Kpna7 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Kpna7
Entrez Gene ID	381686
Full Name	karyopherin alpha 7 (importin alpha 8)
Synonyms	AW146299,Gm1055
General protein information	Preferred Names karyopherin alpha 7 (importin alpha 8) Names importin subunit alpha-8 importin alpha 2 karyopherin subunit alpha-7 nuclear transport receptor
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 5 Map Location: 5\|5 G2

mRNA and Protein(s)

mRNA	Protein	Name
XM_017320944.1	XP_017176433.1	importin subunit alpha-8 isoform X2
NM_001347531.1	NP_001334460.1	importin subunit alpha-8 isoform 1
NM_001013774.2	NP_001013796.2	importin subunit alpha-8 isoform 2

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Kpna7	NP_001013796.2
Xenopus tropicalis (tropical clawed frog)	kpna7	NP_001135557.1
Canis lupus familiaris (dog)	KPNA7	XP_005621155.1
Bos taurus (cattle)	KPNA7	NP_001157419.1
Gallus gallus (chicken)	KPNA7	XP_414795.3
Homo sapiens (human)	KPNA7	NP_001139187.1
Pan troglodytes (chimpanzee)	KPNA7	XP_003318657.1
	KPNA7	XP_001093937.2
Rattus norvegicus (Norway rat)	Kpna7	XP_001074637.3
Danio rerio (zebrafish)	kpna7	NP_998235.1

Gene Ontology
Bibliography

Related articles in PubMed

H7N9 Influenza A Virus Exhibits Importin-?7-Mediated Replication in the Mammalian Respiratory Tract.
Bertram S, Thiele S, Dreier C, Resa-Infante P, Preu? A, van Riel D, Mok CKP, Schwalm F, Peiris JSM, Klenk HD, Gabriel G
The American journal of pathology187(4)831-840(2017 Apr)

Changing expression and subcellular distribution of karyopherins during murine oogenesis.
Mihalas BP, Western PS, Loveland KL, McLaughlin EA, Holt JE
Reproduction (Cambridge, England)150(6)485-96(2015 Dec)

Importin ?7 is essential for zygotic genome activation and early mouse development.
Rother F, Shmidt T, Popova E, Krivokharchenko A, H?gel S, Vilianovich L, Ridders M, Tenner K, Alenina N, K?hler M, Hartmann E, Bader M
PloS one6(3)e18310(2011 Mar)

Novel importin-alpha family member Kpna7 is required for normal fertility and fecundity in the mouse.
Hu J, Wang F, Yuan Y, Zhu X, Wang Y, Zhang Y, Kou Z, Wang S, Gao S
The Journal of biological chemistry285(43)33113-22(2010 Oct)

Karyopherin alpha7 (KPNA7), a divergent member of the importin alpha family of nuclear import receptors.
Kelley JB, Talley AM, Spencer A, Gioeli D, Paschal BM
BMC cell biology1163(2010 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

a decreased H7N9 influenza A virus polymerase activity when importin-alpha7 was silenced by siRNA, is reported.
Title: H7N9 Influenza A Virus Exhibits Importin-?7-Mediated Replication in the Mammalian Respiratory Tract.

knocking out of Kpna7 induced abnormalities of gene expression (dppa2, dppa4, and piwil2) and epigenetic modifications (down-regulation of histone H3K27me3). Biochemical analysis showed that KPNA7 interacts with KPNB1 (importin-beta1).
Title: Novel importin-alpha family member Kpna7 is required for normal fertility and fecundity in the mouse.

a novel importin alpha family member with distinct subcellular localization and nuclear localization signal binding characteristics
Title: Karyopherin alpha7 (KPNA7), a divergent member of the importin alpha family of nuclear import receptors.

The following Kpna7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kpna7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu11606	NM_001013774.2 Latest version!	Mus musculus karyopherin alpha 7 (importin alpha 8) (Kpna7), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu36408	NM_001347531.1 Latest version!	Mus musculus karyopherin alpha 7 (importin alpha 8) (Kpna7), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OMu11606	XM_017320944.1 Latest version!	Mus musculus karyopherin alpha 7 (importin alpha 8) (Kpna7), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Kpna7 ( NM_001013774.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001013796.2 Mus musculus karyopherin alpha 7 (importin alpha 8) (Kpna7), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu11606
Clone ID Related Accession (Same CDS sequence)	XM_017320944.1 , NM_001013774.2
Accession Version	NM_001013774.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1500bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Mus musculus(house mouse)
Product	importin subunit alpha-8 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC113295.5. On Apr 10, 2007 this sequence version replaced NM_001013774.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AY950703.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTACCT CAAAGGCTCC CAAAGAGAGG CTGAAGAACT ATAAGTACCG AGGCAAAGAA 
ATGTCATTGC CACGACAACA GAGGATTGCT TCCAGTCTAC AACTCCGGAA GACCAGGAAA 
GATGAGCAGG TGCTAAAGAG AAGAAATATC GATCTGTTCT CCAGTGACAT GGTTTCTCAA 
GCACTAGTCA AAGAGGTCAA CTTCACTCTG GACGACATCA TCCAAGCGGT GAATAGTTCA 
GATCCAATCC TGCATTTTCG GGCTACCCGG GCTGCCAGGG AAATGATCTC GCAGGAAAAT 
ACCCCTCCTC TCAATTTGAT TATTGAGGCC GGGCTCATTC CCAAGCTGGT GGACTTCCTG 
AAGGCGACAC CTCACCCCAA GCTGCAGTTC GAGGCCGCAT GGGTGCTCAC CAACATTGCC 
TCAGGAACTT CAGAGCAGAC CCGAGCTGTT GTGAAAGAGG GTGCCATTCA GCCCCTGATT 
GAACTCCTCT GTTCCCCACA CCTGACAGTG TCTGAGCAGG CAGTGTGGGC CCTTGGGAAT 
ATCGCTGGAG ACTGTGCAGA ATTCAGAGAC TGTGTCATCT CCAATAATGC CATCCCACAC 
CTGATCAACC TTATTTCAAA AGGCATACCA ATCACATTTC TTCGGAACAT CTCATGGACT 
TTGTCCAACT TATGCCGAAA CAAAGATCCA TATCCCAGTG AGAGCGCCGT GCGGCAGATG 
CTACCTCCCC TCTGTCAACT CCTGCTGCAT CGTGATAATG AGATCCTCGC AGATACCTGC 
TGGGCCCTGT CCTACCTGAC CAAGGGTGGC AAAGAGTATA TCCATCATGT GGTGACCACT 
GGCATCCTGC CCAGGCTTGT AGAGCTTATG ACCAGCTCGG AACTCAGCAT CTCGATACCT 
TGTCTCCACA CTATAGGCAA CATTGTGGCA GGAACAGATG AACAGACCCA GATGGCTATC 
GATGCTGGCA TGCTGAAGGT GTTGGGCCAG GTCCTGAAGC ACCCGAAGAC CTCCATCCAG 
GTGCTGGCTG CCTGGACCAT GAGCAACGTG GCCGCTGGGC CCAGACACCA AGTGGAGCAG 
CTTTTGTGTA ACTTGCTGCC TATTTTGGTA GACCTACTAA GGAATGCAGA ATTAAAAGTC 
CAGAAGGAGG TTGTGTGCAC TGTGATTAAC ATTGCAACAG GAGCCTCTCA GGACCAGCTG 
ACTCTGCTTG CCCACTCGGG AATCTTGGAG CCAATGCTGA GTCTGCTCTC CGCCCCAGAC 
TTGGAGGTGG TCATCATCGT CCTAGACATC ATTTCTTATC TCCTCCAGCA TATAGACAAT 
CTACAAGAGA AGAAAAGGCT GTATTTTCAG ATAGAAAAAT TTGGTGGCTT TGAAAAAATT 
GAGTGTTTAC AGCACCACCA CAACATTTCC ATCAGCAATA GCGCCCTGGA CATCATCGAG 
AAATACTTCT GTGAGGATGG AGATGGTGAC AGTTTGCCCG GGCCTGGGCT GAGAGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001013796.2
CDS	234..1733
Translation	MATSKAPKERLKNYKYRGKEMSLPRQQRIASSLQLRKTRKDEQVLKRRNIDLFSSDMVSQALVKEVNFTLDDIIQAVNSSDPILHFRATRAAREMISQENTPPLNLIIEAGLIPKLVDFLKATPHPKLQFEAAWVLTNIASGTSEQTRAVVKEGAIQPLIELLCSPHLTVSEQAVWALGNIAGDCAEFRDCVISNNAIPHLINLISKGIPITFLRNISWTLSNLCRNKDPYPSESAVRQMLPPLCQLLLHRDNEILADTCWALSYLTKGGKEYIHHVVTTGILPRLVELMTSSELSISIPCLHTIGNIVAGTDEQTQMAIDAGMLKVLGQVLKHPKTSIQVLAAWTMSNVAAGPRHQVEQLLCNLLPILVDLLRNAELKVQKEVVCTVINIATGASQDQLTLLAHSGILEPMLSLLSAPDLEVVIIVLDIISYLLQHIDNLQEKKRLYFQIEKFGGFEKIECLQHHHNISISNSALDIIEKYFCEDGDGDSLPGPGLRV

Target ORF information:

RefSeq Version	NM_001013774.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus karyopherin alpha 7 (importin alpha 8) (Kpna7), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001013774.2

ORF Insert Sequence:

ATGGCTACCT CAAAGGCTCC CAAAGAGAGG CTGAAGAACT ATAAGTACCG AGGCAAAGAA 
ATGTCATTGC CACGACAACA GAGGATTGCT TCCAGTCTAC AACTCCGGAA GACCAGGAAA 
GATGAGCAGG TGCTAAAGAG AAGAAATATC GATCTGTTCT CCAGTGACAT GGTTTCTCAA 
GCACTAGTCA AAGAGGTCAA CTTCACTCTG GACGACATCA TCCAAGCGGT GAATAGTTCA 
GATCCAATCC TGCATTTTCG GGCTACCCGG GCTGCCAGGG AAATGATCTC GCAGGAAAAT 
ACCCCTCCTC TCAATTTGAT TATTGAGGCC GGGCTCATTC CCAAGCTGGT GGACTTCCTG 
AAGGCGACAC CTCACCCCAA GCTGCAGTTC GAGGCCGCAT GGGTGCTCAC CAACATTGCC 
TCAGGAACTT CAGAGCAGAC CCGAGCTGTT GTGAAAGAGG GTGCCATTCA GCCCCTGATT 
GAACTCCTCT GTTCCCCACA CCTGACAGTG TCTGAGCAGG CAGTGTGGGC CCTTGGGAAT 
ATCGCTGGAG ACTGTGCAGA ATTCAGAGAC TGTGTCATCT CCAATAATGC CATCCCACAC 
CTGATCAACC TTATTTCAAA AGGCATACCA ATCACATTTC TTCGGAACAT CTCATGGACT 
TTGTCCAACT TATGCCGAAA CAAAGATCCA TATCCCAGTG AGAGCGCCGT GCGGCAGATG 
CTACCTCCCC TCTGTCAACT CCTGCTGCAT CGTGATAATG AGATCCTCGC AGATACCTGC 
TGGGCCCTGT CCTACCTGAC CAAGGGTGGC AAAGAGTATA TCCATCATGT GGTGACCACT 
GGCATCCTGC CCAGGCTTGT AGAGCTTATG ACCAGCTCGG AACTCAGCAT CTCGATACCT 
TGTCTCCACA CTATAGGCAA CATTGTGGCA GGAACAGATG AACAGACCCA GATGGCTATC 
GATGCTGGCA TGCTGAAGGT GTTGGGCCAG GTCCTGAAGC ACCCGAAGAC CTCCATCCAG 
GTGCTGGCTG CCTGGACCAT GAGCAACGTG GCCGCTGGGC CCAGACACCA AGTGGAGCAG 
CTTTTGTGTA ACTTGCTGCC TATTTTGGTA GACCTACTAA GGAATGCAGA ATTAAAAGTC 
CAGAAGGAGG TTGTGTGCAC TGTGATTAAC ATTGCAACAG GAGCCTCTCA GGACCAGCTG 
ACTCTGCTTG CCCACTCGGG AATCTTGGAG CCAATGCTGA GTCTGCTCTC CGCCCCAGAC 
TTGGAGGTGG TCATCATCGT CCTAGACATC ATTTCTTATC TCCTCCAGCA TATAGACAAT 
CTACAAGAGA AGAAAAGGCT GTATTTTCAG ATAGAAAAAT TTGGTGGCTT TGAAAAAATT 
GAGTGTTTAC AGCACCACCA CAACATTTCC ATCAGCAATA GCGCCCTGGA CATCATCGAG 
AAATACTTCT GTGAGGATGG AGATGGTGAC AGTTTGCCCG GGCCTGGGCT GAGAGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kpna7 ( NM_001347531.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001334460.1 Mus musculus karyopherin alpha 7 (importin alpha 8) (Kpna7), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu36408
Clone ID Related Accession (Same CDS sequence)	NM_001347531.1
Accession Version	NM_001347531.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1563bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-30
Organism	Mus musculus(house mouse)
Product	importin subunit alpha-8 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC113295.5. On Nov 30, 2016 this sequence version replaced XM_017320943.1. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## CDS exon combination :: FJ717333.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMN00849374 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTACCT CAAAGGCTCC CAAAGAGAGG CTGAAGAACT ATAAGTACCG AGGCAAAGAA 
ATGTCATTGC CACGACAACA GAGGATTGCT TCCAGTCTAC AACTCCGGAA GACCAGGAAA 
GATGAGCAGG TGCTAAAGAG AAGAAATATC GATCTGTTCT CCAGTGACAT GGTTTCTCAA 
GCACTAGTCA AAGAGGTCAA CTTCACTCTG GACGACATCA TCCAAGCGGT GAATAGTTCA 
GATCCAATCC TGCATTTTCG GGCTACCCGG GCTGCCAGGG AAATGATCTC GCAGGAAAAT 
ACCCCTCCTC TCAATTTGAT TATTGAGGCC GGGCTCATTC CCAAGCTGGT GGACTTCCTG 
AAGGCGACAC CTCACCCCAA GCTGCAGTTC GAGGCCGCAT GGGTGCTCAC CAACATTGCC 
TCAGGAACTT CAGAGCAGAC CCGAGCTGTT GTGAAAGAGG GTGCCATTCA GCCCCTGATT 
GAACTCCTCT GTTCCCCACA CCTGACAGTG TCTGAGCAGG CAGTGTGGGC CCTTGGGAAT 
ATCGCTGACA GAAAGATGCC AGACACGCAG GTGCAGATCT TTACTCCCAG CACACGGGAG 
GCAAAGGCAG GAGACTGTGC AGAATTCAGA GACTGTGTCA TCTCCAATAA TGCCATCCCA 
CACCTGATCA ACCTTATTTC AAAAGGCATA CCAATCACAT TTCTTCGGAA CATCTCATGG 
ACTTTGTCCA ACTTATGCCG AAACAAAGAT CCATATCCCA GTGAGAGCGC CGTGCGGCAG 
ATGCTACCTC CCCTCTGTCA ACTCCTGCTG CATCGTGATA ATGAGATCCT CGCAGATACC 
TGCTGGGCCC TGTCCTACCT GACCAAGGGT GGCAAAGAGT ATATCCATCA TGTGGTGACC 
ACTGGCATCC TGCCCAGGCT TGTAGAGCTT ATGACCAGCT CGGAACTCAG CATCTCGATA 
CCTTGTCTCC ACACTATAGG CAACATTGTG GCAGGAACAG ATGAACAGAC CCAGATGGCT 
ATCGATGCTG GCATGCTGAA GGTGTTGGGC CAGGTCCTGA AGCACCCGAA GACCTCCATC 
CAGGTGCTGG CTGCCTGGAC CATGAGCAAC GTGGCCGCTG GGCCCAGACA CCAAGTGGAG 
CAGCTTTTGT GTAACTTGCT GCCTATTTTG GTAGACCTAC TAAGGAATGC AGAATTAAAA 
GTCCAGAAGG AGGTTGTGTG CACTGTGATT AACATTGCAA CAGGAGCCTC TCAGGACCAG 
CTGACTCTGC TTGCCCACTC GGGAATCTTG GAGCCAATGC TGAGTCTGCT CTCCGCCCCA 
GACTTGGAGG TGGTCATCAT CGTCCTAGAC ATCATTTCTT ATCTCCTCCA GCATATAGAC 
AATCTACAAG AGAAGAAAAG GCTGTATTTT CAGATAGAAA AATTTGGTGG CTTTGAAAAA 
ATTGAGTGTT TACAGCACCA CCACAACATT TCCATCAGCA ATAGCGCCCT GGACATCATC 
GAGAAATACT TCTGTGAGGA TGGAGATGGT GACAGTTTGC CCGGGCCTGG GCTGAGAGTG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001334460.1
CDS	24..1586
Translation	MATSKAPKERLKNYKYRGKEMSLPRQQRIASSLQLRKTRKDEQVLKRRNIDLFSSDMVSQALVKEVNFTLDDIIQAVNSSDPILHFRATRAAREMISQENTPPLNLIIEAGLIPKLVDFLKATPHPKLQFEAAWVLTNIASGTSEQTRAVVKEGAIQPLIELLCSPHLTVSEQAVWALGNIADRKMPDTQVQIFTPSTREAKAGDCAEFRDCVISNNAIPHLINLISKGIPITFLRNISWTLSNLCRNKDPYPSESAVRQMLPPLCQLLLHRDNEILADTCWALSYLTKGGKEYIHHVVTTGILPRLVELMTSSELSISIPCLHTIGNIVAGTDEQTQMAIDAGMLKVLGQVLKHPKTSIQVLAAWTMSNVAAGPRHQVEQLLCNLLPILVDLLRNAELKVQKEVVCTVINIATGASQDQLTLLAHSGILEPMLSLLSAPDLEVVIIVLDIISYLLQHIDNLQEKKRLYFQIEKFGGFEKIECLQHHHNISISNSALDIIEKYFCEDGDGDSLPGPGLRV

Target ORF information:

RefSeq Version	NM_001347531.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus karyopherin alpha 7 (importin alpha 8) (Kpna7), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001347531.1

ORF Insert Sequence:

ATGGCTACCT CAAAGGCTCC CAAAGAGAGG CTGAAGAACT ATAAGTACCG AGGCAAAGAA 
ATGTCATTGC CACGACAACA GAGGATTGCT TCCAGTCTAC AACTCCGGAA GACCAGGAAA 
GATGAGCAGG TGCTAAAGAG AAGAAATATC GATCTGTTCT CCAGTGACAT GGTTTCTCAA 
GCACTAGTCA AAGAGGTCAA CTTCACTCTG GACGACATCA TCCAAGCGGT GAATAGTTCA 
GATCCAATCC TGCATTTTCG GGCTACCCGG GCTGCCAGGG AAATGATCTC GCAGGAAAAT 
ACCCCTCCTC TCAATTTGAT TATTGAGGCC GGGCTCATTC CCAAGCTGGT GGACTTCCTG 
AAGGCGACAC CTCACCCCAA GCTGCAGTTC GAGGCCGCAT GGGTGCTCAC CAACATTGCC 
TCAGGAACTT CAGAGCAGAC CCGAGCTGTT GTGAAAGAGG GTGCCATTCA GCCCCTGATT 
GAACTCCTCT GTTCCCCACA CCTGACAGTG TCTGAGCAGG CAGTGTGGGC CCTTGGGAAT 
ATCGCTGACA GAAAGATGCC AGACACGCAG GTGCAGATCT TTACTCCCAG CACACGGGAG 
GCAAAGGCAG GAGACTGTGC AGAATTCAGA GACTGTGTCA TCTCCAATAA TGCCATCCCA 
CACCTGATCA ACCTTATTTC AAAAGGCATA CCAATCACAT TTCTTCGGAA CATCTCATGG 
ACTTTGTCCA ACTTATGCCG AAACAAAGAT CCATATCCCA GTGAGAGCGC CGTGCGGCAG 
ATGCTACCTC CCCTCTGTCA ACTCCTGCTG CATCGTGATA ATGAGATCCT CGCAGATACC 
TGCTGGGCCC TGTCCTACCT GACCAAGGGT GGCAAAGAGT ATATCCATCA TGTGGTGACC 
ACTGGCATCC TGCCCAGGCT TGTAGAGCTT ATGACCAGCT CGGAACTCAG CATCTCGATA 
CCTTGTCTCC ACACTATAGG CAACATTGTG GCAGGAACAG ATGAACAGAC CCAGATGGCT 
ATCGATGCTG GCATGCTGAA GGTGTTGGGC CAGGTCCTGA AGCACCCGAA GACCTCCATC 
CAGGTGCTGG CTGCCTGGAC CATGAGCAAC GTGGCCGCTG GGCCCAGACA CCAAGTGGAG 
CAGCTTTTGT GTAACTTGCT GCCTATTTTG GTAGACCTAC TAAGGAATGC AGAATTAAAA 
GTCCAGAAGG AGGTTGTGTG CACTGTGATT AACATTGCAA CAGGAGCCTC TCAGGACCAG 
CTGACTCTGC TTGCCCACTC GGGAATCTTG GAGCCAATGC TGAGTCTGCT CTCCGCCCCA 
GACTTGGAGG TGGTCATCAT CGTCCTAGAC ATCATTTCTT ATCTCCTCCA GCATATAGAC 
AATCTACAAG AGAAGAAAAG GCTGTATTTT CAGATAGAAA AATTTGGTGG CTTTGAAAAA 
ATTGAGTGTT TACAGCACCA CCACAACATT TCCATCAGCA ATAGCGCCCT GGACATCATC 
GAGAAATACT TCTGTGAGGA TGGAGATGGT GACAGTTTGC CCGGGCCTGG GCTGAGAGTG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kpna7 ( XM_017320944.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_017176433.1 Mus musculus karyopherin alpha 7 (importin alpha 8) (Kpna7), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu11606
Clone ID Related Accession (Same CDS sequence)	XM_017320944.1 , NM_001013774.2
Accession Version	XM_017320944.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1500bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	importin subunit alpha-8 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTACCT CAAAGGCTCC CAAAGAGAGG CTGAAGAACT ATAAGTACCG AGGCAAAGAA 
ATGTCATTGC CACGACAACA GAGGATTGCT TCCAGTCTAC AACTCCGGAA GACCAGGAAA 
GATGAGCAGG TGCTAAAGAG AAGAAATATC GATCTGTTCT CCAGTGACAT GGTTTCTCAA 
GCACTAGTCA AAGAGGTCAA CTTCACTCTG GACGACATCA TCCAAGCGGT GAATAGTTCA 
GATCCAATCC TGCATTTTCG GGCTACCCGG GCTGCCAGGG AAATGATCTC GCAGGAAAAT 
ACCCCTCCTC TCAATTTGAT TATTGAGGCC GGGCTCATTC CCAAGCTGGT GGACTTCCTG 
AAGGCGACAC CTCACCCCAA GCTGCAGTTC GAGGCCGCAT GGGTGCTCAC CAACATTGCC 
TCAGGAACTT CAGAGCAGAC CCGAGCTGTT GTGAAAGAGG GTGCCATTCA GCCCCTGATT 
GAACTCCTCT GTTCCCCACA CCTGACAGTG TCTGAGCAGG CAGTGTGGGC CCTTGGGAAT 
ATCGCTGGAG ACTGTGCAGA ATTCAGAGAC TGTGTCATCT CCAATAATGC CATCCCACAC 
CTGATCAACC TTATTTCAAA AGGCATACCA ATCACATTTC TTCGGAACAT CTCATGGACT 
TTGTCCAACT TATGCCGAAA CAAAGATCCA TATCCCAGTG AGAGCGCCGT GCGGCAGATG 
CTACCTCCCC TCTGTCAACT CCTGCTGCAT CGTGATAATG AGATCCTCGC AGATACCTGC 
TGGGCCCTGT CCTACCTGAC CAAGGGTGGC AAAGAGTATA TCCATCATGT GGTGACCACT 
GGCATCCTGC CCAGGCTTGT AGAGCTTATG ACCAGCTCGG AACTCAGCAT CTCGATACCT 
TGTCTCCACA CTATAGGCAA CATTGTGGCA GGAACAGATG AACAGACCCA GATGGCTATC 
GATGCTGGCA TGCTGAAGGT GTTGGGCCAG GTCCTGAAGC ACCCGAAGAC CTCCATCCAG 
GTGCTGGCTG CCTGGACCAT GAGCAACGTG GCCGCTGGGC CCAGACACCA AGTGGAGCAG 
CTTTTGTGTA ACTTGCTGCC TATTTTGGTA GACCTACTAA GGAATGCAGA ATTAAAAGTC 
CAGAAGGAGG TTGTGTGCAC TGTGATTAAC ATTGCAACAG GAGCCTCTCA GGACCAGCTG 
ACTCTGCTTG CCCACTCGGG AATCTTGGAG CCAATGCTGA GTCTGCTCTC CGCCCCAGAC 
TTGGAGGTGG TCATCATCGT CCTAGACATC ATTTCTTATC TCCTCCAGCA TATAGACAAT 
CTACAAGAGA AGAAAAGGCT GTATTTTCAG ATAGAAAAAT TTGGTGGCTT TGAAAAAATT 
GAGTGTTTAC AGCACCACCA CAACATTTCC ATCAGCAATA GCGCCCTGGA CATCATCGAG 
AAATACTTCT GTGAGGATGG AGATGGTGAC AGTTTGCCCG GGCCTGGGCT GAGAGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017176433.1
CDS	125..1624
Translation	MATSKAPKERLKNYKYRGKEMSLPRQQRIASSLQLRKTRKDEQVLKRRNIDLFSSDMVSQALVKEVNFTLDDIIQAVNSSDPILHFRATRAAREMISQENTPPLNLIIEAGLIPKLVDFLKATPHPKLQFEAAWVLTNIASGTSEQTRAVVKEGAIQPLIELLCSPHLTVSEQAVWALGNIAGDCAEFRDCVISNNAIPHLINLISKGIPITFLRNISWTLSNLCRNKDPYPSESAVRQMLPPLCQLLLHRDNEILADTCWALSYLTKGGKEYIHHVVTTGILPRLVELMTSSELSISIPCLHTIGNIVAGTDEQTQMAIDAGMLKVLGQVLKHPKTSIQVLAAWTMSNVAAGPRHQVEQLLCNLLPILVDLLRNAELKVQKEVVCTVINIATGASQDQLTLLAHSGILEPMLSLLSAPDLEVVIIVLDIISYLLQHIDNLQEKKRLYFQIEKFGGFEKIECLQHHHNISISNSALDIIEKYFCEDGDGDSLPGPGLRV

