The following Prex2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Prex2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu14219 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001033636.4 | |
| Accession Version | NM_001033636.4 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 405bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-19 | |
| Organism | Mus musculus(house mouse) | |
| Product | phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein isoform 2 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK136059.1, AC164600.5 and AI553603.1. On Apr 18, 2008 this sequence version replaced NM_001033636.3. Transcript Variant: This variant (2) uses a different segment for its 5' UTR and lacks much of the 5' coding region when compared to variant 1. The resulting protein (isoform 2) is much shorter when it is compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK136059.1, CO802244.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGAAGCCTC TCAATGCTTT AGATGAACTT TACCGGCTGA TCACCTCATT TATCAGATCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001028808.1 |
| CDS | 204..608 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001033636.4 |
1 | ATGAAGCCTC TCAATGCTTT AGATGAACTT TACCGGCTGA TCACCTCATT TATCAGATCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu27099 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006495441.4 , XM_006495441.3 | |
| Accession Version | XM_006495441.4 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 4854bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-08-07 | |
| Organism | Mus musculus(house mouse) | |
| Product | phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006495441.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGAGCGACG AAAGCGCCAG GGAAGTAGAC AAGCAGCTTC GCCTGCGCGT GTGCGTGCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006495504.1 |
| CDS | 521..5374 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006495441.4 |
1 | ATGAGCGACG AAAGCGCCAG GGAAGTAGAC AAGCAGCTTC GCCTGCGCGT GTGCGTGCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu14243 | |
| Clone ID Related Accession (Same CDS sequence) | NM_029525.1 | |
| Accession Version | NM_029525.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 4797bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-19 | |
| Organism | Mus musculus(house mouse) | |
| Product | phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein isoform 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK138884.1, AC102631.9, AC102481.10, AC164600.5 and AI553603.1. On Apr 19, 2008 this sequence version replaced XM_001475275.1. Transcript Variant: This variant (1) represents the longer variant and it encodes the longer protein (isoform 1). Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AM109952.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849382, SAMN00849387 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGAGCGACG AAAGCGCCAG GGAAGTAGAC AAGCAGCTTC GCCTGCGCGT GTGCGTGCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_083801.1 |
| CDS | 329..5125 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_029525.1 |
1 | ATGAGCGACG AAAGCGCCAG GGAAGTAGAC AAGCAGCTTC GCCTGCGCGT GTGCGTGCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu27099 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006495441.4 , XM_006495441.3 | |
| Accession Version | XM_006495441.3 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 4854bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-06-21 | |
| Organism | Mus musculus(house mouse) | |
| Product | phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000067.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006495441.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGAGCGACG AAAGCGCCAG GGAAGTAGAC AAGCAGCTTC GCCTGCGCGT GTGCGTGCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006495504.1 |
| CDS | 522..5375 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006495441.3 |
1 | ATGAGCGACG AAAGCGCCAG GGAAGTAGAC AAGCAGCTTC GCCTGCGCGT GTGCGTGCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Interplay between PREX2 mutations and the PI3K pathway and its effect on epigenetic regulation of gene expression in NRAS-mutant melanoma. |
Truncating PREX2 mutations activate its GEF activity and alter gene expression regulation in NRAS-mutant melanoma. |
PTEN inhibits PREX2-catalyzed activation of RAC1 to restrain tumor cell invasion. |
P-Rex and Vav Rac-GEFs in platelets control leukocyte recruitment to sites of inflammation. |
P-Rex1 directly activates RhoG to regulate GPCR-driven Rac signalling and actin polarity in neutrophils. |
