NPDC1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NPDC1
Entrez Gene ID	56654
Full Name	neural proliferation, differentiation and control 1
Synonyms	CAB,CAB-,CAB-1,CAB1,NPDC-1
General protein information	Preferred Names neural proliferation, differentiation and control 1 Names neural proliferation differentiation and control protein 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 9 Map Location: 9q34.3
Disorder MIM:	605798

mRNA and Protein(s)

mRNA	Protein	Name
NM_015392.3	NP_056207.3	neural proliferation differentiation and control protein 1 precursor
NM_015392.4	NP_056207.3	neural proliferation differentiation and control protein 1 precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	NPDC1	NP_001098959.1
Mus musculus (house mouse)	Npdc1	NP_032747.2
Rattus norvegicus (Norway rat)	Npdc1	NP_001004231.1
Gallus gallus (chicken)	NPDC1	XP_001233959.3
Homo sapiens (human)	NPDC1	NP_056207.3
	NPDC1	XP_001091499.2
Danio rerio (zebrafish)	LOC556607	XP_005172004.1
Canis lupus familiaris (dog)	NPDC1	XP_005625487.1
Xenopus tropicalis (tropical clawed frog)	LOC100497919	XP_002942016.2
Danio rerio (zebrafish)	npdc1a	NP_001122255.1

Gene Ontology
Bibliography

Related articles in PubMed

Functional analysis of the NPDC-1 gene.
Evrard C, Caron S, Rouget P
Gene343(1)153-63(2004 Dec)

NPDC-1, a novel regulator of neuronal proliferation, is degraded by the ubiquitin/proteasome system through a PEST degradation motif.
Spencer ML, Theodosiou M, Noonan DJ
The Journal of biological chemistry279(35)37069-78(2004 Aug)

Characterization and tissue expression of a novel human gene npdc1.
Qu X, Zhang C, Zhai Y, Xing G, Wei H, Yu Y, Wu S, He F
Gene264(1)37-44(2001 Feb)

NPDC-1, a regulator of neural cell proliferation and differentiation, interacts with E2F-1, reduces its binding to DNA and modulates its transcriptional activity.
Sansal I, Dupont E, Toru D, Evrard C, Rouget P
Oncogene19(43)5000-9(2000 Oct)

The Rab3 GDP/GTP exchange factor homolog AEX-3 has a dual function in synaptic transmission.
Iwasaki K, Toyonaga R
The EMBO journal19(17)4806-16(2000 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Human gene mapped to chromosome 9q34.3.
Title: Functional analysis of the NPDC-1 gene.

NPDC-1 has a role in regulating neuronal proliferation and is degraded by the ubiquitin/proteasome system through a PEST degradation motif
Title: NPDC-1, a novel regulator of neuronal proliferation, is degraded by the ubiquitin/proteasome system through a PEST degradation motif.

The following NPDC1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NPDC1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu10509	NM_015392.4 Latest version!	Homo sapiens neural proliferation, differentiation and control 1 (NPDC1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
View Old Accession Versions >>
OHu10509	NM_015392.3	Homo sapiens neural proliferation, differentiation and control 1 (NPDC1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NPDC1 ( NM_015392.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_056207.3 Homo sapiens neural proliferation, differentiation and control 1 (NPDC1), mRNA.

