Usp17le cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Usp17le
Entrez Gene ID	625530
Full Name	ubiquitin specific peptidase 17-like E
Synonyms	DUB-3,Dub3,Dub6,EG625530,Gm6596,USP17,USP17-E,Usp17l2
General protein information	Preferred Names ubiquitin specific peptidase 17-like E Names ubiquitin carboxyl-terminal hydrolase 17-like protein E deubiquitinating enzyme 17-like protein 2 deubiquitinating enzyme 3 deubiquitinating enzyme 6 deubiquitinating protein 3 deubiquitinating protein 6 ubiquitin carboxyl-terminal hydrolase 17 ubiquitin carboxyl-terminal hydrolase 17-like protein 2 ubiquitin thioesterase 17-like protein 2 ubiquitin thiolesterase 17-like protein 2 ubiquitin-specific-processing protease 17-like protein 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 7 Map Location: 7 E3\|7 55.69 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_011241878.2	XP_011240180.1	ubiquitin carboxyl-terminal hydrolase 17-like protein E isoform X2
XM_017322434.1	XP_017177923.1	ubiquitin carboxyl-terminal hydrolase 17-like protein E isoform X1
NM_001256973.1	NP_001243902.1	ubiquitin carboxyl-terminal hydrolase 17-like protein E

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LOC471141	XP_001139436.1
Canis lupus familiaris (dog)	LOC611374	XP_854129.2
Rattus norvegicus (Norway rat)	LOC689730	XP_001071809.3
Rattus norvegicus (Norway rat)	Usp17l5	XP_219062.4
Canis lupus familiaris (dog)	LOC482940	XP_540055.3
Canis lupus familiaris (dog)	USP17L17	XP_003640328.1
Canis lupus familiaris (dog)	LOC100855657	XP_003640329.1
Canis lupus familiaris (dog)	LOC611292	XP_854031.1
Mus musculus (house mouse)	Usp17ld	NP_001001559.2
Mus musculus (house mouse)	Usp17lc	NP_034219.3
Mus musculus (house mouse)	Usp17lb	NP_958811.2
Canis lupus familiaris (dog)	LOC611251	XP_005630114.1
Canis lupus familiaris (dog)	LOC609437	XP_851787.2
Canis lupus familiaris (dog)	LOC100686197	XP_003435458.1
Canis lupus familiaris (dog)	LOC100856115	XP_003639838.1
Canis lupus familiaris (dog)	LOC609310	XP_851647.3
Mus musculus (house mouse)	Usp17le	NP_001243902.1
	USP17L10	XP_001082678.1
Canis lupus familiaris (dog)	LOC609268	XP_851591.2
Canis lupus familiaris (dog)	LOC100686685	XP_003435418.1
Canis lupus familiaris (dog)	LOC100855682	XP_003640330.1
Bos taurus (cattle)	USP17L5	XP_002707829.1
Mus musculus (house mouse)	Usp17la	NP_031913.1

Gene Ontology
Bibliography

Related articles in PubMed

CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1.
Liu T, Yu J, Deng M, Yin Y, Zhang H, Luo K, Qin B, Li Y, Wu C, Ren T, Han Y, Yin P, Kim J, Lee S, Lin J, Zhang L, Zhang J, Nowsheen S, Wang L, Boughey J, Goetz MP, Yuan J, Lou Z
Nature communications813923(2017 Jan)

Cell cycle-dependent expression of Dub3, Nanog and the p160 family of nuclear receptor coactivators (NCoAs) in mouse embryonic stem cells.
van der Laan S, Golfetto E, Vanacker JM, Maiorano D
PloS one9(4)e93663(2014)

High Dub3 expression in mouse ESCs couples the G1/S checkpoint to pluripotency.
van der Laan S, Tsanov N, Crozet C, Maiorano D
Molecular cell52(3)366-79(2013 Nov)

Polyclonal and monoclonal antibodies specific for USP17, a proapoptotic deubiquitinating enzyme.
Ramakrishna S, Suresh B, Kang IC, Baek KH
Hybridoma (2005)29(4)311-9(2010 Aug)

The DUB/USP17 deubiquitinating enzymes: a gene family within a tandemly repeated sequence, is also embedded within the copy number variable beta-defensin cluster.
Burrows JF, Scott CJ, Johnston JA
BMC genomics11250(2010 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Using a reporter assay, we show that NCoA1 potentiates Esrrb-mediated transcription of Dub3 and we present evidence of protein interaction between the SRC1 splice variant NCoA1 and Esrrb
Title: Cell cycle-dependent expression of Dub3, Nanog and the p160 family of nuclear receptor coactivators (NCoAs) in mouse embryonic stem cells.

We show that Dub3 expression is strongly downregulated during neural conversion and precedes Cdc25A destabilization, while forced Dub3 expression in ESCs becomes lethal upon differentiation
Title: High Dub3 expression in mouse ESCs couples the G1/S checkpoint to pluripotency.

The following Usp17le gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Usp17le cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu13578	NM_001256973.1 Latest version!	Mus musculus ubiquitin specific peptidase 17-like E (Usp17le), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OMu75451	XM_011241878.2 Latest version!	Mus musculus ubiquitin specific peptidase 17-like E (Usp17le), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$307.30 $439.00
OMu82171	XM_017322434.1 Latest version!	Mus musculus ubiquitin specific peptidase 17-like E (Usp17le), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Usp17le ( NM_001256973.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001243902.1 Mus musculus ubiquitin specific peptidase 17-like E (Usp17le), mRNA.

Price & Availability↑

CloneID	OMu13578
Clone ID Related Accession (Same CDS sequence)	NM_001256973.1
Accession Version	NM_001256973.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1623bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-21
Organism	Mus musculus(house mouse)
Product	ubiquitin carboxyl-terminal hydrolase 17-like protein E
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC110621.6. On or before Mar 10, 2012 this sequence version replaced XM_001476444.2, XM_890107.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BY748110.1, BY749173.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849383, SAMN01164134 [ECO:0000350] ##Evidence-Data-END##

ATGGTGGTTT CTCTTTCCTT CCCAGAAGAG ACTGGAGGGG AAAATCTTCC TTCTGCTCCC 
TTAGAAGACT CCAGCAAGTT CTTTGAAGAG GTCTTTGGAG ACATGGTGGT TGCTCTTTCC 
TTCCCAGAAG CAGATCCAGC ACTATCATCT CCTGATGCCC CAGAGCTGCA TCAGGATGAA 
GCTCAGGTGG TGGAGGAGCT AACTACCAAT GGAAAGCACA GTCTGAGTTG GGAGAGTCCC 
CAAGGACCAG GATGCGGGCT CCAGAACACA GGCAACAGCT GCTACCTGAA CGCAGCCCTG 
CAGTGCTTGA CACACACACC ACCTCTAGCT GACTACATGC TGTCCCAGGA GCACAGTCAA 
ACCTGTTGTT CCCCAGAAGG CTGTAAGATG TGTGCTATGG AAGCCCATGT GACCCAGAGT 
CTCCTGCACT CTCACTCGGG GGATGTCATG AAGCCCTCCC AGATTTTGAC CTCTGCCTTC 
CACAAGCACC AGCAGGAAGA TGCCCATGAG TTTCTCATGT TCACCTTGGA AACAATGCAT 
GAATCCTGCC TTCAAGTGCA CAGACAATCA GATCCCACCC CTCAGGATAC GTCACCCATT 
CATGACATAT TTGGAGGCTG GTGGAGGTCT CAGATCAAGT GTCTCCATTG CCAGGGCACC 
TCACATACCT TCGATCCCTT CCTGGATGTC CCCCTGGATA TCAGCTCAGC TCAGAGTGTA 
AATCAAGCCT TGTGGGATAC AGGGAAGTCA GAAGAGCTAC TTGGAGAGAA TGCCTACTAC 
TGTGGTAGGT GTAGACAGAA GATGCCAGCT TCTAAGACCC TGCATGTTCA TATTGCTCCA 
AAGGTACTCC TGCTAGTGTT AAAGCGCTTC TCAGCCTTCA CGGGTAACAA GTTAGACAGA 
AAAGTAAGCT ACCCGGAGTT CCTTGACCTG AAGCCATACC TGTCTGAGCC TACTGGAGGA 
CCTTTGCCTT ATGCCCTCTA TGCCGTCCTG GTCCATGATG GTGCGACTTC TAACAGTGGA 
CATTACTTCT GTTGTGTCAA AGCTGGTCAT GGGAAGTGGT ACAAGATGGA TGATACTAAG 
GTCACCAGGT GTGATGTGAC TTCTGTCCTG AATGAGAATG CCTATGTGCT CTTCTATGTG 
CAGCAGACCG ACCTCAAACA GGTCAGTATT GACATGCCAG AGGGCAGAGT ACATGAGGTT 
CTTGACCCTA AATACCAGCT GAAGAAATCC CGGAGAAAAA AGCGTAAGAA GCAATGCCAT 
TGCACAGATG ATGCCGGAGA GGCATGCGAA AACAGGGAGA AGAGAGCAAA GAAAGAAACC 
TCCTTAGGGG AGGGGAAAGT GCCTCAGGAA GTGAACCACG AGAAAGCTGG GCAGAAACAT 
GGGAATACCA AACTCGTGCC TCAGGAACAG AACCACCAGA GAGCTGGGCA GAACCTCAGG 
AATACTGAAG TTGAACTTGA TCTGCCTGTT GATGCAATTG TGATTCACCA GCCCAGATCC 
ACAGCAAACT GGGGCACGGA TGCTCCAGAC AAAGAGAATC AACCCTGGCA CAATGGTGAC 
AGGCTCCTCA CCTCTCAGGG CCTCATGAGC CCTGGGCAGC TCTGTAGTCA GGGTGGGAGA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001243902.1
CDS	1..1623
Translation	MVVSLSFPEETGGENLPSAPLEDSSKFFEEVFGDMVVALSFPEADPALSSPDAPELHQDEAQVVEELTTNGKHSLSWESPQGPGCGLQNTGNSCYLNAALQCLTHTPPLADYMLSQEHSQTCCSPEGCKMCAMEAHVTQSLLHSHSGDVMKPSQILTSAFHKHQQEDAHEFLMFTLETMHESCLQVHRQSDPTPQDTSPIHDIFGGWWRSQIKCLHCQGTSHTFDPFLDVPLDISSAQSVNQALWDTGKSEELLGENAYYCGRCRQKMPASKTLHVHIAPKVLLLVLKRFSAFTGNKLDRKVSYPEFLDLKPYLSEPTGGPLPYALYAVLVHDGATSNSGHYFCCVKAGHGKWYKMDDTKVTRCDVTSVLNENAYVLFYVQQTDLKQVSIDMPEGRVHEVLDPKYQLKKSRRKKRKKQCHCTDDAGEACENREKRAKKETSLGEGKVPQEVNHEKAGQKHGNTKLVPQEQNHQRAGQNLRNTEVELDLPVDAIVIHQPRSTANWGTDAPDKENQPWHNGDRLLTSQGLMSPGQLCSQGGR

Target ORF information:

RefSeq Version	NM_001256973.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus ubiquitin specific peptidase 17-like E (Usp17le), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001256973.1

ORF Insert Sequence:

ATGGTGGTTT CTCTTTCCTT CCCAGAAGAG ACTGGAGGGG AAAATCTTCC TTCTGCTCCC 
TTAGAAGACT CCAGCAAGTT CTTTGAAGAG GTCTTTGGAG ACATGGTGGT TGCTCTTTCC 
TTCCCAGAAG CAGATCCAGC ACTATCATCT CCTGATGCCC CAGAGCTGCA TCAGGATGAA 
GCTCAGGTGG TGGAGGAGCT AACTACCAAT GGAAAGCACA GTCTGAGTTG GGAGAGTCCC 
CAAGGACCAG GATGCGGGCT CCAGAACACA GGCAACAGCT GCTACCTGAA CGCAGCCCTG 
CAGTGCTTGA CACACACACC ACCTCTAGCT GACTACATGC TGTCCCAGGA GCACAGTCAA 
ACCTGTTGTT CCCCAGAAGG CTGTAAGATG TGTGCTATGG AAGCCCATGT GACCCAGAGT 
CTCCTGCACT CTCACTCGGG GGATGTCATG AAGCCCTCCC AGATTTTGAC CTCTGCCTTC 
CACAAGCACC AGCAGGAAGA TGCCCATGAG TTTCTCATGT TCACCTTGGA AACAATGCAT 
GAATCCTGCC TTCAAGTGCA CAGACAATCA GATCCCACCC CTCAGGATAC GTCACCCATT 
CATGACATAT TTGGAGGCTG GTGGAGGTCT CAGATCAAGT GTCTCCATTG CCAGGGCACC 
TCACATACCT TCGATCCCTT CCTGGATGTC CCCCTGGATA TCAGCTCAGC TCAGAGTGTA 
AATCAAGCCT TGTGGGATAC AGGGAAGTCA GAAGAGCTAC TTGGAGAGAA TGCCTACTAC 
TGTGGTAGGT GTAGACAGAA GATGCCAGCT TCTAAGACCC TGCATGTTCA TATTGCTCCA 
AAGGTACTCC TGCTAGTGTT AAAGCGCTTC TCAGCCTTCA CGGGTAACAA GTTAGACAGA 
AAAGTAAGCT ACCCGGAGTT CCTTGACCTG AAGCCATACC TGTCTGAGCC TACTGGAGGA 
CCTTTGCCTT ATGCCCTCTA TGCCGTCCTG GTCCATGATG GTGCGACTTC TAACAGTGGA 
CATTACTTCT GTTGTGTCAA AGCTGGTCAT GGGAAGTGGT ACAAGATGGA TGATACTAAG 
GTCACCAGGT GTGATGTGAC TTCTGTCCTG AATGAGAATG CCTATGTGCT CTTCTATGTG 
CAGCAGACCG ACCTCAAACA GGTCAGTATT GACATGCCAG AGGGCAGAGT ACATGAGGTT 
CTTGACCCTA AATACCAGCT GAAGAAATCC CGGAGAAAAA AGCGTAAGAA GCAATGCCAT 
TGCACAGATG ATGCCGGAGA GGCATGCGAA AACAGGGAGA AGAGAGCAAA GAAAGAAACC 
TCCTTAGGGG AGGGGAAAGT GCCTCAGGAA GTGAACCACG AGAAAGCTGG GCAGAAACAT 
GGGAATACCA AACTCGTGCC TCAGGAACAG AACCACCAGA GAGCTGGGCA GAACCTCAGG 
AATACTGAAG TTGAACTTGA TCTGCCTGTT GATGCAATTG TGATTCACCA GCCCAGATCC 
ACAGCAAACT GGGGCACGGA TGCTCCAGAC AAAGAGAATC AACCCTGGCA CAATGGTGAC 
AGGCTCCTCA CCTCTCAGGG CCTCATGAGC CCTGGGCAGC TCTGTAGTCA GGGTGGGAGA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Usp17le ( XM_011241878.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011240180.1 Mus musculus ubiquitin specific peptidase 17-like E (Usp17le), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu75451
Clone ID Related Accession (Same CDS sequence)	XM_011241878.2
Accession Version	XM_011241878.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1521bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	ubiquitin carboxyl-terminal hydrolase 17-like protein E isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011241878.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGGTTT CTCTTTCCTT CCCAGAAGCA GATCCAGCAC TATCATCTCC TGATGCCCCA 
GAGCTGCATC AGGATGAAGC TCAGGTGGTG GAGGAGCTAA CTACCAATGG AAAGCACAGT 
CTGAGTTGGG AGAGTCCCCA AGGACCAGGA TGCGGGCTCC AGAACACAGG CAACAGCTGC 
TACCTGAACG CAGCCCTGCA GTGCTTGACA CACACACCAC CTCTAGCTGA CTACATGCTG 
TCCCAGGAGC ACAGTCAAAC CTGTTGTTCC CCAGAAGGCT GTAAGATGTG TGCTATGGAA 
GCCCATGTGA CCCAGAGTCT CCTGCACTCT CACTCGGGGG ATGTCATGAA GCCCTCCCAG 
ATTTTGACCT CTGCCTTCCA CAAGCACCAG CAGGAAGATG CCCATGAGTT TCTCATGTTC 
ACCTTGGAAA CAATGCATGA ATCCTGCCTT CAAGTGCACA GACAATCAGA TCCCACCCCT 
CAGGATACGT CACCCATTCA TGACATATTT GGAGGCTGGT GGAGGTCTCA GATCAAGTGT 
CTCCATTGCC AGGGCACCTC ACATACCTTC GATCCCTTCC TGGATGTCCC CCTGGATATC 
AGCTCAGCTC AGAGTGTAAA TCAAGCCTTG TGGGATACAG GGAAGTCAGA AGAGCTACTT 
GGAGAGAATG CCTACTACTG TGGTAGGTGT AGACAGAAGA TGCCAGCTTC TAAGACCCTG 
CATGTTCATA TTGCTCCAAA GGTACTCCTG CTAGTGTTAA AGCGCTTCTC AGCCTTCACG 
GGTAACAAGT TAGACAGAAA AGTAAGCTAC CCGGAGTTCC TTGACCTGAA GCCATACCTG 
TCTGAGCCTA CTGGAGGACC TTTGCCTTAT GCCCTCTATG CCGTCCTGGT CCATGATGGT 
GCGACTTCTA ACAGTGGACA TTACTTCTGT TGTGTCAAAG CTGGTCATGG GAAGTGGTAC 
AAGATGGATG ATACTAAGGT CACCAGGTGT GATGTGACTT CTGTCCTGAA TGAGAATGCC 
TATGTGCTCT TCTATGTGCA GCAGACCGAC CTCAAACAGG TCAGTATTGA CATGCCAGAG 
GGCAGAGTAC ATGAGGTTCT TGACCCTAAA TACCAGCTGA AGAAATCCCG GAGAAAAAAG 
CGTAAGAAGC AATGCCATTG CACAGATGAT GCCGGAGAGG CATGCGAAAA CAGGGAGAAG 
AGAGCAAAGA AAGAAACCTC CTTAGGGGAG GGGAAAGTGC CTCAGGAAGT GAACCACGAG 
AAAGCTGGGC AGAAACATGG GAATACCAAA CTCGTGCCTC AGGAACAGAA CCACCAGAGA 
GCTGGGCAGA ACCTCAGGAA TACTGAAGTT GAACTTGATC TGCCTGTTGA TGCAATTGTG 
ATTCACCAGC CCAGATCCAC AGCAAACTGG GGCACGGATG CTCCAGACAA AGAGAATCAA 
CCCTGGCACA ATGGTGACAG GCTCCTCACC TCTCAGGGCC TCATGAGCCC TGGGCAGCTC 
TGTAGTCAGG GTGGGAGATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011240180.1
CDS	1..1521
Translation	MVVSLSFPEADPALSSPDAPELHQDEAQVVEELTTNGKHSLSWESPQGPGCGLQNTGNSCYLNAALQCLTHTPPLADYMLSQEHSQTCCSPEGCKMCAMEAHVTQSLLHSHSGDVMKPSQILTSAFHKHQQEDAHEFLMFTLETMHESCLQVHRQSDPTPQDTSPIHDIFGGWWRSQIKCLHCQGTSHTFDPFLDVPLDISSAQSVNQALWDTGKSEELLGENAYYCGRCRQKMPASKTLHVHIAPKVLLLVLKRFSAFTGNKLDRKVSYPEFLDLKPYLSEPTGGPLPYALYAVLVHDGATSNSGHYFCCVKAGHGKWYKMDDTKVTRCDVTSVLNENAYVLFYVQQTDLKQVSIDMPEGRVHEVLDPKYQLKKSRRKKRKKQCHCTDDAGEACENREKRAKKETSLGEGKVPQEVNHEKAGQKHGNTKLVPQEQNHQRAGQNLRNTEVELDLPVDAIVIHQPRSTANWGTDAPDKENQPWHNGDRLLTSQGLMSPGQLCSQGGR

Target ORF information:

RefSeq Version	XM_011241878.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus ubiquitin specific peptidase 17-like E (Usp17le), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011241878.2

ORF Insert Sequence:

ATGGTGGTTT CTCTTTCCTT CCCAGAAGCA GATCCAGCAC TATCATCTCC TGATGCCCCA 
GAGCTGCATC AGGATGAAGC TCAGGTGGTG GAGGAGCTAA CTACCAATGG AAAGCACAGT 
CTGAGTTGGG AGAGTCCCCA AGGACCAGGA TGCGGGCTCC AGAACACAGG CAACAGCTGC 
TACCTGAACG CAGCCCTGCA GTGCTTGACA CACACACCAC CTCTAGCTGA CTACATGCTG 
TCCCAGGAGC ACAGTCAAAC CTGTTGTTCC CCAGAAGGCT GTAAGATGTG TGCTATGGAA 
GCCCATGTGA CCCAGAGTCT CCTGCACTCT CACTCGGGGG ATGTCATGAA GCCCTCCCAG 
ATTTTGACCT CTGCCTTCCA CAAGCACCAG CAGGAAGATG CCCATGAGTT TCTCATGTTC 
ACCTTGGAAA CAATGCATGA ATCCTGCCTT CAAGTGCACA GACAATCAGA TCCCACCCCT 
CAGGATACGT CACCCATTCA TGACATATTT GGAGGCTGGT GGAGGTCTCA GATCAAGTGT 
CTCCATTGCC AGGGCACCTC ACATACCTTC GATCCCTTCC TGGATGTCCC CCTGGATATC 
AGCTCAGCTC AGAGTGTAAA TCAAGCCTTG TGGGATACAG GGAAGTCAGA AGAGCTACTT 
GGAGAGAATG CCTACTACTG TGGTAGGTGT AGACAGAAGA TGCCAGCTTC TAAGACCCTG 
CATGTTCATA TTGCTCCAAA GGTACTCCTG CTAGTGTTAA AGCGCTTCTC AGCCTTCACG 
GGTAACAAGT TAGACAGAAA AGTAAGCTAC CCGGAGTTCC TTGACCTGAA GCCATACCTG 
TCTGAGCCTA CTGGAGGACC TTTGCCTTAT GCCCTCTATG CCGTCCTGGT CCATGATGGT 
GCGACTTCTA ACAGTGGACA TTACTTCTGT TGTGTCAAAG CTGGTCATGG GAAGTGGTAC 
AAGATGGATG ATACTAAGGT CACCAGGTGT GATGTGACTT CTGTCCTGAA TGAGAATGCC 
TATGTGCTCT TCTATGTGCA GCAGACCGAC CTCAAACAGG TCAGTATTGA CATGCCAGAG 
GGCAGAGTAC ATGAGGTTCT TGACCCTAAA TACCAGCTGA AGAAATCCCG GAGAAAAAAG 
CGTAAGAAGC AATGCCATTG CACAGATGAT GCCGGAGAGG CATGCGAAAA CAGGGAGAAG 
AGAGCAAAGA AAGAAACCTC CTTAGGGGAG GGGAAAGTGC CTCAGGAAGT GAACCACGAG 
AAAGCTGGGC AGAAACATGG GAATACCAAA CTCGTGCCTC AGGAACAGAA CCACCAGAGA 
GCTGGGCAGA ACCTCAGGAA TACTGAAGTT GAACTTGATC TGCCTGTTGA TGCAATTGTG 
ATTCACCAGC CCAGATCCAC AGCAAACTGG GGCACGGATG CTCCAGACAA AGAGAATCAA 
CCCTGGCACA ATGGTGACAG GCTCCTCACC TCTCAGGGCC TCATGAGCCC TGGGCAGCTC 
TGTAGTCAGG GTGGGAGATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Usp17le ( XM_017322434.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017177923.1 Mus musculus ubiquitin specific peptidase 17-like E (Usp17le), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu82171
Clone ID Related Accession (Same CDS sequence)	XM_017322434.1
Accession Version	XM_017322434.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1623bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	ubiquitin carboxyl-terminal hydrolase 17-like protein E isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGTTTG CACGTTCCTT CCCAGAAGAG ACTGGAGGGG AAAATCTTCC TTCTGCTCCC 
