Septin5 cDNA ORF clone, Mus musculus(house mouse)

Ranbp1, Deleted in DiGeorge/22q11.2 Deletion Syndrome, is a Microcephaly Gene That Selectively Disrupts Layer 2/3 Cortical Projection Neuron Generation.
Paronett EM, Meechan DW, Karpinski BA, LaMantia AS, Maynard TM
Cerebral cortex (New York, N.Y. : 1991)25(10)3977-93(2015 Oct)

The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.
Ray JP, Staron MM, Shyer JA, Ho PC, Marshall HD, Gray SM, Laidlaw BJ, Araki K, Ahmed R, Kaech SM, Craft J
Immunity43(4)690-702(2015 Oct)

Dysphagia and disrupted cranial nerve development in a mouse model of DiGeorge (22q11) deletion syndrome.
Karpinski BA, Maynard TM, Fralish MS, Nuwayhid S, Zohn IE, Moody SA, LaMantia AS
Disease models & mechanisms7(2)245-57(2014 Feb)

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)

Septins promote dendrite and axon development by negatively regulating microtubule stability via HDAC6-mediated deacetylation.
Ageta-Ishihara N, Miyata T, Ohshima C, Watanabe M, Sato Y, Hamamura Y, Higashiyama T, Mazitschek R, Bito H, Kinoshita M
Nature communications42532(2013)

Congenic knockout mice and mice overexpressing Sept5 in the hippocampus or amygdala were indistinguishable from control mice in novelty and olfactory responses, anxiety or motor activity
Title: Alterations of social interaction through genetic and environmental manipulation of the 22q11.2 gene Sept5 in the mouse brain.

Report SEPT4/5/7 expression in mouse cochlea and roles in auditory function.
Title: Localization of septin proteins in the mouse cochlea.

The result of this study suggested that Septin 5 is a core molecular substrate that differentiates distinct release modalities at the central synapse.
Title: Septins regulate developmental switching from microdomain to nanodomain coupling of Ca(2+) influx to neurotransmitter release at a central synapse.

Here, we showed existence of two Sept5 isoforms in the mouse and studied their tissue and developmental expressions that would be helpful for exploring isoform specific function.
Title: Neuronal expression of two isoforms of mouse Septin 5.

Sept5 deficiency exerts pleiotropic effects on a select set of affective behaviors and cognitive processes.
Title: Sept5 deficiency exerts pleiotropic influence on affective behaviors and cognitive functions in mice.