BLOC1S5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	BLOC1S5
Entrez Gene ID	63915
Full Name	biogenesis of lysosomal organelles complex 1 subunit 5
Synonyms	BLOS5,MU,MUTED
General protein information	Preferred Names biogenesis of lysosomal organelles complex 1 subunit 5 Names biogenesis of lysosome-related organelles complex 1 subunit 5 BLOC-1 subunit 5 biogenesis of lysosomal organelles complex-1, subunit 5, muted muted homolog protein Muted homolog
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6p24.3
Summary	This gene encodes a component of BLOC-1 (biogenesis of lysosome-related organelles complex 1). Components of this complex are involved in the biogenesis of organelles such as melanosomes and platelet-dense granules. A mouse model for Hermansky-Pudlak Syndrome is mutated in the murine version of this gene. Alternative splicing results in multiple transcript variants. Read-through transcription exists between this gene and the upstream EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1) gene, as well as with the downstream TXNDC5 (thioredoxin domain containing 5) gene. [provided by RefSeq, Dec 2010].
Disorder MIM:	607289

mRNA and Protein(s)

mRNA	Protein	Name
NM_201280.2	NP_958437.1	biogenesis of lysosome-related organelles complex 1 subunit 5 isoform 1
NM_201280.3	NP_958437.1	biogenesis of lysosome-related organelles complex 1 subunit 5 isoform 1
NM_001199322.1	NP_001186251.1	biogenesis of lysosome-related organelles complex 1 subunit 5 isoform 2
NM_001199323.1	NP_001186252.1	biogenesis of lysosome-related organelles complex 1 subunit 5 isoform 3

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	BLOC1S5	NP_001006373.1
Xenopus tropicalis (tropical clawed frog)	bloc1s5	NP_001107140.1
Homo sapiens (human)	BLOC1S5	NP_958437.1
Pan troglodytes (chimpanzee)	MUTED	XP_001166060.1
	MUTED	XP_002803634.1
Canis lupus familiaris (dog)	BLOC1S5	XP_851825.3
Danio rerio (zebrafish)	bloc1s5	NP_001025237.1
Mus musculus (house mouse)	Bloc1s5	NP_620702.1
Rattus norvegicus (Norway rat)	Bloc1s5	NP_001100817.1

Gene Ontology
Bibliography

Related articles in PubMed

Assembly and architecture of biogenesis of lysosome-related organelles complex-1 (BLOC-1).
Lee HH, Nemecek D, Schindler C, Smith WJ, Ghirlando R, Steven AC, Bonifacino JS, Hurley JH
The Journal of biological chemistry287(8)5882-90(2012 Feb)

An integrative method for scoring candidate genes from association studies: application to warfarin dosing.
Tatonetti NP, Dudley JT, Sagreiya H, Butte AJ, Altman RB
BMC bioinformatics11 Suppl 9S9(2010 Oct)

Dysbindin (DTNBP1) and the biogenesis of lysosome-related organelles complex 1 (BLOC-1): main and epistatic gene effects are potential contributors to schizophrenia susceptibility.
Morris DW, Murphy K, Kenny N, Purcell SM, McGhee KA, Schwaiger S, Nangle JM, Donohoe G, Clarke S, Scully P, Quinn J, Meagher D, Baldwin P, Crumlish N, O'Callaghan E, Waddington JL, Gill M, Corvin AP
Biological psychiatry63(1)24-31(2008 Jan)

BLOC-1 is required for cargo-specific sorting from vacuolar early endosomes toward lysosome-related organelles.
Setty SR, Tenza D, Truschel ST, Chou E, Sviderskaya EV, Theos AC, Lamoreux ML, Di Pietro SM, Starcevic M, Bennett DC, Dell'Angelica EC, Raposo G, Marks MS
Molecular biology of the cell18(3)768-80(2007 Mar)

Transcriptome analysis of human gastric cancer.
Oh JH, Yang JO, Hahn Y, Kim MR, Byun SS, Jeon YJ, Kim JM, Song KS, Noh SM, Kim S, Yoo HS, Kim YS, Kim NS
Mammalian genome : official journal of the International Mammalian Genome Society16(12)942-54(2005 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association. (HuGE Navigator)
Title: An integrative method for scoring candidate genes from association studies: application to warfarin dosing.

Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
Title: Dysbindin (DTNBP1) and the biogenesis of lysosome-related organelles complex 1 (BLOC-1): main and epistatic gene effects are potential contributors to schizophrenia susceptibility.

The following BLOC1S5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BLOC1S5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu00786	NM_201280.3 Latest version!	Homo sapiens biogenesis of lysosomal organelles complex 1 subunit 5 (BLOC1S5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu08507	NM_001199322.1 Latest version!	Homo sapiens biogenesis of lysosomal organelles complex 1 subunit 5 (BLOC1S5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu01683	NM_001199323.1 Latest version!	Homo sapiens biogenesis of lysosomal organelles complex 1 subunit 5 (BLOC1S5), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu00786	NM_201280.2	Homo sapiens biogenesis of lysosomal organelles complex 1 subunit 5 (BLOC1S5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

BLOC1S5 ( NM_201280.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_958437.1 Homo sapiens biogenesis of lysosomal organelles complex 1 subunit 5 (BLOC1S5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu00786
Clone ID Related Accession (Same CDS sequence)	NM_201280.2 , NM_201280.3
Accession Version	NM_201280.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 564bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	biogenesis of lysosome-related organelles complex 1 subunit 5 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF426434.1, AL096800.20 and AA653396.1. On Dec 3, 2010 this sequence version replaced NM_201280.1. Transcript Variant: This variant (1) encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF426434.1, SRR1803611.76591.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGTGGCG GAGGGACAGA GACCCCTGTG GGTTGTGAGG CCGCCCCGGG CGGTGGCAGC 
AAGAAGAGGG ACTCCCTGGG GACTGCGGGC TCAGCGCACC TCATTATCAA GGATCTTGGA 
GAAATTCATT CAAGGCTTTT GGATCACAGA CCAGTTATTC AAGGTGAAAC TCGTTATTTT 
GTAAAAGAAT TTGAAGAAAA ACGTGGTCTT CGAGAAATGC GAGTTCTTGA AAATTTGAAG 
AACATGATCC ATGAAACAAA TGAACATACT CTTCCCAAAT GTAGAGACAC AATGCGGGAC 
AGCCTCAGCC AGGTTCTCCA GAGATTGCAA GCAGCTAATG ACTCAGTCTG TAGACTCCAA 
CAGAGGGAAC AGGAACGAAA AAAGATTCAT AGTGACCACT TAGTAGCTAG TGAGAAACAG 
CATATGCTCC AGTGGGACAA CTTCATGAAG GAGCAACCCA ACAAAAGGGC TGAAGTGGAT 
GAAGAGCACA GAAAAGCCAT GGAAAGGCTT AAAGAACAAT ATGCTGAGAT GGAGAAGGAC 
CTAGCGAAAT TTTCAACCTT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_958437.1
CDS	39..602
Translation	MSGGGTETPVGCEAAPGGGSKKRDSLGTAGSAHLIIKDLGEIHSRLLDHRPVIQGETRYFVKEFEEKRGLREMRVLENLKNMIHETNEHTLPKCRDTMRDSLSQVLQRLQAANDSVCRLQQREQERKKIHSDHLVASEKQHMLQWDNFMKEQPNKRAEVDEEHRKAMERLKEQYAEMEKDLAKFSTF

Target ORF information:

RefSeq Version	NM_201280.2
Organism	Homo sapiens(human)
Definition	Homo sapiens biogenesis of lysosomal organelles complex 1 subunit 5 (BLOC1S5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_201280.2

ORF Insert Sequence:

ATGAGTGGCG GAGGGACAGA GACCCCTGTG GGTTGTGAGG CCGCCCCGGG CGGTGGCAGC 
AAGAAGAGGG ACTCCCTGGG GACTGCGGGC TCAGCGCACC TCATTATCAA GGATCTTGGA 
GAAATTCATT CAAGGCTTTT GGATCACAGA CCAGTTATTC AAGGTGAAAC TCGTTATTTT 
GTAAAAGAAT TTGAAGAAAA ACGTGGTCTT CGAGAAATGC GAGTTCTTGA AAATTTGAAG 
AACATGATCC ATGAAACAAA TGAACATACT CTTCCCAAAT GTAGAGACAC AATGCGGGAC 
AGCCTCAGCC AGGTTCTCCA GAGATTGCAA GCAGCTAATG ACTCAGTCTG TAGACTCCAA 
CAGAGGGAAC AGGAACGAAA AAAGATTCAT AGTGACCACT TAGTAGCTAG TGAGAAACAG 
CATATGCTCC AGTGGGACAA CTTCATGAAG GAGCAACCCA ACAAAAGGGC TGAAGTGGAT 
GAAGAGCACA GAAAAGCCAT GGAAAGGCTT AAAGAACAAT ATGCTGAGAT GGAGAAGGAC 
CTAGCGAAAT TTTCAACCTT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BLOC1S5 ( NM_201280.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_958437.1 Homo sapiens biogenesis of lysosomal organelles complex 1 subunit 5 (BLOC1S5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu00786
Clone ID Related Accession (Same CDS sequence)	NM_201280.2 , NM_201280.3
Accession Version	NM_201280.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 564bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-16
Organism	Homo sapiens(human)
Product	biogenesis of lysosome-related organelles complex 1 subunit 5 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF426434.1, AL096800.20 and AA653396.1. On Nov 22, 2018 this sequence version replaced NM_201280.2. Transcript Variant: This variant (1) encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.120971.1, SRR1660809.176095.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000397457.7/ ENSP00000380598.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAGTGGCG GAGGGACAGA GACCCCTGTG GGTTGTGAGG CCGCCCCGGG CGGTGGCAGC 
AAGAAGAGGG ACTCCCTGGG GACTGCGGGC TCAGCGCACC TCATTATCAA GGATCTTGGA 
GAAATTCATT CAAGGCTTTT GGATCACAGA CCAGTTATTC AAGGTGAAAC TCGTTATTTT 
GTAAAAGAAT TTGAAGAAAA ACGTGGTCTT CGAGAAATGC GAGTTCTTGA AAATTTGAAG 
AACATGATCC ATGAAACAAA TGAACATACT CTTCCCAAAT GTAGAGACAC AATGCGGGAC 
AGCCTCAGCC AGGTTCTCCA GAGATTGCAA GCAGCTAATG ACTCAGTCTG TAGACTCCAA 
CAGAGGGAAC AGGAACGAAA AAAGATTCAT AGTGACCACT TAGTAGCTAG TGAGAAACAG 
CATATGCTCC AGTGGGACAA CTTCATGAAG GAGCAACCCA ACAAAAGGGC TGAAGTGGAT 
GAAGAGCACA GAAAAGCCAT GGAAAGGCTT AAAGAACAAT ATGCTGAGAT GGAGAAGGAC 
CTAGCGAAAT TTTCAACCTT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_958437.1
CDS	14..577
Translation	MSGGGTETPVGCEAAPGGGSKKRDSLGTAGSAHLIIKDLGEIHSRLLDHRPVIQGETRYFVKEFEEKRGLREMRVLENLKNMIHETNEHTLPKCRDTMRDSLSQVLQRLQAANDSVCRLQQREQERKKIHSDHLVASEKQHMLQWDNFMKEQPNKRAEVDEEHRKAMERLKEQYAEMEKDLAKFSTF

Target ORF information:

RefSeq Version	NM_201280.3
Organism	Homo sapiens(human)
Definition	Homo sapiens biogenesis of lysosomal organelles complex 1 subunit 5 (BLOC1S5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_201280.3

ORF Insert Sequence:

