NFATC2IP cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NFATC2IP
Entrez Gene ID	84901
Full Name	nuclear factor of activated T cells 2 interacting protein
Synonyms	ESC2,NIP45,RAD60
General protein information	Preferred Names nuclear factor of activated T cells 2 interacting protein Names NFATC2-interacting protein 45 kDa NF-AT-interacting protein 45 kDa NFAT-interacting protein nuclear factor of activated T-cells, cytoplasmic 2-interacting protein nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16p11.2
Disorder MIM:	614525

mRNA and Protein(s)

mRNA	Protein	Name
NM_032815.3	NP_116204.3	NFATC2-interacting protein

Pathways from BioSystems

Homologies

Bos taurus (cattle)	NFATC2IP	NP_001092353.1
Pan troglodytes (chimpanzee)	NFATC2IP	XP_001146533.1
Mus musculus (house mouse)	Nfatc2ip	NP_035030.2
Danio rerio (zebrafish)	nfatc2ip	XP_683344.3
Homo sapiens (human)	NFATC2IP	NP_116204.3
	NFATC2IP	XP_002802482.1
Canis lupus familiaris (dog)	NFATC2IP	XP_003639183.1
Rattus norvegicus (Norway rat)	Nfatc2ip	NP_001007693.1

Gene Ontology
Bibliography

Related articles in PubMed

Common genetic variants associated with cognitive performance identified using the proxy-phenotype method.
Rietveld CA, Esko T, Davies G, Pers TH, Turley P, Benyamin B, Chabris CF, Emilsson V, Johnson AD, Lee JJ, de Leeuw C, Marioni RE, Medland SE, Miller MB, Rostapshova O, van der Lee SJ, Vinkhuyzen AA, Amin N, Conley D, Derringer J, van Duijn CM, Fehrmann R, Franke L, Glaeser EL, Hansell NK, Hayward C, Iacono WG, Ibrahim-Verbaas C, Jaddoe V, Karjalainen J, Laibson D, Lichtenstein P, Liewald DC, Magnusson PK, Martin NG, McGue M, McMahon G, Pedersen NL, Pinker S, Porteous DJ, Posthuma D, Rivadeneira F, Smith BH, Starr JM, Tiemeier H, Timpson NJ, Trzaskowski M, Uitterlinden AG, Verhulst FC, Ward ME, Wright MJ, Davey Smith G, Deary IJ, Johannesson M, Plomin R, Visscher PM, Benjamin DJ, Cesarini D, Koellinger PD
Proceedings of the National Academy of Sciences of the United States of America111(38)13790-4(2014 Sep)

Gene enrichment profiles reveal T-cell development, differentiation, and lineage-specific transcription factors including ZBTB25 as a novel NF-AT repressor.
Benita Y, Cao Z, Giallourakis C, Li C, Gardet A, Xavier RJ
Blood115(26)5376-84(2010 Jul)

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
Beausoleil SA, Vill?n J, Gerber SA, Rush J, Gygi SP
Nature biotechnology24(10)1285-92(2006 Oct)

Proteins with two SUMO-like domains in chromatin-associated complexes: the RENi (Rad60-Esc2-NIP45) family.
Novatchkova M, Bachmair A, Eisenhaber B, Eisenhaber F
BMC bioinformatics622(2005 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

ZBTB25 functions as a negative regulator of nuclear factor of activated T cells (NF-AT) activation, such that RNA interference mediated knockdown resulted in enhanced activation of target genes.
Title: Gene enrichment profiles reveal T-cell development, differentiation, and lineage-specific transcription factors including ZBTB25 as a novel NF-AT repressor.

The following NFATC2IP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NFATC2IP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu29500	NM_032815.3 Latest version!	Homo sapiens nuclear factor of activated T cells 2 interacting protein (NFATC2IP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NFATC2IP ( NM_032815.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_116204.3 Homo sapiens nuclear factor of activated T cells 2 interacting protein (NFATC2IP), mRNA.

Price & Availability↑

CloneID	OHu29500
Clone ID Related Accession (Same CDS sequence)	NM_032815.3
Accession Version	NM_032815.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1260bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Homo sapiens(human)
Product	NFATC2-interacting protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF458593.1, AK074761.1, AK027545.1, AL043335.2 and BC010161.2. On or before Mar 4, 2006 this sequence version replaced XM_944125.1, XM_944127.1, XM_939369.1, NM_032815.2. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.95442.1, SRR1803613.6036.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGGCGGAGC CTGTGGGGAA GCGGGGCCGC TGGTCCGGAG GTAGCGGTGC CGGCCGAGGG 
GGTCGGGGCG GCTGGGGCGG TCGGGGCCGG CGTCCTCGGG CCCAGCGGTC TCCATCCCGG 
GGCACGCTGG ACGTAGTGTC TGTGGACTTG GTCACCGACA GCGATGAGGA AATTCTGGAG 
GTCGCCACCG CTCGCGGTGC CGCGGACGAG GTTGAGGTGG AGCCCCCGGA GCCCCCGGGG 
CCGGTCGCGT CCCGGGATAA CAGCAACAGT GACAGCGAAG GGGAGGACAG GCGGCCCGCA 
GGACCCCCGC GGGAGCCGGT CAGGCGGCGG CGGCGGCTGG TGCTGGATCC GGGGGAGGCG 
CCGCTGGTTC CGGTGTACTC GGGGAAGGTT AAAAGCAGCC TTCGCCTTAT CCCAGATGAT 
CTATCCCTCC TGAAACTCTA CCCTCCAGGG GATGAGGAAG AGGCAGAGCT GGCAGATTCG 
AGTGGTCTCT ACCATGAGGG CTCCCCATCA CCAGGCTCTC CCTGGAAGAC AAAGCTGAGG 
ACTAAGGATA AAGAAGAGAA GAAAAAGACA GAGTTTCTGG ATCTGGACAA CTCTCCTCTG 
TCCCCACCTT CACCAAGGAC CAAAAGCAGA ACGCATACTC GGGCACTCAA GAAGTTAAGT 
GAGGTGAACA AGCGCCTCCA GGATCTCCGT TCCTGTCTGA GCCCCAAGCC ACCTCAGGGT 
CAAGAGCAAC AGGGCCAAGA GGATGAAGTG GTCTTGGTGG AAGGGCCCAC CCTCCCAGAG 
ACCCCCCGAC TCTTCCCACT CAAAATCCGT TGCCGGGCTG ACCTGGTCAG ATTGCCCCTC 
AGGATGTCGG AGCCCCTGCA GAGTGTGGTG GACCACATGG CCACCCACCT TGGGGTGTCC 
CCAAGCAGGA TCCTTTTGCT TTTTGGAGAG ACAGAGCTAT CACCTACTGC CACTCCCAGG 
ACCCTAAAGC TCGGAGTGGC TGACATCATT GACTGTGTGG TACTAACAAG TTCTCCAGAG 
GCCACAGAGA CGTCCCAACA GCTCCAGCTC CGGGTGCAGG GAAAGGAGAA ACACCAGACA 
CTGGAAGTCT CACTGTCTCG AGATTCCCCT CTAAAGACCC TCATGTCCCA CTATGAGGAG 
GCCATGGGAC TGTCGGGACG GAAGCTCTCC TTCTTCTTTG ATGGGACAAA GCTTTCAGGC 
AGGGAGCTGC CAGCTGACCT GGGCATGGAA TCTGGGGACC TCATTGAGGT CTGGGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_116204.3
CDS	16..1275
Translation	MAEPVGKRGRWSGGSGAGRGGRGGWGGRGRRPRAQRSPSRGTLDVVSVDLVTDSDEEILEVATARGAADEVEVEPPEPPGPVASRDNSNSDSEGEDRRPAGPPREPVRRRRRLVLDPGEAPLVPVYSGKVKSSLRLIPDDLSLLKLYPPGDEEEAELADSSGLYHEGSPSPGSPWKTKLRTKDKEEKKKTEFLDLDNSPLSPPSPRTKSRTHTRALKKLSEVNKRLQDLRSCLSPKPPQGQEQQGQEDEVVLVEGPTLPETPRLFPLKIRCRADLVRLPLRMSEPLQSVVDHMATHLGVSPSRILLLFGETELSPTATPRTLKLGVADIIDCVVLTSSPEATETSQQLQLRVQGKEKHQTLEVSLSRDSPLKTLMSHYEEAMGLSGRKLSFFFDGTKLSGRELPADLGMESGDLIEVWG

Target ORF information:

RefSeq Version	NM_032815.3
Organism	Homo sapiens(human)
Definition	Homo sapiens nuclear factor of activated T cells 2 interacting protein (NFATC2IP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032815.3

ORF Insert Sequence:

ATGGCGGAGC CTGTGGGGAA GCGGGGCCGC TGGTCCGGAG GTAGCGGTGC CGGCCGAGGG 
GGTCGGGGCG GCTGGGGCGG TCGGGGCCGG CGTCCTCGGG CCCAGCGGTC TCCATCCCGG 
GGCACGCTGG ACGTAGTGTC TGTGGACTTG GTCACCGACA GCGATGAGGA AATTCTGGAG 
GTCGCCACCG CTCGCGGTGC CGCGGACGAG GTTGAGGTGG AGCCCCCGGA GCCCCCGGGG 
CCGGTCGCGT CCCGGGATAA CAGCAACAGT GACAGCGAAG GGGAGGACAG GCGGCCCGCA 
GGACCCCCGC GGGAGCCGGT CAGGCGGCGG CGGCGGCTGG TGCTGGATCC GGGGGAGGCG 
CCGCTGGTTC CGGTGTACTC GGGGAAGGTT AAAAGCAGCC TTCGCCTTAT CCCAGATGAT 
CTATCCCTCC TGAAACTCTA CCCTCCAGGG GATGAGGAAG AGGCAGAGCT GGCAGATTCG 
AGTGGTCTCT ACCATGAGGG CTCCCCATCA CCAGGCTCTC CCTGGAAGAC AAAGCTGAGG 
ACTAAGGATA AAGAAGAGAA GAAAAAGACA GAGTTTCTGG ATCTGGACAA CTCTCCTCTG 
TCCCCACCTT CACCAAGGAC CAAAAGCAGA ACGCATACTC GGGCACTCAA GAAGTTAAGT 
GAGGTGAACA AGCGCCTCCA GGATCTCCGT TCCTGTCTGA GCCCCAAGCC ACCTCAGGGT 
CAAGAGCAAC AGGGCCAAGA GGATGAAGTG GTCTTGGTGG AAGGGCCCAC CCTCCCAGAG 
ACCCCCCGAC TCTTCCCACT CAAAATCCGT TGCCGGGCTG ACCTGGTCAG ATTGCCCCTC 
AGGATGTCGG AGCCCCTGCA GAGTGTGGTG GACCACATGG CCACCCACCT TGGGGTGTCC 
CCAAGCAGGA TCCTTTTGCT TTTTGGAGAG ACAGAGCTAT CACCTACTGC CACTCCCAGG 
ACCCTAAAGC TCGGAGTGGC TGACATCATT GACTGTGTGG TACTAACAAG TTCTCCAGAG 
GCCACAGAGA CGTCCCAACA GCTCCAGCTC CGGGTGCAGG GAAAGGAGAA ACACCAGACA 
CTGGAAGTCT CACTGTCTCG AGATTCCCCT CTAAAGACCC TCATGTCCCA CTATGAGGAG 
GCCATGGGAC TGTCGGGACG GAAGCTCTCC TTCTTCTTTG ATGGGACAAA GCTTTCAGGC 
AGGGAGCTGC CAGCTGACCT GGGCATGGAA TCTGGGGACC TCATTGAGGT CTGGGGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Common genetic variants associated with cognitive performance identified using the proxy-phenotype method.
Proceedings of the National Academy of Sciences of the United States of America111(38)13790-4(2014 Sep)
Rietveld CA,Esko T,Davies G,Pers TH,Turley P,Benyamin B,Chabris CF,Emilsson V,Johnson AD,Lee JJ,de Leeuw C,Marioni RE,Medland SE,Miller MB,Rostapshova O,van der Lee SJ,Vinkhuyzen AA,Amin N,Conley D,Derringer J,van Duijn CM,Fehrmann R,Franke L,Glaeser EL,Hansell NK,Hayward C,Iacono WG,Ibrahim-Verbaas C,Jaddoe V,Karjalainen J,Laibson D,Lichtenstein P,Liewald DC,Magnusson PK,Martin NG,McGue M,McMahon G,Pedersen NL,Pinker S,Porteous DJ,Posthuma D,Rivadeneira F,Smith BH,Starr JM,Tiemeier H,Timpson NJ,Trzaskowski M,Uitterlinden AG,Verhulst FC,Ward ME,Wright MJ,Davey Smith G,Deary IJ,Johannesson M,Plomin R,Visscher PM,Benjamin DJ,Cesarini D,Koellinger PD

Gene enrichment profiles reveal T-cell development, differentiation, and lineage-specific transcription factors including ZBTB25 as a novel NF-AT repressor.
Blood115(26)5376-84(2010 Jul)
Benita Y,Cao Z,Giallourakis C,Li C,Gardet A,Xavier RJ

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
Nature biotechnology24(10)1285-92(2006 Oct)
Beausoleil SA,Vill?n J,Gerber SA,Rush J,Gygi SP

Proteins with two SUMO-like domains in chromatin-associated complexes: the RENi (Rad60-Esc2-NIP45) family.
BMC bioinformatics622(2005 Feb)
Novatchkova M,Bachmair A,Eisenhaber B,Eisenhaber F