Glipr1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Glipr1
Entrez Gene ID	73690
Full Name	GLI pathogenesis-related 1 (glioma)
Synonyms	2410114O14Rik,RTVP-1,RTVP1,mRTVP-1
General protein information	Preferred Names GLI pathogenesis-related 1 (glioma) Names glioma pathogenesis-related protein 1 gliPR 1 related to testes-specific, vespid, and pathogenesis proteins
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 10 Map Location: 10\|10 D2

mRNA and Protein(s)

mRNA	Protein	Name
XM_006514218.4	XP_006514281.1	glioma pathogenesis-related protein 1 isoform X1
XM_006514217.3	XP_006514280.1	glioma pathogenesis-related protein 1 isoform X1
XM_006514218.3	XP_006514281.1	glioma pathogenesis-related protein 1 isoform X1
XM_006514217.4	XP_006514280.1	glioma pathogenesis-related protein 1 isoform X1
NM_028608.3	NP_082884.1	glioma pathogenesis-related protein 1 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	GLIPR1	XP_522475.2
	GLIPR1	XP_001117594.1
Gallus gallus (chicken)	GLIPR1L	NP_001025914.2
Danio rerio (zebrafish)	LOC101886846	XP_005164521.1
Rattus norvegicus (Norway rat)	Glipr1	NP_001011987.1
Gallus gallus (chicken)	GLIPR1	XP_004937633.1
Bos taurus (cattle)	GLIPR1	NP_001070452.1
Homo sapiens (human)	GLIPR1	NP_006842.2
Canis lupus familiaris (dog)	GLIPR1	XP_531682.1
Mus musculus (house mouse)	Glipr1	NP_082884.1

Gene Ontology
Bibliography

Related articles in PubMed

GLI pathogenesis-related 1 functions as a tumor-suppressor in lung cancer.
Sheng X, Bowen N, Wang Z
Molecular cancer1525(2016 Mar)

Combined therapeutic effects of adenoviral vector-mediated GLIPR1 gene therapy and radiotherapy in prostate and bladder cancer models.
Fujita T, Satoh T, Timme TL, Hirayama T, Zhu JX, Kusaka N, Naruishi K, Yang G, Goltsov A, Wang J, Vlachaki MT, Teh BS, Brian Butler E, Thompson TC
Urologic oncology32(2)92-100(2014 Feb)

GLIPR1 suppresses prostate cancer development through targeted oncoprotein destruction.
Li L, Ren C, Yang G, Fattah EA, Goltsov AA, Kim SM, Lee JS, Park S, Demayo FJ, Ittmann MM, Troncoso P, Thompson TC
Cancer research71(24)7694-704(2011 Dec)

Genetic variations regulate alternative splicing in the 5' untranslated regions of the mouse glioma-associated oncogene 1, Gli1.
Palaniswamy R, Teglund S, Lauth M, Zaphiropoulos PG, Shimokawa T
BMC molecular biology1132(2010 Apr)

Identification of transcripts with enriched expression in the developing and adult pancreas.
Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJ, Marra MA, Helgason CD
Genome biology9(6)R99(2008)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study reveals a novel pathway that PRMT5/WDR77 regulates GLIPR1 expression to control lung cancer cell growth.
Title: GLI pathogenesis-related 1 functions as a tumor-suppressor in lung cancer.

Data indicate that combining adenoviral vector-mediated GLIPR1 gene therap (AdGLIPR1) with radiotherapy may achieve additive or synergistic tumor control in selected prostate and bladder tumors.
Title: Combined therapeutic effects of adenoviral vector-mediated GLIPR1 gene therapy and radiotherapy in prostate and bladder cancer models.

The genetic variation is a key determining factor for the alternative splicing events in the Gli1 5' UTRs, which have functional implications on translational efficiency.
Title: Genetic variations regulate alternative splicing in the 5' untranslated regions of the mouse glioma-associated oncogene 1, Gli1.

