RGS2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RGS2
Entrez Gene ID	5997
Full Name	regulator of G protein signaling 2
Synonyms	G0S8
General protein information	Preferred Names regulator of G protein signaling 2 Names regulator of G-protein signaling 2 G0 to G1 switch regulatory 8, 24kD G0/G1 switch regulatory protein 8 cell growth-inhibiting gene 31 protein cell growth-inhibiting protein 31 regulator of G-protein signaling 2, 24kDa
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q31.2
Summary	Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis. [provided by RefSeq, Aug 2009].
Disorder MIM:	600861

mRNA and Protein(s)

mRNA	Protein	Name
NM_002923.3	NP_002914.1	regulator of G-protein signaling 2
NM_002923.4	NP_002914.1	regulator of G-protein signaling 2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	RGS2	XP_005640987.1
Mus musculus (house mouse)	Rgs2	NP_033087.2
	RGS2	XP_001112788.1
Xenopus tropicalis (tropical clawed frog)	rgs2	NP_001025622.1
Pan troglodytes (chimpanzee)	RGS2	XP_001166601.1
Rattus norvegicus (Norway rat)	Rgs2	NP_445905.1
Gallus gallus (chicken)	RGS2	NP_989726.1
Homo sapiens (human)	RGS2	NP_002914.1

Gene Ontology

The following RGS2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RGS2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu28369	NM_002923.4 Latest version!	Homo sapiens regulator of G protein signaling 2 (RGS2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu28369	NM_002923.3	Homo sapiens regulator of G protein signaling 2 (RGS2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RGS2 ( NM_002923.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002914.1 Homo sapiens regulator of G protein signaling 2 (RGS2), mRNA.

Price & Availability↑

CloneID	OHu28369
Clone ID Related Accession (Same CDS sequence)	NM_002923.3 , NM_002923.4
Accession Version	NM_002923.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 636bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-10
Organism	Homo sapiens(human)
Product	regulator of G-protein signaling 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CD700013.1, BC007049.1 and BI912389.1. This sequence is a reference standard in the RefSeqGene project. On Aug 11, 2009 this sequence version replaced NM_002923.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.371209.1, BC007049.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAAAGTG CTATGTTCTT GGCTGTTCAA CACGACTGCA GACCCATGGA CAAGAGCGCA 
GGCAGTGGCC ACAAGAGCGA GGAGAAGCGA GAAAAGATGA AACGGACCCT TTTAAAAGAT 
TGGAAGACCC GTTTGAGCTA CTTCTTACAA AATTCCTCTA CTCCTGGGAA GCCCAAAACC 
GGCAAAAAAA GCAAACAGCA AGCTTTCATC AAGCCTTCTC CTGAGGAAGC ACAGCTGTGG 
TCAGAAGCAT TTGACGAGCT GCTAGCCAGC AAATATGGTC TTGCTGCATT CAGGGCTTTT 
TTAAAGTCGG AATTCTGTGA AGAAAATATT GAATTCTGGC TGGCCTGTGA AGACTTCAAA 
AAAACCAAAT CACCCCAAAA GCTGTCCTCA AAAGCAAGGA AAATATATAC TGACTTCATA 
GAAAAGGAAG CTCCAAAAGA GATAAACATA GATTTTCAAA CCAAAACTCT GATTGCCCAG 
AATATACAAG AAGCTACAAG TGGCTGCTTT ACAACTGCCC AGAAAAGGGT ATACAGCTTG 
ATGGAGAACA ACTCTTATCC TCGTTTCTTG GAGTCAGAAT TCTACCAGGA CTTGTGTAAA 
AAGCCACAAA TCACCACAGA GCCTCATGCT ACATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002914.1
CDS	34..669
Translation	MQSAMFLAVQHDCRPMDKSAGSGHKSEEKREKMKRTLLKDWKTRLSYFLQNSSTPGKPKTGKKSKQQAFIKPSPEEAQLWSEAFDELLASKYGLAAFRAFLKSEFCEENIEFWLACEDFKKTKSPQKLSSKARKIYTDFIEKEAPKEINIDFQTKTLIAQNIQEATSGCFTTAQKRVYSLMENNSYPRFLESEFYQDLCKKPQITTEPHAT

Target ORF information:

RefSeq Version	NM_002923.3
Organism	Homo sapiens(human)
Definition	Homo sapiens regulator of G protein signaling 2 (RGS2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002923.3

ORF Insert Sequence:

ATGCAAAGTG CTATGTTCTT GGCTGTTCAA CACGACTGCA GACCCATGGA CAAGAGCGCA 
GGCAGTGGCC ACAAGAGCGA GGAGAAGCGA GAAAAGATGA AACGGACCCT TTTAAAAGAT 
TGGAAGACCC GTTTGAGCTA CTTCTTACAA AATTCCTCTA CTCCTGGGAA GCCCAAAACC 
GGCAAAAAAA GCAAACAGCA AGCTTTCATC AAGCCTTCTC CTGAGGAAGC ACAGCTGTGG 
TCAGAAGCAT TTGACGAGCT GCTAGCCAGC AAATATGGTC TTGCTGCATT CAGGGCTTTT 
TTAAAGTCGG AATTCTGTGA AGAAAATATT GAATTCTGGC TGGCCTGTGA AGACTTCAAA 
AAAACCAAAT CACCCCAAAA GCTGTCCTCA AAAGCAAGGA AAATATATAC TGACTTCATA 
GAAAAGGAAG CTCCAAAAGA GATAAACATA GATTTTCAAA CCAAAACTCT GATTGCCCAG 
AATATACAAG AAGCTACAAG TGGCTGCTTT ACAACTGCCC AGAAAAGGGT ATACAGCTTG 
ATGGAGAACA ACTCTTATCC TCGTTTCTTG GAGTCAGAAT TCTACCAGGA CTTGTGTAAA 
AAGCCACAAA TCACCACAGA GCCTCATGCT ACATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RGS2 ( NM_002923.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_002914.1 Homo sapiens regulator of G protein signaling 2 (RGS2), mRNA.

Price & Availability↑

CloneID	OHu28369
Clone ID Related Accession (Same CDS sequence)	NM_002923.3 , NM_002923.4
Accession Version	NM_002923.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 636bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-31
Organism	Homo sapiens(human)
Product	regulator of G-protein signaling 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CD700013.1, BC007049.1 and BI912389.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_002923.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.1095256.1, SRR3476690.817888.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000235382.7/ ENSP00000235382.5 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCAAAGTG CTATGTTCTT GGCTGTTCAA CACGACTGCA GACCCATGGA CAAGAGCGCA 
GGCAGTGGCC ACAAGAGCGA GGAGAAGCGA GAAAAGATGA AACGGACCCT TTTAAAAGAT 
TGGAAGACCC GTTTGAGCTA CTTCTTACAA AATTCCTCTA CTCCTGGGAA GCCCAAAACC 
GGCAAAAAAA GCAAACAGCA AGCTTTCATC AAGCCTTCTC CTGAGGAAGC ACAGCTGTGG 
TCAGAAGCAT TTGACGAGCT GCTAGCCAGC AAATATGGTC TTGCTGCATT CAGGGCTTTT 
TTAAAGTCGG AATTCTGTGA AGAAAATATT GAATTCTGGC TGGCCTGTGA AGACTTCAAA 
AAAACCAAAT CACCCCAAAA GCTGTCCTCA AAAGCAAGGA AAATATATAC TGACTTCATA 
GAAAAGGAAG CTCCAAAAGA GATAAACATA GATTTTCAAA CCAAAACTCT GATTGCCCAG 
AATATACAAG AAGCTACAAG TGGCTGCTTT ACAACTGCCC AGAAAAGGGT ATACAGCTTG 
ATGGAGAACA ACTCTTATCC TCGTTTCTTG GAGTCAGAAT TCTACCAGGA CTTGTGTAAA 
AAGCCACAAA TCACCACAGA GCCTCATGCT ACATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002914.1
CDS	34..669
Translation	MQSAMFLAVQHDCRPMDKSAGSGHKSEEKREKMKRTLLKDWKTRLSYFLQNSSTPGKPKTGKKSKQQAFIKPSPEEAQLWSEAFDELLASKYGLAAFRAFLKSEFCEENIEFWLACEDFKKTKSPQKLSSKARKIYTDFIEKEAPKEINIDFQTKTLIAQNIQEATSGCFTTAQKRVYSLMENNSYPRFLESEFYQDLCKKPQITTEPHAT

Target ORF information:

RefSeq Version	NM_002923.4
Organism	Homo sapiens(human)
Definition	Homo sapiens regulator of G protein signaling 2 (RGS2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002923.4

ORF Insert Sequence:

ATGCAAAGTG CTATGTTCTT GGCTGTTCAA CACGACTGCA GACCCATGGA CAAGAGCGCA 
GGCAGTGGCC ACAAGAGCGA GGAGAAGCGA GAAAAGATGA AACGGACCCT TTTAAAAGAT 
TGGAAGACCC GTTTGAGCTA CTTCTTACAA AATTCCTCTA CTCCTGGGAA GCCCAAAACC 
GGCAAAAAAA GCAAACAGCA AGCTTTCATC AAGCCTTCTC CTGAGGAAGC ACAGCTGTGG 
TCAGAAGCAT TTGACGAGCT GCTAGCCAGC AAATATGGTC TTGCTGCATT CAGGGCTTTT 
TTAAAGTCGG AATTCTGTGA AGAAAATATT GAATTCTGGC TGGCCTGTGA AGACTTCAAA 
AAAACCAAAT CACCCCAAAA GCTGTCCTCA AAAGCAAGGA AAATATATAC TGACTTCATA 
GAAAAGGAAG CTCCAAAAGA GATAAACATA GATTTTCAAA CCAAAACTCT GATTGCCCAG 
AATATACAAG AAGCTACAAG TGGCTGCTTT ACAACTGCCC AGAAAAGGGT ATACAGCTTG 
ATGGAGAACA ACTCTTATCC TCGTTTCTTG GAGTCAGAAT TCTACCAGGA CTTGTGTAAA 
AAGCCACAAA TCACCACAGA GCCTCATGCT ACATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.