Target ORF information:

RefSeq Version	XM_017320944.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus karyopherin alpha 7 (importin alpha 8) (Kpna7), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017320944.1

ORF Insert Sequence:

ATGGCTACCT CAAAGGCTCC CAAAGAGAGG CTGAAGAACT ATAAGTACCG AGGCAAAGAA 
ATGTCATTGC CACGACAACA GAGGATTGCT TCCAGTCTAC AACTCCGGAA GACCAGGAAA 
GATGAGCAGG TGCTAAAGAG AAGAAATATC GATCTGTTCT CCAGTGACAT GGTTTCTCAA 
GCACTAGTCA AAGAGGTCAA CTTCACTCTG GACGACATCA TCCAAGCGGT GAATAGTTCA 
GATCCAATCC TGCATTTTCG GGCTACCCGG GCTGCCAGGG AAATGATCTC GCAGGAAAAT 
ACCCCTCCTC TCAATTTGAT TATTGAGGCC GGGCTCATTC CCAAGCTGGT GGACTTCCTG 
AAGGCGACAC CTCACCCCAA GCTGCAGTTC GAGGCCGCAT GGGTGCTCAC CAACATTGCC 
TCAGGAACTT CAGAGCAGAC CCGAGCTGTT GTGAAAGAGG GTGCCATTCA GCCCCTGATT 
GAACTCCTCT GTTCCCCACA CCTGACAGTG TCTGAGCAGG CAGTGTGGGC CCTTGGGAAT 
ATCGCTGGAG ACTGTGCAGA ATTCAGAGAC TGTGTCATCT CCAATAATGC CATCCCACAC 
CTGATCAACC TTATTTCAAA AGGCATACCA ATCACATTTC TTCGGAACAT CTCATGGACT 
TTGTCCAACT TATGCCGAAA CAAAGATCCA TATCCCAGTG AGAGCGCCGT GCGGCAGATG 
CTACCTCCCC TCTGTCAACT CCTGCTGCAT CGTGATAATG AGATCCTCGC AGATACCTGC 
TGGGCCCTGT CCTACCTGAC CAAGGGTGGC AAAGAGTATA TCCATCATGT GGTGACCACT 
GGCATCCTGC CCAGGCTTGT AGAGCTTATG ACCAGCTCGG AACTCAGCAT CTCGATACCT 
TGTCTCCACA CTATAGGCAA CATTGTGGCA GGAACAGATG AACAGACCCA GATGGCTATC 
GATGCTGGCA TGCTGAAGGT GTTGGGCCAG GTCCTGAAGC ACCCGAAGAC CTCCATCCAG 
GTGCTGGCTG CCTGGACCAT GAGCAACGTG GCCGCTGGGC CCAGACACCA AGTGGAGCAG 
CTTTTGTGTA ACTTGCTGCC TATTTTGGTA GACCTACTAA GGAATGCAGA ATTAAAAGTC 
CAGAAGGAGG TTGTGTGCAC TGTGATTAAC ATTGCAACAG GAGCCTCTCA GGACCAGCTG 
ACTCTGCTTG CCCACTCGGG AATCTTGGAG CCAATGCTGA GTCTGCTCTC CGCCCCAGAC 
TTGGAGGTGG TCATCATCGT CCTAGACATC ATTTCTTATC TCCTCCAGCA TATAGACAAT 
CTACAAGAGA AGAAAAGGCT GTATTTTCAG ATAGAAAAAT TTGGTGGCTT TGAAAAAATT 
GAGTGTTTAC AGCACCACCA CAACATTTCC ATCAGCAATA GCGCCCTGGA CATCATCGAG 
AAATACTTCT GTGAGGATGG AGATGGTGAC AGTTTGCCCG GGCCTGGGCT GAGAGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

H7N9 Influenza A Virus Exhibits Importin-?7-Mediated Replication in the Mammalian Respiratory Tract.
The American journal of pathology187(4)831-840(2017 Apr)
Bertram S,Thiele S,Dreier C,Resa-Infante P,Preu? A,van Riel D,Mok CKP,Schwalm F,Peiris JSM,Klenk HD,Gabriel G

Changing expression and subcellular distribution of karyopherins during murine oogenesis.
Reproduction (Cambridge, England)150(6)485-96(2015 Dec)
Mihalas BP,Western PS,Loveland KL,McLaughlin EA,Holt JE

Importin ?7 is essential for zygotic genome activation and early mouse development.
PloS one6(3)e18310(2011 Mar)
Rother F,Shmidt T,Popova E,Krivokharchenko A,H?gel S,Vilianovich L,Ridders M,Tenner K,Alenina N,K?hler M,Hartmann E,Bader M

Novel importin-alpha family member Kpna7 is required for normal fertility and fecundity in the mouse.
The Journal of biological chemistry285(43)33113-22(2010 Oct)
Hu J,Wang F,Yuan Y,Zhu X,Wang Y,Zhang Y,Kou Z,Wang S,Gao S

Karyopherin alpha7 (KPNA7), a divergent member of the importin alpha family of nuclear import receptors.
BMC cell biology1163(2010 Aug)
Kelley JB,Talley AM,Spencer A,Gioeli D,Paschal BM

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Kpna7 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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見積依頼

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電話

FAX

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