Identification of a novel mouse gene, mRTVP-1, as a p53 target gene. The mRTVP-1 protein has 255 amino acids and differs from the human RTVP-1 protein by two short in-frame deletions of two and nine amino acids. (mRTVP-1)
Title: mRTVP-1, a novel p53 target gene with proapoptotic activities.

The following Glipr1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Glipr1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu05852	NM_028608.3 Latest version!	Mus musculus GLI pathogenesis-related 1 (glioma) (Glipr1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
OMu44885	XM_006514217.4 Latest version!	Mus musculus GLI pathogenesis-related 1 (glioma) (Glipr1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu44885	XM_006514218.4 Latest version!	Mus musculus GLI pathogenesis-related 1 (glioma) (Glipr1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OMu44885	XM_006514218.3	Mus musculus GLI pathogenesis-related 1 (glioma) (Glipr1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu44885	XM_006514217.3	Mus musculus GLI pathogenesis-related 1 (glioma) (Glipr1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Glipr1 ( XM_006514217.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006514280.1 Mus musculus GLI pathogenesis-related 1 (glioma) (Glipr1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu44885
Clone ID Related Accession (Same CDS sequence)	XM_006514218.4 , XM_006514217.3 , XM_006514218.3 , XM_006514217.4
Accession Version	XM_006514217.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 813bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	glioma pathogenesis-related protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000076.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006514217.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGGTCA TCCTTGCTGT GATAGTCTGG ATGGCTTCGT CTGTGTCTAG TTCTTCATTT 
ACAGCAAGCA CTTTGCCAGA TATAACAAAC GAGGACTTCA TTAAAGAATG TGTTCAAGTT 
CACAACCAGC TTCGGTCAAA AGTGAGTCCA CCAGCCCGGA ATATGCTGTA CATGTCTTGG 
GACCCAAAAC TAGCCCAAAT TGCAAAAGCA TGGACAAAAT CTTGTGAATT TAAACACAAC 
CCACAGCTGC ATTCACGGAT ACACCCAAAT TTCACCGCCC TGGGAGAGAA TATCTGGCTT 
GGCTCTCTAT CCATCTTTTC AGTATCCTCA GCCATCTCTG CCTGGTATGA AGAAATTAAG 
CACTATGACT TCAGCACTAG GAAATGTAGA CATGTCTGTG GCCATTATAC TCAGGTTGTT 
TGGGCAGACA GTTACAAACT TGGCTGTGCA GTGCAACTTT GCCCTAATGG AGCAAATTTT 
ATATGCGACT ATGGACCAGC AGGAAATTAC CCAACGTGGC CATATAAGCA AGGAGCCACG 
TGCAGTGATT GCCCAAAAGA TGACAAGTGT CTCAACAGTC TCTGCATTAA CCCACGACGA 
GACCAGGTCT CACGTATGTA TGCAAACCTT AAGCTGTTTT CCCGGGGCAC TATGCAGGCT 
GGGTTAGCAC AGCATGGGAA ACTGAGTCCA CTCTTCTTCG TTTCACAGGT TACTACTCTG 
TCGATTATCC AGACTGGCCT ATATACCTGC GTAACAGATA CACATCTCTC TTTCTCATTG 
CTAAGTCGGT TCTCCTATTA CTGTCTGTTA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006514280.1
CDS	235..1047
Translation	MQVILAVIVWMASSVSSSSFTASTLPDITNEDFIKECVQVHNQLRSKVSPPARNMLYMSWDPKLAQIAKAWTKSCEFKHNPQLHSRIHPNFTALGENIWLGSLSIFSVSSAISAWYEEIKHYDFSTRKCRHVCGHYTQVVWADSYKLGCAVQLCPNGANFICDYGPAGNYPTWPYKQGATCSDCPKDDKCLNSLCINPRRDQVSRMYANLKLFSRGTMQAGLAQHGKLSPLFFVSQVTTLSIIQTGLYTCVTDTHLSFSLLSRFSYYCLL

Target ORF information:

RefSeq Version	XM_006514217.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus GLI pathogenesis-related 1 (glioma) (Glipr1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006514217.3

ORF Insert Sequence:

ATGCAGGTCA TCCTTGCTGT GATAGTCTGG ATGGCTTCGT CTGTGTCTAG TTCTTCATTT 
ACAGCAAGCA CTTTGCCAGA TATAACAAAC GAGGACTTCA TTAAAGAATG TGTTCAAGTT 
CACAACCAGC TTCGGTCAAA AGTGAGTCCA CCAGCCCGGA ATATGCTGTA CATGTCTTGG 
GACCCAAAAC TAGCCCAAAT TGCAAAAGCA TGGACAAAAT CTTGTGAATT TAAACACAAC 
CCACAGCTGC ATTCACGGAT ACACCCAAAT TTCACCGCCC TGGGAGAGAA TATCTGGCTT 
GGCTCTCTAT CCATCTTTTC AGTATCCTCA GCCATCTCTG CCTGGTATGA AGAAATTAAG 
CACTATGACT TCAGCACTAG GAAATGTAGA CATGTCTGTG GCCATTATAC TCAGGTTGTT 
TGGGCAGACA GTTACAAACT TGGCTGTGCA GTGCAACTTT GCCCTAATGG AGCAAATTTT 
ATATGCGACT ATGGACCAGC AGGAAATTAC CCAACGTGGC CATATAAGCA AGGAGCCACG 
TGCAGTGATT GCCCAAAAGA TGACAAGTGT CTCAACAGTC TCTGCATTAA CCCACGACGA 
GACCAGGTCT CACGTATGTA TGCAAACCTT AAGCTGTTTT CCCGGGGCAC TATGCAGGCT 
GGGTTAGCAC AGCATGGGAA ACTGAGTCCA CTCTTCTTCG TTTCACAGGT TACTACTCTG 
TCGATTATCC AGACTGGCCT ATATACCTGC GTAACAGATA CACATCTCTC TTTCTCATTG 
CTAAGTCGGT TCTCCTATTA CTGTCTGTTA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Glipr1 ( XM_006514218.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006514281.1 Mus musculus GLI pathogenesis-related 1 (glioma) (Glipr1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu44885
Clone ID Related Accession (Same CDS sequence)	XM_006514218.4 , XM_006514217.3 , XM_006514218.3 , XM_006514217.4
Accession Version	XM_006514218.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 813bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	glioma pathogenesis-related protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000076.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006514218.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGGTCA TCCTTGCTGT GATAGTCTGG ATGGCTTCGT CTGTGTCTAG TTCTTCATTT 
ACAGCAAGCA CTTTGCCAGA TATAACAAAC GAGGACTTCA TTAAAGAATG TGTTCAAGTT 
CACAACCAGC TTCGGTCAAA AGTGAGTCCA CCAGCCCGGA ATATGCTGTA CATGTCTTGG 
GACCCAAAAC TAGCCCAAAT TGCAAAAGCA TGGACAAAAT CTTGTGAATT TAAACACAAC 
CCACAGCTGC ATTCACGGAT ACACCCAAAT TTCACCGCCC TGGGAGAGAA TATCTGGCTT 
GGCTCTCTAT CCATCTTTTC AGTATCCTCA GCCATCTCTG CCTGGTATGA AGAAATTAAG 
CACTATGACT TCAGCACTAG GAAATGTAGA CATGTCTGTG GCCATTATAC TCAGGTTGTT 
TGGGCAGACA GTTACAAACT TGGCTGTGCA GTGCAACTTT GCCCTAATGG AGCAAATTTT 
ATATGCGACT ATGGACCAGC AGGAAATTAC CCAACGTGGC CATATAAGCA AGGAGCCACG 
TGCAGTGATT GCCCAAAAGA TGACAAGTGT CTCAACAGTC TCTGCATTAA CCCACGACGA 
GACCAGGTCT CACGTATGTA TGCAAACCTT AAGCTGTTTT CCCGGGGCAC TATGCAGGCT 
GGGTTAGCAC AGCATGGGAA ACTGAGTCCA CTCTTCTTCG TTTCACAGGT TACTACTCTG 
TCGATTATCC AGACTGGCCT ATATACCTGC GTAACAGATA CACATCTCTC TTTCTCATTG 
CTAAGTCGGT TCTCCTATTA CTGTCTGTTA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006514281.1
CDS	343..1155
Translation	MQVILAVIVWMASSVSSSSFTASTLPDITNEDFIKECVQVHNQLRSKVSPPARNMLYMSWDPKLAQIAKAWTKSCEFKHNPQLHSRIHPNFTALGENIWLGSLSIFSVSSAISAWYEEIKHYDFSTRKCRHVCGHYTQVVWADSYKLGCAVQLCPNGANFICDYGPAGNYPTWPYKQGATCSDCPKDDKCLNSLCINPRRDQVSRMYANLKLFSRGTMQAGLAQHGKLSPLFFVSQVTTLSIIQTGLYTCVTDTHLSFSLLSRFSYYCLL

