Mab21l2 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mab21l2
Entrez Gene ID	23937
Full Name	mab-21-like 2 (C. elegans)
General protein information	Preferred Names mab-21-like 2 (C. elegans) Names protein mab-21-like 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 3 Map Location: 3\|3 F1

mRNA and Protein(s)

mRNA	Protein	Name
NM_011839.3	NP_035969.2	protein mab-21-like 2
NM_011839.4	NP_035969.2	protein mab-21-like 2

Pathways from BioSystems

Homologies

	MAB21L2	XP_001082398.1
Xenopus tropicalis (tropical clawed frog)	mab21l2	NP_001096455.1
Anopheles gambiae (African malaria mosquito)	MB21L_ANOGA	XP_309230.3
Homo sapiens (human)	MAB21L2	NP_006430.1
Pan troglodytes (chimpanzee)	MAB21L2	XP_001151747.1
Bos taurus (cattle)	MAB21L2	XP_002694365.1
Mus musculus (house mouse)	Mab21l2	NP_035969.2
Canis lupus familiaris (dog)	MAB21L2	XP_867530.2
Rattus norvegicus (Norway rat)	Mab21l2	NP_001102861.1
Danio rerio (zebrafish)	mab21l2	NP_694507.1
Drosophila melanogaster (fruit fly)	CG4766	NP_572287.1

Gene Ontology
Bibliography

Related articles in PubMed

Monoallelic and biallelic mutations in MAB21L2 cause a spectrum of major eye malformations.
Rainger J, Pehlivan D, Johansson S, Bengani H, Sanchez-Pulido L, Williamson KA, Ture M, Barker H, Rosendahl K, Spranger J, Horn D, Meynert A, Floyd JA, Prescott T, Anderson CA, Rainger JK, Karaca E, Gonzaga-Jauregui C, Jhangiani S, Muzny DM, Seawright A, Soares DC, Kharbanda M, Murday V, Finch A, , , Gibbs RA, van Heyningen V, Taylor MS, Yakut T, Knappskog PM, Hurles ME, Ponting CP, Lupski JR, Houge G, FitzPatrick DR
American journal of human genetics94(6)915-23(2014 Jun)

Genetic analysis of the role of Alx4 in the coordination of lower body and external genitalia formation.
Matsumaru D, Haraguchi R, Moon AM, Satoh Y, Nakagata N, Yamamura K, Takahashi N, Kitazawa S, Yamada G
European journal of human genetics : EJHG22(3)350-7(2014 Mar)

Differential expression of Meis2, Mab21l2 and Tbx3 during limb development associated with diversification of limb morphology in mammals.
Dai M, Wang Y, Fang L, Irwin DM, Zhu T, Zhang J, Zhang S, Wang Z
PloS one9(8)e106100(2014)

The septum transversum mesenchyme induces gall bladder development.
Saito Y, Kojima T, Takahashi N
Biology open2(8)779-88(2013 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In mouse embryos, Mab21l2 showed strong expression in the developing eye, pharyngeal arches, and limb bud.
Title: Monoallelic and biallelic mutations in MAB21L2 cause a spectrum of major eye malformations.

Mab21l2 plays a crucial role in both heart and liver development through septum transversum mesenchyme (STM) formation.
Title: Mab21l2 is essential for embryonic heart and liver development.

Results reveal that Mab21l2 plays crucial roles in retina and in ventral body wall formation.
Title: Requirement for Mab21l2 during development of murine retina and ventral body wall.

required in developing embryos for embryonic turning, formation of the notochord, neural tube, and other organ tissues
Title: Depletion of Mab21l1 and Mab21l2 messages in mouse embryo arrests axial turning, and impairs notochord and neural tube differentiation.

The following Mab21l2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mab21l2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu58268	NM_011839.4 Latest version!	Mus musculus mab-21-like 2 (Mab21l2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OMu58268	NM_011839.3	Mus musculus mab-21-like 2 (C. elegans) (Mab21l2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mab21l2 ( NM_011839.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_035969.2 Mus musculus mab-21-like 2 (C. elegans) (Mab21l2), mRNA.

Price & Availability↑

CloneID	OMu58268
Clone ID Related Accession (Same CDS sequence)	NM_011839.3 , NM_011839.4
Accession Version	NM_011839.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1080bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-28
Organism	Mus musculus(house mouse)
Product	protein mab-21-like 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK053645.1. On Apr 5, 2007 this sequence version replaced NM_011839.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: AK053645.1 [ECO:0000345] ##Evidence-Data-END##

ATGATCGCCG CTCAGGCCAA GCTGGTTTAC CAGCTCAATA AATACTACAC CGAGCGCTGC 
CAGGCGCGCA AGGCTGCGAT CGCCAAGACC ATCCGAGAAG TCTGCAAGGT AGTGTCGGAT 
GTGCTAAAGG AAGTGGAGGT GCAAGAGCCC CGCTTCATCA GCTCTCTGAG TGAGATTGAC 
GCCCGCTACG AGGGGCTGGA GGTAATCTCG CCCACCGAGT TCGAGGTGGT ACTCTACCTC 
AACCAGATGG GAGTCTTCAA CTTCGTGGAC GACGGATCTC TGCCCGGCTG TGCCGTGCTC 
AAACTAAGCG ATGGGCGGAA GCGGAGCATG TCTCTTTGGG TCGAGTTCAT CACAGCGTCT 
GGCTACCTTT CTGCGCGCAA GATCCGCTCG CGTTTCCAGA CACTAGTAGC CCAGGCGGTG 
GACAAGTGCA GCTACCGGGA CGTGGTCAAG ATGATCGCCG ACACTAGTGA GGTCAAGTTG 
CGCATCAGGG AGCGCTACGT GGTGCAAATC ACCCCAGCGT TCAAGTGCAC CGGGATCTGG 
CCTCGCAGCG CGGCACAGTG GCCTATGCCC CACATCCCCT GGCCCGGCCC CAATCGGGTG 
GCGGAGGTCA AGGCCGAAGG GTTCAACTTG CTCTCCAAGG AGTGCTACTC GCTGACTGGC 
AAGCAGAGCT CCGCAGAAAG CGACGCCTGG GTGCTGCAGT TCGGTGAGGC GGAGAACCGC 
TTGCTGATGG GCGGCTGTAG AAACAAGTGC CTCTCGGTGC TGAAGACGCT GCGGGACCGC 
CACCTGGAGC TGCCTGGCCA GCCGCTCAAT AACTACCACA TGAAGACGCT GCTGCTGTAC 
GAGTGCGAGA AACACCCGAG GGAAACGGAC TGGGACGAGG CTTGCTTGGG CGACCGTCTG 
AACGGCATCC TGCTACAGCT CATCTCCTGC CTGCAGTGCC GCCGCTGCCC TCACTACTTT 
TTGCCCAACC TCGACCTCTT CCAGGGTAAG CCCCACTCGG CCCTGGAGAG CGCTGCCAAG 
CAGACCTGGA GATTGGCCAG GGAAATCCTC ACCAATCCCA AAAGCTTGGA CAAACTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_035969.2
CDS	593..1672
Translation	MIAAQAKLVYQLNKYYTERCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLSEIDARYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMIADTSEVKLRIRERYVVQITPAFKCTGIWPRSAAQWPMPHIPWPGPNRVAEVKAEGFNLLSKECYSLTGKQSSAESDAWVLQFGEAENRLLMGGCRNKCLSVLKTLRDRHLELPGQPLNNYHMKTLLLYECEKHPRETDWDEACLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALESAAKQTWRLAREILTNPKSLDKL

Target ORF information:

RefSeq Version	NM_011839.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus mab-21-like 2 (C. elegans) (Mab21l2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011839.3

ORF Insert Sequence:

ATGATCGCCG CTCAGGCCAA GCTGGTTTAC CAGCTCAATA AATACTACAC CGAGCGCTGC 
CAGGCGCGCA AGGCTGCGAT CGCCAAGACC ATCCGAGAAG TCTGCAAGGT AGTGTCGGAT 
GTGCTAAAGG AAGTGGAGGT GCAAGAGCCC CGCTTCATCA GCTCTCTGAG TGAGATTGAC 
GCCCGCTACG AGGGGCTGGA GGTAATCTCG CCCACCGAGT TCGAGGTGGT ACTCTACCTC 
AACCAGATGG GAGTCTTCAA CTTCGTGGAC GACGGATCTC TGCCCGGCTG TGCCGTGCTC 
AAACTAAGCG ATGGGCGGAA GCGGAGCATG TCTCTTTGGG TCGAGTTCAT CACAGCGTCT 
GGCTACCTTT CTGCGCGCAA GATCCGCTCG CGTTTCCAGA CACTAGTAGC CCAGGCGGTG 
GACAAGTGCA GCTACCGGGA CGTGGTCAAG ATGATCGCCG ACACTAGTGA GGTCAAGTTG 
CGCATCAGGG AGCGCTACGT GGTGCAAATC ACCCCAGCGT TCAAGTGCAC CGGGATCTGG 
CCTCGCAGCG CGGCACAGTG GCCTATGCCC CACATCCCCT GGCCCGGCCC CAATCGGGTG 
GCGGAGGTCA AGGCCGAAGG GTTCAACTTG CTCTCCAAGG AGTGCTACTC GCTGACTGGC 
AAGCAGAGCT CCGCAGAAAG CGACGCCTGG GTGCTGCAGT TCGGTGAGGC GGAGAACCGC 
TTGCTGATGG GCGGCTGTAG AAACAAGTGC CTCTCGGTGC TGAAGACGCT GCGGGACCGC 
CACCTGGAGC TGCCTGGCCA GCCGCTCAAT AACTACCACA TGAAGACGCT GCTGCTGTAC 
GAGTGCGAGA AACACCCGAG GGAAACGGAC TGGGACGAGG CTTGCTTGGG CGACCGTCTG 
AACGGCATCC TGCTACAGCT CATCTCCTGC CTGCAGTGCC GCCGCTGCCC TCACTACTTT 
TTGCCCAACC TCGACCTCTT CCAGGGTAAG CCCCACTCGG CCCTGGAGAG CGCTGCCAAG 
CAGACCTGGA GATTGGCCAG GGAAATCCTC ACCAATCCCA AAAGCTTGGA CAAACTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Mab21l2 ( NM_011839.4 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_035969.2 Mus musculus mab-21-like 2 (Mab21l2), mRNA.

Price & Availability↑

CloneID	OMu58268
Clone ID Related Accession (Same CDS sequence)	NM_011839.3 , NM_011839.4
Accession Version	NM_011839.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1080bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Mus musculus(house mouse)
Product	protein mab-21-like 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK053645.1 and BC058730.1. On Apr 12, 2018 this sequence version replaced NM_011839.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: BC058730.1 [ECO:0000345] ##Evidence-Data-END##

ATGATCGCCG CTCAGGCCAA GCTGGTTTAC CAGCTCAATA AATACTACAC CGAGCGCTGC 
CAGGCGCGCA AGGCTGCGAT CGCCAAGACC ATCCGAGAAG TCTGCAAGGT AGTGTCGGAT 
GTGCTAAAGG AAGTGGAGGT GCAAGAGCCC CGCTTCATCA GCTCTCTGAG TGAGATTGAC 
GCCCGCTACG AGGGGCTGGA GGTAATCTCG CCCACCGAGT TCGAGGTGGT ACTCTACCTC 
AACCAGATGG GAGTCTTCAA CTTCGTGGAC GACGGATCTC TGCCCGGCTG TGCCGTGCTC 
AAACTAAGCG ATGGGCGGAA GCGGAGCATG TCTCTTTGGG TCGAGTTCAT CACAGCGTCT 
GGCTACCTTT CTGCGCGCAA GATCCGCTCG CGTTTCCAGA CACTAGTAGC CCAGGCGGTG 
GACAAGTGCA GCTACCGGGA CGTGGTCAAG ATGATCGCCG ACACTAGTGA GGTCAAGTTG 
CGCATCAGGG AGCGCTACGT GGTGCAAATC ACCCCAGCGT TCAAGTGCAC CGGGATCTGG 
CCTCGCAGCG CGGCACAGTG GCCTATGCCC CACATCCCCT GGCCCGGCCC CAATCGGGTG 
GCGGAGGTCA AGGCCGAAGG GTTCAACTTG CTCTCCAAGG AGTGCTACTC GCTGACTGGC 
AAGCAGAGCT CCGCAGAAAG CGACGCCTGG GTGCTGCAGT TCGGTGAGGC GGAGAACCGC 
TTGCTGATGG GCGGCTGTAG AAACAAGTGC CTCTCGGTGC TGAAGACGCT GCGGGACCGC 
CACCTGGAGC TGCCTGGCCA GCCGCTCAAT AACTACCACA TGAAGACGCT GCTGCTGTAC 
GAGTGCGAGA AACACCCGAG GGAAACGGAC TGGGACGAGG CTTGCTTGGG CGACCGTCTG 
AACGGCATCC TGCTACAGCT CATCTCCTGC CTGCAGTGCC GCCGCTGCCC TCACTACTTT 
TTGCCCAACC TCGACCTCTT CCAGGGTAAG CCCCACTCGG CCCTGGAGAG CGCTGCCAAG 
CAGACCTGGA GATTGGCCAG GGAAATCCTC ACCAATCCCA AAAGCTTGGA CAAACTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_035969.2
CDS	593..1672
Translation	MIAAQAKLVYQLNKYYTERCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLSEIDARYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMIADTSEVKLRIRERYVVQITPAFKCTGIWPRSAAQWPMPHIPWPGPNRVAEVKAEGFNLLSKECYSLTGKQSSAESDAWVLQFGEAENRLLMGGCRNKCLSVLKTLRDRHLELPGQPLNNYHMKTLLLYECEKHPRETDWDEACLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALESAAKQTWRLAREILTNPKSLDKL

Target ORF information:

RefSeq Version	NM_011839.4
Organism	Mus musculus(house mouse)
Definition	Mus musculus mab-21-like 2 (Mab21l2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_011839.4

ORF Insert Sequence:

ATGATCGCCG CTCAGGCCAA GCTGGTTTAC CAGCTCAATA AATACTACAC CGAGCGCTGC 
CAGGCGCGCA AGGCTGCGAT CGCCAAGACC ATCCGAGAAG TCTGCAAGGT AGTGTCGGAT 
GTGCTAAAGG AAGTGGAGGT GCAAGAGCCC CGCTTCATCA GCTCTCTGAG TGAGATTGAC 
GCCCGCTACG AGGGGCTGGA GGTAATCTCG CCCACCGAGT TCGAGGTGGT ACTCTACCTC 
AACCAGATGG GAGTCTTCAA CTTCGTGGAC GACGGATCTC TGCCCGGCTG TGCCGTGCTC 
AAACTAAGCG ATGGGCGGAA GCGGAGCATG TCTCTTTGGG TCGAGTTCAT CACAGCGTCT 
GGCTACCTTT CTGCGCGCAA GATCCGCTCG CGTTTCCAGA CACTAGTAGC CCAGGCGGTG 
GACAAGTGCA GCTACCGGGA CGTGGTCAAG ATGATCGCCG ACACTAGTGA GGTCAAGTTG 
CGCATCAGGG AGCGCTACGT GGTGCAAATC ACCCCAGCGT TCAAGTGCAC CGGGATCTGG 
CCTCGCAGCG CGGCACAGTG GCCTATGCCC CACATCCCCT GGCCCGGCCC CAATCGGGTG 
GCGGAGGTCA AGGCCGAAGG GTTCAACTTG CTCTCCAAGG AGTGCTACTC GCTGACTGGC 
AAGCAGAGCT CCGCAGAAAG CGACGCCTGG GTGCTGCAGT TCGGTGAGGC GGAGAACCGC 
TTGCTGATGG GCGGCTGTAG AAACAAGTGC CTCTCGGTGC TGAAGACGCT GCGGGACCGC 
CACCTGGAGC TGCCTGGCCA GCCGCTCAAT AACTACCACA TGAAGACGCT GCTGCTGTAC 
GAGTGCGAGA AACACCCGAG GGAAACGGAC TGGGACGAGG CTTGCTTGGG CGACCGTCTG 
AACGGCATCC TGCTACAGCT CATCTCCTGC CTGCAGTGCC GCCGCTGCCC TCACTACTTT 
TTGCCCAACC TCGACCTCTT CCAGGGTAAG CCCCACTCGG CCCTGGAGAG CGCTGCCAAG 
CAGACCTGGA GATTGGCCAG GGAAATCCTC ACCAATCCCA AAAGCTTGGA CAAACTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Monoallelic and biallelic mutations in MAB21L2 cause a spectrum of major eye malformations.
American journal of human genetics94(6)915-23(2014 Jun)
Rainger J,Pehlivan D,Johansson S,Bengani H,Sanchez-Pulido L,Williamson KA,Ture M,Barker H,Rosendahl K,Spranger J,Horn D,Meynert A,Floyd JA,Prescott T,Anderson CA,Rainger JK,Karaca E,Gonzaga-Jauregui C,Jhangiani S,Muzny DM,Seawright A,Soares DC,Kharbanda M,Murday V,Finch A,,,Gibbs RA,van Heyningen V,Taylor MS,Yakut T,Knappskog PM,Hurles ME,Ponting CP,Lupski JR,Houge G,FitzPatrick DR

Genetic analysis of the role of Alx4 in the coordination of lower body and external genitalia formation.
European journal of human genetics : EJHG22(3)350-7(2014 Mar)
Matsumaru D,Haraguchi R,Moon AM,Satoh Y,Nakagata N,Yamamura K,Takahashi N,Kitazawa S,Yamada G

Differential expression of Meis2, Mab21l2 and Tbx3 during limb development associated with diversification of limb morphology in mammals.
PloS one9(8)e106100(2014)
Dai M,Wang Y,Fang L,Irwin DM,Zhu T,Zhang J,Zhang S,Wang Z

The septum transversum mesenchyme induces gall bladder development.
Biology open2(8)779-88(2013 Aug)
Saito Y,Kojima T,Takahashi N