Adamdec1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Adamdec1
Entrez Gene ID	58860
Full Name	ADAM-like, decysin 1
Synonyms	2210414L24Rik,AI574231,Dcsn
General protein information	Preferred Names ADAM-like, decysin 1 Names ADAM DEC1 ADAM-like protein decysin-1 a disintegrin and metalloproteinase domain-like protein decysin-1 decysin disintegrin metalloprotease (decysin)
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 14 Map Location: 14\|14 D1

mRNA and Protein(s)

mRNA	Protein	Name
NM_021475.2	NP_067450.1	ADAM DEC1 precursor

Pathways from BioSystems

Homologies

	ADAMDEC1	XP_001106842.1
Mus musculus (house mouse)	Adamdec1	NP_067450.1
Homo sapiens (human)	ADAMDEC1	NP_055294.1
Pan troglodytes (chimpanzee)	ADAMDEC1	XP_528092.3
Canis lupus familiaris (dog)	ADAMDEC1	XP_005635754.1

Gene Ontology
Bibliography

Related articles in PubMed

Critical Role of the Disintegrin Metalloprotease ADAM-like Decysin-1 [ADAMDEC1] for Intestinal Immunity and Inflammation.
O'Shea NR, Chew TS, Dunne J, Marnane R, Nedjat-Shokouhi B, Smith PJ, Bloom SL, Smith AM, Segal AW
Journal of Crohn's & colitis10(12)1417-1427(2016 Dec)

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
Liu X, Jiao Y, Cao Y, Deng N, Ma Y, Hasty KA, Kang A, Chen H, Stuart JM, Gu W
BMC immunology17(1)25(2016 08)

Histone H3 lysine 9 methyltransferases, G9a and GLP are essential for cardiac morphogenesis.
Inagawa M, Nakajima K, Makino T, Ogawa S, Kojima M, Ito S, Ikenishi A, Hayashi T, Schwartz RJ, Nakamura K, Obayashi T, Tachibana M, Shinkai Y, Maeda K, Miyagawa-Tomita S, Takeuchi T
Mechanisms of development130(11-12)519-31(2013 Nov-Dec)

Protocadherin 12 deficiency alters morphogenesis and transcriptional profile of the placenta.
Rampon C, Bouillot S, Climescu-Haulica A, Prandini MH, Cand F, Vandenbrouck Y, Huber P
Physiological genomics34(2)193-204(2008 Jul)

Genomic organization of the region spanning D14Mit262 and D14Mit86 on mouse chromosome 14 and exclusion of Adam28 and Adamdec1 as the cataract-causing gene, lr2.
Kim E, Rhee SD, Bae Y, Okumoto M, Yoon JB, Song CW, Yoon SK
Cytogenetic and genome research116(1-2)12-7(2007)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

protects the bowel from chemical and bacterial insults, failure of which may predispose to Crohn's disease
Title: Critical Role of the Disintegrin Metalloprotease ADAM-like Decysin-1 [ADAMDEC1] for Intestinal Immunity and Inflammation.

The following Adamdec1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Adamdec1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu16076	NM_021475.2 Latest version!	Mus musculus ADAM-like, decysin 1 (Adamdec1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$272.30 $389.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Adamdec1 ( NM_021475.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_067450.1 Mus musculus ADAM-like, decysin 1 (Adamdec1), mRNA.

Price & Availability↑

CloneID	OMu16076
Clone ID Related Accession (Same CDS sequence)	NM_021475.2
Accession Version	NM_021475.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1404bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Mus musculus(house mouse)
Product	ADAM DEC1 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CT025563.11 and AC154706.2. On Mar 21, 2007 this sequence version replaced NM_021475.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AJ242912.1, BC026542.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380 [ECO:0000348] ##Evidence-Data-END##

ATGCTGCCTG GGACTTCTCG GCTACCCACA GAAGCCAGCA TGTCTTGGGT CCTGCTTTCA 
GTCCTGTGGC TTATCATTCA AATCCAAGTG ATAGATGCAA CGTTAACCCC CGAGTTAAAG 
CCTCACGAAA TAGTTCGTCC TAAAAAACTA CCCATTTCAC AGAAAAGAGG GCTTGAGAAC 
AACCAGACAG AGAGATATGG CAAAGAGGAA AAATATGCAC CAGAAGTTCA ATATCAGATC 
ATACTAAATG GAGAAGAAAT TGTTTTTCAC CTAAAGAGAA CCAAGCATCT TCTGGGGCCA 
GACTACACTG AAACATCTTA CTCACCCAGA GGAGAAGAGA GCACCAGACA CTCTCAGGAT 
GTGAAACCCT GCTACTATGA AGGCCACATC CAAAATGCAA GGGGCTCTCT GGCCAGGATC 
AGTACCTGTG ATGGGTTGAG AGGGTACTTC ACACATCGTG ATCAGAGATA TCAAATAAAG 
CCTCTACAAA GCACAGATGA GGGAGAGCAT GCTGTTCTCC CATACAGCTG GAAGGGACAA 
GACACAGTTC ATGACAAGGA TGCTGAGAAG CAAGTTGTCA GGAAACGAAG CCATCTTCGA 
ACTTCCAGGT CACTCAAAAA CCCAAATGAA GACTTACTTC AAGGACAGAA GTACATTGGT 
CTCTTTTTGG TGCTGGATAA TGCCTATTAT AAGCTGTATA ATGGGAATGT GACTCAGATG 
AGAACCTTTC TGTTCAAGGT GCTGAATCTG CTCAATATGA TTTATAAAAC CATAAATATT 
CAAGTGTCTT TGGTGGGCAT GGAGATCTGG TCTGACCAGG ACAAGATAAA GGTGGAGCCC 
AACCTTGGTG CCACGTTCAC ACACTTCATG AGATGGCATT ATTCTAACCT GGGGAAAAGG 
ATCCATAACC ACGCCCAGCT TCTCAGTGGA GCTAGCTTCC GCCATGGACG TGTGGGAATG 
GCAGCTGGGA ATTCCTTTTG TACTACATCG TCTGTGTCTG TAATTGAGGC TAAAAAAAAG 
AATAATGTGG CTCTTGTTGC ACTGATGTCA CATGAGTTGG GCCACGCCCT TGGTATGAAG 
GATGTTCCAT ATTATACCAA GTGTCCCTCT GGCAGCTGTG TGATGAATCA GTACCTGAGT 
TCAAAATTCC CCAAGGATTT CAGTACCGTC AGCCGTTCTC ATTTTCAAGG GTTTCTCTCA 
TCTAGAAATG CAAGGTGTCT GCTGCTGGCA CCTGACCCTA AAAACATAAT AAAACCAACA 
TGTGGGAACC AAGTCCTGGA TGTGGGAGAA GAGTGTGACT GTGGCTCTCC TGAGGAATGT 
ACCAATCTTT GCTGTGAGCC CCTGACATGT AGGCTGAAAT CTCAACCTGA CTGCAGTGAA 
GCATCCAACC ACATCACAGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_067450.1
CDS	27..1430
Translation	MLPGTSRLPTEASMSWVLLSVLWLIIQIQVIDATLTPELKPHEIVRPKKLPISQKRGLENNQTERYGKEEKYAPEVQYQIILNGEEIVFHLKRTKHLLGPDYTETSYSPRGEESTRHSQDVKPCYYEGHIQNARGSLARISTCDGLRGYFTHRDQRYQIKPLQSTDEGEHAVLPYSWKGQDTVHDKDAEKQVVRKRSHLRTSRSLKNPNEDLLQGQKYIGLFLVLDNAYYKLYNGNVTQMRTFLFKVLNLLNMIYKTINIQVSLVGMEIWSDQDKIKVEPNLGATFTHFMRWHYSNLGKRIHNHAQLLSGASFRHGRVGMAAGNSFCTTSSVSVIEAKKKNNVALVALMSHELGHALGMKDVPYYTKCPSGSCVMNQYLSSKFPKDFSTVSRSHFQGFLSSRNARCLLLAPDPKNIIKPTCGNQVLDVGEECDCGSPEECTNLCCEPLTCRLKSQPDCSEASNHITE

Target ORF information:

RefSeq Version	NM_021475.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus ADAM-like, decysin 1 (Adamdec1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021475.2

ORF Insert Sequence:

ATGCTGCCTG GGACTTCTCG GCTACCCACA GAAGCCAGCA TGTCTTGGGT CCTGCTTTCA 
GTCCTGTGGC TTATCATTCA AATCCAAGTG ATAGATGCAA CGTTAACCCC CGAGTTAAAG 
CCTCACGAAA TAGTTCGTCC TAAAAAACTA CCCATTTCAC AGAAAAGAGG GCTTGAGAAC 
AACCAGACAG AGAGATATGG CAAAGAGGAA AAATATGCAC CAGAAGTTCA ATATCAGATC 
ATACTAAATG GAGAAGAAAT TGTTTTTCAC CTAAAGAGAA CCAAGCATCT TCTGGGGCCA 
GACTACACTG AAACATCTTA CTCACCCAGA GGAGAAGAGA GCACCAGACA CTCTCAGGAT 
GTGAAACCCT GCTACTATGA AGGCCACATC CAAAATGCAA GGGGCTCTCT GGCCAGGATC 
AGTACCTGTG ATGGGTTGAG AGGGTACTTC ACACATCGTG ATCAGAGATA TCAAATAAAG 
CCTCTACAAA GCACAGATGA GGGAGAGCAT GCTGTTCTCC CATACAGCTG GAAGGGACAA 
GACACAGTTC ATGACAAGGA TGCTGAGAAG CAAGTTGTCA GGAAACGAAG CCATCTTCGA 
ACTTCCAGGT CACTCAAAAA CCCAAATGAA GACTTACTTC AAGGACAGAA GTACATTGGT 
CTCTTTTTGG TGCTGGATAA TGCCTATTAT AAGCTGTATA ATGGGAATGT GACTCAGATG 
AGAACCTTTC TGTTCAAGGT GCTGAATCTG CTCAATATGA TTTATAAAAC CATAAATATT 
CAAGTGTCTT TGGTGGGCAT GGAGATCTGG TCTGACCAGG ACAAGATAAA GGTGGAGCCC 
AACCTTGGTG CCACGTTCAC ACACTTCATG AGATGGCATT ATTCTAACCT GGGGAAAAGG 
ATCCATAACC ACGCCCAGCT TCTCAGTGGA GCTAGCTTCC GCCATGGACG TGTGGGAATG 
GCAGCTGGGA ATTCCTTTTG TACTACATCG TCTGTGTCTG TAATTGAGGC TAAAAAAAAG 
AATAATGTGG CTCTTGTTGC ACTGATGTCA CATGAGTTGG GCCACGCCCT TGGTATGAAG 
GATGTTCCAT ATTATACCAA GTGTCCCTCT GGCAGCTGTG TGATGAATCA GTACCTGAGT 
TCAAAATTCC CCAAGGATTT CAGTACCGTC AGCCGTTCTC ATTTTCAAGG GTTTCTCTCA 
TCTAGAAATG CAAGGTGTCT GCTGCTGGCA CCTGACCCTA AAAACATAAT AAAACCAACA 
TGTGGGAACC AAGTCCTGGA TGTGGGAGAA GAGTGTGACT GTGGCTCTCC TGAGGAATGT 
ACCAATCTTT GCTGTGAGCC CCTGACATGT AGGCTGAAAT CTCAACCTGA CTGCAGTGAA 
GCATCCAACC ACATCACAGA ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Critical Role of the Disintegrin Metalloprotease ADAM-like Decysin-1 [ADAMDEC1] for Intestinal Immunity and Inflammation.
Journal of Crohn's & colitis10(12)1417-1427(2016 Dec)
O'Shea NR,Chew TS,Dunne J,Marnane R,Nedjat-Shokouhi B,Smith PJ,Bloom SL,Smith AM,Segal AW

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
BMC immunology17(1)25(2016 08)
Liu X,Jiao Y,Cao Y,Deng N,Ma Y,Hasty KA,Kang A,Chen H,Stuart JM,Gu W

Histone H3 lysine 9 methyltransferases, G9a and GLP are essential for cardiac morphogenesis.
Mechanisms of development130(11-12)519-31(2013 Nov-Dec)
Inagawa M,Nakajima K,Makino T,Ogawa S,Kojima M,Ito S,Ikenishi A,Hayashi T,Schwartz RJ,Nakamura K,Obayashi T,Tachibana M,Shinkai Y,Maeda K,Miyagawa-Tomita S,Takeuchi T

Protocadherin 12 deficiency alters morphogenesis and transcriptional profile of the placenta.
Physiological genomics34(2)193-204(2008 Jul)
Rampon C,Bouillot S,Climescu-Haulica A,Prandini MH,Cand F,Vandenbrouck Y,Huber P

Genomic organization of the region spanning D14Mit262 and D14Mit86 on mouse chromosome 14 and exclusion of Adam28 and Adamdec1 as the cataract-causing gene, lr2.
Cytogenetic and genome research116(1-2)12-7(2007)
Kim E,Rhee SD,Bae Y,Okumoto M,Yoon JB,Song CW,Yoon SK