC TCCGGCCTCG CCGAGGAGAC AGACATCGAC 
GTGGTGGGGG AGGGAGAGGA CGAAGAGGAG GAAGAGGACG ATGACGACGA GGGCGGCGGC 
GGGTCCCAGT TGCCCAGCTC GGCCCAGCGG CGGCGGCGCT CCTACGCCGG GGAGGACGAG 
CTCGAGGACC TGGAGGAAGA GGACGACGAC GAAGACCTGC TGCTGGCCTC GCGGCCTGCC 
GCGTCCCCCG CGCCTCCGGG TCCTGCGCCC GCCCCAGGGG CCGGATCGGG CGGCTGCAGC 
GGCGCGGGAG CGGGAGGCGG CGCGGGAGGT GGCGTGGGCG CGGGCGCGGG CACGGGTGGG 
GGCGGGAGCT CCAAGAACCC GCTGGTGAAG CCTCCCTACT CGTACATCGC GCTCATCACC 
ATGGCCATCC TGCAGAGCCC CAAGAAGCGC CTGACGCTCA GCGAGATCTG CGAGTTCATC 
AGCGGTCGCT TCCCTTACTA CCGGGAGAAG TTCCCCGCCT GGCAGAACAG CATCCGTCAC 
AACCTGTCGC TCAACGACTG CTTCGTCAAG ATCCCGCGCG AGCCCGGCAA CCCGGGCAAG 
GGCAACTACT GGACGCTCGA CCCGGAGTCC GCAGACATGT TCGACAACGG CAGCTTCCTG 
CGGCGCCGCA AGCGCTTCAA GCGCCAGCCG TTGCTCGCCC CCCACGCGGC GGCCGAGGCG 
CTGCTGCTGC GCGGTGCGGG GCCCGCGGCG AGCGCAGGGG ACCCGGGCGC CGCGCTCTTC 
CCGCCGCCGC CCCCGCCGAC CGCCTGCGGC TATGGAGCCT ACGGCTGCGC CTACGGCCTG 
CAGCTGCCGC CCTGCGCGCC GCCCTCCGCG CTCTTCGCTG CCGCCGCCGC CGCAGCCGCT 
GCCGCCTTCC ACCCGCACTC ACCCCCGCCA CCGCCGCCGC CGCCGCCTCC TCCCGGCGCG 
GCCGCCGAGC TGGCGCGGAC CGCCTTCGGC TACCGGCCGC ATGCGCTGGC CGCCGCCCTG 
CCCGGCCCGT TGCAGGCGGC CGCAGTCAAG GCGGGAGGCC CGGGCACCGC AGCGCTCGCA 
CGCTCGCCCT TCTCCATTGA GAGCCTCATC GGGCGCACTC GGGGTCCCGC GACCGCCGGT 
GCACACGCCT CGCCTGGGGC CACCAGCGGG ACCGCACCGG GCCCCGGGGG CGGAGGCTGC 
GCCGTGCAAG CGGCTGCGGG TCCCGCCGTC GCGCTCACCC GCTCGCTGGT GGTCGCCGCC 
GCGGCTGCTG CCTCCTCCGT GTCGTCGTCC GCCGCGCTGG GTACTCTGCA CCAAGGGACT 
GCGCTGTCCA GTGTGGAGAA CTTTACTGCT AGGATTTCCA ATTGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_599164.1
CDS	363..1730
Translation	MTLSTEMSDASGLAEETDIDVVGEGEDEEEEEDDDDEGGGGSQLPSSAQRRRRSYAGEDELEDLEEEDDDEDLLLASRPAASPAPPGPAPAPGAGSGGCSGAGAGGGAGGGVGAGAGTGGGGSSKNPLVKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKRQPLLAPHAAAEALLLRGAGPAASAGDPGAALFPPPPPPTACGYGAYGCAYGLQLPPCAPPSALFAAAAAAAAAAFHPHSPPPPPPPPPPPGAAAELARTAFGYRPHALAAALPGPLQAAAVKAGGPGTAALARSPFSIESLIGRTRGPATAGAHASPGATSGTAPGPGGGGCAVQAAAGPAVALTRSLVVAAAAAASSVSSSAALGTLHQGTALSSVENFTARISNC

Target ORF information:

RefSeq Version	NM_134337.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus forkhead box D1 (Foxd1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_134337.1

ORF Insert Sequence:

ATGACCCTGA GCACAGAGAT GTCCGATGCC TCCGGCCTCG CCGAGGAGAC AGACATCGAC 
GTGGTGGGGG AGGGAGAGGA CGAAGAGGAG GAAGAGGACG ATGACGACGA GGGCGGCGGC 
GGGTCCCAGT TGCCCAGCTC GGCCCAGCGG CGGCGGCGCT CCTACGCCGG GGAGGACGAG 
CTCGAGGACC TGGAGGAAGA GGACGACGAC GAAGACCTGC TGCTGGCCTC GCGGCCTGCC 
GCGTCCCCCG CGCCTCCGGG TCCTGCGCCC GCCCCAGGGG CCGGATCGGG CGGCTGCAGC 
GGCGCGGGAG CGGGAGGCGG CGCGGGAGGT GGCGTGGGCG CGGGCGCGGG CACGGGTGGG 
GGCGGGAGCT CCAAGAACCC GCTGGTGAAG CCTCCCTACT CGTACATCGC GCTCATCACC 
ATGGCCATCC TGCAGAGCCC CAAGAAGCGC CTGACGCTCA GCGAGATCTG CGAGTTCATC 
AGCGGTCGCT TCCCTTACTA CCGGGAGAAG TTCCCCGCCT GGCAGAACAG CATCCGTCAC 
AACCTGTCGC TCAACGACTG CTTCGTCAAG ATCCCGCGCG AGCCCGGCAA CCCGGGCAAG 
GGCAACTACT GGACGCTCGA CCCGGAGTCC GCAGACATGT TCGACAACGG CAGCTTCCTG 
CGGCGCCGCA AGCGCTTCAA GCGCCAGCCG TTGCTCGCCC CCCACGCGGC GGCCGAGGCG 
CTGCTGCTGC GCGGTGCGGG GCCCGCGGCG AGCGCAGGGG ACCCGGGCGC CGCGCTCTTC 
CCGCCGCCGC CCCCGCCGAC CGCCTGCGGC TATGGAGCCT ACGGCTGCGC CTACGGCCTG 
CAGCTGCCGC CCTGCGCGCC GCCCTCCGCG CTCTTCGCTG CCGCCGCCGC CGCAGCCGCT 
GCCGCCTTCC ACCCGCACTC ACCCCCGCCA CCGCCGCCGC CGCCGCCTCC TCCCGGCGCG 
GCCGCCGAGC TGGCGCGGAC CGCCTTCGGC TACCGGCCGC ATGCGCTGGC CGCCGCCCTG 
CCCGGCCCGT TGCAGGCGGC CGCAGTCAAG GCGGGAGGCC CGGGCACCGC AGCGCTCGCA 
CGCTCGCCCT TCTCCATTGA GAGCCTCATC GGGCGCACTC GGGGTCCCGC GACCGCCGGT 
GCACACGCCT CGCCTGGGGC CACCAGCGGG ACCGCACCGG GCCCCGGGGG CGGAGGCTGC 
GCCGTGCAAG CGGCTGCGGG TCCCGCCGTC GCGCTCACCC GCTCGCTGGT GGTCGCCGCC 
GCGGCTGCTG CCTCCTCCGT GTCGTCGTCC GCCGCGCTGG GTACTCTGCA CCAAGGGACT 
GCGCTGTCCA GTGTGGAGAA CTTTACTGCT AGGATTTCCA ATTGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The forkhead transcription factor, Foxd1, is necessary for pituitary luteinizing hormone expression in mice.
PloS one7(12)e52156(2012)
Gumbel JH,Patterson EM,Owusu SA,Kabat BE,Jung DO,Simmons J,Hopkins T,Ellsworth BS

Foxd1-dependent signals control cellularity in the renal capsule, a structure required for normal renal development.
Development (Cambridge, England)132(3)529-39(2005 Feb)
Levinson RS,Batourina E,Choi C,Vorontchikhina M,Kitajewski J,Mendelsohn CL

Foxd1 is required for proper formation of the optic chiasm.
Development (Cambridge, England)131(22)5727-39(2004 Nov)
Herrera E,Marcus R,Li S,Williams SE,Erskine L,Lai E,Mason C

Transcriptional activation of placental growth factor by the forkhead/winged helix transcription factor FoxD1.
Current biology : CB13(18)1625-9(2003 Sep)
Zhang H,Palmer R,Gao X,Kreidberg J,Gerald W,Hsiao L,Jensen RV,Gullans SR,Haber DA

Mechanisms of FOXC2- and FOXD1-mediated regulation of the RI alpha subunit of cAMP-dependent protein kinase include release of transcriptional repression and activation by protein kinase B alpha and cAMP.
The Journal of biological chemistry277(25)22902-8(2002 Jun)
Dahle MK,Gr?nning LM,Cederberg A,Blomhoff HK,Miura N,Enerb?ck S,Task?n KA,Task?n K