Reg3d cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Reg3d
Entrez Gene ID	30053
Full Name	regenerating islet-derived 3 delta
Synonyms	INGAP,Ingaprp
General protein information	Preferred Names regenerating islet-derived 3 delta Names regenerating islet-derived 3 delta Reg III delta islet neogenesis associated protein-related protein
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6\|6 C3

mRNA and Protein(s)

mRNA	Protein	Name
NM_013893.2	NP_038921.2	regenerating islet-derived 3 delta isoform 1 precursor
NM_001161741.1	NP_001155213.1	regenerating islet-derived 3 delta isoform 2 precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	LOC100361595	XP_003749829.1
Mus musculus (house mouse)	Reg3d	NP_038921.2

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

A gene expression resource generated by genome-wide lacZ profiling in the mouse.
Tuck E, Estabel J, Oellrich A, Maguire AK, Adissu HA, Souter L, Siragher E, Lillistone C, Green AL, Wardle-Jones H, Carragher DM, Karp NA, Smedley D, Adams NC, , Bussell JN, Adams DJ, Ram?rez-Solis R, Steel KP, Galli A, White JK
Disease models & mechanisms8(11)1467-78(2015 Nov)

Targeted expression of islet neogenesis associated protein to beta cells enhances glucose tolerance and confers resistance to streptozotocin-induced hyperglycemia.
Chang TJ, Weaver JR, Bowman A, Leone K, Raab R, Vinik AI, Pittenger GL, Taylor-Fishwick DA
Molecular and cellular endocrinology335(2)104-9(2011 Mar)

Pancreatic islet immunoreactivity to the Reg protein INGAP.
Taylor-Fishwick DA, Bowman A, Korngiebel-Rosique M, Vinik AI
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society56(2)183-91(2008 Feb)

The Reg family member INGAP is a marker of endocrine patterning in the embryonic pancreas.
Hamblet NS, Shi W, Vinik AI, Taylor-Fishwick DA
Pancreas36(1)1-9(2008 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Immunoreactivity to INGAP localized to the pancreatic endocrine cells in mouse. INGAP and/or related group 3 Reg proteins have a conserved expression in the pancreatic islet.
Title: Pancreatic islet immunoreactivity to the Reg protein INGAP.

The following Reg3d gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Reg3d cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu08227	NM_001161741.1 Latest version!	Mus musculus regenerating islet-derived 3 delta (Reg3d), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OMu10127	NM_013893.2 Latest version!	Mus musculus regenerating islet-derived 3 delta (Reg3d), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Reg3d ( NM_001161741.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001155213.1 Mus musculus regenerating islet-derived 3 delta (Reg3d), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu08227
Clone ID Related Accession (Same CDS sequence)	NM_001161741.1
Accession Version	NM_001161741.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 390bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-28
Organism	Mus musculus(house mouse)
Product	regenerating islet-derived 3 delta isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AI594831.1, BM055959.1 and AB035204.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. ##Evidence-Data-START## CDS exon combination :: BM055973.1, BM055959.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMN00849377 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGTCTC ACAAGACCCT TCATAGCATG TCCTGGATGC TACTGTGTTG CCTGATGTCC 
CTTTCTTGGG TACAAGGTGA ACAATCCCAG AAAAAACTGT CTTCTCCACG CATCAGCTGT 
CCCCAAGAAG CCCAAGCTTA TGGCTCCTAT TGCTATTTAC TGATTCTGGA ACCACAGACC 
TGGGCTAATG CAGAGGGGAG TTTGCCCAAT GAAAATGGAT GGAAGTGGAG CAGCTCTGAC 
CCTCTGACCT TCTATAACTG GGAGATACCA CCCTCCATGT CTGCACACCA CGGCTACTGT 
GCAGCTTTGT CTCAGGCCTC AGGTTATCAG AAGTGGAGAG ATTATTATTG TGACACAATA 
TTTCCCTATG TCTGCAAATT CAAGGGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001155213.1
CDS	58..447
Translation	MVSHKTLHSMSWMLLCCLMSLSWVQGEQSQKKLSSPRISCPQEAQAYGSYCYLLILEPQTWANAEGSLPNENGWKWSSSDPLTFYNWEIPPSMSAHHGYCAALSQASGYQKWRDYYCDTIFPYVCKFKG

Target ORF information:

RefSeq Version	NM_001161741.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus regenerating islet-derived 3 delta (Reg3d), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001161741.1

ORF Insert Sequence:

ATGGTGTCTC ACAAGACCCT TCATAGCATG TCCTGGATGC TACTGTGTTG CCTGATGTCC 
CTTTCTTGGG TACAAGGTGA ACAATCCCAG AAAAAACTGT CTTCTCCACG CATCAGCTGT 
CCCCAAGAAG CCCAAGCTTA TGGCTCCTAT TGCTATTTAC TGATTCTGGA ACCACAGACC 
TGGGCTAATG CAGAGGGGAG TTTGCCCAAT GAAAATGGAT GGAAGTGGAG CAGCTCTGAC 
CCTCTGACCT TCTATAACTG GGAGATACCA CCCTCCATGT CTGCACACCA CGGCTACTGT 
GCAGCTTTGT CTCAGGCCTC AGGTTATCAG AAGTGGAGAG ATTATTATTG TGACACAATA 
TTTCCCTATG TCTGCAAATT CAAGGGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Reg3d ( NM_013893.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_038921.2 Mus musculus regenerating islet-derived 3 delta (Reg3d), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu10127
Clone ID Related Accession (Same CDS sequence)	NM_013893.2
Accession Version	NM_013893.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-28
Organism	Mus musculus(house mouse)
Product	regenerating islet-derived 3 delta isoform 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AI594831.1 and AB035204.1. On Jun 13, 2009 this sequence version replaced NM_013893.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: AB028625.1, AK019033.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849377, SAMN00849378 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGTCTC ACAAGACCCT TCATAGCATG TCCTGGATGC TACTGTGTTG CCTGATGTCC 
CTTTCTTGGG TACAAGGTGA ACAATCCCAG AAAAAACTGT CTTCTCCACG CATCAGCTGT 
CCCCAAGAAG CCCAAGCTTA TGGCTCCTAT TGCTATTTAC TGATTCTGGA ACCACAGACC 
TGGGCTAATG CAGAGATCCA CTGCCAGAAG CATTTCTCAG GACACCTGGC ATTTCTGCTC 
ACTTATGGTG AAATTATCTT TGTGTCCTCT CTGGTGAAAA ACAGTTTGAC CACATTCCCA 
TACATCTGGA TTGGACTCCA TGATCTGTCA CTTGGGAGTT TGCCCAATGA AAATGGATGG 
AAGTGGAGCA GCTCTGACCC TCTGACCTTC TATAACTGGG AGATACCACC CTCCATGTCT 
GCACACCACG GCTACTGTGC AGCTTTGTCT CAGGCCTCAG GTTATCAGAA GTGGAGAGAT 
TATTATTGTG ACACAATATT TCCCTATGTC TGCAAATTCA AGGGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_038921.2
CDS	58..585
Translation	MVSHKTLHSMSWMLLCCLMSLSWVQGEQSQKKLSSPRISCPQEAQAYGSYCYLLILEPQTWANAEIHCQKHFSGHLAFLLTYGEIIFVSSLVKNSLTTFPYIWIGLHDLSLGSLPNENGWKWSSSDPLTFYNWEIPPSMSAHHGYCAALSQASGYQKWRDYYCDTIFPYVCKFKG

Target ORF information:

RefSeq Version	NM_013893.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus regenerating islet-derived 3 delta (Reg3d), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013893.2

ORF Insert Sequence:

ATGGTGTCTC ACAAGACCCT TCATAGCATG TCCTGGATGC TACTGTGTTG CCTGATGTCC 
CTTTCTTGGG TACAAGGTGA ACAATCCCAG AAAAAACTGT CTTCTCCACG CATCAGCTGT 
CCCCAAGAAG CCCAAGCTTA TGGCTCCTAT TGCTATTTAC TGATTCTGGA ACCACAGACC 
TGGGCTAATG CAGAGATCCA CTGCCAGAAG CATTTCTCAG GACACCTGGC ATTTCTGCTC 
ACTTATGGTG AAATTATCTT TGTGTCCTCT CTGGTGAAAA ACAGTTTGAC CACATTCCCA 
TACATCTGGA TTGGACTCCA TGATCTGTCA CTTGGGAGTT TGCCCAATGA AAATGGATGG 
AAGTGGAGCA GCTCTGACCC TCTGACCTTC TATAACTGGG AGATACCACC CTCCATGTCT 
GCACACCACG GCTACTGTGC AGCTTTGTCT CAGGCCTCAG GTTATCAGAA GTGGAGAGAT 
TATTATTGTG ACACAATATT TCCCTATGTC TGCAAATTCA AGGGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

A gene expression resource generated by genome-wide lacZ profiling in the mouse.
Disease models & mechanisms8(11)1467-78(2015 Nov)
Tuck E,Estabel J,Oellrich A,Maguire AK,Adissu HA,Souter L,Siragher E,Lillistone C,Green AL,Wardle-Jones H,Carragher DM,Karp NA,Smedley D,Adams NC,,Bussell JN,Adams DJ,Ram?rez-Solis R,Steel KP,Galli A,White JK

Targeted expression of islet neogenesis associated protein to beta cells enhances glucose tolerance and confers resistance to streptozotocin-induced hyperglycemia.
Molecular and cellular endocrinology335(2)104-9(2011 Mar)
Chang TJ,Weaver JR,Bowman A,Leone K,Raab R,Vinik AI,Pittenger GL,Taylor-Fishwick DA

Pancreatic islet immunoreactivity to the Reg protein INGAP.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society56(2)183-91(2008 Feb)
Taylor-Fishwick DA,Bowman A,Korngiebel-Rosique M,Vinik AI

The Reg family member INGAP is a marker of endocrine patterning in the embryonic pancreas.
Pancreas36(1)1-9(2008 Jan)
Hamblet NS,Shi W,Vinik AI,Taylor-Fishwick DA