PLEKHA3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PLEKHA3
Entrez Gene ID	65977
Full Name	pleckstrin homology domain containing A3
Synonyms	FAPP1
General protein information	Preferred Names pleckstrin homology domain containing A3 Names pleckstrin homology domain-containing family A member 3 FAPP-1 PH domain-containing family A member 3 four-phosphate-adaptor protein 1 phosphatidylinositol-four-phosphate adapter protein 1 phosphoinositol 4-phosphate adapter protein 1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2q31.2
Disorder MIM:	607774

mRNA and Protein(s)

mRNA	Protein	Name
XM_011511689.3	XP_011509991.1	pleckstrin homology domain-containing family A member 3 isoform X1
XM_011511689.2	XP_011509991.1	pleckstrin homology domain-containing family A member 3 isoform X1
NM_019091.4	NP_061964.3	pleckstrin homology domain-containing family A member 3
NM_019091.3	NP_061964.3	pleckstrin homology domain-containing family A member 3

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	PLEKHA3	XP_545547.4
Xenopus tropicalis (tropical clawed frog)	plekha3	NP_001120200.1
Pan troglodytes (chimpanzee)	PLEKHA3	XP_515943.2
	PLEKHA3	XP_001099197.1
Bos taurus (cattle)	PLEKHA3	NP_001095383.1
Mus musculus (house mouse)	Plekha3	NP_112546.1
Gallus gallus (chicken)	PLEKHA3	NP_001026422.1
Rattus norvegicus (Norway rat)	Plekha3	NP_001013095.1
Danio rerio (zebrafish)	plekha3	NP_957501.1
Homo sapiens (human)	PLEKHA3	NP_061964.3

Gene Ontology
Bibliography

Related articles in PubMed

Interaction of Fapp1 with Arf1 and PI4P at a membrane surface: an example of coincidence detection.
Liu Y, Kahn RA, Prestegard JH
Structure (London, England : 1993)22(3)421-30(2014 Mar)

Secondary structure and 1H, 13C, 15N resonance assignments of the Golgi-specific PH domain of FAPP1.
Lenoir M, Whittaker SB, Overduin M
Biomolecular NMR assignments5(2)185-7(2011 Oct)

Molecular basis of phosphatidylinositol 4-phosphate and ARF1 GTPase recognition by the FAPP1 pleckstrin homology (PH) domain.
He J, Scott JL, Heroux A, Roy S, Lenoir M, Overduin M, Stahelin RV, Kutateladze TG
The Journal of biological chemistry286(21)18650-7(2011 May)

Structural basis of wedging the Golgi membrane by FAPP pleckstrin homology domains.
Lenoir M, Coskun U, Grzybek M, Cao X, Buschhorn SB, James J, Simons K, Overduin M
EMBO reports11(4)279-84(2010 Apr)

Transcriptome analysis of human gastric cancer.
Oh JH, Yang JO, Hahn Y, Kim MR, Byun SS, Jeon YJ, Kim JM, Song KS, Noh SM, Kim S, Yoo HS, Kim YS, Kim NS
Mammalian genome : official journal of the International Mammalian Genome Society16(12)942-54(2005 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Binding sites on Fapp1 protein for Arf1 and phosphatidylinositol-4-phosphate minimally overlap
Title: Interaction of Fapp1 with Arf1 and PI4P at a membrane surface: an example of coincidence detection.

We report the complete (1)H, (13)C and (15)N resonance assignments of the FAPP1-PH in its free state and those induced by PtdIns(4)P or detergent micelles.
Title: Secondary structure and 1H, 13C, 15N resonance assignments of the Golgi-specific PH domain of FAPP1.

Molecular basis of phosphatidylinositol 4-phosphate and ARF1 GTPase recognition by the FAPP1 pleckstrin homology (PH) domain.
Title: Molecular basis of phosphatidylinositol 4-phosphate and ARF1 GTPase recognition by the FAPP1 pleckstrin homology (PH) domain.

The micelle-bound structure of the FAPP1 pleckstrin homology domain reveals how its prominent wedge independently tubulates Golgi membranes by leaflet penetration.
Title: Structural basis of wedging the Golgi membrane by FAPP pleckstrin homology domains.

Data show that FAPP1 and 2 are essential components of a phosphatidylinositol 4-phosphate- and ADP-ribosylation factor-regulated machinery that controls generation of constitutive post-Golgi carriers.
Title: FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)P.

The following PLEKHA3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PLEKHA3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29448	NM_019091.4 Latest version!	Homo sapiens pleckstrin homology domain containing A3 (PLEKHA3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu36562	XM_011511689.3 Latest version!	Homo sapiens pleckstrin homology domain containing A3 (PLEKHA3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
View Old Accession Versions >>
OHu36562	XM_011511689.2	Homo sapiens pleckstrin homology domain containing A3 (PLEKHA3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OHu29448	NM_019091.3	Homo sapiens pleckstrin homology domain containing A3 (PLEKHA3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PLEKHA3 ( NM_019091.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_061964.3 Homo sapiens pleckstrin homology domain containing A3 (PLEKHA3), mRNA.

Price & Availability↑

CloneID	OHu29448
Clone ID Related Accession (Same CDS sequence)	NM_019091.4 , NM_019091.3
Accession Version	NM_019091.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 903bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-07
Organism	Homo sapiens(human)
Product	pleckstrin homology domain-containing family A member 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC009948.3, BM794932.1, AK074209.1 and BC039812.1. On Nov 23, 2018 this sequence version replaced NM_019091.3. ##Evidence-Data-START## Transcript exon combination :: AF286162.1, SRR1660807.218785.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000234453.10/ ENSP00000234453.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGGGGG TGTTGTACAA GTGGACCAAC TATCTCACAG GCTGGCAGCC TCGTTGGTTT 
GTTTTAGATA ATGGAATCTT ATCCTACTAT GATTCACAAG ATGATGTTTG CAAAGGGAGC 
AAAGGAAGCA TAAAGATGGC AGTTTGTGAA ATTAAAGTTC ATTCAGCAGA CAACACAAGA 
ATGGAATTAA TCATTCCTGG AGAGCAGCAT TTCTACATGA AGGCAGTGAA TGCAGCTGAA 
AGACAGAGGT GGCTGGTCGC TCTGGGGAGC TCCAAAGCAT GTTTGACTGA TACAAGGACT 
AAAAAAGAAA AAGAAATAAG TGAAACCAGT GAATCGCTGA AAACCAAAAT GTCTGAACTT 
CGCCTCTACT GTGACCTCTT AATGCAGCAA GTTCATACAA TACAGGAATT TGTTCACCAT 
GATGAGAATC ATTCATCTCC TAGTGCAGAG AACATGAATG AAGCCTCTTC TCTGCTTAGT 
GCCACGTGTA ACACATTCAT CACAACGCTT GAGGAATGTG TGAAGATAGC CAATGCCAAG 
TTTAAACCTG AGATGTTTCA ACTGCACCAT CCGGATCCCT TAGTTTCTCC TGTGTCACCT 
TCTCCTGTTC AAATGATGAA GCGTTCTGTC AGCCACCCTG GTTCTTGCAG TTCAGAGAGG 
AGTAGCCACT CTATAAAAGA ACCAGTATCT ACACTTCACC GACTCTCCCA GCGACGCCGA 
AGAACCTACT CAGATACAGA TTCTTGTAGT GATATTCCTC TTGAAGACCC AGATAGACCT 
GTTCACTGTT CAAAAAATAC ACTTAATGGA GATTTGGCAT CAGCAACCAT TCCTGAAGAA 
AGCAGACTTA TGGCCAAAAA ACAATCTGAA TCAGAAGATA CTCTTCCATC CTTCTCTTCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061964.3
CDS	414..1316
Translation	MEGVLYKWTNYLTGWQPRWFVLDNGILSYYDSQDDVCKGSKGSIKMAVCEIKVHSADNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTRTKKEKEISETSESLKTKMSELRLYCDLLMQQVHTIQEFVHHDENHSSPSAENMNEASSLLSATCNTFITTLEECVKIANAKFKPEMFQLHHPDPLVSPVSPSPVQMMKRSVSHPGSCSSERSSHSIKEPVSTLHRLSQRRRRTYSDTDSCSDIPLEDPDRPVHCSKNTLNGDLASATIPEESRLMAKKQSESEDTLPSFSS

Target ORF information:

RefSeq Version	NM_019091.4
Organism	Homo sapiens(human)
Definition	Homo sapiens pleckstrin homology domain containing A3 (PLEKHA3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019091.4

ORF Insert Sequence:

ATGGAGGGGG TGTTGTACAA GTGGACCAAC TATCTCACAG GCTGGCAGCC TCGTTGGTTT 
GTTTTAGATA ATGGAATCTT ATCCTACTAT GATTCACAAG ATGATGTTTG CAAAGGGAGC 
AAAGGAAGCA TAAAGATGGC AGTTTGTGAA ATTAAAGTTC ATTCAGCAGA CAACACAAGA 
ATGGAATTAA TCATTCCTGG AGAGCAGCAT TTCTACATGA AGGCAGTGAA TGCAGCTGAA 
AGACAGAGGT GGCTGGTCGC TCTGGGGAGC TCCAAAGCAT GTTTGACTGA TACAAGGACT 
AAAAAAGAAA AAGAAATAAG TGAAACCAGT GAATCGCTGA AAACCAAAAT GTCTGAACTT 
CGCCTCTACT GTGACCTCTT AATGCAGCAA GTTCATACAA TACAGGAATT TGTTCACCAT 
GATGAGAATC ATTCATCTCC TAGTGCAGAG AACATGAATG AAGCCTCTTC TCTGCTTAGT 
GCCACGTGTA ACACATTCAT CACAACGCTT GAGGAATGTG TGAAGATAGC CAATGCCAAG 
TTTAAACCTG AGATGTTTCA ACTGCACCAT CCGGATCCCT TAGTTTCTCC TGTGTCACCT 
TCTCCTGTTC AAATGATGAA GCGTTCTGTC AGCCACCCTG GTTCTTGCAG TTCAGAGAGG 
AGTAGCCACT CTATAAAAGA ACCAGTATCT ACACTTCACC GACTCTCCCA GCGACGCCGA 
AGAACCTACT CAGATACAGA TTCTTGTAGT GATATTCCTC TTGAAGACCC AGATAGACCT 
GTTCACTGTT CAAAAAATAC ACTTAATGGA GATTTGGCAT CAGCAACCAT TCCTGAAGAA 
AGCAGACTTA TGGCCAAAAA ACAATCTGAA TCAGAAGATA CTCTTCCATC CTTCTCTTCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PLEKHA3 ( NM_019091.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_061964.3 Homo sapiens pleckstrin homology domain containing A3 (PLEKHA3), mRNA.

Price & Availability↑

CloneID	OHu29448
Clone ID Related Accession (Same CDS sequence)	NM_019091.4 , NM_019091.3
Accession Version	NM_019091.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 903bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	pleckstrin homology domain-containing family A member 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BM794932.1, AK074209.1 and BC039812.1. On Oct 28, 2004 this sequence version replaced NM_019091.2. ##Evidence-Data-START## Transcript exon combination :: AF286162.1, SRR1660807.218785.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGGGGG TGTTGTACAA GTGGACCAAC TATCTCACAG GCTGGCAGCC TCGTTGGTTT 
GTTTTAGATA ATGGAATCTT ATCCTACTAT GATTCACAAG ATGATGTTTG CAAAGGGAGC 
AAAGGAAGCA TAAAGATGGC AGTTTGTGAA ATTAAAGTTC ATTCAGCAGA CAACACAAGA 
ATGGAATTAA TCATTCCTGG AGAGCAGCAT TTCTACATGA AGGCAGTGAA TGCAGCTGAA 
AGACAGAGGT GGCTGGTCGC TCTGGGGAGC TCCAAAGCAT GTTTGACTGA TACAAGGACT 
AAAAAAGAAA AAGAAATAAG TGAAACCAGT GAATCGCTGA AAACCAAAAT GTCTGAACTT 
CGCCTCTACT GTGACCTCTT AATGCAGCAA GTTCATACAA TACAGGAATT TGTTCACCAT 
GATGAGAATC ATTCATCTCC TAGTGCAGAG AACATGAATG AAGCCTCTTC TCTGCTTAGT 
GCCACGTGTA ACACATTCAT CACAACGCTT GAGGAATGTG TGAAGATAGC CAATGCCAAG 
TTTAAACCTG AGATGTTTCA ACTGCACCAT CCGGATCCCT TAGTTTCTCC TGTGTCACCT 
TCTCCTGTTC AAATGATGAA GCGTTCTGTC AGCCACCCTG GTTCTTGCAG TTCAGAGAGG 
AGTAGCCACT CTATAAAAGA ACCAGTATCT ACACTTCACC GACTCTCCCA GCGACGCCGA 
AGAACCTACT CAGATACAGA TTCTTGTAGT GATATTCCTC TTGAAGACCC AGATAGACCT 
GTTCACTGTT CAAAAAATAC ACTTAATGGA GATTTGGCAT CAGCAACCAT TCCTGAAGAA 
AGCAGACTTA TGGCCAAAAA ACAATCTGAA TCAGAAGATA CTCTTCCATC CTTCTCTTCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061964.3
CDS	399..1301
Translation	MEGVLYKWTNYLTGWQPRWFVLDNGILSYYDSQDDVCKGSKGSIKMAVCEIKVHSADNTRMELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTRTKKEKEISETSESLKTKMSELRLYCDLLMQQVHTIQEFVHHDENHSSPSAENMNEASSLLSATCNTFITTLEECVKIANAKFKPEMFQLHHPDPLVSPVSPSPVQMMKRSVSHPGSCSSERSSHSIKEPVSTLHRLSQRRRRTYSDTDSCSDIPLEDPDRPVHCSKNTLNGDLASATIPEESRLMAKKQSESEDTLPSFSS

