Cetn3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cetn3
Entrez Gene ID	170895
Full Name	centrin 3
General protein information	Preferred Names centrin 3 Names centrin-3 centrin, EF-hand protein, 3 (CDC31 homolog, yeast)
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q11
Summary	human homolog may be involved in regulation of role in spindle pole body duplication during the cell cycle [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001191842.1	NP_001178771.1	centrin-3

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Cetn3	NP_001178771.1
Rattus norvegicus (Norway rat)	LOC100912538	XP_003749211.1

Gene Ontology
Bibliography

Related articles in PubMed

MDM1 is a microtubule-binding protein that negatively regulates centriole duplication.
Van de Mark D, Kong D, Loncarek J, Stearns T
Molecular biology of the cell26(21)3788-802(2015 Nov)

Disruption of the retinitis pigmentosa 28 gene Fam161a in mice affects photoreceptor ciliary structure and leads to progressive retinal degeneration.
Karlstetter M, Sorusch N, Caramoy A, Dannhausen K, Aslanidis A, Fauser S, Boesl MR, Nagel-Wolfrum K, Tamm ER, J?gle H, Stoehr H, Wolfrum U, Langmann T
Human molecular genetics23(19)5197-210(2014 Oct)

The human TREX-2 complex is stably associated with the nuclear pore basket.
Umlauf D, Bonnet J, Waharte F, Fournier M, Stierle M, Fischer B, Brino L, Devys D, Tora L
Journal of cell science126(Pt 12)2656-67(2013 Jun)

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.
Jakobsen L, Vanselow K, Skogs M, Toyoda Y, Lundberg E, Poser I, Falkenby LG, Bennetzen M, Westendorf J, Nigg EA, Uhlen M, Hyman AA, Andersen JS
The EMBO journal30(8)1520-35(2011 Apr)

The centrosomal protein pericentrin identified at the basal body complex of the connecting cilium in mouse photoreceptors.
M?hlhans J, Brandst?tter JH, Giessl A
PloS one6(10)e26496(2011)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cetn3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cetn3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa07804	NM_001191842.1 Latest version!	Rattus norvegicus centrin 3 (Cetn3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cetn3 ( NM_001191842.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001178771.1 Rattus norvegicus centrin 3 (Cetn3), mRNA.

Price & Availability↑

CloneID	ORa07804
Clone ID Related Accession (Same CDS sequence)	NM_001191842.1
Accession Version	NM_001191842.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 504bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	centrin-3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AABR07007389.1. On Jul 17, 2010 this sequence version replaced XM_342168.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: FM090102.1, BG666074.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGAGTTTAG CTCTGAGAGG TGAGCTTGTA GTAGACAAAA CAAAAAGGAA AAAACGAAGA 
GAACTCTCTG AAGAACAGAA GCAAGAAATT AAAGATGCTT TTGAACTGTT TGATACCGAC 
AAAGACCAAG CCATAGATTA TCATGAATTA AAGGTGGCAA TGAGAGCCTT GGGTTTTGAT 
GTGAAAAAGG CGGATGTATT GAAGATTCTT AAAGATTATG ACAGAGAAGC CACAGGCAAG 
ATCACATTTG AAGATTTTAA TGAAGTTGTG ACAGACTGGA TACTAGAAAG AGATCCACAC 
GAGGAGATCC TGAAAGCATT TAAACTATTT GATGATGATG ATTCAGGAAA GATAAGCTTG 
AGGAACTTGC GCCGTGTTGC CCGAGAGCTG GGTGAGAATA TGAGCGATGA GGAGCTCCGG 
GCCATGATCG AGGAGTTTGA TAAGGACGGC GATGGGGAGA TAAATCAAGA GGAATTCATT 
GCTATTATGA CTGGTGACAT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001178771.1
CDS	89..592
Translation	MSLALRGELVVDKTKRKKRRELSEEQKQEIKDAFELFDTDKDQAIDYHELKVAMRALGFDVKKADVLKILKDYDREATGKITFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINQEEFIAIMTGDI

Target ORF information:

RefSeq Version	NM_001191842.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus centrin 3 (Cetn3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001191842.1

ORF Insert Sequence:

ATGAGTTTAG CTCTGAGAGG TGAGCTTGTA GTAGACAAAA CAAAAAGGAA AAAACGAAGA 
GAACTCTCTG AAGAACAGAA GCAAGAAATT AAAGATGCTT TTGAACTGTT TGATACCGAC 
AAAGACCAAG CCATAGATTA TCATGAATTA AAGGTGGCAA TGAGAGCCTT GGGTTTTGAT 
GTGAAAAAGG CGGATGTATT GAAGATTCTT AAAGATTATG ACAGAGAAGC CACAGGCAAG 
ATCACATTTG AAGATTTTAA TGAAGTTGTG ACAGACTGGA TACTAGAAAG AGATCCACAC 
GAGGAGATCC TGAAAGCATT TAAACTATTT GATGATGATG ATTCAGGAAA GATAAGCTTG 
AGGAACTTGC GCCGTGTTGC CCGAGAGCTG GGTGAGAATA TGAGCGATGA GGAGCTCCGG 
GCCATGATCG AGGAGTTTGA TAAGGACGGC GATGGGGAGA TAAATCAAGA GGAATTCATT 
GCTATTATGA CTGGTGACAT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

MDM1 is a microtubule-binding protein that negatively regulates centriole duplication.
Molecular biology of the cell26(21)3788-802(2015 Nov)
Van de Mark D,Kong D,Loncarek J,Stearns T

Disruption of the retinitis pigmentosa 28 gene Fam161a in mice affects photoreceptor ciliary structure and leads to progressive retinal degeneration.
Human molecular genetics23(19)5197-210(2014 Oct)
Karlstetter M,Sorusch N,Caramoy A,Dannhausen K,Aslanidis A,Fauser S,Boesl MR,Nagel-Wolfrum K,Tamm ER,J?gle H,Stoehr H,Wolfrum U,Langmann T

The human TREX-2 complex is stably associated with the nuclear pore basket.
Journal of cell science126(Pt 12)2656-67(2013 Jun)
Umlauf D,Bonnet J,Waharte F,Fournier M,Stierle M,Fischer B,Brino L,Devys D,Tora L

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.
The EMBO journal30(8)1520-35(2011 Apr)
Jakobsen L,Vanselow K,Skogs M,Toyoda Y,Lundberg E,Poser I,Falkenby LG,Bennetzen M,Westendorf J,Nigg EA,Uhlen M,Hyman AA,Andersen JS

The centrosomal protein pericentrin identified at the basal body complex of the connecting cilium in mouse photoreceptors.
PloS one6(10)e26496(2011)
M?hlhans J,Brandst?tter JH,Giessl A