Ccl26 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ccl26
Entrez Gene ID	541307
Full Name	chemokine (C-C motif) ligand 26
Synonyms	Ccl26l
General protein information	Preferred Names chemokine (C-C motif) ligand 26 Names C-C motif chemokine 26 eotaxin-3
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 5 Map Location: 5\|5 G2

mRNA and Protein(s)

mRNA	Protein	Name
NM_001013412.2	NP_001013430.2	C-C motif chemokine 26 precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Ccl26	NP_001013430.2
Rattus norvegicus (Norway rat)	Ccl26	NP_001102958.1

Gene Ontology
Bibliography

Related articles in PubMed

Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program.
Sundberg JP, Dadras SS, Silva KA, Kennedy VE, Garland G, Murray SA, Sundberg BA, Schofield PN, Pratt CH
PloS one12(7)e0180682(2017)

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

Puerarin attenuates airway inflammation by regulation of eotaxin-3.
Wang J, Zhang T, Ma C, Wang S
Immunology letters163(2)173-8(2015 Feb)

Alanine scanning mutagenesis of the chemokine receptor CCR3 reveals distinct extracellular residues involved in recognition of the eotaxin family of chemokines.
Duchesnes CE, Murphy PM, Williams TJ, Pease JE
Molecular immunology43(8)1221-31(2006 Mar)

Identification of a cooperative mechanism involving interleukin-13 and eotaxin-2 in experimental allergic lung inflammation.
Pope SM, Fulkerson PC, Blanchard C, Akei HS, Nikolaidis NM, Zimmermann N, Molkentin JD, Rothenberg ME
The Journal of biological chemistry280(14)13952-61(2005 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data indicate that puerarin attenuates airway inflammation via eotaxin-3.
Title: Puerarin attenuates airway inflammation by regulation of eotaxin-3.

Distinct acidic and basic residues within CCR3 determine both receptor expression and activation by the eotaxins.
Title: Alanine scanning mutagenesis of the chemokine receptor CCR3 reveals distinct extracellular residues involved in recognition of the eotaxin family of chemokines.

The following Ccl26 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ccl26 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu25269	NM_001013412.2 Latest version!	Mus musculus chemokine (C-C motif) ligand 26 (Ccl26), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ccl26 ( NM_001013412.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001013430.2 Mus musculus chemokine (C-C motif) ligand 26 (Ccl26), mRNA.

Price & Availability↑

CloneID	OMu25269
Clone ID Related Accession (Same CDS sequence)	NM_001013412.2
Accession Version	NM_001013412.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 282bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Mus musculus(house mouse)
Product	C-C motif chemokine 26 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC083858.3. On Aug 29, 2006 this sequence version replaced NM_001013412.1. ##Evidence-Data-START## Transcript exon combination :: AY587128.1 [ECO:0000332] ##Evidence-Data-END##

ATGTTCTTCG ATTTGGGTCT CCTTGTTCTC CTGGCCATCT TCCTCAGTGT CCAGCTTGGT 
GTTGCCACAT GTGGGAGCAG CATCGCTATG TCCTGCTGCC CTAATTTCAG CTACTATGTG 
ATCCCATGGA GCTGGGTGTA CAGCTATAAG TTCACCGACA AGAGCTGCAC CAGTGACGGT 
GTGATATTCT TTACAAAAAC AGGTAAGCAA TTCTGTGTCC AGCCAGGGGC CAAATGGGTG 
CAGAGATTCA TCTCTCTGGT GAACACCAGG AACCATTTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001013430.2
CDS	1..282
Translation	MFFDLGLLVLLAIFLSVQLGVATCGSSIAMSCCPNFSYYVIPWSWVYSYKFTDKSCTSDGVIFFTKTGKQFCVQPGAKWVQRFISLVNTRNHL

Target ORF information:

RefSeq Version	NM_001013412.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus chemokine (C-C motif) ligand 26 (Ccl26), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001013412.2

ORF Insert Sequence:

ATGTTCTTCG ATTTGGGTCT CCTTGTTCTC CTGGCCATCT TCCTCAGTGT CCAGCTTGGT 
GTTGCCACAT GTGGGAGCAG CATCGCTATG TCCTGCTGCC CTAATTTCAG CTACTATGTG 
ATCCCATGGA GCTGGGTGTA CAGCTATAAG TTCACCGACA AGAGCTGCAC CAGTGACGGT 
GTGATATTCT TTACAAAAAC AGGTAAGCAA TTCTGTGTCC AGCCAGGGGC CAAATGGGTG 
CAGAGATTCA TCTCTCTGGT GAACACCAGG AACCATTTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program.
PloS one12(7)e0180682(2017)
Sundberg JP,Dadras SS,Silva KA,Kennedy VE,Garland G,Murray SA,Sundberg BA,Schofield PN,Pratt CH

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

Puerarin attenuates airway inflammation by regulation of eotaxin-3.
Immunology letters163(2)173-8(2015 Feb)
Wang J,Zhang T,Ma C,Wang S

Alanine scanning mutagenesis of the chemokine receptor CCR3 reveals distinct extracellular residues involved in recognition of the eotaxin family of chemokines.
Molecular immunology43(8)1221-31(2006 Mar)
Duchesnes CE,Murphy PM,Williams TJ,Pease JE

Identification of a cooperative mechanism involving interleukin-13 and eotaxin-2 in experimental allergic lung inflammation.
The Journal of biological chemistry280(14)13952-61(2005 Apr)
Pope SM,Fulkerson PC,Blanchard C,Akei HS,Nikolaidis NM,Zimmermann N,Molkentin JD,Rothenberg ME