PAN2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PAN2
Entrez Gene ID	9924
Full Name	PAN2 poly(A) specific ribonuclease subunit
Synonyms	USP52
General protein information	Preferred Names PAN2 poly(A) specific ribonuclease subunit Names PAN2-PAN3 deadenylation complex catalytic subunit PAN2 PAB-dependent poly(A)-specific ribonuclease subunit 2 PAB-dependent poly(A)-specific ribonuclease subunit PAN2 PAB1P-dependent poly(A)-nuclease PAB1P-dependent poly(A)-specific ribonuclease PABP-dependent poly(A) nuclease 2 PAN deadenylation complex catalytic subunit 2 PAN deadenylation complex subunit 2 PAN2 poly(A) specific ribonuclease subunit homolog PAN2 polyA specific ribonuclease subunit inactive ubiquitin carboxyl-terminal hydrolase 52 poly(A)-nuclease deadenylation complex subunit 2 ubiquitin specific peptidase 52 ubiquitin specific protease 52
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12q13.3
Summary	This gene encodes a deadenylase that functions as the catalytic subunit of the polyadenylate binding protein dependent poly(A) nuclease complex. The encoded protein is a magnesium dependent 3' to 5' exoribonuclease that is involved in the degradation of cytoplasmic mRNAs. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].
Disorder MIM:	617447

mRNA and Protein(s)

mRNA	Protein	Name
NM_014871.4	NP_055686.3	PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform 3
NM_001166279.1	NP_001159751.1	PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform 2
NM_001127460.2	NP_001120932.1	PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform 1
NM_014871.5	NP_055686.4	PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform 3
NM_001127460.3	NP_001120932.2	PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform 1
NM_001166279.2	NP_001159751.2	PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform 2

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Pan2	NP_001008862.1
Kluyveromyces lactis	KLLA0E18877g	XP_454804.1
Magnaporthe oryzae (rice blast fungus)	MGG_17449	XP_003718602.1
Neurospora crassa	NCU10733	XP_001728299.1
Pan troglodytes (chimpanzee)	LOC451995	XP_003952222.1
Saccharomyces cerevisiae (baker's yeast)	PAN2	NP_011421.1
	PAN2	XP_001114990.2
Canis lupus familiaris (dog)	PAN2	XP_531635.3
Danio rerio (zebrafish)	LOC792831	XP_001920000.4
Homo sapiens (human)	PAN2	NP_001159751.1
Bos taurus (cattle)	PAN2	NP_001073078.2
Gallus gallus (chicken)	PAN2	NP_001012972.1
Drosophila melanogaster (fruit fly)	CG8232	NP_610427.2
Schizosaccharomyces pombe (fission yeast)	ubp13	NP_593053.2
Xenopus tropicalis (tropical clawed frog)	pan2	XP_002934576.2
Mus musculus (house mouse)	Pan2	NP_598753.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010626	XP_310122.4
Eremothecium gossypii	AGOS_AFL055W	NP_985493.2

Gene Ontology
Bibliography

Related articles in PubMed

Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.
He M, Xu M, Zhang B, Liang J, Chen P, Lee JY, Johnson TA, Li H, Yang X, Dai J, Liang L, Gui L, Qi Q, Huang J, Li Y, Adair LS, Aung T, Cai Q, Cheng CY, Cho MC, Cho YS, Chu M, Cui B, Gao YT, Go MJ, Gu D, Gu W, Guo H, Hao Y, Hong J, Hu Z, Hu Y, Huang J, Hwang JY, Ikram MK, Jin G, Kang DH, Khor CC, Kim BJ, Kim HT, Kubo M, Lee J, Lee J, Lee NR, Li R, Li J, Liu J, Longe J, Lu W, Lu X, Miao X, Okada Y, Ong RT, Qiu G, Seielstad M, Sim X, Song H, Takeuchi F, Tanaka T, Taylor PR, Wang L, Wang W, Wang Y, Wu C, Wu Y, Xiang YB, Yamamoto K, Yang H, Liao M, Yokota M, Young T, Zhang X, Kato N, Wang QK, Zheng W, Hu FB, Lin D, Shen H, Teo YY, Mo Z, Wong TY, Lin X, Mohlke KL, Ning G, Tsunoda T, Han BG, Shu XO, Tai ES, Wu T, Qi L
Human molecular genetics24(6)1791-800(2015 Mar)

Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.
Cheng CY, Schache M, Ikram MK, Young TL, Guggenheim JA, Vitart V, MacGregor S, Verhoeven VJ, Barathi VA, Liao J, Hysi PG, Bailey-Wilson JE, St Pourcain B, Kemp JP, McMahon G, Timpson NJ, Evans DM, Montgomery GW, Mishra A, Wang YX, Wang JJ, Rochtchina E, Polasek O, Wright AF, Amin N, van Leeuwen EM, Wilson JF, Pennell CE, van Duijn CM, de Jong PT, Vingerling JR, Zhou X, Chen P, Li R, Tay WT, Zheng Y, Chew M, , Burdon KP, Craig JE, Iyengar SK, Igo RP Jr, Lass JH Jr, , Chew EY, Haller T, Mihailov E, Metspalu A, Wedenoja J, Simpson CL, Wojciechowski R, H?hn R, Mirshahi A, Zeller T, Pfeiffer N, Lackner KJ, , Bettecken T, Meitinger T, Oexle K, Pirastu M, Portas L, Nag A, Williams KM, Yonova-Doing E, Klein R, Klein BE, Hosseini SM, Paterson AD, , Makela KM, Lehtimaki T, Kahonen M, Raitakari O, Yoshimura N, Matsuda F, Chen LJ, Pang CP, Yip SP, Yap MK, Meguro A, Mizuki N, Inoko H, Foster PJ, Zhao JH, Vithana E, Tai ES, Fan Q, Xu L, Campbell H, Fleck B, Rudan I, Aung T, Hofman A, Uitterlinden AG, Bencic G, Khor CC, Forward H, P?rssinen O, Mitchell P, Rivadeneira F, Hewitt AW, Williams C, Oostra BA, Teo YY, Hammond CJ, Stambolian D, Mackey DA, Klaver CC, Wong TY, Saw SM, Baird PN
American journal of human genetics93(2)264-77(2013 Aug)

The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability.
Bett JS, Ibrahim AF, Garg AK, Kelly V, Pedrioli P, Rocha S, Hay RT
The Biochemical journal451(2)185-94(2013 Apr)

miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOT.
Fabian MR, Cieplak MK, Frank F, Morita M, Green J, Srikumar T, Nagar B, Yamamoto T, Raught B, Duchaine TF, Sonenberg N
Nature structural & molecular biology18(11)1211-7(2011 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

USP52 is a key component of P-bodies required to prevent HIF1A mRNA degradation
Title: The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability.

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.

Observational study of gene-disease association. (HuGE Navigator)
Title: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.

hPan2 and hPan3 have roles in mRNA decay and exhibit cytoplasmic co-localization
Title: Identification of a human cytoplasmic poly(A) nuclease complex stimulated by poly(A)-binding protein.

The following PAN2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PAN2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu108307	NM_001127460.3 Latest version!	Homo sapiens poly(A) specific ribonuclease subunit PAN2 (PAN2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00
OHu108308	NM_014871.5 Latest version!	Homo sapiens poly(A) specific ribonuclease subunit PAN2 (PAN2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00
OHu108410	NM_001166279.2 Latest version!	Homo sapiens poly(A) specific ribonuclease subunit PAN2 (PAN2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00
OHu16340	NM_001127460.2 Latest version!	Homo sapiens poly(A) specific ribonuclease subunit PAN2 (PAN2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$384.30 $549.00
OHu16345	NM_014871.4 Latest version!	Homo sapiens poly(A) specific ribonuclease subunit PAN2 (PAN2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$69.30 $99.00
OHu16348	NM_001166279.1 Latest version!	Homo sapiens poly(A) specific ribonuclease subunit PAN2 (PAN2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$384.30 $549.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PAN2 ( NM_001127460.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001120932.2 Homo sapiens poly(A) specific ribonuclease subunit PAN2 (PAN2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu108307
Clone ID Related Accession (Same CDS sequence)	NM_001127460.3
Accession Version	NM_001127460.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3609bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-08
Organism	Homo sapiens(human)
Product	PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC073896.41. On Jun 2, 2019 this sequence version replaced NM_001127460.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.14694.1, BC094885.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACTTTG AGGGTCTGGA CCCTGGACTG GCAGAATATG CCCCAGCCAT GCATTCTGCC 
CTGGACCCTG TCTTGGATGC CCACCTGAAC CCAAGTCTGC TACAGAATGT GGAGCTGGAC 
CCAGAGGGAG TGGCCTTGGA GGCTCTTCCC GTCCAGGAAT CAGTGCACAT AATGGAAGGT 
GTCTACTCTG AATTGCACAG CGTGGTGGCT GAAGTGGGTG TACCTGTTTC CGTCTCCCAC 
TTTGACTTGC ACGAGGAGAT GCTGTGGGTG GGGAGCCACG GGGGCCATGC CACTTCATTT 
TTTGGCCCAG CCTTGGAGCG CTACTCATCC TTTCAAGTCA ATGGCAGTGA TGATATTCGG 
CAGATCCAGA GCCTGGAGAA TGGTATCCTT TTTCTCACCA AGAACAACCT CAAGTATATG 
GCCCGTGGGG GCCTCATTAT ATTTGATTAC CTGCTGGATG AGAATGAGGA TATGCACAGT 
CTCCTACTGA CTGACAGCAG CACTCTACTC GTTGGTGGGC TGCAGAATCA CATAATAGAG 
ATTGATCTTA ACACTGTCCA GGAGACTCAG AAGTATGCAG TAGAGACGCC TGGAGTCACC 
ATCATGAGAC AGACAAATCG CTTCTTCTTC TGCGGCCACA CGTCTGGCAA GGTTTCCCTG 
AGAGACCTCC GTACTTTTAA GGTGGAACAT GAGTTTGATG CCTTCTCAGG AAGTCTGTCA 
GACTTTGATG TGCATGGCAA CCTGCTAGCT GCCTGTGGCT TCTCCAGCCG CCTCACTGGC 
CTGGCCTGCG ACCGTTTCCT CAAGGTGTAT GATTTGCGCA TGATGCGTGC CATCACACCA 
CTTCAAGTAC ATGTGGATCC TGCCTTCTTG CGCTTCATTC CTACATATAC TTCTCGTCTT 
GCTATCATCT CTCAGTCAGG GCAGTGCCAA TTCTGTGAAC CCACAGGCCT GGCCAACCCA 
GCCGATATCT TTCATGTGAA TCCTGTGGGG CCTCTGCTAA TGACATTTGA TGTGTCAGCC 
AGCAAGCAGG CTCTGGCCTT TGGGGATTCT GAGGGCTGTG TGCACCTCTG GACTGATTCC 
CCGGAGCCTT CCTTCAACCC CTACTCCCGT GAGACTGAGT TTGCTTTGCC GTGTCTCGTG 
GACTCACTGC CTCCTCTGGA CTGGAGCCAG GACCTGCTGC CTCTTTCCCT CATCCCTGTC 
CCACTCACCA CTGACACACT TCTCTCTGAT TGGCCTGCTG CCAACTCTGC TCCAGCTCCC 
AGGCGAGCAC CACCCGTGGA TGCAGAGATT CTGCGCACCA TGAAGAAGGT GGGCTTCATT 
GGCTATGCGC CCAATCCCCG CACCAGGCTG CGCAATCAGA TACCCTACAG ACTCAAGGAG 
TCAGACAGTG AATTTGACAG CTTCAGCCAG GTCACTGAGT CACCAGTAGG ACGAGAAGAG 
GAACCACATC TCCACATGGT TTCTAAGAAA TACCGCAAGG TGACCATCAA ATATTCCAAG 
CTAGGGCTGG AGGACTTTGA CTTCAAACAC TACAATAAGA CCTTGTTTGC TGGATTAGAG 
CCCCACATTC CCAACGCCTA CTGTAACTGC ATGATCCAGG TGCTCTATTT CCTGGAGCCT 
GTACGCTGTC TAATTCAAAA CCACCTTTGC CAGAAGGAGT TCTGTCTGGC ATGTGAGCTG 
GGCTTCCTGT TTCACATGTT GGACCTCTCT CGTGGTGACC CTTGCCAGGG CAATAATTTT 
CTTCGGGCAT TCCGTACTAT TCCTGAGGCC TCAGCCCTCG GTCTAATCCT GGCTGACTCA 
GATGAGGCCT CAGGCAAGGG CAATCTGGCC AGGCTCATTC AGAGGTGGAA TCGCTTCATT 
CTCACTCAAC TGCATCAAGA TATGCAGGAG CTGGAAATAC CACAGGCTTA TCGAGGTGCT 
GGAGGCAGCA GCTTTTGCTC ATCGGGGGAC TCTGTTATTG GGCAGCTCTT CAGCTGTGAG 
ATGGAGAACT GCAGCCTCTG CCGCTGTGGC AGTGAGACCG TGCGAGCCTC ATCCACTCTG 
CTTTTCACAC TCTCCTACCC TGATGGTAGC AAAAGTGATA AAACTGGGAA GAACTATGAC 
TTTGCTCAGG TGCTGAAGCG AAGCATCTGC CTGGACCAGA ATACACAGGC CTGGTGTGAC 
ACCTGTGAAA AGTACCAGCC CACGATTCAG ACCCGCAACA TCCGCCATCT GCCAGATATT 
CTTGTCATCA ATTGTGAGGT GAACAGCTCA AAAGAGGCTG ATTTCTGGAG AATGCAGGCT 
GAGGTTGCCT TCAAGATGGC AGTAAAGAAA CACGGTGGGG AAATCTCCAA GAACAAGGAA 
TTTGCTTTGG CTGATTGGAA GGAACTAGGG AGTCCAGAGG GTGTGCTGGT GTGTCCCTCC 
ATTGAGGAGT TGAAGAACGT CTGGCTTCCT TTCTCCATTC GCATGAAGAT GACCAAAAAC 
AAAGGGCTGG ATGTTTGCAA TTGGACTGAT GGGGATGAGA TGCAGTGGGG CCCAGCCAGG 
GCAGAGGAGG AGCATGGTGT CTATGTGTAT GACCTGATGG CTACTGTGGT ACACATCCTG 
GACTCACGCA CAGGGGGCAG CCTGGTGGCT CACATCAAAG TTGGAGAGAC CTACCACCAG 
CGCAAGGAGG GCGTTACTCA CCAGCAGTGG TATCTGTTCA ATGACTTTCT TATTGAACCT 
ATTGATAAGC ATGAAGCTGT GCAGTTTGAC ATGAATTGGA AAGTACCTGC AATCCTTTAT 
TATGTCAAAC GGAATCTCAA TTCCAGATAC AACCTGAACA TCAAGAACCC TATTGAGGCA 
AGTGTCTTGC TGGCTGAAGC CTCGCTGGCA CGGAAGCAGC GGAAAACACA TACTACCTTT 
ATTCCACTGA TGCTGAATGA GATGCCACAG ATTGGGGACC TGGTGGGTCT GGATGCTGAG 
TTTGTCACCC TTAATGAGGA GGAAGCAGAG TTACGCAGTG ATGGTACCAA GTCTACCATT 
AAACCAAGCC AGATGTCAGT AGCCAGGATT ACCTGTGTTC GGGGCCAGGG ACCCAATGAG 
GGTATCCCCT TCATTGATGA CTACATCTCT ACCCAGGAGC AGGTGGTGGA TTACTTGACT 
CAATACTCGG GTATAAAGCC TGGTGACCTC GATGCCAAAA TTTCCTCCAA GCACCTAACA 
ACTCTCAAGT CTACCTACTT AAAGCTTCGT TTTCTCATTG ACATTGGAGT CAAGTTTGTG 
GGTCATGGCC TGCAGAAGGA CTTCCGGGTC ATCAACCTGA TGGTGCCCAA GGACCAAGTC 
CTTGACACTG TCTACCTGTT CCATATGCCC CGAAAACGAA TGATTTCCCT GCGATTCCTT 
GCTTGGTACT TTCTGGACCT GAAGATTCAA GGGGAAACCC ATGACAGTAT TGAGGATGCC 
CGCACAGCCC TTCAGCTGTA CCGAAAGTAT CTGGAGCTAA GCAAAAATGG CACTGAGCCT 
GAGTCTTTCC ACAAGGTGCT CAAGGGTCTT TATGAGAAGG GCAGAAAGAT GGACTGGAAG 
GTGCCTGAGC CTGAGGGCCA AACAAGTCCC AAGAATGCAG CTGTCTTCTC CTCAGTGCTG 
GCGCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001120932.2
CDS	347..3955
Translation	MNFEGLDPGLAEYAPAMHSALDPVLDAHLNPSLLQNVELDPEGVALEALPVQESVHIMEGVYSELHSVVAEVGVPVSVSHFDLHEEMLWVGSHGGHATSFFGPALERYSSFQVNGSDDIRQIQSLENGILFLTKNNLKYMARGGLIIFDYLLDENEDMHSLLLTDSSTLLVGGLQNHIIEIDLNTVQETQKYAVETPGVTIMRQTNRFFFCGHTSGKVSLRDLRTFKVEHEFDAFSGSLSDFDVHGNLLAACGFSSRLTGLACDRFLKVYDLRMMRAITPLQVHVDPAFLRFIPTYTSRLAIISQSGQCQFCEPTGLANPADIFHVNPVGPLLMTFDVSASKQALAFGDSEGCVHLWTDSPEPSFNPYSRETEFALPCLVDSLPPLDWSQDLLPLSLIPVPLTTDTLLSDWPAANSAPAPRRAPPVDAEILRTMKKVGFIGYAPNPRTRLRNQIPYRLKESDSEFDSFSQVTESPVGREEEPHLHMVSKKYRKVTIKYSKLGLEDFDFKHYNKTLFAGLEPHIPNAYCNCMIQVLYFLEPVRCLIQNHLCQKEFCLACELGFLFHMLDLSRGDPCQGNNFLRAFRTIPEASALGLILADSDEASGKGNLARLIQRWNRFILTQLHQDMQELEIPQAYRGAGGSSFCSSGDSVIGQLFSCEMENCSLCRCGSETVRASSTLLFTLSYPDGSKSDKTGKNYDFAQVLKRSICLDQNTQAWCDTCEKYQPTIQTRNIRHLPDILVINCEVNSSKEADFWRMQAEVAFKMAVKKHGGEISKNKEFALADWKELGSPEGVLVCPSIEELKNVWLPFSIRMKMTKNKGLDVCNWTDGDEMQWGPARAEEEHGVYVYDLMATVVHILDSRTGGSLVAHIKVGETYHQRKEGVTHQQWYLFNDFLIEPIDKHEAVQFDMNWKVPAILYYVKRNLNSRYNLNIKNPIEASVLLAEASLARKQRKTHTTFIPLMLNEMPQIGDLVGLDAEFVTLNEEEAELRSDGTKSTIKPSQMSVARITCVRGQGPNEGIPFIDDYISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYLKLRFLIDIGVKFVGHGLQKDFRVINLMVPKDQVLDTVYLFHMPRKRMISLRFLAWYFLDLKIQGETHDSIEDARTALQLYRKYLELSKNGTEPESFHKVLKGLYEKGRKMDWKVPEPEGQTSPKNAAVFSSVLAL

Target ORF information:

RefSeq Version	NM_001127460.3
Organism	Homo sapiens(human)
Definition	Homo sapiens poly(A) specific ribonuclease subunit PAN2 (PAN2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001127460.3

ORF Insert Sequence:

ATGAACTTTG AGGGTCTGGA CCCTGGACTG GCAGAATATG CCCCAGCCAT GCATTCTGCC 
CTGGACCCTG TCTTGGATGC CCACCTGAAC CCAAGTCTGC TACAGAATGT GGAGCTGGAC 
CCAGAGGGAG TGGCCTTGGA GGCTCTTCCC GTCCAGGAAT CAGTGCACAT AATGGAAGGT 
GTCTACTCTG AATTGCACAG CGTGGTGGCT GAAGTGGGTG TACCTGTTTC CGTCTCCCAC 
TTTGACTTGC ACGAGGAGAT GCTGTGGGTG GGGAGCCACG GGGGCCATGC CACTTCATTT 
TTTGGCCCAG CCTTGGAGCG CTACTCATCC TTTCAAGTCA ATGGCAGTGA TGATATTCGG 
CAGATCCAGA GCCTGGAGAA TGGTATCCTT TTTCTCACCA AGAACAACCT CAAGTATATG 
GCCCGTGGGG GCCTCATTAT ATTTGATTAC CTGCTGGATG AGAATGAGGA TATGCACAGT 
CTCCTACTGA CTGACAGCAG CACTCTACTC GTTGGTGGGC TGCAGAATCA CATAATAGAG 
ATTGATCTTA ACACTGTCCA GGAGACTCAG AAGTATGCAG TAGAGACGCC TGGAGTCACC 
ATCATGAGAC AGACAAATCG CTTCTTCTTC TGCGGCCACA CGTCTGGCAA GGTTTCCCTG 
AGAGACCTCC GTACTTTTAA GGTGGAACAT GAGTTTGATG CCTTCTCAGG AAGTCTGTCA 
GACTTTGATG TGCATGGCAA CCTGCTAGCT GCCTGTGGCT TCTCCAGCCG CCTCACTGGC 
CTGGCCTGCG ACCGTTTCCT CAAGGTGTAT GATTTGCGCA TGATGCGTGC CATCACACCA 
CTTCAAGTAC ATGTGGATCC TGCCTTCTTG CGCTTCATTC CTACATATAC TTCTCGTCTT 
GCTATCATCT CTCAGTCAGG GCAGTGCCAA TTCTGTGAAC CCACAGGCCT GGCCAACCCA 
GCCGATATCT TTCATGTGAA TCCTGTGGGG CCTCTGCTAA TGACATTTGA TGTGTCAGCC 
AGCAAGCAGG CTCTGGCCTT TGGGGATTCT GAGGGCTGTG TGCACCTCTG GACTGATTCC 
CCGGAGCCTT CCTTCAACCC CTACTCCCGT GAGACTGAGT TTGCTTTGCC GTGTCTCGTG 
GACTCACTGC CTCCTCTGGA CTGGAGCCAG GACCTGCTGC CTCTTTCCCT CATCCCTGTC 
CCACTCACCA CTGACACACT TCTCTCTGAT TGGCCTGCTG CCAACTCTGC TCCAGCTCCC 
AGGCGAGCAC CACCCGTGGA TGCAGAGATT CTGCGCACCA TGAAGAAGGT GGGCTTCATT 
GGCTATGCGC CCAATCCCCG CACCAGGCTG CGCAATCAGA TACCCTACAG ACTCAAGGAG 
TCAGACAGTG AATTTGACAG CTTCAGCCAG GTCACTGAGT CACCAGTAGG ACGAGAAGAG 
GAACCACATC TCCACATGGT TTCTAAGAAA TACCGCAAGG TGACCATCAA ATATTCCAAG 
CTAGGGCTGG AGGACTTTGA CTTCAAACAC TACAATAAGA CCTTGTTTGC TGGATTAGAG 
CCCCACATTC CCAACGCCTA CTGTAACTGC ATGATCCAGG TGCTCTATTT CCTGGAGCCT 
GTACGCTGTC TAATTCAAAA CCACCTTTGC CAGAAGGAGT TCTGTCTGGC ATGTGAGCTG 
GGCTTCCTGT TTCACATGTT GGACCTCTCT CGTGGTGACC CTTGCCAGGG CAATAATTTT 
CTTCGGGCAT TCCGTACTAT TCCTGAGGCC TCAGCCCTCG GTCTAATCCT GGCTGACTCA 
GATGAGGCCT CAGGCAAGGG CAATCTGGCC AGGCTCATTC AGAGGTGGAA TCGCTTCATT 
CTCACTCAAC TGCATCAAGA TATGCAGGAG CTGGAAATAC CACAGGCTTA TCGAGGTGCT 
GGAGGCAGCA GCTTTTGCTC ATCGGGGGAC TCTGTTATTG GGCAGCTCTT CAGCTGTGAG 
ATGGAGAACT GCAGCCTCTG CCGCTGTGGC AGTGAGACCG TGCGAGCCTC ATCCACTCTG 
CTTTTCACAC TCTCCTACCC TGATGGTAGC AAAAGTGATA AAACTGGGAA GAACTATGAC 
TTTGCTCAGG TGCTGAAGCG AAGCATCTGC CTGGACCAGA ATACACAGGC CTGGTGTGAC 
ACCTGTGAAA AGTACCAGCC CACGATTCAG ACCCGCAACA TCCGCCATCT GCCAGATATT 
CTTGTCATCA ATTGTGAGGT GAACAGCTCA AAAGAGGCTG ATTTCTGGAG AATGCAGGCT 
GAGGTTGCCT TCAAGATGGC AGTAAAGAAA CACGGTGGGG AAATCTCCAA GAACAAGGAA 
TTTGCTTTGG CTGATTGGAA GGAACTAGGG AGTCCAGAGG GTGTGCTGGT GTGTCCCTCC 
ATTGAGGAGT TGAAGAACGT CTGGCTTCCT TTCTCCATTC GCATGAAGAT GACCAAAAAC 
AAAGGGCTGG ATGTTTGCAA TTGGACTGAT GGGGATGAGA TGCAGTGGGG CCCAGCCAGG 
GCAGAGGAGG AGCATGGTGT CTATGTGTAT GACCTGATGG CTACTGTGGT ACACATCCTG 
GACTCACGCA CAGGGGGCAG CCTGGTGGCT CACATCAAAG TTGGAGAGAC CTACCACCAG 
CGCAAGGAGG GCGTTACTCA CCAGCAGTGG TATCTGTTCA ATGACTTTCT TATTGAACCT 
ATTGATAAGC ATGAAGCTGT GCAGTTTGAC ATGAATTGGA AAGTACCTGC AATCCTTTAT 
TATGTCAAAC GGAATCTCAA TTCCAGATAC AACCTGAACA TCAAGAACCC TATTGAGGCA 
AGTGTCTTGC TGGCTGAAGC CTCGCTGGCA CGGAAGCAGC GGAAAACACA TACTACCTTT 
ATTCCACTGA TGCTGAATGA GATGCCACAG ATTGGGGACC TGGTGGGTCT GGATGCTGAG 
TTTGTCACCC TTAATGAGGA GGAAGCAGAG TTACGCAGTG ATGGTACCAA GTCTACCATT 
AAACCAAGCC AGATGTCAGT AGCCAGGATT ACCTGTGTTC GGGGCCAGGG ACCCAATGAG 
GGTATCCCCT TCATTGATGA CTACATCTCT ACCCAGGAGC AGGTGGTGGA TTACTTGACT 
CAATACTCGG GTATAAAGCC TGGTGACCTC GATGCCAAAA TTTCCTCCAA GCACCTAACA 
ACTCTCAAGT CTACCTACTT AAAGCTTCGT TTTCTCATTG ACATTGGAGT CAAGTTTGTG 
GGTCATGGCC TGCAGAAGGA CTTCCGGGTC ATCAACCTGA TGGTGCCCAA GGACCAAGTC 
CTTGACACTG TCTACCTGTT CCATATGCCC CGAAAACGAA TGATTTCCCT GCGATTCCTT 
GCTTGGTACT TTCTGGACCT GAAGATTCAA GGGGAAACCC ATGACAGTAT TGAGGATGCC 
CGCACAGCCC TTCAGCTGTA CCGAAAGTAT CTGGAGCTAA GCAAAAATGG CACTGAGCCT 
GAGTCTTTCC ACAAGGTGCT CAAGGGTCTT TATGAGAAGG GCAGAAAGAT GGACTGGAAG 
GTGCCTGAGC CTGAGGGCCA AACAAGTCCC AAGAATGCAG CTGTCTTCTC CTCAGTGCTG 
GCGCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PAN2 ( NM_014871.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_055686.4 Homo sapiens poly(A) specific ribonuclease subunit PAN2 (PAN2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu108308
Clone ID Related Accession (Same CDS sequence)	NM_014871.5
Accession Version	NM_014871.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3597bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-08
Organism	Homo sapiens(human)
Product	PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC025574.19 and AC073896.41. On Jun 2, 2019 this sequence version replaced NM_014871.4. Transcript Variant: This variant (3) uses an alternate in-frame splice site in the coding region, compared to variant 1. The encoded isoform (3) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC024043.1, SRR1803616.180738.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAACTTTG AGGGTCTGGA CCCTGGACTG GCAGAATATG CCCCAGCCAT GCATTCTGCC 
CTGGACCCTG TCTTGGATGC CCACCTGAAC CCAAGTCTGC TACAGAATGT GGAGCTGGAC 
CCAGAGGGAG TGGCCTTGGA GGCTCTTCCC GTCCAGGAAT CAGTGCACAT AATGGAAGGT 
GTCTACTCTG AATTGCACAG CGTGGTGGCT GAAGTGGGTG TACCTGTTTC CGTCTCCCAC 
TTTGACTTGC ACGAGGAGAT GCTGTGGGTG GGGAGCCACG GGGGCCATGC CACTTCATTT 
TTTGGCCCAG CCTTGGAGCG CTACTCATCC TTTCAAGTCA ATGGCAGTGA TGATATTCGG 
CAGATCCAGA GCCTGGAGAA TGGTATCCTT TTTCTCACCA AGAACAACCT CAAGTATATG 
GCCCGTGGGG GCCTCATTAT ATTTGATTAC CTGCTGGATG AGAATGAGGA TATGCACAGT 
CTCCTACTGA CTGACAGCAG CACTCTACTC GTTGGTGGGC TGCAGAATCA CATAATAGAG 
ATTGATCTTA ACACTGTCCA GGAGACTCAG AAGTATGCAG TAGAGACGCC TGGAGTCACC 
ATCATGAGAC AGACAAATCG CTTCTTCTTC TGCGGCCACA CGTCTGGCAA GGTTTCCCTG 
AGAGACCTCC GTACTTTTAA GGTGGAACAT GAGTTTGATG CCTTCTCAGG AAGTCTGTCA 
GACTTTGATG TGCATGGCAA CCTGCTAGCT GCCTGTGGCT TCTCCAGCCG CCTCACTGGC 
CTGGCCTGCG ACCGTTTCCT CAAGGTGTAT GATTTGCGCA TGATGCGTGC CATCACACCA 
CTTCAAGTAC ATGTGGATCC TGCCTTCTTG CGCTTCATTC CTACATATAC TTCTCGTCTT 
GCTATCATCT CTCAGTCAGG GCAGTGCCAA TTCTGTGAAC CCACAGGCCT GGCCAACCCA 
GCCGATATCT TTCATGTGAA TCCTGTGGGG CCTCTGCTAA TGACATTTGA TGTGTCAGCC 
AGCAAGCAGG CTCTGGCCTT TGGGGATTCT GAGGGCTGTG TGCACCTCTG GACTGATTCC 
CCGGAGCCTT CCTTCAACCC CTACTCCCGT GAGACTGAGT TTGCTTTGCC GTGTCTCGTG 
GACTCACTGC CTCCTCTGGA CTGGAGCCAG GACCTGCTGC CTCTTTCCCT CATCCCTGTC 
CCACTCACCA CTGACACACT TCTCTCTGAT TGGCCTGCTG CCAACTCTGC TCCAGCTCCC 
AGGCGAGCAC CACCCGTGGA TGCAGAGATT CTGCGCACCA TGAAGAAGGT GGGCTTCATT 
GGCTATGCGC CCAATCCCCG CACCAGGCTG CGCAATCAGA TACCCTACAG ACTCAAGGAG 
TCAGACAGTG AATTTGACAG CTTCAGCCAG GTCACTGAGT CACCAGTAGG ACGAGAAGAG 
GAACCACATC TCCACATGGT TTCTAAGAAA TACCGCAAGG TGACCATCAA ATATTCCAAG 
CTAGGGCTGG AGGACTTTGA CTTCAAACAC TACAATAAGA CCTTGTTTGC TGGATTAGAG 
CCCCACATTC CCAACGCCTA CTGTAACTGC ATGATCCAGG TGCTCTATTT CCTGGAGCCT 
GTACGCTGTC TAATTCAAAA CCACCTTTGC CAGAAGGAGT TCTGTCTGGC ATGTGAGCTG 
GGCTTCCTGT TTCACATGTT GGACCTCTCT CGTGGTGACC CTTGCCAGGG CAATAATTTT 
CTTCGGGCAT TCCGTACTAT TCCTGAGGCC TCAGCCCTCG GTCTAATCCT GGCTGACTCA 
GATGAGGCCT CAGGCAAGGG CAATCTGGCC AGGCTCATTC AGAGGTGGAA TCGCTTCATT 
CTCACTCAAC TGCATCAAGA TATGCAGGAG CTGGAAATAC CACAGGCTTA TCGAGGTGCT 
GGAGGCAGCA GCTTTTGCTC ATCGGGGGAC TCTGTTATTG GGCAGCTCTT CAGCTGTGAG 
ATGGAGAACT GCAGCCTCTG CCGCTGTGGC AGTGAGACCG TGCGAGCCTC ATCCACTCTG 
CTTTTCACAC TCTCCTACCC TGATGATAAA ACTGGGAAGA ACTATGACTT TGCTCAGGTG 
CTGAAGCGAA GCATCTGCCT GGACCAGAAT ACACAGGCCT GGTGTGACAC CTGTGAAAAG 
TACCAGCCCA CGATTCAGAC CCGCAACATC CGCCATCTGC CAGATATTCT TGTCATCAAT 
TGTGAGGTGA ACAGCTCAAA AGAGGCTGAT TTCTGGAGAA TGCAGGCTGA GGTTGCCTTC 
AAGATGGCAG TAAAGAAACA CGGTGGGGAA ATCTCCAAGA ACAAGGAATT TGCTTTGGCT 
GATTGGAAGG AACTAGGGAG TCCAGAGGGT GTGCTGGTGT GTCCCTCCAT TGAGGAGTTG 
AAGAACGTCT GGCTTCCTTT CTCCATTCGC ATGAAGATGA CCAAAAACAA AGGGCTGGAT 
GTTTGCAATT GGACTGATGG GGATGAGATG CAGTGGGGCC CAGCCAGGGC AGAGGAGGAG 
CATGGTGTCT ATGTGTATGA CCTGATGGCT ACTGTGGTAC ACATCCTGGA CTCACGCACA 
GGGGGCAGCC TGGTGGCTCA CATCAAAGTT GGAGAGACCT ACCACCAGCG CAAGGAGGGC 
GTTACTCACC AGCAGTGGTA TCTGTTCAAT GACTTTCTTA TTGAACCTAT TGATAAGCAT 
GAAGCTGTGC AGTTTGACAT GAATTGGAAA GTACCTGCAA TCCTTTATTA TGTCAAACGG 
AATCTCAATT CCAGATACAA CCTGAACATC AAGAACCCTA TTGAGGCAAG TGTCTTGCTG 
GCTGAAGCCT CGCTGGCACG GAAGCAGCGG AAAACACATA CTACCTTTAT TCCACTGATG 
CTGAATGAGA TGCCACAGAT TGGGGACCTG GTGGGTCTGG ATGCTGAGTT TGTCACCCTT 
AATGAGGAGG AAGCAGAGTT ACGCAGTGAT GGTACCAAGT CTACCATTAA ACCAAGCCAG 
ATGTCAGTAG CCAGGATTAC CTGTGTTCGG GGCCAGGGAC CCAATGAGGG TATCCCCTTC 
ATTGATGACT ACATCTCTAC CCAGGAGCAG GTGGTGGATT ACTTGACTCA ATACTCGGGT 
ATAAAGCCTG GTGACCTCGA TGCCAAAATT TCCTCCAAGC ACCTAACAAC TCTCAAGTCT 
ACCTACTTAA AGCTTCGTTT TCTCATTGAC ATTGGAGTCA AGTTTGTGGG TCATGGCCTG 
CAGAAGGACT TCCGGGTCAT CAACCTGATG GTGCCCAAGG ACCAAGTCCT TGACACTGTC 
TACCTGTTCC ATATGCCCCG AAAACGAATG ATTTCCCTGC GATTCCTTGC TTGGTACTTT 
CTGGACCTGA AGATTCAAGG GGAAACCCAT GACAGTATTG AGGATGCCCG CACAGCCCTT 
CAGCTGTACC GAAAGTATCT GGAGCTAAGC AAAAATGGCA CTGAGCCTGA GTCTTTCCAC 
AAGGTGCTCA AGGGTCTTTA TGAGAAGGGC AGAAAGATGG ACTGGAAGGT GCCTGAGCCT 
GAGGGCCAAA CAAGTCCCAA GAATGCAGCT GTCTTCTCCT CAGTGCTGGC GCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055686.4
CDS	254..3850
Translation	MNFEGLDPGLAEYAPAMHSALDPVLDAHLNPSLLQNVELDPEGVALEALPVQESVHIMEGVYSELHSVVAEVGVPVSVSHFDLHEEMLWVGSHGGHATSFFGPALERYSSFQVNGSDDIRQIQSLENGILFLTKNNLKYMARGGLIIFDYLLDENEDMHSLLLTDSSTLLVGGLQNHIIEIDLNTVQETQKYAVETPGVTIMRQTNRFFFCGHTSGKVSLRDLRTFKVEHEFDAFSGSLSDFDVHGNLLAACGFSSRLTGLACDRFLKVYDLRMMRAITPLQVHVDPAFLRFIPTYTSRLAIISQSGQCQFCEPTGLANPADIFHVNPVGPLLMTFDVSASKQALAFGDSEGCVHLWTDSPEPSFNPYSRETEFALPCLVDSLPPLDWSQDLLPLSLIPVPLTTDTLLSDWPAANSAPAPRRAPPVDAEILRTMKKVGFIGYAPNPRTRLRNQIPYRLKESDSEFDSFSQVTESPVGREEEPHLHMVSKKYRKVTIKYSKLGLEDFDFKHYNKTLFAGLEPHIPNAYCNCMIQVLYFLEPVRCLIQNHLCQKEFCLACELGFLFHMLDLSRGDPCQGNNFLRAFRTIPEASALGLILADSDEASGKGNLARLIQRWNRFILTQLHQDMQELEIPQAYRGAGGSSFCSSGDSVIGQLFSCEMENCSLCRCGSETVRASSTLLFTLSYPDDKTGKNYDFAQVLKRSICLDQNTQAWCDTCEKYQPTIQTRNIRHLPDILVINCEVNSSKEADFWRMQAEVAFKMAVKKHGGEISKNKEFALADWKELGSPEGVLVCPSIEELKNVWLPFSIRMKMTKNKGLDVCNWTDGDEMQWGPARAEEEHGVYVYDLMATVVHILDSRTGGSLVAHIKVGETYHQRKEGVTHQQWYLFNDFLIEPIDKHEAVQFDMNWKVPAILYYVKRNLNSRYNLNIKNPIEASVLLAEASLARKQRKTHTTFIPLMLNEMPQIGDLVGLDAEFVTLNEEEAELRSDGTKSTIKPSQMSVARITCVRGQGPNEGIPFIDDYISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYLKLRFLIDIGVKFVGHGLQKDFRVINLMVPKDQVLDTVYLFHMPRKRMISLRFLAWYFLDLKIQGETHDSIEDARTALQLYRKYLELSKNGTEPESFHKVLKGLYEKGRKMDWKVPEPEGQTSPKNAAVFSSVLAL

Target ORF information:

RefSeq Version	NM_014871.5
Organism	Homo sapiens(human)
Definition	Homo sapiens poly(A) specific ribonuclease subunit PAN2 (PAN2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014871.5

ORF Insert Sequence:

ATGAACTTTG AGGGTCTGGA CCCTGGACTG GCAGAATATG CCCCAGCCAT GCATTCTGCC 
CTGGACCCTG TCTTGGATGC CCACCTGAAC CCAAGTCTGC TACAGAATGT GGAGCTGGAC 
CCAGAGGGAG TGGCCTTGGA GGCTCTTCCC GTCCAGGAAT CAGTGCACAT AATGGAAGGT 
GTCTACTCTG AATTGCACAG CGTGGTGGCT GAAGTGGGTG TACCTGTTTC CGTCTCCCAC 
TTTGACTTGC ACGAGGAGAT GCTGTGGGTG GGGAGCCACG GGGGCCATGC CACTTCATTT 
TTTGGCCCAG CCTTGGAGCG CTACTCATCC TTTCAAGTCA ATGGCAGTGA TGATATTCGG 
CAGATCCAGA GCCTGGAGAA TGGTATCCTT TTTCTCACCA AGAACAACCT CAAGTATATG 
GCCCGTGGGG GCCTCATTAT ATTTGATTAC CTGCTGGATG AGAATGAGGA TATGCACAGT 
CTCCTACTGA CTGACAGCAG CACTCTACTC GTTGGTGGGC TGCAGAATCA CATAATAGAG 
ATTGATCTTA ACACTGTCCA GGAGACTCAG AAGTATGCAG TAGAGACGCC TGGAGTCACC 
ATCATGAGAC AGACAAATCG CTTCTTCTTC TGCGGCCACA CGTCTGGCAA GGTTTCCCTG 
AGAGACCTCC GTACTTTTAA GGTGGAACAT GAGTTTGATG CCTTCTCAGG AAGTCTGTCA 
GACTTTGATG TGCATGGCAA CCTGCTAGCT GCCTGTGGCT TCTCCAGCCG CCTCACTGGC 
CTGGCCTGCG ACCGTTTCCT CAAGGTGTAT GATTTGCGCA TGATGCGTGC CATCACACCA 
CTTCAAGTAC ATGTGGATCC TGCCTTCTTG CGCTTCATTC CTACATATAC TTCTCGTCTT 
GCTATCATCT CTCAGTCAGG GCAGTGCCAA TTCTGTGAAC CCACAGGCCT GGCCAACCCA 
GCCGATATCT TTCATGTGAA TCCTGTGGGG CCTCTGCTAA TGACATTTGA TGTGTCAGCC 
AGCAAGCAGG CTCTGGCCTT TGGGGATTCT GAGGGCTGTG TGCACCTCTG GACTGATTCC 
CCGGAGCCTT CCTTCAACCC CTACTCCCGT GAGACTGAGT TTGCTTTGCC GTGTCTCGTG 
GACTCACTGC CTCCTCTGGA CTGGAGCCAG GACCTGCTGC CTCTTTCCCT CATCCCTGTC 
CCACTCACCA CTGACACACT TCTCTCTGAT TGGCCTGCTG CCAACTCTGC TCCAGCTCCC 
AGGCGAGCAC CACCCGTGGA TGCAGAGATT CTGCGCACCA TGAAGAAGGT GGGCTTCATT 
GGCTATGCGC CCAATCCCCG CACCAGGCTG CGCAATCAGA TACCCTACAG ACTCAAGGAG 
TCAGACAGTG AATTTGACAG CTTCAGCCAG GTCACTGAGT CACCAGTAGG ACGAGAAGAG 
GAACCACATC TCCACATGGT TTCTAAGAAA TACCGCAAGG TGACCATCAA ATATTCCAAG 
CTAGGGCTGG AGGACTTTGA CTTCAAACAC TACAATAAGA CCTTGTTTGC TGGATTAGAG 
CCCCACATTC CCAACGCCTA CTGTAACTGC ATGATCCAGG TGCTCTATTT CCTGGAGCCT 
GTACGCTGTC TAATTCAAAA CCACCTTTGC CAGAAGGAGT TCTGTCTGGC ATGTGAGCTG 
GGCTTCCTGT TTCACATGTT GGACCTCTCT CGTGGTGACC CTTGCCAGGG CAATAATTTT 
CTTCGGGCAT TCCGTACTAT TCCTGAGGCC TCAGCCCTCG GTCTAATCCT GGCTGACTCA 
GATGAGGCCT CAGGCAAGGG CAATCTGGCC AGGCTCATTC AGAGGTGGAA TCGCTTCATT 
CTCACTCAAC TGCATCAAGA TATGCAGGAG CTGGAAATAC CACAGGCTTA TCGAGGTGCT 
GGAGGCAGCA GCTTTTGCTC ATCGGGGGAC TCTGTTATTG GGCAGCTCTT CAGCTGTGAG 
ATGGAGAACT GCAGCCTCTG CCGCTGTGGC AGTGAGACCG TGCGAGCCTC ATCCACTCTG 
CTTTTCACAC TCTCCTACCC TGATGATAAA ACTGGGAAGA ACTATGACTT TGCTCAGGTG 
CTGAAGCGAA GCATCTGCCT GGACCAGAAT ACACAGGCCT GGTGTGACAC CTGTGAAAAG 
TACCAGCCCA CGATTCAGAC CCGCAACATC CGCCATCTGC CAGATATTCT TGTCATCAAT 
TGTGAGGTGA ACAGCTCAAA AGAGGCTGAT TTCTGGAGAA TGCAGGCTGA GGTTGCCTTC 
AAGATGGCAG TAAAGAAACA CGGTGGGGAA ATCTCCAAGA ACAAGGAATT TGCTTTGGCT 
GATTGGAAGG AACTAGGGAG TCCAGAGGGT GTGCTGGTGT GTCCCTCCAT TGAGGAGTTG 
AAGAACGTCT GGCTTCCTTT CTCCATTCGC ATGAAGATGA CCAAAAACAA AGGGCTGGAT 
GTTTGCAATT GGACTGATGG GGATGAGATG CAGTGGGGCC CAGCCAGGGC AGAGGAGGAG 
CATGGTGTCT ATGTGTATGA CCTGATGGCT ACTGTGGTAC ACATCCTGGA CTCACGCACA 
GGGGGCAGCC TGGTGGCTCA CATCAAAGTT GGAGAGACCT ACCACCAGCG CAAGGAGGGC 
GTTACTCACC AGCAGTGGTA TCTGTTCAAT GACTTTCTTA TTGAACCTAT TGATAAGCAT 
GAAGCTGTGC AGTTTGACAT GAATTGGAAA GTACCTGCAA TCCTTTATTA TGTCAAACGG 
AATCTCAATT CCAGATACAA CCTGAACATC AAGAACCCTA TTGAGGCAAG TGTCTTGCTG 
GCTGAAGCCT CGCTGGCACG GAAGCAGCGG AAAACACATA CTACCTTTAT TCCACTGATG 
CTGAATGAGA TGCCACAGAT TGGGGACCTG GTGGGTCTGG ATGCTGAGTT TGTCACCCTT 
AATGAGGAGG AAGCAGAGTT ACGCAGTGAT GGTACCAAGT CTACCATTAA ACCAAGCCAG 
ATGTCAGTAG CCAGGATTAC CTGTGTTCGG GGCCAGGGAC CCAATGAGGG TATCCCCTTC 
ATTGATGACT ACATCTCTAC CCAGGAGCAG GTGGTGGATT ACTTGACTCA ATACTCGGGT 
ATAAAGCCTG GTGACCTCGA TGCCAAAATT TCCTCCAAGC ACCTAACAAC TCTCAAGTCT 
ACCTACTTAA AGCTTCGTTT TCTCATTGAC ATTGGAGTCA AGTTTGTGGG TCATGGCCTG 
CAGAAGGACT TCCGGGTCAT CAACCTGATG GTGCCCAAGG ACCAAGTCCT TGACACTGTC 
TACCTGTTCC ATATGCCCCG AAAACGAATG ATTTCCCTGC GATTCCTTGC TTGGTACTTT 
CTGGACCTGA AGATTCAAGG GGAAACCCAT GACAGTATTG AGGATGCCCG CACAGCCCTT 
CAGCTGTACC GAAAGTATCT GGAGCTAAGC AAAAATGGCA CTGAGCCTGA GTCTTTCCAC 
AAGGTGCTCA AGGGTCTTTA TGAGAAGGGC AGAAAGATGG ACTGGAAGGT GCCTGAGCCT 
GAGGGCCAAA CAAGTCCCAA GAATGCAGCT GTCTTCTCCT CAGTGCTGGC GCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PAN2 ( NM_001166279.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001159751.2 Homo sapiens poly(A) specific ribonuclease subunit PAN2 (PAN2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu108410
Clone ID Related Accession (Same CDS sequence)	NM_001166279.2
Accession Version	NM_001166279.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3606bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Homo sapiens(human)
Product	PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC025574.19 and AC073896.41. On Jun 2, 2019 this sequence version replaced NM_001166279.1. Transcript Variant: This variant (2) differs in the 5' UTR and coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB014610.2, SRR1803616.241356.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACTTTG AGGGTCTGGA CCCTGGACTG GCAGAATATG CCCCAGCCAT GCATTCTGCC 
CTGGACCCTG TCTTGGATGC CCACCTGAAC CCAAGTCTGC TACAGAATGT GGAGCTGGAC 
CCAGAGGGAG TGGCCTTGGA GGCTCTTCCC GTCCAGGAAT CAGTGCACAT AATGGAAGGT 
GTCTACTCTG AATTGCACAG CGTGGTGGCT GAAGTGGGTG TACCTGTTTC CGTCTCCCAC 
TTTGACTTGC ACGAGGAGAT GCTGTGGGTG GGGAGCCACG GGGGCCATGC CACTTCATTT 
TTTGGCCCAG CCTTGGAGCG CTACTCATCC TTTCAAGTCA ATGGCAGTGA TGATATTCGG 
CAGATCCAGA GCCTGGAGAA TGGTATCCTT TTTCTCACCA AGAACAACCT CAAGTATATG 
GCCCGTGGGG GCCTCATTAT ATTTGATTAC CTGCTGGATG AGAATGAGGA TATGCACAGT 
CTCCTACTGA CTGACAGCAG CACTCTACTC GTTGGTGGGC TGCAGAATCA CATAATAGAG 
ATTGATCTTA ACACTGTCCA GGAGACTCAG AAGTATGCAG TAGAGACGCC TGGAGTCACC 
ATCATGAGAC AGACAAATCG CTTCTTCTTC TGCGGCCACA CGTCTGGCAA GGTTTCCCTG 
AGAGACCTCC GTACTTTTAA GGTGGAACAT GAGTTTGATG CCTTCTCAGG AAGTCTGTCA 
GACTTTGATG TGCATGGCAA CCTGCTAGCT GCCTGTGGCT TCTCCAGCCG CCTCACTGGC 
CTGGCCTGCG ACCGTTTCCT CAAGGTGTAT GATTTGCGCA TGATGCGTGC CATCACACCA 
CTTCAAGTAC ATGTGGATCC TGCCTTCTTG CGCTTCATTC CTACATATAC TTCTCGTCTT 
GCTATCATCT CTCAGTCAGG GCAGTGCCAA TTCTGTGAAC CCACAGGCCT GGCCAACCCA 
GCCGATATCT TTCATGTGAA TCCTGTGGGG CCTCTGCTAA TGACATTTGA TGTGTCAGCC 
AGCAAGCAGG CTCTGGCCTT TGGGGATTCT GAGGGCTGTG TGCACCTCTG GACTGATTCC 
CCGGAGCCTT CCTTCAACCC CTACTCCCGT GAGACTGAGT TTGCTTTGCC GTGTCTCGTG 
GACTCACTGC CTCCTCTGGA CTGGAGCCAG GACCTGCTGC CTCTTTCCCT CATCCCTGTC 
CCACTCACCA CTGACACACT TCTCTCTGAT TGGCCTGCTG CCAACTCTGC TCCAGCTCCC 
AGGCGAGCAC CACCCGTGGA TGCAGAGATT CTGCGCACCA TGAAGAAGGT GGGCTTCATT 
GGCTATGCGC CCAATCCCCG CACCAGGCTG CGCAATCAGA TACCCTACAG ACTCAAGGAG 
TCAGACAGTG AATTTGACAG CTTCAGCCAG GTCACTGAGT CACCAGTAGG ACGAGAAGAG 
GAACCACATC TCCACATGGT TTCTAAGAAA TACCGCAAGG TGACCATCAA ATATTCCAAG 
CTAGGGCTGG AGGACTTTGA CTTCAAACAC TACAATAAGA CCTTGTTTGC TGGATTAGAG 
CCCCACATTC CCAACGCCTA CTGTAACTGC ATGATCCAGG TGCTCTATTT CCTGGAGCCT 
GTACGCTGTC TAATTCAAAA CCACCTTTGC CAGAAGGAGT TCTGTCTGGC ATGTGAGCTG 
GGCTTCCTGT TTCACATGTT GGACCTCTCT CGTGGTGACC CTTGCCAGGG CAATAATTTT 
CTTCGGGCAT TCCGTACTAT TCCTGAGGCC TCAGCCCTCG GTCTAATCCT GGCTGACTCA 
GATGAGGCCT CAGGCAAGGG CAATCTGGCC AGGCTCATTC AGAGGTGGAA TCGCTTCATT 
CTCACTCAAC TGCATCAAGA TATGCAGGAG CTGGAAATAC CACAGGCTTA TCGAGGTGCT 
GGAGGCAGCT TTTGCTCATC GGGGGACTCT GTTATTGGGC AGCTCTTCAG CTGTGAGATG 
GAGAACTGCA GCCTCTGCCG CTGTGGCAGT GAGACCGTGC GAGCCTCATC CACTCTGCTT 
TTCACACTCT CCTACCCTGA TGGTAGCAAA AGTGATAAAA CTGGGAAGAA CTATGACTTT 
GCTCAGGTGC TGAAGCGAAG CATCTGCCTG GACCAGAATA CACAGGCCTG GTGTGACACC 
TGTGAAAAGT ACCAGCCCAC GATTCAGACC CGCAACATCC GCCATCTGCC AGATATTCTT 
GTCATCAATT GTGAGGTGAA CAGCTCAAAA GAGGCTGATT TCTGGAGAAT GCAGGCTGAG 
GTTGCCTTCA AGATGGCAGT AAAGAAACAC GGTGGGGAAA TCTCCAAGAA CAAGGAATTT 
GCTTTGGCTG ATTGGAAGGA ACTAGGGAGT CCAGAGGGTG TGCTGGTGTG TCCCTCCATT 
GAGGAGTTGA AGAACGTCTG GCTTCCTTTC TCCATTCGCA TGAAGATGAC CAAAAACAAA 
GGGCTGGATG TTTGCAATTG GACTGATGGG GATGAGATGC AGTGGGGCCC AGCCAGGGCA 
GAGGAGGAGC ATGGTGTCTA TGTGTATGAC CTGATGGCTA CTGTGGTACA CATCCTGGAC 
TCACGCACAG GGGGCAGCCT GGTGGCTCAC ATCAAAGTTG GAGAGACCTA CCACCAGCGC 
AAGGAGGGCG TTACTCACCA GCAGTGGTAT CTGTTCAATG ACTTTCTTAT TGAACCTATT 
GATAAGCATG AAGCTGTGCA GTTTGACATG AATTGGAAAG TACCTGCAAT CCTTTATTAT 
GTCAAACGGA ATCTCAATTC CAGATACAAC CTGAACATCA AGAACCCTAT TGAGGCAAGT 
GTCTTGCTGG CTGAAGCCTC GCTGGCACGG AAGCAGCGGA AAACACATAC TACCTTTATT 
CCACTGATGC TGAATGAGAT GCCACAGATT GGGGACCTGG TGGGTCTGGA TGCTGAGTTT 
GTCACCCTTA ATGAGGAGGA AGCAGAGTTA CGCAGTGATG GTACCAAGTC TACCATTAAA 
CCAAGCCAGA TGTCAGTAGC CAGGATTACC TGTGTTCGGG GCCAGGGACC CAATGAGGGT 
ATCCCCTTCA TTGATGACTA CATCTCTACC CAGGAGCAGG TGGTGGATTA CTTGACTCAA 
TACTCGGGTA TAAAGCCTGG TGACCTCGAT GCCAAAATTT CCTCCAAGCA CCTAACAACT 
CTCAAGTCTA CCTACTTAAA GCTTCGTTTT CTCATTGACA TTGGAGTCAA GTTTGTGGGT 
CATGGCCTGC AGAAGGACTT CCGGGTCATC AACCTGATGG TGCCCAAGGA CCAAGTCCTT 
GACACTGTCT ACCTGTTCCA TATGCCCCGA AAACGAATGA TTTCCCTGCG ATTCCTTGCT 
TGGTACTTTC TGGACCTGAA GATTCAAGGG GAAACCCATG ACAGTATTGA GGATGCCCGC 
ACAGCCCTTC AGCTGTACCG AAAGTATCTG GAGCTAAGCA AAAATGGCAC TGAGCCTGAG 
TCTTTCCACA AGGTGCTCAA GGGTCTTTAT GAGAAGGGCA GAAAGATGGA CTGGAAGGTG 
CCTGAGCCTG AGGGCCAAAC AAGTCCCAAG AATGCAGCTG TCTTCTCCTC AGTGCTGGCG 
CTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001159751.2
CDS	254..3859
Translation	MNFEGLDPGLAEYAPAMHSALDPVLDAHLNPSLLQNVELDPEGVALEALPVQESVHIMEGVYSELHSVVAEVGVPVSVSHFDLHEEMLWVGSHGGHATSFFGPALERYSSFQVNGSDDIRQIQSLENGILFLTKNNLKYMARGGLIIFDYLLDENEDMHSLLLTDSSTLLVGGLQNHIIEIDLNTVQETQKYAVETPGVTIMRQTNRFFFCGHTSGKVSLRDLRTFKVEHEFDAFSGSLSDFDVHGNLLAACGFSSRLTGLACDRFLKVYDLRMMRAITPLQVHVDPAFLRFIPTYTSRLAIISQSGQCQFCEPTGLANPADIFHVNPVGPLLMTFDVSASKQALAFGDSEGCVHLWTDSPEPSFNPYSRETEFALPCLVDSLPPLDWSQDLLPLSLIPVPLTTDTLLSDWPAANSAPAPRRAPPVDAEILRTMKKVGFIGYAPNPRTRLRNQIPYRLKESDSEFDSFSQVTESPVGREEEPHLHMVSKKYRKVTIKYSKLGLEDFDFKHYNKTLFAGLEPHIPNAYCNCMIQVLYFLEPVRCLIQNHLCQKEFCLACELGFLFHMLDLSRGDPCQGNNFLRAFRTIPEASALGLILADSDEASGKGNLARLIQRWNRFILTQLHQDMQELEIPQAYRGAGGSFCSSGDSVIGQLFSCEMENCSLCRCGSETVRASSTLLFTLSYPDGSKSDKTGKNYDFAQVLKRSICLDQNTQAWCDTCEKYQPTIQTRNIRHLPDILVINCEVNSSKEADFWRMQAEVAFKMAVKKHGGEISKNKEFALADWKELGSPEGVLVCPSIEELKNVWLPFSIRMKMTKNKGLDVCNWTDGDEMQWGPARAEEEHGVYVYDLMATVVHILDSRTGGSLVAHIKVGETYHQRKEGVTHQQWYLFNDFLIEPIDKHEAVQFDMNWKVPAILYYVKRNLNSRYNLNIKNPIEASVLLAEASLARKQRKTHTTFIPLMLNEMPQIGDLVGLDAEFVTLNEEEAELRSDGTKSTIKPSQMSVARITCVRGQGPNEGIPFIDDYISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYLKLRFLIDIGVKFVGHGLQKDFRVINLMVPKDQVLDTVYLFHMPRKRMISLRFLAWYFLDLKIQGETHDSIEDARTALQLYRKYLELSKNGTEPESFHKVLKGLYEKGRKMDWKVPEPEGQTSPKNAAVFSSVLAL

Target ORF information:

RefSeq Version	NM_001166279.2
Organism	Homo sapiens(human)
Definition	Homo sapiens poly(A) specific ribonuclease subunit PAN2 (PAN2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001166279.2

ORF Insert Sequence:

ATGAACTTTG AGGGTCTGGA CCCTGGACTG GCAGAATATG CCCCAGCCAT GCATTCTGCC 
CTGGACCCTG TCTTGGATGC CCACCTGAAC CCAAGTCTGC TACAGAATGT GGAGCTGGAC 
CCAGAGGGAG TGGCCTTGGA GGCTCTTCCC GTCCAGGAAT CAGTGCACAT AATGGAAGGT 
GTCTACTCTG AATTGCACAG CGTGGTGGCT GAAGTGGGTG TACCTGTTTC CGTCTCCCAC 
TTTGACTTGC ACGAGGAGAT GCTGTGGGTG GGGAGCCACG GGGGCCATGC CACTTCATTT 
TTTGGCCCAG CCTTGGAGCG CTACTCATCC TTTCAAGTCA ATGGCAGTGA TGATATTCGG 
CAGATCCAGA GCCTGGAGAA TGGTATCCTT TTTCTCACCA AGAACAACCT CAAGTATATG 
GCCCGTGGGG GCCTCATTAT ATTTGATTAC CTGCTGGATG AGAATGAGGA TATGCACAGT 
CTCCTACTGA CTGACAGCAG CACTCTACTC GTTGGTGGGC TGCAGAATCA CATAATAGAG 
ATTGATCTTA ACACTGTCCA GGAGACTCAG AAGTATGCAG TAGAGACGCC TGGAGTCACC 
ATCATGAGAC AGACAAATCG CTTCTTCTTC TGCGGCCACA CGTCTGGCAA GGTTTCCCTG 
AGAGACCTCC GTACTTTTAA GGTGGAACAT GAGTTTGATG CCTTCTCAGG AAGTCTGTCA 
GACTTTGATG TGCATGGCAA CCTGCTAGCT GCCTGTGGCT TCTCCAGCCG CCTCACTGGC 
CTGGCCTGCG ACCGTTTCCT CAAGGTGTAT GATTTGCGCA TGATGCGTGC CATCACACCA 
CTTCAAGTAC ATGTGGATCC TGCCTTCTTG CGCTTCATTC CTACATATAC TTCTCGTCTT 
GCTATCATCT CTCAGTCAGG GCAGTGCCAA TTCTGTGAAC CCACAGGCCT GGCCAACCCA 
GCCGATATCT TTCATGTGAA TCCTGTGGGG CCTCTGCTAA TGACATTTGA TGTGTCAGCC 
AGCAAGCAGG CTCTGGCCTT TGGGGATTCT GAGGGCTGTG TGCACCTCTG GACTGATTCC 
CCGGAGCCTT CCTTCAACCC CTACTCCCGT GAGACTGAGT TTGCTTTGCC GTGTCTCGTG 
GACTCACTGC CTCCTCTGGA CTGGAGCCAG GACCTGCTGC CTCTTTCCCT CATCCCTGTC 
CCACTCACCA CTGACACACT TCTCTCTGAT TGGCCTGCTG CCAACTCTGC TCCAGCTCCC 
AGGCGAGCAC CACCCGTGGA TGCAGAGATT CTGCGCACCA TGAAGAAGGT GGGCTTCATT 
GGCTATGCGC CCAATCCCCG CACCAGGCTG CGCAATCAGA TACCCTACAG ACTCAAGGAG 
TCAGACAGTG AATTTGACAG CTTCAGCCAG GTCACTGAGT CACCAGTAGG ACGAGAAGAG 
GAACCACATC TCCACATGGT TTCTAAGAAA TACCGCAAGG TGACCATCAA ATATTCCAAG 
CTAGGGCTGG AGGACTTTGA CTTCAAACAC TACAATAAGA CCTTGTTTGC TGGATTAGAG 
CCCCACATTC CCAACGCCTA CTGTAACTGC ATGATCCAGG TGCTCTATTT CCTGGAGCCT 
GTACGCTGTC TAATTCAAAA CCACCTTTGC CAGAAGGAGT TCTGTCTGGC ATGTGAGCTG 
GGCTTCCTGT TTCACATGTT GGACCTCTCT CGTGGTGACC CTTGCCAGGG CAATAATTTT 
CTTCGGGCAT TCCGTACTAT TCCTGAGGCC TCAGCCCTCG GTCTAATCCT GGCTGACTCA 
GATGAGGCCT CAGGCAAGGG CAATCTGGCC AGGCTCATTC AGAGGTGGAA TCGCTTCATT 
CTCACTCAAC TGCATCAAGA TATGCAGGAG CTGGAAATAC CACAGGCTTA TCGAGGTGCT 
GGAGGCAGCT TTTGCTCATC GGGGGACTCT GTTATTGGGC AGCTCTTCAG CTGTGAGATG 
GAGAACTGCA GCCTCTGCCG CTGTGGCAGT GAGACCGTGC GAGCCTCATC CACTCTGCTT 
TTCACACTCT CCTACCCTGA TGGTAGCAAA AGTGATAAAA CTGGGAAGAA CTATGACTTT 
GCTCAGGTGC TGAAGCGAAG CATCTGCCTG GACCAGAATA CACAGGCCTG GTGTGACACC 
TGTGAAAAGT ACCAGCCCAC GATTCAGACC CGCAACATCC GCCATCTGCC AGATATTCTT 
GTCATCAATT GTGAGGTGAA CAGCTCAAAA GAGGCTGATT TCTGGAGAAT GCAGGCTGAG 
GTTGCCTTCA AGATGGCAGT AAAGAAACAC GGTGGGGAAA TCTCCAAGAA CAAGGAATTT 
GCTTTGGCTG ATTGGAAGGA ACTAGGGAGT CCAGAGGGTG TGCTGGTGTG TCCCTCCATT 
GAGGAGTTGA AGAACGTCTG GCTTCCTTTC TCCATTCGCA TGAAGATGAC CAAAAACAAA 
GGGCTGGATG TTTGCAATTG GACTGATGGG GATGAGATGC AGTGGGGCCC AGCCAGGGCA 
GAGGAGGAGC ATGGTGTCTA TGTGTATGAC CTGATGGCTA CTGTGGTACA CATCCTGGAC 
TCACGCACAG GGGGCAGCCT GGTGGCTCAC ATCAAAGTTG GAGAGACCTA CCACCAGCGC 
AAGGAGGGCG TTACTCACCA GCAGTGGTAT CTGTTCAATG ACTTTCTTAT TGAACCTATT 
GATAAGCATG AAGCTGTGCA GTTTGACATG AATTGGAAAG TACCTGCAAT CCTTTATTAT 
GTCAAACGGA ATCTCAATTC CAGATACAAC CTGAACATCA AGAACCCTAT TGAGGCAAGT 
GTCTTGCTGG CTGAAGCCTC GCTGGCACGG AAGCAGCGGA AAACACATAC TACCTTTATT 
CCACTGATGC TGAATGAGAT GCCACAGATT GGGGACCTGG TGGGTCTGGA TGCTGAGTTT 
GTCACCCTTA ATGAGGAGGA AGCAGAGTTA CGCAGTGATG GTACCAAGTC TACCATTAAA 
CCAAGCCAGA TGTCAGTAGC CAGGATTACC TGTGTTCGGG GCCAGGGACC CAATGAGGGT 
ATCCCCTTCA TTGATGACTA CATCTCTACC CAGGAGCAGG TGGTGGATTA CTTGACTCAA 
TACTCGGGTA TAAAGCCTGG TGACCTCGAT GCCAAAATTT CCTCCAAGCA CCTAACAACT 
CTCAAGTCTA CCTACTTAAA GCTTCGTTTT CTCATTGACA TTGGAGTCAA GTTTGTGGGT 
CATGGCCTGC AGAAGGACTT CCGGGTCATC AACCTGATGG TGCCCAAGGA CCAAGTCCTT 
GACACTGTCT ACCTGTTCCA TATGCCCCGA AAACGAATGA TTTCCCTGCG ATTCCTTGCT 
TGGTACTTTC TGGACCTGAA GATTCAAGGG GAAACCCATG ACAGTATTGA GGATGCCCGC 
ACAGCCCTTC AGCTGTACCG AAAGTATCTG GAGCTAAGCA AAAATGGCAC TGAGCCTGAG 
TCTTTCCACA AGGTGCTCAA GGGTCTTTAT GAGAAGGGCA GAAAGATGGA CTGGAAGGTG 
CCTGAGCCTG AGGGCCAAAC AAGTCCCAAG AATGCAGCTG TCTTCTCCTC AGTGCTGGCG 
CTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PAN2 ( NM_001127460.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001120932.1 Homo sapiens poly(A) specific ribonuclease subunit PAN2 (PAN2), transcript variant 1, mRNA.

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CloneID	OHu16340
Clone ID Related Accession (Same CDS sequence)	NM_001127460.2
Accession Version	NM_001127460.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3609bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB458902.1, BC094885.1 and AC073896.41. On Oct 23, 2009 this sequence version replaced NM_001127460.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC094885.1, SRR1803615.14694.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACTTTG AGGGTCTGGA CCCTGGACTG GCAGAATATG CCCCAGCCAT GCATTCTGCC 
CTGGACCCTG TCTTGGATGC CCACCTGAAC CCAAGTCTGC TACAGAATGT GGAGCTGGAC 
CCAGAGGGAG TGGCCTTGGA GGCTCTTCCC GTCCAGGAAT CAGTGCACAT AATGGAAGGT 
GTCTACTCTG AATTGCACAG CGTGGTGGCT GAAGTGGGTG TACCTGTTTC CGTCTCCCAC 
TTTGACTTGC ACGAGGAGAT GCTGTGGGTG GGGAGCCACG GGGGCCATGC CACTTCATTT 
TTTGGCCCAG CCTTGGAGCG CTACTCATCC TTTCAAGTCA ATGGCAGTGA TGATATTCGG 
CAGATCCAGA GCCTGGAGAA TGGTATCCTT TTTCTCACCA AGAACAACCT CAAGTATATG 
GCCCGTGGGG GCCTCATTAT ATTTGATTAC CTGCTGGATG AGAATGAGGA TATGCACAGT 
CTCCTACTGA CTGACAGCAG CACTCTACTC GTTGGTGGGC TGCAGAATCA CATACTAGAG 
ATTGATCTTA ACACTGTCCA GGAGACTCAG AAGTATGCAG TAGAGACGCC TGGAGTCACC 
ATCATGAGAC AGACAAATCG CTTCTTCTTC TGCGGCCACA CGTCTGGCAA GGTTTCCCTG 
AGAGACCTCC GTACTTTTAA GGTGGAACAT GAGTTTGATG CCTTCTCAGG AAGTCTGTCA 
GACTTTGATG TGCATGGCAA CCTGCTAGCT GCCTGTGGCT TCTCCAGCCG CCTCACTGGC 
CTGGCCTGCG ACCGTTTCCT CAAGGTGTAT GATTTGCGCA TGATGCGTGC CATCACACCA 
CTTCAAGTAC ATGTGGATCC TGCCTTCTTG CGCTTCATTC CTACATATAC TTCTCGTCTT 
GCTATCATCT CTCAGTCAGG GCAGTGCCAA TTCTGTGAAC CCACAGGCCT GGCCAACCCA 
GCCGATATCT TTCATGTGAA TCCTGTGGGG CCTCTGCTAA TGACATTTGA TGTGTCAGCC 
AGCAAGCAGG CTCTGGCCTT TGGGGATTCT GAGGGCTGTG TGCACCTCTG GACTGATTCC 
CCGGAGCCTT CCTTCAACCC CTACTCCCGT GAGACTGAGT TTGCTTTGCC GTGTCTCGTG 
GACTCACTGC CTCCTCTGGA CTGGAGCCAG GACCTGCTGC CTCTTTCCCT CATCCCTGTC 
CCACTCACCA CTGACACACT TCTCTCTGAT TGGCCTGCTG CCAACTCTGC TCCAGCTCCC 
AGGCGAGCAC CACCCGTGGA TGCAGAGATT CTGCGCACCA TGAAGAAGGT GGGCTTCATT 
GGCTATGCGC CCAATCCCCG CACCAGGCTG CGCAATCAGA TACCCTACAG ACTCAAGGAG 
TCAGACAGTG AATTTGACAG CTTCAGCCAG GTCACTGAGT CACCAGTAGG ACGAGAAGAG 
GAACCACATC TCCACATGGT TTCTAAGAAA TACCGCAAGG TGACCATCAA ATATTCCAAG 
CTAGGGCTGG AGGACTTTGA CTTCAAACAC TACAATAAGA CCTTGTTTGC TGGATTAGAG 
CCCCACATTC CCAACGCCTA CTGTAACTGC ATGATCCAGG TGCTCTATTT CCTGGAGCCT 
GTACGCTGTC TAATTCAAAA CCACCTTTGC CAGAAGGAGT TCTGTCTGGC ATGTGAGCTG 
GGCTTCCTGT TTCACATGTT GGACCTCTCT CGTGGTGACC CTTGCCAGGG CAATAATTTT 
CTTCGGGCAT TCCGTACTAT TCCTGAGGCC TCAGCCCTCG GTCTAATCCT GGCTGACTCA 
GATGAGGCCT CAGGCAAGGG CAATCTGGCC AGGCTCATTC AGAGGTGGAA TCGCTTCATT 
CTCACTCAAC TGCATCAAGA TATGCAGGAG CTGGAAATAC CACAGGCTTA TCGAGGTGCT 
GGAGGCAGCA GCTTTTGCTC ATCGGGGGAC TCTGTTATTG GGCAGCTCTT CAGCTGTGAG 
ATGGAGAACT GCAGCCTCTG CCGCTGTGGC AGTGAGACCG TGCGAGCCTC ATCCACTCTG 
CTTTTCACAC TCTCCTACCC TGATGGTAGC AAAAGTGATA AAACTGGGAA GAACTATGAC 
TTTGCTCAGG TGCTGAAGCG AAGCATCTGC CTGGACCAGA ATACACAGGC CTGGTGTGAC 
ACCTGTGAAA AGTACCAGCC CACGATTCAG ACCCGCAACA TCCGCCATCT GCCAGATATT 
CTTGTCATCA ATTGTGAGGT GAACAGCTCA AAAGAGGCTG ATTTCTGGAG AATGCAGGCT 
GAGGTTGCCT TCAAGATGGC AGTAAAGAAA CACGGTGGGG AAATCTCCAA GAACAAGGAA 
TTTGCTTTGG CTGATTGGAA GGAACTAGGG AGTCCAGAGG GTGTGCTGGT GTGTCCCTCC 
ATTGAGGAGT TGAAGAACGT CTGGCTTCCT TTCTCCATTC GCATGAAGAT GACCAAAAAC 
AAAGGGCTGG ATGTTTGCAA TTGGACTGAT GGGGATGAGA TGCAGTGGGG CCCAGCCAGG 
GCAGAGGAGG AGCATGGTGT CTATGTGTAT GACCTGATGG CTACTGTGGT ACACATCCTG 
GACTCACGCA CAGGGGGCAG CCTGGTGGCT CACATCAAAG TTGGAGAGAC CTACCACCAG 
CGCAAGGAGG GCGTTACTCA CCAGCAGTGG TATCTGTTCA ATGACTTTCT TATTGAACCT 
ATTGATAAGC ATGAAGCTGT GCAGTTTGAC ATGAATTGGA AAGTACCTGC AATCCTTTAT 
TATGTCAAAC GGAATCTCAA TTCCAGATAC AACCTGAACA TCAAGAACCC TATTGAGGCA 
AGTGTCTTGC TGGCTGAAGC CTCGCTGGCA CGGAAGCAGC GGAAAACACA TACTACCTTT 
ATTCCACTGA TGCTGAATGA GATGCCACAG ATTGGGGACC TGGTGGGTCT GGATGCTGAG 
TTTGTCACCC TTAATGAGGA GGAAGCAGAG TTACGCAGTG ATGGTACCAA GTCTACCATT 
AAACCAAGCC AGATGTCAGT AGCCAGGATT ACCTGTGTTC GGGGCCAGGG ACCCAATGAG 
GGTATCCCCT TCATTGATGA CTACATCTCT ACCCAGGAGC AGGTGGTGGA TTACTTGACT 
CAATACTCGG GTATAAAGCC TGGTGACCTC GATGCCAAAA TTTCCTCCAA GCACCTAACA 
ACTCTCAAGT CTACCTACTT AAAGCTTCGT TTTCTCATTG ACATTGGAGT CAAGTTTGTG 
GGTCATGGCC TGCAGAAGGA CTTCCGGGTC ATCAACCTGA TGGTGCCCAA GGACCAAGTC 
CTTGACACTG TCTACCTGTT CCATATGCCC CGAAAACGAA TGATTTCCCT GCGATTCCTT 
GCTTGGTACT TTCTGGACCT GAAGATTCAA GGGGAAACCC ATGACAGTAT TGAGGATGCC 
CGCACAGCCC TTCAGCTGTA CCGAAAGTAT CTGGAGCTAA GCAAAAATGG CACTGAGCCT 
GAGTCTTTCC ACAAGGTGCT CAAGGGTCTT TATGAGAAGG GCAGAAAGAT GGACTGGAAG 
GTGCCTGAGC CTGAGGGCCA AACAAGTCCC AAGAATGCAG CTGTCTTCTC CTCAGTGCTG 
GCGCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001120932.1
CDS	378..3986
Translation	MNFEGLDPGLAEYAPAMHSALDPVLDAHLNPSLLQNVELDPEGVALEALPVQESVHIMEGVYSELHSVVAEVGVPVSVSHFDLHEEMLWVGSHGGHATSFFGPALERYSSFQVNGSDDIRQIQSLENGILFLTKNNLKYMARGGLIIFDYLLDENEDMHSLLLTDSSTLLVGGLQNHILEIDLNTVQETQKYAVETPGVTIMRQTNRFFFCGHTSGKVSLRDLRTFKVEHEFDAFSGSLSDFDVHGNLLAACGFSSRLTGLACDRFLKVYDLRMMRAITPLQVHVDPAFLRFIPTYTSRLAIISQSGQCQFCEPTGLANPADIFHVNPVGPLLMTFDVSASKQALAFGDSEGCVHLWTDSPEPSFNPYSRETEFALPCLVDSLPPLDWSQDLLPLSLIPVPLTTDTLLSDWPAANSAPAPRRAPPVDAEILRTMKKVGFIGYAPNPRTRLRNQIPYRLKESDSEFDSFSQVTESPVGREEEPHLHMVSKKYRKVTIKYSKLGLEDFDFKHYNKTLFAGLEPHIPNAYCNCMIQVLYFLEPVRCLIQNHLCQKEFCLACELGFLFHMLDLSRGDPCQGNNFLRAFRTIPEASALGLILADSDEASGKGNLARLIQRWNRFILTQLHQDMQELEIPQAYRGAGGSSFCSSGDSVIGQLFSCEMENCSLCRCGSETVRASSTLLFTLSYPDGSKSDKTGKNYDFAQVLKRSICLDQNTQAWCDTCEKYQPTIQTRNIRHLPDILVINCEVNSSKEADFWRMQAEVAFKMAVKKHGGEISKNKEFALADWKELGSPEGVLVCPSIEELKNVWLPFSIRMKMTKNKGLDVCNWTDGDEMQWGPARAEEEHGVYVYDLMATVVHILDSRTGGSLVAHIKVGETYHQRKEGVTHQQWYLFNDFLIEPIDKHEAVQFDMNWKVPAILYYVKRNLNSRYNLNIKNPIEASVLLAEASLARKQRKTHTTFIPLMLNEMPQIGDLVGLDAEFVTLNEEEAELRSDGTKSTIKPSQMSVARITCVRGQGPNEGIPFIDDYISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYLKLRFLIDIGVKFVGHGLQKDFRVINLMVPKDQVLDTVYLFHMPRKRMISLRFLAWYFLDLKIQGETHDSIEDARTALQLYRKYLELSKNGTEPESFHKVLKGLYEKGRKMDWKVPEPEGQTSPKNAAVFSSVLAL

Target ORF information:

RefSeq Version	NM_001127460.2
Organism	Homo sapiens(human)
Definition	Homo sapiens poly(A) specific ribonuclease subunit PAN2 (PAN2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001127460.2

ORF Insert Sequence:

ATGAACTTTG AGGGTCTGGA CCCTGGACTG GCAGAATATG CCCCAGCCAT GCATTCTGCC 
CTGGACCCTG TCTTGGATGC CCACCTGAAC CCAAGTCTGC TACAGAATGT GGAGCTGGAC 
CCAGAGGGAG TGGCCTTGGA GGCTCTTCCC GTCCAGGAAT CAGTGCACAT AATGGAAGGT 
GTCTACTCTG AATTGCACAG CGTGGTGGCT GAAGTGGGTG TACCTGTTTC CGTCTCCCAC 
TTTGACTTGC ACGAGGAGAT GCTGTGGGTG GGGAGCCACG GGGGCCATGC CACTTCATTT 
TTTGGCCCAG CCTTGGAGCG CTACTCATCC TTTCAAGTCA ATGGCAGTGA TGATATTCGG 
CAGATCCAGA GCCTGGAGAA TGGTATCCTT TTTCTCACCA AGAACAACCT CAAGTATATG 
GCCCGTGGGG GCCTCATTAT ATTTGATTAC CTGCTGGATG AGAATGAGGA TATGCACAGT 
CTCCTACTGA CTGACAGCAG CACTCTACTC GTTGGTGGGC TGCAGAATCA CATACTAGAG 
ATTGATCTTA ACACTGTCCA GGAGACTCAG AAGTATGCAG TAGAGACGCC TGGAGTCACC 
ATCATGAGAC AGACAAATCG CTTCTTCTTC TGCGGCCACA CGTCTGGCAA GGTTTCCCTG 
AGAGACCTCC GTACTTTTAA GGTGGAACAT GAGTTTGATG CCTTCTCAGG AAGTCTGTCA 
GACTTTGATG TGCATGGCAA CCTGCTAGCT GCCTGTGGCT TCTCCAGCCG CCTCACTGGC 
CTGGCCTGCG ACCGTTTCCT CAAGGTGTAT GATTTGCGCA TGATGCGTGC CATCACACCA 
CTTCAAGTAC ATGTGGATCC TGCCTTCTTG CGCTTCATTC CTACATATAC TTCTCGTCTT 
GCTATCATCT CTCAGTCAGG GCAGTGCCAA TTCTGTGAAC CCACAGGCCT GGCCAACCCA 
GCCGATATCT TTCATGTGAA TCCTGTGGGG CCTCTGCTAA TGACATTTGA TGTGTCAGCC 
AGCAAGCAGG CTCTGGCCTT TGGGGATTCT GAGGGCTGTG TGCACCTCTG GACTGATTCC 
CCGGAGCCTT CCTTCAACCC CTACTCCCGT GAGACTGAGT TTGCTTTGCC GTGTCTCGTG 
GACTCACTGC CTCCTCTGGA CTGGAGCCAG GACCTGCTGC CTCTTTCCCT CATCCCTGTC 
CCACTCACCA CTGACACACT TCTCTCTGAT TGGCCTGCTG CCAACTCTGC TCCAGCTCCC 
AGGCGAGCAC CACCCGTGGA TGCAGAGATT CTGCGCACCA TGAAGAAGGT GGGCTTCATT 
GGCTATGCGC CCAATCCCCG CACCAGGCTG CGCAATCAGA TACCCTACAG ACTCAAGGAG 
TCAGACAGTG AATTTGACAG CTTCAGCCAG GTCACTGAGT CACCAGTAGG ACGAGAAGAG 
GAACCACATC TCCACATGGT TTCTAAGAAA TACCGCAAGG TGACCATCAA ATATTCCAAG 
CTAGGGCTGG AGGACTTTGA CTTCAAACAC TACAATAAGA CCTTGTTTGC TGGATTAGAG 
CCCCACATTC CCAACGCCTA CTGTAACTGC ATGATCCAGG TGCTCTATTT CCTGGAGCCT 
GTACGCTGTC TAATTCAAAA CCACCTTTGC CAGAAGGAGT TCTGTCTGGC ATGTGAGCTG 
GGCTTCCTGT TTCACATGTT GGACCTCTCT CGTGGTGACC CTTGCCAGGG CAATAATTTT 
CTTCGGGCAT TCCGTACTAT TCCTGAGGCC TCAGCCCTCG GTCTAATCCT GGCTGACTCA 
GATGAGGCCT CAGGCAAGGG CAATCTGGCC AGGCTCATTC AGAGGTGGAA TCGCTTCATT 
CTCACTCAAC TGCATCAAGA TATGCAGGAG CTGGAAATAC CACAGGCTTA TCGAGGTGCT 
GGAGGCAGCA GCTTTTGCTC ATCGGGGGAC TCTGTTATTG GGCAGCTCTT CAGCTGTGAG 
ATGGAGAACT GCAGCCTCTG CCGCTGTGGC AGTGAGACCG TGCGAGCCTC ATCCACTCTG 
CTTTTCACAC TCTCCTACCC TGATGGTAGC AAAAGTGATA AAACTGGGAA GAACTATGAC 
TTTGCTCAGG TGCTGAAGCG AAGCATCTGC CTGGACCAGA ATACACAGGC CTGGTGTGAC 
ACCTGTGAAA AGTACCAGCC CACGATTCAG ACCCGCAACA TCCGCCATCT GCCAGATATT 
CTTGTCATCA ATTGTGAGGT GAACAGCTCA AAAGAGGCTG ATTTCTGGAG AATGCAGGCT 
GAGGTTGCCT TCAAGATGGC AGTAAAGAAA CACGGTGGGG AAATCTCCAA GAACAAGGAA 
TTTGCTTTGG CTGATTGGAA GGAACTAGGG AGTCCAGAGG GTGTGCTGGT GTGTCCCTCC 
ATTGAGGAGT TGAAGAACGT CTGGCTTCCT TTCTCCATTC GCATGAAGAT GACCAAAAAC 
AAAGGGCTGG ATGTTTGCAA TTGGACTGAT GGGGATGAGA TGCAGTGGGG CCCAGCCAGG 
GCAGAGGAGG AGCATGGTGT CTATGTGTAT GACCTGATGG CTACTGTGGT ACACATCCTG 
GACTCACGCA CAGGGGGCAG CCTGGTGGCT CACATCAAAG TTGGAGAGAC CTACCACCAG 
CGCAAGGAGG GCGTTACTCA CCAGCAGTGG TATCTGTTCA ATGACTTTCT TATTGAACCT 
ATTGATAAGC ATGAAGCTGT GCAGTTTGAC ATGAATTGGA AAGTACCTGC AATCCTTTAT 
TATGTCAAAC GGAATCTCAA TTCCAGATAC AACCTGAACA TCAAGAACCC TATTGAGGCA 
AGTGTCTTGC TGGCTGAAGC CTCGCTGGCA CGGAAGCAGC GGAAAACACA TACTACCTTT 
ATTCCACTGA TGCTGAATGA GATGCCACAG ATTGGGGACC TGGTGGGTCT GGATGCTGAG 
TTTGTCACCC TTAATGAGGA GGAAGCAGAG TTACGCAGTG ATGGTACCAA GTCTACCATT 
AAACCAAGCC AGATGTCAGT AGCCAGGATT ACCTGTGTTC GGGGCCAGGG ACCCAATGAG 
GGTATCCCCT TCATTGATGA CTACATCTCT ACCCAGGAGC AGGTGGTGGA TTACTTGACT 
CAATACTCGG GTATAAAGCC TGGTGACCTC GATGCCAAAA TTTCCTCCAA GCACCTAACA 
ACTCTCAAGT CTACCTACTT AAAGCTTCGT TTTCTCATTG ACATTGGAGT CAAGTTTGTG 
GGTCATGGCC TGCAGAAGGA CTTCCGGGTC ATCAACCTGA TGGTGCCCAA GGACCAAGTC 
CTTGACACTG TCTACCTGTT CCATATGCCC CGAAAACGAA TGATTTCCCT GCGATTCCTT 
GCTTGGTACT TTCTGGACCT GAAGATTCAA GGGGAAACCC ATGACAGTAT TGAGGATGCC 
CGCACAGCCC TTCAGCTGTA CCGAAAGTAT CTGGAGCTAA GCAAAAATGG CACTGAGCCT 
GAGTCTTTCC ACAAGGTGCT CAAGGGTCTT TATGAGAAGG GCAGAAAGAT GGACTGGAAG 
GTGCCTGAGC CTGAGGGCCA AACAAGTCCC AAGAATGCAG CTGTCTTCTC CTCAGTGCTG 
GCGCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PAN2 ( NM_014871.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_055686.3 Homo sapiens poly(A) specific ribonuclease subunit PAN2 (PAN2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu16345
Clone ID Related Accession (Same CDS sequence)	NM_014871.4
Accession Version	NM_014871.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3597bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC025574.19, BC024043.1 and AC073896.41. On Oct 23, 2009 this sequence version replaced NM_014871.3. Transcript Variant: This variant (3) uses an alternate in-frame splice site in the coding region, compared to variant 1. The encoded isoform (3) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.53282.1, SRR1803616.180738.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACTTTG AGGGTCTGGA CCCTGGACTG GCAGAATATG CCCCAGCCAT GCATTCTGCC 
CTGGACCCTG TCTTGGATGC CCACCTGAAC CCAAGTCTGC TACAGAATGT GGAGCTGGAC 
CCAGAGGGAG TGGCCTTGGA GGCTCTTCCC GTCCAGGAAT CAGTGCACAT AATGGAAGGT 
GTCTACTCTG AATTGCACAG CGTGGTGGCT GAAGTGGGTG TACCTGTTTC CGTCTCCCAC 
TTTGACTTGC ACGAGGAGAT GCTGTGGGTG GGGAGCCACG GGGGCCATGC CACTTCATTT 
TTTGGCCCAG CCTTGGAGCG CTACTCATCC TTTCAAGTCA ATGGCAGTGA TGATATTCGG 
CAGATCCAGA GCCTGGAGAA TGGTATCCTT TTTCTCACCA AGAACAACCT CAAGTATATG 
GCCCGTGGGG GCCTCATTAT ATTTGATTAC CTGCTGGATG AGAATGAGGA TATGCACAGT 
CTCCTACTGA CTGACAGCAG CACTCTACTC GTTGGTGGGC TGCAGAATCA CATACTAGAG 
ATTGATCTTA ACACTGTCCA GGAGACTCAG AAGTATGCAG TAGAGACGCC TGGAGTCACC 
ATCATGAGAC AGACAAATCG CTTCTTCTTC TGCGGCCACA CGTCTGGCAA GGTTTCCCTG 
AGAGACCTCC GTACTTTTAA GGTGGAACAT GAGTTTGATG CCTTCTCAGG AAGTCTGTCA 
GACTTTGATG TGCATGGCAA CCTGCTAGCT GCCTGTGGCT TCTCCAGCCG CCTCACTGGC 
CTGGCCTGCG ACCGTTTCCT CAAGGTGTAT GATTTGCGCA TGATGCGTGC CATCACACCA 
CTTCAAGTAC ATGTGGATCC TGCCTTCTTG CGCTTCATTC CTACATATAC TTCTCGTCTT 
GCTATCATCT CTCAGTCAGG GCAGTGCCAA TTCTGTGAAC CCACAGGCCT GGCCAACCCA 
GCCGATATCT TTCATGTGAA TCCTGTGGGG CCTCTGCTAA TGACATTTGA TGTGTCAGCC 
AGCAAGCAGG CTCTGGCCTT TGGGGATTCT GAGGGCTGTG TGCACCTCTG GACTGATTCC 
CCGGAGCCTT CCTTCAACCC CTACTCCCGT GAGACTGAGT TTGCTTTGCC GTGTCTCGTG 
GACTCACTGC CTCCTCTGGA CTGGAGCCAG GACCTGCTGC CTCTTTCCCT CATCCCTGTC 
CCACTCACCA CTGACACACT TCTCTCTGAT TGGCCTGCTG CCAACTCTGC TCCAGCTCCC 
AGGCGAGCAC CACCCGTGGA TGCAGAGATT CTGCGCACCA TGAAGAAGGT GGGCTTCATT 
GGCTATGCGC CCAATCCCCG CACCAGGCTG CGCAATCAGA TACCCTACAG ACTCAAGGAG 
TCAGACAGTG AATTTGACAG CTTCAGCCAG GTCACTGAGT CACCAGTAGG ACGAGAAGAG 
GAACCACATC TCCACATGGT TTCTAAGAAA TACCGCAAGG TGACCATCAA ATATTCCAAG 
CTAGGGCTGG AGGACTTTGA CTTCAAACAC TACAATAAGA CCTTGTTTGC TGGATTAGAG 
CCCCACATTC CCAACGCCTA CTGTAACTGC ATGATCCAGG TGCTCTATTT CCTGGAGCCT 
GTACGCTGTC TAATTCAAAA CCACCTTTGC CAGAAGGAGT TCTGTCTGGC ATGTGAGCTG 
GGCTTCCTGT TTCACATGTT GGACCTCTCT CGTGGTGACC CTTGCCAGGG CAATAATTTT 
CTTCGGGCAT TCCGTACTAT TCCTGAGGCC TCAGCCCTCG GTCTAATCCT GGCTGACTCA 
GATGAGGCCT CAGGCAAGGG CAATCTGGCC AGGCTCATTC AGAGGTGGAA TCGCTTCATT 
CTCACTCAAC TGCATCAAGA TATGCAGGAG CTGGAAATAC CACAGGCTTA TCGAGGTGCT 
GGAGGCAGCA GCTTTTGCTC ATCGGGGGAC TCTGTTATTG GGCAGCTCTT CAGCTGTGAG 
ATGGAGAACT GCAGCCTCTG CCGCTGTGGC AGTGAGACCG TGCGAGCCTC ATCCACTCTG 
CTTTTCACAC TCTCCTACCC TGATGATAAA ACTGGGAAGA ACTATGACTT TGCTCAGGTG 
CTGAAGCGAA GCATCTGCCT GGACCAGAAT ACACAGGCCT GGTGTGACAC CTGTGAAAAG 
TACCAGCCCA CGATTCAGAC CCGCAACATC CGCCATCTGC CAGATATTCT TGTCATCAAT 
TGTGAGGTGA ACAGCTCAAA AGAGGCTGAT TTCTGGAGAA TGCAGGCTGA GGTTGCCTTC 
AAGATGGCAG TAAAGAAACA CGGTGGGGAA ATCTCCAAGA ACAAGGAATT TGCTTTGGCT 
GATTGGAAGG AACTAGGGAG TCCAGAGGGT GTGCTGGTGT GTCCCTCCAT TGAGGAGTTG 
AAGAACGTCT GGCTTCCTTT CTCCATTCGC ATGAAGATGA CCAAAAACAA AGGGCTGGAT 
GTTTGCAATT GGACTGATGG GGATGAGATG CAGTGGGGCC CAGCCAGGGC AGAGGAGGAG 
CATGGTGTCT ATGTGTATGA CCTGATGGCT ACTGTGGTAC ACATCCTGGA CTCACGCACA 
GGGGGCAGCC TGGTGGCTCA CATCAAAGTT GGAGAGACCT ACCACCAGCG CAAGGAGGGC 
GTTACTCACC AGCAGTGGTA TCTGTTCAAT GACTTTCTTA TTGAACCTAT TGATAAGCAT 
GAAGCTGTGC AGTTTGACAT GAATTGGAAA GTACCTGCAA TCCTTTATTA TGTCAAACGG 
AATCTCAATT CCAGATACAA CCTGAACATC AAGAACCCTA TTGAGGCAAG TGTCTTGCTG 
GCTGAAGCCT CGCTGGCACG GAAGCAGCGG AAAACACATA CTACCTTTAT TCCACTGATG 
CTGAATGAGA TGCCACAGAT TGGGGACCTG GTGGGTCTGG ATGCTGAGTT TGTCACCCTT 
AATGAGGAGG AAGCAGAGTT ACGCAGTGAT GGTACCAAGT CTACCATTAA ACCAAGCCAG 
ATGTCAGTAG CCAGGATTAC CTGTGTTCGG GGCCAGGGAC CCAATGAGGG TATCCCCTTC 
ATTGATGACT ACATCTCTAC CCAGGAGCAG GTGGTGGATT ACTTGACTCA ATACTCGGGT 
ATAAAGCCTG GTGACCTCGA TGCCAAAATT TCCTCCAAGC ACCTAACAAC TCTCAAGTCT 
ACCTACTTAA AGCTTCGTTT TCTCATTGAC ATTGGAGTCA AGTTTGTGGG TCATGGCCTG 
CAGAAGGACT TCCGGGTCAT CAACCTGATG GTGCCCAAGG ACCAAGTCCT TGACACTGTC 
TACCTGTTCC ATATGCCCCG AAAACGAATG ATTTCCCTGC GATTCCTTGC TTGGTACTTT 
CTGGACCTGA AGATTCAAGG GGAAACCCAT GACAGTATTG AGGATGCCCG CACAGCCCTT 
CAGCTGTACC GAAAGTATCT GGAGCTAAGC AAAAATGGCA CTGAGCCTGA GTCTTTCCAC 
AAGGTGCTCA AGGGTCTTTA TGAGAAGGGC AGAAAGATGG ACTGGAAGGT GCCTGAGCCT 
GAGGGCCAAA CAAGTCCCAA GAATGCAGCT GTCTTCTCCT CAGTGCTGGC GCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055686.3
CDS	307..3903
Translation	MNFEGLDPGLAEYAPAMHSALDPVLDAHLNPSLLQNVELDPEGVALEALPVQESVHIMEGVYSELHSVVAEVGVPVSVSHFDLHEEMLWVGSHGGHATSFFGPALERYSSFQVNGSDDIRQIQSLENGILFLTKNNLKYMARGGLIIFDYLLDENEDMHSLLLTDSSTLLVGGLQNHILEIDLNTVQETQKYAVETPGVTIMRQTNRFFFCGHTSGKVSLRDLRTFKVEHEFDAFSGSLSDFDVHGNLLAACGFSSRLTGLACDRFLKVYDLRMMRAITPLQVHVDPAFLRFIPTYTSRLAIISQSGQCQFCEPTGLANPADIFHVNPVGPLLMTFDVSASKQALAFGDSEGCVHLWTDSPEPSFNPYSRETEFALPCLVDSLPPLDWSQDLLPLSLIPVPLTTDTLLSDWPAANSAPAPRRAPPVDAEILRTMKKVGFIGYAPNPRTRLRNQIPYRLKESDSEFDSFSQVTESPVGREEEPHLHMVSKKYRKVTIKYSKLGLEDFDFKHYNKTLFAGLEPHIPNAYCNCMIQVLYFLEPVRCLIQNHLCQKEFCLACELGFLFHMLDLSRGDPCQGNNFLRAFRTIPEASALGLILADSDEASGKGNLARLIQRWNRFILTQLHQDMQELEIPQAYRGAGGSSFCSSGDSVIGQLFSCEMENCSLCRCGSETVRASSTLLFTLSYPDDKTGKNYDFAQVLKRSICLDQNTQAWCDTCEKYQPTIQTRNIRHLPDILVINCEVNSSKEADFWRMQAEVAFKMAVKKHGGEISKNKEFALADWKELGSPEGVLVCPSIEELKNVWLPFSIRMKMTKNKGLDVCNWTDGDEMQWGPARAEEEHGVYVYDLMATVVHILDSRTGGSLVAHIKVGETYHQRKEGVTHQQWYLFNDFLIEPIDKHEAVQFDMNWKVPAILYYVKRNLNSRYNLNIKNPIEASVLLAEASLARKQRKTHTTFIPLMLNEMPQIGDLVGLDAEFVTLNEEEAELRSDGTKSTIKPSQMSVARITCVRGQGPNEGIPFIDDYISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYLKLRFLIDIGVKFVGHGLQKDFRVINLMVPKDQVLDTVYLFHMPRKRMISLRFLAWYFLDLKIQGETHDSIEDARTALQLYRKYLELSKNGTEPESFHKVLKGLYEKGRKMDWKVPEPEGQTSPKNAAVFSSVLAL

Target ORF information:

RefSeq Version	NM_014871.4
Organism	Homo sapiens(human)
Definition	Homo sapiens poly(A) specific ribonuclease subunit PAN2 (PAN2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014871.4

ORF Insert Sequence:

ATGAACTTTG AGGGTCTGGA CCCTGGACTG GCAGAATATG CCCCAGCCAT GCATTCTGCC 
CTGGACCCTG TCTTGGATGC CCACCTGAAC CCAAGTCTGC TACAGAATGT GGAGCTGGAC 
CCAGAGGGAG TGGCCTTGGA GGCTCTTCCC GTCCAGGAAT CAGTGCACAT AATGGAAGGT 
GTCTACTCTG AATTGCACAG CGTGGTGGCT GAAGTGGGTG TACCTGTTTC CGTCTCCCAC 
TTTGACTTGC ACGAGGAGAT GCTGTGGGTG GGGAGCCACG GGGGCCATGC CACTTCATTT 
TTTGGCCCAG CCTTGGAGCG CTACTCATCC TTTCAAGTCA ATGGCAGTGA TGATATTCGG 
CAGATCCAGA GCCTGGAGAA TGGTATCCTT TTTCTCACCA AGAACAACCT CAAGTATATG 
GCCCGTGGGG GCCTCATTAT ATTTGATTAC CTGCTGGATG AGAATGAGGA TATGCACAGT 
CTCCTACTGA CTGACAGCAG CACTCTACTC GTTGGTGGGC TGCAGAATCA CATACTAGAG 
ATTGATCTTA ACACTGTCCA GGAGACTCAG AAGTATGCAG TAGAGACGCC TGGAGTCACC 
ATCATGAGAC AGACAAATCG CTTCTTCTTC TGCGGCCACA CGTCTGGCAA GGTTTCCCTG 
AGAGACCTCC GTACTTTTAA GGTGGAACAT GAGTTTGATG CCTTCTCAGG AAGTCTGTCA 
GACTTTGATG TGCATGGCAA CCTGCTAGCT GCCTGTGGCT TCTCCAGCCG CCTCACTGGC 
CTGGCCTGCG ACCGTTTCCT CAAGGTGTAT GATTTGCGCA TGATGCGTGC CATCACACCA 
CTTCAAGTAC ATGTGGATCC TGCCTTCTTG CGCTTCATTC CTACATATAC TTCTCGTCTT 
GCTATCATCT CTCAGTCAGG GCAGTGCCAA TTCTGTGAAC CCACAGGCCT GGCCAACCCA 
GCCGATATCT TTCATGTGAA TCCTGTGGGG CCTCTGCTAA TGACATTTGA TGTGTCAGCC 
AGCAAGCAGG CTCTGGCCTT TGGGGATTCT GAGGGCTGTG TGCACCTCTG GACTGATTCC 
CCGGAGCCTT CCTTCAACCC CTACTCCCGT GAGACTGAGT TTGCTTTGCC GTGTCTCGTG 
GACTCACTGC CTCCTCTGGA CTGGAGCCAG GACCTGCTGC CTCTTTCCCT CATCCCTGTC 
CCACTCACCA CTGACACACT TCTCTCTGAT TGGCCTGCTG CCAACTCTGC TCCAGCTCCC 
AGGCGAGCAC CACCCGTGGA TGCAGAGATT CTGCGCACCA TGAAGAAGGT GGGCTTCATT 
GGCTATGCGC CCAATCCCCG CACCAGGCTG CGCAATCAGA TACCCTACAG ACTCAAGGAG 
TCAGACAGTG AATTTGACAG CTTCAGCCAG GTCACTGAGT CACCAGTAGG ACGAGAAGAG 
GAACCACATC TCCACATGGT TTCTAAGAAA TACCGCAAGG TGACCATCAA ATATTCCAAG 
CTAGGGCTGG AGGACTTTGA CTTCAAACAC TACAATAAGA CCTTGTTTGC TGGATTAGAG 
CCCCACATTC CCAACGCCTA CTGTAACTGC ATGATCCAGG TGCTCTATTT CCTGGAGCCT 
GTACGCTGTC TAATTCAAAA CCACCTTTGC CAGAAGGAGT TCTGTCTGGC ATGTGAGCTG 
GGCTTCCTGT TTCACATGTT GGACCTCTCT CGTGGTGACC CTTGCCAGGG CAATAATTTT 
CTTCGGGCAT TCCGTACTAT TCCTGAGGCC TCAGCCCTCG GTCTAATCCT GGCTGACTCA 
GATGAGGCCT CAGGCAAGGG CAATCTGGCC AGGCTCATTC AGAGGTGGAA TCGCTTCATT 
CTCACTCAAC TGCATCAAGA TATGCAGGAG CTGGAAATAC CACAGGCTTA TCGAGGTGCT 
GGAGGCAGCA GCTTTTGCTC ATCGGGGGAC TCTGTTATTG GGCAGCTCTT CAGCTGTGAG 
ATGGAGAACT GCAGCCTCTG CCGCTGTGGC AGTGAGACCG TGCGAGCCTC ATCCACTCTG 
CTTTTCACAC TCTCCTACCC TGATGATAAA ACTGGGAAGA ACTATGACTT TGCTCAGGTG 
CTGAAGCGAA GCATCTGCCT GGACCAGAAT ACACAGGCCT GGTGTGACAC CTGTGAAAAG 
TACCAGCCCA CGATTCAGAC CCGCAACATC CGCCATCTGC CAGATATTCT TGTCATCAAT 
TGTGAGGTGA ACAGCTCAAA AGAGGCTGAT TTCTGGAGAA TGCAGGCTGA GGTTGCCTTC 
AAGATGGCAG TAAAGAAACA CGGTGGGGAA ATCTCCAAGA ACAAGGAATT TGCTTTGGCT 
GATTGGAAGG AACTAGGGAG TCCAGAGGGT GTGCTGGTGT GTCCCTCCAT TGAGGAGTTG 
AAGAACGTCT GGCTTCCTTT CTCCATTCGC ATGAAGATGA CCAAAAACAA AGGGCTGGAT 
GTTTGCAATT GGACTGATGG GGATGAGATG CAGTGGGGCC CAGCCAGGGC AGAGGAGGAG 
CATGGTGTCT ATGTGTATGA CCTGATGGCT ACTGTGGTAC ACATCCTGGA CTCACGCACA 
GGGGGCAGCC TGGTGGCTCA CATCAAAGTT GGAGAGACCT ACCACCAGCG CAAGGAGGGC 
GTTACTCACC AGCAGTGGTA TCTGTTCAAT GACTTTCTTA TTGAACCTAT TGATAAGCAT 
GAAGCTGTGC AGTTTGACAT GAATTGGAAA GTACCTGCAA TCCTTTATTA TGTCAAACGG 
AATCTCAATT CCAGATACAA CCTGAACATC AAGAACCCTA TTGAGGCAAG TGTCTTGCTG 
GCTGAAGCCT CGCTGGCACG GAAGCAGCGG AAAACACATA CTACCTTTAT TCCACTGATG 
CTGAATGAGA TGCCACAGAT TGGGGACCTG GTGGGTCTGG ATGCTGAGTT TGTCACCCTT 
AATGAGGAGG AAGCAGAGTT ACGCAGTGAT GGTACCAAGT CTACCATTAA ACCAAGCCAG 
ATGTCAGTAG CCAGGATTAC CTGTGTTCGG GGCCAGGGAC CCAATGAGGG TATCCCCTTC 
ATTGATGACT ACATCTCTAC CCAGGAGCAG GTGGTGGATT ACTTGACTCA ATACTCGGGT 
ATAAAGCCTG GTGACCTCGA TGCCAAAATT TCCTCCAAGC ACCTAACAAC TCTCAAGTCT 
ACCTACTTAA AGCTTCGTTT TCTCATTGAC ATTGGAGTCA AGTTTGTGGG TCATGGCCTG 
CAGAAGGACT TCCGGGTCAT CAACCTGATG GTGCCCAAGG ACCAAGTCCT TGACACTGTC 
TACCTGTTCC ATATGCCCCG AAAACGAATG ATTTCCCTGC GATTCCTTGC TTGGTACTTT 
CTGGACCTGA AGATTCAAGG GGAAACCCAT GACAGTATTG AGGATGCCCG CACAGCCCTT 
CAGCTGTACC GAAAGTATCT GGAGCTAAGC AAAAATGGCA CTGAGCCTGA GTCTTTCCAC 
AAGGTGCTCA AGGGTCTTTA TGAGAAGGGC AGAAAGATGG ACTGGAAGGT GCCTGAGCCT 
GAGGGCCAAA CAAGTCCCAA GAATGCAGCT GTCTTCTCCT CAGTGCTGGC GCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PAN2 ( NM_001166279.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001159751.1 Homo sapiens poly(A) specific ribonuclease subunit PAN2 (PAN2), transcript variant 2, mRNA.

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CloneID	OHu16348
Clone ID Related Accession (Same CDS sequence)	NM_001166279.1
Accession Version	NM_001166279.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3606bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-21
Organism	Homo sapiens(human)
Product	PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC025574.19, AB014610.2 and AC073896.41. Transcript Variant: This variant (2) differs in the 5' UTR and coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB014610.2, SRR1660809.139492.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACTTTG AGGGTCTGGA CCCTGGACTG GCAGAATATG CCCCAGCCAT GCATTCTGCC 
CTGGACCCTG TCTTGGATGC CCACCTGAAC CCAAGTCTGC TACAGAATGT GGAGCTGGAC 
CCAGAGGGAG TGGCCTTGGA GGCTCTTCCC GTCCAGGAAT CAGTGCACAT AATGGAAGGT 
GTCTACTCTG AATTGCACAG CGTGGTGGCT GAAGTGGGTG TACCTGTTTC CGTCTCCCAC 
TTTGACTTGC ACGAGGAGAT GCTGTGGGTG GGGAGCCACG GGGGCCATGC CACTTCATTT 
TTTGGCCCAG CCTTGGAGCG CTACTCATCC TTTCAAGTCA ATGGCAGTGA TGATATTCGG 
CAGATCCAGA GCCTGGAGAA TGGTATCCTT TTTCTCACCA AGAACAACCT CAAGTATATG 
GCCCGTGGGG GCCTCATTAT ATTTGATTAC CTGCTGGATG AGAATGAGGA TATGCACAGT 
CTCCTACTGA CTGACAGCAG CACTCTACTC GTTGGTGGGC TGCAGAATCA CATACTAGAG 
ATTGATCTTA ACACTGTCCA GGAGACTCAG AAGTATGCAG TAGAGACGCC TGGAGTCACC 
ATCATGAGAC AGACAAATCG CTTCTTCTTC TGCGGCCACA CGTCTGGCAA GGTTTCCCTG 
AGAGACCTCC GTACTTTTAA GGTGGAACAT GAGTTTGATG CCTTCTCAGG AAGTCTGTCA 
GACTTTGATG TGCATGGCAA CCTGCTAGCT GCCTGTGGCT TCTCCAGCCG CCTCACTGGC 
CTGGCCTGCG ACCGTTTCCT CAAGGTGTAT GATTTGCGCA TGATGCGTGC CATCACACCA 
CTTCAAGTAC ATGTGGATCC TGCCTTCTTG CGCTTCATTC CTACATATAC TTCTCGTCTT 
GCTATCATCT CTCAGTCAGG GCAGTGCCAA TTCTGTGAAC CCACAGGCCT GGCCAACCCA 
GCCGATATCT TTCATGTGAA TCCTGTGGGG CCTCTGCTAA TGACATTTGA TGTGTCAGCC 
AGCAAGCAGG CTCTGGCCTT TGGGGATTCT GAGGGCTGTG TGCACCTCTG GACTGATTCC 
CCGGAGCCTT CCTTCAACCC CTACTCCCGT GAGACTGAGT TTGCTTTGCC GTGTCTCGTG 
GACTCACTGC CTCCTCTGGA CTGGAGCCAG GACCTGCTGC CTCTTTCCCT CATCCCTGTC 
CCACTCACCA CTGACACACT TCTCTCTGAT TGGCCTGCTG CCAACTCTGC TCCAGCTCCC 
AGGCGAGCAC CACCCGTGGA TGCAGAGATT CTGCGCACCA TGAAGAAGGT GGGCTTCATT 
GGCTATGCGC CCAATCCCCG CACCAGGCTG CGCAATCAGA TACCCTACAG ACTCAAGGAG 
TCAGACAGTG AATTTGACAG CTTCAGCCAG GTCACTGAGT CACCAGTAGG ACGAGAAGAG 
GAACCACATC TCCACATGGT TTCTAAGAAA TACCGCAAGG TGACCATCAA ATATTCCAAG 
CTAGGGCTGG AGGACTTTGA CTTCAAACAC TACAATAAGA CCTTGTTTGC TGGATTAGAG 
CCCCACATTC CCAACGCCTA CTGTAACTGC ATGATCCAGG TGCTCTATTT CCTGGAGCCT 
GTACGCTGTC TAATTCAAAA CCACCTTTGC CAGAAGGAGT TCTGTCTGGC ATGTGAGCTG 
GGCTTCCTGT TTCACATGTT GGACCTCTCT CGTGGTGACC CTTGCCAGGG CAATAATTTT 
CTTCGGGCAT TCCGTACTAT TCCTGAGGCC TCAGCCCTCG GTCTAATCCT GGCTGACTCA 
GATGAGGCCT CAGGCAAGGG CAATCTGGCC AGGCTCATTC AGAGGTGGAA TCGCTTCATT 
CTCACTCAAC TGCATCAAGA TATGCAGGAG CTGGAAATAC CACAGGCTTA TCGAGGTGCT 
GGAGGCAGCT TTTGCTCATC GGGGGACTCT GTTATTGGGC AGCTCTTCAG CTGTGAGATG 
GAGAACTGCA GCCTCTGCCG CTGTGGCAGT GAGACCGTGC GAGCCTCATC CACTCTGCTT 
TTCACACTCT CCTACCCTGA TGGTAGCAAA AGTGATAAAA CTGGGAAGAA CTATGACTTT 
GCTCAGGTGC TGAAGCGAAG CATCTGCCTG GACCAGAATA CACAGGCCTG GTGTGACACC 
TGTGAAAAGT ACCAGCCCAC GATTCAGACC CGCAACATCC GCCATCTGCC AGATATTCTT 
GTCATCAATT GTGAGGTGAA CAGCTCAAAA GAGGCTGATT TCTGGAGAAT GCAGGCTGAG 
GTTGCCTTCA AGATGGCAGT AAAGAAACAC GGTGGGGAAA TCTCCAAGAA CAAGGAATTT 
GCTTTGGCTG ATTGGAAGGA ACTAGGGAGT CCAGAGGGTG TGCTGGTGTG TCCCTCCATT 
GAGGAGTTGA AGAACGTCTG GCTTCCTTTC TCCATTCGCA TGAAGATGAC CAAAAACAAA 
GGGCTGGATG TTTGCAATTG GACTGATGGG GATGAGATGC AGTGGGGCCC AGCCAGGGCA 
GAGGAGGAGC ATGGTGTCTA TGTGTATGAC CTGATGGCTA CTGTGGTACA CATCCTGGAC 
TCACGCACAG GGGGCAGCCT GGTGGCTCAC ATCAAAGTTG GAGAGACCTA CCACCAGCGC 
AAGGAGGGCG TTACTCACCA GCAGTGGTAT CTGTTCAATG ACTTTCTTAT TGAACCTATT 
GATAAGCATG AAGCTGTGCA GTTTGACATG AATTGGAAAG TACCTGCAAT CCTTTATTAT 
GTCAAACGGA ATCTCAATTC CAGATACAAC CTGAACATCA AGAACCCTAT TGAGGCAAGT 
GTCTTGCTGG CTGAAGCCTC GCTGGCACGG AAGCAGCGGA AAACACATAC TACCTTTATT 
CCACTGATGC TGAATGAGAT GCCACAGATT GGGGACCTGG TGGGTCTGGA TGCTGAGTTT 
GTCACCCTTA ATGAGGAGGA AGCAGAGTTA CGCAGTGATG GTACCAAGTC TACCATTAAA 
CCAAGCCAGA TGTCAGTAGC CAGGATTACC TGTGTTCGGG GCCAGGGACC CAATGAGGGT 
ATCCCCTTCA TTGATGACTA CATCTCTACC CAGGAGCAGG TGGTGGATTA CTTGACTCAA 
TACTCGGGTA TAAAGCCTGG TGACCTCGAT GCCAAAATTT CCTCCAAGCA CCTAACAACT 
CTCAAGTCTA CCTACTTAAA GCTTCGTTTT CTCATTGACA TTGGAGTCAA GTTTGTGGGT 
CATGGCCTGC AGAAGGACTT CCGGGTCATC AACCTGATGG TGCCCAAGGA CCAAGTCCTT 
GACACTGTCT ACCTGTTCCA TATGCCCCGA AAACGAATGA TTTCCCTGCG ATTCCTTGCT 
TGGTACTTTC TGGACCTGAA GATTCAAGGG GAAACCCATG ACAGTATTGA GGATGCCCGC 
ACAGCCCTTC AGCTGTACCG AAAGTATCTG GAGCTAAGCA AAAATGGCAC TGAGCCTGAG 
TCTTTCCACA AGGTGCTCAA GGGTCTTTAT GAGAAGGGCA GAAAGATGGA CTGGAAGGTG 
CCTGAGCCTG AGGGCCAAAC AAGTCCCAAG AATGCAGCTG TCTTCTCCTC AGTGCTGGCG 
CTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001159751.1
CDS	307..3912
Translation	MNFEGLDPGLAEYAPAMHSALDPVLDAHLNPSLLQNVELDPEGVALEALPVQESVHIMEGVYSELHSVVAEVGVPVSVSHFDLHEEMLWVGSHGGHATSFFGPALERYSSFQVNGSDDIRQIQSLENGILFLTKNNLKYMARGGLIIFDYLLDENEDMHSLLLTDSSTLLVGGLQNHILEIDLNTVQETQKYAVETPGVTIMRQTNRFFFCGHTSGKVSLRDLRTFKVEHEFDAFSGSLSDFDVHGNLLAACGFSSRLTGLACDRFLKVYDLRMMRAITPLQVHVDPAFLRFIPTYTSRLAIISQSGQCQFCEPTGLANPADIFHVNPVGPLLMTFDVSASKQALAFGDSEGCVHLWTDSPEPSFNPYSRETEFALPCLVDSLPPLDWSQDLLPLSLIPVPLTTDTLLSDWPAANSAPAPRRAPPVDAEILRTMKKVGFIGYAPNPRTRLRNQIPYRLKESDSEFDSFSQVTESPVGREEEPHLHMVSKKYRKVTIKYSKLGLEDFDFKHYNKTLFAGLEPHIPNAYCNCMIQVLYFLEPVRCLIQNHLCQKEFCLACELGFLFHMLDLSRGDPCQGNNFLRAFRTIPEASALGLILADSDEASGKGNLARLIQRWNRFILTQLHQDMQELEIPQAYRGAGGSFCSSGDSVIGQLFSCEMENCSLCRCGSETVRASSTLLFTLSYPDGSKSDKTGKNYDFAQVLKRSICLDQNTQAWCDTCEKYQPTIQTRNIRHLPDILVINCEVNSSKEADFWRMQAEVAFKMAVKKHGGEISKNKEFALADWKELGSPEGVLVCPSIEELKNVWLPFSIRMKMTKNKGLDVCNWTDGDEMQWGPARAEEEHGVYVYDLMATVVHILDSRTGGSLVAHIKVGETYHQRKEGVTHQQWYLFNDFLIEPIDKHEAVQFDMNWKVPAILYYVKRNLNSRYNLNIKNPIEASVLLAEASLARKQRKTHTTFIPLMLNEMPQIGDLVGLDAEFVTLNEEEAELRSDGTKSTIKPSQMSVARITCVRGQGPNEGIPFIDDYISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYLKLRFLIDIGVKFVGHGLQKDFRVINLMVPKDQVLDTVYLFHMPRKRMISLRFLAWYFLDLKIQGETHDSIEDARTALQLYRKYLELSKNGTEPESFHKVLKGLYEKGRKMDWKVPEPEGQTSPKNAAVFSSVLAL

Target ORF information:

RefSeq Version	NM_001166279.1
Organism	Homo sapiens(human)
Definition	Homo sapiens poly(A) specific ribonuclease subunit PAN2 (PAN2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001166279.1

ORF Insert Sequence:

ATGAACTTTG AGGGTCTGGA CCCTGGACTG GCAGAATATG CCCCAGCCAT GCATTCTGCC 
CTGGACCCTG TCTTGGATGC CCACCTGAAC CCAAGTCTGC TACAGAATGT GGAGCTGGAC 
CCAGAGGGAG TGGCCTTGGA GGCTCTTCCC GTCCAGGAAT CAGTGCACAT AATGGAAGGT 
GTCTACTCTG AATTGCACAG CGTGGTGGCT GAAGTGGGTG TACCTGTTTC CGTCTCCCAC 
TTTGACTTGC ACGAGGAGAT GCTGTGGGTG GGGAGCCACG GGGGCCATGC CACTTCATTT 
TTTGGCCCAG CCTTGGAGCG CTACTCATCC TTTCAAGTCA ATGGCAGTGA TGATATTCGG 
CAGATCCAGA GCCTGGAGAA TGGTATCCTT TTTCTCACCA AGAACAACCT CAAGTATATG 
GCCCGTGGGG GCCTCATTAT ATTTGATTAC CTGCTGGATG AGAATGAGGA TATGCACAGT 
CTCCTACTGA CTGACAGCAG CACTCTACTC GTTGGTGGGC TGCAGAATCA CATACTAGAG 
ATTGATCTTA ACACTGTCCA GGAGACTCAG AAGTATGCAG TAGAGACGCC TGGAGTCACC 
ATCATGAGAC AGACAAATCG CTTCTTCTTC TGCGGCCACA CGTCTGGCAA GGTTTCCCTG 
AGAGACCTCC GTACTTTTAA GGTGGAACAT GAGTTTGATG CCTTCTCAGG AAGTCTGTCA 
GACTTTGATG TGCATGGCAA CCTGCTAGCT GCCTGTGGCT TCTCCAGCCG CCTCACTGGC 
CTGGCCTGCG ACCGTTTCCT CAAGGTGTAT GATTTGCGCA TGATGCGTGC CATCACACCA 
CTTCAAGTAC ATGTGGATCC TGCCTTCTTG CGCTTCATTC CTACATATAC TTCTCGTCTT 
GCTATCATCT CTCAGTCAGG GCAGTGCCAA TTCTGTGAAC CCACAGGCCT GGCCAACCCA 
GCCGATATCT TTCATGTGAA TCCTGTGGGG CCTCTGCTAA TGACATTTGA TGTGTCAGCC 
AGCAAGCAGG CTCTGGCCTT TGGGGATTCT GAGGGCTGTG TGCACCTCTG GACTGATTCC 
CCGGAGCCTT CCTTCAACCC CTACTCCCGT GAGACTGAGT TTGCTTTGCC GTGTCTCGTG 
GACTCACTGC CTCCTCTGGA CTGGAGCCAG GACCTGCTGC CTCTTTCCCT CATCCCTGTC 
CCACTCACCA CTGACACACT TCTCTCTGAT TGGCCTGCTG CCAACTCTGC TCCAGCTCCC 
AGGCGAGCAC CACCCGTGGA TGCAGAGATT CTGCGCACCA TGAAGAAGGT GGGCTTCATT 
GGCTATGCGC CCAATCCCCG CACCAGGCTG CGCAATCAGA TACCCTACAG ACTCAAGGAG 
TCAGACAGTG AATTTGACAG CTTCAGCCAG GTCACTGAGT CACCAGTAGG ACGAGAAGAG 
GAACCACATC TCCACATGGT TTCTAAGAAA TACCGCAAGG TGACCATCAA ATATTCCAAG 
CTAGGGCTGG AGGACTTTGA CTTCAAACAC TACAATAAGA CCTTGTTTGC TGGATTAGAG 
CCCCACATTC CCAACGCCTA CTGTAACTGC ATGATCCAGG TGCTCTATTT CCTGGAGCCT 
GTACGCTGTC TAATTCAAAA CCACCTTTGC CAGAAGGAGT TCTGTCTGGC ATGTGAGCTG 
GGCTTCCTGT TTCACATGTT GGACCTCTCT CGTGGTGACC CTTGCCAGGG CAATAATTTT 
CTTCGGGCAT TCCGTACTAT TCCTGAGGCC TCAGCCCTCG GTCTAATCCT GGCTGACTCA 
GATGAGGCCT CAGGCAAGGG CAATCTGGCC AGGCTCATTC AGAGGTGGAA TCGCTTCATT 
CTCACTCAAC TGCATCAAGA TATGCAGGAG CTGGAAATAC CACAGGCTTA TCGAGGTGCT 
GGAGGCAGCT TTTGCTCATC GGGGGACTCT GTTATTGGGC AGCTCTTCAG CTGTGAGATG 
GAGAACTGCA GCCTCTGCCG CTGTGGCAGT GAGACCGTGC GAGCCTCATC CACTCTGCTT 
TTCACACTCT CCTACCCTGA TGGTAGCAAA AGTGATAAAA CTGGGAAGAA CTATGACTTT 
GCTCAGGTGC TGAAGCGAAG CATCTGCCTG GACCAGAATA CACAGGCCTG GTGTGACACC 
TGTGAAAAGT ACCAGCCCAC GATTCAGACC CGCAACATCC GCCATCTGCC AGATATTCTT 
GTCATCAATT GTGAGGTGAA CAGCTCAAAA GAGGCTGATT TCTGGAGAAT GCAGGCTGAG 
GTTGCCTTCA AGATGGCAGT AAAGAAACAC GGTGGGGAAA TCTCCAAGAA CAAGGAATTT 
GCTTTGGCTG ATTGGAAGGA ACTAGGGAGT CCAGAGGGTG TGCTGGTGTG TCCCTCCATT 
GAGGAGTTGA AGAACGTCTG GCTTCCTTTC TCCATTCGCA TGAAGATGAC CAAAAACAAA 
GGGCTGGATG TTTGCAATTG GACTGATGGG GATGAGATGC AGTGGGGCCC AGCCAGGGCA 
GAGGAGGAGC ATGGTGTCTA TGTGTATGAC CTGATGGCTA CTGTGGTACA CATCCTGGAC 
TCACGCACAG GGGGCAGCCT GGTGGCTCAC ATCAAAGTTG GAGAGACCTA CCACCAGCGC 
AAGGAGGGCG TTACTCACCA GCAGTGGTAT CTGTTCAATG ACTTTCTTAT TGAACCTATT 
GATAAGCATG AAGCTGTGCA GTTTGACATG AATTGGAAAG TACCTGCAAT CCTTTATTAT 
GTCAAACGGA ATCTCAATTC CAGATACAAC CTGAACATCA AGAACCCTAT TGAGGCAAGT 
GTCTTGCTGG CTGAAGCCTC GCTGGCACGG AAGCAGCGGA AAACACATAC TACCTTTATT 
CCACTGATGC TGAATGAGAT GCCACAGATT GGGGACCTGG TGGGTCTGGA TGCTGAGTTT 
GTCACCCTTA ATGAGGAGGA AGCAGAGTTA CGCAGTGATG GTACCAAGTC TACCATTAAA 
CCAAGCCAGA TGTCAGTAGC CAGGATTACC TGTGTTCGGG GCCAGGGACC CAATGAGGGT 
ATCCCCTTCA TTGATGACTA CATCTCTACC CAGGAGCAGG TGGTGGATTA CTTGACTCAA 
TACTCGGGTA TAAAGCCTGG TGACCTCGAT GCCAAAATTT CCTCCAAGCA CCTAACAACT 
CTCAAGTCTA CCTACTTAAA GCTTCGTTTT CTCATTGACA TTGGAGTCAA GTTTGTGGGT 
CATGGCCTGC AGAAGGACTT CCGGGTCATC AACCTGATGG TGCCCAAGGA CCAAGTCCTT 
GACACTGTCT ACCTGTTCCA TATGCCCCGA AAACGAATGA TTTCCCTGCG ATTCCTTGCT 
TGGTACTTTC TGGACCTGAA GATTCAAGGG GAAACCCATG ACAGTATTGA GGATGCCCGC 
ACAGCCCTTC AGCTGTACCG AAAGTATCTG GAGCTAAGCA AAAATGGCAC TGAGCCTGAG 
TCTTTCCACA AGGTGCTCAA GGGTCTTTAT GAGAAGGGCA GAAAGATGGA CTGGAAGGTG 
CCTGAGCCTG AGGGCCAAAC AAGTCCCAAG AATGCAGCTG TCTTCTCCTC AGTGCTGGCG 
CTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.
Human molecular genetics24(6)1791-800(2015 Mar)
He M,Xu M,Zhang B,Liang J,Chen P,Lee JY,Johnson TA,Li H,Yang X,Dai J,Liang L,Gui L,Qi Q,Huang J,Li Y,Adair LS,Aung T,Cai Q,Cheng CY,Cho MC,Cho YS,Chu M,Cui B,Gao YT,Go MJ,Gu D,Gu W,Guo H,Hao Y,Hong J,Hu Z,Hu Y,Huang J,Hwang JY,Ikram MK,Jin G,Kang DH,Khor CC,Kim BJ,Kim HT,Kubo M,Lee J,Lee J,Lee NR,Li R,Li J,Liu J,Longe J,Lu W,Lu X,Miao X,Okada Y,Ong RT,Qiu G,Seielstad M,Sim X,Song H,Takeuchi F,Tanaka T,Taylor PR,Wang L,Wang W,Wang Y,Wu C,Wu Y,Xiang YB,Yamamoto K,Yang H,Liao M,Yokota M,Young T,Zhang X,Kato N,Wang QK,Zheng W,Hu FB,Lin D,Shen H,Teo YY,Mo Z,Wong TY,Lin X,Mohlke KL,Ning G,Tsunoda T,Han BG,Shu XO,Tai ES,Wu T,Qi L

Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.
American journal of human genetics93(2)264-77(2013 Aug)
Cheng CY,Schache M,Ikram MK,Young TL,Guggenheim JA,Vitart V,MacGregor S,Verhoeven VJ,Barathi VA,Liao J,Hysi PG,Bailey-Wilson JE,St Pourcain B,Kemp JP,McMahon G,Timpson NJ,Evans DM,Montgomery GW,Mishra A,Wang YX,Wang JJ,Rochtchina E,Polasek O,Wright AF,Amin N,van Leeuwen EM,Wilson JF,Pennell CE,van Duijn CM,de Jong PT,Vingerling JR,Zhou X,Chen P,Li R,Tay WT,Zheng Y,Chew M,,Burdon KP,Craig JE,Iyengar SK,Igo RP Jr,Lass JH Jr,,Chew EY,Haller T,Mihailov E,Metspalu A,Wedenoja J,Simpson CL,Wojciechowski R,H?hn R,Mirshahi A,Zeller T,Pfeiffer N,Lackner KJ,,Bettecken T,Meitinger T,Oexle K,Pirastu M,Portas L,Nag A,Williams KM,Yonova-Doing E,Klein R,Klein BE,Hosseini SM,Paterson AD,,Makela KM,Lehtimaki T,Kahonen M,Raitakari O,Yoshimura N,Matsuda F,Chen LJ,Pang CP,Yip SP,Yap MK,Meguro A,Mizuki N,Inoko H,Foster PJ,Zhao JH,Vithana E,Tai ES,Fan Q,Xu L,Campbell H,Fleck B,Rudan I,Aung T,Hofman A,Uitterlinden AG,Bencic G,Khor CC,Forward H,P?rssinen O,Mitchell P,Rivadeneira F,Hewitt AW,Williams C,Oostra BA,Teo YY,Hammond CJ,Stambolian D,Mackey DA,Klaver CC,Wong TY,Saw SM,Baird PN

The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability.
The Biochemical journal451(2)185-94(2013 Apr)
Bett JS,Ibrahim AF,Garg AK,Kelly V,Pedrioli P,Rocha S,Hay RT

miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOT.
Nature structural & molecular biology18(11)1211-7(2011 Oct)
Fabian MR,Cieplak MK,Frank F,Morita M,Green J,Srikumar T,Nagar B,Yamamoto T,Raught B,Duchaine TF,Sonenberg N

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PAN2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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