LAPTM5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	LAPTM5
Entrez Gene ID	7805
Full Name	lysosomal protein transmembrane 5
Synonyms	CLAST6
General protein information	Preferred Names lysosomal protein transmembrane 5 Names lysosomal-associated transmembrane protein 5 CD40-ligand-activated specific transcripts human retinoic acid-inducible E3 protein lysosomal associated multispanning membrane protein 5 lysosomal multispanning membrane protein 5 lysosomal-associated multitransmembrane protein 5 retinoic acid-inducible E3 protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p35.2
Summary	This gene encodes a transmembrane receptor that is associated with lysosomes. The encoded protein, also known as E3 protein, may play a role in hematopoiesis. [provided by RefSeq, Feb 2009].
Disorder MIM:	601476

mRNA and Protein(s)

mRNA	Protein	Name
NM_006762.2	NP_006753.1	lysosomal-associated transmembrane protein 5
NM_006762.3	NP_006753.1	lysosomal-associated transmembrane protein 5
XM_011542098.2	XP_011540400.1	lysosomal-associated transmembrane protein 5 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LAPTM5	XP_513264.3
Canis lupus familiaris (dog)	LAPTM5	XP_005617741.1
Gallus gallus (chicken)	LAPTM5	XP_417701.1
Bos taurus (cattle)	LAPTM5	NP_001039583.1
Rattus norvegicus (Norway rat)	Laptm5	NP_445990.2
Xenopus tropicalis (tropical clawed frog)	laptm5	NP_001182638.1
Homo sapiens (human)	LAPTM5	NP_006753.1
	LOC704041	XP_001092380.2
Mus musculus (house mouse)	Laptm5	NP_034816.1

Gene Ontology
Bibliography

Related articles in PubMed

Downregulation of LAPTM5 suppresses cell proliferation and viability inducing cell cycle arrest at G0/G1 phase of bladder cancer cells.
Chen L, Wang G, Luo Y, Wang Y, Xie C, Jiang W, Xiao Y, Qian G, Wang X
International journal of oncology50(1)263-271(2017 Jan)

Down-regulation of LAPTM5 in human cancer cells.
Nuylan M, Kawano T, Inazawa J, Inoue J
Oncotarget7(19)28320-8(2016 May)

Exome sequencing reveals recurrent germ line variants in patients with familial Waldenstr?m macroglobulinemia.
Roccaro AM, Sacco A, Shi J, Chiarini M, Perilla-Glen A, Manier S, Glavey S, Aljawai Y, Mishima Y, Kawano Y, Moschetta M, Correll M, Improgo MR, Brown JR, Imberti L, Rossi G, Castillo JJ, Treon SP, Freedman ML, Van Allen EM, Hide W, Hiller E, Rainville I, Ghobrial IM
Blood127(21)2598-606(2016 05)

Expression and Polymorphisms of Lysosome-Associated Protein Transmembrane 5 (LAPTM5) in Patients with Systemic Lupus Erythematosus in a Chinese Population.
Cai X, Qiao Y, Chen Y, Du S, Chen D, Yu S, Liu N, Jiang Y
Biochemical genetics53(7-8)200-10(2015 Aug)

Lysosomal-associated transmembrane protein 5 (LAPTM5) is a molecular partner of CD1e.
Ang?nieux C, Waharte F, Gidon A, Signorino-Gelo F, Wurtz V, Hojeij R, Proamer F, Gachet C, Van Dorsselaer A, Hanau D, Salamero J, de la Salle H
PloS one7(8)e42634(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Taken together, our results suggested that decreased LAPTM5 inhibited proliferation and viability, as well as induced G0/G1 cell cycle arrest possibly via deactivation of ERK1/2 and p38 in BCa cells
Title: Downregulation of LAPTM5 suppresses cell proliferation and viability inducing cell cycle arrest at G0/G1 phase of bladder cancer cells.

These findings suggest that the inactivation of LAPTM5 may contribute to tumorigenesis in a subset of human cancers
Title: Down-regulation of LAPTM5 in human cancer cells.

Insufficient expression of LAPTM5 may take part in the pathogenesis of systemic lupus erythematosus (SLE) and contribute to the severity of the disease, none of LAPTM5 polymorphisms contributes significantly to SLE susceptibility in a Chinese population.
Title: Expression and Polymorphisms of Lysosome-Associated Protein Transmembrane 5 (LAPTM5) in Patients with Systemic Lupus Erythematosus in a Chinese Population.

The interaction of LAPTM5 with CD1e and their colocalization in antigen processing compartments both suggest that LAPTM5 might influence the role of CD1e in the presentation of lipid antigens.
Title: Lysosomal-associated transmembrane protein 5 (LAPTM5) is a molecular partner of CD1e.

LAPTM5 is a substrate of the ITCH-mediated degradation and its protein level is negatively regulated by ITCH
Title: HECT-type ubiquitin ligase ITCH targets lysosomal-associated protein multispanning transmembrane 5 (LAPTM5) and prevents LAPTM5-mediated cell death.

The following LAPTM5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LAPTM5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu01225	NM_006762.3 Latest version!	Homo sapiens lysosomal protein transmembrane 5 (LAPTM5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$134.50-$188.30 $269.00
OHu61489	XM_011542098.2 Latest version!	Homo sapiens lysosomal protein transmembrane 5 (LAPTM5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu01225	NM_006762.2	Homo sapiens lysosomal protein transmembrane 5 (LAPTM5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$134.50-$188.30 $269.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LAPTM5 ( NM_006762.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_006753.1 Homo sapiens lysosomal protein transmembrane 5 (LAPTM5), mRNA.

Price & Availability↑

CloneID	OHu01225
Clone ID Related Accession (Same CDS sequence)	NM_006762.2 , NM_006762.3
Accession Version	NM_006762.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 789bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-17
Organism	Homo sapiens(human)
Product	lysosomal-associated transmembrane protein 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CT003824.1, BC106897.1, D42042.1, AL137857.29 and BF000809.1. On Feb 3, 2009 this sequence version replaced NM_006762.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.68490.1, SRR1163658.234566.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2153031, SAMEA2154529 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACCCCC GCTTGTCCAC TGTCCGCCAG ACCTGCTGCT GCTTCAATGT CCGCATCGCA 
ACCACCGCCC TGGCCATCTA CCATGTGATC ATGAGCGTCT TGTTGTTCAT CGAGCACTCA 
GTAGAGGTGG CCCATGGCAA GGCGTCCTGC AAGCTCTCCC AGATGGGCTA CCTCAGGATC 
GCTGACCTGA TCTCCAGCTT CCTGCTCATC ACCATGCTCT TCATCATCAG CCTGAGCCTA 
CTGATCGGCG TAGTCAAGAA CCGGGAGAAG TACCTGCTGC CCTTCCTGTC CCTGCAAATC 
ATGGACTATC TCCTGTGCCT GCTCACCCTG CTGGGCTCCT ACATTGAGCT GCCCGCCTAC 
CTCAAGTTGG CCTCCCGGAG CCGTGCTAGC TCCTCCAAGT TCCCCCTGAT GACGCTGCAG 
CTGCTGGACT TCTGCCTGAG CATCCTGACC CTCTGCAGCT CCTACATGGA AGTGCCCACC 
TATCTCAACT TCAAGTCCAT GAACCACATG AATTACCTCC CCAGCCAGGA GGATATGCCT 
CATAACCAGT TCATCAAGAT GATGATCATC TTTTCCATCG CCTTCATCAC TGTCCTTATC 
TTCAAGGTCT ACATGTTCAA GTGCGTGTGG CGGTGCTACA GATTGATCAA GTGCATGAAC 
TCGGTGGAGG AGAAGAGAAA CTCCAAGATG CTCCAGAAGG TGGTCCTGCC GTCCTACGAG 
GAAGCCCTGT CTTTGCCATC GAAGACCCCA GAGGGGGGCC CAGCACCACC CCCATACTCA 
GAGGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006753.1
CDS	92..880
Translation	MDPRLSTVRQTCCCFNVRIATTALAIYHVIMSVLLFIEHSVEVAHGKASCKLSQMGYLRIADLISSFLLITMLFIISLSLLIGVVKNREKYLLPFLSLQIMDYLLCLLTLLGSYIELPAYLKLASRSRASSSKFPLMTLQLLDFCLSILTLCSSYMEVPTYLNFKSMNHMNYLPSQEDMPHNQFIKMMIIFSIAFITVLIFKVYMFKCVWRCYRLIKCMNSVEEKRNSKMLQKVVLPSYEEALSLPSKTPEGGPAPPPYSEV

Target ORF information:

RefSeq Version	NM_006762.2
Organism	Homo sapiens(human)
Definition	Homo sapiens lysosomal protein transmembrane 5 (LAPTM5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006762.2

ORF Insert Sequence:

ATGGACCCCC GCTTGTCCAC TGTCCGCCAG ACCTGCTGCT GCTTCAATGT CCGCATCGCA 
ACCACCGCCC TGGCCATCTA CCATGTGATC ATGAGCGTCT TGTTGTTCAT CGAGCACTCA 
GTAGAGGTGG CCCATGGCAA GGCGTCCTGC AAGCTCTCCC AGATGGGCTA CCTCAGGATC 
GCTGACCTGA TCTCCAGCTT CCTGCTCATC ACCATGCTCT TCATCATCAG CCTGAGCCTA 
CTGATCGGCG TAGTCAAGAA CCGGGAGAAG TACCTGCTGC CCTTCCTGTC CCTGCAAATC 
ATGGACTATC TCCTGTGCCT GCTCACCCTG CTGGGCTCCT ACATTGAGCT GCCCGCCTAC 
CTCAAGTTGG CCTCCCGGAG CCGTGCTAGC TCCTCCAAGT TCCCCCTGAT GACGCTGCAG 
CTGCTGGACT TCTGCCTGAG CATCCTGACC CTCTGCAGCT CCTACATGGA AGTGCCCACC 
TATCTCAACT TCAAGTCCAT GAACCACATG AATTACCTCC CCAGCCAGGA GGATATGCCT 
CATAACCAGT TCATCAAGAT GATGATCATC TTTTCCATCG CCTTCATCAC TGTCCTTATC 
TTCAAGGTCT ACATGTTCAA GTGCGTGTGG CGGTGCTACA GATTGATCAA GTGCATGAAC 
TCGGTGGAGG AGAAGAGAAA CTCCAAGATG CTCCAGAAGG TGGTCCTGCC GTCCTACGAG 
GAAGCCCTGT CTTTGCCATC GAAGACCCCA GAGGGGGGCC CAGCACCACC CCCATACTCA 
GAGGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LAPTM5 ( NM_006762.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_006753.1 Homo sapiens lysosomal protein transmembrane 5 (LAPTM5), mRNA.

Price & Availability↑

CloneID	OHu01225
Clone ID Related Accession (Same CDS sequence)	NM_006762.2 , NM_006762.3
Accession Version	NM_006762.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 789bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	lysosomal-associated transmembrane protein 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC106897.1, D42042.1 and AL137857.29. On Nov 22, 2018 this sequence version replaced NM_006762.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U51240.1, SRR1163658.68490.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2153031, SAMEA2154529 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000294507.4/ ENSP00000294507.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGACCCCC GCTTGTCCAC TGTCCGCCAG ACCTGCTGCT GCTTCAATGT CCGCATCGCA 
ACCACCGCCC TGGCCATCTA CCATGTGATC ATGAGCGTCT TGTTGTTCAT CGAGCACTCA 
GTAGAGGTGG CCCATGGCAA GGCGTCCTGC AAGCTCTCCC AGATGGGCTA CCTCAGGATC 
GCTGACCTGA TCTCCAGCTT CCTGCTCATC ACCATGCTCT TCATCATCAG CCTGAGCCTA 
CTGATCGGCG TAGTCAAGAA CCGGGAGAAG TACCTGCTGC CCTTCCTGTC CCTGCAAATC 
ATGGACTATC TCCTGTGCCT GCTCACCCTG CTGGGCTCCT ACATTGAGCT GCCCGCCTAC 
CTCAAGTTGG CCTCCCGGAG CCGTGCTAGC TCCTCCAAGT TCCCCCTGAT GACGCTGCAG 
CTGCTGGACT TCTGCCTGAG CATCCTGACC CTCTGCAGCT CCTACATGGA AGTGCCCACC 
TATCTCAACT TCAAGTCCAT GAACCACATG AATTACCTCC CCAGCCAGGA GGATATGCCT 
CATAACCAGT TCATCAAGAT GATGATCATC TTTTCCATCG CCTTCATCAC TGTCCTTATC 
TTCAAGGTCT ACATGTTCAA GTGCGTGTGG CGGTGCTACA GATTGATCAA GTGCATGAAC 
TCGGTGGAGG AGAAGAGAAA CTCCAAGATG CTCCAGAAGG TGGTCCTGCC GTCCTACGAG 
GAAGCCCTGT CTTTGCCATC GAAGACCCCA GAGGGGGGCC CAGCACCACC CCCATACTCA 
GAGGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006753.1
CDS	30..818
Translation	MDPRLSTVRQTCCCFNVRIATTALAIYHVIMSVLLFIEHSVEVAHGKASCKLSQMGYLRIADLISSFLLITMLFIISLSLLIGVVKNREKYLLPFLSLQIMDYLLCLLTLLGSYIELPAYLKLASRSRASSSKFPLMTLQLLDFCLSILTLCSSYMEVPTYLNFKSMNHMNYLPSQEDMPHNQFIKMMIIFSIAFITVLIFKVYMFKCVWRCYRLIKCMNSVEEKRNSKMLQKVVLPSYEEALSLPSKTPEGGPAPPPYSEV

Target ORF information:

RefSeq Version	NM_006762.3
Organism	Homo sapiens(human)
Definition	Homo sapiens lysosomal protein transmembrane 5 (LAPTM5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006762.3

ORF Insert Sequence:

ATGGACCCCC GCTTGTCCAC TGTCCGCCAG ACCTGCTGCT GCTTCAATGT CCGCATCGCA 
ACCACCGCCC TGGCCATCTA CCATGTGATC ATGAGCGTCT TGTTGTTCAT CGAGCACTCA 
GTAGAGGTGG CCCATGGCAA GGCGTCCTGC AAGCTCTCCC AGATGGGCTA CCTCAGGATC 
GCTGACCTGA TCTCCAGCTT CCTGCTCATC ACCATGCTCT TCATCATCAG CCTGAGCCTA 
CTGATCGGCG TAGTCAAGAA CCGGGAGAAG TACCTGCTGC CCTTCCTGTC CCTGCAAATC 
ATGGACTATC TCCTGTGCCT GCTCACCCTG CTGGGCTCCT ACATTGAGCT GCCCGCCTAC 
CTCAAGTTGG CCTCCCGGAG CCGTGCTAGC TCCTCCAAGT TCCCCCTGAT GACGCTGCAG 
CTGCTGGACT TCTGCCTGAG CATCCTGACC CTCTGCAGCT CCTACATGGA AGTGCCCACC 
TATCTCAACT TCAAGTCCAT GAACCACATG AATTACCTCC CCAGCCAGGA GGATATGCCT 
CATAACCAGT TCATCAAGAT GATGATCATC TTTTCCATCG CCTTCATCAC TGTCCTTATC 
TTCAAGGTCT ACATGTTCAA GTGCGTGTGG CGGTGCTACA GATTGATCAA GTGCATGAAC 
TCGGTGGAGG AGAAGAGAAA CTCCAAGATG CTCCAGAAGG TGGTCCTGCC GTCCTACGAG 
GAAGCCCTGT CTTTGCCATC GAAGACCCCA GAGGGGGGCC CAGCACCACC CCCATACTCA 
GAGGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LAPTM5 ( XM_011542098.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011540400.1 Homo sapiens lysosomal protein transmembrane 5 (LAPTM5), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu61489
Clone ID Related Accession (Same CDS sequence)	XM_011542098.2
Accession Version	XM_011542098.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 618bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	lysosomal-associated transmembrane protein 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011542098.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACCCCC GCTTGTCCAC TGTCCGCCAG ACCTGCTGCT GCTTCAATGT CCGCATCGCA 
ACCACCGCCC TGGCCATCTA CCATGTGAAC CGGGAGAAGT ACCTGCTGCC CTTCCTGTCC 
CTGCAAATCA TGGACTATCT CCTGTGCCTG CTCACCCTGC TGGGCTCCTA CATTGAGCTG 
CCCGCCTACC TCAAGTTGGC CTCCCGGAGC CGTGCTAGCT CCTCCAAGTT CCCCCTGATG 
ACGCTGCAGC TGCTGGACTT CTGCCTGAGC ATCCTGACCC TCTGCAGCTC CTACATGGAA 
GTGCCCACCT ATCTCAACTT CAAGTCCATG AACCACATGA ATTACCTCCC CAGCCAGGAG 
GATATGCCTC ATAACCAGTT CATCAAGATG ATGATCATCT TTTCCATCGC CTTCATCACT 
GTCCTTATCT TCAAGGTCTA CATGTTCAAG TGCGTGTGGC GGTGCTACAG ATTGATCAAG 
TGCATGAACT CGGTGGAGGA GAAGAGAAAC TCCAAGATGC TCCAGAAGGT GGTCCTGCCG 
TCCTACGAGG AAGCCCTGTC TTTGCCATCG AAGACCCCAG AGGGGGGCCC AGCACCACCC 
CCATACTCAG AGGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011540400.1
CDS	96..713
Translation	MDPRLSTVRQTCCCFNVRIATTALAIYHVNREKYLLPFLSLQIMDYLLCLLTLLGSYIELPAYLKLASRSRASSSKFPLMTLQLLDFCLSILTLCSSYMEVPTYLNFKSMNHMNYLPSQEDMPHNQFIKMMIIFSIAFITVLIFKVYMFKCVWRCYRLIKCMNSVEEKRNSKMLQKVVLPSYEEALSLPSKTPEGGPAPPPYSEV

Target ORF information:

RefSeq Version	XM_011542098.2
Organism	Homo sapiens(human)
Definition	Homo sapiens lysosomal protein transmembrane 5 (LAPTM5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011542098.2

ORF Insert Sequence:

ATGGACCCCC GCTTGTCCAC TGTCCGCCAG ACCTGCTGCT GCTTCAATGT CCGCATCGCA 
ACCACCGCCC TGGCCATCTA CCATGTGAAC CGGGAGAAGT ACCTGCTGCC CTTCCTGTCC 
CTGCAAATCA TGGACTATCT CCTGTGCCTG CTCACCCTGC TGGGCTCCTA CATTGAGCTG 
CCCGCCTACC TCAAGTTGGC CTCCCGGAGC CGTGCTAGCT CCTCCAAGTT CCCCCTGATG 
ACGCTGCAGC TGCTGGACTT CTGCCTGAGC ATCCTGACCC TCTGCAGCTC CTACATGGAA 
GTGCCCACCT ATCTCAACTT CAAGTCCATG AACCACATGA ATTACCTCCC CAGCCAGGAG 
GATATGCCTC ATAACCAGTT CATCAAGATG ATGATCATCT TTTCCATCGC CTTCATCACT 
GTCCTTATCT TCAAGGTCTA CATGTTCAAG TGCGTGTGGC GGTGCTACAG ATTGATCAAG 
TGCATGAACT CGGTGGAGGA GAAGAGAAAC TCCAAGATGC TCCAGAAGGT GGTCCTGCCG 
TCCTACGAGG AAGCCCTGTC TTTGCCATCG AAGACCCCAG AGGGGGGCCC AGCACCACCC 
CCATACTCAG AGGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Downregulation of LAPTM5 suppresses cell proliferation and viability inducing cell cycle arrest at G0/G1 phase of bladder cancer cells.
International journal of oncology50(1)263-271(2017 Jan)
Chen L,Wang G,Luo Y,Wang Y,Xie C,Jiang W,Xiao Y,Qian G,Wang X

Down-regulation of LAPTM5 in human cancer cells.
Oncotarget7(19)28320-8(2016 May)
Nuylan M,Kawano T,Inazawa J,Inoue J

Exome sequencing reveals recurrent germ line variants in patients with familial Waldenstr?m macroglobulinemia.
Blood127(21)2598-606(2016 05)
Roccaro AM,Sacco A,Shi J,Chiarini M,Perilla-Glen A,Manier S,Glavey S,Aljawai Y,Mishima Y,Kawano Y,Moschetta M,Correll M,Improgo MR,Brown JR,Imberti L,Rossi G,Castillo JJ,Treon SP,Freedman ML,Van Allen EM,Hide W,Hiller E,Rainville I,Ghobrial IM

Expression and Polymorphisms of Lysosome-Associated Protein Transmembrane 5 (LAPTM5) in Patients with Systemic Lupus Erythematosus in a Chinese Population.
Biochemical genetics53(7-8)200-10(2015 Aug)
Cai X,Qiao Y,Chen Y,Du S,Chen D,Yu S,Liu N,Jiang Y

Lysosomal-associated transmembrane protein 5 (LAPTM5) is a molecular partner of CD1e.
PloS one7(8)e42634(2012)
Ang?nieux C,Waharte F,Gidon A,Signorino-Gelo F,Wurtz V,Hojeij R,Proamer F,Gachet C,Van Dorsselaer A,Hanau D,Salamero J,de la Salle H

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LAPTM5 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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Services & Products

見積依頼

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電話

FAX

オンラインフォーム