Target ORF information:

RefSeq Version	XM_006514218.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus GLI pathogenesis-related 1 (glioma) (Glipr1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006514218.3

ORF Insert Sequence:

ATGCAGGTCA TCCTTGCTGT GATAGTCTGG ATGGCTTCGT CTGTGTCTAG TTCTTCATTT 
ACAGCAAGCA CTTTGCCAGA TATAACAAAC GAGGACTTCA TTAAAGAATG TGTTCAAGTT 
CACAACCAGC TTCGGTCAAA AGTGAGTCCA CCAGCCCGGA ATATGCTGTA CATGTCTTGG 
GACCCAAAAC TAGCCCAAAT TGCAAAAGCA TGGACAAAAT CTTGTGAATT TAAACACAAC 
CCACAGCTGC ATTCACGGAT ACACCCAAAT TTCACCGCCC TGGGAGAGAA TATCTGGCTT 
GGCTCTCTAT CCATCTTTTC AGTATCCTCA GCCATCTCTG CCTGGTATGA AGAAATTAAG 
CACTATGACT TCAGCACTAG GAAATGTAGA CATGTCTGTG GCCATTATAC TCAGGTTGTT 
TGGGCAGACA GTTACAAACT TGGCTGTGCA GTGCAACTTT GCCCTAATGG AGCAAATTTT 
ATATGCGACT ATGGACCAGC AGGAAATTAC CCAACGTGGC CATATAAGCA AGGAGCCACG 
TGCAGTGATT GCCCAAAAGA TGACAAGTGT CTCAACAGTC TCTGCATTAA CCCACGACGA 
GACCAGGTCT CACGTATGTA TGCAAACCTT AAGCTGTTTT CCCGGGGCAC TATGCAGGCT 
GGGTTAGCAC AGCATGGGAA ACTGAGTCCA CTCTTCTTCG TTTCACAGGT TACTACTCTG 
TCGATTATCC AGACTGGCCT ATATACCTGC GTAACAGATA CACATCTCTC TTTCTCATTG 
CTAAGTCGGT TCTCCTATTA CTGTCTGTTA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Glipr1 ( NM_028608.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_082884.1 Mus musculus GLI pathogenesis-related 1 (glioma) (Glipr1), mRNA.

Price & Availability↑

CloneID	OMu05852
Clone ID Related Accession (Same CDS sequence)	NM_028608.3
Accession Version	NM_028608.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 768bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-03
Organism	Mus musculus(house mouse)
Product	glioma pathogenesis-related protein 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB869923.1, BC098231.1 and BY540964.1. On Apr 9, 2009 this sequence version replaced NM_028608.2. ##Evidence-Data-START## Transcript exon combination :: BC098231.1, AK137557.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164134, SAMN01164135 [ECO:0000348] ##Evidence-Data-END##

ATGCAGGTCA TCCTTGCTGT GATAGTCTGG ATGGCTTCGT CTGTGTCTAG TTCTTCATTT 
ACAGCAAGCA CTTTGCCAGA TATAACAAAC GAGGACTTCA TTAAAGAATG TGTTCAAGTT 
CACAACCAGC TTCGGTCAAA AGTGAGTCCA CCAGCCCGGA ATATGCTGTA CATGTCTTGG 
GACCCAAAAC TAGCCCAAAT TGCAAAAGCA TGGACAAAAT CTTGTGAATT TAAACACAAC 
CCACAGCTGC ATTCACGGAT ACACCCAAAT TTCACCGCCC TGGGAGAGAA TATCTGGCTT 
GGCTCTCTAT CCATCTTTTC AGTATCCTCA GCCATCTCTG CCTGGTATGA AGAAATTAAG 
CACTATGACT TCAGCACTAG GAAATGTAGA CATGTCTGTG GCCATTATAC TCAGGTTGTT 
TGGGCAGACA GTTACAAACT TGGCTGTGCA GTGCAACTTT GCCCTAATGG AGCAAATTTT 
ATATGCGACT ATGGACCAGC AGGAAATTAC CCAACGTGGC CATATAAGCA AGGAGCCACG 
TGCAGTGATT GCCCAAAAGA TGACAAGTGT CTCAACAGTC TCTGCATTAA CCCACGACGA 
GACCAGGTCT CACGTTACTA CTCTGTCGAT TATCCAGACT GGCCTATATA CCTGCGTAAC 
AGATACACAT CTCTCTTTCT CATTGCTAAG TCGGTTCTCC TATTACTGTC TGTTATAATT 
ACCATCTGGG TAAAGCACAA ATATCCTAAC TTGGTTCTTT TGGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_082884.1
CDS	234..1001
Translation	MQVILAVIVWMASSVSSSSFTASTLPDITNEDFIKECVQVHNQLRSKVSPPARNMLYMSWDPKLAQIAKAWTKSCEFKHNPQLHSRIHPNFTALGENIWLGSLSIFSVSSAISAWYEEIKHYDFSTRKCRHVCGHYTQVVWADSYKLGCAVQLCPNGANFICDYGPAGNYPTWPYKQGATCSDCPKDDKCLNSLCINPRRDQVSRYYSVDYPDWPIYLRNRYTSLFLIAKSVLLLLSVIITIWVKHKYPNLVLLD

Target ORF information:

RefSeq Version	NM_028608.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus GLI pathogenesis-related 1 (glioma) (Glipr1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_028608.3

ORF Insert Sequence:

ATGCAGGTCA TCCTTGCTGT GATAGTCTGG ATGGCTTCGT CTGTGTCTAG TTCTTCATTT 
ACAGCAAGCA CTTTGCCAGA TATAACAAAC GAGGACTTCA TTAAAGAATG TGTTCAAGTT 
CACAACCAGC TTCGGTCAAA AGTGAGTCCA CCAGCCCGGA ATATGCTGTA CATGTCTTGG 
GACCCAAAAC TAGCCCAAAT TGCAAAAGCA TGGACAAAAT CTTGTGAATT TAAACACAAC 
CCACAGCTGC ATTCACGGAT ACACCCAAAT TTCACCGCCC TGGGAGAGAA TATCTGGCTT 
GGCTCTCTAT CCATCTTTTC AGTATCCTCA GCCATCTCTG CCTGGTATGA AGAAATTAAG 
CACTATGACT TCAGCACTAG GAAATGTAGA CATGTCTGTG GCCATTATAC TCAGGTTGTT 
TGGGCAGACA GTTACAAACT TGGCTGTGCA GTGCAACTTT GCCCTAATGG AGCAAATTTT 
ATATGCGACT ATGGACCAGC AGGAAATTAC CCAACGTGGC CATATAAGCA AGGAGCCACG 
TGCAGTGATT GCCCAAAAGA TGACAAGTGT CTCAACAGTC TCTGCATTAA CCCACGACGA 
GACCAGGTCT CACGTTACTA CTCTGTCGAT TATCCAGACT GGCCTATATA CCTGCGTAAC 
AGATACACAT CTCTCTTTCT CATTGCTAAG TCGGTTCTCC TATTACTGTC TGTTATAATT 
ACCATCTGGG TAAAGCACAA ATATCCTAAC TTGGTTCTTT TGGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Glipr1 ( XM_006514218.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006514281.1 Mus musculus GLI pathogenesis-related 1 (glioma) (Glipr1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu44885
Clone ID Related Accession (Same CDS sequence)	XM_006514218.4 , XM_006514217.3 , XM_006514218.3 , XM_006514217.4
Accession Version	XM_006514218.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 813bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	glioma pathogenesis-related protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000076.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006514218.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGGTCA TCCTTGCTGT GATAGTCTGG ATGGCTTCGT CTGTGTCTAG TTCTTCATTT 
ACAGCAAGCA CTTTGCCAGA TATAACAAAC GAGGACTTCA TTAAAGAATG TGTTCAAGTT 
CACAACCAGC TTCGGTCAAA AGTGAGTCCA CCAGCCCGGA ATATGCTGTA CATGTCTTGG 
GACCCAAAAC TAGCCCAAAT TGCAAAAGCA TGGACAAAAT CTTGTGAATT TAAACACAAC 
CCACAGCTGC ATTCACGGAT ACACCCAAAT TTCACCGCCC TGGGAGAGAA TATCTGGCTT 
GGCTCTCTAT CCATCTTTTC AGTATCCTCA GCCATCTCTG CCTGGTATGA AGAAATTAAG 
CACTATGACT TCAGCACTAG GAAATGTAGA CATGTCTGTG GCCATTATAC TCAGGTTGTT 
TGGGCAGACA GTTACAAACT TGGCTGTGCA GTGCAACTTT GCCCTAATGG AGCAAATTTT 
ATATGCGACT ATGGACCAGC AGGAAATTAC CCAACGTGGC CATATAAGCA AGGAGCCACG 
TGCAGTGATT GCCCAAAAGA TGACAAGTGT CTCAACAGTC TCTGCATTAA CCCACGACGA 
GACCAGGTCT CACGTATGTA TGCAAACCTT AAGCTGTTTT CCCGGGGCAC TATGCAGGCT 
GGGTTAGCAC AGCATGGGAA ACTGAGTCCA CTCTTCTTCG TTTCACAGGT TACTACTCTG 
TCGATTATCC AGACTGGCCT ATATACCTGC GTAACAGATA CACATCTCTC TTTCTCATTG 
CTAAGTCGGT TCTCCTATTA CTGTCTGTTA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006514281.1
CDS	361..1173
Translation	MQVILAVIVWMASSVSSSSFTASTLPDITNEDFIKECVQVHNQLRSKVSPPARNMLYMSWDPKLAQIAKAWTKSCEFKHNPQLHSRIHPNFTALGENIWLGSLSIFSVSSAISAWYEEIKHYDFSTRKCRHVCGHYTQVVWADSYKLGCAVQLCPNGANFICDYGPAGNYPTWPYKQGATCSDCPKDDKCLNSLCINPRRDQVSRMYANLKLFSRGTMQAGLAQHGKLSPLFFVSQVTTLSIIQTGLYTCVTDTHLSFSLLSRFSYYCLL

Target ORF information:

RefSeq Version	XM_006514218.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus GLI pathogenesis-related 1 (glioma) (Glipr1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006514218.4

ORF Insert Sequence:

ATGCAGGTCA TCCTTGCTGT GATAGTCTGG ATGGCTTCGT CTGTGTCTAG TTCTTCATTT 
ACAGCAAGCA CTTTGCCAGA TATAACAAAC GAGGACTTCA TTAAAGAATG TGTTCAAGTT 
CACAACCAGC TTCGGTCAAA AGTGAGTCCA CCAGCCCGGA ATATGCTGTA CATGTCTTGG 
GACCCAAAAC TAGCCCAAAT TGCAAAAGCA TGGACAAAAT CTTGTGAATT TAAACACAAC 
CCACAGCTGC ATTCACGGAT ACACCCAAAT TTCACCGCCC TGGGAGAGAA TATCTGGCTT 
GGCTCTCTAT CCATCTTTTC AGTATCCTCA GCCATCTCTG CCTGGTATGA AGAAATTAAG 
CACTATGACT TCAGCACTAG GAAATGTAGA CATGTCTGTG GCCATTATAC TCAGGTTGTT 
TGGGCAGACA GTTACAAACT TGGCTGTGCA GTGCAACTTT GCCCTAATGG AGCAAATTTT 
ATATGCGACT ATGGACCAGC AGGAAATTAC CCAACGTGGC CATATAAGCA AGGAGCCACG 
TGCAGTGATT GCCCAAAAGA TGACAAGTGT CTCAACAGTC TCTGCATTAA CCCACGACGA 
GACCAGGTCT CACGTATGTA TGCAAACCTT AAGCTGTTTT CCCGGGGCAC TATGCAGGCT 
GGGTTAGCAC AGCATGGGAA ACTGAGTCCA CTCTTCTTCG TTTCACAGGT TACTACTCTG 
TCGATTATCC AGACTGGCCT ATATACCTGC GTAACAGATA CACATCTCTC TTTCTCATTG 
CTAAGTCGGT TCTCCTATTA CTGTCTGTTA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Glipr1 ( XM_006514217.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006514280.1 Mus musculus GLI pathogenesis-related 1 (glioma) (Glipr1), transcript variant X1, mRNA.

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CloneID	OMu44885
Clone ID Related Accession (Same CDS sequence)	XM_006514218.4 , XM_006514217.3 , XM_006514218.3 , XM_006514217.4
Accession Version	XM_006514217.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 813bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	glioma pathogenesis-related protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000076.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006514217.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGGTCA TCCTTGCTGT GATAGTCTGG ATGGCTTCGT CTGTGTCTAG TTCTTCATTT 
ACAGCAAGCA CTTTGCCAGA TATAACAAAC GAGGACTTCA TTAAAGAATG TGTTCAAGTT 
CACAACCAGC TTCGGTCAAA AGTGAGTCCA CCAGCCCGGA ATATGCTGTA CATGTCTTGG 
GACCCAAAAC TAGCCCAAAT TGCAAAAGCA TGGACAAAAT CTTGTGAATT TAAACACAAC 
CCACAGCTGC ATTCACGGAT ACACCCAAAT TTCACCGCCC TGGGAGAGAA TATCTGGCTT 
GGCTCTCTAT CCATCTTTTC AGTATCCTCA GCCATCTCTG CCTGGTATGA AGAAATTAAG 
CACTATGACT TCAGCACTAG GAAATGTAGA CATGTCTGTG GCCATTATAC TCAGGTTGTT 
TGGGCAGACA GTTACAAACT TGGCTGTGCA GTGCAACTTT GCCCTAATGG AGCAAATTTT 
ATATGCGACT ATGGACCAGC AGGAAATTAC CCAACGTGGC CATATAAGCA AGGAGCCACG 
TGCAGTGATT GCCCAAAAGA TGACAAGTGT CTCAACAGTC TCTGCATTAA CCCACGACGA 
GACCAGGTCT CACGTATGTA TGCAAACCTT AAGCTGTTTT CCCGGGGCAC TATGCAGGCT 
GGGTTAGCAC AGCATGGGAA ACTGAGTCCA CTCTTCTTCG TTTCACAGGT TACTACTCTG 
TCGATTATCC AGACTGGCCT ATATACCTGC GTAACAGATA CACATCTCTC TTTCTCATTG 
CTAAGTCGGT TCTCCTATTA CTGTCTGTTA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006514280.1
CDS	248..1060
Translation	MQVILAVIVWMASSVSSSSFTASTLPDITNEDFIKECVQVHNQLRSKVSPPARNMLYMSWDPKLAQIAKAWTKSCEFKHNPQLHSRIHPNFTALGENIWLGSLSIFSVSSAISAWYEEIKHYDFSTRKCRHVCGHYTQVVWADSYKLGCAVQLCPNGANFICDYGPAGNYPTWPYKQGATCSDCPKDDKCLNSLCINPRRDQVSRMYANLKLFSRGTMQAGLAQHGKLSPLFFVSQVTTLSIIQTGLYTCVTDTHLSFSLLSRFSYYCLL

Target ORF information:

RefSeq Version	XM_006514217.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus GLI pathogenesis-related 1 (glioma) (Glipr1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006514217.4

ORF Insert Sequence:

ATGCAGGTCA TCCTTGCTGT GATAGTCTGG ATGGCTTCGT CTGTGTCTAG TTCTTCATTT 
ACAGCAAGCA CTTTGCCAGA TATAACAAAC GAGGACTTCA TTAAAGAATG TGTTCAAGTT 
CACAACCAGC TTCGGTCAAA AGTGAGTCCA CCAGCCCGGA ATATGCTGTA CATGTCTTGG 
GACCCAAAAC TAGCCCAAAT TGCAAAAGCA TGGACAAAAT CTTGTGAATT TAAACACAAC 
CCACAGCTGC ATTCACGGAT ACACCCAAAT TTCACCGCCC TGGGAGAGAA TATCTGGCTT 
GGCTCTCTAT CCATCTTTTC AGTATCCTCA GCCATCTCTG CCTGGTATGA AGAAATTAAG 
CACTATGACT TCAGCACTAG GAAATGTAGA CATGTCTGTG GCCATTATAC TCAGGTTGTT 
TGGGCAGACA GTTACAAACT TGGCTGTGCA GTGCAACTTT GCCCTAATGG AGCAAATTTT 
ATATGCGACT ATGGACCAGC AGGAAATTAC CCAACGTGGC CATATAAGCA AGGAGCCACG 
TGCAGTGATT GCCCAAAAGA TGACAAGTGT CTCAACAGTC TCTGCATTAA CCCACGACGA 
GACCAGGTCT CACGTATGTA TGCAAACCTT AAGCTGTTTT CCCGGGGCAC TATGCAGGCT 
GGGTTAGCAC AGCATGGGAA ACTGAGTCCA CTCTTCTTCG TTTCACAGGT TACTACTCTG 
TCGATTATCC AGACTGGCCT ATATACCTGC GTAACAGATA CACATCTCTC TTTCTCATTG 
CTAAGTCGGT TCTCCTATTA CTGTCTGTTA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

GLI pathogenesis-related 1 functions as a tumor-suppressor in lung cancer.
Molecular cancer1525(2016 Mar)
Sheng X,Bowen N,Wang Z

Combined therapeutic effects of adenoviral vector-mediated GLIPR1 gene therapy and radiotherapy in prostate and bladder cancer models.
Urologic oncology32(2)92-100(2014 Feb)
Fujita T,Satoh T,Timme TL,Hirayama T,Zhu JX,Kusaka N,Naruishi K,Yang G,Goltsov A,Wang J,Vlachaki MT,Teh BS,Brian Butler E,Thompson TC

GLIPR1 suppresses prostate cancer development through targeted oncoprotein destruction.
Cancer research71(24)7694-704(2011 Dec)
Li L,Ren C,Yang G,Fattah EA,Goltsov AA,Kim SM,Lee JS,Park S,Demayo FJ,Ittmann MM,Troncoso P,Thompson TC

Genetic variations regulate alternative splicing in the 5' untranslated regions of the mouse glioma-associated oncogene 1, Gli1.
BMC molecular biology1132(2010 Apr)
Palaniswamy R,Teglund S,Lauth M,Zaphiropoulos PG,Shimokawa T

Identification of transcripts with enriched expression in the developing and adult pancreas.
Genome biology9(6)R99(2008)
Hoffman BG,Zavaglia B,Witzsche J,Ruiz de Algara T,Beach M,Hoodless PA,Jones SJ,Marra MA,Helgason CD

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Glipr1 cDNA ORF clone, Mus musculus(house mouse)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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