TTAGAAGACT CCAGCAAGTT CTTTGAAGAG GTCTTTGGAG ACATGGTGGT TGCTCTTTCC 
TTCCCAGAAG CAGATCCAGC ACTATCATCT CCTGATGCCC CAGAGCTGCA TCAGGATGAA 
GCTCAGGTGG TGGAGGAGCT AACTACCAAT GGAAAGCACA GTCTGAGTTG GGAGAGTCCC 
CAAGGACCAG GATGCGGGCT CCAGAACACA GGCAACAGCT GCTACCTGAA CGCAGCCCTG 
CAGTGCTTGA CACACACACC ACCTCTAGCT GACTACATGC TGTCCCAGGA GCACAGTCAA 
ACCTGTTGTT CCCCAGAAGG CTGTAAGATG TGTGCTATGG AAGCCCATGT GACCCAGAGT 
CTCCTGCACT CTCACTCGGG GGATGTCATG AAGCCCTCCC AGATTTTGAC CTCTGCCTTC 
CACAAGCACC AGCAGGAAGA TGCCCATGAG TTTCTCATGT TCACCTTGGA AACAATGCAT 
GAATCCTGCC TTCAAGTGCA CAGACAATCA GATCCCACCC CTCAGGATAC GTCACCCATT 
CATGACATAT TTGGAGGCTG GTGGAGGTCT CAGATCAAGT GTCTCCATTG CCAGGGCACC 
TCACATACCT TCGATCCCTT CCTGGATGTC CCCCTGGATA TCAGCTCAGC TCAGAGTGTA 
AATCAAGCCT TGTGGGATAC AGGGAAGTCA GAAGAGCTAC TTGGAGAGAA TGCCTACTAC 
TGTGGTAGGT GTAGACAGAA GATGCCAGCT TCTAAGACCC TGCATGTTCA TATTGCTCCA 
AAGGTACTCC TGCTAGTGTT AAAGCGCTTC TCAGCCTTCA CGGGTAACAA GTTAGACAGA 
AAAGTAAGCT ACCCGGAGTT CCTTGACCTG AAGCCATACC TGTCTGAGCC TACTGGAGGA 
CCTTTGCCTT ATGCCCTCTA TGCCGTCCTG GTCCATGATG GTGCGACTTC TAACAGTGGA 
CATTACTTCT GTTGTGTCAA AGCTGGTCAT GGGAAGTGGT ACAAGATGGA TGATACTAAG 
GTCACCAGGT GTGATGTGAC TTCTGTCCTG AATGAGAATG CCTATGTGCT CTTCTATGTG 
CAGCAGACCG ACCTCAAACA GGTCAGTATT GACATGCCAG AGGGCAGAGT ACATGAGGTT 
CTTGACCCTA AATACCAGCT GAAGAAATCC CGGAGAAAAA AGCGTAAGAA GCAATGCCAT 
TGCACAGATG ATGCCGGAGA GGCATGCGAA AACAGGGAGA AGAGAGCAAA GAAAGAAACC 
TCCTTAGGGG AGGGGAAAGT GCCTCAGGAA GTGAACCACG AGAAAGCTGG GCAGAAACAT 
GGGAATACCA AACTCGTGCC TCAGGAACAG AACCACCAGA GAGCTGGGCA GAACCTCAGG 
AATACTGAAG TTGAACTTGA TCTGCCTGTT GATGCAATTG TGATTCACCA GCCCAGATCC 
ACAGCAAACT GGGGCACGGA TGCTCCAGAC AAAGAGAATC AACCCTGGCA CAATGGTGAC 
AGGCTCCTCA CCTCTCAGGG CCTCATGAGC CCTGGGCAGC TCTGTAGTCA GGGTGGGAGA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017177923.1
CDS	67..1689
Translation	MVFARSFPEETGGENLPSAPLEDSSKFFEEVFGDMVVALSFPEADPALSSPDAPELHQDEAQVVEELTTNGKHSLSWESPQGPGCGLQNTGNSCYLNAALQCLTHTPPLADYMLSQEHSQTCCSPEGCKMCAMEAHVTQSLLHSHSGDVMKPSQILTSAFHKHQQEDAHEFLMFTLETMHESCLQVHRQSDPTPQDTSPIHDIFGGWWRSQIKCLHCQGTSHTFDPFLDVPLDISSAQSVNQALWDTGKSEELLGENAYYCGRCRQKMPASKTLHVHIAPKVLLLVLKRFSAFTGNKLDRKVSYPEFLDLKPYLSEPTGGPLPYALYAVLVHDGATSNSGHYFCCVKAGHGKWYKMDDTKVTRCDVTSVLNENAYVLFYVQQTDLKQVSIDMPEGRVHEVLDPKYQLKKSRRKKRKKQCHCTDDAGEACENREKRAKKETSLGEGKVPQEVNHEKAGQKHGNTKLVPQEQNHQRAGQNLRNTEVELDLPVDAIVIHQPRSTANWGTDAPDKENQPWHNGDRLLTSQGLMSPGQLCSQGGR

Target ORF information:

RefSeq Version	XM_017322434.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus ubiquitin specific peptidase 17-like E (Usp17le), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017322434.1

ORF Insert Sequence:

ATGGTGTTTG CACGTTCCTT CCCAGAAGAG ACTGGAGGGG AAAATCTTCC TTCTGCTCCC 
TTAGAAGACT CCAGCAAGTT CTTTGAAGAG GTCTTTGGAG ACATGGTGGT TGCTCTTTCC 
TTCCCAGAAG CAGATCCAGC ACTATCATCT CCTGATGCCC CAGAGCTGCA TCAGGATGAA 
GCTCAGGTGG TGGAGGAGCT AACTACCAAT GGAAAGCACA GTCTGAGTTG GGAGAGTCCC 
CAAGGACCAG GATGCGGGCT CCAGAACACA GGCAACAGCT GCTACCTGAA CGCAGCCCTG 
CAGTGCTTGA CACACACACC ACCTCTAGCT GACTACATGC TGTCCCAGGA GCACAGTCAA 
ACCTGTTGTT CCCCAGAAGG CTGTAAGATG TGTGCTATGG AAGCCCATGT GACCCAGAGT 
CTCCTGCACT CTCACTCGGG GGATGTCATG AAGCCCTCCC AGATTTTGAC CTCTGCCTTC 
CACAAGCACC AGCAGGAAGA TGCCCATGAG TTTCTCATGT TCACCTTGGA AACAATGCAT 
GAATCCTGCC TTCAAGTGCA CAGACAATCA GATCCCACCC CTCAGGATAC GTCACCCATT 
CATGACATAT TTGGAGGCTG GTGGAGGTCT CAGATCAAGT GTCTCCATTG CCAGGGCACC 
TCACATACCT TCGATCCCTT CCTGGATGTC CCCCTGGATA TCAGCTCAGC TCAGAGTGTA 
AATCAAGCCT TGTGGGATAC AGGGAAGTCA GAAGAGCTAC TTGGAGAGAA TGCCTACTAC 
TGTGGTAGGT GTAGACAGAA GATGCCAGCT TCTAAGACCC TGCATGTTCA TATTGCTCCA 
AAGGTACTCC TGCTAGTGTT AAAGCGCTTC TCAGCCTTCA CGGGTAACAA GTTAGACAGA 
AAAGTAAGCT ACCCGGAGTT CCTTGACCTG AAGCCATACC TGTCTGAGCC TACTGGAGGA 
CCTTTGCCTT ATGCCCTCTA TGCCGTCCTG GTCCATGATG GTGCGACTTC TAACAGTGGA 
CATTACTTCT GTTGTGTCAA AGCTGGTCAT GGGAAGTGGT ACAAGATGGA TGATACTAAG 
GTCACCAGGT GTGATGTGAC TTCTGTCCTG AATGAGAATG CCTATGTGCT CTTCTATGTG 
CAGCAGACCG ACCTCAAACA GGTCAGTATT GACATGCCAG AGGGCAGAGT ACATGAGGTT 
CTTGACCCTA AATACCAGCT GAAGAAATCC CGGAGAAAAA AGCGTAAGAA GCAATGCCAT 
TGCACAGATG ATGCCGGAGA GGCATGCGAA AACAGGGAGA AGAGAGCAAA GAAAGAAACC 
TCCTTAGGGG AGGGGAAAGT GCCTCAGGAA GTGAACCACG AGAAAGCTGG GCAGAAACAT 
GGGAATACCA AACTCGTGCC TCAGGAACAG AACCACCAGA GAGCTGGGCA GAACCTCAGG 
AATACTGAAG TTGAACTTGA TCTGCCTGTT GATGCAATTG TGATTCACCA GCCCAGATCC 
ACAGCAAACT GGGGCACGGA TGCTCCAGAC AAAGAGAATC AACCCTGGCA CAATGGTGAC 
AGGCTCCTCA CCTCTCAGGG CCTCATGAGC CCTGGGCAGC TCTGTAGTCA GGGTGGGAGA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1.
Nature communications813923(2017 Jan)
Liu T,Yu J,Deng M,Yin Y,Zhang H,Luo K,Qin B,Li Y,Wu C,Ren T,Han Y,Yin P,Kim J,Lee S,Lin J,Zhang L,Zhang J,Nowsheen S,Wang L,Boughey J,Goetz MP,Yuan J,Lou Z

Cell cycle-dependent expression of Dub3, Nanog and the p160 family of nuclear receptor coactivators (NCoAs) in mouse embryonic stem cells.
PloS one9(4)e93663(2014)
van der Laan S,Golfetto E,Vanacker JM,Maiorano D

High Dub3 expression in mouse ESCs couples the G1/S checkpoint to pluripotency.
Molecular cell52(3)366-79(2013 Nov)
van der Laan S,Tsanov N,Crozet C,Maiorano D

Polyclonal and monoclonal antibodies specific for USP17, a proapoptotic deubiquitinating enzyme.
Hybridoma (2005)29(4)311-9(2010 Aug)
Ramakrishna S,Suresh B,Kang IC,Baek KH

The DUB/USP17 deubiquitinating enzymes: a gene family within a tandemly repeated sequence, is also embedded within the copy number variable beta-defensin cluster.
BMC genomics11250(2010 Apr)
Burrows JF,Scott CJ,Johnston JA