SH3TC2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SH3TC2
Entrez Gene ID	79628
Full Name	SH3 domain and tetratricopeptide repeats 2
Synonyms	CMT4C,MNMN
General protein information	Preferred Names SH3 domain and tetratricopeptide repeats 2 Names SH3 domain and tetratricopeptide repeat-containing protein 2 SH3 domain and tetratricopeptide repeats-containing protein 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5q32
Summary	This gene encodes a protein with two N-terminal Src homology 3 (SH3) domains and 10 tetratricopeptide repeat (TPR) motifs, and is a member of a small gene family. The gene product has been proposed to be an adapter or docking molecule. Mutations in this gene result in autosomal recessive Charcot-Marie-Tooth disease type 4C, a childhood-onset neurodegenerative disease characterized by demyelination of motor and sensory neurons. [provided by RefSeq, Jul 2008].
Disorder MIM:	608206
Disorder Html:	Charcot-Marie-Tooth disease, type 4C, 601596 (3); Mononeuropathy of the median nerve, mild, 613353 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_024577.3	NP_078853.2	SH3 domain and tetratricopeptide repeat-containing protein 2
NM_024577.4	NP_078853.2	SH3 domain and tetratricopeptide repeat-containing protein 2

Pathways from BioSystems

Homologies

Bos taurus (cattle)	SH3TC2	XP_002689331.1
Gallus gallus (chicken)	SH3TC2	XP_424256.4
Danio rerio (zebrafish)	LOC100535152	XP_003200002.2
Xenopus tropicalis (tropical clawed frog)	sh3tc2	XP_002939154.2
Homo sapiens (human)	SH3TC2	NP_078853.2
Pan troglodytes (chimpanzee)	SH3TC2	XP_527069.2
Mus musculus (house mouse)	Sh3tc2	NP_766216.2
Canis lupus familiaris (dog)	SH3TC2	XP_005619374.1
	SH3TC2	XP_001104761.1
Rattus norvegicus (Norway rat)	Sh3tc2	XP_225887.5
Danio rerio (zebrafish)	sh3tc2	XP_005173355.1

Gene Ontology
Bibliography

Related articles in PubMed

Screening for
Zhao X, Jiang MM, Yan YZ, Liu L, Xie YZ, Li XB, Hu ZM, Zi XH, Xia K, Tang BS, Zhang RX
Chinese medical journal131(2)151-155(2018 Jan)

Charcot-Marie-Tooth Disease type 4C: Novel mutations, clinical presentations, and diagnostic challenges.
Jerath NU, Mankodi A, Crawford TO, Grunseich C, Baloui H, Nnamdi-Emeratom C, Schindler AB, Heiman-Patterson T, Chrast R, Shy ME
Muscle & nerve(2017 Oct)

Novel mutations in SH3TC2 in a young Japanese girl with Charcot-Marie-Tooth disease type 4C.
Ichikawa K, Numasawa K, Takeshita S, Hashiguchi A, Takashima H
Pediatrics international : official journal of the Japan Pediatric Society58(11)1252-1254(2016 Nov)

Screening for SH3TC2 gene mutations in a series of demyelinating recessive Charcot-Marie-Tooth disease (CMT4).
Piscosquito G, Saveri P, Magri S, Ciano C, Gandioli C, Morbin M, Bella DD, Moroni I, Taroni F, Pareyson D
Journal of the peripheral nervous system : JPNS21(3)142-9(2016 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Charcot-Marie-Tooth disease type 4C (CMT4C) is an autosomal recessive demyelinating form of CMT characterized clinically by early onset and severe spinal deformities, and is caused by mutations in SH3TC2.
Title: Novel mutations in SH3TC2 in a young Japanese girl with Charcot-Marie-Tooth disease type 4C.

A homozygous missense mutation c.1894G>A of SH3TC2 is associated with Charcot-Marie-Tooth disease type 4C.
Title: [Mutation analysis for a family affected with Charcot-Marie-Tooth disease type 4C].

DNA sequence analysis in a French-Canadian family revealed a novel combination of 2 known recessive mutations, p.R904X and p.R954X, in the SH3TC2 gene.
Title: Phenotypic variability of CMT4C in a French-Canadian kindred.

The novelty of our data is the relatively high frequency of SH3TC2 and GDAP1 mutations in demyelinating and axonal forms, respectively, of Charcot-Marie-Tooth disease
Title: Charcot-Marie-Tooth disease: frequency of genetic subtypes in a Southern Italy population.

SH3TC2 is regulated by the transcription factors CREB and SOX10, define a regulatory SNP at this disease-associated locus and reveal SH3TC2 as a candidate modifier locus of CMT disease phenotypes.
Title: Haplotype-specific modulation of a SOX10/CREB response element at the Charcot-Marie-Tooth disease type 4C locus SH3TC2.

The following SH3TC2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SH3TC2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu26006	NM_024577.4 Latest version!	Homo sapiens SH3 domain and tetratricopeptide repeats 2 (SH3TC2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$459.50-$643.30 $919.00
View Old Accession Versions >>
OHu26006	NM_024577.3	Homo sapiens SH3 domain and tetratricopeptide repeats 2 (SH3TC2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$459.50-$643.30 $919.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SH3TC2 ( NM_024577.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_078853.2 Homo sapiens SH3 domain and tetratricopeptide repeats 2 (SH3TC2), mRNA.

Price & Availability↑

CloneID	OHu26006
Clone ID Related Accession (Same CDS sequence)	NM_024577.3 , NM_024577.4
Accession Version	NM_024577.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3867bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-30
Organism	Homo sapiens(human)
Product	SH3 domain and tetratricopeptide repeat-containing protein 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA856608.1, AY341075.1, AC011364.4, AC116312.2 and AF086088.1. This sequence is a reference standard in the RefSeqGene project. On May 4, 2006 this sequence version replaced NM_024577.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY341075.1, BC113879.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03267757, SAMN03568912 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGTGGCT GCTTCTGCAT CCCCAGGGAG CGGAGTCTGA CCCGGGGCCC AGGTAAAGAA 
ACTCCTTCCA AGGATCCAAC TGTATCGAGT GAGTGTATAG CCTCATCTGA ATACAAGGAA 
AAATGTTTTC TGCCACAGAA CATTAATCCA GACCTGACAC TCTCCTTCTG TGTAAAGAGC 
CGCTCCAGGA GGTGTGTAAA TGGACCCCTA CAGGAAGCTG CTCGGAGGCG GCTCTGGGCA 
CTGGAGAATG AGGACCAGGA GGTGCGCATG CTGTTTAAGG ACCTCTCAGC AAGGTTGGTC 
AGTATCCAGT CTCAGAGGGC CCAGTTTCTC ATCACCTTCA AGACCATGGA GGAAATCTGG 
AAGTTCTCCA CCTACCTTAA TTTAGGCTAC GTATCCATGT GTCTAGAACA TCTCCTCTTT 
GACCACAAGT ACTGGCTCAA CTGCATATTG GTGGAGGATA CAGAGATCCA AGTGTCTGTA 
GATGATAAAC ACCTGGAAAC AATATACCTG GGACTCCTGA TACAGGAAGG CCACTTCTTC 
TGCAGAGCCC TGTGCTCCGT GACTCCACCA GCCGAGAAGG AAGGGGAATG CTTGACACTT 
TGCAAGAATG AGTTAATCTC AGTGAAGATG GCAGAAGCTG GCTCCGAGTT GGAAGGCGTG 
TCTTTGGTGA CAGGTCAGCG GGGCCTGGTA CTGGTGTCAG CCTTGGAGCC TCTGCCTCTC 
CCTTTCCACC AGTGGTTCCT AAAGAATTAT CCAGGAAGCT GTGGCCTTTC CAGGAAGAGG 
GATTGGACAG GCTCCTATCA GATTGGCAGA GGACGCTGTA AGGCCTTGAC GGGTTATGAG 
CCAGGAGAAA AGGATGAACT GAATTTCTAC CAGGGAGAAA GCATTGAGAT CATCGGCTTT 
GTCATACCTG GGCTTCAGTG GTTCATTGGA AAGTCGACAA GTTCAGGACA AGTGGGCTTT 
GTCCCCACCA GGAACATAGA TCCTGATTCT TATTCCCCAA TGAGCAGGAA CTCTGCCTTT 
CTCAGTGATG AGGAGAGATG CTCCCTGTTG GCCCTGGGAA GTGATAAGCA GACTGAGTGT 
TCCAGCTTCC TCCACACTCT TGCTCGCACT GACATCACAT CTGTCTACCG GCTCAGTGGG 
TTTGAATCCA TCCAGAATCC TCCAAATGAT CTGAGTGCAT CCCAGCCTGA AGGTTTCAAG 
GAGGTCAGGC CTGGCAGAGC CTGGGAGGAG CATCAGGCCG TGGGGTCCAG ACAGTCCAGC 
AGCTCTGAGG ACTCCAGCCT GGAGGAGGAG CTCCTCTCGG CCACCTCAGA CAGCTATCGC 
CTGCCGGAGC CTGATGACCT TGATGACCCG GAACTGCTCA TGGACCTAAG CACTGGTCAG 
GAGGAGGAGG CTGAGAACTT CGCCCCCATA TTGGCTTTTC TGGATCATGA GGGTTATGCT 
GACCACTTTA AGAGTCTCTA TGACTTCTCC TTCTCTTTCC TCACTTCTTC CTTTTATAGC 
TTCTCTGAGG AGGATGAGTT TGTGGCCTAC CTGGAGGCAT CAAGAAAGTG GGCCAAGAAG 
AGCCACATGA CCTGGGCCCA TGCCCGTCTC TGCTTCCTCC TGGGCCGGCT GAGCATCAGG 
AAGGTCAAAC TCTCTCAGGC CAGGGTGTAC TTCGAGGAGG CCATCCACAT TCTCAATGGA 
GCATTTGAGG ACCTATCCTT GGTGGCCACT CTGTACATCA ATTTGGCTGC CATCTACCTG 
AAACAGAGGC TGAGACATAA AGGCTCCGCC CTGTTGGAAA AGGCAGGTGC CCTGCTGGCC 
TGCCTGCCTG ACCGTGAGTC TAGTGCCAAG CATGAACTCG ACGTGGTGGC CTACGTGCTG 
CGCCAGGGGA TTGTGGTGGG CAGCAGCCCG CTGGAGGCCA GGGCCTGCTT TCTGGCCATC 
CGCTTGCTCC TGAGCCTAGG CCGGCACGAG GAGGTCCTGC CCTTTGCCGA GCGCCTGCAG 
CTCCTCTCTG GACACCCTCC TGCCTCTGAG GCTGTGGCCA GTGTTTTGAG TTTTCTGTAT 
GACAAGAAAT ATCTTCCACA CCTTGCAGTG GCCTCTGTCC AGCAACATGG TATCCAGAGT 
GCCCAAGGGA TGTCTCTTCC TATTTGGCAG GTCCACCTTG TCCTCCAGAA CACAACCAAG 
CTCCTTGGCT TTCCTTCCCC AGGCTGGGGT GAAGTTTCTG CCTTGGCCTG CCCAATGCTC 
AGACAGGCCC TGGCTGCCTG TGAGGAACTA GCAGACCGGA GCACCCAGAG GGCCCTGTGT 
CTCATCCTTT CCAAAGTGTA CCTCGAGCAC AGGTCTCCTG ACGGTGCCAT CCACTACCTG 
AGCCAGGCCT TGGTGCTAGG GCAGCTGCTG GGTGAGCAGG AATCCTTTGA GTCTTCTCTC 
TGCCTGGCAT GGGCCTATCT CTTAGCCAGC CAGGCCAAGA AGGCTTTGGA TGTGCTTGAG 
CCACTGCTAT GCTCCCTGAA GGAGACAGAG AGTCTCACTC AAAGGGGAGT CATCTATAAC 
CTCCTGGGAC TTGCACTCCA AGGTGAAGGC CGGGTGAACA GGGCAGCCAA GAGCTATCTT 
CGGGCCTTGA ACAGAGCCCA GGAGGTGGGA GATGTGCATA ACCAGGCAGT GGCTATGGCC 
AATCTTGGCC ACCTGAGCCT TAAGTCCTGG GCTCAGCATC CAGCCAGAAA CTATCTCCTG 
CAGGCTGTAC GACTCTATTG TGAACTTCAG GCCAGTAAGG AGACAGACAT GGAATTAGTA 
CAGGTGTTTC TCTGGTTGGC CCAAGTTCTG GTGTCTGGAC ACCAGCTGAC CCATGGCCTT 
CTTTGTTATG AAATGGCATT GCTGTTTGGC TTAAGGCATC GACATCTAAA GAGTCAGCTT 
CAGGCCACCA AATCCCTCTG CCATTTCTAC AGCTCTGTGT CCCCAAACCC TGAGGCATGC 
ATCACCTACC ATGAGCACTG GCTGGCCCTG GCTCAGCAAC TCAGGGACCG GGAGATGGAA 
GGGAGGCTGC TGGAGTCCCT GGGGCAGCTT TATCGGAACC TAAATACCGC CAGGTCCCTC 
AGGAGGTCAC TCACATGCAT CAAGGAGAGC CTGCGTATCT TCATTGACCT GGGGGAGACA 
GACAAGGCTG CTGAGGCCTG GCTTGGGGCG GGGCGACTCC ACTACCTCAT GCAGGAAGAC 
GAGCTGGTGG AGCTGTGCCT GCAGGCAGCC ATCCAGACAG CCCTGAAGTC AGAGGAGCCT 
TTGCTGGCTC TCAAACTTTA TGAAGAAGCA GGTGATGTGT TCTTCAATGG GACCCGCCAC 
AGGCATCATG CAGTGGAGTA CTACCGAGCT GGAGCTGTTC CTTTAGCAAG GAGGTTGAAG 
GCGGTGAGAA CTGAGCTCCG GATTTTCAAT AAGCTGACAG AGCTGCAGAT TAGCCTCGAA 
GGCTATGAGA AGGCTTTGGA ATTTGCCACC CTGGCCGCCA GGCTCAGCAC AGTCACAGGA 
GATCAGAGGC AAGAGCTGGT GGCCTTTCAC CGCCTGGCTA CAGTGTACTA CTCCCTGCAC 
ATGTATGAGA TGGCTGAGGA CTGCTACCTG AAGACCCTGT CCCTCTGTCC ACCATGGCTG 
CAGAGTCCCA AGGAGGCCCT GTACTATGCC AAGGTGTATT ATCGCCTGGG CAGACTCACC 
TTCTGCCAGC TGAAGGATGC CCATGATGCC ACTGAGTACT TCCTTCTGGC CCTGGCAGCA 
GCGGTCCTGC TGGGTGATGA GGAGCTTCAG GACACCATTA GGAGCAGGCT GGACAACATC 
TGCCAGAGCC CCCTGTGGCA CAGCAGGCCC TCCGGGTGCT CCTCAGAGAG GGCGCGGTGG 
CTGAGTGGTG GTGGCCTGGC CCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_078853.2
CDS	153..4019
Translation	MGGCFCIPRERSLTRGPGKETPSKDPTVSSECIASSEYKEKCFLPQNINPDLTLSFCVKSRSRRCVNGPLQEAARRRLWALENEDQEVRMLFKDLSARLVSIQSQRAQFLITFKTMEEIWKFSTYLNLGYVSMCLEHLLFDHKYWLNCILVEDTEIQVSVDDKHLETIYLGLLIQEGHFFCRALCSVTPPAEKEGECLTLCKNELISVKMAEAGSELEGVSLVTGQRGLVLVSALEPLPLPFHQWFLKNYPGSCGLSRKRDWTGSYQIGRGRCKALTGYEPGEKDELNFYQGESIEIIGFVIPGLQWFIGKSTSSGQVGFVPTRNIDPDSYSPMSRNSAFLSDEERCSLLALGSDKQTECSSFLHTLARTDITSVYRLSGFESIQNPPNDLSASQPEGFKEVRPGRAWEEHQAVGSRQSSSSEDSSLEEELLSATSDSYRLPEPDDLDDPELLMDLSTGQEEEAENFAPILAFLDHEGYADHFKSLYDFSFSFLTSSFYSFSEEDEFVAYLEASRKWAKKSHMTWAHARLCFLLGRLSIRKVKLSQARVYFEEAIHILNGAFEDLSLVATLYINLAAIYLKQRLRHKGSALLEKAGALLACLPDRESSAKHELDVVAYVLRQGIVVGSSPLEARACFLAIRLLLSLGRHEEVLPFAERLQLLSGHPPASEAVASVLSFLYDKKYLPHLAVASVQQHGIQSAQGMSLPIWQVHLVLQNTTKLLGFPSPGWGEVSALACPMLRQALAACEELADRSTQRALCLILSKVYLEHRSPDGAIHYLSQALVLGQLLGEQESFESSLCLAWAYLLASQAKKALDVLEPLLCSLKETESLTQRGVIYNLLGLALQGEGRVNRAAKSYLRALNRAQEVGDVHNQAVAMANLGHLSLKSWAQHPARNYLLQAVRLYCELQASKETDMELVQVFLWLAQVLVSGHQLTHGLLCYEMALLFGLRHRHLKSQLQATKSLCHFYSSVSPNPEACITYHEHWLALAQQLRDREMEGRLLESLGQLYRNLNTARSLRRSLTCIKESLRIFIDLGETDKAAEAWLGAGRLHYLMQEDELVELCLQAAIQTALKSEEPLLALKLYEEAGDVFFNGTRHRHHAVEYYRAGAVPLARRLKAVRTELRIFNKLTELQISLEGYEKALEFATLAARLSTVTGDQRQELVAFHRLATVYYSLHMYEMAEDCYLKTLSLCPPWLQSPKEALYYAKVYYRLGRLTFCQLKDAHDATEYFLLALAAAVLLGDEELQDTIRSRLDNICQSPLWHSRPSGCSSERARWLSGGGLAL

Target ORF information:

RefSeq Version	NM_024577.3
Organism	Homo sapiens(human)
Definition	Homo sapiens SH3 domain and tetratricopeptide repeats 2 (SH3TC2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024577.3

ORF Insert Sequence:

ATGGGTGGCT GCTTCTGCAT CCCCAGGGAG CGGAGTCTGA CCCGGGGCCC AGGTAAAGAA 
ACTCCTTCCA AGGATCCAAC TGTATCGAGT GAGTGTATAG CCTCATCTGA ATACAAGGAA 
AAATGTTTTC TGCCACAGAA CATTAATCCA GACCTGACAC TCTCCTTCTG TGTAAAGAGC 
CGCTCCAGGA GGTGTGTAAA TGGACCCCTA CAGGAAGCTG CTCGGAGGCG GCTCTGGGCA 
CTGGAGAATG AGGACCAGGA GGTGCGCATG CTGTTTAAGG ACCTCTCAGC AAGGTTGGTC 
AGTATCCAGT CTCAGAGGGC CCAGTTTCTC ATCACCTTCA AGACCATGGA GGAAATCTGG 
AAGTTCTCCA CCTACCTTAA TTTAGGCTAC GTATCCATGT GTCTAGAACA TCTCCTCTTT 
GACCACAAGT ACTGGCTCAA CTGCATATTG GTGGAGGATA CAGAGATCCA AGTGTCTGTA 
GATGATAAAC ACCTGGAAAC AATATACCTG GGACTCCTGA TACAGGAAGG CCACTTCTTC 
TGCAGAGCCC TGTGCTCCGT GACTCCACCA GCCGAGAAGG AAGGGGAATG CTTGACACTT 
TGCAAGAATG AGTTAATCTC AGTGAAGATG GCAGAAGCTG GCTCCGAGTT GGAAGGCGTG 
TCTTTGGTGA CAGGTCAGCG GGGCCTGGTA CTGGTGTCAG CCTTGGAGCC TCTGCCTCTC 
CCTTTCCACC AGTGGTTCCT AAAGAATTAT CCAGGAAGCT GTGGCCTTTC CAGGAAGAGG 
GATTGGACAG GCTCCTATCA GATTGGCAGA GGACGCTGTA AGGCCTTGAC GGGTTATGAG 
CCAGGAGAAA AGGATGAACT GAATTTCTAC CAGGGAGAAA GCATTGAGAT CATCGGCTTT 
GTCATACCTG GGCTTCAGTG GTTCATTGGA AAGTCGACAA GTTCAGGACA AGTGGGCTTT 
GTCCCCACCA GGAACATAGA TCCTGATTCT TATTCCCCAA TGAGCAGGAA CTCTGCCTTT 
CTCAGTGATG AGGAGAGATG CTCCCTGTTG GCCCTGGGAA GTGATAAGCA GACTGAGTGT 
TCCAGCTTCC TCCACACTCT TGCTCGCACT GACATCACAT CTGTCTACCG GCTCAGTGGG 
TTTGAATCCA TCCAGAATCC TCCAAATGAT CTGAGTGCAT CCCAGCCTGA AGGTTTCAAG 
GAGGTCAGGC CTGGCAGAGC CTGGGAGGAG CATCAGGCCG TGGGGTCCAG ACAGTCCAGC 
AGCTCTGAGG ACTCCAGCCT GGAGGAGGAG CTCCTCTCGG CCACCTCAGA CAGCTATCGC 
CTGCCGGAGC CTGATGACCT TGATGACCCG GAACTGCTCA TGGACCTAAG CACTGGTCAG 
GAGGAGGAGG CTGAGAACTT CGCCCCCATA TTGGCTTTTC TGGATCATGA GGGTTATGCT 
GACCACTTTA AGAGTCTCTA TGACTTCTCC TTCTCTTTCC TCACTTCTTC CTTTTATAGC 
TTCTCTGAGG AGGATGAGTT TGTGGCCTAC CTGGAGGCAT CAAGAAAGTG GGCCAAGAAG 
AGCCACATGA CCTGGGCCCA TGCCCGTCTC TGCTTCCTCC TGGGCCGGCT GAGCATCAGG 
AAGGTCAAAC TCTCTCAGGC CAGGGTGTAC TTCGAGGAGG CCATCCACAT TCTCAATGGA 
GCATTTGAGG ACCTATCCTT GGTGGCCACT CTGTACATCA ATTTGGCTGC CATCTACCTG 
AAACAGAGGC TGAGACATAA AGGCTCCGCC CTGTTGGAAA AGGCAGGTGC CCTGCTGGCC 
TGCCTGCCTG ACCGTGAGTC TAGTGCCAAG CATGAACTCG ACGTGGTGGC CTACGTGCTG 
CGCCAGGGGA TTGTGGTGGG CAGCAGCCCG CTGGAGGCCA GGGCCTGCTT TCTGGCCATC 
CGCTTGCTCC TGAGCCTAGG CCGGCACGAG GAGGTCCTGC CCTTTGCCGA GCGCCTGCAG 
CTCCTCTCTG GACACCCTCC TGCCTCTGAG GCTGTGGCCA GTGTTTTGAG TTTTCTGTAT 
GACAAGAAAT ATCTTCCACA CCTTGCAGTG GCCTCTGTCC AGCAACATGG TATCCAGAGT 
GCCCAAGGGA TGTCTCTTCC TATTTGGCAG GTCCACCTTG TCCTCCAGAA CACAACCAAG 
CTCCTTGGCT TTCCTTCCCC AGGCTGGGGT GAAGTTTCTG CCTTGGCCTG CCCAATGCTC 
AGACAGGCCC TGGCTGCCTG TGAGGAACTA GCAGACCGGA GCACCCAGAG GGCCCTGTGT 
CTCATCCTTT CCAAAGTGTA CCTCGAGCAC AGGTCTCCTG ACGGTGCCAT CCACTACCTG 
AGCCAGGCCT TGGTGCTAGG GCAGCTGCTG GGTGAGCAGG AATCCTTTGA GTCTTCTCTC 
TGCCTGGCAT GGGCCTATCT CTTAGCCAGC CAGGCCAAGA AGGCTTTGGA TGTGCTTGAG 
CCACTGCTAT GCTCCCTGAA GGAGACAGAG AGTCTCACTC AAAGGGGAGT CATCTATAAC 
CTCCTGGGAC TTGCACTCCA AGGTGAAGGC CGGGTGAACA GGGCAGCCAA GAGCTATCTT 
CGGGCCTTGA ACAGAGCCCA GGAGGTGGGA GATGTGCATA ACCAGGCAGT GGCTATGGCC 
AATCTTGGCC ACCTGAGCCT TAAGTCCTGG GCTCAGCATC CAGCCAGAAA CTATCTCCTG 
CAGGCTGTAC GACTCTATTG TGAACTTCAG GCCAGTAAGG AGACAGACAT GGAATTAGTA 
CAGGTGTTTC TCTGGTTGGC CCAAGTTCTG GTGTCTGGAC ACCAGCTGAC CCATGGCCTT 
CTTTGTTATG AAATGGCATT GCTGTTTGGC TTAAGGCATC GACATCTAAA GAGTCAGCTT 
CAGGCCACCA AATCCCTCTG CCATTTCTAC AGCTCTGTGT CCCCAAACCC TGAGGCATGC 
ATCACCTACC ATGAGCACTG GCTGGCCCTG GCTCAGCAAC TCAGGGACCG GGAGATGGAA 
GGGAGGCTGC TGGAGTCCCT GGGGCAGCTT TATCGGAACC TAAATACCGC CAGGTCCCTC 
AGGAGGTCAC TCACATGCAT CAAGGAGAGC CTGCGTATCT TCATTGACCT GGGGGAGACA 
GACAAGGCTG CTGAGGCCTG GCTTGGGGCG GGGCGACTCC ACTACCTCAT GCAGGAAGAC 
GAGCTGGTGG AGCTGTGCCT GCAGGCAGCC ATCCAGACAG CCCTGAAGTC AGAGGAGCCT 
TTGCTGGCTC TCAAACTTTA TGAAGAAGCA GGTGATGTGT TCTTCAATGG GACCCGCCAC 
AGGCATCATG CAGTGGAGTA CTACCGAGCT GGAGCTGTTC CTTTAGCAAG GAGGTTGAAG 
GCGGTGAGAA CTGAGCTCCG GATTTTCAAT AAGCTGACAG AGCTGCAGAT TAGCCTCGAA 
GGCTATGAGA AGGCTTTGGA ATTTGCCACC CTGGCCGCCA GGCTCAGCAC AGTCACAGGA 
GATCAGAGGC AAGAGCTGGT GGCCTTTCAC CGCCTGGCTA CAGTGTACTA CTCCCTGCAC 
ATGTATGAGA TGGCTGAGGA CTGCTACCTG AAGACCCTGT CCCTCTGTCC ACCATGGCTG 
CAGAGTCCCA AGGAGGCCCT GTACTATGCC AAGGTGTATT ATCGCCTGGG CAGACTCACC 
TTCTGCCAGC TGAAGGATGC CCATGATGCC ACTGAGTACT TCCTTCTGGC CCTGGCAGCA 
GCGGTCCTGC TGGGTGATGA GGAGCTTCAG GACACCATTA GGAGCAGGCT GGACAACATC 
TGCCAGAGCC CCCTGTGGCA CAGCAGGCCC TCCGGGTGCT CCTCAGAGAG GGCGCGGTGG 
CTGAGTGGTG GTGGCCTGGC CCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SH3TC2 ( NM_024577.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_078853.2 Homo sapiens SH3 domain and tetratricopeptide repeats 2 (SH3TC2), mRNA.

