TOR3A cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TOR3A
Entrez Gene ID	64222
Full Name	torsin family 3 member A
Synonyms	ADIR,ADIR2
General protein information	Preferred Names torsin family 3 member A Names torsin-3A ATP-dependant interferon response protein 1 ATP-dependant interferon responsive ATP-dependent interferon-responsive protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q25.2
Disorder MIM:	607555

mRNA and Protein(s)

mRNA	Protein	Name
NM_022371.4	NP_071766.2	torsin-3A precursor
NM_022371.3	NP_071766.2	torsin-3A precursor

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	TOR3A	XP_422270.1
Homo sapiens (human)	TOR3A	NP_071766.2
Pan troglodytes (chimpanzee)	TOR3A	XP_514028.2
	TOR3A	XP_001115512.1
Rattus norvegicus (Norway rat)	Tor3a	NP_001009683.1
Bos taurus (cattle)	TOR3A	NP_001073845.1
Danio rerio (zebrafish)	tor3a	NP_001121738.1
Canis lupus familiaris (dog)	TOR3A	XP_005623020.1
Mus musculus (house mouse)	Tor3a	NP_075630.2
Xenopus tropicalis (tropical clawed frog)	tor3a	NP_001025592.2

Gene Ontology
Bibliography

Related articles in PubMed

Regulation of Torsin ATPases by LAP1 and LULL1.
Zhao C, Brown RS, Chase AR, Eisele MR, Schlieker C
Proceedings of the National Academy of Sciences of the United States of America110(17)E1545-54(2013 Apr)

New genetic associations detected in a host response study to hepatitis B vaccine.
Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M
Genes and immunity11(3)232-8(2010 Apr)

Relative tissue expression of homologous torsinB correlates with the neuronal specific importance of DYT1 dystonia-associated torsinA.
Jungwirth M, Dear ML, Brown P, Holbrook K, Goodchild R
Human molecular genetics19(5)888-900(2010 Mar)

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal of proteome research8(3)1304-14(2009 Mar)

Molecular cloning of ADIR, a novel interferon responsive gene encoding a protein related to the torsins.
Dron M, Meritet JF, Dandoy-Dron F, Meyniel JP, Maury C, Tovey MG
Genomics79(3)315-25(2002 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

Observational study of gene-disease association. (HuGE Navigator)
Title: New genetic associations detected in a host response study to hepatitis B vaccine.

The following TOR3A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TOR3A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu02103	NM_022371.4 Latest version!	Homo sapiens torsin family 3 member A (TOR3A), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
View Old Accession Versions >>
OHu02103	NM_022371.3	Homo sapiens torsin family 3 member A (TOR3A), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TOR3A ( NM_022371.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_071766.2 Homo sapiens torsin family 3 member A (TOR3A), mRNA.

Price & Availability↑

CloneID	OHu02103
Clone ID Related Accession (Same CDS sequence)	NM_022371.4 , NM_022371.3
Accession Version	NM_022371.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1194bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	torsin-3A precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA942161.1, AJ299403.1 and BC011746.1. On Nov 22, 2018 this sequence version replaced NM_022371.3. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.818303.1, ERR279837.1851.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000367627.8/ ENSP00000356599.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCTTCGCG GTCCGTGGCG CCAGCTTTGG CTCTTTTTCC TGCTGCTGCT CCCGGGCGCG 
CCTGAGCCCC GCGGCGCCTC CAGGCCGTGG GAGGGAACCG ACGAGCCGGG CTCGGCCTGG 
GCCTGGCCGG GCTTCCAGCG CCTGCAGGAG CAGCTCAGGG CGGCGGGTGC CCTCTCCAAG 
CGGTACTGGA CGCTCTTCAG CTGCCAGGTG TGGCCCGACG ACTGTGACGA GGACGAGGAG 
GCAGCCACGG GGCCCCTGGG CTGGCGCCTT CCTCTGTTGG GCCAGCGGTA CCTGGACCTC 
CTGACCACGT GGTACTGCAG CTTCAAAGAC TGCTGCCCTA GAGGGGATTG CAGAATCTCC 
AACAACTTTA CAGGCTTAGA GTGGGACCTG AATGTGCGGC TGCATGGCCA GCATTTGGTC 
CAGCAGCTGG TCCTAAGAAC AGTGAGGGGC TACTTAGAGA CGCCCCAGCC AGAAAAGGCC 
CTTGCTCTGT CGTTCCACGG CTGGTCTGGC ACAGGCAAGA ACTTCGTGGC ACGGATGCTG 
GTGGAGAACC TGTATCGGGA CGGGCTGATG AGTGACTGTG TCAGGATGTT CATCGCCACG 
TTCCACTTTC CTCACCCCAA ATATGTGGAC CTGTACAAGG AGCAGCTGAT GAGCCAGATC 
CGGGAGACGC AGCAGCTCTG CCACCAGACC CTGTTCATCT TCGATGAAGC GGAGAAGCTG 
CACCCAGGGC TGCTGGAGGT CCTTGGGCCA CACTTAGAAC GCCGGGCCCC TGAGGGCCAC 
AGGGCTGAGT CTCCATGGAC TATCTTTCTG TTTCTCAGTA ATCTCAGGGG CGATATAATC 
AATGAGGTGG TCCTAAAGTT GCTCAAGGCT GGATGGTCCC GGGAAGAAAT TACGATGGAA 
CACCTGGAGC CCCACCTCCA GGCGGAGATT GTGGAGACCA TAGACAATGG CTTTGGCCAC 
AGCCGTCTTG TGAAGGAAAA CCTGATTGAC TACTTCATCC CCTTCCTGCC TTTGGAGTAC 
CGTCACGTGA GGCTGTGTGC ACGGGATGCC TTCCTGAGCC AGGAGCTCCT GTATAAAGAA 
GAGACACTGG ATGAAATAGC CCAGATGATG GTGTATGTCC CCAAGGAGGA ACAACTCTTT 
TCTTCCCAGG GCTGCAAGTC TATTTCCCAG AGGATTAACT ACTTCCTGTC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071766.2
CDS	60..1253
Translation	MLRGPWRQLWLFFLLLLPGAPEPRGASRPWEGTDEPGSAWAWPGFQRLQEQLRAAGALSKRYWTLFSCQVWPDDCDEDEEAATGPLGWRLPLLGQRYLDLLTTWYCSFKDCCPRGDCRISNNFTGLEWDLNVRLHGQHLVQQLVLRTVRGYLETPQPEKALALSFHGWSGTGKNFVARMLVENLYRDGLMSDCVRMFIATFHFPHPKYVDLYKEQLMSQIRETQQLCHQTLFIFDEAEKLHPGLLEVLGPHLERRAPEGHRAESPWTIFLFLSNLRGDIINEVVLKLLKAGWSREEITMEHLEPHLQAEIVETIDNGFGHSRLVKENLIDYFIPFLPLEYRHVRLCARDAFLSQELLYKEETLDEIAQMMVYVPKEEQLFSSQGCKSISQRINYFLS

Target ORF information:

RefSeq Version	NM_022371.4
Organism	Homo sapiens(human)
Definition	Homo sapiens torsin family 3 member A (TOR3A), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022371.4

ORF Insert Sequence:

ATGCTTCGCG GTCCGTGGCG CCAGCTTTGG CTCTTTTTCC TGCTGCTGCT CCCGGGCGCG 
CCTGAGCCCC GCGGCGCCTC CAGGCCGTGG GAGGGAACCG ACGAGCCGGG CTCGGCCTGG 
GCCTGGCCGG GCTTCCAGCG CCTGCAGGAG CAGCTCAGGG CGGCGGGTGC CCTCTCCAAG 
CGGTACTGGA CGCTCTTCAG CTGCCAGGTG TGGCCCGACG ACTGTGACGA GGACGAGGAG 
GCAGCCACGG GGCCCCTGGG CTGGCGCCTT CCTCTGTTGG GCCAGCGGTA CCTGGACCTC 
CTGACCACGT GGTACTGCAG CTTCAAAGAC TGCTGCCCTA GAGGGGATTG CAGAATCTCC 
AACAACTTTA CAGGCTTAGA GTGGGACCTG AATGTGCGGC TGCATGGCCA GCATTTGGTC 
CAGCAGCTGG TCCTAAGAAC AGTGAGGGGC TACTTAGAGA CGCCCCAGCC AGAAAAGGCC 
CTTGCTCTGT CGTTCCACGG CTGGTCTGGC ACAGGCAAGA ACTTCGTGGC ACGGATGCTG 
GTGGAGAACC TGTATCGGGA CGGGCTGATG AGTGACTGTG TCAGGATGTT CATCGCCACG 
TTCCACTTTC CTCACCCCAA ATATGTGGAC CTGTACAAGG AGCAGCTGAT GAGCCAGATC 
CGGGAGACGC AGCAGCTCTG CCACCAGACC CTGTTCATCT TCGATGAAGC GGAGAAGCTG 
CACCCAGGGC TGCTGGAGGT CCTTGGGCCA CACTTAGAAC GCCGGGCCCC TGAGGGCCAC 
AGGGCTGAGT CTCCATGGAC TATCTTTCTG TTTCTCAGTA ATCTCAGGGG CGATATAATC 
AATGAGGTGG TCCTAAAGTT GCTCAAGGCT GGATGGTCCC GGGAAGAAAT TACGATGGAA 
CACCTGGAGC CCCACCTCCA GGCGGAGATT GTGGAGACCA TAGACAATGG CTTTGGCCAC 
AGCCGTCTTG TGAAGGAAAA CCTGATTGAC TACTTCATCC CCTTCCTGCC TTTGGAGTAC 
CGTCACGTGA GGCTGTGTGC ACGGGATGCC TTCCTGAGCC AGGAGCTCCT GTATAAAGAA 
GAGACACTGG ATGAAATAGC CCAGATGATG GTGTATGTCC CCAAGGAGGA ACAACTCTTT 
TCTTCCCAGG GCTGCAAGTC TATTTCCCAG AGGATTAACT ACTTCCTGTC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TOR3A ( NM_022371.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_071766.2 Homo sapiens torsin family 3 member A (TOR3A), mRNA.

Price & Availability↑

CloneID	OHu02103
Clone ID Related Accession (Same CDS sequence)	NM_022371.4 , NM_022371.3
Accession Version	NM_022371.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1194bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	torsin-3A precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA942161.1, AJ299403.1 and BC011746.1. On Oct 7, 2006 this sequence version replaced NM_022371.2. ##Evidence-Data-START## Transcript exon combination :: BC001085.1, SRR1660809.97635.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGCTTCGCG GTCCGTGGCG CCAGCTTTGG CTCTTTTTCC TGCTGCTGCT CCCGGGCGCG 
CCTGAGCCCC GCGGCGCCTC CAGGCCGTGG GAGGGAACCG ACGAGCCGGG CTCGGCCTGG 
GCCTGGCCGG GCTTCCAGCG CCTGCAGGAG CAGCTCAGGG CGGCGGGTGC CCTCTCCAAG 
CGGTACTGGA CGCTCTTCAG CTGCCAGGTG TGGCCCGACG ACTGTGACGA GGACGAGGAG 
GCAGCCACGG GGCCCCTGGG CTGGCGCCTT CCTCTGTTGG GCCAGCGGTA CCTGGACCTC 
CTGACCACGT GGTACTGCAG CTTCAAAGAC TGCTGCCCTA GAGGGGATTG CAGAATCTCC 
AACAACTTTA CAGGCTTAGA GTGGGACCTG AATGTGCGGC TGCATGGCCA GCATTTGGTC 
CAGCAGCTGG TCCTAAGAAC AGTGAGGGGC TACTTAGAGA CGCCCCAGCC AGAAAAGGCC 
CTTGCTCTGT CGTTCCACGG CTGGTCTGGC ACAGGCAAGA ACTTCGTGGC ACGGATGCTG 
GTGGAGAACC TGTATCGGGA CGGGCTGATG AGTGACTGTG TCAGGATGTT CATCGCCACG 
TTCCACTTTC CTCACCCCAA ATATGTGGAC CTGTACAAGG AGCAGCTGAT GAGCCAGATC 
CGGGAGACGC AGCAGCTCTG CCACCAGACC CTGTTCATCT TCGATGAAGC GGAGAAGCTG 
CACCCAGGGC TGCTGGAGGT CCTTGGGCCA CACTTAGAAC GCCGGGCCCC TGAGGGCCAC 
AGGGCTGAGT CTCCATGGAC TATCTTTCTG TTTCTCAGTA ATCTCAGGGG CGATATAATC 
AATGAGGTGG TCCTAAAGTT GCTCAAGGCT GGATGGTCCC GGGAAGAAAT TACGATGGAA 
CACCTGGAGC CCCACCTCCA GGCGGAGATT GTGGAGACCA TAGACAATGG CTTTGGCCAC 
AGCCGTCTTG TGAAGGAAAA CCTGATTGAC TACTTCATCC CCTTCCTGCC TTTGGAGTAC 
CGTCACGTGA GGCTGTGTGC ACGGGATGCC TTCCTGAGCC AGGAGCTCCT GTATAAAGAA 
GAGACACTGG ATGAAATAGC CCAGATGATG GTGTATGTCC CCAAGGAGGA ACAACTCTTT 
TCTTCCCAGG GCTGCAAGTC TATTTCCCAG AGGATTAACT ACTTCCTGTC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071766.2
CDS	153..1346
Translation	MLRGPWRQLWLFFLLLLPGAPEPRGASRPWEGTDEPGSAWAWPGFQRLQEQLRAAGALSKRYWTLFSCQVWPDDCDEDEEAATGPLGWRLPLLGQRYLDLLTTWYCSFKDCCPRGDCRISNNFTGLEWDLNVRLHGQHLVQQLVLRTVRGYLETPQPEKALALSFHGWSGTGKNFVARMLVENLYRDGLMSDCVRMFIATFHFPHPKYVDLYKEQLMSQIRETQQLCHQTLFIFDEAEKLHPGLLEVLGPHLERRAPEGHRAESPWTIFLFLSNLRGDIINEVVLKLLKAGWSREEITMEHLEPHLQAEIVETIDNGFGHSRLVKENLIDYFIPFLPLEYRHVRLCARDAFLSQELLYKEETLDEIAQMMVYVPKEEQLFSSQGCKSISQRINYFLS

Target ORF information:

RefSeq Version	NM_022371.3
Organism	Homo sapiens(human)
Definition	Homo sapiens torsin family 3 member A (TOR3A), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022371.3

ORF Insert Sequence:

ATGCTTCGCG GTCCGTGGCG CCAGCTTTGG CTCTTTTTCC TGCTGCTGCT CCCGGGCGCG 
CCTGAGCCCC GCGGCGCCTC CAGGCCGTGG GAGGGAACCG ACGAGCCGGG CTCGGCCTGG 
GCCTGGCCGG GCTTCCAGCG CCTGCAGGAG CAGCTCAGGG CGGCGGGTGC CCTCTCCAAG 
CGGTACTGGA CGCTCTTCAG CTGCCAGGTG TGGCCCGACG ACTGTGACGA GGACGAGGAG 
GCAGCCACGG GGCCCCTGGG CTGGCGCCTT CCTCTGTTGG GCCAGCGGTA CCTGGACCTC 
CTGACCACGT GGTACTGCAG CTTCAAAGAC TGCTGCCCTA GAGGGGATTG CAGAATCTCC 
AACAACTTTA CAGGCTTAGA GTGGGACCTG AATGTGCGGC TGCATGGCCA GCATTTGGTC 
CAGCAGCTGG TCCTAAGAAC AGTGAGGGGC TACTTAGAGA CGCCCCAGCC AGAAAAGGCC 
CTTGCTCTGT CGTTCCACGG CTGGTCTGGC ACAGGCAAGA ACTTCGTGGC ACGGATGCTG 
GTGGAGAACC TGTATCGGGA CGGGCTGATG AGTGACTGTG TCAGGATGTT CATCGCCACG 
TTCCACTTTC CTCACCCCAA ATATGTGGAC CTGTACAAGG AGCAGCTGAT GAGCCAGATC 
CGGGAGACGC AGCAGCTCTG CCACCAGACC CTGTTCATCT TCGATGAAGC GGAGAAGCTG 
CACCCAGGGC TGCTGGAGGT CCTTGGGCCA CACTTAGAAC GCCGGGCCCC TGAGGGCCAC 
AGGGCTGAGT CTCCATGGAC TATCTTTCTG TTTCTCAGTA ATCTCAGGGG CGATATAATC 
AATGAGGTGG TCCTAAAGTT GCTCAAGGCT GGATGGTCCC GGGAAGAAAT TACGATGGAA 
CACCTGGAGC CCCACCTCCA GGCGGAGATT GTGGAGACCA TAGACAATGG CTTTGGCCAC 
AGCCGTCTTG TGAAGGAAAA CCTGATTGAC TACTTCATCC CCTTCCTGCC TTTGGAGTAC 
CGTCACGTGA GGCTGTGTGC ACGGGATGCC TTCCTGAGCC AGGAGCTCCT GTATAAAGAA 
GAGACACTGG ATGAAATAGC CCAGATGATG GTGTATGTCC CCAAGGAGGA ACAACTCTTT 
TCTTCCCAGG GCTGCAAGTC TATTTCCCAG AGGATTAACT ACTTCCTGTC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Regulation of Torsin ATPases by LAP1 and LULL1.
Proceedings of the National Academy of Sciences of the United States of America110(17)E1545-54(2013 Apr)
Zhao C,Brown RS,Chase AR,Eisele MR,Schlieker C

New genetic associations detected in a host response study to hepatitis B vaccine.
Genes and immunity11(3)232-8(2010 Apr)
Davila S,Froeling FE,Tan A,Bonnard C,Boland GJ,Snippe H,Hibberd ML,Seielstad M

Relative tissue expression of homologous torsinB correlates with the neuronal specific importance of DYT1 dystonia-associated torsinA.
Human molecular genetics19(5)888-900(2010 Mar)
Jungwirth M,Dear ML,Brown P,Holbrook K,Goodchild R

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Journal of proteome research8(3)1304-14(2009 Mar)
Gonzalez-Begne M,Lu B,Han X,Hagen FK,Hand AR,Melvin JE,Yates JR

Molecular cloning of ADIR, a novel interferon responsive gene encoding a protein related to the torsins.
Genomics79(3)315-25(2002 Mar)
Dron M,Meritet JF,Dandoy-Dron F,Meyniel JP,Maury C,Tovey MG