Rab31 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rab31
Entrez Gene ID	106572
Full Name	RAB31, member RAS oncogene family
Synonyms	1700093E07Rik,AI415285,Rab22B
General protein information	Preferred Names RAB31, member RAS oncogene family Names ras-related protein Rab-31
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 17 Map Location: 17\|17 E1.1

mRNA and Protein(s)

mRNA	Protein	Name
NM_133685.2	NP_598446.2	ras-related protein Rab-31

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	rab31	NP_001093711.1
Pan troglodytes (chimpanzee)	RAB31	XP_523865.3
Canis lupus familiaris (dog)	RAB31	XP_850610.2
Bos taurus (cattle)	RAB31	NP_001070412.1
Rattus norvegicus (Norway rat)	Rab31	NP_659562.2
Homo sapiens (human)	RAB31	NP_006859.2
Gallus gallus (chicken)	RAB31	XP_428301.4
Danio rerio (zebrafish)	LOC568800	XP_697248.2
	RAB31	XP_001096759.1
Mus musculus (house mouse)	Rab31	NP_598446.2

Gene Ontology
Bibliography

Related articles in PubMed

Post-transcriptional regulation of mouse neurogenesis by Pumilio proteins.
Zhang M, Chen D, Xia J, Han W, Cui X, Neuenkirchen N, Hermes G, Sestan N, Lin H
Genes & development(2017 Aug)

Rab31 and APPL2 enhance Fc?R-mediated phagocytosis through PI3K/Akt signaling in macrophages.
Yeo JC, Wall AA, Luo L, Stow JL
Molecular biology of the cell26(5)952-65(2015 Mar)

Rab31 is expressed in neural progenitor cells and plays a role in their differentiation.
Chua CE, Goh EL, Tang BL
FEBS letters588(17)3186-94(2014 Aug)

Engagement of the small GTPase Rab31 protein and its effector, early endosome antigen 1, is important for trafficking of the ligand-bound epidermal growth factor receptor from the early to the late endosome.
Chua CE, Tang BL
The Journal of biological chemistry289(18)12375-89(2014 May)

Single-step protease cleavage elution for identification of protein-protein interactions from GST pull-down and mass spectrometry.
Luo L, King NP, Yeo JC, Jones A, Stow JL
Proteomics14(1)19-23(2014 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Rab31, with APPL2 as its effector, play a role in FcgammaR-mediated phagocytosis through PI3K/Akt signaling in macrophages.
Title: Rab31 and APPL2 enhance Fc?R-mediated phagocytosis through PI3K/Akt signaling in macrophages.

a previously unrecognised role for Rab31 in influencing the differentiation and fate of neural progenitor cells
Title: Rab31 is expressed in neural progenitor cells and plays a role in their differentiation.

Rab22B is exceptionally enriched in nestin and RC2-positive radial glia of the embryonic mouse brain. In the adult brain, Rab22B is rather specifically expressed in glial fibrillary acidic protein (GFAP)-positive mature astrocytes.
Title: Rab22B is expressed in the CNS astroglia lineage and plays a role in epidermal growth factor receptor trafficking in A431 cells.

Insulin recruits the CIP4/Gapex-5 complex to the plasma membrane, thus reducing Rab31 activity and permitting Glut4 vesicles to translocate to the cell surface, where Glut4 docks and fuses to transport glucose into the cell.
Title: Gapex-5, a Rab31 guanine nucleotide exchange factor that regulates Glut4 trafficking in adipocytes.

The following Rab31 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rab31 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu10080	NM_133685.2 Latest version!	Mus musculus RAB31, member RAS oncogene family (Rab31), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rab31 ( NM_133685.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_598446.2 Mus musculus RAB31, member RAS oncogene family (Rab31), mRNA.

Price & Availability↑

CloneID	OMu10080
Clone ID Related Accession (Same CDS sequence)	NM_133685.2
Accession Version	NM_133685.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 588bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-20
Organism	Mus musculus(house mouse)
Product	ras-related protein Rab-31
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC139751.2, AK051270.1, AK159095.1, AC166058.2 and BY761495.1. On Mar 24, 2009 this sequence version replaced NM_133685.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK156677.1, BC013063.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849376, SAMN01164131 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATGGCGA TACGGGAGCT CAAAGTGTGT CTTCTCGGGG ACACGGGGGT TGGGAAATCC 
AGCATTGTGT GTCGTTTTGT CCAGGATCAC TTTGACCACA ACATCAGCCC CACTATTGGG 
GCATCTTTCA TGACCAAAAC CGTGCCTTGT GGAAATGAAC TTCACAAATT CCTCATCTGG 
GACACCGCTG GCCAGGAGCG GTTCCACTCC CTGGCTCCTA TGTACTACCG AGGATCTGCT 
GCAGCCGTCA TCGTCTATGA CATCACTAAG CAGGATTCAT TTCATACCTT GAAAAAATGG 
GTCAAGGAGC TGAAGGAGCA CGGCCCAGAA AACATTGTGA TGGCGATTGC TGGGAACAAG 
TGTGACCTCT CTGATATTAG GGAGGTGCCC CTGAAGGACG CTAAGGAGTA CGCTGAATCC 
ATAGGTGCCA TCGTGGTGGA GACCAGCGCG AAGAATGCCA TTAACATCGA GGAGCTCTTT 
CAAGGAATCA GCCGCCAGAT CCCACCCTTG GGCCCTCAGG AAAATGGAAA CAGCGGCGGG 
ATCAAGCTTG GGAATCAGAG CTTGCAAGCC AGCCGTCGGT GCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_598446.2
CDS	209..796
Translation	MMAIRELKVCLLGDTGVGKSSIVCRFVQDHFDHNISPTIGASFMTKTVPCGNELHKFLIWDTAGQERFHSLAPMYYRGSAAAVIVYDITKQDSFHTLKKWVKELKEHGPENIVMAIAGNKCDLSDIREVPLKDAKEYAESIGAIVVETSAKNAINIEELFQGISRQIPPLGPQENGNSGGIKLGNQSLQASRRCC

Target ORF information:

RefSeq Version	NM_133685.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus RAB31, member RAS oncogene family (Rab31), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_133685.2

ORF Insert Sequence:

ATGATGGCGA TACGGGAGCT CAAAGTGTGT CTTCTCGGGG ACACGGGGGT TGGGAAATCC 
AGCATTGTGT GTCGTTTTGT CCAGGATCAC TTTGACCACA ACATCAGCCC CACTATTGGG 
GCATCTTTCA TGACCAAAAC CGTGCCTTGT GGAAATGAAC TTCACAAATT CCTCATCTGG 
GACACCGCTG GCCAGGAGCG GTTCCACTCC CTGGCTCCTA TGTACTACCG AGGATCTGCT 
GCAGCCGTCA TCGTCTATGA CATCACTAAG CAGGATTCAT TTCATACCTT GAAAAAATGG 
GTCAAGGAGC TGAAGGAGCA CGGCCCAGAA AACATTGTGA TGGCGATTGC TGGGAACAAG 
TGTGACCTCT CTGATATTAG GGAGGTGCCC CTGAAGGACG CTAAGGAGTA CGCTGAATCC 
ATAGGTGCCA TCGTGGTGGA GACCAGCGCG AAGAATGCCA TTAACATCGA GGAGCTCTTT 
CAAGGAATCA GCCGCCAGAT CCCACCCTTG GGCCCTCAGG AAAATGGAAA CAGCGGCGGG 
ATCAAGCTTG GGAATCAGAG CTTGCAAGCC AGCCGTCGGT GCTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Post-transcriptional regulation of mouse neurogenesis by Pumilio proteins.
Genes & development(2017 Aug)
Zhang M,Chen D,Xia J,Han W,Cui X,Neuenkirchen N,Hermes G,Sestan N,Lin H

Rab31 and APPL2 enhance Fc?R-mediated phagocytosis through PI3K/Akt signaling in macrophages.
Molecular biology of the cell26(5)952-65(2015 Mar)
Yeo JC,Wall AA,Luo L,Stow JL

Rab31 is expressed in neural progenitor cells and plays a role in their differentiation.
FEBS letters588(17)3186-94(2014 Aug)
Chua CE,Goh EL,Tang BL

Engagement of the small GTPase Rab31 protein and its effector, early endosome antigen 1, is important for trafficking of the ligand-bound epidermal growth factor receptor from the early to the late endosome.
The Journal of biological chemistry289(18)12375-89(2014 May)
Chua CE,Tang BL

Single-step protease cleavage elution for identification of protein-protein interactions from GST pull-down and mass spectrometry.
Proteomics14(1)19-23(2014 Jan)
Luo L,King NP,Yeo JC,Jones A,Stow JL