Target ORF information:

RefSeq Version	NM_019091.3
Organism	Homo sapiens(human)
Definition	Homo sapiens pleckstrin homology domain containing A3 (PLEKHA3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019091.3

ORF Insert Sequence:

ATGGAGGGGG TGTTGTACAA GTGGACCAAC TATCTCACAG GCTGGCAGCC TCGTTGGTTT 
GTTTTAGATA ATGGAATCTT ATCCTACTAT GATTCACAAG ATGATGTTTG CAAAGGGAGC 
AAAGGAAGCA TAAAGATGGC AGTTTGTGAA ATTAAAGTTC ATTCAGCAGA CAACACAAGA 
ATGGAATTAA TCATTCCTGG AGAGCAGCAT TTCTACATGA AGGCAGTGAA TGCAGCTGAA 
AGACAGAGGT GGCTGGTCGC TCTGGGGAGC TCCAAAGCAT GTTTGACTGA TACAAGGACT 
AAAAAAGAAA AAGAAATAAG TGAAACCAGT GAATCGCTGA AAACCAAAAT GTCTGAACTT 
CGCCTCTACT GTGACCTCTT AATGCAGCAA GTTCATACAA TACAGGAATT TGTTCACCAT 
GATGAGAATC ATTCATCTCC TAGTGCAGAG AACATGAATG AAGCCTCTTC TCTGCTTAGT 
GCCACGTGTA ACACATTCAT CACAACGCTT GAGGAATGTG TGAAGATAGC CAATGCCAAG 
TTTAAACCTG AGATGTTTCA ACTGCACCAT CCGGATCCCT TAGTTTCTCC TGTGTCACCT 
TCTCCTGTTC AAATGATGAA GCGTTCTGTC AGCCACCCTG GTTCTTGCAG TTCAGAGAGG 
AGTAGCCACT CTATAAAAGA ACCAGTATCT ACACTTCACC GACTCTCCCA GCGACGCCGA 
AGAACCTACT CAGATACAGA TTCTTGTAGT GATATTCCTC TTGAAGACCC AGATAGACCT 
GTTCACTGTT CAAAAAATAC ACTTAATGGA GATTTGGCAT CAGCAACCAT TCCTGAAGAA 
AGCAGACTTA TGGCCAAAAA ACAATCTGAA TCAGAAGATA CTCTTCCATC CTTCTCTTCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PLEKHA3 ( XM_011511689.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011509991.1 Homo sapiens pleckstrin homology domain containing A3 (PLEKHA3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu36562
Clone ID Related Accession (Same CDS sequence)	XM_011511689.3 , XM_011511689.2
Accession Version	XM_011511689.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 723bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	pleckstrin homology domain-containing family A member 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011511689.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAATTAA TCATTCCTGG AGAGCAGCAT TTCTACATGA AGGCAGTGAA TGCAGCTGAA 
AGACAGAGGT GGCTGGTCGC TCTGGGGAGC TCCAAAGCAT GTTTGACTGA TACAAGGACT 
AAAAAAGAAA AAGAAATAAG TGAAACCAGT GAATCGCTGA AAACCAAAAT GTCTGAACTT 
CGCCTCTACT GTGACCTCTT AATGCAGCAA GTTCATACAA TACAGGAATT TGTTCACCAT 
GATGAGAATC ATTCATCTCC TAGTGCAGAG AACATGAATG AAGCCTCTTC TCTGCTTAGT 
GCCACGTGTA ACACATTCAT CACAACGCTT GAGGAATGTG TGAAGATAGC CAATGCCAAG 
TTTAAACCTG AGATGTTTCA ACTGCACCAT CCGGATCCCT TAGTTTCTCC TGTGTCACCT 
TCTCCTGTTC AAATGATGAA GCGTTCTGTC AGCCACCCTG GTTCTTGCAG TTCAGAGAGG 
AGTAGCCACT CTATAAAAGA ACCAGTATCT ACACTTCACC GACTCTCCCA GCGACGCCGA 
AGAACCTACT CAGATACAGA TTCTTGTAGT GATATTCCTC TTGAAGACCC AGATAGACCT 
GTTCACTGTT CAAAAAATAC ACTTAATGGA GATTTGGCAT CAGCAACCAT TCCTGAAGAA 
AGCAGACTTA TGGCCAAAAA ACAATCTGAA TCAGAAGATA CTCTTCCATC CTTCTCTTCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011509991.1
CDS	644..1366
Translation	MELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTRTKKEKEISETSESLKTKMSELRLYCDLLMQQVHTIQEFVHHDENHSSPSAENMNEASSLLSATCNTFITTLEECVKIANAKFKPEMFQLHHPDPLVSPVSPSPVQMMKRSVSHPGSCSSERSSHSIKEPVSTLHRLSQRRRRTYSDTDSCSDIPLEDPDRPVHCSKNTLNGDLASATIPEESRLMAKKQSESEDTLPSFSS

Target ORF information:

RefSeq Version	XM_011511689.3
Organism	Homo sapiens(human)
Definition	Homo sapiens pleckstrin homology domain containing A3 (PLEKHA3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011511689.3

ORF Insert Sequence:

ATGGAATTAA TCATTCCTGG AGAGCAGCAT TTCTACATGA AGGCAGTGAA TGCAGCTGAA 
AGACAGAGGT GGCTGGTCGC TCTGGGGAGC TCCAAAGCAT GTTTGACTGA TACAAGGACT 
AAAAAAGAAA AAGAAATAAG TGAAACCAGT GAATCGCTGA AAACCAAAAT GTCTGAACTT 
CGCCTCTACT GTGACCTCTT AATGCAGCAA GTTCATACAA TACAGGAATT TGTTCACCAT 
GATGAGAATC ATTCATCTCC TAGTGCAGAG AACATGAATG AAGCCTCTTC TCTGCTTAGT 
GCCACGTGTA ACACATTCAT CACAACGCTT GAGGAATGTG TGAAGATAGC CAATGCCAAG 
TTTAAACCTG AGATGTTTCA ACTGCACCAT CCGGATCCCT TAGTTTCTCC TGTGTCACCT 
TCTCCTGTTC AAATGATGAA GCGTTCTGTC AGCCACCCTG GTTCTTGCAG TTCAGAGAGG 
AGTAGCCACT CTATAAAAGA ACCAGTATCT ACACTTCACC GACTCTCCCA GCGACGCCGA 
AGAACCTACT CAGATACAGA TTCTTGTAGT GATATTCCTC TTGAAGACCC AGATAGACCT 
GTTCACTGTT CAAAAAATAC ACTTAATGGA GATTTGGCAT CAGCAACCAT TCCTGAAGAA 
AGCAGACTTA TGGCCAAAAA ACAATCTGAA TCAGAAGATA CTCTTCCATC CTTCTCTTCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PLEKHA3 ( XM_011511689.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011509991.1 Homo sapiens pleckstrin homology domain containing A3 (PLEKHA3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu36562
Clone ID Related Accession (Same CDS sequence)	XM_011511689.3 , XM_011511689.2
Accession Version	XM_011511689.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 723bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	pleckstrin homology domain-containing family A member 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011511689.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAATTAA TCATTCCTGG AGAGCAGCAT TTCTACATGA AGGCAGTGAA TGCAGCTGAA 
AGACAGAGGT GGCTGGTCGC TCTGGGGAGC TCCAAAGCAT GTTTGACTGA TACAAGGACT 
AAAAAAGAAA AAGAAATAAG TGAAACCAGT GAATCGCTGA AAACCAAAAT GTCTGAACTT 
CGCCTCTACT GTGACCTCTT AATGCAGCAA GTTCATACAA TACAGGAATT TGTTCACCAT 
GATGAGAATC ATTCATCTCC TAGTGCAGAG AACATGAATG AAGCCTCTTC TCTGCTTAGT 
GCCACGTGTA ACACATTCAT CACAACGCTT GAGGAATGTG TGAAGATAGC CAATGCCAAG 
TTTAAACCTG AGATGTTTCA ACTGCACCAT CCGGATCCCT TAGTTTCTCC TGTGTCACCT 
TCTCCTGTTC AAATGATGAA GCGTTCTGTC AGCCACCCTG GTTCTTGCAG TTCAGAGAGG 
AGTAGCCACT CTATAAAAGA ACCAGTATCT ACACTTCACC GACTCTCCCA GCGACGCCGA 
AGAACCTACT CAGATACAGA TTCTTGTAGT GATATTCCTC TTGAAGACCC AGATAGACCT 
GTTCACTGTT CAAAAAATAC ACTTAATGGA GATTTGGCAT CAGCAACCAT TCCTGAAGAA 
AGCAGACTTA TGGCCAAAAA ACAATCTGAA TCAGAAGATA CTCTTCCATC CTTCTCTTCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011509991.1
CDS	688..1410
Translation	MELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTRTKKEKEISETSESLKTKMSELRLYCDLLMQQVHTIQEFVHHDENHSSPSAENMNEASSLLSATCNTFITTLEECVKIANAKFKPEMFQLHHPDPLVSPVSPSPVQMMKRSVSHPGSCSSERSSHSIKEPVSTLHRLSQRRRRTYSDTDSCSDIPLEDPDRPVHCSKNTLNGDLASATIPEESRLMAKKQSESEDTLPSFSS

