Hmgn2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Hmgn2
Entrez Gene ID	114637
Full Name	high mobility group nucleosomal binding domain 2
Synonyms	Hmg17
General protein information	Preferred Names high mobility group nucleosomal binding domain 2 Names non-histone chromosomal protein HMG-17 high mobility group nucleosome binding domain 2 high mobility group nucleosome-binding domain-containing protein 2 high mobility group protein 17
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q36
Summary	member of a family of non-histone chromosomal proteins [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001025624.2	NP_001020795.1	non-histone chromosomal protein HMG-17

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Hmgn2	NP_058653.1
Rattus norvegicus (Norway rat)	LOC100360316	XP_003751635.1
	LOC702326	XP_001090611.1
Pan troglodytes (chimpanzee)	LOC749317	XP_001167647.1
Gallus gallus (chicken)	HMGN2	NP_001072953.1
Mus musculus (house mouse)	Gm6750	XP_001478610.1
Rattus norvegicus (Norway rat)	Hmgn2	NP_001020795.1
Mus musculus (house mouse)	Gm7931	XP_006504302.1

Gene Ontology
Bibliography

Related articles in PubMed

A model for the molecular underpinnings of tooth defects in Axenfeld-Rieger syndrome.
Li X, Venugopalan SR, Cao H, Pinho FO, Paine ML, Snead ML, Semina EV, Amendt BA
Human molecular genetics23(1)194-208(2014 Jan)

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz AG, Munschauer M, Schwanh?usser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C, Landthaler M
Molecular cell46(5)674-90(2012 Jun)

Effects of HMGN variants on the cellular transcription profile.
Rochman M, Taher L, Kurahashi T, Cherukuri S, Uversky VN, Landsman D, Ovcharenko I, Bustin M
Nucleic acids research39(10)4076-87(2011 May)

HMGN2: a novel antimicrobial effector molecule of human mononuclear leukocytes?
Feng Y, Huang N, Wu Q, Wang B
Journal of leukocyte biology78(5)1136-41(2005 Nov)

Cytokine-induced down-regulation of zfm1/splicing factor-1 promotes smooth muscle cell proliferation.
Cattaruzza M, Sch?fer K, Hecker M
The Journal of biological chemistry277(8)6582-9(2002 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Hmgn2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hmgn2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa07672	NM_001025624.2 Latest version!	Rattus norvegicus high mobility group nucleosomal binding domain 2 (Hmgn2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Hmgn2 ( NM_001025624.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001020795.1 Rattus norvegicus high mobility group nucleosomal binding domain 2 (Hmgn2), mRNA.

Price & Availability↑

CloneID	ORa07672
Clone ID Related Accession (Same CDS sequence)	NM_001025624.2
Accession Version	NM_001025624.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 273bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Rattus norvegicus(Norway rat)
Product	non-histone chromosomal protein HMG-17
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB614313.1 and BC099815.1. On Dec 23, 2009 this sequence version replaced NM_001025624.1. ##Evidence-Data-START## Transcript exon combination :: FQ220601.1, FQ219745.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGCCCAAAA GAAAGGCTGA AGGGGATGCT AAAGGAGACA AAGCCAAGGT GAAGGACGAG 
CCACAGAGAA GATCTGCAAG GTTGTCTGCT AAACCTGCTC CTCCAAAGCC AGAGCCCAAG 
CCTAAAAAGG CCCCTGCAAA GAAGGGAGAG AAGGTACCCA AGGGGAAGAA GGGGAAAGCG 
GATGCTGGTA AGGATGCGAA TAATCCTGCA GAAAACGGAG ATGCCAAAAC AGACCAGGCA 
CAGAAAGCGG ACGGTGCTGG AGATGCCAAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001020795.1
CDS	157..429
Translation	MPKRKAEGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKDANNPAENGDAKTDQAQKADGAGDAK

Target ORF information:

RefSeq Version	NM_001025624.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus high mobility group nucleosomal binding domain 2 (Hmgn2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001025624.2

ORF Insert Sequence:

ATGCCCAAAA GAAAGGCTGA AGGGGATGCT AAAGGAGACA AAGCCAAGGT GAAGGACGAG 
CCACAGAGAA GATCTGCAAG GTTGTCTGCT AAACCTGCTC CTCCAAAGCC AGAGCCCAAG 
CCTAAAAAGG CCCCTGCAAA GAAGGGAGAG AAGGTACCCA AGGGGAAGAA GGGGAAAGCG 
GATGCTGGTA AGGATGCGAA TAATCCTGCA GAAAACGGAG ATGCCAAAAC AGACCAGGCA 
CAGAAAGCGG ACGGTGCTGG AGATGCCAAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A model for the molecular underpinnings of tooth defects in Axenfeld-Rieger syndrome.
Human molecular genetics23(1)194-208(2014 Jan)
Li X,Venugopalan SR,Cao H,Pinho FO,Paine ML,Snead ML,Semina EV,Amendt BA

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Molecular cell46(5)674-90(2012 Jun)
Baltz AG,Munschauer M,Schwanh?usser B,Vasile A,Murakawa Y,Schueler M,Youngs N,Penfold-Brown D,Drew K,Milek M,Wyler E,Bonneau R,Selbach M,Dieterich C,Landthaler M

Effects of HMGN variants on the cellular transcription profile.
Nucleic acids research39(10)4076-87(2011 May)
Rochman M,Taher L,Kurahashi T,Cherukuri S,Uversky VN,Landsman D,Ovcharenko I,Bustin M

HMGN2: a novel antimicrobial effector molecule of human mononuclear leukocytes?
Journal of leukocyte biology78(5)1136-41(2005 Nov)
Feng Y,Huang N,Wu Q,Wang B

Cytokine-induced down-regulation of zfm1/splicing factor-1 promotes smooth muscle cell proliferation.
The Journal of biological chemistry277(8)6582-9(2002 Feb)
Cattaruzza M,Sch?fer K,Hecker M