Prlh cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Prlh
Entrez Gene ID	623503
Full Name	prolactin releasing hormone
Synonyms	EG623503
General protein information	Preferred Names prolactin releasing hormone Names prolactin-releasing peptide
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1\|1 D

mRNA and Protein(s)

mRNA	Protein	Name
XM_006529772.1	XP_006529835.1	prolactin-releasing peptide isoform X1
NM_001101647.1	NP_001095117.1	prolactin-releasing peptide precursor
XM_006529772.2	XP_006529835.1	prolactin-releasing peptide isoform X1

Pathways from BioSystems

Homologies

	PRLH	XP_001084860.1
Homo sapiens (human)	PRLH	NP_056977.1
Mus musculus (house mouse)	Prlh	NP_001095117.1
Rattus norvegicus (Norway rat)	Prlh	NP_071558.1

Gene Ontology
Bibliography

Related articles in PubMed

The thermogenic effect of leptin is dependent on a distinct population of prolactin-releasing peptide neurons in the dorsomedial hypothalamus.
Dodd GT, Worth AA, Nunn N, Korpal AK, Bechtold DA, Allison MB, Myers MG Jr, Statnick MA, Luckman SM
Cell metabolism20(4)639-49(2014 Oct)

The medial amygdala-medullary PrRP-synthesizing neuron pathway mediates neuroendocrine responses to contextual conditioned fear in male rodents.
Yoshida M, Takayanagi Y, Onaka T
Endocrinology155(8)2996-3004(2014 Aug)

Acetylation of Prrp K150 regulates the subcellular localization.
Sasaki K, Suzuki A, Kagatsume S, Ono M, Matsuzawa K, Taguchi Y, Kurihara Y
Gene491(1)13-9(2012 Jan)

Blockade of PrRP attenuates MPTP-induced toxicity in mice.
Sun B, Mochiduki A, Nakamura K, Yokoyama K, Adachi S, Fujiwara K, Matsumoto H, Inoue K
Peptides30(7)1267-75(2009 Jul)

Invariant NKT cells reduce the immunosuppressive activity of influenza A virus-induced myeloid-derived suppressor cells in mice and humans.
De Santo C, Salio M, Masri SH, Lee LY, Dong T, Speak AO, Porubsky S, Booth S, Veerapen N, Besra GS, Gr?ne HJ, Platt FM, Zambon M, Cerundolo V
The Journal of clinical investigation118(12)4036-48(2008 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The medial amygdala-medullary PrRP-synthesizing neuron pathway plays an important role in neuroendocrine responses to contextual conditioned fear
Title: The medial amygdala-medullary PrRP-synthesizing neuron pathway mediates neuroendocrine responses to contextual conditioned fear in male rodents.

Data report that PrRP and its receptor, GPR10, were found in the mouse substantia nigra pars compacta (SNpc), the main location of dopaminergic (DA) neurons of the nigrostriatal system.
Title: Blockade of PrRP attenuates MPTP-induced toxicity in mice.

These results suggest that p53 may regulate the differentiation of trophoblast giant cells, and may control the physiological PrRP stimuli in mouse placentas.
Title: Increase of the trophoblast giant cells with prolactin-releasing peptide (PrRP) receptor expression in p53-null mice.

The following Prlh gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Prlh cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu03669	NM_001101647.1 Latest version!	Mus musculus prolactin releasing hormone (Prlh), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu03669	XM_006529772.2 Latest version!	Mus musculus prolactin releasing hormone (Prlh), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OMu03669	XM_006529772.1	Mus musculus prolactin releasing hormone (Prlh), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Prlh ( NM_001101647.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001095117.1 Mus musculus prolactin releasing hormone (Prlh), mRNA.