Target ORF information:

RefSeq Version	XM_011511689.2
Organism	Homo sapiens(human)
Definition	Homo sapiens pleckstrin homology domain containing A3 (PLEKHA3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011511689.2

ORF Insert Sequence:

ATGGAATTAA TCATTCCTGG AGAGCAGCAT TTCTACATGA AGGCAGTGAA TGCAGCTGAA 
AGACAGAGGT GGCTGGTCGC TCTGGGGAGC TCCAAAGCAT GTTTGACTGA TACAAGGACT 
AAAAAAGAAA AAGAAATAAG TGAAACCAGT GAATCGCTGA AAACCAAAAT GTCTGAACTT 
CGCCTCTACT GTGACCTCTT AATGCAGCAA GTTCATACAA TACAGGAATT TGTTCACCAT 
GATGAGAATC ATTCATCTCC TAGTGCAGAG AACATGAATG AAGCCTCTTC TCTGCTTAGT 
GCCACGTGTA ACACATTCAT CACAACGCTT GAGGAATGTG TGAAGATAGC CAATGCCAAG 
TTTAAACCTG AGATGTTTCA ACTGCACCAT CCGGATCCCT TAGTTTCTCC TGTGTCACCT 
TCTCCTGTTC AAATGATGAA GCGTTCTGTC AGCCACCCTG GTTCTTGCAG TTCAGAGAGG 
AGTAGCCACT CTATAAAAGA ACCAGTATCT ACACTTCACC GACTCTCCCA GCGACGCCGA 
AGAACCTACT CAGATACAGA TTCTTGTAGT GATATTCCTC TTGAAGACCC AGATAGACCT 
GTTCACTGTT CAAAAAATAC ACTTAATGGA GATTTGGCAT CAGCAACCAT TCCTGAAGAA 
AGCAGACTTA TGGCCAAAAA ACAATCTGAA TCAGAAGATA CTCTTCCATC CTTCTCTTCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Interaction of Fapp1 with Arf1 and PI4P at a membrane surface: an example of coincidence detection.
Structure (London, England : 1993)22(3)421-30(2014 Mar)
Liu Y,Kahn RA,Prestegard JH

Secondary structure and 1H, 13C, 15N resonance assignments of the Golgi-specific PH domain of FAPP1.
Biomolecular NMR assignments5(2)185-7(2011 Oct)
Lenoir M,Whittaker SB,Overduin M

Molecular basis of phosphatidylinositol 4-phosphate and ARF1 GTPase recognition by the FAPP1 pleckstrin homology (PH) domain.
The Journal of biological chemistry286(21)18650-7(2011 May)
He J,Scott JL,Heroux A,Roy S,Lenoir M,Overduin M,Stahelin RV,Kutateladze TG

Structural basis of wedging the Golgi membrane by FAPP pleckstrin homology domains.
EMBO reports11(4)279-84(2010 Apr)
Lenoir M,Coskun U,Grzybek M,Cao X,Buschhorn SB,James J,Simons K,Overduin M

Transcriptome analysis of human gastric cancer.
Mammalian genome : official journal of the International Mammalian Genome Society16(12)942-54(2005 Dec)
Oh JH,Yang JO,Hahn Y,Kim MR,Byun SS,Jeon YJ,Kim JM,Song KS,Noh SM,Kim S,Yoo HS,Kim YS,Kim NS

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PLEKHA3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム