Spz1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Spz1
Entrez Gene ID	79401
Full Name	spermatogenic leucine zipper 1
Synonyms	1700027M20Rik,AI429130
General protein information	Preferred Names spermatogenic leucine zipper 1 Names spermatogenic leucine zipper protein 1 bhlh-zip transcription factor SPZ1 spermatogenic Zip 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 13 Map Location: 13\|13 C3

mRNA and Protein(s)

mRNA	Protein	Name
NM_030237.3	NP_084513.3	spermatogenic leucine zipper protein 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	SPZ1	NP_115956.3
Pan troglodytes (chimpanzee)	SPZ1	XP_001136809.2
	SPZ1	XP_001109987.1
Bos taurus (cattle)	SPZ1	NP_001035630.1
Mus musculus (house mouse)	Spz1	NP_084513.3
Canis lupus familiaris (dog)	SPZ1	XP_546045.1
Rattus norvegicus (Norway rat)	Spz1	NP_001019468.1

Gene Ontology
Bibliography

Related articles in PubMed

A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H
Developmental cell17(6)836-48(2009 Dec)

bHLH-zip transcription factor Spz1 mediates mitogen-activated protein kinase cell proliferation, transformation, and tumorigenesis.
Hsu SH, Hsieh-Li HM, Huang HY, Huang PH, Li H
Cancer research65(10)4041-50(2005 May)

Identification of the spermatogenic zip protein Spz1 as a putative protein phosphatase-1 (PP1) regulatory protein that specifically binds the PP1cgamma2 splice variant in mouse testis.
Hrabchak C, Varmuza S
The Journal of biological chemistry279(35)37079-86(2004 Aug)

Dysfunctional spermatogenesis in transgenic mice overexpressing bHLH-Zip transcription factor, Spz1.
Hsu SH, Hsieh-Li HM, Li H
Experimental cell research294(1)185-98(2004 Mar)

Spz1, a novel bHLH-Zip protein, is specifically expressed in testis.
Hsu SH, Shyu HW, Hsieh-Li HM, Li H
Mechanisms of development100(2)177-87(2001 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the interaction between Spz1 and PP1cgamma2 may be required for proper regulation of spermatogenesis and fertility in males
Title: Identification of the spermatogenic zip protein Spz1 as a putative protein phosphatase-1 (PP1) regulatory protein that specifically binds the PP1cgamma2 splice variant in mouse testis.

Spz1 has a regulatory role during spermatogenesis.
Title: Dysfunctional spermatogenesis in transgenic mice overexpressing bHLH-Zip transcription factor, Spz1.

The following Spz1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Spz1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu58594	NM_030237.3 Latest version!	Mus musculus spermatogenic leucine zipper 1 (Spz1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Spz1 ( NM_030237.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_084513.3 Mus musculus spermatogenic leucine zipper 1 (Spz1), mRNA.

Price & Availability↑

CloneID	OMu58594
Clone ID Related Accession (Same CDS sequence)	NM_030237.3
Accession Version	NM_030237.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1137bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Mus musculus(house mouse)
Product	spermatogenic leucine zipper protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC154363.2, AK006437.2 and AF271697.1. On Jun 30, 2009 this sequence version replaced NM_030237.2. COMPLETENESS: complete on the 3' end.

ATGTCGGACA CAGACAACTC AGCGGAGATG CCCGCCCGGT GTCCATCTCC TAACCCTGCT 
CCTGGTGCTA AGCAAGAACC ACCGAACTCT GGGATCACCA TTTCCCTCCT TGAAATCGGA 
TCACTCCCCA CTGTCTGCTA CCACTCCTTC CCACCACCAA AGAATAGCAT CTGTCCAGTA 
GAGAAAAGAG GGAGGGTACA GAAATTTAGC AATCTCTTAA AAGACGTTAA GGATGTTCTC 
AAAAACATAG CAGGCGTTGA AGAGAAGTCT ACAGTTGGGG AGCCTTTTGA TGATGCCTAT 
ATTCCTGAAG ACCTGTCAGA ACTTAACGTC AGAGGTGTTG AGAAGAAAAA TAAAATACGA 
TTTAAAGATG ATCTATTCAT TCATTTCGAC CCAGAGAGAG AACAGAACAC AATGAAGCAG 
ATGTTATTGA AAAACCAGAG TGCTAAGAAC ATGGTACCAA AGTTTGCAAG GGACCTGTGC 
AATGCAGAAG AAACGAGAGG CTTCGACGGC ATGCTGCTGA GCGTGAAAAG ACCGCGGAAT 
GGATCCCTTC ACCTTCGCGG AGAGTACAGA AAACTCAGGA ACAACATGGA GCAGTTACTG 
CAGGAAGCAG ATCACTGGAG TAAACAGCAT AACGAACTCA GCGAACTAAT GAGGTCATAT 
CAGGAATGCC AGAACGAAAC CCAAGAAACT ACTGACAAGG ATCGAGCCTG TTTGCAAAAC 
CAACCCAACA ATGGGCTATC CACCAAGCAG AAGCTGGAGG AGCAGGTGAA GAAGCTAAGC 
CATGACACCC ACGCGCTGCA TTTGATCGCA GCCCTGCTAG AGAATGAATG TCAGGTCCTA 
CAACAGAGGG TAGACATCCT CAAGGATTTC CATCTCCACG AAGCGGGACT GGGGCACGAG 
AAGCCTTTGC AGATGTCCTG TGAGCAGGAC AAGAAATGTC CGAAGTTAGC GGAAGCAGAC 
AAGACGGACG CTTTCAAGCA TACCACGAGG GCAACGGAAG GCACGATTAG GAAACCGAAG 
ATCCTCAGGA GCCCGGATGT TTGCTTTACT AAGAAGGCTC GGAATAACCG CTTCAACGCC 
CGTGTTGCAA AGAAATCTCT GGTGGGGAAA AGGAGAACCG TTAGCAGCTT TCGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_084513.3
CDS	267..1403
Translation	MSDTDNSAEMPARCPSPNPAPGAKQEPPNSGITISLLEIGSLPTVCYHSFPPPKNSICPVEKRGRVQKFSNLLKDVKDVLKNIAGVEEKSTVGEPFDDAYIPEDLSELNVRGVEKKNKIRFKDDLFIHFDPEREQNTMKQMLLKNQSAKNMVPKFARDLCNAEETRGFDGMLLSVKRPRNGSLHLRGEYRKLRNNMEQLLQEADHWSKQHNELSELMRSYQECQNETQETTDKDRACLQNQPNNGLSTKQKLEEQVKKLSHDTHALHLIAALLENECQVLQQRVDILKDFHLHEAGLGHEKPLQMSCEQDKKCPKLAEADKTDAFKHTTRATEGTIRKPKILRSPDVCFTKKARNNRFNARVAKKSLVGKRRTVSSFR

Target ORF information:

RefSeq Version	NM_030237.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus spermatogenic leucine zipper 1 (Spz1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_030237.3

ORF Insert Sequence:

ATGTCGGACA CAGACAACTC AGCGGAGATG CCCGCCCGGT GTCCATCTCC TAACCCTGCT 
CCTGGTGCTA AGCAAGAACC ACCGAACTCT GGGATCACCA TTTCCCTCCT TGAAATCGGA 
TCACTCCCCA CTGTCTGCTA CCACTCCTTC CCACCACCAA AGAATAGCAT CTGTCCAGTA 
GAGAAAAGAG GGAGGGTACA GAAATTTAGC AATCTCTTAA AAGACGTTAA GGATGTTCTC 
AAAAACATAG CAGGCGTTGA AGAGAAGTCT ACAGTTGGGG AGCCTTTTGA TGATGCCTAT 
ATTCCTGAAG ACCTGTCAGA ACTTAACGTC AGAGGTGTTG AGAAGAAAAA TAAAATACGA 
TTTAAAGATG ATCTATTCAT TCATTTCGAC CCAGAGAGAG AACAGAACAC AATGAAGCAG 
ATGTTATTGA AAAACCAGAG TGCTAAGAAC ATGGTACCAA AGTTTGCAAG GGACCTGTGC 
AATGCAGAAG AAACGAGAGG CTTCGACGGC ATGCTGCTGA GCGTGAAAAG ACCGCGGAAT 
GGATCCCTTC ACCTTCGCGG AGAGTACAGA AAACTCAGGA ACAACATGGA GCAGTTACTG 
CAGGAAGCAG ATCACTGGAG TAAACAGCAT AACGAACTCA GCGAACTAAT GAGGTCATAT 
CAGGAATGCC AGAACGAAAC CCAAGAAACT ACTGACAAGG ATCGAGCCTG TTTGCAAAAC 
CAACCCAACA ATGGGCTATC CACCAAGCAG AAGCTGGAGG AGCAGGTGAA GAAGCTAAGC 
CATGACACCC ACGCGCTGCA TTTGATCGCA GCCCTGCTAG AGAATGAATG TCAGGTCCTA 
CAACAGAGGG TAGACATCCT CAAGGATTTC CATCTCCACG AAGCGGGACT GGGGCACGAG 
AAGCCTTTGC AGATGTCCTG TGAGCAGGAC AAGAAATGTC CGAAGTTAGC GGAAGCAGAC 
AAGACGGACG CTTTCAAGCA TACCACGAGG GCAACGGAAG GCACGATTAG GAAACCGAAG 
ATCCTCAGGA GCCCGGATGT TTGCTTTACT AAGAAGGCTC GGAATAACCG CTTCAACGCC 
CGTGTTGCAA AGAAATCTCT GGTGGGGAAA AGGAGAACCG TTAGCAGCTT TCGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Developmental cell17(6)836-48(2009 Dec)
Yokoyama S,Ito Y,Ueno-Kudoh H,Shimizu H,Uchibe K,Albini S,Mitsuoka K,Miyaki S,Kiso M,Nagai A,Hikata T,Osada T,Fukuda N,Yamashita S,Harada D,Mezzano V,Kasai M,Puri PL,Hayashizaki Y,Okado H,Hashimoto M,Asahara H

bHLH-zip transcription factor Spz1 mediates mitogen-activated protein kinase cell proliferation, transformation, and tumorigenesis.
Cancer research65(10)4041-50(2005 May)
Hsu SH,Hsieh-Li HM,Huang HY,Huang PH,Li H

Identification of the spermatogenic zip protein Spz1 as a putative protein phosphatase-1 (PP1) regulatory protein that specifically binds the PP1cgamma2 splice variant in mouse testis.
The Journal of biological chemistry279(35)37079-86(2004 Aug)
Hrabchak C,Varmuza S

Dysfunctional spermatogenesis in transgenic mice overexpressing bHLH-Zip transcription factor, Spz1.
Experimental cell research294(1)185-98(2004 Mar)
Hsu SH,Hsieh-Li HM,Li H

Spz1, a novel bHLH-Zip protein, is specifically expressed in testis.
Mechanisms of development100(2)177-87(2001 Feb)
Hsu SH,Shyu HW,Hsieh-Li HM,Li H