IL6 cDNA ORF clone, Ochotona princeps(American pika)

Gene
Clones
gRNAs

Summary

Gene Symbol	IL6
Entrez Gene ID	101531329
Full Name	interleukin 6
Gene Type	protein-coding
Organism	Ochotona princeps(American pika)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001310092.1	NP_001297021.1	interleukin-6 precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Convergent evolution of IL-6 in two leporids (Oryctolagus and Pentalagus) originated an extended protein.
Neves F, Abrantes J, Pinheiro A, Almeida T, Costa PP, Esteves PJ
Immunogenetics66(9-10)589-95(2014 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following IL6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IL6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OOc38329	NM_001310092.1 Latest version!	Ochotona princeps interleukin 6 (IL6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$174.30 $249.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IL6 ( NM_001310092.1 ) cDNA ORF clone, Ochotona princeps(American pika) -> NP_001297021.1 Ochotona princeps interleukin 6 (IL6), mRNA.

Price & Availability↑

CloneID	OOc38329
Clone ID Related Accession (Same CDS sequence)	NM_001310092.1
Accession Version	NM_001310092.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 651bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-08-19
Organism	Ochotona princeps(American pika)
Product	interleukin-6 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from KJ939518.1. On Jun 26, 2015 this sequence version replaced XM_004582561.2. ##Evidence-Data-START## Transcript exon combination :: KJ939518.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN02086455 [ECO:0000350] ##Evidence-Data-END##

ATGAACTCCG TCTTCGCAAG CGCCCTCCGT CCAGCTCCCG TGGGCTTCGC GCTGGGGCTG 
CTCCTCGTGG TGGCCACTGC CTTCCCCACT GCTCCTTCAG TTTCCATGAA AGAAGAGCCC 
CAAGGTGGTG CTACCTCAGA TAAACCCTTC ACGCCGGTCA AAATTGAATC TACCATTTCT 
TACATCCTCA TGAAGATCTC CGATATCAGA AAGAAGATGT GCAACTATGA CGCCAACTGC 
CTGGATTGCA AGCAAGTACT GTCAGATGTC AACCTGACCC TTCCACAGCT GACAGAAAGA 
GACGGATGCT TCCCGTCGGC ACCAAATCAG GAGATTTGCC TGATGAGAAT CACTGCTGGC 
CTTTTGGAGT TTGAGATTTA CCTAAAGCAC CTTCAGAACA AGTTCAAGAG TGATGAGGAA 
AACAACAACA TGGACATTGT GCTGCAGAAC AGTCAAACCC TGGTCAAGAC CCTGAGGCCA 
AAGGTCAAGA CTACTGAAGA AGCACCCACT CTTGAGCCAG CCACTTTGAC CAGCCTAAAG 
GAGAATATGC AGCTGAAGGA GCAGTGGCGA AGGACACAGA CAATCCACTA CATCCTGTGT 
GGCCTCAAGG ACTTCCTGGA GTTCACCCTG CGTGCGGTGC GCCTGATGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001297021.1
CDS	1..651
Translation	MNSVFASALRPAPVGFALGLLLVVATAFPTAPSVSMKEEPQGGATSDKPFTPVKIESTISYILMKISDIRKKMCNYDANCLDCKQVLSDVNLTLPQLTERDGCFPSAPNQEICLMRITAGLLEFEIYLKHLQNKFKSDEENNNMDIVLQNSQTLVKTLRPKVKTTEEAPTLEPATLTSLKENMQLKEQWRRTQTIHYILCGLKDFLEFTLRAVRLM

Target ORF information:

RefSeq Version	NM_001310092.1
Organism	Ochotona princeps(American pika)
Definition	Ochotona princeps interleukin 6 (IL6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001310092.1

ORF Insert Sequence:

ATGAACTCCG TCTTCGCAAG CGCCCTCCGT CCAGCTCCCG TGGGCTTCGC GCTGGGGCTG 
CTCCTCGTGG TGGCCACTGC CTTCCCCACT GCTCCTTCAG TTTCCATGAA AGAAGAGCCC 
CAAGGTGGTG CTACCTCAGA TAAACCCTTC ACGCCGGTCA AAATTGAATC TACCATTTCT 
TACATCCTCA TGAAGATCTC CGATATCAGA AAGAAGATGT GCAACTATGA CGCCAACTGC 
CTGGATTGCA AGCAAGTACT GTCAGATGTC AACCTGACCC TTCCACAGCT GACAGAAAGA 
GACGGATGCT TCCCGTCGGC ACCAAATCAG GAGATTTGCC TGATGAGAAT CACTGCTGGC 
CTTTTGGAGT TTGAGATTTA CCTAAAGCAC CTTCAGAACA AGTTCAAGAG TGATGAGGAA 
AACAACAACA TGGACATTGT GCTGCAGAAC AGTCAAACCC TGGTCAAGAC CCTGAGGCCA 
AAGGTCAAGA CTACTGAAGA AGCACCCACT CTTGAGCCAG CCACTTTGAC CAGCCTAAAG 
GAGAATATGC AGCTGAAGGA GCAGTGGCGA AGGACACAGA CAATCCACTA CATCCTGTGT 
GGCCTCAAGG ACTTCCTGGA GTTCACCCTG CGTGCGGTGC GCCTGATGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Convergent evolution of IL-6 in two leporids (Oryctolagus and Pentalagus) originated an extended protein.
Immunogenetics66(9-10)589-95(2014 Oct)
Neves F,Abrantes J,Pinheiro A,Almeida T,Costa PP,Esteves PJ