Ring1 cDNA ORF clone, Mus musculus(house mouse)

Polycomb directs timely activation of germline genes in spermatogenesis.
Maezawa S, Hasegawa K, Yukawa M, Sakashita A, Alavattam KG, Andreassen PR, Vidal M, Koseki H, Barski A, Namekawa SH
Genes & development31(16)1693-1703(2017 Aug)

Conversion of T cells to B cells by inactivation of polycomb-mediated epigenetic suppression of the B-lineage program.
Ikawa T, Masuda K, Endo TA, Endo M, Isono K, Koseki Y, Nakagawa R, Kometani K, Takano J, Agata Y, Katsura Y, Kurosaki T, Vidal M, Koseki H, Kawamoto H
Genes & development30(22)2475-2485(2016 Nov)

Data suggest that the RING1-MEIS1/2 axis is regulated by early PD signals and contributes to the initiation or maintenance of the distal signal circuitry.
Title: RING1 proteins contribute to early proximal-distal specification of the forelimb bud by restricting Meis2 expression.

identification of gene-dosage-dependent roles in primordial germ cell development for Ring1 and Rnf2, two central components of the Polycomb repressive complex 1 (PRC1)
Title: PRC1 coordinates timing of sexual differentiation of female primordial germ cells.

loss of Ring1a/b postnatally results in defective cervical loops and disturbances of enamel and dentin formation in continuously growing incisors
Title: Ring1a/b polycomb proteins regulate the mesenchymal stem cell niche in continuously growing incisors.

Studies in mammalian cells have found a multiplicity of protein complexes containing Ring1A and Ring1B, suggesting an expanded regulatory role for Ring1A, Ring1B proteins in the epigenetic regulation of gene expression.
Title: Role of polycomb proteins Ring1A and Ring1B in the epigenetic regulation of gene expression.

Ring1A/B-mediated Polycomb silencing functions downstream of the core transcriptional regulatory circuitry to maintain ES cell identity
Title: Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity.