Lalba cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lalba
Entrez Gene ID	16770
Full Name	lactalbumin, alpha
Synonyms	AW208827,Lyzg
General protein information	Preferred Names lactalbumin, alpha Names alpha-lactalbumin lactose synthase B protein lysozyme g
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 15 Map Location: 15\|15 F1

mRNA and Protein(s)

mRNA	Protein	Name
NM_010679.1	NP_034809.1	alpha-lactalbumin precursor
XM_006520517.1	XP_006520580.1	alpha-lactalbumin isoform X1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	LALBA	NP_776803.1
Homo sapiens (human)	LALBA	NP_002280.1
Canis lupus familiaris (dog)	LALBA	NP_001003129.1
Rattus norvegicus (Norway rat)	Lalba	NP_036726.1
Pan troglodytes (chimpanzee)	LALBA	XP_001160401.1
	LALBA	XP_001102116.1
Mus musculus (house mouse)	Lalba	NP_034809.1

Gene Ontology
Bibliography

Related articles in PubMed

Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.
Bulusu V, Prior N, Snaebjornsson MT, Kuehne A, Sonnen KF, Kress J, Stein F, Schultz C, Sauer U, Aulehla A
Developmental cell40(4)331-341.e4(2017 02)

Mutation of arginine 228 to lysine enhances the glucosyltransferase activity of bovine beta-1,4-galactosyltransferase I.
Ramakrishnan B, Boeggeman E, Qasba PK
Biochemistry44(9)3202-10(2005 Mar)

Apoptotic cell death in the lactating mammary gland is enhanced by a folding variant of alpha-lactalbumin.
Baltzer A, Svanborg C, Jaggi R
Cellular and molecular life sciences : CMLS61(10)1221-8(2004 May)

Hsp105 but not Hsp70 family proteins suppress the aggregation of heat-denatured protein in the presence of ADP.
Yamagishi N, Ishihara K, Saito Y, Hatayama T
FEBS letters555(2)390-6(2003 Dec)

The role of tryptophan 314 in the conformational changes of beta1,4-galactosyltransferase-I.
Ramasamy V, Ramakrishnan B, Boeggeman E, Qasba PK
Journal of molecular biology331(5)1065-76(2003 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

a folding variant of alpha-lactalbumin has a role in lactating mammary gland apoptosis
Title: Apoptotic cell death in the lactating mammary gland is enhanced by a folding variant of alpha-lactalbumin.

The following Lalba gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lalba cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu06602	NM_010679.1 Latest version!	Mus musculus lactalbumin, alpha (Lalba), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OMu06602	XM_006520517.1 Latest version!	Mus musculus lactalbumin, alpha (Lalba), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lalba ( NM_010679.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_034809.1 Mus musculus lactalbumin, alpha (Lalba), mRNA.

Price & Availability↑

CloneID	OMu06602
Clone ID Related Accession (Same CDS sequence)	NM_010679.1 , XM_006520517.1
Accession Version	NM_010679.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 432bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-03
Organism	Mus musculus(house mouse)
Product	alpha-lactalbumin precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from M80909.1. On Dec 7, 2005 this sequence version replaced XM_911937.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC069916.1, BC006922.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849381 [ECO:0000348] ##Evidence-Data-END##

ATGATGCATT TCGTTCCTTT GTTCCTGGTG TGTATTTTGT CGTTGCCTGC CTTTCAAGCC 
ACAGAGCTTA CAAAATGCAA GGTGTCCCAT GCCATTAAAG ACATAGATGG CTATCAAGGC 
ATCTCTTTGC TTGAATGGGC CTGTGTTTTA TTTCATACCA GTGGCTACGA CACACAAGCT 
GTTGTCAACG ACAACGGCAG CACAGAGTAC GGACTCTTCC AGATCAGTGA CAGATTTTGG 
TGTAAAAGTA GTGAGTTCCC CGAGTCGGAG AACATCTGTG GCATCTCCTG TGACAAGTTA 
TTGGATGACG AGTTGGATGA TGACATAGCG TGTGCCAAGA AGATCCTGGC TATCAAAGGA 
ATCGACTACT GGAAAGCCTA CAAGCCCATG TGCTCTGAGA AGCTTGAACA GTGGCGTTGT 
GAGAAGCCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_034809.1
CDS	13..444
Translation	MMHFVPLFLVCILSLPAFQATELTKCKVSHAIKDIDGYQGISLLEWACVLFHTSGYDTQAVVNDNGSTEYGLFQISDRFWCKSSEFPESENICGISCDKLLDDELDDDIACAKKILAIKGIDYWKAYKPMCSEKLEQWRCEKP

Target ORF information:

RefSeq Version	NM_010679.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus lactalbumin, alpha (Lalba), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_010679.1

ORF Insert Sequence:

ATGATGCATT TCGTTCCTTT GTTCCTGGTG TGTATTTTGT CGTTGCCTGC CTTTCAAGCC 
ACAGAGCTTA CAAAATGCAA GGTGTCCCAT GCCATTAAAG ACATAGATGG CTATCAAGGC 
ATCTCTTTGC TTGAATGGGC CTGTGTTTTA TTTCATACCA GTGGCTACGA CACACAAGCT 
GTTGTCAACG ACAACGGCAG CACAGAGTAC GGACTCTTCC AGATCAGTGA CAGATTTTGG 
TGTAAAAGTA GTGAGTTCCC CGAGTCGGAG AACATCTGTG GCATCTCCTG TGACAAGTTA 
TTGGATGACG AGTTGGATGA TGACATAGCG TGTGCCAAGA AGATCCTGGC TATCAAAGGA 
ATCGACTACT GGAAAGCCTA CAAGCCCATG TGCTCTGAGA AGCTTGAACA GTGGCGTTGT 
GAGAAGCCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lalba ( XM_006520517.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006520580.1 Mus musculus lactalbumin, alpha (Lalba), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu06602
Clone ID Related Accession (Same CDS sequence)	NM_010679.1 , XM_006520517.1
Accession Version	XM_006520517.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 432bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	alpha-lactalbumin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000081.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGCATT TCGTTCCTTT GTTCCTGGTG TGTATTTTGT CGTTGCCTGC CTTTCAAGCC 
ACAGAGCTTA CAAAATGCAA GGTGTCCCAT GCCATTAAAG ACATAGATGG CTATCAAGGC 
ATCTCTTTGC TTGAATGGGC CTGTGTTTTA TTTCATACCA GTGGCTACGA CACACAAGCT 
GTTGTCAACG ACAACGGCAG CACAGAGTAC GGACTCTTCC AGATCAGTGA CAGATTTTGG 
TGTAAAAGTA GTGAGTTCCC CGAGTCGGAG AACATCTGTG GCATCTCCTG TGACAAGTTA 
TTGGATGACG AGTTGGATGA TGACATAGCG TGTGCCAAGA AGATCCTGGC TATCAAAGGA 
ATCGACTACT GGAAAGCCTA CAAGCCCATG TGCTCTGAGA AGCTTGAACA GTGGCGTTGT 
GAGAAGCCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006520580.1
CDS	156..587
Translation	MMHFVPLFLVCILSLPAFQATELTKCKVSHAIKDIDGYQGISLLEWACVLFHTSGYDTQAVVNDNGSTEYGLFQISDRFWCKSSEFPESENICGISCDKLLDDELDDDIACAKKILAIKGIDYWKAYKPMCSEKLEQWRCEKP

Target ORF information:

RefSeq Version	XM_006520517.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus lactalbumin, alpha (Lalba), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006520517.1

ORF Insert Sequence:

ATGATGCATT TCGTTCCTTT GTTCCTGGTG TGTATTTTGT CGTTGCCTGC CTTTCAAGCC 
ACAGAGCTTA CAAAATGCAA GGTGTCCCAT GCCATTAAAG ACATAGATGG CTATCAAGGC 
ATCTCTTTGC TTGAATGGGC CTGTGTTTTA TTTCATACCA GTGGCTACGA CACACAAGCT 
GTTGTCAACG ACAACGGCAG CACAGAGTAC GGACTCTTCC AGATCAGTGA CAGATTTTGG 
TGTAAAAGTA GTGAGTTCCC CGAGTCGGAG AACATCTGTG GCATCTCCTG TGACAAGTTA 
TTGGATGACG AGTTGGATGA TGACATAGCG TGTGCCAAGA AGATCCTGGC TATCAAAGGA 
ATCGACTACT GGAAAGCCTA CAAGCCCATG TGCTCTGAGA AGCTTGAACA GTGGCGTTGT 
GAGAAGCCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.
Developmental cell40(4)331-341.e4(2017 02)
Bulusu V,Prior N,Snaebjornsson MT,Kuehne A,Sonnen KF,Kress J,Stein F,Schultz C,Sauer U,Aulehla A

Mutation of arginine 228 to lysine enhances the glucosyltransferase activity of bovine beta-1,4-galactosyltransferase I.
Biochemistry44(9)3202-10(2005 Mar)
Ramakrishnan B,Boeggeman E,Qasba PK

Apoptotic cell death in the lactating mammary gland is enhanced by a folding variant of alpha-lactalbumin.
Cellular and molecular life sciences : CMLS61(10)1221-8(2004 May)
Baltzer A,Svanborg C,Jaggi R

Hsp105 but not Hsp70 family proteins suppress the aggregation of heat-denatured protein in the presence of ADP.
FEBS letters555(2)390-6(2003 Dec)
Yamagishi N,Ishihara K,Saito Y,Hatayama T

The role of tryptophan 314 in the conformational changes of beta1,4-galactosyltransferase-I.
Journal of molecular biology331(5)1065-76(2003 Aug)
Ramasamy V,Ramakrishnan B,Boeggeman E,Qasba PK