NFE2L3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NFE2L3
Entrez Gene ID	9603
Full Name	nuclear factor, erythroid 2 like 3
Synonyms	NRF3
General protein information	Preferred Names nuclear factor, erythroid 2 like 3 Names nuclear factor erythroid 2-related factor 3 NF-E2-related factor 3 NFE2-related factor 3 nuclear factor, erythroid derived 2, like 3 nuclear factor-erythroid 2 p45-related factor 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7p15.2
Summary	This gene encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18. [provided by RefSeq, Mar 2009].
Disorder MIM:	604135

mRNA and Protein(s)

mRNA	Protein	Name
NM_004289.6	NP_004280.5	nuclear factor erythroid 2-related factor 3
NM_004289.7	NP_004280.5	nuclear factor erythroid 2-related factor 3

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Nfe2l3	NP_035033.1
Canis lupus familiaris (dog)	NFE2L3	XP_539481.2
Rattus norvegicus (Norway rat)	Nfe2l3	XP_231763.6
	NFE2L3	XP_001094650.1
Homo sapiens (human)	NFE2L3	NP_004280.5
Xenopus tropicalis (tropical clawed frog)	nfe2l3	XP_002933432.1
Pan troglodytes (chimpanzee)	NFE2L3	XP_519002.2
Bos taurus (cattle)	NFE2L3	NP_001071367.2

Gene Ontology
Bibliography

Related articles in PubMed

Multiple regulatory mechanisms of the biological function of NRF3 (NFE2L3) control cancer cell proliferation.
Chowdhury AMMA, Katoh H, Hatanaka A, Iwanari H, Nakamura N, Hamakubo T, Natsume T, Waku T, Kobayashi A
Scientific reports7(1)12494(2017 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

findings reveal FBW7 and GSK3 as novel regulators of the NFE2L3 transcription factor and a potential mechanism by which FBW7 might regulate detoxification and the cellular response to stress
Title: Stringent Control of NFE2L3 (Nuclear Factor, Erythroid 2-Like 3; NRF3) Protein Degradation by FBW7 (F-box/WD Repeat-containing Protein 7) and Glycogen Synthase Kinase 3 (GSK3).

17beta-Estradiol treatment significantly increased but VC or Res decreased Nrf3 mRNA and protein expression levels.
Title: Natural antioxidants exhibit chemopreventive characteristics through the regulation of CNC b-Zip transcription factors in estrogen-induced breast carcinogenesis.

Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
Title: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

The following NFE2L3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NFE2L3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu13712	NM_004289.7 Latest version!	Homo sapiens nuclear factor, erythroid 2 like 3 (NFE2L3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
View Old Accession Versions >>
OHu13712	NM_004289.6	Homo sapiens nuclear factor, erythroid 2 like 3 (NFE2L3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NFE2L3 ( NM_004289.7 ) cDNA ORF clone, Homo sapiens(human) -> NP_004280.5 Homo sapiens nuclear factor, erythroid 2 like 3 (NFE2L3), mRNA.

Price & Availability↑

CloneID	OHu13712
Clone ID Related Accession (Same CDS sequence)	NM_004289.6 , NM_004289.7
Accession Version	NM_004289.7 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2085bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	nuclear factor erythroid 2-related factor 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC004520.2, BX396198.2, AF134891.1, BC056142.1 and AA603252.1. On Nov 23, 2018 this sequence version replaced NM_004289.6. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC068455.1, AF134891.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000056233.4/ ENSP00000056233.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAGCACC TGAAGCGGTG GTGGTCGGCC GGCGGCGGCC TCCTGCACCT CACCCTCCTG 
CTGAGCTTGG CGGGGCTCCG CGTAGACCTA GATCTTTACC TGCTGCTGCC GCCGCCCACC 
CTGCTGCAGG ACGAGCTGCT GTTCCTGGGC GGCCCGGCCA GCTCCGCCTA CGCGCTCAGC 
CCCTTCTCGG CCTCGGGAGG GTGGGGGCGC GCGGGCCACT TGCACCCCAA GGGCCGGGAG 
CTGGACCCTG CCGCGCCGCC CGAGGGCCAG CTGCTCCGGG AGGTGCGCGC GCTCGGGGTC 
CCCTTCGTCC CTCGCACCAG CGTGGATGCA TGGCTGGTGC ACAGCGTGGC TGCCGGGAGC 
GCGGACGAGG CCCACGGGCT GCTCGGCGCC GCCGCCGCCT CGTCCACCGG AGGAGCCGGC 
GCCAGCGTGG ACGGCGGCAG CCAGGCTGTG CAGGGGGGCG GCGGGGACCC CCGAGCGGCT 
CGGAGTGGCC CCTTGGACGC CGGGGAAGAG GAGAAGGCAC CCGCGGAACC GACGGCTCAG 
GTGCCGGACG CTGGCGGATG TGCGAGCGAG GAGAATGGGG TACTAAGAGA AAAGCACGAA 
GCTGTGGATC ATAGTTCCCA GCATGAGGAA AATGAAGAAA GGGTGTCAGC CCAGAAGGAG 
AACTCACTTC AGCAGAATGA TGATGATGAA AACAAAATAG CAGAGAAACC TGACTGGGAG 
GCAGAAAAGA CCACTGAATC TAGAAATGAG AGACATCTGA ATGGGACAGA TACTTCTTTC 
TCTCTGGAAG ACTTATTCCA GTTGCTTTCA TCACAGCCTG AAAATTCACT GGAGGGCATC 
TCATTGGGAG ATATTCCTCT TCCAGGCAGT ATCAGTGATG GCATGAATTC TTCAGCACAT 
TATCATGTAA ACTTCAGCCA GGCTATAAGT CAGGATGTGA ATCTTCATGA GGCCATCTTG 
CTTTGTCCCA ACAATACATT TAGAAGAGAT CCAACAGCAA GGACTTCACA GTCACAAGAA 
CCATTTCTGC AGTTAAATTC TCATACCACC AATCCTGAGC AAACCCTTCC TGGAACTAAT 
TTGACAGGAT TTCTTTCACC GGTTGACAAT CATATGAGGA ATCTAACAAG CCAAGACCTA 
CTGTATGACC TTGACATAAA TATATTTGAT GAGATAAACT TAATGTCATT GGCCACAGAA 
GACAACTTTG ATCCAATCGA TGTTTCTCAG CTTTTTGATG AACCAGATTC TGATTCTGGC 
CTTTCTTTAG ATTCAAGTCA CAATAATACC TCTGTCATCA AGTCTAATTC CTCTCACTCT 
GTGTGTGATG AAGGTGCTAT AGGTTATTGC ACTGACCATG AATCTAGTTC CCATCATGAC 
TTAGAAGGTG CTGTAGGTGG CTACTACCCA GAACCCAGTA AGCTTTGTCA CTTGGATCAA 
AGTGATTCTG ATTTCCATGG AGATCTTACA TTTCAACACG TATTTCATAA CCACACTTAC 
CACTTACAGC CAACTGCACC AGAATCTACT TCTGAACCTT TTCCGTGGCC TGGGAAGTCA 
CAGAAGATAA GGAGTAGATA CCTTGAAGAC ACAGATAGAA ACTTGAGCCG TGATGAACAG 
CGTGCTAAAG CTTTGCATAT CCCTTTTTCT GTAGATGAAA TTGTCGGCAT GCCTGTTGAT 
TCTTTCAATA GCATGTTAAG TAGATATTAT CTGACAGACC TACAAGTCTC ACTTATCCGT 
GACATCAGAC GAAGAGGGAA AAATAAAGTT GCTGCGCAGA ACTGTCGTAA ACGCAAATTG 
GACATAATTT TGAATTTAGA AGATGATGTA TGTAACTTGC AAGCAAAGAA GGAAACTCTT 
AAGAGAGAGC AAGCACAATG TAACAAAGCT ATTAACATAA TGAAACAGAA ACTGCATGAC 
CTTTATCATG ATATTTTTAG TAGATTAAGA GATGACCAAG GTAGGCCAGT CAATCCCAAC 
CACTATGCTC TCCAGTGTAC CCATGATGGA AGTATCTTGA TAGTACCCAA AGAACTGGTG 
GCCTCAGGCC ACAAAAAGGA AACCCAAAAG GGAAAGAGAA AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004280.5
CDS	302..2386
Translation	MKHLKRWWSAGGGLLHLTLLLSLAGLRVDLDLYLLLPPPTLLQDELLFLGGPASSAYALSPFSASGGWGRAGHLHPKGRELDPAAPPEGQLLREVRALGVPFVPRTSVDAWLVHSVAAGSADEAHGLLGAAAASSTGGAGASVDGGSQAVQGGGGDPRAARSGPLDAGEEEKAPAEPTAQVPDAGGCASEENGVLREKHEAVDHSSQHEENEERVSAQKENSLQQNDDDENKIAEKPDWEAEKTTESRNERHLNGTDTSFSLEDLFQLLSSQPENSLEGISLGDIPLPGSISDGMNSSAHYHVNFSQAISQDVNLHEAILLCPNNTFRRDPTARTSQSQEPFLQLNSHTTNPEQTLPGTNLTGFLSPVDNHMRNLTSQDLLYDLDINIFDEINLMSLATEDNFDPIDVSQLFDEPDSDSGLSLDSSHNNTSVIKSNSSHSVCDEGAIGYCTDHESSSHHDLEGAVGGYYPEPSKLCHLDQSDSDFHGDLTFQHVFHNHTYHLQPTAPESTSEPFPWPGKSQKIRSRYLEDTDRNLSRDEQRAKALHIPFSVDEIVGMPVDSFNSMLSRYYLTDLQVSLIRDIRRRGKNKVAAQNCRKRKLDIILNLEDDVCNLQAKKETLKREQAQCNKAINIMKQKLHDLYHDIFSRLRDDQGRPVNPNHYALQCTHDGSILIVPKELVASGHKKETQKGKRK

Target ORF information:

RefSeq Version	NM_004289.7
Organism	Homo sapiens(human)
Definition	Homo sapiens nuclear factor, erythroid 2 like 3 (NFE2L3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004289.7

ORF Insert Sequence:

ATGAAGCACC TGAAGCGGTG GTGGTCGGCC GGCGGCGGCC TCCTGCACCT CACCCTCCTG 
CTGAGCTTGG CGGGGCTCCG CGTAGACCTA GATCTTTACC TGCTGCTGCC GCCGCCCACC 
CTGCTGCAGG ACGAGCTGCT GTTCCTGGGC GGCCCGGCCA GCTCCGCCTA CGCGCTCAGC 
CCCTTCTCGG CCTCGGGAGG GTGGGGGCGC GCGGGCCACT TGCACCCCAA GGGCCGGGAG 
CTGGACCCTG CCGCGCCGCC CGAGGGCCAG CTGCTCCGGG AGGTGCGCGC GCTCGGGGTC 
CCCTTCGTCC CTCGCACCAG CGTGGATGCA TGGCTGGTGC ACAGCGTGGC TGCCGGGAGC 
GCGGACGAGG CCCACGGGCT GCTCGGCGCC GCCGCCGCCT CGTCCACCGG AGGAGCCGGC 
GCCAGCGTGG ACGGCGGCAG CCAGGCTGTG CAGGGGGGCG GCGGGGACCC CCGAGCGGCT 
CGGAGTGGCC CCTTGGACGC CGGGGAAGAG GAGAAGGCAC CCGCGGAACC GACGGCTCAG 
GTGCCGGACG CTGGCGGATG TGCGAGCGAG GAGAATGGGG TACTAAGAGA AAAGCACGAA 
GCTGTGGATC ATAGTTCCCA GCATGAGGAA AATGAAGAAA GGGTGTCAGC CCAGAAGGAG 
AACTCACTTC AGCAGAATGA TGATGATGAA AACAAAATAG CAGAGAAACC TGACTGGGAG 
GCAGAAAAGA CCACTGAATC TAGAAATGAG AGACATCTGA ATGGGACAGA TACTTCTTTC 
TCTCTGGAAG ACTTATTCCA GTTGCTTTCA TCACAGCCTG AAAATTCACT GGAGGGCATC 
TCATTGGGAG ATATTCCTCT TCCAGGCAGT ATCAGTGATG GCATGAATTC TTCAGCACAT 
TATCATGTAA ACTTCAGCCA GGCTATAAGT CAGGATGTGA ATCTTCATGA GGCCATCTTG 
CTTTGTCCCA ACAATACATT TAGAAGAGAT CCAACAGCAA GGACTTCACA GTCACAAGAA 
CCATTTCTGC AGTTAAATTC TCATACCACC AATCCTGAGC AAACCCTTCC TGGAACTAAT 
TTGACAGGAT TTCTTTCACC GGTTGACAAT CATATGAGGA ATCTAACAAG CCAAGACCTA 
CTGTATGACC TTGACATAAA TATATTTGAT GAGATAAACT TAATGTCATT GGCCACAGAA 
GACAACTTTG ATCCAATCGA TGTTTCTCAG CTTTTTGATG AACCAGATTC TGATTCTGGC 
CTTTCTTTAG ATTCAAGTCA CAATAATACC TCTGTCATCA AGTCTAATTC CTCTCACTCT 
GTGTGTGATG AAGGTGCTAT AGGTTATTGC ACTGACCATG AATCTAGTTC CCATCATGAC 
TTAGAAGGTG CTGTAGGTGG CTACTACCCA GAACCCAGTA AGCTTTGTCA CTTGGATCAA 
AGTGATTCTG ATTTCCATGG AGATCTTACA TTTCAACACG TATTTCATAA CCACACTTAC 
CACTTACAGC CAACTGCACC AGAATCTACT TCTGAACCTT TTCCGTGGCC TGGGAAGTCA 
CAGAAGATAA GGAGTAGATA CCTTGAAGAC ACAGATAGAA ACTTGAGCCG TGATGAACAG 
CGTGCTAAAG CTTTGCATAT CCCTTTTTCT GTAGATGAAA TTGTCGGCAT GCCTGTTGAT 
TCTTTCAATA GCATGTTAAG TAGATATTAT CTGACAGACC TACAAGTCTC ACTTATCCGT 
GACATCAGAC GAAGAGGGAA AAATAAAGTT GCTGCGCAGA ACTGTCGTAA ACGCAAATTG 
GACATAATTT TGAATTTAGA AGATGATGTA TGTAACTTGC AAGCAAAGAA GGAAACTCTT 
AAGAGAGAGC AAGCACAATG TAACAAAGCT ATTAACATAA TGAAACAGAA ACTGCATGAC 
CTTTATCATG ATATTTTTAG TAGATTAAGA GATGACCAAG GTAGGCCAGT CAATCCCAAC 
CACTATGCTC TCCAGTGTAC CCATGATGGA AGTATCTTGA TAGTACCCAA AGAACTGGTG 
GCCTCAGGCC ACAAAAAGGA AACCCAAAAG GGAAAGAGAA AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NFE2L3 ( NM_004289.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_004280.5 Homo sapiens nuclear factor, erythroid 2 like 3 (NFE2L3), mRNA.

Price & Availability↑

CloneID	OHu13712
Clone ID Related Accession (Same CDS sequence)	NM_004289.6 , NM_004289.7
Accession Version	NM_004289.6	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2085bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	nuclear factor erythroid 2-related factor 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX396198.2, AF134891.1, BC056142.1 and AA603252.1. On Mar 28, 2009 this sequence version replaced NM_004289.5. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC068455.1, AF134891.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGCACC TGAAGCGGTG GTGGTCGGCC GGCGGCGGCC TCCTGCACCT CACCCTCCTG 
CTGAGCTTGG CGGGGCTCCG CGTAGACCTA GATCTTTACC TGCTGCTGCC GCCGCCCACC 
CTGCTGCAGG ACGAGCTGCT GTTCCTGGGC GGCCCGGCCA GCTCCGCCTA CGCGCTCAGC 
CCCTTCTCGG CCTCGGGAGG GTGGGGGCGC GCGGGCCACT TGCACCCCAA GGGCCGGGAG 
CTGGACCCTG CCGCGCCGCC CGAGGGCCAG CTGCTCCGGG AGGTGCGCGC GCTCGGGGTC 
CCCTTCGTCC CTCGCACCAG CGTGGATGCA TGGCTGGTGC ACAGCGTGGC TGCCGGGAGC 
GCGGACGAGG CCCACGGGCT GCTCGGCGCC GCCGCCGCCT CGTCCACCGG AGGAGCCGGC 
GCCAGCGTGG ACGGCGGCAG CCAGGCTGTG CAGGGGGGCG GCGGGGACCC CCGAGCGGCT 
CGGAGTGGCC CCTTGGACGC CGGGGAAGAG GAGAAGGCAC CCGCGGAACC GACGGCTCAG 
GTGCCGGACG CTGGCGGATG TGCGAGCGAG GAGAATGGGG TACTAAGAGA AAAGCACGAA 
GCTGTGGATC ATAGTTCCCA GCATGAGGAA AATGAAGAAA GGGTGTCAGC CCAGAAGGAG 
AACTCACTTC AGCAGAATGA TGATGATGAA AACAAAATAG CAGAGAAACC TGACTGGGAG 
GCAGAAAAGA CCACTGAATC TAGAAATGAG AGACATCTGA ATGGGACAGA TACTTCTTTC 
TCTCTGGAAG ACTTATTCCA GTTGCTTTCA TCACAGCCTG AAAATTCACT GGAGGGCATC 
TCATTGGGAG ATATTCCTCT TCCAGGCAGT ATCAGTGATG GCATGAATTC TTCAGCACAT 
TATCATGTAA ACTTCAGCCA GGCTATAAGT CAGGATGTGA ATCTTCATGA GGCCATCTTG 
CTTTGTCCCA ACAATACATT TAGAAGAGAT CCAACAGCAA GGACTTCACA GTCACAAGAA 
CCATTTCTGC AGTTAAATTC TCATACCACC AATCCTGAGC AAACCCTTCC TGGAACTAAT 
TTGACAGGAT TTCTTTCACC GGTTGACAAT CATATGAGGA ATCTAACAAG CCAAGACCTA 
CTGTATGACC TTGACATAAA TATATTTGAT GAGATAAACT TAATGTCATT GGCCACAGAA 
GACAACTTTG ATCCAATCGA TGTTTCTCAG CTTTTTGATG AACCAGATTC TGATTCTGGC 
CTTTCTTTAG ATTCAAGTCA CAATAATACC TCTGTCATCA AGTCTAATTC CTCTCACTCT 
GTGTGTGATG AAGGTGCTAT AGGTTATTGC ACTGACCATG AATCTAGTTC CCATCATGAC 
TTAGAAGGTG CTGTAGGTGG CTACTACCCA GAACCCAGTA AGCTTTGTCA CTTGGATCAA 
AGTGATTCTG ATTTCCATGG AGATCTTACA TTTCAACACG TATTTCATAA CCACACTTAC 
CACTTACAGC CAACTGCACC AGAATCTACT TCTGAACCTT TTCCGTGGCC TGGGAAGTCA 
CAGAAGATAA GGAGTAGATA CCTTGAAGAC ACAGATAGAA ACTTGAGCCG TGATGAACAG 
CGTGCTAAAG CTTTGCATAT CCCTTTTTCT GTAGATGAAA TTGTCGGCAT GCCTGTTGAT 
TCTTTCAATA GCATGTTAAG TAGATATTAT CTGACAGACC TACAAGTCTC ACTTATCCGT 
GACATCAGAC GAAGAGGGAA AAATAAAGTT GCTGCGCAGA ACTGTCGTAA ACGCAAATTG 
GACATAATTT TGAATTTAGA AGATGATGTA TGTAACTTGC AAGCAAAGAA GGAAACTCTT 
AAGAGAGAGC AAGCACAATG TAACAAAGCT ATTAACATAA TGAAACAGAA ACTGCATGAC 
CTTTATCATG ATATTTTTAG TAGATTAAGA GATGACCAAG GTAGGCCAGT CAATCCCAAC 
CACTATGCTC TCCAGTGTAC CCATGATGGA AGTATCTTGA TAGTACCCAA AGAACTGGTG 
GCCTCAGGCC ACAAAAAGGA AACCCAAAAG GGAAAGAGAA AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004280.5
CDS	273..2357
Translation	MKHLKRWWSAGGGLLHLTLLLSLAGLRVDLDLYLLLPPPTLLQDELLFLGGPASSAYALSPFSASGGWGRAGHLHPKGRELDPAAPPEGQLLREVRALGVPFVPRTSVDAWLVHSVAAGSADEAHGLLGAAAASSTGGAGASVDGGSQAVQGGGGDPRAARSGPLDAGEEEKAPAEPTAQVPDAGGCASEENGVLREKHEAVDHSSQHEENEERVSAQKENSLQQNDDDENKIAEKPDWEAEKTTESRNERHLNGTDTSFSLEDLFQLLSSQPENSLEGISLGDIPLPGSISDGMNSSAHYHVNFSQAISQDVNLHEAILLCPNNTFRRDPTARTSQSQEPFLQLNSHTTNPEQTLPGTNLTGFLSPVDNHMRNLTSQDLLYDLDINIFDEINLMSLATEDNFDPIDVSQLFDEPDSDSGLSLDSSHNNTSVIKSNSSHSVCDEGAIGYCTDHESSSHHDLEGAVGGYYPEPSKLCHLDQSDSDFHGDLTFQHVFHNHTYHLQPTAPESTSEPFPWPGKSQKIRSRYLEDTDRNLSRDEQRAKALHIPFSVDEIVGMPVDSFNSMLSRYYLTDLQVSLIRDIRRRGKNKVAAQNCRKRKLDIILNLEDDVCNLQAKKETLKREQAQCNKAINIMKQKLHDLYHDIFSRLRDDQGRPVNPNHYALQCTHDGSILIVPKELVASGHKKETQKGKRK

Target ORF information:

RefSeq Version	NM_004289.6
Organism	Homo sapiens(human)
Definition	Homo sapiens nuclear factor, erythroid 2 like 3 (NFE2L3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004289.6

ORF Insert Sequence:

ATGAAGCACC TGAAGCGGTG GTGGTCGGCC GGCGGCGGCC TCCTGCACCT CACCCTCCTG 
CTGAGCTTGG CGGGGCTCCG CGTAGACCTA GATCTTTACC TGCTGCTGCC GCCGCCCACC 
CTGCTGCAGG ACGAGCTGCT GTTCCTGGGC GGCCCGGCCA GCTCCGCCTA CGCGCTCAGC 
CCCTTCTCGG CCTCGGGAGG GTGGGGGCGC GCGGGCCACT TGCACCCCAA GGGCCGGGAG 
CTGGACCCTG CCGCGCCGCC CGAGGGCCAG CTGCTCCGGG AGGTGCGCGC GCTCGGGGTC 
CCCTTCGTCC CTCGCACCAG CGTGGATGCA TGGCTGGTGC ACAGCGTGGC TGCCGGGAGC 
GCGGACGAGG CCCACGGGCT GCTCGGCGCC GCCGCCGCCT CGTCCACCGG AGGAGCCGGC 
GCCAGCGTGG ACGGCGGCAG CCAGGCTGTG CAGGGGGGCG GCGGGGACCC CCGAGCGGCT 
CGGAGTGGCC CCTTGGACGC CGGGGAAGAG GAGAAGGCAC CCGCGGAACC GACGGCTCAG 
GTGCCGGACG CTGGCGGATG TGCGAGCGAG GAGAATGGGG TACTAAGAGA AAAGCACGAA 
GCTGTGGATC ATAGTTCCCA GCATGAGGAA AATGAAGAAA GGGTGTCAGC CCAGAAGGAG 
AACTCACTTC AGCAGAATGA TGATGATGAA AACAAAATAG CAGAGAAACC TGACTGGGAG 
GCAGAAAAGA CCACTGAATC TAGAAATGAG AGACATCTGA ATGGGACAGA TACTTCTTTC 
TCTCTGGAAG ACTTATTCCA GTTGCTTTCA TCACAGCCTG AAAATTCACT GGAGGGCATC 
TCATTGGGAG ATATTCCTCT TCCAGGCAGT ATCAGTGATG GCATGAATTC TTCAGCACAT 
TATCATGTAA ACTTCAGCCA GGCTATAAGT CAGGATGTGA ATCTTCATGA GGCCATCTTG 
CTTTGTCCCA ACAATACATT TAGAAGAGAT CCAACAGCAA GGACTTCACA GTCACAAGAA 
CCATTTCTGC AGTTAAATTC TCATACCACC AATCCTGAGC AAACCCTTCC TGGAACTAAT 
TTGACAGGAT TTCTTTCACC GGTTGACAAT CATATGAGGA ATCTAACAAG CCAAGACCTA 
CTGTATGACC TTGACATAAA TATATTTGAT GAGATAAACT TAATGTCATT GGCCACAGAA 
GACAACTTTG ATCCAATCGA TGTTTCTCAG CTTTTTGATG AACCAGATTC TGATTCTGGC 
CTTTCTTTAG ATTCAAGTCA CAATAATACC TCTGTCATCA AGTCTAATTC CTCTCACTCT 
GTGTGTGATG AAGGTGCTAT AGGTTATTGC ACTGACCATG AATCTAGTTC CCATCATGAC 
TTAGAAGGTG CTGTAGGTGG CTACTACCCA GAACCCAGTA AGCTTTGTCA CTTGGATCAA 
AGTGATTCTG ATTTCCATGG AGATCTTACA TTTCAACACG TATTTCATAA CCACACTTAC 
CACTTACAGC CAACTGCACC AGAATCTACT TCTGAACCTT TTCCGTGGCC TGGGAAGTCA 
CAGAAGATAA GGAGTAGATA CCTTGAAGAC ACAGATAGAA ACTTGAGCCG TGATGAACAG 
CGTGCTAAAG CTTTGCATAT CCCTTTTTCT GTAGATGAAA TTGTCGGCAT GCCTGTTGAT 
TCTTTCAATA GCATGTTAAG TAGATATTAT CTGACAGACC TACAAGTCTC ACTTATCCGT 
GACATCAGAC GAAGAGGGAA AAATAAAGTT GCTGCGCAGA ACTGTCGTAA ACGCAAATTG 
GACATAATTT TGAATTTAGA AGATGATGTA TGTAACTTGC AAGCAAAGAA GGAAACTCTT 
AAGAGAGAGC AAGCACAATG TAACAAAGCT ATTAACATAA TGAAACAGAA ACTGCATGAC 
CTTTATCATG ATATTTTTAG TAGATTAAGA GATGACCAAG GTAGGCCAGT CAATCCCAAC 
CACTATGCTC TCCAGTGTAC CCATGATGGA AGTATCTTGA TAGTACCCAA AGAACTGGTG 
GCCTCAGGCC ACAAAAAGGA AACCCAAAAG GGAAAGAGAA AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Multiple regulatory mechanisms of the biological function of NRF3 (NFE2L3) control cancer cell proliferation.
Scientific reports7(1)12494(2017 Oct)
Chowdhury AMMA,Katoh H,Hatanaka A,Iwanari H,Nakamura N,Hamakubo T,Natsume T,Waku T,Kobayashi A

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NFE2L3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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