ATGAGTGGCG GAGGGACAGA GACCCCTGTG GGTTGTGAGG CCGCCCCGGG CGGTGGCAGC 
AAGAAGAGGG ACTCCCTGGG GACTGCGGGC TCAGCGCACC TCATTATCAA GGATCTTGGA 
GAAATTCATT CAAGGCTTTT GGATCACAGA CCAGTTATTC AAGGTGAAAC TCGTTATTTT 
GTAAAAGAAT TTGAAGAAAA ACGTGGTCTT CGAGAAATGC GAGTTCTTGA AAATTTGAAG 
AACATGATCC ATGAAACAAA TGAACATACT CTTCCCAAAT GTAGAGACAC AATGCGGGAC 
AGCCTCAGCC AGGTTCTCCA GAGATTGCAA GCAGCTAATG ACTCAGTCTG TAGACTCCAA 
CAGAGGGAAC AGGAACGAAA AAAGATTCAT AGTGACCACT TAGTAGCTAG TGAGAAACAG 
CATATGCTCC AGTGGGACAA CTTCATGAAG GAGCAACCCA ACAAAAGGGC TGAAGTGGAT 
GAAGAGCACA GAAAAGCCAT GGAAAGGCTT AAAGAACAAT ATGCTGAGAT GGAGAAGGAC 
CTAGCGAAAT TTTCAACCTT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BLOC1S5 ( NM_001199322.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001186251.1 Homo sapiens biogenesis of lysosomal organelles complex 1 subunit 5 (BLOC1S5), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu08507
Clone ID Related Accession (Same CDS sequence)	NM_001199322.1
Accession Version	NM_001199322.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 372bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Homo sapiens(human)
Product	biogenesis of lysosome-related organelles complex 1 subunit 5 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA635930.1, BC119645.1, AL096800.20 and AA653396.1. Transcript Variant: This variant (2) includes an additional internal exon, resulting in the use of an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct and shorter N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.241951.1, BC119645.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAAAAAC GTGGTCTTCG AGAAATGCGA GTTCTTGAAA ATTTGAAGAA CATGATCCAT 
GAAACAAATG AACATACTCT TCCCAAATGT AGAGACACAA TGCGGGACAG CCTCAGCCAG 
GTTCTCCAGA GATTGCAAGC AGCTAATGAC TCAGTCTGTA GACTCCAACA GAGGGAACAG 
GAACGAAAAA AGATTCATAG TGACCACTTA GTAGCTAGTG AGAAACAGCA TATGCTCCAG 
TGGGACAACT TCATGAAGGA GCAACCCAAC AAAAGGGCTG AAGTGGATGA AGAGCACAGA 
AAAGCCATGG AAAGGCTTAA AGAACAATAT GCTGAGATGG AGAAGGACCT AGCGAAATTT 
TCAACCTTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001186251.1
CDS	334..705
Translation	MEKRGLREMRVLENLKNMIHETNEHTLPKCRDTMRDSLSQVLQRLQAANDSVCRLQQREQERKKIHSDHLVASEKQHMLQWDNFMKEQPNKRAEVDEEHRKAMERLKEQYAEMEKDLAKFSTF

Target ORF information:

RefSeq Version	NM_001199322.1
Organism	Homo sapiens(human)
Definition	Homo sapiens biogenesis of lysosomal organelles complex 1 subunit 5 (BLOC1S5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001199322.1

ORF Insert Sequence:

ATGGAAAAAC GTGGTCTTCG AGAAATGCGA GTTCTTGAAA ATTTGAAGAA CATGATCCAT 
GAAACAAATG AACATACTCT TCCCAAATGT AGAGACACAA TGCGGGACAG CCTCAGCCAG 
GTTCTCCAGA GATTGCAAGC AGCTAATGAC TCAGTCTGTA GACTCCAACA GAGGGAACAG 
GAACGAAAAA AGATTCATAG TGACCACTTA GTAGCTAGTG AGAAACAGCA TATGCTCCAG 
TGGGACAACT TCATGAAGGA GCAACCCAAC AAAAGGGCTG AAGTGGATGA AGAGCACAGA 
AAAGCCATGG AAAGGCTTAA AGAACAATAT GCTGAGATGG AGAAGGACCT AGCGAAATTT 
TCAACCTTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BLOC1S5 ( NM_001199323.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001186252.1 Homo sapiens biogenesis of lysosomal organelles complex 1 subunit 5 (BLOC1S5), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu01683
Clone ID Related Accession (Same CDS sequence)	NM_001199323.1
Accession Version	NM_001199323.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 273bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-16
Organism	Homo sapiens(human)
Product	biogenesis of lysosome-related organelles complex 1 subunit 5 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA635930.1, BM829259.1, AL096800.20 and AA653396.1. Transcript Variant: This variant (3) lacks an alternate exon that results in a frameshift in the 3' coding region, compared to variant 1. The encoded isoform (3) has a distinct and shorter C-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.412987.1, SRR1660807.196967.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1970526 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGTGGCG GAGGGACAGA GACCCCTGTG GGTTGTGAGG CCGCCCCGGG CGGTGGCAGC 
AAGAAGAGGG ACTCCCTGGG GACTGCGGGC TCAGCGCACC TCATTATCAA GGATCTTGGA 
GAAATTCATT CAAGGCTTTT GGATCACAGA CCAGTTATTC AAGGTGAAAC TCGTTATTTT 
GTAAAAGAAT TTGAATGCAA GCAGCTAATG ACTCAGTCTG TAGACTCCAA CAGAGGGAAC 
AGGAACGAAA AAAGATTCAT AGTGACCACT TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001186252.1
CDS	39..311
Translation	MSGGGTETPVGCEAAPGGGSKKRDSLGTAGSAHLIIKDLGEIHSRLLDHRPVIQGETRYFVKEFECKQLMTQSVDSNRGNRNEKRFIVTT

Target ORF information:

RefSeq Version	NM_001199323.1
Organism	Homo sapiens(human)
Definition	Homo sapiens biogenesis of lysosomal organelles complex 1 subunit 5 (BLOC1S5), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001199323.1

ORF Insert Sequence:

ATGAGTGGCG GAGGGACAGA GACCCCTGTG GGTTGTGAGG CCGCCCCGGG CGGTGGCAGC 
AAGAAGAGGG ACTCCCTGGG GACTGCGGGC TCAGCGCACC TCATTATCAA GGATCTTGGA 
GAAATTCATT CAAGGCTTTT GGATCACAGA CCAGTTATTC AAGGTGAAAC TCGTTATTTT 
GTAAAAGAAT TTGAATGCAA GCAGCTAATG ACTCAGTCTG TAGACTCCAA CAGAGGGAAC 
AGGAACGAAA AAAGATTCAT AGTGACCACT TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Assembly and architecture of biogenesis of lysosome-related organelles complex-1 (BLOC-1).
The Journal of biological chemistry287(8)5882-90(2012 Feb)
Lee HH,Nemecek D,Schindler C,Smith WJ,Ghirlando R,Steven AC,Bonifacino JS,Hurley JH

An integrative method for scoring candidate genes from association studies: application to warfarin dosing.
BMC bioinformatics11 Suppl 9S9(2010 Oct)
Tatonetti NP,Dudley JT,Sagreiya H,Butte AJ,Altman RB

Dysbindin (DTNBP1) and the biogenesis of lysosome-related organelles complex 1 (BLOC-1): main and epistatic gene effects are potential contributors to schizophrenia susceptibility.
Biological psychiatry63(1)24-31(2008 Jan)
Morris DW,Murphy K,Kenny N,Purcell SM,McGhee KA,Schwaiger S,Nangle JM,Donohoe G,Clarke S,Scully P,Quinn J,Meagher D,Baldwin P,Crumlish N,O'Callaghan E,Waddington JL,Gill M,Corvin AP

BLOC-1 is required for cargo-specific sorting from vacuolar early endosomes toward lysosome-related organelles.
Molecular biology of the cell18(3)768-80(2007 Mar)
Setty SR,Tenza D,Truschel ST,Chou E,Sviderskaya EV,Theos AC,Lamoreux ML,Di Pietro SM,Starcevic M,Bennett DC,Dell'Angelica EC,Raposo G,Marks MS

Transcriptome analysis of human gastric cancer.
Mammalian genome : official journal of the International Mammalian Genome Society16(12)942-54(2005 Dec)
Oh JH,Yang JO,Hahn Y,Kim MR,Byun SS,Jeon YJ,Kim JM,Song KS,Noh SM,Kim S,Yoo HS,Kim YS,Kim NS

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

[email protected]

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

BLOC1S5 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム