ADAM23 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ADAM23
Entrez Gene ID	8745
Full Name	ADAM metallopeptidase domain 23
Synonyms	MDC-3,MDC3
General protein information	Preferred Names ADAM metallopeptidase domain 23 Names disintegrin and metalloproteinase domain-containing protein 23 metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2q33.3
Summary	This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. It is reported that inactivation of this gene is associated with tumorigenesis in human cancers. [provided by RefSeq, May 2013].
Disorder MIM:	603710

mRNA and Protein(s)

mRNA	Protein	Name
XM_011512086.2	XP_011510388.1	disintegrin and metalloproteinase domain-containing protein 23 isoform X2
NM_003812.4	NP_003803.1	disintegrin and metalloproteinase domain-containing protein 23 preproprotein
NM_003812.3	NP_003803.1	disintegrin and metalloproteinase domain-containing protein 23 preproprotein
XM_005246932.3	XP_005246989.1	disintegrin and metalloproteinase domain-containing protein 23 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	ADAM23	NP_003803.1
	ADAM23	XP_001106619.2
Bos taurus (cattle)	ADAM23	NP_001076927.1
Rattus norvegicus (Norway rat)	Adam23	NP_001025070.1
Gallus gallus (chicken)	ADAM23	NP_001138702.1
Pan troglodytes (chimpanzee)	ADAM23	XP_516049.3
Mus musculus (house mouse)	Adam23	NP_035910.1
Canis lupus familiaris (dog)	ADAM23	XP_849852.1
Xenopus tropicalis (tropical clawed frog)	adam23	NP_001233135.1
Danio rerio (zebrafish)	wu:fj40f01	XP_005165908.1

Gene Ontology
Bibliography

Related articles in PubMed

ADAM23 promotes neuronal differentiation of human neural progenitor cells.
Markus-Koch A, Schmitt O, Seemann S, Lukas J, Koczan D, Ernst M, Fuellen G, Wree A, Rolfs A, Luo J
Cellular & molecular biology letters2216(2017)

Secretion-Positive LGI1 Mutations Linked to Lateral Temporal Epilepsy Impair Binding to ADAM22 and ADAM23 Receptors.
Dazzo E, Leonardi E, Belluzzi E, Malacrida S, Vitiello L, Greggio E, Tosatto SC, Nobile C
PLoS genetics12(10)e1006376(2016 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

ADAM23 regulates neuronal differentiation by triggering specific signaling pathways during human neural progenitor cells differentiation.
Title: ADAM23 promotes neuronal differentiation of human neural progenitor cells.

these results support the existence of a second mechanism, alternative to inhibition of protein secretion, by which ADLTE-causing LGI1 mutations exert their loss-of-function effect extracellularly, and suggest that interactions of LGI1 with both ADAM22 and ADAM23 play an important role in the molecular mechanisms leading to utosomal dominant lateral temporal epilepsy
Title: Secretion-Positive LGI1 Mutations Linked to Lateral Temporal Epilepsy Impair Binding to ADAM22 and ADAM23 Receptors.

Our data provide evidence that ADAM23 plays a role in suppression of cancer cell progression through interaction with aVb3 integrin, and suggest that downregulation of ADAM23 in SP cells may contribute toward providing a cancer stem cell phenotype
Title: ADAM23 is downregulated in side population and suppresses lung metastasis of lung carcinoma cells.

quantification of CXCL12 and ADAM23 methylation could be useful for the prediction of advanced stage of BC
Title: CXCL12 and ADAM23 hypermethylation are associated with advanced breast cancers.

High ADAM23 gene methylation is associated with gastric tumor aggressiveness.
Title: Epigenetic clustering of gastric carcinomas based on DNA methylation profiles at the precancerous stage: its correlation with tumor aggressiveness and patient outcome.

The following ADAM23 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ADAM23 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu23052	NM_003812.4 Latest version!	Homo sapiens ADAM metallopeptidase domain 23 (ADAM23), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$265.30 $379.00
OHu36717	XM_005246932.3 Latest version!	Homo sapiens ADAM metallopeptidase domain 23 (ADAM23), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
OHu62161	XM_011512086.2 Latest version!	Homo sapiens ADAM metallopeptidase domain 23 (ADAM23), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
View Old Accession Versions >>
OHu23052	NM_003812.3	Homo sapiens ADAM metallopeptidase domain 23 (ADAM23), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$265.30 $379.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ADAM23 ( NM_003812.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_003803.1 Homo sapiens ADAM metallopeptidase domain 23 (ADAM23), mRNA.