Price & Availability↑

CloneID	OMu03669
Clone ID Related Accession (Same CDS sequence)	XM_006529772.1 , NM_001101647.1 , XM_006529772.2
Accession Version	NM_001101647.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 261bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-25
Organism	Mus musculus(house mouse)
Product	prolactin-releasing peptide precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC118682.8. On or before Nov 16, 2007 this sequence version replaced XM_907371.1, XM_887970.1. Sequence Note: This RefSeq record was created using genomic sequence from the reference genome strain, C57BL/6J. The transcript and the encoded protein are supported by orthologous human and rat data. ##Evidence-Data-START## Transcript exon combination :: FJ424613.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END##

ATGGCACCGA GGACCTGGCT TCTGTGCTTG CTGCTGCTAG GCTTAGTCCT CCCAGGAGCT 
TCCAGCCGAG CCCACCAGCA CTCCATGGAG ACCCGCACCC CTGACATCAA TCCTGCCTGG 
TACACGGGTC GTGGGATCAG GCCTGTGGGC CGCTTCGGGA GGAGGAGGGC AGCCCTGAGG 
GATGTCACCG GACCTGGCCT GCGGTGCCGG CTAAGCTGCT TCCCACTGGA TGGAAGTGCC 
AAGTTCTCTC ACAGCTCATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001095117.1
CDS	1..261
Translation	MAPRTWLLCLLLLGLVLPGASSRAHQHSMETRTPDINPAWYTGRGIRPVGRFGRRRAALRDVTGPGLRCRLSCFPLDGSAKFSHSS

Target ORF information:

RefSeq Version	NM_001101647.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus prolactin releasing hormone (Prlh), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001101647.1

ORF Insert Sequence:

ATGGCACCGA GGACCTGGCT TCTGTGCTTG CTGCTGCTAG GCTTAGTCCT CCCAGGAGCT 
TCCAGCCGAG CCCACCAGCA CTCCATGGAG ACCCGCACCC CTGACATCAA TCCTGCCTGG 
TACACGGGTC GTGGGATCAG GCCTGTGGGC CGCTTCGGGA GGAGGAGGGC AGCCCTGAGG 
GATGTCACCG GACCTGGCCT GCGGTGCCGG CTAAGCTGCT TCCCACTGGA TGGAAGTGCC 
AAGTTCTCTC ACAGCTCATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Prlh ( XM_006529772.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006529835.1 Mus musculus prolactin releasing hormone (Prlh), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu03669
Clone ID Related Accession (Same CDS sequence)	XM_006529772.1 , NM_001101647.1 , XM_006529772.2
Accession Version	XM_006529772.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 261bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	prolactin-releasing peptide isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCACCGA GGACCTGGCT TCTGTGCTTG CTGCTGCTAG GCTTAGTCCT CCCAGGAGCT 
TCCAGCCGAG CCCACCAGCA CTCCATGGAG ACCCGCACCC CTGACATCAA TCCTGCCTGG 
TACACGGGTC GTGGGATCAG GCCTGTGGGC CGCTTCGGGA GGAGGAGGGC AGCCCTGAGG 
GATGTCACCG GACCTGGCCT GCGGTGCCGG CTAAGCTGCT TCCCACTGGA TGGAAGTGCC 
AAGTTCTCTC ACAGCTCATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006529835.1
CDS	662..922
Translation	MAPRTWLLCLLLLGLVLPGASSRAHQHSMETRTPDINPAWYTGRGIRPVGRFGRRRAALRDVTGPGLRCRLSCFPLDGSAKFSHSS

Target ORF information:

RefSeq Version	XM_006529772.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus prolactin releasing hormone (Prlh), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006529772.1

ORF Insert Sequence:

ATGGCACCGA GGACCTGGCT TCTGTGCTTG CTGCTGCTAG GCTTAGTCCT CCCAGGAGCT 
TCCAGCCGAG CCCACCAGCA CTCCATGGAG ACCCGCACCC CTGACATCAA TCCTGCCTGG 
TACACGGGTC GTGGGATCAG GCCTGTGGGC CGCTTCGGGA GGAGGAGGGC AGCCCTGAGG 
GATGTCACCG GACCTGGCCT GCGGTGCCGG CTAAGCTGCT TCCCACTGGA TGGAAGTGCC 
AAGTTCTCTC ACAGCTCATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Prlh ( XM_006529772.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006529835.1 Mus musculus prolactin releasing hormone (Prlh), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu03669
Clone ID Related Accession (Same CDS sequence)	XM_006529772.1 , NM_001101647.1 , XM_006529772.2
Accession Version	XM_006529772.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 261bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	prolactin-releasing peptide isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006529772.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCACCGA GGACCTGGCT TCTGTGCTTG CTGCTGCTAG GCTTAGTCCT CCCAGGAGCT 
TCCAGCCGAG CCCACCAGCA CTCCATGGAG ACCCGCACCC CTGACATCAA TCCTGCCTGG 
TACACGGGTC GTGGGATCAG GCCTGTGGGC CGCTTCGGGA GGAGGAGGGC AGCCCTGAGG 
GATGTCACCG GACCTGGCCT GCGGTGCCGG CTAAGCTGCT TCCCACTGGA TGGAAGTGCC 
AAGTTCTCTC ACAGCTCATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006529835.1
CDS	209..469
Translation	MAPRTWLLCLLLLGLVLPGASSRAHQHSMETRTPDINPAWYTGRGIRPVGRFGRRRAALRDVTGPGLRCRLSCFPLDGSAKFSHSS

Target ORF information:

RefSeq Version	XM_006529772.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus prolactin releasing hormone (Prlh), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006529772.2

ORF Insert Sequence:

ATGGCACCGA GGACCTGGCT TCTGTGCTTG CTGCTGCTAG GCTTAGTCCT CCCAGGAGCT 
TCCAGCCGAG CCCACCAGCA CTCCATGGAG ACCCGCACCC CTGACATCAA TCCTGCCTGG 
TACACGGGTC GTGGGATCAG GCCTGTGGGC CGCTTCGGGA GGAGGAGGGC AGCCCTGAGG 
GATGTCACCG GACCTGGCCT GCGGTGCCGG CTAAGCTGCT TCCCACTGGA TGGAAGTGCC 
AAGTTCTCTC ACAGCTCATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The thermogenic effect of leptin is dependent on a distinct population of prolactin-releasing peptide neurons in the dorsomedial hypothalamus.
Cell metabolism20(4)639-49(2014 Oct)
Dodd GT,Worth AA,Nunn N,Korpal AK,Bechtold DA,Allison MB,Myers MG Jr,Statnick MA,Luckman SM

The medial amygdala-medullary PrRP-synthesizing neuron pathway mediates neuroendocrine responses to contextual conditioned fear in male rodents.
Endocrinology155(8)2996-3004(2014 Aug)
Yoshida M,Takayanagi Y,Onaka T

Acetylation of Prrp K150 regulates the subcellular localization.
Gene491(1)13-9(2012 Jan)
Sasaki K,Suzuki A,Kagatsume S,Ono M,Matsuzawa K,Taguchi Y,Kurihara Y

Blockade of PrRP attenuates MPTP-induced toxicity in mice.
Peptides30(7)1267-75(2009 Jul)
Sun B,Mochiduki A,Nakamura K,Yokoyama K,Adachi S,Fujiwara K,Matsumoto H,Inoue K

Invariant NKT cells reduce the immunosuppressive activity of influenza A virus-induced myeloid-derived suppressor cells in mice and humans.
The Journal of clinical investigation118(12)4036-48(2008 Dec)
De Santo C,Salio M,Masri SH,Lee LY,Dong T,Speak AO,Porubsky S,Booth S,Veerapen N,Besra GS,Gr?ne HJ,Platt FM,Zambon M,Cerundolo V

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Prlh cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム