Cops3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cops3
Entrez Gene ID	26572
Full Name	COP9 signalosome subunit 3
Synonyms	Csn3,Sgn3
General protein information	Preferred Names COP9 signalosome subunit 3 Names COP9 signalosome complex subunit 3 COP9 (constitutive photomorphogenic) homolog, subunit 3 COP9 (constitutive photomorphogenic), subunit 3 COP9 complex S3 JAB1-containing signalosome subunit 3 signalosome subunit 3
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 11 Map Location: 11\|11 B1.3

mRNA and Protein(s)

mRNA	Protein	Name
XM_006533383.3	XP_006533446.1	COP9 signalosome complex subunit 3 isoform X1
XM_030246025.1	XP_030101885.1	COP9 signalosome complex subunit 3 isoform X1
XM_006533383.4	XP_006533446.1	COP9 signalosome complex subunit 3 isoform X2
XM_030246026.1	XP_030101886.1	COP9 signalosome complex subunit 3 isoform X1
XM_030246027.1	XP_030101887.1	COP9 signalosome complex subunit 3 isoform X2
NM_011991.1	NP_036121.1	COP9 signalosome complex subunit 3

Pathways from BioSystems

Homologies

Drosophila melanogaster (fruit fly)	CSN3	NP_524190.2
Pan troglodytes (chimpanzee)	COPS3	XP_001160602.1
Bos taurus (cattle)	COPS3	NP_001092374.1
Mus musculus (house mouse)	Cops3	NP_036121.1
Homo sapiens (human)	COPS3	NP_003644.2
Canis lupus familiaris (dog)	COPS3	XP_864801.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006445	XP_316484.4
Arabidopsis thaliana (thale cress)	COP13	NP_568296.1
Danio rerio (zebrafish)	cops3	NP_955979.1
Oryza sativa (rice)	Os08g0119000	NP_001060870.1
	COPS3	XP_001089733.2
Rattus norvegicus (Norway rat)	Cops3	NP_001004200.1
Gallus gallus (chicken)	COPS3	NP_001006163.1
Xenopus tropicalis (tropical clawed frog)	cops3	NP_001017238.1

Gene Ontology
Bibliography

Related articles in PubMed

Function of COP9 signalosome in regulation of mouse oocytes meiosis by regulating MPF activity and securing degradation.
Kim E, Yoon SJ, Kim EY, Kim Y, Lee HS, Kim KH, Lee KA
PloS one6(10)e25870(2011)

Phenotypic consequences of copy number variation: insights from Smith-Magenis and Potocki-Lupski syndrome mouse models.
Ricard G, Molina J, Chrast J, Gu W, Gheldof N, Pradervand S, Sch?tz F, Young JI, Lupski JR, Reymond A, Walz K
PLoS biology8(11)e1000543(2010 Nov)

Penetrance of craniofacial anomalies in mouse models of Smith-Magenis syndrome is modified by genomic sequence surrounding Rai1: not all null alleles are alike.
Yan J, Bi W, Lupski JR
American journal of human genetics80(3)518-25(2007 Mar)

COP9 signalosome subunit 3 is essential for maintenance of cell proliferation in the mouse embryonic epiblast.
Yan J, Walz K, Nakamura H, Carattini-Rivera S, Zhao Q, Vogel H, Wei N, Justice MJ, Bradley A, Lupski JR
Molecular and cellular biology23(19)6798-808(2003 Oct)

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic acids research31(1)278-81(2003 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

CSN3 and CSN5 are involved in oocyte meiosis by regulating degradation of Cyclin B1 and Securin via APC/C.
Title: Function of COP9 signalosome in regulation of mouse oocytes meiosis by regulating MPF activity and securing degradation.

Cops3 encodes the third subunit of the COP9 signalosome, which controls a wide vasriety of molecules of different functions.
Title: COP9 signalosome subunit 3 is essential for maintenance of cell proliferation in the mouse embryonic epiblast.

The following Cops3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cops3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu09285	NM_011991.1 Latest version!	Mus musculus COP9 signalosome subunit 3 (Cops3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
OMu46340	XM_030246027.1 Latest version!	Mus musculus COP9 signalosome subunit 3 (Cops3), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu46340	XM_006533383.4 Latest version!	Mus musculus COP9 signalosome subunit 3 (Cops3), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu85794	XM_030246026.1 Latest version!	Mus musculus COP9 signalosome subunit 3 (Cops3), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OMu85794	XM_030246025.1 Latest version!	Mus musculus COP9 signalosome subunit 3 (Cops3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OMu46340	XM_006533383.3	Mus musculus COP9 signalosome subunit 3 (Cops3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cops3 ( XM_006533383.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006533446.1 Mus musculus COP9 signalosome subunit 3 (Cops3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu46340
Clone ID Related Accession (Same CDS sequence)	XM_006533383.3 , XM_006533383.4 , XM_030246027.1
Accession Version	XM_006533383.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 882bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	COP9 signalosome complex subunit 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006533383.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGATGA ATACCAACCA ACTGACCTCA GTACATGCCG ATCTCTGCCA GCTTTGTTTA 
CTAGCGAAGT GCTTTAAACC TGCCCTTCCA TATCTTGATG TGGATATGAT GGATATCTGT 
AAAGAGAATG GAGCCTATGA TGCAAAACAC TTTCTGTGCT ACTACTATTA TGGAGGAATG 
ATCTATACGG GGCTGAAGAA CTTTGAAAGA GCGCTGTACT TTTATGAGCA GGCTATAACT 
ACTCCTGCCA TGGCCGTCAG CCATATCATG TTGGAATCAT ATAAAAAGTA TATTCTAGTG 
TCTTTGATAT TACTTGGCAA AGTACAACAG CTGCCTAAAT ACACCTCTCA AATAGTGGGT 
AGATTTATTA AGCCTCTCAG CAATGCTTAC CATGAGTTAG CACAAGTTTA TTCAACCAAC 
AACCCGTCTG AGCTGCGGAA CCTGGTGAGC AAGCACAGCG AGACCTTCAC TCGAGACAAC 
AACATGGGCC TGGTGAAGCA GTGCCTGTCG TCTCTTTATA AGAAGAACAT TCAGAGGCTG 
ACAAAGACTT TTTTAACACT ATCATTACAA GATATGGCAA GCCGTGTACA GTTATCTGGA 
CCACAGGAGG CAGAAAAATA TGTTCTACAC ATGATAGAAG ATGGAGAAAT TTTTGCAAGT 
ATTAACCAGA AGGATGGAAT GGTCAGTTTC CATGATAACC CTGAGAAGTA TAATAACCCA 
GCCATGCTTC ATAACATCGA CCAAGAGATG CTAAAATGCA TAGAGCTGGA TGAGCGACTG 
AAGGCTATGG ACCAGGAGAT CACGGTGAAC CCCCAGTTTG TTCAAAAGAG CATGGGCTCA 
CAAGAAGATG ACTCAGGAAA CAAGCCCTCC AGCTACTCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006533446.1
CDS	567..1448
Translation	MQMNTNQLTSVHADLCQLCLLAKCFKPALPYLDVDMMDICKENGAYDAKHFLCYYYYGGMIYTGLKNFERALYFYEQAITTPAMAVSHIMLESYKKYILVSLILLGKVQQLPKYTSQIVGRFIKPLSNAYHELAQVYSTNNPSELRNLVSKHSETFTRDNNMGLVKQCLSSLYKKNIQRLTKTFLTLSLQDMASRVQLSGPQEAEKYVLHMIEDGEIFASINQKDGMVSFHDNPEKYNNPAMLHNIDQEMLKCIELDERLKAMDQEITVNPQFVQKSMGSQEDDSGNKPSSYS

Target ORF information:

RefSeq Version	XM_006533383.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus COP9 signalosome subunit 3 (Cops3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006533383.3

ORF Insert Sequence:

ATGCAGATGA ATACCAACCA ACTGACCTCA GTACATGCCG ATCTCTGCCA GCTTTGTTTA 
CTAGCGAAGT GCTTTAAACC TGCCCTTCCA TATCTTGATG TGGATATGAT GGATATCTGT 
AAAGAGAATG GAGCCTATGA TGCAAAACAC TTTCTGTGCT ACTACTATTA TGGAGGAATG 
ATCTATACGG GGCTGAAGAA CTTTGAAAGA GCGCTGTACT TTTATGAGCA GGCTATAACT 
ACTCCTGCCA TGGCCGTCAG CCATATCATG TTGGAATCAT ATAAAAAGTA TATTCTAGTG 
TCTTTGATAT TACTTGGCAA AGTACAACAG CTGCCTAAAT ACACCTCTCA AATAGTGGGT 
AGATTTATTA AGCCTCTCAG CAATGCTTAC CATGAGTTAG CACAAGTTTA TTCAACCAAC 
AACCCGTCTG AGCTGCGGAA CCTGGTGAGC AAGCACAGCG AGACCTTCAC TCGAGACAAC 
AACATGGGCC TGGTGAAGCA GTGCCTGTCG TCTCTTTATA AGAAGAACAT TCAGAGGCTG 
ACAAAGACTT TTTTAACACT ATCATTACAA GATATGGCAA GCCGTGTACA GTTATCTGGA 
CCACAGGAGG CAGAAAAATA TGTTCTACAC ATGATAGAAG ATGGAGAAAT TTTTGCAAGT 
ATTAACCAGA AGGATGGAAT GGTCAGTTTC CATGATAACC CTGAGAAGTA TAATAACCCA 
GCCATGCTTC ATAACATCGA CCAAGAGATG CTAAAATGCA TAGAGCTGGA TGAGCGACTG 
AAGGCTATGG ACCAGGAGAT CACGGTGAAC CCCCAGTTTG TTCAAAAGAG CATGGGCTCA 
CAAGAAGATG ACTCAGGAAA CAAGCCCTCC AGCTACTCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cops3 ( NM_011991.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_036121.1 Mus musculus COP9 signalosome subunit 3 (Cops3), mRNA.

Price & Availability↑

CloneID	OMu09285
Clone ID Related Accession (Same CDS sequence)	NM_011991.1
Accession Version	NM_011991.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1272bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Mus musculus(house mouse)
Product	COP9 signalosome complex subunit 3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF071313.1. On Dec 7, 2005 this sequence version replaced XM_918025.1. ##Evidence-Data-START## Transcript exon combination :: AF071313.1, AK142318.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164135, SAMN01164137 [ECO:0000348] ##Evidence-Data-END##

ATGGCGTCTG CTCTGGAGCA GTTCGTGAAC AGTGTCCGAC AGCTCTCAGC TCAAGGGCAA 
ATGACTCAGC TTTGTGAACT CATCAACAAG AGTGGAGAAC TCCTTGCGAA GAACTTGTCC 
CATCTGGACA CTGTGCTTGG GGCTTTAGAT GTTCAAGAAC ACTCTTTGGG TGTCCTTGCT 
GTTCTGTTTG TGAAGTTCTC AATGCCCAGT GTTCCTGACT TCGAAACACT ATTCTCACAG 
GTTCAGCTTT TCATCAGTAC ATGTAATGGC GAGCACATTC GATATGCAAC AGATACGTTT 
GCTGGGCTTT GCCATCAGCT AACAAATGCA CTTGTGGAAA GAAAACAGCC CCTTCGAGGA 
ATTGGCATCC TTAAGCAAGC CATAGACAAG ATGCAGATGA ATACCAACCA ACTGACCTCA 
GTACATGCCG ATCTCTGCCA GCTTTGTTTA CTAGCGAAGT GCTTTAAACC TGCCCTTCCA 
TATCTTGATG TGGATATGAT GGATATCTGT AAAGAGAATG GAGCCTATGA TGCAAAACAC 
TTTCTGTGCT ACTACTATTA TGGAGGAATG ATCTATACGG GGCTGAAGAA CTTTGAAAGA 
GCGCTGTACT TTTATGAGCA GGCTATAACT ACTCCTGCCA TGGCCGTCAG CCATATCATG 
TTGGAATCAT ATAAAAAGTA TATTCTAGTG TCTTTGATAT TACTTGGCAA AGTACAACAG 
CTGCCTAAAT ACACCTCTCA AATAGTGGGT AGATTTATTA AGCCTCTCAG CAATGCTTAC 
CATGAGTTAG CACAAGTTTA TTCAACCAAC AACCCGTCTG AGCTGCGGAA CCTGGTGAGC 
AAGCACAGCG AGACCTTCAC TCGAGACAAC AACATGGGCC TGGTGAAGCA GTGCCTGTCG 
TCTCTTTATA AGAAGAACAT TCAGAGGCTG ACAAAGACTT TTTTAACACT ATCATTACAA 
GATATGGCAA GCCGTGTACA GTTATCTGGA CCACAGGAGG CAGAAAAATA TGTTCTACAC 
ATGATAGAAG ATGGAGAAAT TTTTGCAAGT ATTAACCAGA AGGATGGAAT GGTCAGTTTC 
CATGATAACC CTGAGAAGTA TAATAACCCA GCCATGCTTC ATAACATCGA CCAAGAGATG 
CTAAAATGCA TAGAGCTGGA TGAGCGACTG AAGGCTATGG ACCAGGAGAT CACGGTGAAC 
CCCCAGTTTG TTCAAAAGAG CATGGGCTCA CAAGAAGATG ACTCAGGAAA CAAGCCCTCC 
AGCTACTCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036121.1
CDS	44..1315
Translation	MASALEQFVNSVRQLSAQGQMTQLCELINKSGELLAKNLSHLDTVLGALDVQEHSLGVLAVLFVKFSMPSVPDFETLFSQVQLFISTCNGEHIRYATDTFAGLCHQLTNALVERKQPLRGIGILKQAIDKMQMNTNQLTSVHADLCQLCLLAKCFKPALPYLDVDMMDICKENGAYDAKHFLCYYYYGGMIYTGLKNFERALYFYEQAITTPAMAVSHIMLESYKKYILVSLILLGKVQQLPKYTSQIVGRFIKPLSNAYHELAQVYSTNNPSELRNLVSKHSETFTRDNNMGLVKQCLSSLYKKNIQRLTKTFLTLSLQDMASRVQLSGPQEAEKYVLHMIEDGEIFASINQKDGMVSFHDNPEKYNNPAMLHNIDQEMLKCIELDERLKAMDQEITVNPQFVQKSMGSQEDDSGNKPSSYS

Target ORF information:

RefSeq Version	NM_011991.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus COP9 signalosome subunit 3 (Cops3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011991.1

ORF Insert Sequence:

ATGGCGTCTG CTCTGGAGCA GTTCGTGAAC AGTGTCCGAC AGCTCTCAGC TCAAGGGCAA 
ATGACTCAGC TTTGTGAACT CATCAACAAG AGTGGAGAAC TCCTTGCGAA GAACTTGTCC 
CATCTGGACA CTGTGCTTGG GGCTTTAGAT GTTCAAGAAC ACTCTTTGGG TGTCCTTGCT 
GTTCTGTTTG TGAAGTTCTC AATGCCCAGT GTTCCTGACT TCGAAACACT ATTCTCACAG 
GTTCAGCTTT TCATCAGTAC ATGTAATGGC GAGCACATTC GATATGCAAC AGATACGTTT 
GCTGGGCTTT GCCATCAGCT AACAAATGCA CTTGTGGAAA GAAAACAGCC CCTTCGAGGA 
ATTGGCATCC TTAAGCAAGC CATAGACAAG ATGCAGATGA ATACCAACCA ACTGACCTCA 
GTACATGCCG ATCTCTGCCA GCTTTGTTTA CTAGCGAAGT GCTTTAAACC TGCCCTTCCA 
TATCTTGATG TGGATATGAT GGATATCTGT AAAGAGAATG GAGCCTATGA TGCAAAACAC 
TTTCTGTGCT ACTACTATTA TGGAGGAATG ATCTATACGG GGCTGAAGAA CTTTGAAAGA 
GCGCTGTACT TTTATGAGCA GGCTATAACT ACTCCTGCCA TGGCCGTCAG CCATATCATG 
TTGGAATCAT ATAAAAAGTA TATTCTAGTG TCTTTGATAT TACTTGGCAA AGTACAACAG 
CTGCCTAAAT ACACCTCTCA AATAGTGGGT AGATTTATTA AGCCTCTCAG CAATGCTTAC 
CATGAGTTAG CACAAGTTTA TTCAACCAAC AACCCGTCTG AGCTGCGGAA CCTGGTGAGC 
AAGCACAGCG AGACCTTCAC TCGAGACAAC AACATGGGCC TGGTGAAGCA GTGCCTGTCG 
TCTCTTTATA AGAAGAACAT TCAGAGGCTG ACAAAGACTT TTTTAACACT ATCATTACAA 
GATATGGCAA GCCGTGTACA GTTATCTGGA CCACAGGAGG CAGAAAAATA TGTTCTACAC 
ATGATAGAAG ATGGAGAAAT TTTTGCAAGT ATTAACCAGA AGGATGGAAT GGTCAGTTTC 
CATGATAACC CTGAGAAGTA TAATAACCCA GCCATGCTTC ATAACATCGA CCAAGAGATG 
CTAAAATGCA TAGAGCTGGA TGAGCGACTG AAGGCTATGG ACCAGGAGAT CACGGTGAAC 
CCCCAGTTTG TTCAAAAGAG CATGGGCTCA CAAGAAGATG ACTCAGGAAA CAAGCCCTCC 
AGCTACTCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cops3 ( XM_006533383.4 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006533446.1 Mus musculus COP9 signalosome subunit 3 (Cops3), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OMu46340
Clone ID Related Accession (Same CDS sequence)	XM_006533383.3 , XM_006533383.4 , XM_030246027.1
Accession Version	XM_006533383.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 882bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	COP9 signalosome complex subunit 3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006533383.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGATGA ATACCAACCA ACTGACCTCA GTACATGCCG ATCTCTGCCA GCTTTGTTTA 
CTAGCGAAGT GCTTTAAACC TGCCCTTCCA TATCTTGATG TGGATATGAT GGATATCTGT 
AAAGAGAATG GAGCCTATGA TGCAAAACAC TTTCTGTGCT ACTACTATTA TGGAGGAATG 
ATCTATACGG GGCTGAAGAA CTTTGAAAGA GCGCTGTACT TTTATGAGCA GGCTATAACT 
ACTCCTGCCA TGGCCGTCAG CCATATCATG TTGGAATCAT ATAAAAAGTA TATTCTAGTG 
TCTTTGATAT TACTTGGCAA AGTACAACAG CTGCCTAAAT ACACCTCTCA AATAGTGGGT 
AGATTTATTA AGCCTCTCAG CAATGCTTAC CATGAGTTAG CACAAGTTTA TTCAACCAAC 
AACCCGTCTG AGCTGCGGAA CCTGGTGAGC AAGCACAGCG AGACCTTCAC TCGAGACAAC 
AACATGGGCC TGGTGAAGCA GTGCCTGTCG TCTCTTTATA AGAAGAACAT TCAGAGGCTG 
ACAAAGACTT TTTTAACACT ATCATTACAA GATATGGCAA GCCGTGTACA GTTATCTGGA 
CCACAGGAGG CAGAAAAATA TGTTCTACAC ATGATAGAAG ATGGAGAAAT TTTTGCAAGT 
ATTAACCAGA AGGATGGAAT GGTCAGTTTC CATGATAACC CTGAGAAGTA TAATAACCCA 
GCCATGCTTC ATAACATCGA CCAAGAGATG CTAAAATGCA TAGAGCTGGA TGAGCGACTG 
AAGGCTATGG ACCAGGAGAT CACGGTGAAC CCCCAGTTTG TTCAAAAGAG CATGGGCTCA 
CAAGAAGATG ACTCAGGAAA CAAGCCCTCC AGCTACTCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006533446.1
CDS	550..1431
Translation	MQMNTNQLTSVHADLCQLCLLAKCFKPALPYLDVDMMDICKENGAYDAKHFLCYYYYGGMIYTGLKNFERALYFYEQAITTPAMAVSHIMLESYKKYILVSLILLGKVQQLPKYTSQIVGRFIKPLSNAYHELAQVYSTNNPSELRNLVSKHSETFTRDNNMGLVKQCLSSLYKKNIQRLTKTFLTLSLQDMASRVQLSGPQEAEKYVLHMIEDGEIFASINQKDGMVSFHDNPEKYNNPAMLHNIDQEMLKCIELDERLKAMDQEITVNPQFVQKSMGSQEDDSGNKPSSYS

Target ORF information:

RefSeq Version	XM_006533383.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus COP9 signalosome subunit 3 (Cops3), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006533383.4

ORF Insert Sequence:

ATGCAGATGA ATACCAACCA ACTGACCTCA GTACATGCCG ATCTCTGCCA GCTTTGTTTA 
CTAGCGAAGT GCTTTAAACC TGCCCTTCCA TATCTTGATG TGGATATGAT GGATATCTGT 
AAAGAGAATG GAGCCTATGA TGCAAAACAC TTTCTGTGCT ACTACTATTA TGGAGGAATG 
ATCTATACGG GGCTGAAGAA CTTTGAAAGA GCGCTGTACT TTTATGAGCA GGCTATAACT 
ACTCCTGCCA TGGCCGTCAG CCATATCATG TTGGAATCAT ATAAAAAGTA TATTCTAGTG 
TCTTTGATAT TACTTGGCAA AGTACAACAG CTGCCTAAAT ACACCTCTCA AATAGTGGGT 
AGATTTATTA AGCCTCTCAG CAATGCTTAC CATGAGTTAG CACAAGTTTA TTCAACCAAC 
AACCCGTCTG AGCTGCGGAA CCTGGTGAGC AAGCACAGCG AGACCTTCAC TCGAGACAAC 
AACATGGGCC TGGTGAAGCA GTGCCTGTCG TCTCTTTATA AGAAGAACAT TCAGAGGCTG 
ACAAAGACTT TTTTAACACT ATCATTACAA GATATGGCAA GCCGTGTACA GTTATCTGGA 
CCACAGGAGG CAGAAAAATA TGTTCTACAC ATGATAGAAG ATGGAGAAAT TTTTGCAAGT 
ATTAACCAGA AGGATGGAAT GGTCAGTTTC CATGATAACC CTGAGAAGTA TAATAACCCA 
GCCATGCTTC ATAACATCGA CCAAGAGATG CTAAAATGCA TAGAGCTGGA TGAGCGACTG 
AAGGCTATGG ACCAGGAGAT CACGGTGAAC CCCCAGTTTG TTCAAAAGAG CATGGGCTCA 
CAAGAAGATG ACTCAGGAAA CAAGCCCTCC AGCTACTCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cops3 ( XM_030246027.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030101887.1 Mus musculus COP9 signalosome subunit 3 (Cops3), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OMu46340
Clone ID Related Accession (Same CDS sequence)	XM_006533383.3 , XM_006533383.4 , XM_030246027.1
Accession Version	XM_030246027.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 882bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	COP9 signalosome complex subunit 3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGATGA ATACCAACCA ACTGACCTCA GTACATGCCG ATCTCTGCCA GCTTTGTTTA 
CTAGCGAAGT GCTTTAAACC TGCCCTTCCA TATCTTGATG TGGATATGAT GGATATCTGT 
AAAGAGAATG GAGCCTATGA TGCAAAACAC TTTCTGTGCT ACTACTATTA TGGAGGAATG 
ATCTATACGG GGCTGAAGAA CTTTGAAAGA GCGCTGTACT TTTATGAGCA GGCTATAACT 
ACTCCTGCCA TGGCCGTCAG CCATATCATG TTGGAATCAT ATAAAAAGTA TATTCTAGTG 
TCTTTGATAT TACTTGGCAA AGTACAACAG CTGCCTAAAT ACACCTCTCA AATAGTGGGT 
AGATTTATTA AGCCTCTCAG CAATGCTTAC CATGAGTTAG CACAAGTTTA TTCAACCAAC 
AACCCGTCTG AGCTGCGGAA CCTGGTGAGC AAGCACAGCG AGACCTTCAC TCGAGACAAC 
AACATGGGCC TGGTGAAGCA GTGCCTGTCG TCTCTTTATA AGAAGAACAT TCAGAGGCTG 
ACAAAGACTT TTTTAACACT ATCATTACAA GATATGGCAA GCCGTGTACA GTTATCTGGA 
CCACAGGAGG CAGAAAAATA TGTTCTACAC ATGATAGAAG ATGGAGAAAT TTTTGCAAGT 
ATTAACCAGA AGGATGGAAT GGTCAGTTTC CATGATAACC CTGAGAAGTA TAATAACCCA 
GCCATGCTTC ATAACATCGA CCAAGAGATG CTAAAATGCA TAGAGCTGGA TGAGCGACTG 
AAGGCTATGG ACCAGGAGAT CACGGTGAAC CCCCAGTTTG TTCAAAAGAG CATGGGCTCA 
CAAGAAGATG ACTCAGGAAA CAAGCCCTCC AGCTACTCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030101887.1
CDS	504..1385
Translation	MQMNTNQLTSVHADLCQLCLLAKCFKPALPYLDVDMMDICKENGAYDAKHFLCYYYYGGMIYTGLKNFERALYFYEQAITTPAMAVSHIMLESYKKYILVSLILLGKVQQLPKYTSQIVGRFIKPLSNAYHELAQVYSTNNPSELRNLVSKHSETFTRDNNMGLVKQCLSSLYKKNIQRLTKTFLTLSLQDMASRVQLSGPQEAEKYVLHMIEDGEIFASINQKDGMVSFHDNPEKYNNPAMLHNIDQEMLKCIELDERLKAMDQEITVNPQFVQKSMGSQEDDSGNKPSSYS

Target ORF information:

RefSeq Version	XM_030246027.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus COP9 signalosome subunit 3 (Cops3), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030246027.1

ORF Insert Sequence:

ATGCAGATGA ATACCAACCA ACTGACCTCA GTACATGCCG ATCTCTGCCA GCTTTGTTTA 
CTAGCGAAGT GCTTTAAACC TGCCCTTCCA TATCTTGATG TGGATATGAT GGATATCTGT 
AAAGAGAATG GAGCCTATGA TGCAAAACAC TTTCTGTGCT ACTACTATTA TGGAGGAATG 
ATCTATACGG GGCTGAAGAA CTTTGAAAGA GCGCTGTACT TTTATGAGCA GGCTATAACT 
ACTCCTGCCA TGGCCGTCAG CCATATCATG TTGGAATCAT ATAAAAAGTA TATTCTAGTG 
TCTTTGATAT TACTTGGCAA AGTACAACAG CTGCCTAAAT ACACCTCTCA AATAGTGGGT 
AGATTTATTA AGCCTCTCAG CAATGCTTAC CATGAGTTAG CACAAGTTTA TTCAACCAAC 
AACCCGTCTG AGCTGCGGAA CCTGGTGAGC AAGCACAGCG AGACCTTCAC TCGAGACAAC 
AACATGGGCC TGGTGAAGCA GTGCCTGTCG TCTCTTTATA AGAAGAACAT TCAGAGGCTG 
ACAAAGACTT TTTTAACACT ATCATTACAA GATATGGCAA GCCGTGTACA GTTATCTGGA 
CCACAGGAGG CAGAAAAATA TGTTCTACAC ATGATAGAAG ATGGAGAAAT TTTTGCAAGT 
ATTAACCAGA AGGATGGAAT GGTCAGTTTC CATGATAACC CTGAGAAGTA TAATAACCCA 
GCCATGCTTC ATAACATCGA CCAAGAGATG CTAAAATGCA TAGAGCTGGA TGAGCGACTG 
AAGGCTATGG ACCAGGAGAT CACGGTGAAC CCCCAGTTTG TTCAAAAGAG CATGGGCTCA 
CAAGAAGATG ACTCAGGAAA CAAGCCCTCC AGCTACTCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cops3 ( XM_030246025.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030101885.1 Mus musculus COP9 signalosome subunit 3 (Cops3), transcript variant X1, mRNA.

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CloneID	OMu85794
Clone ID Related Accession (Same CDS sequence)	XM_030246025.1 , XM_030246026.1
Accession Version	XM_030246025.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1212bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	COP9 signalosome complex subunit 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACTCAGC TTTGTGAACT CATCAACAAG AGTGGAGAAC TCCTTGCGAA GAACTTGTCC 
CATCTGGACA CTGTGCTTGG GGCTTTAGAT GTTCAAGAAC ACTCTTTGGG TGTCCTTGCT 
GTTCTGTTTG TGAAGTTCTC AATGCCCAGT GTTCCTGACT TCGAAACACT ATTCTCACAG 
GTTCAGCTTT TCATCAGTAC ATGTAATGGC GAGCACATTC GATATGCAAC AGATACGTTT 
GCTGGGCTTT GCCATCAGCT AACAAATGCA CTTGTGGAAA GAAAACAGCC CCTTCGAGGA 
ATTGGCATCC TTAAGCAAGC CATAGACAAG ATGCAGATGA ATACCAACCA ACTGACCTCA 
GTACATGCCG ATCTCTGCCA GCTTTGTTTA CTAGCGAAGT GCTTTAAACC TGCCCTTCCA 
TATCTTGATG TGGATATGAT GGATATCTGT AAAGAGAATG GAGCCTATGA TGCAAAACAC 
TTTCTGTGCT ACTACTATTA TGGAGGAATG ATCTATACGG GGCTGAAGAA CTTTGAAAGA 
GCGCTGTACT TTTATGAGCA GGCTATAACT ACTCCTGCCA TGGCCGTCAG CCATATCATG 
TTGGAATCAT ATAAAAAGTA TATTCTAGTG TCTTTGATAT TACTTGGCAA AGTACAACAG 
CTGCCTAAAT ACACCTCTCA AATAGTGGGT AGATTTATTA AGCCTCTCAG CAATGCTTAC 
CATGAGTTAG CACAAGTTTA TTCAACCAAC AACCCGTCTG AGCTGCGGAA CCTGGTGAGC 
AAGCACAGCG AGACCTTCAC TCGAGACAAC AACATGGGCC TGGTGAAGCA GTGCCTGTCG 
TCTCTTTATA AGAAGAACAT TCAGAGGCTG ACAAAGACTT TTTTAACACT ATCATTACAA 
GATATGGCAA GCCGTGTACA GTTATCTGGA CCACAGGAGG CAGAAAAATA TGTTCTACAC 
ATGATAGAAG ATGGAGAAAT TTTTGCAAGT ATTAACCAGA AGGATGGAAT GGTCAGTTTC 
CATGATAACC CTGAGAAGTA TAATAACCCA GCCATGCTTC ATAACATCGA CCAAGAGATG 
CTAAAATGCA TAGAGCTGGA TGAGCGACTG AAGGCTATGG ACCAGGAGAT CACGGTGAAC 
CCCCAGTTTG TTCAAAAGAG CATGGGCTCA CAAGAAGATG ACTCAGGAAA CAAGCCCTCC 
AGCTACTCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030101885.1
CDS	192..1403
Translation	MTQLCELINKSGELLAKNLSHLDTVLGALDVQEHSLGVLAVLFVKFSMPSVPDFETLFSQVQLFISTCNGEHIRYATDTFAGLCHQLTNALVERKQPLRGIGILKQAIDKMQMNTNQLTSVHADLCQLCLLAKCFKPALPYLDVDMMDICKENGAYDAKHFLCYYYYGGMIYTGLKNFERALYFYEQAITTPAMAVSHIMLESYKKYILVSLILLGKVQQLPKYTSQIVGRFIKPLSNAYHELAQVYSTNNPSELRNLVSKHSETFTRDNNMGLVKQCLSSLYKKNIQRLTKTFLTLSLQDMASRVQLSGPQEAEKYVLHMIEDGEIFASINQKDGMVSFHDNPEKYNNPAMLHNIDQEMLKCIELDERLKAMDQEITVNPQFVQKSMGSQEDDSGNKPSSYS

Target ORF information:

RefSeq Version	XM_030246025.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus COP9 signalosome subunit 3 (Cops3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030246025.1

ORF Insert Sequence:

ATGACTCAGC TTTGTGAACT CATCAACAAG AGTGGAGAAC TCCTTGCGAA GAACTTGTCC 
CATCTGGACA CTGTGCTTGG GGCTTTAGAT GTTCAAGAAC ACTCTTTGGG TGTCCTTGCT 
GTTCTGTTTG TGAAGTTCTC AATGCCCAGT GTTCCTGACT TCGAAACACT ATTCTCACAG 
GTTCAGCTTT TCATCAGTAC ATGTAATGGC GAGCACATTC GATATGCAAC AGATACGTTT 
GCTGGGCTTT GCCATCAGCT AACAAATGCA CTTGTGGAAA GAAAACAGCC CCTTCGAGGA 
ATTGGCATCC TTAAGCAAGC CATAGACAAG ATGCAGATGA ATACCAACCA ACTGACCTCA 
GTACATGCCG ATCTCTGCCA GCTTTGTTTA CTAGCGAAGT GCTTTAAACC TGCCCTTCCA 
TATCTTGATG TGGATATGAT GGATATCTGT AAAGAGAATG GAGCCTATGA TGCAAAACAC 
TTTCTGTGCT ACTACTATTA TGGAGGAATG ATCTATACGG GGCTGAAGAA CTTTGAAAGA 
GCGCTGTACT TTTATGAGCA GGCTATAACT ACTCCTGCCA TGGCCGTCAG CCATATCATG 
TTGGAATCAT ATAAAAAGTA TATTCTAGTG TCTTTGATAT TACTTGGCAA AGTACAACAG 
CTGCCTAAAT ACACCTCTCA AATAGTGGGT AGATTTATTA AGCCTCTCAG CAATGCTTAC 
CATGAGTTAG CACAAGTTTA TTCAACCAAC AACCCGTCTG AGCTGCGGAA CCTGGTGAGC 
AAGCACAGCG AGACCTTCAC TCGAGACAAC AACATGGGCC TGGTGAAGCA GTGCCTGTCG 
TCTCTTTATA AGAAGAACAT TCAGAGGCTG ACAAAGACTT TTTTAACACT ATCATTACAA 
GATATGGCAA GCCGTGTACA GTTATCTGGA CCACAGGAGG CAGAAAAATA TGTTCTACAC 
ATGATAGAAG ATGGAGAAAT TTTTGCAAGT ATTAACCAGA AGGATGGAAT GGTCAGTTTC 
CATGATAACC CTGAGAAGTA TAATAACCCA GCCATGCTTC ATAACATCGA CCAAGAGATG 
CTAAAATGCA TAGAGCTGGA TGAGCGACTG AAGGCTATGG ACCAGGAGAT CACGGTGAAC 
CCCCAGTTTG TTCAAAAGAG CATGGGCTCA CAAGAAGATG ACTCAGGAAA CAAGCCCTCC 
AGCTACTCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cops3 ( XM_030246026.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030101886.1 Mus musculus COP9 signalosome subunit 3 (Cops3), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OMu85794
Clone ID Related Accession (Same CDS sequence)	XM_030246025.1 , XM_030246026.1
Accession Version	XM_030246026.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1212bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	COP9 signalosome complex subunit 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000077.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACTCAGC TTTGTGAACT CATCAACAAG AGTGGAGAAC TCCTTGCGAA GAACTTGTCC 
CATCTGGACA CTGTGCTTGG GGCTTTAGAT GTTCAAGAAC ACTCTTTGGG TGTCCTTGCT 
GTTCTGTTTG TGAAGTTCTC AATGCCCAGT GTTCCTGACT TCGAAACACT ATTCTCACAG 
GTTCAGCTTT TCATCAGTAC ATGTAATGGC GAGCACATTC GATATGCAAC AGATACGTTT 
GCTGGGCTTT GCCATCAGCT AACAAATGCA CTTGTGGAAA GAAAACAGCC CCTTCGAGGA 
ATTGGCATCC TTAAGCAAGC CATAGACAAG ATGCAGATGA ATACCAACCA ACTGACCTCA 
GTACATGCCG ATCTCTGCCA GCTTTGTTTA CTAGCGAAGT GCTTTAAACC TGCCCTTCCA 
TATCTTGATG TGGATATGAT GGATATCTGT AAAGAGAATG GAGCCTATGA TGCAAAACAC 
TTTCTGTGCT ACTACTATTA TGGAGGAATG ATCTATACGG GGCTGAAGAA CTTTGAAAGA 
GCGCTGTACT TTTATGAGCA GGCTATAACT ACTCCTGCCA TGGCCGTCAG CCATATCATG 
TTGGAATCAT ATAAAAAGTA TATTCTAGTG TCTTTGATAT TACTTGGCAA AGTACAACAG 
CTGCCTAAAT ACACCTCTCA AATAGTGGGT AGATTTATTA AGCCTCTCAG CAATGCTTAC 
CATGAGTTAG CACAAGTTTA TTCAACCAAC AACCCGTCTG AGCTGCGGAA CCTGGTGAGC 
AAGCACAGCG AGACCTTCAC TCGAGACAAC AACATGGGCC TGGTGAAGCA GTGCCTGTCG 
TCTCTTTATA AGAAGAACAT TCAGAGGCTG ACAAAGACTT TTTTAACACT ATCATTACAA 
GATATGGCAA GCCGTGTACA GTTATCTGGA CCACAGGAGG CAGAAAAATA TGTTCTACAC 
ATGATAGAAG ATGGAGAAAT TTTTGCAAGT ATTAACCAGA AGGATGGAAT GGTCAGTTTC 
CATGATAACC CTGAGAAGTA TAATAACCCA GCCATGCTTC ATAACATCGA CCAAGAGATG 
CTAAAATGCA TAGAGCTGGA TGAGCGACTG AAGGCTATGG ACCAGGAGAT CACGGTGAAC 
CCCCAGTTTG TTCAAAAGAG CATGGGCTCA CAAGAAGATG ACTCAGGAAA CAAGCCCTCC 
AGCTACTCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030101886.1
CDS	495..1706
Translation	MTQLCELINKSGELLAKNLSHLDTVLGALDVQEHSLGVLAVLFVKFSMPSVPDFETLFSQVQLFISTCNGEHIRYATDTFAGLCHQLTNALVERKQPLRGIGILKQAIDKMQMNTNQLTSVHADLCQLCLLAKCFKPALPYLDVDMMDICKENGAYDAKHFLCYYYYGGMIYTGLKNFERALYFYEQAITTPAMAVSHIMLESYKKYILVSLILLGKVQQLPKYTSQIVGRFIKPLSNAYHELAQVYSTNNPSELRNLVSKHSETFTRDNNMGLVKQCLSSLYKKNIQRLTKTFLTLSLQDMASRVQLSGPQEAEKYVLHMIEDGEIFASINQKDGMVSFHDNPEKYNNPAMLHNIDQEMLKCIELDERLKAMDQEITVNPQFVQKSMGSQEDDSGNKPSSYS

Target ORF information:

RefSeq Version	XM_030246026.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus COP9 signalosome subunit 3 (Cops3), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030246026.1

ORF Insert Sequence:

ATGACTCAGC TTTGTGAACT CATCAACAAG AGTGGAGAAC TCCTTGCGAA GAACTTGTCC 
CATCTGGACA CTGTGCTTGG GGCTTTAGAT GTTCAAGAAC ACTCTTTGGG TGTCCTTGCT 
GTTCTGTTTG TGAAGTTCTC AATGCCCAGT GTTCCTGACT TCGAAACACT ATTCTCACAG 
GTTCAGCTTT TCATCAGTAC ATGTAATGGC GAGCACATTC GATATGCAAC AGATACGTTT 
GCTGGGCTTT GCCATCAGCT AACAAATGCA CTTGTGGAAA GAAAACAGCC CCTTCGAGGA 
ATTGGCATCC TTAAGCAAGC CATAGACAAG ATGCAGATGA ATACCAACCA ACTGACCTCA 
GTACATGCCG ATCTCTGCCA GCTTTGTTTA CTAGCGAAGT GCTTTAAACC TGCCCTTCCA 
TATCTTGATG TGGATATGAT GGATATCTGT AAAGAGAATG GAGCCTATGA TGCAAAACAC 
TTTCTGTGCT ACTACTATTA TGGAGGAATG ATCTATACGG GGCTGAAGAA CTTTGAAAGA 
GCGCTGTACT TTTATGAGCA GGCTATAACT ACTCCTGCCA TGGCCGTCAG CCATATCATG 
TTGGAATCAT ATAAAAAGTA TATTCTAGTG TCTTTGATAT TACTTGGCAA AGTACAACAG 
CTGCCTAAAT ACACCTCTCA AATAGTGGGT AGATTTATTA AGCCTCTCAG CAATGCTTAC 
CATGAGTTAG CACAAGTTTA TTCAACCAAC AACCCGTCTG AGCTGCGGAA CCTGGTGAGC 
AAGCACAGCG AGACCTTCAC TCGAGACAAC AACATGGGCC TGGTGAAGCA GTGCCTGTCG 
TCTCTTTATA AGAAGAACAT TCAGAGGCTG ACAAAGACTT TTTTAACACT ATCATTACAA 
GATATGGCAA GCCGTGTACA GTTATCTGGA CCACAGGAGG CAGAAAAATA TGTTCTACAC 
ATGATAGAAG ATGGAGAAAT TTTTGCAAGT ATTAACCAGA AGGATGGAAT GGTCAGTTTC 
CATGATAACC CTGAGAAGTA TAATAACCCA GCCATGCTTC ATAACATCGA CCAAGAGATG 
CTAAAATGCA TAGAGCTGGA TGAGCGACTG AAGGCTATGG ACCAGGAGAT CACGGTGAAC 
CCCCAGTTTG TTCAAAAGAG CATGGGCTCA CAAGAAGATG ACTCAGGAAA CAAGCCCTCC 
AGCTACTCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Function of COP9 signalosome in regulation of mouse oocytes meiosis by regulating MPF activity and securing degradation.
PloS one6(10)e25870(2011)
Kim E,Yoon SJ,Kim EY,Kim Y,Lee HS,Kim KH,Lee KA

Phenotypic consequences of copy number variation: insights from Smith-Magenis and Potocki-Lupski syndrome mouse models.
PLoS biology8(11)e1000543(2010 Nov)
Ricard G,Molina J,Chrast J,Gu W,Gheldof N,Pradervand S,Sch?tz F,Young JI,Lupski JR,Reymond A,Walz K

Penetrance of craniofacial anomalies in mouse models of Smith-Magenis syndrome is modified by genomic sequence surrounding Rai1: not all null alleles are alike.
American journal of human genetics80(3)518-25(2007 Mar)
Yan J,Bi W,Lupski JR

COP9 signalosome subunit 3 is essential for maintenance of cell proliferation in the mouse embryonic epiblast.
Molecular and cellular biology23(19)6798-808(2003 Oct)
Yan J,Walz K,Nakamura H,Carattini-Rivera S,Zhao Q,Vogel H,Wei N,Justice MJ,Bradley A,Lupski JR

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Nucleic acids research31(1)278-81(2003 Jan)
Stryke D,Kawamoto M,Huang CC,Johns SJ,King LA,Harper CA,Meng EC,Lee RE,Yee A,L'Italien L,Chuang PT,Young SG,Skarnes WC,Babbitt PC,Ferrin TE

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Cops3 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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見積依頼

Eメール

電話

FAX

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