Abcb7 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Abcb7
Entrez Gene ID	11306
Full Name	ATP-binding cassette, sub-family B (MDR/TAP), member 7
Synonyms	AA517758,AU019072,Abc7
General protein information	Preferred Names ATP-binding cassette, sub-family B (MDR/TAP), member 7 Names ATP-binding cassette sub-family B member 7, mitochondrial ABC transporter 7 protein ATP-binding cassette 7 ATP-binding cassette transporter 7
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: X Map Location: X D\|X 46.58 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_009592.1	NP_033722.1	ATP-binding cassette sub-family B member 7, mitochondrial

Pathways from BioSystems

Homologies

Homo sapiens (human)	ABCB7	NP_001258625.1
	ABCB7	XP_001097352.2
Bos taurus (cattle)	ABCB7	NP_001179712.1
Caenorhabditis elegans (roundworm)	abtm-1	NP_001021830.1
Eremothecium gossypii	AGOS_AGL335W	NP_986332.1
Schizosaccharomyces pombe (fission yeast)	atm1	NP_594288.2
Magnaporthe oryzae (rice blast fungus)	MGG_03406	XP_003716534.1
Neurospora crassa	NCU05029	XP_956337.2
Gallus gallus (chicken)	ABCB7	XP_420301.1
Arabidopsis thaliana (thale cress)	ATM2	NP_194591.1
Arabidopsis thaliana (thale cress)	ATM3	NP_200635.1
Canis lupus familiaris (dog)	ABCB7	XP_549087.1
Rattus norvegicus (Norway rat)	Abcb7	NP_997683.1
Pan troglodytes (chimpanzee)	ABCB7	XP_003317575.1
Danio rerio (zebrafish)	abcb7	XP_694879.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006364	XP_001688853.1
Xenopus tropicalis (tropical clawed frog)	abcb7	XP_002931834.1
Mus musculus (house mouse)	Abcb7	NP_033722.1
Drosophila melanogaster (fruit fly)	ABCB7	NP_728642.2
Saccharomyces cerevisiae (baker's yeast)	ATM1	NP_014030.1
Kluyveromyces lactis	KLLA0A10131g	XP_451443.1
Arabidopsis thaliana (thale cress)	ATM1	NP_567813.1

Gene Ontology
Bibliography

Related articles in PubMed

Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass.
Borensztein M, Okamoto I, Syx L, Guilbaud G, Picard C, Ancelin K, Galupa R, Diabangouaya P, Servant N, Barillot E, Surani A, Saitou M, Chen CJ, Anastassiadis K, Heard E
Nature communications8(1)1297(2017 Nov)

Iron regulatory protein 1 sustains mitochondrial iron loading and function in frataxin deficiency.
Martelli A, Schmucker S, Reutenauer L, Mathieu JR, Peyssonnaux C, Karim Z, Puy H, Galy B, Hentze MW, Puccio H
Cell metabolism21(2)311-22(2015 Feb)

Transcription precedes loss of Xist coating and depletion of H3K27me3 during X-chromosome reprogramming in the mouse inner cell mass.
Williams LH, Kalantry S, Starmer J, Magnuson T
Development (Cambridge, England)138(10)2049-57(2011 May)

Dual mitochondrial localization and different roles of the reversible reaction of mammalian ferrochelatase.
Sakaino M, Ishigaki M, Ohgari Y, Kitajima S, Masaki R, Yamamoto A, Taketani S
The FEBS journal276(19)5559-70(2009 Oct)

Evidence of Xist RNA-independent initiation of mouse imprinted X-chromosome inactivation.
Kalantry S, Purushothaman S, Bowen RB, Starmer J, Magnuson T
Nature460(7255)647-51(2009 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Abcb7 is an essential gene associated with X-linked parent of origin lethality in mice and required for development or maintenance of adult cell lineages.
Title: The mitochondrial ATP-binding cassette transporter Abcb7 is essential in mice and participates in cytosolic iron-sulfur cluster biogenesis.

ABC7 positively regulates the expression of extramitochondrial thioredoxin & that of an intramitochondrial iron-sulfur-containing protein, ferrochelatase. ABC7 contributes to the production of heme during the differentiation of erythroid cells.
Title: Involvement of ABC7 in the biosynthesis of heme in erythroid cells: interaction of ABC7 with ferrochelatase.

The following Abcb7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Abcb7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu21362	NM_009592.1 Latest version!	Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 7 (Abcb7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$440.30 $629.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Abcb7 ( NM_009592.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_033722.1 Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 7 (Abcb7), mRNA.

