Mageb3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Mageb3
Entrez Gene ID	17147
Full Name	melanoma antigen, family B, 3
Synonyms	Mage-b3,Mage-ps1,Mage-rs3,Smage3
General protein information	Preferred Names melanoma antigen, family B, 3 Names melanoma antigen family B, 3
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2\|2 E5

mRNA and Protein(s)

mRNA	Protein	Name
NM_008545.2	NP_032571.2	melanoma antigen family B, 3

Pathways from BioSystems

Homologies

	MAGEB1	XP_001094809.1
Homo sapiens (human)	MAGEB1	NP_803134.1
Pan troglodytes (chimpanzee)	MAGEB1	XP_528921.2
Mus musculus (house mouse)	Mageb3	NP_032571.2
Mus musculus (house mouse)	Mageb2	NP_112448.1
Mus musculus (house mouse)	Mageb1	NP_034889.1
Canis lupus familiaris (dog)	LOC491795	XP_548914.1

Gene Ontology
Bibliography

Related articles in PubMed

Potential mouse tumor model for pre-clinical testing of mage-specific breast cancer vaccines.
Sypniewska RK, Hoflack L, Bearss DJ, Gravekamp C
Breast cancer research and treatment74(3)221-33(2002 Jun)

An overview of the MAGE gene family with the identification of all human members of the family.
Chomez P, De Backer O, Bertrand M, De Plaen E, Boon T, Lucas S
Cancer research61(14)5544-51(2001 Jul)

A new family of mouse genes homologous to the human MAGE genes.
De Plaen E, De Backer O, Arnaud D, Bonjean B, Chomez P, Martelange V, Avner P, Baldacci P, Babinet C, Hwang SY, Knowles B, Boon T
Genomics55(2)176-84(1999 Jan)

The SMAGE gene family is expressed in post-meiotic spermatids during mouse germ cell differentiation.
Chomez P, Williams R, De Backer O, Boon T, Vennstr?m B
Immunogenetics43(1-2)97-100(1996)

Structure, chromosomal location, and expression pattern of three mouse genes homologous to the human MAGE genes.
De Backer O, Verheyden AM, Martin B, Godelaine D, De Plaen E, Brasseur R, Avner P, Boon T
Genomics28(1)74-83(1995 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

mammary tumor expression of mage-b3 TAA has been demonstrated
Title: Potential mouse tumor model for pre-clinical testing of mage-specific breast cancer vaccines.

The following Mageb3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mageb3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu24677	NM_008545.2 Latest version!	Mus musculus melanoma antigen, family B, 3 (Mageb3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Mageb3 ( NM_008545.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_032571.2 Mus musculus melanoma antigen, family B, 3 (Mageb3), mRNA.

Price & Availability↑

CloneID	OMu24677
Clone ID Related Accession (Same CDS sequence)	NM_008545.2
Accession Version	NM_008545.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 993bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-25
Organism	Mus musculus(house mouse)
Product	melanoma antigen family B, 3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK019658.1. On Jun 9, 2003 this sequence version replaced NM_008545.1. ##Evidence-Data-START## Transcript is intronless :: AK019658.1 [ECO:0000345] ##Evidence-Data-END##

ATGCCTAGGG GTCAAAAGAG TAAGAGCCGC TCCCGTGCTA AACGACAGCA GTCACGCAGG 
GAGGTTCAAG TAGTTCAGCC CACTGCAGAG GAAGCAGGGT CTTCTCCTGT TGACCTGAGT 
GCTGGGTCCA GCTTCCCTGG TGGTTCTGCT CCTCAGGGTG TGAAAAACCC TGGATCTTTT 
GGTGCAGGTG TATCCTGCAC AGGCTCTGGT ATAGGTGGTA GAAATGCTAC TGTCCTGCCT 
GATACAAAAA GTTCAGATGG CACCCAGGCA GGGACTTCCA TTCAGCACAC ACTGAAAGAT 
CCTATCATGA GGAAGGCTAG TGTGCTGATA GAATTCCTGC TAGATAAATT TAAGATGAAA 
GAAGCAGTTA CAAGAAGTGA AATGCTGGCA GTAGTTAACA AGAAGTATAA GGAGCAATTC 
CCTGAGATCC TCAGGAGAAC TTCTGCACGC CTAGAATTGG TCTTTGGTCT TGAGTTGAAG 
GAAATTGATC CCAGCACTCA TTCCTATTTG CTGGTGGGCA AACTGGGTCT TTCCACTGAG 
GGAAGTTTGA GTAGTAACTG GGGGTTGCCT AGGACAGGTC TCCTAATGTC TGTCCTAGGT 
GTGATCTTCA TGAAGGGTAA CCGTGCCACT GAGCAAGAGG TCTGGCAATT TCTGCATGGA 
GTGGGGGTAT ATGCTGGGAA GAAGCACTTG ATCTTTGGCG AGCCTGAGGA GTTTATAAGA 
GATGTAGTGC AGGAAAATTA CCTGGAGTAC CGCCAGGTAC CTGGCAGTGA TCCCCCAAGC 
TATGAGTTCC TGTGGGGACC CAGAGCCCAT GCTGAAACAA CCAAGATGAA AGTCCTGAAA 
GTTTTAGCTA AAGTCAATGG CACAGTCCCT AGTGCCTTCC CTAATCTCTA CCAGTTGGCT 
CTTAGAGATC AGGCAGGAGG GGTGCCAAGA AGTAGAGTTC AAGGCAAGGG TGTTCATTCC 
AAGGCCCCAT CCCAAAAGTC CTCTAATGTG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_032571.2
CDS	874..1866
Translation	MPRGQKSKSRSRAKRQQSRREVQVVQPTAEEAGSSPVDLSAGSSFPGGSAPQGVKNPGSFGAGVSCTGSGIGGRNATVLPDTKSSDGTQAGTSIQHTLKDPIMRKASVLIEFLLDKFKMKEAVTRSEMLAVVNKKYKEQFPEILRRTSARLELVFGLELKEIDPSTHSYLLVGKLGLSTEGSLSSNWGLPRTGLLMSVLGVIFMKGNRATEQEVWQFLHGVGVYAGKKHLIFGEPEEFIRDVVQENYLEYRQVPGSDPPSYEFLWGPRAHAETTKMKVLKVLAKVNGTVPSAFPNLYQLALRDQAGGVPRSRVQGKGVHSKAPSQKSSNV

Target ORF information:

RefSeq Version	NM_008545.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus melanoma antigen, family B, 3 (Mageb3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_008545.2

ORF Insert Sequence:

ATGCCTAGGG GTCAAAAGAG TAAGAGCCGC TCCCGTGCTA AACGACAGCA GTCACGCAGG 
GAGGTTCAAG TAGTTCAGCC CACTGCAGAG GAAGCAGGGT CTTCTCCTGT TGACCTGAGT 
GCTGGGTCCA GCTTCCCTGG TGGTTCTGCT CCTCAGGGTG TGAAAAACCC TGGATCTTTT 
GGTGCAGGTG TATCCTGCAC AGGCTCTGGT ATAGGTGGTA GAAATGCTAC TGTCCTGCCT 
GATACAAAAA GTTCAGATGG CACCCAGGCA GGGACTTCCA TTCAGCACAC ACTGAAAGAT 
CCTATCATGA GGAAGGCTAG TGTGCTGATA GAATTCCTGC TAGATAAATT TAAGATGAAA 
GAAGCAGTTA CAAGAAGTGA AATGCTGGCA GTAGTTAACA AGAAGTATAA GGAGCAATTC 
CCTGAGATCC TCAGGAGAAC TTCTGCACGC CTAGAATTGG TCTTTGGTCT TGAGTTGAAG 
GAAATTGATC CCAGCACTCA TTCCTATTTG CTGGTGGGCA AACTGGGTCT TTCCACTGAG 
GGAAGTTTGA GTAGTAACTG GGGGTTGCCT AGGACAGGTC TCCTAATGTC TGTCCTAGGT 
GTGATCTTCA TGAAGGGTAA CCGTGCCACT GAGCAAGAGG TCTGGCAATT TCTGCATGGA 
GTGGGGGTAT ATGCTGGGAA GAAGCACTTG ATCTTTGGCG AGCCTGAGGA GTTTATAAGA 
GATGTAGTGC AGGAAAATTA CCTGGAGTAC CGCCAGGTAC CTGGCAGTGA TCCCCCAAGC 
TATGAGTTCC TGTGGGGACC CAGAGCCCAT GCTGAAACAA CCAAGATGAA AGTCCTGAAA 
GTTTTAGCTA AAGTCAATGG CACAGTCCCT AGTGCCTTCC CTAATCTCTA CCAGTTGGCT 
CTTAGAGATC AGGCAGGAGG GGTGCCAAGA AGTAGAGTTC AAGGCAAGGG TGTTCATTCC 
AAGGCCCCAT CCCAAAAGTC CTCTAATGTG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Potential mouse tumor model for pre-clinical testing of mage-specific breast cancer vaccines.
Breast cancer research and treatment74(3)221-33(2002 Jun)
Sypniewska RK,Hoflack L,Bearss DJ,Gravekamp C

An overview of the MAGE gene family with the identification of all human members of the family.
Cancer research61(14)5544-51(2001 Jul)
Chomez P,De Backer O,Bertrand M,De Plaen E,Boon T,Lucas S

A new family of mouse genes homologous to the human MAGE genes.
Genomics55(2)176-84(1999 Jan)
De Plaen E,De Backer O,Arnaud D,Bonjean B,Chomez P,Martelange V,Avner P,Baldacci P,Babinet C,Hwang SY,Knowles B,Boon T

The SMAGE gene family is expressed in post-meiotic spermatids during mouse germ cell differentiation.
Immunogenetics43(1-2)97-100(1996)
Chomez P,Williams R,De Backer O,Boon T,Vennstr?m B

Structure, chromosomal location, and expression pattern of three mouse genes homologous to the human MAGE genes.
Genomics28(1)74-83(1995 Jul)
De Backer O,Verheyden AM,Martin B,Godelaine D,De Plaen E,Brasseur R,Avner P,Boon T