Price & Availability↑

CloneID	OHu23052
Clone ID Related Accession (Same CDS sequence)	NM_003812.4 , NM_003812.3
Accession Version	NM_003812.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2499bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	disintegrin and metalloproteinase domain-containing protein 23 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC009225.4, CN399765.1, AB009672.1, AC010731.3 and R43984.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_003812.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.226371.1, AJ005580.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142680 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000264377.8/ ENSP00000264377.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAGCCGC CCGGCAGCAG CTCGCGGCAG CCGCCCCTGG CGGGCTGCAG CCTTGCCGGC 
GCTTCCTGCG GCCCCCAACG CGGCCCCGCC GGCTCGGTGC CTGCCAGCGC CCCGGCCCGC 
ACGCCGCCCT GCCGCCTGCT TCTCGTCCTT CTCCTGCTGC CTCCGCTCGC CGCCTCGTCC 
CGGCCCCGCG CCTGGGGGGC TGCTGCGCCC AGCGCTCCGC ATTGGAATGA AACTGCAGAA 
AAAAATTTGG GAGTCCTGGC AGATGAAGAC AATACATTGC AACAGAATAG CAGCAGTAAT 
ATCAGTTACA GCAATGCAAT GCAGAAAGAA ATCACACTGC CTTCAAGACT CATATATTAC 
ATCAACCAAG ACTCGGAAAG CCCTTATCAC GTTCTTGACA CAAAGGCAAG ACACCAGCAA 
AAACATAATA AGGCTGTCCA TCTGGCCCAG GCAAGCTTCC AGATTGAAGC CTTCGGCTCC 
AAATTCATTC TTGACCTCAT ACTGAACAAT GGTTTGTTGT CTTCTGATTA TGTGGAGATT 
CACTACGAAA ATGGGAAACC ACAGTACTCT AAGGGTGGAG AGCACTGTTA CTACCATGGA 
AGCATCAGAG GCGTCAAAGA CTCCAAGGTG GCTCTGTCAA CCTGCAATGG ACTTCATGGC 
ATGTTTGAAG ATGATACCTT CGTGTATATG ATAGAGCCAC TAGAGCTGGT TCATGATGAG 
AAAAGCACAG GTCGACCACA TATAATCCAG AAAACCTTGG CAGGACAGTA TTCTAAGCAA 
ATGAAGAATC TCACTATGGA AAGAGGTGAC CAGTGGCCCT TTCTCTCTGA ATTACAGTGG 
TTGAAAAGAA GGAAGAGAGC AGTGAATCCA TCACGTGGTA TATTTGAAGA AATGAAATAT 
TTGGAACTTA TGATTGTTAA TGATCACAAA ACGTATAAGA AGCATCGCTC TTCTCATGCA 
CATACCAACA ACTTTGCAAA GTCCGTGGTC AACCTTGTGG ATTCTATTTA CAAGGAGCAG 
CTCAACACCA GGGTTGTCCT GGTGGCTGTA GAGACCTGGA CTGAGAAGGA TCAGATTGAC 
ATCACCACCA ACCCTGTGCA GATGCTCCAT GAGTTCTCAA AATACCGGCA GCGCATTAAG 
CAGCATGCTG ATGCTGTGCA CCTCATCTCG CGGGTGACAT TTCACTATAA GAGAAGCAGT 
CTGAGTTACT TTGGAGGTGT CTGTTCTCGC ACAAGAGGAG TTGGTGTGAA TGAGTATGGT 
CTTCCAATGG CAGTGGCACA AGTATTATCG CAGAGCCTGG CTCAAAACCT TGGAATCCAA 
TGGGAACCTT CTAGCAGAAA GCCAAAATGT GACTGCACAG AATCCTGGGG TGGCTGCATC 
ATGGAGGAAA CAGGGGTGTC CCATTCTCGA AAATTTTCAA AGTGCAGCAT TTTGGAGTAT 
AGAGACTTTT TACAGAGAGG AGGTGGAGCC TGCCTTTTCA ACAGGCCAAC AAAGCTATTT 
GAGCCCACGG AATGTGGAAA TGGATACGTG GAAGCTGGGG AGGAGTGTGA TTGTGGTTTT 
CATGTGGAAT GCTATGGATT ATGCTGTAAG AAATGTTCCC TCTCCAACGG GGCTCACTGC 
AGCGACGGGC CCTGCTGTAA CAATACCTCA TGTCTTTTTC AGCCACGAGG GTATGAATGC 
CGGGATGCTG TGAACGAGTG TGATATTACT GAATATTGTA CTGGAGACTC TGGTCAGTGC 
CCACCAAATC TTCATAAGCA AGACGGATAT GCATGCAATC AAAATCAGGG CCGCTGCTAC 
AATGGCGAGT GCAAGACCAG AGACAACCAG TGTCAGTACA TCTGGGGAAC AAAGGCTGCA 
GGGTCTGACA AGTTCTGCTA TGAAAAGCTG AATACAGAAG GCACTGAGAA GGGAAACTGC 
GGGAAGGATG GAGACCGGTG GATTCAGTGC AGCAAACATG ATGTGTTCTG TGGATTCTTA 
CTCTGTACCA ATCTTACTCG AGCTCCACGT ATTGGTCAAC TTCAGGGTGA GATCATTCCA 
ACTTCCTTCT ACCATCAAGG CCGGGTGATT GACTGCAGTG GTGCCCATGT AGTTTTAGAT 
GATGATACGG ATGTGGGCTA TGTAGAAGAT GGAACGCCAT GTGGCCCGTC TATGATGTGT 
TTAGATCGGA AGTGCCTACA AATTCAAGCC CTAAATATGA GCAGCTGTCC ACTCGATTCC 
AAGGGTAAAG TCTGTTCGGG CCATGGGGTG TGTAGTAATG AAGCCACCTG CATTTGTGAT 
TTCACCTGGG CAGGGACAGA TTGCAGTATC CGGGATCCAG TTAGGAACCT TCACCCCCCC 
AAGGATGAAG GACCCAAGGG TCCTAGTGCC ACCAATCTCA TAATAGGCTC CATCGCTGGT 
GCCATCCTGG TAGCAGCTAT TGTCCTTGGG GGCACAGGCT GGGGATTTAA AAATGTCAAG 
AAGAGAAGGT TCGATCCTAC TCAGCAAGGC CCCATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003803.1
CDS	336..2834
Translation	MKPPGSSSRQPPLAGCSLAGASCGPQRGPAGSVPASAPARTPPCRLLLVLLLLPPLAASSRPRAWGAAAPSAPHWNETAEKNLGVLADEDNTLQQNSSSNISYSNAMQKEITLPSRLIYYINQDSESPYHVLDTKARHQQKHNKAVHLAQASFQIEAFGSKFILDLILNNGLLSSDYVEIHYENGKPQYSKGGEHCYYHGSIRGVKDSKVALSTCNGLHGMFEDDTFVYMIEPLELVHDEKSTGRPHIIQKTLAGQYSKQMKNLTMERGDQWPFLSELQWLKRRKRAVNPSRGIFEEMKYLELMIVNDHKTYKKHRSSHAHTNNFAKSVVNLVDSIYKEQLNTRVVLVAVETWTEKDQIDITTNPVQMLHEFSKYRQRIKQHADAVHLISRVTFHYKRSSLSYFGGVCSRTRGVGVNEYGLPMAVAQVLSQSLAQNLGIQWEPSSRKPKCDCTESWGGCIMEETGVSHSRKFSKCSILEYRDFLQRGGGACLFNRPTKLFEPTECGNGYVEAGEECDCGFHVECYGLCCKKCSLSNGAHCSDGPCCNNTSCLFQPRGYECRDAVNECDITEYCTGDSGQCPPNLHKQDGYACNQNQGRCYNGECKTRDNQCQYIWGTKAAGSDKFCYEKLNTEGTEKGNCGKDGDRWIQCSKHDVFCGFLLCTNLTRAPRIGQLQGEIIPTSFYHQGRVIDCSGAHVVLDDDTDVGYVEDGTPCGPSMMCLDRKCLQIQALNMSSCPLDSKGKVCSGHGVCSNEATCICDFTWAGTDCSIRDPVRNLHPPKDEGPKGPSATNLIIGSIAGAILVAAIVLGGTGWGFKNVKKRRFDPTQQGPI

Target ORF information:

RefSeq Version	NM_003812.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase domain 23 (ADAM23), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003812.4

ORF Insert Sequence:

ATGAAGCCGC CCGGCAGCAG CTCGCGGCAG CCGCCCCTGG CGGGCTGCAG CCTTGCCGGC 
GCTTCCTGCG GCCCCCAACG CGGCCCCGCC GGCTCGGTGC CTGCCAGCGC CCCGGCCCGC 
ACGCCGCCCT GCCGCCTGCT TCTCGTCCTT CTCCTGCTGC CTCCGCTCGC CGCCTCGTCC 
CGGCCCCGCG CCTGGGGGGC TGCTGCGCCC AGCGCTCCGC ATTGGAATGA AACTGCAGAA 
AAAAATTTGG GAGTCCTGGC AGATGAAGAC AATACATTGC AACAGAATAG CAGCAGTAAT 
ATCAGTTACA GCAATGCAAT GCAGAAAGAA ATCACACTGC CTTCAAGACT CATATATTAC 
ATCAACCAAG ACTCGGAAAG CCCTTATCAC GTTCTTGACA CAAAGGCAAG ACACCAGCAA 
AAACATAATA AGGCTGTCCA TCTGGCCCAG GCAAGCTTCC AGATTGAAGC CTTCGGCTCC 
AAATTCATTC TTGACCTCAT ACTGAACAAT GGTTTGTTGT CTTCTGATTA TGTGGAGATT 
CACTACGAAA ATGGGAAACC ACAGTACTCT AAGGGTGGAG AGCACTGTTA CTACCATGGA 
AGCATCAGAG GCGTCAAAGA CTCCAAGGTG GCTCTGTCAA CCTGCAATGG ACTTCATGGC 
ATGTTTGAAG ATGATACCTT CGTGTATATG ATAGAGCCAC TAGAGCTGGT TCATGATGAG 
AAAAGCACAG GTCGACCACA TATAATCCAG AAAACCTTGG CAGGACAGTA TTCTAAGCAA 
ATGAAGAATC TCACTATGGA AAGAGGTGAC CAGTGGCCCT TTCTCTCTGA ATTACAGTGG 
TTGAAAAGAA GGAAGAGAGC AGTGAATCCA TCACGTGGTA TATTTGAAGA AATGAAATAT 
TTGGAACTTA TGATTGTTAA TGATCACAAA ACGTATAAGA AGCATCGCTC TTCTCATGCA 
CATACCAACA ACTTTGCAAA GTCCGTGGTC AACCTTGTGG ATTCTATTTA CAAGGAGCAG 
CTCAACACCA GGGTTGTCCT GGTGGCTGTA GAGACCTGGA CTGAGAAGGA TCAGATTGAC 
ATCACCACCA ACCCTGTGCA GATGCTCCAT GAGTTCTCAA AATACCGGCA GCGCATTAAG 
CAGCATGCTG ATGCTGTGCA CCTCATCTCG CGGGTGACAT TTCACTATAA GAGAAGCAGT 
CTGAGTTACT TTGGAGGTGT CTGTTCTCGC ACAAGAGGAG TTGGTGTGAA TGAGTATGGT 
CTTCCAATGG CAGTGGCACA AGTATTATCG CAGAGCCTGG CTCAAAACCT TGGAATCCAA 
TGGGAACCTT CTAGCAGAAA GCCAAAATGT GACTGCACAG AATCCTGGGG TGGCTGCATC 
ATGGAGGAAA CAGGGGTGTC CCATTCTCGA AAATTTTCAA AGTGCAGCAT TTTGGAGTAT 
AGAGACTTTT TACAGAGAGG AGGTGGAGCC TGCCTTTTCA ACAGGCCAAC AAAGCTATTT 
GAGCCCACGG AATGTGGAAA TGGATACGTG GAAGCTGGGG AGGAGTGTGA TTGTGGTTTT 
CATGTGGAAT GCTATGGATT ATGCTGTAAG AAATGTTCCC TCTCCAACGG GGCTCACTGC 
AGCGACGGGC CCTGCTGTAA CAATACCTCA TGTCTTTTTC AGCCACGAGG GTATGAATGC 
CGGGATGCTG TGAACGAGTG TGATATTACT GAATATTGTA CTGGAGACTC TGGTCAGTGC 
CCACCAAATC TTCATAAGCA AGACGGATAT GCATGCAATC AAAATCAGGG CCGCTGCTAC 
AATGGCGAGT GCAAGACCAG AGACAACCAG TGTCAGTACA TCTGGGGAAC AAAGGCTGCA 
GGGTCTGACA AGTTCTGCTA TGAAAAGCTG AATACAGAAG GCACTGAGAA GGGAAACTGC 
GGGAAGGATG GAGACCGGTG GATTCAGTGC AGCAAACATG ATGTGTTCTG TGGATTCTTA 
CTCTGTACCA ATCTTACTCG AGCTCCACGT ATTGGTCAAC TTCAGGGTGA GATCATTCCA 
ACTTCCTTCT ACCATCAAGG CCGGGTGATT GACTGCAGTG GTGCCCATGT AGTTTTAGAT 
GATGATACGG ATGTGGGCTA TGTAGAAGAT GGAACGCCAT GTGGCCCGTC TATGATGTGT 
TTAGATCGGA AGTGCCTACA AATTCAAGCC CTAAATATGA GCAGCTGTCC ACTCGATTCC 
AAGGGTAAAG TCTGTTCGGG CCATGGGGTG TGTAGTAATG AAGCCACCTG CATTTGTGAT 
TTCACCTGGG CAGGGACAGA TTGCAGTATC CGGGATCCAG TTAGGAACCT TCACCCCCCC 
AAGGATGAAG GACCCAAGGG TCCTAGTGCC ACCAATCTCA TAATAGGCTC CATCGCTGGT 
GCCATCCTGG TAGCAGCTAT TGTCCTTGGG GGCACAGGCT GGGGATTTAA AAATGTCAAG 
AAGAGAAGGT TCGATCCTAC TCAGCAAGGC CCCATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAM23 ( NM_003812.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_003803.1 Homo sapiens ADAM metallopeptidase domain 23 (ADAM23), mRNA.

Price & Availability↑

CloneID	OHu23052
Clone ID Related Accession (Same CDS sequence)	NM_003812.4 , NM_003812.3
Accession Version	NM_003812.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2499bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-11
Organism	Homo sapiens(human)
Product	disintegrin and metalloproteinase domain-containing protein 23 preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CN399765.1, AB009672.1, AC010731.3 and R43984.1. This sequence is a reference standard in the RefSeqGene project. On May 14, 2013 this sequence version replaced NM_003812.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB009672.1, SRR1803616.226371.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142680 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGCCGC CCGGCAGCAG CTCGCGGCAG CCGCCCCTGG CGGGCTGCAG CCTTGCCGGC 
GCTTCCTGCG GCCCCCAACG CGGCCCCGCC GGCTCGGTGC CTGCCAGCGC CCCGGCCCGC 
ACGCCGCCCT GCCGCCTGCT TCTCGTCCTT CTCCTGCTGC CTCCGCTCGC CGCCTCGTCC 
CGGCCCCGCG CCTGGGGGGC TGCTGCGCCC AGCGCTCCGC ATTGGAATGA AACTGCAGAA 
AAAAATTTGG GAGTCCTGGC AGATGAAGAC AATACATTGC AACAGAATAG CAGCAGTAAT 
ATCAGTTACA GCAATGCAAT GCAGAAAGAA ATCACACTGC CTTCAAGACT CATATATTAC 
ATCAACCAAG ACTCGGAAAG CCCTTATCAC GTTCTTGACA CAAAGGCAAG ACACCAGCAA 
AAACATAATA AGGCTGTCCA TCTGGCCCAG GCAAGCTTCC AGATTGAAGC CTTCGGCTCC 
AAATTCATTC TTGACCTCAT ACTGAACAAT GGTTTGTTGT CTTCTGATTA TGTGGAGATT 
CACTACGAAA ATGGGAAACC ACAGTACTCT AAGGGTGGAG AGCACTGTTA CTACCATGGA 
AGCATCAGAG GCGTCAAAGA CTCCAAGGTG GCTCTGTCAA CCTGCAATGG ACTTCATGGC 
ATGTTTGAAG ATGATACCTT CGTGTATATG ATAGAGCCAC TAGAGCTGGT TCATGATGAG 
AAAAGCACAG GTCGACCACA TATAATCCAG AAAACCTTGG CAGGACAGTA TTCTAAGCAA 
ATGAAGAATC TCACTATGGA AAGAGGTGAC CAGTGGCCCT TTCTCTCTGA ATTACAGTGG 
TTGAAAAGAA GGAAGAGAGC AGTGAATCCA TCACGTGGTA TATTTGAAGA AATGAAATAT 
TTGGAACTTA TGATTGTTAA TGATCACAAA ACGTATAAGA AGCATCGCTC TTCTCATGCA 
CATACCAACA ACTTTGCAAA GTCCGTGGTC AACCTTGTGG ATTCTATTTA CAAGGAGCAG 
CTCAACACCA GGGTTGTCCT GGTGGCTGTA GAGACCTGGA CTGAGAAGGA TCAGATTGAC 
ATCACCACCA ACCCTGTGCA GATGCTCCAT GAGTTCTCAA AATACCGGCA GCGCATTAAG 
CAGCATGCTG ATGCTGTGCA CCTCATCTCG CGGGTGACAT TTCACTATAA GAGAAGCAGT 
CTGAGTTACT TTGGAGGTGT CTGTTCTCGC ACAAGAGGAG TTGGTGTGAA TGAGTATGGT 
CTTCCAATGG CAGTGGCACA AGTATTATCG CAGAGCCTGG CTCAAAACCT TGGAATCCAA 
TGGGAACCTT CTAGCAGAAA GCCAAAATGT GACTGCACAG AATCCTGGGG TGGCTGCATC 
ATGGAGGAAA CAGGGGTGTC CCATTCTCGA AAATTTTCAA AGTGCAGCAT TTTGGAGTAT 
AGAGACTTTT TACAGAGAGG AGGTGGAGCC TGCCTTTTCA ACAGGCCAAC AAAGCTATTT 
GAGCCCACGG AATGTGGAAA TGGATACGTG GAAGCTGGGG AGGAGTGTGA TTGTGGTTTT 
CATGTGGAAT GCTATGGATT ATGCTGTAAG AAATGTTCCC TCTCCAACGG GGCTCACTGC 
AGCGACGGGC CCTGCTGTAA CAATACCTCA TGTCTTTTTC AGCCACGAGG GTATGAATGC 
CGGGATGCTG TGAACGAGTG TGATATTACT GAATATTGTA CTGGAGACTC TGGTCAGTGC 
CCACCAAATC TTCATAAGCA AGACGGATAT GCATGCAATC AAAATCAGGG CCGCTGCTAC 
AATGGCGAGT GCAAGACCAG AGACAACCAG TGTCAGTACA TCTGGGGAAC AAAGGCTGCA 
GGGTCTGACA AGTTCTGCTA TGAAAAGCTG AATACAGAAG GCACTGAGAA GGGAAACTGC 
GGGAAGGATG GAGACCGGTG GATTCAGTGC AGCAAACATG ATGTGTTCTG TGGATTCTTA 
CTCTGTACCA ATCTTACTCG AGCTCCACGT ATTGGTCAAC TTCAGGGTGA GATCATTCCA 
ACTTCCTTCT ACCATCAAGG CCGGGTGATT GACTGCAGTG GTGCCCATGT AGTTTTAGAT 
GATGATACGG ATGTGGGCTA TGTAGAAGAT GGAACGCCAT GTGGCCCGTC TATGATGTGT 
TTAGATCGGA AGTGCCTACA AATTCAAGCC CTAAATATGA GCAGCTGTCC ACTCGATTCC 
AAGGGTAAAG TCTGTTCGGG CCATGGGGTG TGTAGTAATG AAGCCACCTG CATTTGTGAT 
TTCACCTGGG CAGGGACAGA TTGCAGTATC CGGGATCCAG TTAGGAACCT TCACCCCCCC 
AAGGATGAAG GACCCAAGGG TCCTAGTGCC ACCAATCTCA TAATAGGCTC CATCGCTGGT 
GCCATCCTGG TAGCAGCTAT TGTCCTTGGG GGCACAGGCT GGGGATTTAA AAATGTCAAG 
AAGAGAAGGT TCGATCCTAC TCAGCAAGGC CCCATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003803.1
CDS	224..2722
Translation	MKPPGSSSRQPPLAGCSLAGASCGPQRGPAGSVPASAPARTPPCRLLLVLLLLPPLAASSRPRAWGAAAPSAPHWNETAEKNLGVLADEDNTLQQNSSSNISYSNAMQKEITLPSRLIYYINQDSESPYHVLDTKARHQQKHNKAVHLAQASFQIEAFGSKFILDLILNNGLLSSDYVEIHYENGKPQYSKGGEHCYYHGSIRGVKDSKVALSTCNGLHGMFEDDTFVYMIEPLELVHDEKSTGRPHIIQKTLAGQYSKQMKNLTMERGDQWPFLSELQWLKRRKRAVNPSRGIFEEMKYLELMIVNDHKTYKKHRSSHAHTNNFAKSVVNLVDSIYKEQLNTRVVLVAVETWTEKDQIDITTNPVQMLHEFSKYRQRIKQHADAVHLISRVTFHYKRSSLSYFGGVCSRTRGVGVNEYGLPMAVAQVLSQSLAQNLGIQWEPSSRKPKCDCTESWGGCIMEETGVSHSRKFSKCSILEYRDFLQRGGGACLFNRPTKLFEPTECGNGYVEAGEECDCGFHVECYGLCCKKCSLSNGAHCSDGPCCNNTSCLFQPRGYECRDAVNECDITEYCTGDSGQCPPNLHKQDGYACNQNQGRCYNGECKTRDNQCQYIWGTKAAGSDKFCYEKLNTEGTEKGNCGKDGDRWIQCSKHDVFCGFLLCTNLTRAPRIGQLQGEIIPTSFYHQGRVIDCSGAHVVLDDDTDVGYVEDGTPCGPSMMCLDRKCLQIQALNMSSCPLDSKGKVCSGHGVCSNEATCICDFTWAGTDCSIRDPVRNLHPPKDEGPKGPSATNLIIGSIAGAILVAAIVLGGTGWGFKNVKKRRFDPTQQGPI

Target ORF information:

RefSeq Version	NM_003812.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase domain 23 (ADAM23), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003812.3

ORF Insert Sequence:

ATGAAGCCGC CCGGCAGCAG CTCGCGGCAG CCGCCCCTGG CGGGCTGCAG CCTTGCCGGC 
GCTTCCTGCG GCCCCCAACG CGGCCCCGCC GGCTCGGTGC CTGCCAGCGC CCCGGCCCGC 
ACGCCGCCCT GCCGCCTGCT TCTCGTCCTT CTCCTGCTGC CTCCGCTCGC CGCCTCGTCC 
CGGCCCCGCG CCTGGGGGGC TGCTGCGCCC AGCGCTCCGC ATTGGAATGA AACTGCAGAA 
AAAAATTTGG GAGTCCTGGC AGATGAAGAC AATACATTGC AACAGAATAG CAGCAGTAAT 
ATCAGTTACA GCAATGCAAT GCAGAAAGAA ATCACACTGC CTTCAAGACT CATATATTAC 
ATCAACCAAG ACTCGGAAAG CCCTTATCAC GTTCTTGACA CAAAGGCAAG ACACCAGCAA 
AAACATAATA AGGCTGTCCA TCTGGCCCAG GCAAGCTTCC AGATTGAAGC CTTCGGCTCC 
AAATTCATTC TTGACCTCAT ACTGAACAAT GGTTTGTTGT CTTCTGATTA TGTGGAGATT 
CACTACGAAA ATGGGAAACC ACAGTACTCT AAGGGTGGAG AGCACTGTTA CTACCATGGA 
AGCATCAGAG GCGTCAAAGA CTCCAAGGTG GCTCTGTCAA CCTGCAATGG ACTTCATGGC 
ATGTTTGAAG ATGATACCTT CGTGTATATG ATAGAGCCAC TAGAGCTGGT TCATGATGAG 
AAAAGCACAG GTCGACCACA TATAATCCAG AAAACCTTGG CAGGACAGTA TTCTAAGCAA 
ATGAAGAATC TCACTATGGA AAGAGGTGAC CAGTGGCCCT TTCTCTCTGA ATTACAGTGG 
TTGAAAAGAA GGAAGAGAGC AGTGAATCCA TCACGTGGTA TATTTGAAGA AATGAAATAT 
TTGGAACTTA TGATTGTTAA TGATCACAAA ACGTATAAGA AGCATCGCTC TTCTCATGCA 
CATACCAACA ACTTTGCAAA GTCCGTGGTC AACCTTGTGG ATTCTATTTA CAAGGAGCAG 
CTCAACACCA GGGTTGTCCT GGTGGCTGTA GAGACCTGGA CTGAGAAGGA TCAGATTGAC 
ATCACCACCA ACCCTGTGCA GATGCTCCAT GAGTTCTCAA AATACCGGCA GCGCATTAAG 
CAGCATGCTG ATGCTGTGCA CCTCATCTCG CGGGTGACAT TTCACTATAA GAGAAGCAGT 
CTGAGTTACT TTGGAGGTGT CTGTTCTCGC ACAAGAGGAG TTGGTGTGAA TGAGTATGGT 
CTTCCAATGG CAGTGGCACA AGTATTATCG CAGAGCCTGG CTCAAAACCT TGGAATCCAA 
TGGGAACCTT CTAGCAGAAA GCCAAAATGT GACTGCACAG AATCCTGGGG TGGCTGCATC 
ATGGAGGAAA CAGGGGTGTC CCATTCTCGA AAATTTTCAA AGTGCAGCAT TTTGGAGTAT 
AGAGACTTTT TACAGAGAGG AGGTGGAGCC TGCCTTTTCA ACAGGCCAAC AAAGCTATTT 
GAGCCCACGG AATGTGGAAA TGGATACGTG GAAGCTGGGG AGGAGTGTGA TTGTGGTTTT 
CATGTGGAAT GCTATGGATT ATGCTGTAAG AAATGTTCCC TCTCCAACGG GGCTCACTGC 
AGCGACGGGC CCTGCTGTAA CAATACCTCA TGTCTTTTTC AGCCACGAGG GTATGAATGC 
CGGGATGCTG TGAACGAGTG TGATATTACT GAATATTGTA CTGGAGACTC TGGTCAGTGC 
CCACCAAATC TTCATAAGCA AGACGGATAT GCATGCAATC AAAATCAGGG CCGCTGCTAC 
AATGGCGAGT GCAAGACCAG AGACAACCAG TGTCAGTACA TCTGGGGAAC AAAGGCTGCA 
GGGTCTGACA AGTTCTGCTA TGAAAAGCTG AATACAGAAG GCACTGAGAA GGGAAACTGC 
GGGAAGGATG GAGACCGGTG GATTCAGTGC AGCAAACATG ATGTGTTCTG TGGATTCTTA 
CTCTGTACCA ATCTTACTCG AGCTCCACGT ATTGGTCAAC TTCAGGGTGA GATCATTCCA 
ACTTCCTTCT ACCATCAAGG CCGGGTGATT GACTGCAGTG GTGCCCATGT AGTTTTAGAT 
GATGATACGG ATGTGGGCTA TGTAGAAGAT GGAACGCCAT GTGGCCCGTC TATGATGTGT 
TTAGATCGGA AGTGCCTACA AATTCAAGCC CTAAATATGA GCAGCTGTCC ACTCGATTCC 
AAGGGTAAAG TCTGTTCGGG CCATGGGGTG TGTAGTAATG AAGCCACCTG CATTTGTGAT 
TTCACCTGGG CAGGGACAGA TTGCAGTATC CGGGATCCAG TTAGGAACCT TCACCCCCCC 
AAGGATGAAG GACCCAAGGG TCCTAGTGCC ACCAATCTCA TAATAGGCTC CATCGCTGGT 
GCCATCCTGG TAGCAGCTAT TGTCCTTGGG GGCACAGGCT GGGGATTTAA AAATGTCAAG 
AAGAGAAGGT TCGATCCTAC TCAGCAAGGC CCCATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAM23 ( XM_005246932.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005246989.1 Homo sapiens ADAM metallopeptidase domain 23 (ADAM23), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu36717
Clone ID Related Accession (Same CDS sequence)	XM_005246932.3
Accession Version	XM_005246932.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2499bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	disintegrin and metalloproteinase domain-containing protein 23 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005246932.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGCCGC CCGGCAGCAG CTCGCGGCAG CCGCCCCTGG CGGGCTGCAG CCTTGCCGGC 
GCTTCCTGCG GCCCCCAACG CGGCCCCGCC GGCTCGGTGC CTGCCAGCGC CCCGGCCCGC 
ACGCCGCCCT GCCGCCTGCT TCTCGTCCTT CTCCTGCTGC CTCCGCTCGC CGCCTCGTCC 
CGGCCCCGCG CCTGGGGGGC TGCTGCGCCC AGCGCTCCGC ATTGGAATGA AACTGCAGAA 
AAAAATTTGG GAGTCCTGGC AGATGAAGAC AATACATTGC AACAGAATAG CAGCAGTAAT 
ATCAGTTACA GCAATGCAAT GCAGAAAGAA ATCACACTGC CTTCAAGACT CATATATTAC 
ATCAACCAAG ACTCGGAAAG CCCTTATCAC GTTCTTGACA CAAAGGCAAG ACACCAGCAA 
AAACATAATA AGGCTGTCCA TCTGGCCCAG GCAAGCTTCC AGATTGAAGC CTTCGGCTCC 
AAATTCATTC TTGACCTCAT ACTGAACAAT GGTTTGTTGT CTTCTGATTA TGTGGAGATT 
CACTACGAAA ATGGGAAACC ACAGTACTCT AAGGGTGGAG AGCACTGTTA CTACCATGGA 
AGCATCAGAG GCGTCAAAGA CTCCAAGGTG GCTCTGTCAA CCTGCAATGG ACTTCATGGC 
ATGTTTGAAG ATGATACCTT CGTGTATATG ATAGAGCCAC TAGAGCTGGT TCATGATGAG 
AAAAGCACAG GTCGACCACA TATAATCCAG AAAACCTTGG CAGGACAGTA TTCTAAGCAA 
ATGAAGAATC TCACTATGGA AAGAGGTGAC CAGTGGCCCT TTCTCTCTGA ATTACAGTGG 
TTGAAAAGAA GGAAGAGAGC AGTGAATCCA TCACGTGGTA TATTTGAAGA AATGAAATAT 
TTGGAACTTA TGATTGTTAA TGATCACAAA ACGTATAAGA AGCATCGCTC TTCTCATGCA 
CATACCAACA ACTTTGCAAA GTCCGTGGTC AACCTTGTGG ATTCTATTTA CAAGGAGCAG 
CTCAACACCA GGGTTGTCCT GGTGGCTGTA GAGACCTGGA CTGAGAAGGA TCAGATTGAC 
ATCACCACCA ACCCTGTGCA GATGCTCCAT GAGTTCTCAA AATACCGGCA GCGCATTAAG 
CAGCATGCTG ATGCTGTGCA CCTCATCTCG CGGGTGACAT TTCACTATAA GAGAAGCAGT 
CTGAGTTACT TTGGAGGTGT CTGTTCTCGC ACAAGAGGAG TTGGTGTGAA TGAGTATGGT 
CTTCCAATGG CAGTGGCACA AGTATTATCG CAGAGCCTGG CTCAAAACCT TGGAATCCAA 
TGGGAACCTT CTAGCAGAAA GCCAAAATGT GACTGCACAG AATCCTGGGG TGGCTGCATC 
ATGGAGGAAA CAGGGGTGTC CCATTCTCGA AAATTTTCAA AGTGCAGCAT TTTGGAGTAT 
AGAGACTTTT TACAGAGAGG AGGTGGAGCC TGCCTTTTCA ACAGGCCAAC AAAGCTATTT 
GAGCCCACGG AATGTGGAAA TGGATACGTG GAAGCTGGGG AGGAGTGTGA TTGTGGTTTT 
CATGTGGAAT GCTATGGATT ATGCTGTAAG AAATGTTCCC TCTCCAACGG GGCTCACTGC 
AGCGACGGGC CCTGCTGTAA CAATACCTCA TGTCTTTTTC AGCCACGAGG GTATGAATGC 
CGGGATGCTG TGAACGAGTG TGATATTACT GAATATTGTA CTGGAGACTC TGGTCAGTGC 
CCACCAAATC TTCATAAGCA AGACGGATAT GCATGCAATC AAAATCAGGG CCGCTGCTAC 
AATGGCGAGT GCAAGACCAG AGACAACCAG TGTCAGTACA TCTGGGGAAC AAAGGCTGCA 
GGGTCTGACA AGTTCTGCTA TGAAAAGCTG AATACAGAAG GCACTGAGAA GGGAAACTGC 
GGGAAGGATG GAGACCGGTG GATTCAGTGC AGCAAACATG ATGTGTTCTG TGGATTCTTA 
CTCTGTACCA ATCTTACTCG AGCTCCACGT ATTGGTCAAC TTCAGGGTGA GATCATTCCA 
ACTTCCTTCT ACCATCAAGG CCGGGTGATT GACTGCAGTG GTGCCCATGT AGTTTTAGAT 
GATGATACGG ATGTGGGCTA TGTAGAAGAT GGAACGCCAT GTGGCCCGTC TATGATGTGT 
TTAGATCGGA AGTGCCTACA AATTCAAGCC CTAAATATGA GCAGCTGTCC ACTCGATTCC 
AAGGGTAAAG TCTGTTCGGG CCATGGGGTG TGTAGTAATG AAGCCACCTG CATTTGTGAT 
TTCACCTGGG CAGGGACAGA TTGCAGTATC CGGGATCCAG TTAGGAACCT TCACCCCCCC 
AAGGATGAAG GACCCAAGGA AATGTCAAGA AGAGAAGGTT CGATCCTACT CAGCAAGGCC 
CCATCTGAAT CAGCTGCGCT GGATGGACAC CGCCTTGCAC TGTTGGATTC TGGGTATGAC 
ATACTCGCAG CAGTGTTACT GGAACTATTA AGTTTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005246989.1
CDS	324..2822
Translation	MKPPGSSSRQPPLAGCSLAGASCGPQRGPAGSVPASAPARTPPCRLLLVLLLLPPLAASSRPRAWGAAAPSAPHWNETAEKNLGVLADEDNTLQQNSSSNISYSNAMQKEITLPSRLIYYINQDSESPYHVLDTKARHQQKHNKAVHLAQASFQIEAFGSKFILDLILNNGLLSSDYVEIHYENGKPQYSKGGEHCYYHGSIRGVKDSKVALSTCNGLHGMFEDDTFVYMIEPLELVHDEKSTGRPHIIQKTLAGQYSKQMKNLTMERGDQWPFLSELQWLKRRKRAVNPSRGIFEEMKYLELMIVNDHKTYKKHRSSHAHTNNFAKSVVNLVDSIYKEQLNTRVVLVAVETWTEKDQIDITTNPVQMLHEFSKYRQRIKQHADAVHLISRVTFHYKRSSLSYFGGVCSRTRGVGVNEYGLPMAVAQVLSQSLAQNLGIQWEPSSRKPKCDCTESWGGCIMEETGVSHSRKFSKCSILEYRDFLQRGGGACLFNRPTKLFEPTECGNGYVEAGEECDCGFHVECYGLCCKKCSLSNGAHCSDGPCCNNTSCLFQPRGYECRDAVNECDITEYCTGDSGQCPPNLHKQDGYACNQNQGRCYNGECKTRDNQCQYIWGTKAAGSDKFCYEKLNTEGTEKGNCGKDGDRWIQCSKHDVFCGFLLCTNLTRAPRIGQLQGEIIPTSFYHQGRVIDCSGAHVVLDDDTDVGYVEDGTPCGPSMMCLDRKCLQIQALNMSSCPLDSKGKVCSGHGVCSNEATCICDFTWAGTDCSIRDPVRNLHPPKDEGPKEMSRREGSILLSKAPSESAALDGHRLALLDSGYDILAAVLLELLSL

Target ORF information:

RefSeq Version	XM_005246932.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase domain 23 (ADAM23), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005246932.3

ORF Insert Sequence:

ATGAAGCCGC CCGGCAGCAG CTCGCGGCAG CCGCCCCTGG CGGGCTGCAG CCTTGCCGGC 
GCTTCCTGCG GCCCCCAACG CGGCCCCGCC GGCTCGGTGC CTGCCAGCGC CCCGGCCCGC 
ACGCCGCCCT GCCGCCTGCT TCTCGTCCTT CTCCTGCTGC CTCCGCTCGC CGCCTCGTCC 
CGGCCCCGCG CCTGGGGGGC TGCTGCGCCC AGCGCTCCGC ATTGGAATGA AACTGCAGAA 
AAAAATTTGG GAGTCCTGGC AGATGAAGAC AATACATTGC AACAGAATAG CAGCAGTAAT 
ATCAGTTACA GCAATGCAAT GCAGAAAGAA ATCACACTGC CTTCAAGACT CATATATTAC 
ATCAACCAAG ACTCGGAAAG CCCTTATCAC GTTCTTGACA CAAAGGCAAG ACACCAGCAA 
AAACATAATA AGGCTGTCCA TCTGGCCCAG GCAAGCTTCC AGATTGAAGC CTTCGGCTCC 
AAATTCATTC TTGACCTCAT ACTGAACAAT GGTTTGTTGT CTTCTGATTA TGTGGAGATT 
CACTACGAAA ATGGGAAACC ACAGTACTCT AAGGGTGGAG AGCACTGTTA CTACCATGGA 
AGCATCAGAG GCGTCAAAGA CTCCAAGGTG GCTCTGTCAA CCTGCAATGG ACTTCATGGC 
ATGTTTGAAG ATGATACCTT CGTGTATATG ATAGAGCCAC TAGAGCTGGT TCATGATGAG 
AAAAGCACAG GTCGACCACA TATAATCCAG AAAACCTTGG CAGGACAGTA TTCTAAGCAA 
ATGAAGAATC TCACTATGGA AAGAGGTGAC CAGTGGCCCT TTCTCTCTGA ATTACAGTGG 
TTGAAAAGAA GGAAGAGAGC AGTGAATCCA TCACGTGGTA TATTTGAAGA AATGAAATAT 
TTGGAACTTA TGATTGTTAA TGATCACAAA ACGTATAAGA AGCATCGCTC TTCTCATGCA 
CATACCAACA ACTTTGCAAA GTCCGTGGTC AACCTTGTGG ATTCTATTTA CAAGGAGCAG 
CTCAACACCA GGGTTGTCCT GGTGGCTGTA GAGACCTGGA CTGAGAAGGA TCAGATTGAC 
ATCACCACCA ACCCTGTGCA GATGCTCCAT GAGTTCTCAA AATACCGGCA GCGCATTAAG 
CAGCATGCTG ATGCTGTGCA CCTCATCTCG CGGGTGACAT TTCACTATAA GAGAAGCAGT 
CTGAGTTACT TTGGAGGTGT CTGTTCTCGC ACAAGAGGAG TTGGTGTGAA TGAGTATGGT 
CTTCCAATGG CAGTGGCACA AGTATTATCG CAGAGCCTGG CTCAAAACCT TGGAATCCAA 
TGGGAACCTT CTAGCAGAAA GCCAAAATGT GACTGCACAG AATCCTGGGG TGGCTGCATC 
ATGGAGGAAA CAGGGGTGTC CCATTCTCGA AAATTTTCAA AGTGCAGCAT TTTGGAGTAT 
AGAGACTTTT TACAGAGAGG AGGTGGAGCC TGCCTTTTCA ACAGGCCAAC AAAGCTATTT 
GAGCCCACGG AATGTGGAAA TGGATACGTG GAAGCTGGGG AGGAGTGTGA TTGTGGTTTT 
CATGTGGAAT GCTATGGATT ATGCTGTAAG AAATGTTCCC TCTCCAACGG GGCTCACTGC 
AGCGACGGGC CCTGCTGTAA CAATACCTCA TGTCTTTTTC AGCCACGAGG GTATGAATGC 
CGGGATGCTG TGAACGAGTG TGATATTACT GAATATTGTA CTGGAGACTC TGGTCAGTGC 
CCACCAAATC TTCATAAGCA AGACGGATAT GCATGCAATC AAAATCAGGG CCGCTGCTAC 
AATGGCGAGT GCAAGACCAG AGACAACCAG TGTCAGTACA TCTGGGGAAC AAAGGCTGCA 
GGGTCTGACA AGTTCTGCTA TGAAAAGCTG AATACAGAAG GCACTGAGAA GGGAAACTGC 
GGGAAGGATG GAGACCGGTG GATTCAGTGC AGCAAACATG ATGTGTTCTG TGGATTCTTA 
CTCTGTACCA ATCTTACTCG AGCTCCACGT ATTGGTCAAC TTCAGGGTGA GATCATTCCA 
ACTTCCTTCT ACCATCAAGG CCGGGTGATT GACTGCAGTG GTGCCCATGT AGTTTTAGAT 
GATGATACGG ATGTGGGCTA TGTAGAAGAT GGAACGCCAT GTGGCCCGTC TATGATGTGT 
TTAGATCGGA AGTGCCTACA AATTCAAGCC CTAAATATGA GCAGCTGTCC ACTCGATTCC 
AAGGGTAAAG TCTGTTCGGG CCATGGGGTG TGTAGTAATG AAGCCACCTG CATTTGTGAT 
TTCACCTGGG CAGGGACAGA TTGCAGTATC CGGGATCCAG TTAGGAACCT TCACCCCCCC 
AAGGATGAAG GACCCAAGGA AATGTCAAGA AGAGAAGGTT CGATCCTACT CAGCAAGGCC 
CCATCTGAAT CAGCTGCGCT GGATGGACAC CGCCTTGCAC TGTTGGATTC TGGGTATGAC 
ATACTCGCAG CAGTGTTACT GGAACTATTA AGTTTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ADAM23 ( XM_011512086.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011510388.1 Homo sapiens ADAM metallopeptidase domain 23 (ADAM23), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu62161
Clone ID Related Accession (Same CDS sequence)	XM_011512086.2
Accession Version	XM_011512086.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2499bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	disintegrin and metalloproteinase domain-containing protein 23 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011512086.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGCCGC CCGGCAGCAG CTCGCGGCAG CCGCCCCTGG CGGGCTGCAG CCTTGCCGGC 
GCTTCCTGCG GCCCCCAACG CGGCCCCGCC GGCTCGGTGC CTGCCAGCGC CCCGGCCCGC 
ACGCCGCCCT GCCGCCTGCT TCTCGTCCTT CTCCTGCTGC CTCCGCTCGC CGCCTCGTCC 
CGGCCCCGCG CCTGGGGGGC TGCTGCGCCC AGCGCTCCGC ATTGGAATGA AACTGCAGAA 
AAAAATTTGG GAGTCCTGGC AGATGAAGAC AATACATTGC AACAGAATAG CAGCAGTAAT 
ATCAGTTACA GCAATGCAAT GCAGAAAGAA ATCACACTGC CTTCAAGACT CATATATTAC 
ATCAACCAAG ACTCGGAAAG CCCTTATCAC GTTCTTGACA CAAAGGCAAG ACACCAGCAA 
AAACATAATA AGGCTGTCCA TCTGGCCCAG GCAAGCTTCC AGATTGAAGC CTTCGGCTCC 
AAATTCATTC TTGACCTCAT ACTGAACAAT GGTTTGTTGT CTTCTGATTA TGTGGAGATT 
CACTACGAAA ATGGGAAACC ACAGTACTCT AAGGGTGGAG AGCACTGTTA CTACCATGGA 
AGCATCAGAG GCGTCAAAGA CTCCAAGGTG GCTCTGTCAA CCTGCAATGG ACTTCATGGC 
ATGTTTGAAG ATGATACCTT CGTGTATATG ATAGAGCCAC TAGAGCTGGT TCATGATGAG 
AAAAGCACAG GTCGACCACA TATAATCCAG AAAACCTTGG CAGGACAGTA TTCTAAGCAA 
ATGAAGAATC TCACTATGGA AAGAGGTGAC CAGTGGCCCT TTCTCTCTGA ATTACAGTGG 
TTGAAAAGAA GGAAGAGAGC AGTGAATCCA TCACGTGGTA TATTTGAAGA AATGAAATAT 
TTGGAACTTA TGATTGTTAA TGATCACAAA ACGTATAAGA AGCATCGCTC TTCTCATGCA 
CATACCAACA ACTTTGCAAA GTCCGTGGTC AACCTTGTGG ATTCTATTTA CAAGGAGCAG 
CTCAACACCA GGGTTGTCCT GGTGGCTGTA GAGACCTGGA CTGAGAAGGA TCAGATTGAC 
ATCACCACCA ACCCTGTGCA GATGCTCCAT GAGTTCTCAA AATACCGGCA GCGCATTAAG 
CAGCATGCTG ATGCTGTGCA CCTCATCTCG CGGGTGACAT TTCACTATAA GAGAAGCAGT 
CTGAGTTACT TTGGAGGTGT CTGTTCTCGC ACAAGAGGAG TTGGTGTGAA TGAGTATGGT 
CTTCCAATGG CAGTGGCACA AGTATTATCG CAGAGCCTGG CTCAAAACCT TGGAATCCAA 
TGGGAACCTT CTAGCAGAAA GCCAAAATGT GACTGCACAG AATCCTGGGG TGGCTGCATC 
ATGGAGGAAA CAGGGGTGTC CCATTCTCGA AAATTTTCAA AGTGCAGCAT TTTGGAGTAT 
AGAGACTTTT TACAGAGAGG AGGTGGAGCC TGCCTTTTCA ACAGGCCAAC AAAGCTATTT 
GAGCCCACGG AATGTGGAAA TGGATACGTG GAAGCTGGGG AGGAGTGTGA TTGTGGTTTT 
CATGTGGAAT GCTATGGATT ATGCTGTAAG AAATGTTCCC TCTCCAACGG GGCTCACTGC 
AGCGACGGGC CCTGCTGTAA CAATACCTCA TGTCTTTTTC AGCCACGAGG GTATGAATGC 
CGGGATGCTG TGAACGAGTG TGATATTACT GAATATTGTA CTGGAGACTC TGGTCAGTGC 
CCACCAAATC TTCATAAGCA AGACGGATAT GCATGCAATC AAAATCAGGG CCGCTGCTAC 
AATGGCGAGT GCAAGACCAG AGACAACCAG TGTCAGTACA TCTGGGGAAC AAAGGCTGCA 
GGGTCTGACA AGTTCTGCTA TGAAAAGCTG AATACAGAAG GCACTGAGAA GGGAAACTGC 
GGGAAGGATG GAGACCGGTG GATTCAGTGC AGCAAACATG ATGTGTTCTG TGGATTCTTA 
CTCTGTACCA ATCTTACTCG AGCTCCACGT ATTGGTCAAC TTCAGGGTGA GATCATTCCA 
ACTTCCTTCT ACCATCAAGG CCGGGTGATT GACTGCAGTG GTGCCCATGT AGTTTTAGAT 
GATGATACGG ATGTGGGCTA TGTAGAAGAT GGAACGCCAT GTGGCCCGTC TATGATGTGT 
TTAGATCGGA AGTGCCTACA AATTCAAGCC CTAAATATGA GCAGCTGTCC ACTCGATTCC 
AAGGGTAAAG TCTGTTCGGG CCATGGGGTG TGTAGTAATG AAGCCACCTG CATTTGTGAT 
TTCACCTGGG CAGGGACAGA TTGCAGTATC CGGGATCCAG TTAGGAACCT TCACCCCCCC 
AAGGATGAAG GACCCAAGGT GAATATGGCC ACAAGCAGGC TAATAGGGGC CGTGGCCGGC 
ACCATTCTGG CCCTGGGGGT GATTTTTGGA GGCACAGGGT GGGGAATAGA AAATGTCAAG 
AAGAGAAGGT TCGATCCTAC TCAGCAAGGC CCCATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011510388.1
CDS	324..2822
Translation	MKPPGSSSRQPPLAGCSLAGASCGPQRGPAGSVPASAPARTPPCRLLLVLLLLPPLAASSRPRAWGAAAPSAPHWNETAEKNLGVLADEDNTLQQNSSSNISYSNAMQKEITLPSRLIYYINQDSESPYHVLDTKARHQQKHNKAVHLAQASFQIEAFGSKFILDLILNNGLLSSDYVEIHYENGKPQYSKGGEHCYYHGSIRGVKDSKVALSTCNGLHGMFEDDTFVYMIEPLELVHDEKSTGRPHIIQKTLAGQYSKQMKNLTMERGDQWPFLSELQWLKRRKRAVNPSRGIFEEMKYLELMIVNDHKTYKKHRSSHAHTNNFAKSVVNLVDSIYKEQLNTRVVLVAVETWTEKDQIDITTNPVQMLHEFSKYRQRIKQHADAVHLISRVTFHYKRSSLSYFGGVCSRTRGVGVNEYGLPMAVAQVLSQSLAQNLGIQWEPSSRKPKCDCTESWGGCIMEETGVSHSRKFSKCSILEYRDFLQRGGGACLFNRPTKLFEPTECGNGYVEAGEECDCGFHVECYGLCCKKCSLSNGAHCSDGPCCNNTSCLFQPRGYECRDAVNECDITEYCTGDSGQCPPNLHKQDGYACNQNQGRCYNGECKTRDNQCQYIWGTKAAGSDKFCYEKLNTEGTEKGNCGKDGDRWIQCSKHDVFCGFLLCTNLTRAPRIGQLQGEIIPTSFYHQGRVIDCSGAHVVLDDDTDVGYVEDGTPCGPSMMCLDRKCLQIQALNMSSCPLDSKGKVCSGHGVCSNEATCICDFTWAGTDCSIRDPVRNLHPPKDEGPKVNMATSRLIGAVAGTILALGVIFGGTGWGIENVKKRRFDPTQQGPI

Target ORF information:

RefSeq Version	XM_011512086.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ADAM metallopeptidase domain 23 (ADAM23), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011512086.2

ORF Insert Sequence:

ATGAAGCCGC CCGGCAGCAG CTCGCGGCAG CCGCCCCTGG CGGGCTGCAG CCTTGCCGGC 
GCTTCCTGCG GCCCCCAACG CGGCCCCGCC GGCTCGGTGC CTGCCAGCGC CCCGGCCCGC 
ACGCCGCCCT GCCGCCTGCT TCTCGTCCTT CTCCTGCTGC CTCCGCTCGC CGCCTCGTCC 
CGGCCCCGCG CCTGGGGGGC TGCTGCGCCC AGCGCTCCGC ATTGGAATGA AACTGCAGAA 
AAAAATTTGG GAGTCCTGGC AGATGAAGAC AATACATTGC AACAGAATAG CAGCAGTAAT 
ATCAGTTACA GCAATGCAAT GCAGAAAGAA ATCACACTGC CTTCAAGACT CATATATTAC 
ATCAACCAAG ACTCGGAAAG CCCTTATCAC GTTCTTGACA CAAAGGCAAG ACACCAGCAA 
AAACATAATA AGGCTGTCCA TCTGGCCCAG GCAAGCTTCC AGATTGAAGC CTTCGGCTCC 
AAATTCATTC TTGACCTCAT ACTGAACAAT GGTTTGTTGT CTTCTGATTA TGTGGAGATT 
CACTACGAAA ATGGGAAACC ACAGTACTCT AAGGGTGGAG AGCACTGTTA CTACCATGGA 
AGCATCAGAG GCGTCAAAGA CTCCAAGGTG GCTCTGTCAA CCTGCAATGG ACTTCATGGC 
ATGTTTGAAG ATGATACCTT CGTGTATATG ATAGAGCCAC TAGAGCTGGT TCATGATGAG 
AAAAGCACAG GTCGACCACA TATAATCCAG AAAACCTTGG CAGGACAGTA TTCTAAGCAA 
ATGAAGAATC TCACTATGGA AAGAGGTGAC CAGTGGCCCT TTCTCTCTGA ATTACAGTGG 
TTGAAAAGAA GGAAGAGAGC AGTGAATCCA TCACGTGGTA TATTTGAAGA AATGAAATAT 
TTGGAACTTA TGATTGTTAA TGATCACAAA ACGTATAAGA AGCATCGCTC TTCTCATGCA 
CATACCAACA ACTTTGCAAA GTCCGTGGTC AACCTTGTGG ATTCTATTTA CAAGGAGCAG 
CTCAACACCA GGGTTGTCCT GGTGGCTGTA GAGACCTGGA CTGAGAAGGA TCAGATTGAC 
ATCACCACCA ACCCTGTGCA GATGCTCCAT GAGTTCTCAA AATACCGGCA GCGCATTAAG 
CAGCATGCTG ATGCTGTGCA CCTCATCTCG CGGGTGACAT TTCACTATAA GAGAAGCAGT 
CTGAGTTACT TTGGAGGTGT CTGTTCTCGC ACAAGAGGAG TTGGTGTGAA TGAGTATGGT 
CTTCCAATGG CAGTGGCACA AGTATTATCG CAGAGCCTGG CTCAAAACCT TGGAATCCAA 
TGGGAACCTT CTAGCAGAAA GCCAAAATGT GACTGCACAG AATCCTGGGG TGGCTGCATC 
ATGGAGGAAA CAGGGGTGTC CCATTCTCGA AAATTTTCAA AGTGCAGCAT TTTGGAGTAT 
AGAGACTTTT TACAGAGAGG AGGTGGAGCC TGCCTTTTCA ACAGGCCAAC AAAGCTATTT 
GAGCCCACGG AATGTGGAAA TGGATACGTG GAAGCTGGGG AGGAGTGTGA TTGTGGTTTT 
CATGTGGAAT GCTATGGATT ATGCTGTAAG AAATGTTCCC TCTCCAACGG GGCTCACTGC 
AGCGACGGGC CCTGCTGTAA CAATACCTCA TGTCTTTTTC AGCCACGAGG GTATGAATGC 
CGGGATGCTG TGAACGAGTG TGATATTACT GAATATTGTA CTGGAGACTC TGGTCAGTGC 
CCACCAAATC TTCATAAGCA AGACGGATAT GCATGCAATC AAAATCAGGG CCGCTGCTAC 
AATGGCGAGT GCAAGACCAG AGACAACCAG TGTCAGTACA TCTGGGGAAC AAAGGCTGCA 
GGGTCTGACA AGTTCTGCTA TGAAAAGCTG AATACAGAAG GCACTGAGAA GGGAAACTGC 
GGGAAGGATG GAGACCGGTG GATTCAGTGC AGCAAACATG ATGTGTTCTG TGGATTCTTA 
CTCTGTACCA ATCTTACTCG AGCTCCACGT ATTGGTCAAC TTCAGGGTGA GATCATTCCA 
ACTTCCTTCT ACCATCAAGG CCGGGTGATT GACTGCAGTG GTGCCCATGT AGTTTTAGAT 
GATGATACGG ATGTGGGCTA TGTAGAAGAT GGAACGCCAT GTGGCCCGTC TATGATGTGT 
TTAGATCGGA AGTGCCTACA AATTCAAGCC CTAAATATGA GCAGCTGTCC ACTCGATTCC 
AAGGGTAAAG TCTGTTCGGG CCATGGGGTG TGTAGTAATG AAGCCACCTG CATTTGTGAT 
TTCACCTGGG CAGGGACAGA TTGCAGTATC CGGGATCCAG TTAGGAACCT TCACCCCCCC 
AAGGATGAAG GACCCAAGGT GAATATGGCC ACAAGCAGGC TAATAGGGGC CGTGGCCGGC 
ACCATTCTGG CCCTGGGGGT GATTTTTGGA GGCACAGGGT GGGGAATAGA AAATGTCAAG 
AAGAGAAGGT TCGATCCTAC TCAGCAAGGC CCCATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ADAM23 promotes neuronal differentiation of human neural progenitor cells.
Cellular & molecular biology letters2216(2017)
Markus-Koch A,Schmitt O,Seemann S,Lukas J,Koczan D,Ernst M,Fuellen G,Wree A,Rolfs A,Luo J

Secretion-Positive LGI1 Mutations Linked to Lateral Temporal Epilepsy Impair Binding to ADAM22 and ADAM23 Receptors.
PLoS genetics12(10)e1006376(2016 Oct)
Dazzo E,Leonardi E,Belluzzi E,Malacrida S,Vitiello L,Greggio E,Tosatto SC,Nobile C

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ADAM23 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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