Price & Availability↑

CloneID	OHu26006
Clone ID Related Accession (Same CDS sequence)	NM_024577.3 , NM_024577.4
Accession Version	NM_024577.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3867bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	SH3 domain and tetratricopeptide repeat-containing protein 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY341075.1, AC011364.4, AC116312.2 and AF086088.1. On Aug 31, 2019 this sequence version replaced NM_024577.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: MK193740.1, AY341075.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGTGGCT GCTTCTGCAT CCCCAGGGAG CGGAGTCTGA CCCGGGGCCC AGGTAAAGAA 
ACTCCTTCCA AGGATCCAAC TGTATCGAGT GAGTGTATAG CCTCATCTGA ATACAAGGAA 
AAATGTTTTC TGCCACAGAA CATTAATCCA GACCTGACAC TCTCCTTCTG TGTAAAGAGC 
CGCTCCAGGA GGTGTGTAAA TGGACCCCTA CAGGAAGCTG CTCGGAGGCG GCTCTGGGCA 
CTGGAGAATG AGGACCAGGA GGTGCGCATG CTGTTTAAGG ACCTCTCAGC AAGGTTGGTC 
AGTATCCAGT CTCAGAGGGC CCAGTTTCTC ATCACCTTCA AGACCATGGA GGAAATCTGG 
AAGTTCTCCA CCTACCTTAA TTTAGGCTAC GTATCCATGT GTCTAGAACA TCTCCTCTTT 
GACCACAAGT ACTGGCTCAA CTGCATATTG GTGGAGGATA CAGAGATCCA AGTGTCTGTA 
GATGATAAAC ACCTGGAAAC AATATACCTG GGACTCCTGA TACAGGAAGG CCACTTCTTC 
TGCAGAGCCC TGTGCTCCGT GACTCCACCA GCCGAGAAGG AAGGGGAATG CTTGACACTT 
TGCAAGAATG AGTTAATCTC AGTGAAGATG GCAGAAGCTG GCTCCGAGTT GGAAGGCGTG 
TCTTTGGTGA CAGGTCAGCG GGGCCTGGTA CTGGTGTCAG CCTTGGAGCC TCTGCCTCTC 
CCTTTCCACC AGTGGTTCCT AAAGAATTAT CCAGGAAGCT GTGGCCTTTC CAGGAAGAGG 
GATTGGACAG GCTCCTATCA GATTGGCAGA GGACGCTGTA AGGCCTTGAC GGGTTATGAG 
CCAGGAGAAA AGGATGAACT GAATTTCTAC CAGGGAGAAA GCATTGAGAT CATCGGCTTT 
GTCATACCTG GGCTTCAGTG GTTCATTGGA AAGTCGACAA GTTCAGGACA AGTGGGCTTT 
GTCCCCACCA GGAACATAGA TCCTGATTCT TATTCCCCAA TGAGCAGGAA CTCTGCCTTT 
CTCAGTGATG AGGAGAGATG CTCCCTGTTG GCCCTGGGAA GTGATAAGCA GACTGAGTGT 
TCCAGCTTCC TCCACACTCT TGCTCGCACT GACATCACAT CTGTCTACCG GCTCAGTGGG 
TTTGAATCCA TCCAGAATCC TCCAAATGAT CTGAGTGCAT CCCAGCCTGA AGGTTTCAAG 
GAGGTCAGGC CTGGCAGAGC CTGGGAGGAG CATCAGGCCG TGGGGTCCAG ACAGTCCAGC 
AGCTCTGAGG ACTCCAGCCT GGAGGAGGAG CTCCTCTCGG CCACCTCAGA CAGCTATCGC 
CTGCCGGAGC CTGATGACCT TGATGACCCG GAACTGCTCA TGGACCTAAG CACTGGTCAG 
GAGGAGGAGG CTGAGAACTT CGCCCCCATA TTGGCTTTTC TGGATCATGA GGGTTATGCT 
GACCACTTTA AGAGTCTCTA TGACTTCTCC TTCTCTTTCC TCACTTCTTC CTTTTATAGC 
TTCTCTGAGG AGGATGAGTT TGTGGCCTAC CTGGAGGCAT CAAGAAAGTG GGCCAAGAAG 
AGCCACATGA CCTGGGCCCA TGCCCGTCTC TGCTTCCTCC TGGGCCGGCT GAGCATCAGG 
AAGGTCAAAC TCTCTCAGGC CAGGGTGTAC TTCGAGGAGG CCATCCACAT TCTCAATGGA 
GCATTTGAGG ACCTATCCTT GGTGGCCACT CTGTACATCA ATTTGGCTGC CATCTACCTG 
AAACAGAGGC TGAGACATAA AGGCTCCGCC CTGTTGGAAA AGGCAGGTGC CCTGCTGGCC 
TGCCTGCCTG ACCGTGAGTC TAGTGCCAAG CATGAACTCG ACGTGGTGGC CTACGTGCTG 
CGCCAGGGGA TTGTGGTGGG CAGCAGCCCG CTGGAGGCCA GGGCCTGCTT TCTGGCCATC 
CGCTTGCTCC TGAGCCTAGG CCGGCACGAG GAGGTCCTGC CCTTTGCCGA GCGCCTGCAG 
CTCCTCTCTG GACACCCTCC TGCCTCTGAG GCTGTGGCCA GTGTTTTGAG TTTTCTGTAT 
GACAAGAAAT ATCTTCCACA CCTTGCAGTG GCCTCTGTCC AGCAACATGG TATCCAGAGT 
GCCCAAGGGA TGTCTCTTCC TATTTGGCAG GTCCACCTTG TCCTCCAGAA CACAACCAAG 
CTCCTTGGCT TTCCTTCCCC AGGCTGGGGT GAAGTTTCTG CCTTGGCCTG CCCAATGCTC 
AGACAGGCCC TGGCTGCCTG TGAGGAACTA GCAGACCGGA GCACCCAGAG GGCCCTGTGT 
CTCATCCTTT CCAAAGTGTA CCTCGAGCAC AGGTCTCCTG ACGGTGCCAT CCACTACCTG 
AGCCAGGCCT TGGTGCTAGG GCAGCTGCTG GGTGAGCAGG AATCCTTTGA GTCTTCTCTC 
TGCCTGGCAT GGGCCTATCT CTTAGCCAGC CAGGCCAAGA AGGCTTTGGA TGTGCTTGAG 
CCACTGCTAT GCTCCCTGAA GGAGACAGAG AGTCTCACTC AAAGGGGAGT CATCTATAAC 
CTCCTGGGAC TTGCACTCCA AGGTGAAGGC CGGGTGAACA GGGCAGCCAA GAGCTATCTT 
CGGGCCTTGA ACAGAGCCCA GGAGGTGGGA GATGTGCATA ACCAGGCAGT GGCTATGGCC 
AATCTTGGCC ACCTGAGCCT TAAGTCCTGG GCTCAGCATC CAGCCAGAAA CTATCTCCTG 
CAGGCTGTAC GACTCTATTG TGAACTTCAG GCCAGTAAGG AGACAGACAT GGAATTAGTA 
CAGGTGTTTC TCTGGTTGGC CCAAGTTCTG GTGTCTGGAC ACCAGCTGAC CCATGGCCTT 
CTTTGTTATG AAATGGCATT GCTGTTTGGC TTAAGGCATC GACATCTAAA GAGTCAGCTT 
CAGGCCACCA AATCCCTCTG CCATTTCTAC AGCTCTGTGT CCCCAAACCC TGAGGCATGC 
ATCACCTACC ATGAGCACTG GCTGGCCCTG GCTCAGCAAC TCAGGGACCG GGAGATGGAA 
GGGAGGCTGC TGGAGTCCCT GGGGCAGCTT TATCGGAACC TAAATACCGC CAGGTCCCTC 
AGGAGGTCAC TCACATGCAT CAAGGAGAGC CTGCGTATCT TCATTGACCT GGGGGAGACA 
GACAAGGCTG CTGAGGCCTG GCTTGGGGCG GGGCGACTCC ACTACCTCAT GCAGGAAGAC 
GAGCTGGTGG AGCTGTGCCT GCAGGCAGCC ATCCAGACAG CCCTGAAGTC AGAGGAGCCT 
TTGCTGGCTC TCAAACTTTA TGAAGAAGCA GGTGATGTGT TCTTCAATGG GACCCGCCAC 
AGGCATCATG CAGTGGAGTA CTACCGAGCT GGAGCTGTTC CTTTAGCAAG GAGGTTGAAG 
GCGGTGAGAA CTGAGCTCCG GATTTTCAAT AAGCTGACAG AGCTGCAGAT TAGCCTCGAA 
GGCTATGAGA AGGCTTTGGA ATTTGCCACC CTGGCCGCCA GGCTCAGCAC AGTCACAGGA 
GATCAGAGGC AAGAGCTGGT GGCCTTTCAC CGCCTGGCTA CAGTGTACTA CTCCCTGCAC 
ATGTATGAGA TGGCTGAGGA CTGCTACCTG AAGACCCTGT CCCTCTGTCC ACCATGGCTG 
CAGAGTCCCA AGGAGGCCCT GTACTATGCC AAGGTGTATT ATCGCCTGGG CAGACTCACC 
TTCTGCCAGC TGAAGGATGC CCATGATGCC ACTGAGTACT TCCTTCTGGC CCTGGCAGCA 
GCGGTCCTGC TGGGTGATGA GGAGCTTCAG GACACCATTA GGAGCAGGCT GGACAACATC 
TGCCAGAGCC CCCTGTGGCA CAGCAGGCCC TCCGGGTGCT CCTCAGAGAG GGCGCGGTGG 
CTGAGTGGTG GTGGCCTGGC CCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_078853.2
CDS	41..3907
Translation	MGGCFCIPRERSLTRGPGKETPSKDPTVSSECIASSEYKEKCFLPQNINPDLTLSFCVKSRSRRCVNGPLQEAARRRLWALENEDQEVRMLFKDLSARLVSIQSQRAQFLITFKTMEEIWKFSTYLNLGYVSMCLEHLLFDHKYWLNCILVEDTEIQVSVDDKHLETIYLGLLIQEGHFFCRALCSVTPPAEKEGECLTLCKNELISVKMAEAGSELEGVSLVTGQRGLVLVSALEPLPLPFHQWFLKNYPGSCGLSRKRDWTGSYQIGRGRCKALTGYEPGEKDELNFYQGESIEIIGFVIPGLQWFIGKSTSSGQVGFVPTRNIDPDSYSPMSRNSAFLSDEERCSLLALGSDKQTECSSFLHTLARTDITSVYRLSGFESIQNPPNDLSASQPEGFKEVRPGRAWEEHQAVGSRQSSSSEDSSLEEELLSATSDSYRLPEPDDLDDPELLMDLSTGQEEEAENFAPILAFLDHEGYADHFKSLYDFSFSFLTSSFYSFSEEDEFVAYLEASRKWAKKSHMTWAHARLCFLLGRLSIRKVKLSQARVYFEEAIHILNGAFEDLSLVATLYINLAAIYLKQRLRHKGSALLEKAGALLACLPDRESSAKHELDVVAYVLRQGIVVGSSPLEARACFLAIRLLLSLGRHEEVLPFAERLQLLSGHPPASEAVASVLSFLYDKKYLPHLAVASVQQHGIQSAQGMSLPIWQVHLVLQNTTKLLGFPSPGWGEVSALACPMLRQALAACEELADRSTQRALCLILSKVYLEHRSPDGAIHYLSQALVLGQLLGEQESFESSLCLAWAYLLASQAKKALDVLEPLLCSLKETESLTQRGVIYNLLGLALQGEGRVNRAAKSYLRALNRAQEVGDVHNQAVAMANLGHLSLKSWAQHPARNYLLQAVRLYCELQASKETDMELVQVFLWLAQVLVSGHQLTHGLLCYEMALLFGLRHRHLKSQLQATKSLCHFYSSVSPNPEACITYHEHWLALAQQLRDREMEGRLLESLGQLYRNLNTARSLRRSLTCIKESLRIFIDLGETDKAAEAWLGAGRLHYLMQEDELVELCLQAAIQTALKSEEPLLALKLYEEAGDVFFNGTRHRHHAVEYYRAGAVPLARRLKAVRTELRIFNKLTELQISLEGYEKALEFATLAARLSTVTGDQRQELVAFHRLATVYYSLHMYEMAEDCYLKTLSLCPPWLQSPKEALYYAKVYYRLGRLTFCQLKDAHDATEYFLLALAAAVLLGDEELQDTIRSRLDNICQSPLWHSRPSGCSSERARWLSGGGLAL

Target ORF information:

RefSeq Version	NM_024577.4
Organism	Homo sapiens(human)
Definition	Homo sapiens SH3 domain and tetratricopeptide repeats 2 (SH3TC2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024577.4

ORF Insert Sequence:

ATGGGTGGCT GCTTCTGCAT CCCCAGGGAG CGGAGTCTGA CCCGGGGCCC AGGTAAAGAA 
ACTCCTTCCA AGGATCCAAC TGTATCGAGT GAGTGTATAG CCTCATCTGA ATACAAGGAA 
AAATGTTTTC TGCCACAGAA CATTAATCCA GACCTGACAC TCTCCTTCTG TGTAAAGAGC 
CGCTCCAGGA GGTGTGTAAA TGGACCCCTA CAGGAAGCTG CTCGGAGGCG GCTCTGGGCA 
CTGGAGAATG AGGACCAGGA GGTGCGCATG CTGTTTAAGG ACCTCTCAGC AAGGTTGGTC 
AGTATCCAGT CTCAGAGGGC CCAGTTTCTC ATCACCTTCA AGACCATGGA GGAAATCTGG 
AAGTTCTCCA CCTACCTTAA TTTAGGCTAC GTATCCATGT GTCTAGAACA TCTCCTCTTT 
GACCACAAGT ACTGGCTCAA CTGCATATTG GTGGAGGATA CAGAGATCCA AGTGTCTGTA 
GATGATAAAC ACCTGGAAAC AATATACCTG GGACTCCTGA TACAGGAAGG CCACTTCTTC 
TGCAGAGCCC TGTGCTCCGT GACTCCACCA GCCGAGAAGG AAGGGGAATG CTTGACACTT 
TGCAAGAATG AGTTAATCTC AGTGAAGATG GCAGAAGCTG GCTCCGAGTT GGAAGGCGTG 
TCTTTGGTGA CAGGTCAGCG GGGCCTGGTA CTGGTGTCAG CCTTGGAGCC TCTGCCTCTC 
CCTTTCCACC AGTGGTTCCT AAAGAATTAT CCAGGAAGCT GTGGCCTTTC CAGGAAGAGG 
GATTGGACAG GCTCCTATCA GATTGGCAGA GGACGCTGTA AGGCCTTGAC GGGTTATGAG 
CCAGGAGAAA AGGATGAACT GAATTTCTAC CAGGGAGAAA GCATTGAGAT CATCGGCTTT 
GTCATACCTG GGCTTCAGTG GTTCATTGGA AAGTCGACAA GTTCAGGACA AGTGGGCTTT 
GTCCCCACCA GGAACATAGA TCCTGATTCT TATTCCCCAA TGAGCAGGAA CTCTGCCTTT 
CTCAGTGATG AGGAGAGATG CTCCCTGTTG GCCCTGGGAA GTGATAAGCA GACTGAGTGT 
TCCAGCTTCC TCCACACTCT TGCTCGCACT GACATCACAT CTGTCTACCG GCTCAGTGGG 
TTTGAATCCA TCCAGAATCC TCCAAATGAT CTGAGTGCAT CCCAGCCTGA AGGTTTCAAG 
GAGGTCAGGC CTGGCAGAGC CTGGGAGGAG CATCAGGCCG TGGGGTCCAG ACAGTCCAGC 
AGCTCTGAGG ACTCCAGCCT GGAGGAGGAG CTCCTCTCGG CCACCTCAGA CAGCTATCGC 
CTGCCGGAGC CTGATGACCT TGATGACCCG GAACTGCTCA TGGACCTAAG CACTGGTCAG 
GAGGAGGAGG CTGAGAACTT CGCCCCCATA TTGGCTTTTC TGGATCATGA GGGTTATGCT 
GACCACTTTA AGAGTCTCTA TGACTTCTCC TTCTCTTTCC TCACTTCTTC CTTTTATAGC 
TTCTCTGAGG AGGATGAGTT TGTGGCCTAC CTGGAGGCAT CAAGAAAGTG GGCCAAGAAG 
AGCCACATGA CCTGGGCCCA TGCCCGTCTC TGCTTCCTCC TGGGCCGGCT GAGCATCAGG 
AAGGTCAAAC TCTCTCAGGC CAGGGTGTAC TTCGAGGAGG CCATCCACAT TCTCAATGGA 
GCATTTGAGG ACCTATCCTT GGTGGCCACT CTGTACATCA ATTTGGCTGC CATCTACCTG 
AAACAGAGGC TGAGACATAA AGGCTCCGCC CTGTTGGAAA AGGCAGGTGC CCTGCTGGCC 
TGCCTGCCTG ACCGTGAGTC TAGTGCCAAG CATGAACTCG ACGTGGTGGC CTACGTGCTG 
CGCCAGGGGA TTGTGGTGGG CAGCAGCCCG CTGGAGGCCA GGGCCTGCTT TCTGGCCATC 
CGCTTGCTCC TGAGCCTAGG CCGGCACGAG GAGGTCCTGC CCTTTGCCGA GCGCCTGCAG 
CTCCTCTCTG GACACCCTCC TGCCTCTGAG GCTGTGGCCA GTGTTTTGAG TTTTCTGTAT 
GACAAGAAAT ATCTTCCACA CCTTGCAGTG GCCTCTGTCC AGCAACATGG TATCCAGAGT 
GCCCAAGGGA TGTCTCTTCC TATTTGGCAG GTCCACCTTG TCCTCCAGAA CACAACCAAG 
CTCCTTGGCT TTCCTTCCCC AGGCTGGGGT GAAGTTTCTG CCTTGGCCTG CCCAATGCTC 
AGACAGGCCC TGGCTGCCTG TGAGGAACTA GCAGACCGGA GCACCCAGAG GGCCCTGTGT 
CTCATCCTTT CCAAAGTGTA CCTCGAGCAC AGGTCTCCTG ACGGTGCCAT CCACTACCTG 
AGCCAGGCCT TGGTGCTAGG GCAGCTGCTG GGTGAGCAGG AATCCTTTGA GTCTTCTCTC 
TGCCTGGCAT GGGCCTATCT CTTAGCCAGC CAGGCCAAGA AGGCTTTGGA TGTGCTTGAG 
CCACTGCTAT GCTCCCTGAA GGAGACAGAG AGTCTCACTC AAAGGGGAGT CATCTATAAC 
CTCCTGGGAC TTGCACTCCA AGGTGAAGGC CGGGTGAACA GGGCAGCCAA GAGCTATCTT 
CGGGCCTTGA ACAGAGCCCA GGAGGTGGGA GATGTGCATA ACCAGGCAGT GGCTATGGCC 
AATCTTGGCC ACCTGAGCCT TAAGTCCTGG GCTCAGCATC CAGCCAGAAA CTATCTCCTG 
CAGGCTGTAC GACTCTATTG TGAACTTCAG GCCAGTAAGG AGACAGACAT GGAATTAGTA 
CAGGTGTTTC TCTGGTTGGC CCAAGTTCTG GTGTCTGGAC ACCAGCTGAC CCATGGCCTT 
CTTTGTTATG AAATGGCATT GCTGTTTGGC TTAAGGCATC GACATCTAAA GAGTCAGCTT 
CAGGCCACCA AATCCCTCTG CCATTTCTAC AGCTCTGTGT CCCCAAACCC TGAGGCATGC 
ATCACCTACC ATGAGCACTG GCTGGCCCTG GCTCAGCAAC TCAGGGACCG GGAGATGGAA 
GGGAGGCTGC TGGAGTCCCT GGGGCAGCTT TATCGGAACC TAAATACCGC CAGGTCCCTC 
AGGAGGTCAC TCACATGCAT CAAGGAGAGC CTGCGTATCT TCATTGACCT GGGGGAGACA 
GACAAGGCTG CTGAGGCCTG GCTTGGGGCG GGGCGACTCC ACTACCTCAT GCAGGAAGAC 
GAGCTGGTGG AGCTGTGCCT GCAGGCAGCC ATCCAGACAG CCCTGAAGTC AGAGGAGCCT 
TTGCTGGCTC TCAAACTTTA TGAAGAAGCA GGTGATGTGT TCTTCAATGG GACCCGCCAC 
AGGCATCATG CAGTGGAGTA CTACCGAGCT GGAGCTGTTC CTTTAGCAAG GAGGTTGAAG 
GCGGTGAGAA CTGAGCTCCG GATTTTCAAT AAGCTGACAG AGCTGCAGAT TAGCCTCGAA 
GGCTATGAGA AGGCTTTGGA ATTTGCCACC CTGGCCGCCA GGCTCAGCAC AGTCACAGGA 
GATCAGAGGC AAGAGCTGGT GGCCTTTCAC CGCCTGGCTA CAGTGTACTA CTCCCTGCAC 
ATGTATGAGA TGGCTGAGGA CTGCTACCTG AAGACCCTGT CCCTCTGTCC ACCATGGCTG 
CAGAGTCCCA AGGAGGCCCT GTACTATGCC AAGGTGTATT ATCGCCTGGG CAGACTCACC 
TTCTGCCAGC TGAAGGATGC CCATGATGCC ACTGAGTACT TCCTTCTGGC CCTGGCAGCA 
GCGGTCCTGC TGGGTGATGA GGAGCTTCAG GACACCATTA GGAGCAGGCT GGACAACATC 
TGCCAGAGCC CCCTGTGGCA CAGCAGGCCC TCCGGGTGCT CCTCAGAGAG GGCGCGGTGG 
CTGAGTGGTG GTGGCCTGGC CCTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Screening for
Chinese medical journal131(2)151-155(2018 Jan)
Zhao X,Jiang MM,Yan YZ,Liu L,Xie YZ,Li XB,Hu ZM,Zi XH,Xia K,Tang BS,Zhang RX

Charcot-Marie-Tooth Disease type 4C: Novel mutations, clinical presentations, and diagnostic challenges.
Muscle & nerve(2017 Oct)
Jerath NU,Mankodi A,Crawford TO,Grunseich C,Baloui H,Nnamdi-Emeratom C,Schindler AB,Heiman-Patterson T,Chrast R,Shy ME

Novel mutations in SH3TC2 in a young Japanese girl with Charcot-Marie-Tooth disease type 4C.
Pediatrics international : official journal of the Japan Pediatric Society58(11)1252-1254(2016 Nov)
Ichikawa K,Numasawa K,Takeshita S,Hashiguchi A,Takashima H

Screening for SH3TC2 gene mutations in a series of demyelinating recessive Charcot-Marie-Tooth disease (CMT4).
Journal of the peripheral nervous system : JPNS21(3)142-9(2016 Sep)
Piscosquito G,Saveri P,Magri S,Ciano C,Gandioli C,Morbin M,Bella DD,Moroni I,Taroni F,Pareyson D

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SH3TC2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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