Rhob cDNA ORF clone, Mus musculus(house mouse)

Kctd13 deletion reduces synaptic transmission via increased RhoA.
Escamilla CO, Filonova I, Walker AK, Xuan ZX, Holehonnur R, Espinosa F, Liu S, Thyme SB, L?pez-Garc?a IA, Mendoza DB, Usui N, Ellegood J, Eisch AJ, Konopka G, Lerch JP, Schier AF, Speed HE, Powell CM
Nature551(7679)227-231(2017 Nov)

the histone deacetylase inhibitor trichostatin A increased miR-223 expression obviously in TLR-triggered macrophages, which in turn suppressed RhoB expression and downstream IL-6 production, suggesting that the inhibition of miR-223 by histone deacetylation may be involved in the regulation of TLR-activated inflammatory response.
Title: Downregulated expression of miR-223 promotes Toll-like receptor-activated inflammatory responses in macrophages by targeting RhoB.

We show that RhoA mRNA levels were significantly higher compared with the RhoB mRNA levels in ESCs as well in various cancer cell lines and this difference could be accounted for by differences in the activities of the corresponding promoters.
Title: Functional analysis of the promoters of the small GTPases RhoA and RhoB in embryonic stem cells.

these results suggest that RhoB plays an important role in the hypoxia-induced activation of macrophages and the inflammatory response.
Title: RhoB regulates the function of macrophages in the hypoxia-induced inflammatory response.

Active RhoA and RhoB are involved in back end functions, such as retracting the tail and lamellipodial membrane extensions during macrophage migration.
Title: Mouse macrophages completely lacking Rho subfamily GTPases (RhoA, RhoB, and RhoC) have severe lamellipodial retraction defects, but robust chemotactic navigation and altered motility.

RhoB-deficient cells accumulate endogenous gammaH2AX and chromosomal abnormalities, suggesting that RhoB loss increases double-strand break-mediated genomic instability and tumor progression.
Title: RhoB promotes ?H2AX dephosphorylation and DNA double-strand break repair.