Skor2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Skor2
Entrez Gene ID	664805
Full Name	SKI family transcriptional corepressor 2
Synonyms	Corl2,EG664805,Fussel18,Gm7348
General protein information	Preferred Names SKI family transcriptional corepressor 2 Names SKI family transcriptional corepressor 2 LBX1 corepressor 1-like protein functional Smad suppressor element on chromosome 18 fussel-18 homolog ladybird homeobox corepressor 1-like protein transcriptional corepressor Corl2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 18 Map Location: 18\|18 E3

mRNA and Protein(s)

mRNA	Protein	Name
XM_006526436.3	XP_006526499.1	SKI family transcriptional corepressor 2 isoform X1
NM_001109743.1	NP_001103213.1	SKI family transcriptional corepressor 2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SKOR2	XP_512119.4
Canis lupus familiaris (dog)	SKOR2	XP_547586.4
Bos taurus (cattle)	SKOR2	XP_002697863.2
Homo sapiens (human)	SKOR2	NP_001264992.1
	LOC703144	XP_001091453.2
Mus musculus (house mouse)	Skor2	NP_001103213.1
Rattus norvegicus (Norway rat)	Skor2	XP_003751855.1

Gene Ontology
Bibliography

Related articles in PubMed

Casoni F, Croci L, Bosone C, D'Ambrosio R, Badaloni A, Gaudesi D, Barili V, Sarna JR, Tessarollo L, Cremona O, Hawkes R, Warming S, Consalez GG
Development (Cambridge, England)144(20)3686-3697(2017 10)

Spatial rearrangement of Purkinje cell subsets forms the transverse and longitudinal compartmentalization in the mouse embryonic cerebellum.
Vibulyaseck S, Fujita H, Luo Y, Tran AK, Oh-Nishi A, Ono Y, Hirano S, Sugihara I
The Journal of comparative neurology525(14)2971-2990(2017 Oct)

Genome-Wide Association Mapping for Female Infertility in Inbred Mice.
Liu JL, Wang TS, Zhao M
G3 (Bethesda, Md.)6(9)2929-35(2016 09)

Characterization of Olig2 expression during cerebellar development.
Seto Y, Ishiwata S, Hoshino M
Gene expression patterns : GEP15(1)1-7(2014 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The first SNP rs29972765 is located in a gene desert on chromosome 18, about 72 kb upstream of Skor2 . The second SNP rs30415957 resides in the intron of Plce1.The remaining two SNPs (rs30768258 and rs31216810) are close to each other on chromosome 19, in the vicinity of Sorbs1. Knockdown of Sorbs1 by siRNA attenuates the induction of differentiation marker gene Prl8a2
Title: Genome-Wide Association Mapping for Female Infertility in Inbred Mice.

Corl2/Skor2 has a role in regulating cerebellar Purkinje cell differentiation in a pathway involving RORalpha
Title: The c-Ski family member and transcriptional regulator Corl2/Skor2 promotes early differentiation of cerebellar Purkinje cells.

essential function for Skor2 as a novel transcriptional regulator in Purkinje cells that acts upstream of Shh during cerebellum development
Title: Transposon mutagenesis with coat color genotyping identifies an essential role for Skor2 in sonic hedgehog signaling and cerebellum development.

Results strongly suggest that Corl2 is a specific marker for Purkinje cells in the cerebellum from their emergence until the adult stage.
Title: Identification of a novel transcriptional corepressor, Corl2, as a cerebellar Purkinje cell-selective marker.

The following Skor2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Skor2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu20348	NM_001109743.1 Latest version!	Mus musculus SKI family transcriptional corepressor 2 (Skor2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$559.30 $799.00
OMu20348	XM_006526436.3 Latest version!	Mus musculus SKI family transcriptional corepressor 2 (Skor2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$559.30 $799.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Skor2 ( NM_001109743.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001103213.1 Mus musculus SKI family transcriptional corepressor 2 (Skor2), mRNA.

Price & Availability↑

CloneID	OMu20348
Clone ID Related Accession (Same CDS sequence)	XM_006526436.3 , NM_001109743.1
Accession Version	NM_001109743.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3027bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-10
Organism	Mus musculus(house mouse)
Product	SKI family transcriptional corepressor 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB358976.1. On Oct 5, 2007 this sequence version replaced XM_001478978.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB358976.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164136, SAMN01164138 [ECO:0000348] ##Evidence-Data-END##

ATGGCTTCCA GCCCACTGCC AGGGCCCAAT GATATCCTAC TTGCATCGCC ATCGAGCGCC 
TTCCAGCCCG ACGCATTGAG CCAACCGCGG CCGGGTCACG CCAACCTTAA ACCCAACCAG 
GTGGGCCAGG TGATCCTCTA TGGCATTCCC ATCGTGTCCT TGGTGATCGA CGGGCAGGAG 
CGCCTGTGCC TGGCGCAGAT CTCCAACACT CTTCTCAAGA ACTTCAGCTA TAACGAGATC 
CACAACCGCC GAGTGGCTCT GGGCATCACG TGCGTGCAGT GCACACCTGT CCAACTGGAG 
ATCCTGCGGC GGGCCGGGGC CATGCCCATC TCTTCGCGGC GTTGTGGCAT GATCACCAAG 
CGTGAGGCCG AGCGCCTTTG TAAGTCATTC CTGGGCGAAA ATCGGCCACC CAAGCTGCCG 
GACAACTTCG CCTTCGACGT GTCGCACGAG TGTGCCTGGG GCTGCCGCGG CAGCTTCATC 
CCGGCGCGCT ACAACAGCTC TCGCGCCAAG TGCATCAAGT GTAGCTACTG CAACATGTAC 
TTCTCCCCCA ACAAGTTCAT TTTCCACTCC CACCGCACCC CAGACGCCAA GTACACACAG 
CCAGACGCGG CTAACTTCAA TTCCTGGCGC CGCCATCTCA AGCTCACAGA CAAGAGCCCT 
CAGGACGAGC TAGTCTTCGC CTGGGAGGAC GTCAAGGCCA TGTTCAACGG TGGCAGCCGC 
AAGCGCGCGC TACCTCAACC CAGCGCGCAC CCGGCCTGTC ACCCACTCAG TTCCGTCAAG 
GCTGCTGCGG TGGCGGCCGC AGCCGCAGTG GCCGGGGGCG GAGGCCTGCT GGGCCCGCAC 
CTGCTGGGGG CTCCACCCCC GCCACCGCCG CCACCACCCT TGGCTGAGCT GGCGGGCGCA 
CCTCACGCCC ATCACAAGCG GCCGCGCTTC GACGACGATG ACGATTCCCT CCAGGAAGCT 
GCCGTGGTGG CTGCAGCCAG CCTCTCGGCA GCCGCAGCCA GCCTCTCGGT GGCCGCAGCC 
ACAGGCGGCG CCGGGCCAGG CGCAGGTGGC CCCGGGGGTG GCTGCGTGGC CGGCGTGGGC 
GTGGGTGCCA GTGCGGGGGC TGGTGCAGCA GCTGGCACCA AAGGTCCACG CAGCTACCCA 
GTCATCCCAG TGCCCAGCAA GGGTTCGTTC GGGGGCGTGC TACAGAAGTT CCCGGGCTGC 
GGGGGCCTCT TCCCGCATCC TTACACCTTC CCGGCAGCGG CCGCAGCCTT CGGCTTGTGC 
CACAAGAAGG AGGACGCGGG GACAGCGGCC GAGGCCCTGG GGGGAGCGGG CGCGGGGAGC 
GCAGGTGCGG CGCCCAAGGC AGGGCTGTCG GGTCTCTTCT GGCCCGCGGG TCGCAAGGAC 
GCCTTCTACC CTCCCTTCTG CATGTTCTGG CCACCGCGGA CCCCCGGCGG GCTGCCCGTG 
CCCACCTACC TACAGCCCCC GCCGCAGCCC CCGTCTGCGC TCGGCTGCGC GCTGGGTGAT 
AGCCCGGCCC TGCTGCGTCA GGCCTTCCTG GACCTGGCCG AGCCGGGCGG TGCAGGTGGC 
AGCGCCGAGG CAGCGCCCCC TCCGGGCCAA CCTCCCCCCG TGGTGGCCAA TGGCCCTGGC 
TCCGGTCCTC CAGCTACTGG GGGCACTGGA GCACGCGACA CGCTCTTCGA GTCGCCCCCG 
GGCGGCAGCG GCGGGGACTG CAGCGCCGGG TCCACGCCAC CCGCAGAGCA AGGAGTGACG 
TCCGGGACCG GGTCTGCGTC CTCCGGAGCA GGCTCTGTGG GCACCCGAGT GCCGGCTCCC 
CATCACCCGC ACCTCCTGGA AGGGCGCAAG GCGGGCGGCG GCAGCTACCA CCATTCCAGC 
GCCTTCCGTC CGGTGGGCGG CAAGGACGAC GCAGAAAGCC TGGCCAAGCT GCACGGGGCG 
TCGGCGGGCA CACCCCACTC AGCCCCAGCG CATCACCATC ACCACCACCA TCACCCGCAC 
CATCACCACC ATCACCCTCC GCAGCCGCCG TCGCCACTGC TGCTGTTGCA GCCCCAGCCC 
GATGAGCCGG GGTCGGAGCG CCACCACCCA GCCCCGCCAC CCCCGCCACC GCCGCCCCCT 
CTGGCCCCGC AGCCGCACCA CCGAGGCCTT CTGTCCCCCG AGGGCACCAG CTGCAGCTAC 
CCCAGTGAGG ACAGCTCTGA AGACGAGGAG GACGAGGAGG AAGAGCAGGA GGTGGACGTG 
GAGGGCCACA AGCCACTCGA AGGCGAGGAA GAGGAGGACG GTCGCGATCC TGAAGATGAG 
GAGGAAGAAG ATGAGGAGAC CCGGGTCCTT CTAGGAGACT CCCTGGTTGG CGGTGGCCGG 
TTCCTCCAGG GCCGAGGGCT ATCGGAGAAG GGGAGCGGTC GGGACCGCAC GACGCCCGCC 
GTGGGTGCTT TCCCTCTAGC GCTGAACTCC TCCAGGCTGC TACAAGAGGA TGGGAAACTG 
GGGGACTCTG GAGGCTCGGA CCTGCCGGCG CCCCCGCCCC CACCCCTGGC CCCCCAGAAA 
GCAAGCAGCA GTGGGGGCAG CAGGCCAGGC AGCCCTGTCC ACCATCCATC ACTGGAGGAG 
GAGCCCTCGT ACAAAGATAA TCAGAAACCT AAGGAAAACA ACCAAGTTAT TATATCTACA 
AAGGATGACA ACTTCTCAGA TAAGAACAAG GGACATGGCT TCTTCATCAC AGATTCTGAT 
TCTTCTGGAG ACTTTTGGAG AGAAAGATCA GGTGAACATA CACAAGAAAC CAATTCACCT 
CATTCGCTCA AAAAGGATGT AGAAAACATG GGAAAAGAGG AACTTCAGAA GGTTTTGTTT 
GAGCAAATAG ATTTGCGGAG GCGGCTGGAG CAAGAATTCC AAGTGTTAAA AGGAAATACG 
TCCTTCCCAG TCTTCAATAA CTTTCAGGAT CAGATGAAAA GGGAACTGGC TTACCGAGAA 
GAGATGGTGC AACAGTTACA AATCATCCCC TATGCAGCAA GCTTGATCAG GAAAGAGAAG 
CTTGGCGCCC ATCTCAGCAA AAGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001103213.1
CDS	85..3111
Translation	MASSPLPGPNDILLASPSSAFQPDALSQPRPGHANLKPNQVGQVILYGIPIVSLVIDGQERLCLAQISNTLLKNFSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPISSRRCGMITKREAERLCKSFLGENRPPKLPDNFAFDVSHECAWGCRGSFIPARYNSSRAKCIKCSYCNMYFSPNKFIFHSHRTPDAKYTQPDAANFNSWRRHLKLTDKSPQDELVFAWEDVKAMFNGGSRKRALPQPSAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAATGGAGPGAGGPGGGCVAGVGVGASAGAGAAAGTKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFGLCHKKEDAGTAAEALGGAGAGSAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALGDSPALLRQAFLDLAEPGGAGGSAEAAPPPGQPPPVVANGPGSGPPATGGTGARDTLFESPPGGSGGDCSAGSTPPAEQGVTSGTGSASSGAGSVGTRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGTPHSAPAHHHHHHHHPHHHHHHPPQPPSPLLLLQPQPDEPGSERHHPAPPPPPPPPPLAPQPHHRGLLSPEGTSCSYPSEDSSEDEEDEEEEQEVDVEGHKPLEGEEEEDGRDPEDEEEEDEETRVLLGDSLVGGGRFLQGRGLSEKGSGRDRTTPAVGAFPLALNSSRLLQEDGKLGDSGGSDLPAPPPPPLAPQKASSSGGSRPGSPVHHPSLEEEPSYKDNQKPKENNQVIISTKDDNFSDKNKGHGFFITDSDSSGDFWRERSGEHTQETNSPHSLKKDVENMGKEELQKVLFEQIDLRRRLEQEFQVLKGNTSFPVFNNFQDQMKRELAYREEMVQQLQIIPYAASLIRKEKLGAHLSKS

Target ORF information:

RefSeq Version	NM_001109743.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus SKI family transcriptional corepressor 2 (Skor2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001109743.1

ORF Insert Sequence:

ATGGCTTCCA GCCCACTGCC AGGGCCCAAT GATATCCTAC TTGCATCGCC ATCGAGCGCC 
TTCCAGCCCG ACGCATTGAG CCAACCGCGG CCGGGTCACG CCAACCTTAA ACCCAACCAG 
GTGGGCCAGG TGATCCTCTA TGGCATTCCC ATCGTGTCCT TGGTGATCGA CGGGCAGGAG 
CGCCTGTGCC TGGCGCAGAT CTCCAACACT CTTCTCAAGA ACTTCAGCTA TAACGAGATC 
CACAACCGCC GAGTGGCTCT GGGCATCACG TGCGTGCAGT GCACACCTGT CCAACTGGAG 
ATCCTGCGGC GGGCCGGGGC CATGCCCATC TCTTCGCGGC GTTGTGGCAT GATCACCAAG 
CGTGAGGCCG AGCGCCTTTG TAAGTCATTC CTGGGCGAAA ATCGGCCACC CAAGCTGCCG 
GACAACTTCG CCTTCGACGT GTCGCACGAG TGTGCCTGGG GCTGCCGCGG CAGCTTCATC 
CCGGCGCGCT ACAACAGCTC TCGCGCCAAG TGCATCAAGT GTAGCTACTG CAACATGTAC 
TTCTCCCCCA ACAAGTTCAT TTTCCACTCC CACCGCACCC CAGACGCCAA GTACACACAG 
CCAGACGCGG CTAACTTCAA TTCCTGGCGC CGCCATCTCA AGCTCACAGA CAAGAGCCCT 
CAGGACGAGC TAGTCTTCGC CTGGGAGGAC GTCAAGGCCA TGTTCAACGG TGGCAGCCGC 
AAGCGCGCGC TACCTCAACC CAGCGCGCAC CCGGCCTGTC ACCCACTCAG TTCCGTCAAG 
GCTGCTGCGG TGGCGGCCGC AGCCGCAGTG GCCGGGGGCG GAGGCCTGCT GGGCCCGCAC 
CTGCTGGGGG CTCCACCCCC GCCACCGCCG CCACCACCCT TGGCTGAGCT GGCGGGCGCA 
CCTCACGCCC ATCACAAGCG GCCGCGCTTC GACGACGATG ACGATTCCCT CCAGGAAGCT 
GCCGTGGTGG CTGCAGCCAG CCTCTCGGCA GCCGCAGCCA GCCTCTCGGT GGCCGCAGCC 
ACAGGCGGCG CCGGGCCAGG CGCAGGTGGC CCCGGGGGTG GCTGCGTGGC CGGCGTGGGC 
GTGGGTGCCA GTGCGGGGGC TGGTGCAGCA GCTGGCACCA AAGGTCCACG CAGCTACCCA 
GTCATCCCAG TGCCCAGCAA GGGTTCGTTC GGGGGCGTGC TACAGAAGTT CCCGGGCTGC 
GGGGGCCTCT TCCCGCATCC TTACACCTTC CCGGCAGCGG CCGCAGCCTT CGGCTTGTGC 
CACAAGAAGG AGGACGCGGG GACAGCGGCC GAGGCCCTGG GGGGAGCGGG CGCGGGGAGC 
GCAGGTGCGG CGCCCAAGGC AGGGCTGTCG GGTCTCTTCT GGCCCGCGGG TCGCAAGGAC 
GCCTTCTACC CTCCCTTCTG CATGTTCTGG CCACCGCGGA CCCCCGGCGG GCTGCCCGTG 
CCCACCTACC TACAGCCCCC GCCGCAGCCC CCGTCTGCGC TCGGCTGCGC GCTGGGTGAT 
AGCCCGGCCC TGCTGCGTCA GGCCTTCCTG GACCTGGCCG AGCCGGGCGG TGCAGGTGGC 
AGCGCCGAGG CAGCGCCCCC TCCGGGCCAA CCTCCCCCCG TGGTGGCCAA TGGCCCTGGC 
TCCGGTCCTC CAGCTACTGG GGGCACTGGA GCACGCGACA CGCTCTTCGA GTCGCCCCCG 
GGCGGCAGCG GCGGGGACTG CAGCGCCGGG TCCACGCCAC CCGCAGAGCA AGGAGTGACG 
TCCGGGACCG GGTCTGCGTC CTCCGGAGCA GGCTCTGTGG GCACCCGAGT GCCGGCTCCC 
CATCACCCGC ACCTCCTGGA AGGGCGCAAG GCGGGCGGCG GCAGCTACCA CCATTCCAGC 
GCCTTCCGTC CGGTGGGCGG CAAGGACGAC GCAGAAAGCC TGGCCAAGCT GCACGGGGCG 
TCGGCGGGCA CACCCCACTC AGCCCCAGCG CATCACCATC ACCACCACCA TCACCCGCAC 
CATCACCACC ATCACCCTCC GCAGCCGCCG TCGCCACTGC TGCTGTTGCA GCCCCAGCCC 
GATGAGCCGG GGTCGGAGCG CCACCACCCA GCCCCGCCAC CCCCGCCACC GCCGCCCCCT 
CTGGCCCCGC AGCCGCACCA CCGAGGCCTT CTGTCCCCCG AGGGCACCAG CTGCAGCTAC 
CCCAGTGAGG ACAGCTCTGA AGACGAGGAG GACGAGGAGG AAGAGCAGGA GGTGGACGTG 
GAGGGCCACA AGCCACTCGA AGGCGAGGAA GAGGAGGACG GTCGCGATCC TGAAGATGAG 
GAGGAAGAAG ATGAGGAGAC CCGGGTCCTT CTAGGAGACT CCCTGGTTGG CGGTGGCCGG 
TTCCTCCAGG GCCGAGGGCT ATCGGAGAAG GGGAGCGGTC GGGACCGCAC GACGCCCGCC 
GTGGGTGCTT TCCCTCTAGC GCTGAACTCC TCCAGGCTGC TACAAGAGGA TGGGAAACTG 
GGGGACTCTG GAGGCTCGGA CCTGCCGGCG CCCCCGCCCC CACCCCTGGC CCCCCAGAAA 
GCAAGCAGCA GTGGGGGCAG CAGGCCAGGC AGCCCTGTCC ACCATCCATC ACTGGAGGAG 
GAGCCCTCGT ACAAAGATAA TCAGAAACCT AAGGAAAACA ACCAAGTTAT TATATCTACA 
AAGGATGACA ACTTCTCAGA TAAGAACAAG GGACATGGCT TCTTCATCAC AGATTCTGAT 
TCTTCTGGAG ACTTTTGGAG AGAAAGATCA GGTGAACATA CACAAGAAAC CAATTCACCT 
CATTCGCTCA AAAAGGATGT AGAAAACATG GGAAAAGAGG AACTTCAGAA GGTTTTGTTT 
GAGCAAATAG ATTTGCGGAG GCGGCTGGAG CAAGAATTCC AAGTGTTAAA AGGAAATACG 
TCCTTCCCAG TCTTCAATAA CTTTCAGGAT CAGATGAAAA GGGAACTGGC TTACCGAGAA 
GAGATGGTGC AACAGTTACA AATCATCCCC TATGCAGCAA GCTTGATCAG GAAAGAGAAG 
CTTGGCGCCC ATCTCAGCAA AAGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Skor2 ( XM_006526436.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006526499.1 Mus musculus SKI family transcriptional corepressor 2 (Skor2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu20348
Clone ID Related Accession (Same CDS sequence)	XM_006526436.3 , NM_001109743.1
Accession Version	XM_006526436.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3027bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	SKI family transcriptional corepressor 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006526436.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTTCCA GCCCACTGCC AGGGCCCAAT GATATCCTAC TTGCATCGCC ATCGAGCGCC 
TTCCAGCCCG ACGCATTGAG CCAACCGCGG CCGGGTCACG CCAACCTTAA ACCCAACCAG 
GTGGGCCAGG TGATCCTCTA TGGCATTCCC ATCGTGTCCT TGGTGATCGA CGGGCAGGAG 
CGCCTGTGCC TGGCGCAGAT CTCCAACACT CTTCTCAAGA ACTTCAGCTA TAACGAGATC 
CACAACCGCC GAGTGGCTCT GGGCATCACG TGCGTGCAGT GCACACCTGT CCAACTGGAG 
ATCCTGCGGC GGGCCGGGGC CATGCCCATC TCTTCGCGGC GTTGTGGCAT GATCACCAAG 
CGTGAGGCCG AGCGCCTTTG TAAGTCATTC CTGGGCGAAA ATCGGCCACC CAAGCTGCCG 
GACAACTTCG CCTTCGACGT GTCGCACGAG TGTGCCTGGG GCTGCCGCGG CAGCTTCATC 
CCGGCGCGCT ACAACAGCTC TCGCGCCAAG TGCATCAAGT GTAGCTACTG CAACATGTAC 
TTCTCCCCCA ACAAGTTCAT TTTCCACTCC CACCGCACCC CAGACGCCAA GTACACACAG 
CCAGACGCGG CTAACTTCAA TTCCTGGCGC CGCCATCTCA AGCTCACAGA CAAGAGCCCT 
CAGGACGAGC TAGTCTTCGC CTGGGAGGAC GTCAAGGCCA TGTTCAACGG TGGCAGCCGC 
AAGCGCGCGC TACCTCAACC CAGCGCGCAC CCGGCCTGTC ACCCACTCAG TTCCGTCAAG 
GCTGCTGCGG TGGCGGCCGC AGCCGCAGTG GCCGGGGGCG GAGGCCTGCT GGGCCCGCAC 
CTGCTGGGGG CTCCACCCCC GCCACCGCCG CCACCACCCT TGGCTGAGCT GGCGGGCGCA 
CCTCACGCCC ATCACAAGCG GCCGCGCTTC GACGACGATG ACGATTCCCT CCAGGAAGCT 
GCCGTGGTGG CTGCAGCCAG CCTCTCGGCA GCCGCAGCCA GCCTCTCGGT GGCCGCAGCC 
ACAGGCGGCG CCGGGCCAGG CGCAGGTGGC CCCGGGGGTG GCTGCGTGGC CGGCGTGGGC 
GTGGGTGCCA GTGCGGGGGC TGGTGCAGCA GCTGGCACCA AAGGTCCACG CAGCTACCCA 
GTCATCCCAG TGCCCAGCAA GGGTTCGTTC GGGGGCGTGC TACAGAAGTT CCCGGGCTGC 
GGGGGCCTCT TCCCGCATCC TTACACCTTC CCGGCAGCGG CCGCAGCCTT CGGCTTGTGC 
CACAAGAAGG AGGACGCGGG GACAGCGGCC GAGGCCCTGG GGGGAGCGGG CGCGGGGAGC 
GCAGGTGCGG CGCCCAAGGC AGGGCTGTCG GGTCTCTTCT GGCCCGCGGG TCGCAAGGAC 
GCCTTCTACC CTCCCTTCTG CATGTTCTGG CCACCGCGGA CCCCCGGCGG GCTGCCCGTG 
CCCACCTACC TACAGCCCCC GCCGCAGCCC CCGTCTGCGC TCGGCTGCGC GCTGGGTGAT 
AGCCCGGCCC TGCTGCGTCA GGCCTTCCTG GACCTGGCCG AGCCGGGCGG TGCAGGTGGC 
AGCGCCGAGG CAGCGCCCCC TCCGGGCCAA CCTCCCCCCG TGGTGGCCAA TGGCCCTGGC 
TCCGGTCCTC CAGCTACTGG GGGCACTGGA GCACGCGACA CGCTCTTCGA GTCGCCCCCG 
GGCGGCAGCG GCGGGGACTG CAGCGCCGGG TCCACGCCAC CCGCAGAGCA AGGAGTGACG 
TCCGGGACCG GGTCTGCGTC CTCCGGAGCA GGCTCTGTGG GCACCCGAGT GCCGGCTCCC 
CATCACCCGC ACCTCCTGGA AGGGCGCAAG GCGGGCGGCG GCAGCTACCA CCATTCCAGC 
GCCTTCCGTC CGGTGGGCGG CAAGGACGAC GCAGAAAGCC TGGCCAAGCT GCACGGGGCG 
TCGGCGGGCA CACCCCACTC AGCCCCAGCG CATCACCATC ACCACCACCA TCACCCGCAC 
CATCACCACC ATCACCCTCC GCAGCCGCCG TCGCCACTGC TGCTGTTGCA GCCCCAGCCC 
GATGAGCCGG GGTCGGAGCG CCACCACCCA GCCCCGCCAC CCCCGCCACC GCCGCCCCCT 
CTGGCCCCGC AGCCGCACCA CCGAGGCCTT CTGTCCCCCG AGGGCACCAG CTGCAGCTAC 
CCCAGTGAGG ACAGCTCTGA AGACGAGGAG GACGAGGAGG AAGAGCAGGA GGTGGACGTG 
GAGGGCCACA AGCCACTCGA AGGCGAGGAA GAGGAGGACG GTCGCGATCC TGAAGATGAG 
GAGGAAGAAG ATGAGGAGAC CCGGGTCCTT CTAGGAGACT CCCTGGTTGG CGGTGGCCGG 
TTCCTCCAGG GCCGAGGGCT ATCGGAGAAG GGGAGCGGTC GGGACCGCAC GACGCCCGCC 
GTGGGTGCTT TCCCTCTAGC GCTGAACTCC TCCAGGCTGC TACAAGAGGA TGGGAAACTG 
GGGGACTCTG GAGGCTCGGA CCTGCCGGCG CCCCCGCCCC CACCCCTGGC CCCCCAGAAA 
GCAAGCAGCA GTGGGGGCAG CAGGCCAGGC AGCCCTGTCC ACCATCCATC ACTGGAGGAG 
GAGCCCTCGT ACAAAGATAA TCAGAAACCT AAGGAAAACA ACCAAGTTAT TATATCTACA 
AAGGATGACA ACTTCTCAGA TAAGAACAAG GGACATGGCT TCTTCATCAC AGATTCTGAT 
TCTTCTGGAG ACTTTTGGAG AGAAAGATCA GGTGAACATA CACAAGAAAC CAATTCACCT 
CATTCGCTCA AAAAGGATGT AGAAAACATG GGAAAAGAGG AACTTCAGAA GGTTTTGTTT 
GAGCAAATAG ATTTGCGGAG GCGGCTGGAG CAAGAATTCC AAGTGTTAAA AGGAAATACG 
TCCTTCCCAG TCTTCAATAA CTTTCAGGAT CAGATGAAAA GGGAACTGGC TTACCGAGAA 
GAGATGGTGC AACAGTTACA AATCATCCCC TATGCAGCAA GCTTGATCAG GAAAGAGAAG 
CTTGGCGCCC ATCTCAGCAA AAGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006526499.1
CDS	370..3396
Translation	MASSPLPGPNDILLASPSSAFQPDALSQPRPGHANLKPNQVGQVILYGIPIVSLVIDGQERLCLAQISNTLLKNFSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPISSRRCGMITKREAERLCKSFLGENRPPKLPDNFAFDVSHECAWGCRGSFIPARYNSSRAKCIKCSYCNMYFSPNKFIFHSHRTPDAKYTQPDAANFNSWRRHLKLTDKSPQDELVFAWEDVKAMFNGGSRKRALPQPSAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAATGGAGPGAGGPGGGCVAGVGVGASAGAGAAAGTKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFGLCHKKEDAGTAAEALGGAGAGSAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALGDSPALLRQAFLDLAEPGGAGGSAEAAPPPGQPPPVVANGPGSGPPATGGTGARDTLFESPPGGSGGDCSAGSTPPAEQGVTSGTGSASSGAGSVGTRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGTPHSAPAHHHHHHHHPHHHHHHPPQPPSPLLLLQPQPDEPGSERHHPAPPPPPPPPPLAPQPHHRGLLSPEGTSCSYPSEDSSEDEEDEEEEQEVDVEGHKPLEGEEEEDGRDPEDEEEEDEETRVLLGDSLVGGGRFLQGRGLSEKGSGRDRTTPAVGAFPLALNSSRLLQEDGKLGDSGGSDLPAPPPPPLAPQKASSSGGSRPGSPVHHPSLEEEPSYKDNQKPKENNQVIISTKDDNFSDKNKGHGFFITDSDSSGDFWRERSGEHTQETNSPHSLKKDVENMGKEELQKVLFEQIDLRRRLEQEFQVLKGNTSFPVFNNFQDQMKRELAYREEMVQQLQIIPYAASLIRKEKLGAHLSKS

Target ORF information:

RefSeq Version	XM_006526436.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus SKI family transcriptional corepressor 2 (Skor2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006526436.3

ORF Insert Sequence:

ATGGCTTCCA GCCCACTGCC AGGGCCCAAT GATATCCTAC TTGCATCGCC ATCGAGCGCC 
TTCCAGCCCG ACGCATTGAG CCAACCGCGG CCGGGTCACG CCAACCTTAA ACCCAACCAG 
GTGGGCCAGG TGATCCTCTA TGGCATTCCC ATCGTGTCCT TGGTGATCGA CGGGCAGGAG 
CGCCTGTGCC TGGCGCAGAT CTCCAACACT CTTCTCAAGA ACTTCAGCTA TAACGAGATC 
CACAACCGCC GAGTGGCTCT GGGCATCACG TGCGTGCAGT GCACACCTGT CCAACTGGAG 
ATCCTGCGGC GGGCCGGGGC CATGCCCATC TCTTCGCGGC GTTGTGGCAT GATCACCAAG 
CGTGAGGCCG AGCGCCTTTG TAAGTCATTC CTGGGCGAAA ATCGGCCACC CAAGCTGCCG 
GACAACTTCG CCTTCGACGT GTCGCACGAG TGTGCCTGGG GCTGCCGCGG CAGCTTCATC 
CCGGCGCGCT ACAACAGCTC TCGCGCCAAG TGCATCAAGT GTAGCTACTG CAACATGTAC 
TTCTCCCCCA ACAAGTTCAT TTTCCACTCC CACCGCACCC CAGACGCCAA GTACACACAG 
CCAGACGCGG CTAACTTCAA TTCCTGGCGC CGCCATCTCA AGCTCACAGA CAAGAGCCCT 
CAGGACGAGC TAGTCTTCGC CTGGGAGGAC GTCAAGGCCA TGTTCAACGG TGGCAGCCGC 
AAGCGCGCGC TACCTCAACC CAGCGCGCAC CCGGCCTGTC ACCCACTCAG TTCCGTCAAG 
GCTGCTGCGG TGGCGGCCGC AGCCGCAGTG GCCGGGGGCG GAGGCCTGCT GGGCCCGCAC 
CTGCTGGGGG CTCCACCCCC GCCACCGCCG CCACCACCCT TGGCTGAGCT GGCGGGCGCA 
CCTCACGCCC ATCACAAGCG GCCGCGCTTC GACGACGATG ACGATTCCCT CCAGGAAGCT 
GCCGTGGTGG CTGCAGCCAG CCTCTCGGCA GCCGCAGCCA GCCTCTCGGT GGCCGCAGCC 
ACAGGCGGCG CCGGGCCAGG CGCAGGTGGC CCCGGGGGTG GCTGCGTGGC CGGCGTGGGC 
GTGGGTGCCA GTGCGGGGGC TGGTGCAGCA GCTGGCACCA AAGGTCCACG CAGCTACCCA 
GTCATCCCAG TGCCCAGCAA GGGTTCGTTC GGGGGCGTGC TACAGAAGTT CCCGGGCTGC 
GGGGGCCTCT TCCCGCATCC TTACACCTTC CCGGCAGCGG CCGCAGCCTT CGGCTTGTGC 
CACAAGAAGG AGGACGCGGG GACAGCGGCC GAGGCCCTGG GGGGAGCGGG CGCGGGGAGC 
GCAGGTGCGG CGCCCAAGGC AGGGCTGTCG GGTCTCTTCT GGCCCGCGGG TCGCAAGGAC 
GCCTTCTACC CTCCCTTCTG CATGTTCTGG CCACCGCGGA CCCCCGGCGG GCTGCCCGTG 
CCCACCTACC TACAGCCCCC GCCGCAGCCC CCGTCTGCGC TCGGCTGCGC GCTGGGTGAT 
AGCCCGGCCC TGCTGCGTCA GGCCTTCCTG GACCTGGCCG AGCCGGGCGG TGCAGGTGGC 
AGCGCCGAGG CAGCGCCCCC TCCGGGCCAA CCTCCCCCCG TGGTGGCCAA TGGCCCTGGC 
TCCGGTCCTC CAGCTACTGG GGGCACTGGA GCACGCGACA CGCTCTTCGA GTCGCCCCCG 
GGCGGCAGCG GCGGGGACTG CAGCGCCGGG TCCACGCCAC CCGCAGAGCA AGGAGTGACG 
TCCGGGACCG GGTCTGCGTC CTCCGGAGCA GGCTCTGTGG GCACCCGAGT GCCGGCTCCC 
CATCACCCGC ACCTCCTGGA AGGGCGCAAG GCGGGCGGCG GCAGCTACCA CCATTCCAGC 
GCCTTCCGTC CGGTGGGCGG CAAGGACGAC GCAGAAAGCC TGGCCAAGCT GCACGGGGCG 
TCGGCGGGCA CACCCCACTC AGCCCCAGCG CATCACCATC ACCACCACCA TCACCCGCAC 
CATCACCACC ATCACCCTCC GCAGCCGCCG TCGCCACTGC TGCTGTTGCA GCCCCAGCCC 
GATGAGCCGG GGTCGGAGCG CCACCACCCA GCCCCGCCAC CCCCGCCACC GCCGCCCCCT 
CTGGCCCCGC AGCCGCACCA CCGAGGCCTT CTGTCCCCCG AGGGCACCAG CTGCAGCTAC 
CCCAGTGAGG ACAGCTCTGA AGACGAGGAG GACGAGGAGG AAGAGCAGGA GGTGGACGTG 
GAGGGCCACA AGCCACTCGA AGGCGAGGAA GAGGAGGACG GTCGCGATCC TGAAGATGAG 
GAGGAAGAAG ATGAGGAGAC CCGGGTCCTT CTAGGAGACT CCCTGGTTGG CGGTGGCCGG 
TTCCTCCAGG GCCGAGGGCT ATCGGAGAAG GGGAGCGGTC GGGACCGCAC GACGCCCGCC 
GTGGGTGCTT TCCCTCTAGC GCTGAACTCC TCCAGGCTGC TACAAGAGGA TGGGAAACTG 
GGGGACTCTG GAGGCTCGGA CCTGCCGGCG CCCCCGCCCC CACCCCTGGC CCCCCAGAAA 
GCAAGCAGCA GTGGGGGCAG CAGGCCAGGC AGCCCTGTCC ACCATCCATC ACTGGAGGAG 
GAGCCCTCGT ACAAAGATAA TCAGAAACCT AAGGAAAACA ACCAAGTTAT TATATCTACA 
AAGGATGACA ACTTCTCAGA TAAGAACAAG GGACATGGCT TCTTCATCAC AGATTCTGAT 
TCTTCTGGAG ACTTTTGGAG AGAAAGATCA GGTGAACATA CACAAGAAAC CAATTCACCT 
CATTCGCTCA AAAAGGATGT AGAAAACATG GGAAAAGAGG AACTTCAGAA GGTTTTGTTT 
GAGCAAATAG ATTTGCGGAG GCGGCTGGAG CAAGAATTCC AAGTGTTAAA AGGAAATACG 
TCCTTCCCAG TCTTCAATAA CTTTCAGGAT CAGATGAAAA GGGAACTGGC TTACCGAGAA 
GAGATGGTGC AACAGTTACA AATCATCCCC TATGCAGCAA GCTTGATCAG GAAAGAGAAG 
CTTGGCGCCC ATCTCAGCAA AAGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Development (Cambridge, England)144(20)3686-3697(2017 10)
Casoni F,Croci L,Bosone C,D'Ambrosio R,Badaloni A,Gaudesi D,Barili V,Sarna JR,Tessarollo L,Cremona O,Hawkes R,Warming S,Consalez GG

Spatial rearrangement of Purkinje cell subsets forms the transverse and longitudinal compartmentalization in the mouse embryonic cerebellum.
The Journal of comparative neurology525(14)2971-2990(2017 Oct)
Vibulyaseck S,Fujita H,Luo Y,Tran AK,Oh-Nishi A,Ono Y,Hirano S,Sugihara I

Genome-Wide Association Mapping for Female Infertility in Inbred Mice.
G3 (Bethesda, Md.)6(9)2929-35(2016 09)
Liu JL,Wang TS,Zhao M

Characterization of Olig2 expression during cerebellar development.
Gene expression patterns : GEP15(1)1-7(2014 May)
Seto Y,Ishiwata S,Hoshino M