Faf1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Faf1
Entrez Gene ID	140657
Full Name	Fas associated factor 1
General protein information	Preferred Names Fas associated factor 1 Names FAS-associated factor 1 Fas (TNFRSF6) associated factor 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q35
Summary	human homolog is a member of a protein complex involved in Fas-mediated apoptosis; plays a role in negative regulation of NF-kappaB activation [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_130406.1	NP_569090.1	FAS-associated factor 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	FAF1	XP_001137725.1
Gallus gallus (chicken)	FAF1	XP_422464.4
Drosophila melanogaster (fruit fly)	casp	NP_611080.1
Homo sapiens (human)	FAF1	NP_008982.1
Danio rerio (zebrafish)	faf1	NP_998138.1
Canis lupus familiaris (dog)	FAF1	XP_849822.1
Bos taurus (cattle)	FAF1	NP_001039783.1
	FAF1	XP_001104146.2
Rattus norvegicus (Norway rat)	Faf1	NP_569090.1
Mus musculus (house mouse)	Faf1	NP_032009.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006473	XP_316513.4
Xenopus tropicalis (tropical clawed frog)	faf1	XP_002931465.1

Gene Ontology
Bibliography

Related articles in PubMed

Chromatin-associated degradation is defined by UBXN-3/FAF1 to safeguard DNA replication fork progression.
Franz A, Pirson PA, Pilger D, Halder S, Achuthankutty D, Kashkar H, Ramadan K, Hoppe T
Nature communications710612(2016 Feb)

Interactions of the mineralocorticoid receptor--within and without.
Yang J, Fuller PJ
Molecular and cellular endocrinology350(2)196-205(2012 Mar)

UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover.
Alexandru G, Graumann J, Smith GT, Kolawa NJ, Fang R, Deshaies RJ
Cell134(5)804-16(2008 Sep)

Fas-associated factor-1 mediates chemotherapeutic-induced apoptosis via death effector filament formation.
Park MY, Ryu SW, Kim KD, Lim JS, Lee ZW, Kim E
International journal of cancer115(3)412-8(2005 Jun)

Human Fas-associated factor 1, interacting with ubiquitinated proteins and valosin-containing protein, is involved in the ubiquitin-proteasome pathway.
Song EJ, Yim SH, Kim E, Kim NS, Lee KJ
Molecular and cellular biology25(6)2511-24(2005 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Faf1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Faf1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa00356	NM_130406.1 Latest version!	Rattus norvegicus Fas associated factor 1 (Faf1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Faf1 ( NM_130406.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_569090.1 Rattus norvegicus Fas associated factor 1 (Faf1), mRNA.

Price & Availability↑

CloneID	ORa00356
Clone ID Related Accession (Same CDS sequence)	NM_130406.1
Accession Version	NM_130406.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1950bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Rattus norvegicus(Norway rat)
Product	FAS-associated factor 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF293459.1. ##Evidence-Data-START## Transcript exon combination :: AF293459.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCGTCCA ACATGGACCG GGAGATGATC CTTGCGGATT TTCAGGCATG TACTGGTATT 
GAAAACATTG ATGAAGCTAT TACACTGCTT GAGCAAAATA ACTGGGACTT GGTGGCAGCT 
ATCAATGGTG TAATACCCCA GGAAAATGGC ATTCTACAAA GTGACTTTGG AGGTGAGACC 
ATGCCAGGAC CCACATTTGA CCCAGCAAGT CCACCTGCTC CAGCTCCAGC TCCCTCTTCT 
TCCGCGTTCC GACCTGTAAT GCCATCCAGG CAGATCGTAG AAAGGCAGCC GCGCATGCTC 
GACTTCAGAG TTGAATACAG GGACAGGAAT GTTGATGTGG TACTTGAAGA CAGCTGTACT 
GTTGGAGAGA TTAAACAGAT TCTAGAAAAT GAACTTCAGA TACCTGTGCC TAAAATGCTG 
TTGAAAGGCT GGAAGACTGG AGATGTGGAA GACAGTACGG TCTTAAAATC ACTACACTTG 
CCAAAAAACA ACAGTCTTTA TGTCCTTACA CCAGACTTAC CACCACCTTC ATCATCCAGT 
CATGCTGGTG CCCTGCAGGA ATCATTAAAT CAAAACTTCA TGCTGATCAT CACCCACCGA 
GAGGTCCAGC GGGAGTACAA CCTGAACTTC TCAGGAAGCA GTACCGTTCA AGAGGTAAAG 
AGAAATGTGT ATGATCTGAC AAGCATACCT GTTCGACATC AGTTATGGGA AGGCTGGCCA 
GCTTCTGCCA CTGATGATTC AATGTGTCTT GCTGAATCAG GGCTCTCTTA TCCCTGCCAT 
CGACTCACTG TGGGACGAAG AACTTCACCT GTACAGACCC GTGAGCAATC AGAAGAGCAA 
AGCACGGTAG TTCATATGGT TAGTGATAGT GATGGAGATG ACTTTGAAGA TGCTTCAGAA 
TTTGGAGTGG TAGACGGAGA AGTATTTGGC ATGGCATCAT CTACCATGAG AAAATCTCCA 
ATGATGCCAG AAAACGCAGA AAATGAAGGA GATGCCTTAT TACAATTTAC AGCAGAGTTT 
TCTTCAAGAT ATGGTGACTG CCATCCTGTA TTTTTTATTG GCTCATTAGA AGCTGCTTTC 
CAAGAGGCCT TCTATGTGAA AGCCAGAGAC AGAAAGCTTC TTGCTATCTA CCTCCACCAT 
GATGAAAGTG TACTAACCAA CGTGTTCTGC TCACAAATGC TTTGTGCTGA ATCCATTGTT 
TCTTATCTGA GTCAAAATTT TATAACCTGG GCTTGGGATC TGACAAAGGA CGCCAACAGA 
GCAAGATTTC TGACAATGTG CAATAGACAC TTTGGCAGCG TTATTGCACA AACCATTCGG 
ACTCAAAAGA CAGATCAGTT TCCACTTTTC CTGATTATCA TGGGAAAGCG ATCATCTAAT 
GAAGTGCTAA ATGTGATACA AGGTAATACA ACAGTGGATG AGTTAATGAT GAGACTCATG 
GCTGCCATGG AGATTTTCTC AGCTCAACAA CAGGAAGACA TAAAGGATGA GGATGAACGT 
GAAGCCAGAG AAAATGTGAA GAGAGAGCAA GATGAGGCTT ATCGCCTTTC CCTTGAAGCC 
GACAGGGCAA AGAGAGAAGC TCATGAGAGA GAGATGGCAG AACAGTTTCG TTTGGAGCAG 
ATTCGCAAAG AGCAAGAAGA GGAACGCGAG GCCATCAGAC TCTCCTTAGA ACAAGCCCTG 
CCTCCAGAGC CAGAGGAGGA AAATGCGGAG CCTGTTAGCA AGCTTCGGAT TCGAACCCCC 
AGTGGCGAGT TCCTGGAACG CCGTTTCCTG GCCAGCAATA AGCTCCAGAT TGTCTTTGAT 
TTTGTGGCTT CCAAGGGATT TCCTTGGGAT GAGTTCAAGT TACTGAGCAC CTTTCCTAGG 
AGAGACGTAA CTCAGCTAGA CCCCAATAAG TCATTATTGG AGGTAAACTT GTTCCCTCAA 
GAAACCCTTT TCCTTCTAGC AAAAGAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_569090.1
CDS	250..2199
Translation	MASNMDREMILADFQACTGIENIDEAITLLEQNNWDLVAAINGVIPQENGILQSDFGGETMPGPTFDPASPPAPAPAPSSSAFRPVMPSRQIVERQPRMLDFRVEYRDRNVDVVLEDSCTVGEIKQILENELQIPVPKMLLKGWKTGDVEDSTVLKSLHLPKNNSLYVLTPDLPPPSSSSHAGALQESLNQNFMLIITHREVQREYNLNFSGSSTVQEVKRNVYDLTSIPVRHQLWEGWPASATDDSMCLAESGLSYPCHRLTVGRRTSPVQTREQSEEQSTVVHMVSDSDGDDFEDASEFGVVDGEVFGMASSTMRKSPMMPENAENEGDALLQFTAEFSSRYGDCHPVFFIGSLEAAFQEAFYVKARDRKLLAIYLHHDESVLTNVFCSQMLCAESIVSYLSQNFITWAWDLTKDANRARFLTMCNRHFGSVIAQTIRTQKTDQFPLFLIIMGKRSSNEVLNVIQGNTTVDELMMRLMAAMEIFSAQQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRKEQEEEREAIRLSLEQALPPEPEEENAEPVSKLRIRTPSGEFLERRFLASNKLQIVFDFVASKGFPWDEFKLLSTFPRRDVTQLDPNKSLLEVNLFPQETLFLLAKE

Target ORF information:

RefSeq Version	NM_130406.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Fas associated factor 1 (Faf1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_130406.1

ORF Insert Sequence:

ATGGCGTCCA ACATGGACCG GGAGATGATC CTTGCGGATT TTCAGGCATG TACTGGTATT 
GAAAACATTG ATGAAGCTAT TACACTGCTT GAGCAAAATA ACTGGGACTT GGTGGCAGCT 
ATCAATGGTG TAATACCCCA GGAAAATGGC ATTCTACAAA GTGACTTTGG AGGTGAGACC 
ATGCCAGGAC CCACATTTGA CCCAGCAAGT CCACCTGCTC CAGCTCCAGC TCCCTCTTCT 
TCCGCGTTCC GACCTGTAAT GCCATCCAGG CAGATCGTAG AAAGGCAGCC GCGCATGCTC 
GACTTCAGAG TTGAATACAG GGACAGGAAT GTTGATGTGG TACTTGAAGA CAGCTGTACT 
GTTGGAGAGA TTAAACAGAT TCTAGAAAAT GAACTTCAGA TACCTGTGCC TAAAATGCTG 
TTGAAAGGCT GGAAGACTGG AGATGTGGAA GACAGTACGG TCTTAAAATC ACTACACTTG 
CCAAAAAACA ACAGTCTTTA TGTCCTTACA CCAGACTTAC CACCACCTTC ATCATCCAGT 
CATGCTGGTG CCCTGCAGGA ATCATTAAAT CAAAACTTCA TGCTGATCAT CACCCACCGA 
GAGGTCCAGC GGGAGTACAA CCTGAACTTC TCAGGAAGCA GTACCGTTCA AGAGGTAAAG 
AGAAATGTGT ATGATCTGAC AAGCATACCT GTTCGACATC AGTTATGGGA AGGCTGGCCA 
GCTTCTGCCA CTGATGATTC AATGTGTCTT GCTGAATCAG GGCTCTCTTA TCCCTGCCAT 
CGACTCACTG TGGGACGAAG AACTTCACCT GTACAGACCC GTGAGCAATC AGAAGAGCAA 
AGCACGGTAG TTCATATGGT TAGTGATAGT GATGGAGATG ACTTTGAAGA TGCTTCAGAA 
TTTGGAGTGG TAGACGGAGA AGTATTTGGC ATGGCATCAT CTACCATGAG AAAATCTCCA 
ATGATGCCAG AAAACGCAGA AAATGAAGGA GATGCCTTAT TACAATTTAC AGCAGAGTTT 
TCTTCAAGAT ATGGTGACTG CCATCCTGTA TTTTTTATTG GCTCATTAGA AGCTGCTTTC 
CAAGAGGCCT TCTATGTGAA AGCCAGAGAC AGAAAGCTTC TTGCTATCTA CCTCCACCAT 
GATGAAAGTG TACTAACCAA CGTGTTCTGC TCACAAATGC TTTGTGCTGA ATCCATTGTT 
TCTTATCTGA GTCAAAATTT TATAACCTGG GCTTGGGATC TGACAAAGGA CGCCAACAGA 
GCAAGATTTC TGACAATGTG CAATAGACAC TTTGGCAGCG TTATTGCACA AACCATTCGG 
ACTCAAAAGA CAGATCAGTT TCCACTTTTC CTGATTATCA TGGGAAAGCG ATCATCTAAT 
GAAGTGCTAA ATGTGATACA AGGTAATACA ACAGTGGATG AGTTAATGAT GAGACTCATG 
GCTGCCATGG AGATTTTCTC AGCTCAACAA CAGGAAGACA TAAAGGATGA GGATGAACGT 
GAAGCCAGAG AAAATGTGAA GAGAGAGCAA GATGAGGCTT ATCGCCTTTC CCTTGAAGCC 
GACAGGGCAA AGAGAGAAGC TCATGAGAGA GAGATGGCAG AACAGTTTCG TTTGGAGCAG 
ATTCGCAAAG AGCAAGAAGA GGAACGCGAG GCCATCAGAC TCTCCTTAGA ACAAGCCCTG 
CCTCCAGAGC CAGAGGAGGA AAATGCGGAG CCTGTTAGCA AGCTTCGGAT TCGAACCCCC 
AGTGGCGAGT TCCTGGAACG CCGTTTCCTG GCCAGCAATA AGCTCCAGAT TGTCTTTGAT 
TTTGTGGCTT CCAAGGGATT TCCTTGGGAT GAGTTCAAGT TACTGAGCAC CTTTCCTAGG 
AGAGACGTAA CTCAGCTAGA CCCCAATAAG TCATTATTGG AGGTAAACTT GTTCCCTCAA 
GAAACCCTTT TCCTTCTAGC AAAAGAGTAA