Price & Availability↑

CloneID	OMu21362
Clone ID Related Accession (Same CDS sequence)	NM_009592.1
Accession Version	NM_009592.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2259bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Mus musculus(house mouse)
Product	ATP-binding cassette sub-family B member 7, mitochondrial
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB612154.1, AK152535.1, AK040069.1 and AL663052.8. On or before Mar 2, 2008 this sequence version replaced XM_907304.2, XM_920355.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC151037.1, SRR1660813.47401.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGCTGC TCGCGATACA TTCCTGGCGC TGGGCAGCCG CGGCGGTCGC TTTCGAAAAG 
CACAAGCATT CGGCAGTTCT GACCCGGGCT CTAGTCTCCA TGTGCGGCTC AGGCCCGCGA 
TGGAGTTCGT CCCAGCGCGG CGCGTCAGGA AGCGCTCGGC TGTCCCAGAC TACAGAATCA 
TTAAGAAATA CTACACAGCA GAGATGGGGA AAAGACAACT CCAGACAGTT ACTAGATGCT 
ACAAAGGCTC TCCAGACATG GCCATTGATA GAAAAGAGAA CATGTTGGCA TGGGCACGCA 
GGAGGAGGAC TCCACACAGA CCCAAAAGAA GGGTTAAAGG ATGTTGATAC TAGAAAAATC 
ATCAAAGCCA TGCTTTCTTA TGTGTGGCCT GAAGATAGGC CAGATCTACG AGCCAGAGTT 
GCCATCTCCC TGGGATTTTT GGGTGGTGCA AAGGCCATGA ATATTGTGGT TCCTTTCATG 
TTTAAATATG CTGTAGACAG CCTCAACCAG ATGTCGGGAA ACATGCTGAA CCTGAGTGAT 
GCACCAAATA CAGTTGCAAC CATGGCAACA GCAGTTCTGA TTGGCTATGG TGTATCAAGA 
GCCGGAGCTG CCTTTTTCAA TGAAGTTCGA AATGCAGTAT TTGGCAAAGT AGCACAAAAT 
TCAATACGAA GAATAGCCAA AAATGTATTT CTCCATCTCC ACAACTTGGA TCTGGGTTTC 
CATCTGAGCA GACAGACAGG AGCTTTATCT AAGGCTATTG ACAGAGGAAC AAGGGGCATT 
AGTTTTGTCC TCAGTGCGTT AGTATTTAAT CTTCTCCCTA TTGTGTTTGA GATGATGCTT 
GTCAGTAGTG TTTTGTATTA CAAATGTGGT GCCCAGTTTG CATTGGTAAC CCTAGGAACA 
CTTGGTGCAT ATACAGCATT CACAGTTGCA GTTACACGGT GGAGAACTAG ATTTAGAATA 
GAAATGAACA AAGCAGATAA CGATGCAGGT AATGCTGCTA TCGACTCACT GCTGAATTAT 
GAAACTGTGA AGTATTTTAA TAATGAAAAA TATGAAGCAC AAAGATATGA TGGATTCCTG 
AAGACATATG AGACTGCTTC ATTGAAAAGT ACCTCTACTC TGGCAATGCT GAATTTTGGC 
CAAAATGCTA TTTTCAGTGT CGGATTAACA GCTATAATGG TGCTTGCCAG TCAGGGAATT 
GTGGCAGGTG CCCTTACTGT TGGAGATCTA GTGATGGTGA ATGGACTGCT TTTTCAACTG 
TCATTACCCC TTAACTTCCT GGGAACTGTA TATAGAGAGA CAAGACAAGC ACTCATAGAT 
ATGAACACCT TGTTTACTCT GCTCAAGGTA GACACACGGA TTAAAGACAA AGTGATGGCA 
CCTCCCCTTC AAATAACACC ACAGACAGCC ACGGTGGCCT TTGATAATGT GCATTTTGAA 
TACATCGAAG GACAGAAAGT CCTTAATGGA GTATCTTTTG AAGTCCCTGC AGGAAAGAAA 
GTGGCCATTG TAGGAGGTAG TGGGTCAGGA AAAAGCACGA TAGTGAGGCT GCTGTTTCGC 
TTCTATGAGC CTCAAAAGGG TAGCATTTAC CTTGCTGGTC AAAATTTACA AGATGTGAGC 
CTGGAAAGTC TTCGGCGGGC AGTGGGAGTA GTACCTCAGG ATGCTGTCCT CTTCCATAAT 
ACCATCTACT ACAACCTCTT ATATGGAAAC ATCAATGCTT CACCTGAGGA AGTATATGCA 
GTCGCAAAAT TAGCTGGTCT TCATGATGCA ATTCTTCGAA TGCCACATGG ATATGACACA 
CAAGTAGGAG AACGAGGACT CAAGCTATCA GGCGGAGAAA AGCAGAGGGT AGCAATTGCA 
AGAGCCATTT TGAAGAATCC CCCAGTTATT CTCTATGATG AAGCTACTTC ATCATTAGAT 
TCAATTACTG AAGAGACTAT TCTTGGTGCC ATGAGAGATG TGGTCAAGCA CAGAACTTCT 
ATTTTCATTG CACATAGATT GTCAACAGTG GTTGATGCAG ATGAAATCAT TGTCCTGAGC 
CAGGGGAAGG TAGCTGAACG TGGTACCCAC TATGGTCTGC TTGCTAACTC TAGCAGTATC 
TATTCAGAGA TGTGGCATAC ACAGAGCAAC CGTGTACAGA ACCAGGATAG CCTCGGATGG 
GATGCAAAGA AAGAGAGTCT CTCCAAAGAG GAGGAAAGAA AGAAGCTCCA AGAAGAAATT 
GTCAACAGTG TGAAAGGCTG TGGAAATTGT TCCTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_033722.1
CDS	23..2281
Translation	MALLAIHSWRWAAAAVAFEKHKHSAVLTRALVSMCGSGPRWSSSQRGASGSARLSQTTESLRNTTQQRWGKDNSRQLLDATKALQTWPLIEKRTCWHGHAGGGLHTDPKEGLKDVDTRKIIKAMLSYVWPEDRPDLRARVAISLGFLGGAKAMNIVVPFMFKYAVDSLNQMSGNMLNLSDAPNTVATMATAVLIGYGVSRAGAAFFNEVRNAVFGKVAQNSIRRIAKNVFLHLHNLDLGFHLSRQTGALSKAIDRGTRGISFVLSALVFNLLPIVFEMMLVSSVLYYKCGAQFALVTLGTLGAYTAFTVAVTRWRTRFRIEMNKADNDAGNAAIDSLLNYETVKYFNNEKYEAQRYDGFLKTYETASLKSTSTLAMLNFGQNAIFSVGLTAIMVLASQGIVAGALTVGDLVMVNGLLFQLSLPLNFLGTVYRETRQALIDMNTLFTLLKVDTRIKDKVMAPPLQITPQTATVAFDNVHFEYIEGQKVLNGVSFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQKGSIYLAGQNLQDVSLESLRRAVGVVPQDAVLFHNTIYYNLLYGNINASPEEVYAVAKLAGLHDAILRMPHGYDTQVGERGLKLSGGEKQRVAIARAILKNPPVILYDEATSSLDSITEETILGAMRDVVKHRTSIFIAHRLSTVVDADEIIVLSQGKVAERGTHYGLLANSSSIYSEMWHTQSNRVQNQDSLGWDAKKESLSKEEERKKLQEEIVNSVKGCGNCSC

Target ORF information:

RefSeq Version	NM_009592.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus ATP-binding cassette, sub-family B (MDR/TAP), member 7 (Abcb7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_009592.1

ORF Insert Sequence:

ATGGCGCTGC TCGCGATACA TTCCTGGCGC TGGGCAGCCG CGGCGGTCGC TTTCGAAAAG 
CACAAGCATT CGGCAGTTCT GACCCGGGCT CTAGTCTCCA TGTGCGGCTC AGGCCCGCGA 
TGGAGTTCGT CCCAGCGCGG CGCGTCAGGA AGCGCTCGGC TGTCCCAGAC TACAGAATCA 
TTAAGAAATA CTACACAGCA GAGATGGGGA AAAGACAACT CCAGACAGTT ACTAGATGCT 
ACAAAGGCTC TCCAGACATG GCCATTGATA GAAAAGAGAA CATGTTGGCA TGGGCACGCA 
GGAGGAGGAC TCCACACAGA CCCAAAAGAA GGGTTAAAGG ATGTTGATAC TAGAAAAATC 
ATCAAAGCCA TGCTTTCTTA TGTGTGGCCT GAAGATAGGC CAGATCTACG AGCCAGAGTT 
GCCATCTCCC TGGGATTTTT GGGTGGTGCA AAGGCCATGA ATATTGTGGT TCCTTTCATG 
TTTAAATATG CTGTAGACAG CCTCAACCAG ATGTCGGGAA ACATGCTGAA CCTGAGTGAT 
GCACCAAATA CAGTTGCAAC CATGGCAACA GCAGTTCTGA TTGGCTATGG TGTATCAAGA 
GCCGGAGCTG CCTTTTTCAA TGAAGTTCGA AATGCAGTAT TTGGCAAAGT AGCACAAAAT 
TCAATACGAA GAATAGCCAA AAATGTATTT CTCCATCTCC ACAACTTGGA TCTGGGTTTC 
CATCTGAGCA GACAGACAGG AGCTTTATCT AAGGCTATTG ACAGAGGAAC AAGGGGCATT 
AGTTTTGTCC TCAGTGCGTT AGTATTTAAT CTTCTCCCTA TTGTGTTTGA GATGATGCTT 
GTCAGTAGTG TTTTGTATTA CAAATGTGGT GCCCAGTTTG CATTGGTAAC CCTAGGAACA 
CTTGGTGCAT ATACAGCATT CACAGTTGCA GTTACACGGT GGAGAACTAG ATTTAGAATA 
GAAATGAACA AAGCAGATAA CGATGCAGGT AATGCTGCTA TCGACTCACT GCTGAATTAT 
GAAACTGTGA AGTATTTTAA TAATGAAAAA TATGAAGCAC AAAGATATGA TGGATTCCTG 
AAGACATATG AGACTGCTTC ATTGAAAAGT ACCTCTACTC TGGCAATGCT GAATTTTGGC 
CAAAATGCTA TTTTCAGTGT CGGATTAACA GCTATAATGG TGCTTGCCAG TCAGGGAATT 
GTGGCAGGTG CCCTTACTGT TGGAGATCTA GTGATGGTGA ATGGACTGCT TTTTCAACTG 
TCATTACCCC TTAACTTCCT GGGAACTGTA TATAGAGAGA CAAGACAAGC ACTCATAGAT 
ATGAACACCT TGTTTACTCT GCTCAAGGTA GACACACGGA TTAAAGACAA AGTGATGGCA 
CCTCCCCTTC AAATAACACC ACAGACAGCC ACGGTGGCCT TTGATAATGT GCATTTTGAA 
TACATCGAAG GACAGAAAGT CCTTAATGGA GTATCTTTTG AAGTCCCTGC AGGAAAGAAA 
GTGGCCATTG TAGGAGGTAG TGGGTCAGGA AAAAGCACGA TAGTGAGGCT GCTGTTTCGC 
TTCTATGAGC CTCAAAAGGG TAGCATTTAC CTTGCTGGTC AAAATTTACA AGATGTGAGC 
CTGGAAAGTC TTCGGCGGGC AGTGGGAGTA GTACCTCAGG ATGCTGTCCT CTTCCATAAT 
ACCATCTACT ACAACCTCTT ATATGGAAAC ATCAATGCTT CACCTGAGGA AGTATATGCA 
GTCGCAAAAT TAGCTGGTCT TCATGATGCA ATTCTTCGAA TGCCACATGG ATATGACACA 
CAAGTAGGAG AACGAGGACT CAAGCTATCA GGCGGAGAAA AGCAGAGGGT AGCAATTGCA 
AGAGCCATTT TGAAGAATCC CCCAGTTATT CTCTATGATG AAGCTACTTC ATCATTAGAT 
TCAATTACTG AAGAGACTAT TCTTGGTGCC ATGAGAGATG TGGTCAAGCA CAGAACTTCT 
ATTTTCATTG CACATAGATT GTCAACAGTG GTTGATGCAG ATGAAATCAT TGTCCTGAGC 
CAGGGGAAGG TAGCTGAACG TGGTACCCAC TATGGTCTGC TTGCTAACTC TAGCAGTATC 
TATTCAGAGA TGTGGCATAC ACAGAGCAAC CGTGTACAGA ACCAGGATAG CCTCGGATGG 
GATGCAAAGA AAGAGAGTCT CTCCAAAGAG GAGGAAAGAA AGAAGCTCCA AGAAGAAATT 
GTCAACAGTG TGAAAGGCTG TGGAAATTGT TCCTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass.
Nature communications8(1)1297(2017 Nov)
Borensztein M,Okamoto I,Syx L,Guilbaud G,Picard C,Ancelin K,Galupa R,Diabangouaya P,Servant N,Barillot E,Surani A,Saitou M,Chen CJ,Anastassiadis K,Heard E

Iron regulatory protein 1 sustains mitochondrial iron loading and function in frataxin deficiency.
Cell metabolism21(2)311-22(2015 Feb)
Martelli A,Schmucker S,Reutenauer L,Mathieu JR,Peyssonnaux C,Karim Z,Puy H,Galy B,Hentze MW,Puccio H

Transcription precedes loss of Xist coating and depletion of H3K27me3 during X-chromosome reprogramming in the mouse inner cell mass.
Development (Cambridge, England)138(10)2049-57(2011 May)
Williams LH,Kalantry S,Starmer J,Magnuson T

Dual mitochondrial localization and different roles of the reversible reaction of mammalian ferrochelatase.
The FEBS journal276(19)5559-70(2009 Oct)
Sakaino M,Ishigaki M,Ohgari Y,Kitajima S,Masaki R,Yamamoto A,Taketani S

Evidence of Xist RNA-independent initiation of mouse imprinted X-chromosome inactivation.
Nature460(7255)647-51(2009 Jul)
Kalantry S,Purushothaman S,Bowen RB,Starmer J,Magnuson T