Price & Availability↑

CloneID	OHu10509
Clone ID Related Accession (Same CDS sequence)	NM_015392.3 , NM_015392.4
Accession Version	NM_015392.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 978bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	neural proliferation differentiation and control protein 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL807752.10 and BC004217.2. On Feb 10, 2009 this sequence version replaced NM_015392.2. ##Evidence-Data-START## Transcript exon combination :: BC004217.2, AF285836.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGACGC CGCTGCCTCC GCCCTCCCCG CGGCACCTGC GGCTGCTGCG GCTGCTGCTC 
TCCGGCCTCG TCCTCGGCGC CGCCCTGCGT GGAGCCGCCG CCGGCCACCC GGATGTAGCC 
GCCTGTCCCG GGAGCCTGGA CTGTGCCCTG AAGAGGCGGG CAAGGTGTCC TCCTGGTGCA 
CATGCCTGTG GGCCCTGCCT TCAGCCCTTC CAGGAGGACC AGCAAGGGCT CTGTGTGCCC 
AGGATGCGCC GGCCTCCAGG CGGGGGCCGG CCCCAGCCCA GACTGGAAGA TGAGATTGAC 
TTCCTGGCCC AGGAGCTTGC CCGGAAGGAG TCTGGACACT CAACTCCGCC CCTACCCAAG 
GACCGACAGC GGCTCCCGGA GCCTGCCACC CTGGGCTTCT CGGCACGGGG GCAGGGGCTG 
GAGCTGGGCC TCCCCTCCAC TCCAGGAACC CCCACGCCCA CGCCCCACAC CTCCCTGGGC 
TCCCCTGTGT CATCCGACCC GGTGCACATG TCGCCCCTGG AGCCCCGGGG AGGGCAAGGC 
GACGGCCTCG CCCTTGTGCT GATCCTGGCG TTCTGTGTGG CCGGTGCAGC CGCCCTCTCC 
GTAGCCTCCC TCTGCTGGTG CAGGCTGCAG CGTGAGATCC GCCTGACTCA GAAGGCCGAC 
TACGCCACTG CGAAGGCCCC TGGCTCACCT GCAGCTCCCC GGATCTCGCC TGGGGACCAG 
CGGCTGGCAC AGAGCGCGGA GATGTACCAC TACCAGCACC AACGGCAACA GATGCTGTGC 
CTGGAGCGGC ATAAAGAGCC ACCCAAGGAG CTGGACACGG CCTCCTCGGA TGAGGAGAAT 
GAGGACGGAG ACTTCACGGT GTACGAGTGC CCGGGCCTGG CCCCGACCGG GGAAATGGAG 
GTGCGCAACC CTCTGTTCGA CCACGCCGCA CTGTCCGCGC CCCTGCCGGC CCCCAGCTCA 
CCGCCTGCAC TGCCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056207.3
CDS	236..1213
Translation	MATPLPPPSPRHLRLLRLLLSGLVLGAALRGAAAGHPDVAACPGSLDCALKRRARCPPGAHACGPCLQPFQEDQQGLCVPRMRRPPGGGRPQPRLEDEIDFLAQELARKESGHSTPPLPKDRQRLPEPATLGFSARGQGLELGLPSTPGTPTPTPHTSLGSPVSSDPVHMSPLEPRGGQGDGLALVLILAFCVAGAAALSVASLCWCRLQREIRLTQKADYATAKAPGSPAAPRISPGDQRLAQSAEMYHYQHQRQQMLCLERHKEPPKELDTASSDEENEDGDFTVYECPGLAPTGEMEVRNPLFDHAALSAPLPAPSSPPALP

Target ORF information:

RefSeq Version	NM_015392.3
Organism	Homo sapiens(human)
Definition	Homo sapiens neural proliferation, differentiation and control 1 (NPDC1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015392.3

ORF Insert Sequence:

ATGGCGACGC CGCTGCCTCC GCCCTCCCCG CGGCACCTGC GGCTGCTGCG GCTGCTGCTC 
TCCGGCCTCG TCCTCGGCGC CGCCCTGCGT GGAGCCGCCG CCGGCCACCC GGATGTAGCC 
GCCTGTCCCG GGAGCCTGGA CTGTGCCCTG AAGAGGCGGG CAAGGTGTCC TCCTGGTGCA 
CATGCCTGTG GGCCCTGCCT TCAGCCCTTC CAGGAGGACC AGCAAGGGCT CTGTGTGCCC 
AGGATGCGCC GGCCTCCAGG CGGGGGCCGG CCCCAGCCCA GACTGGAAGA TGAGATTGAC 
TTCCTGGCCC AGGAGCTTGC CCGGAAGGAG TCTGGACACT CAACTCCGCC CCTACCCAAG 
GACCGACAGC GGCTCCCGGA GCCTGCCACC CTGGGCTTCT CGGCACGGGG GCAGGGGCTG 
GAGCTGGGCC TCCCCTCCAC TCCAGGAACC CCCACGCCCA CGCCCCACAC CTCCCTGGGC 
TCCCCTGTGT CATCCGACCC GGTGCACATG TCGCCCCTGG AGCCCCGGGG AGGGCAAGGC 
GACGGCCTCG CCCTTGTGCT GATCCTGGCG TTCTGTGTGG CCGGTGCAGC CGCCCTCTCC 
GTAGCCTCCC TCTGCTGGTG CAGGCTGCAG CGTGAGATCC GCCTGACTCA GAAGGCCGAC 
TACGCCACTG CGAAGGCCCC TGGCTCACCT GCAGCTCCCC GGATCTCGCC TGGGGACCAG 
CGGCTGGCAC AGAGCGCGGA GATGTACCAC TACCAGCACC AACGGCAACA GATGCTGTGC 
CTGGAGCGGC ATAAAGAGCC ACCCAAGGAG CTGGACACGG CCTCCTCGGA TGAGGAGAAT 
GAGGACGGAG ACTTCACGGT GTACGAGTGC CCGGGCCTGG CCCCGACCGG GGAAATGGAG 
GTGCGCAACC CTCTGTTCGA CCACGCCGCA CTGTCCGCGC CCCTGCCGGC CCCCAGCTCA 
CCGCCTGCAC TGCCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NPDC1 ( NM_015392.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_056207.3 Homo sapiens neural proliferation, differentiation and control 1 (NPDC1), mRNA.

Price & Availability↑

CloneID	OHu10509
Clone ID Related Accession (Same CDS sequence)	NM_015392.3 , NM_015392.4
Accession Version	NM_015392.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 978bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	neural proliferation differentiation and control protein 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL807752.10 and BC004217.2. On Nov 23, 2018 this sequence version replaced NM_015392.3. ##Evidence-Data-START## Transcript exon combination :: AK074793.1, SRR3476690.813417.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000371601.5/ ENSP00000360660.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGACGC CGCTGCCTCC GCCCTCCCCG CGGCACCTGC GGCTGCTGCG GCTGCTGCTC 
TCCGGCCTCG TCCTCGGCGC CGCCCTGCGT GGAGCCGCCG CCGGCCACCC GGATGTAGCC 
GCCTGTCCCG GGAGCCTGGA CTGTGCCCTG AAGAGGCGGG CAAGGTGTCC TCCTGGTGCA 
CATGCCTGTG GGCCCTGCCT TCAGCCCTTC CAGGAGGACC AGCAAGGGCT CTGTGTGCCC 
AGGATGCGCC GGCCTCCAGG CGGGGGCCGG CCCCAGCCCA GACTGGAAGA TGAGATTGAC 
TTCCTGGCCC AGGAGCTTGC CCGGAAGGAG TCTGGACACT CAACTCCGCC CCTACCCAAG 
GACCGACAGC GGCTCCCGGA GCCTGCCACC CTGGGCTTCT CGGCACGGGG GCAGGGGCTG 
GAGCTGGGCC TCCCCTCCAC TCCAGGAACC CCCACGCCCA CGCCCCACAC CTCCCTGGGC 
TCCCCTGTGT CATCCGACCC GGTGCACATG TCGCCCCTGG AGCCCCGGGG AGGGCAAGGC 
GACGGCCTCG CCCTTGTGCT GATCCTGGCG TTCTGTGTGG CCGGTGCAGC CGCCCTCTCC 
GTAGCCTCCC TCTGCTGGTG CAGGCTGCAG CGTGAGATCC GCCTGACTCA GAAGGCCGAC 
TACGCCACTG CGAAGGCCCC TGGCTCACCT GCAGCTCCCC GGATCTCGCC TGGGGACCAG 
CGGCTGGCAC AGAGCGCGGA GATGTACCAC TACCAGCACC AACGGCAACA GATGCTGTGC 
CTGGAGCGGC ATAAAGAGCC ACCCAAGGAG CTGGACACGG CCTCCTCGGA TGAGGAGAAT 
GAGGACGGAG ACTTCACGGT GTACGAGTGC CCGGGCCTGG CCCCGACCGG GGAAATGGAG 
GTGCGCAACC CTCTGTTCGA CCACGCCGCA CTGTCCGCGC CCCTGCCGGC CCCCAGCTCA 
CCGCCTGCAC TGCCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056207.3
CDS	189..1166
Translation	MATPLPPPSPRHLRLLRLLLSGLVLGAALRGAAAGHPDVAACPGSLDCALKRRARCPPGAHACGPCLQPFQEDQQGLCVPRMRRPPGGGRPQPRLEDEIDFLAQELARKESGHSTPPLPKDRQRLPEPATLGFSARGQGLELGLPSTPGTPTPTPHTSLGSPVSSDPVHMSPLEPRGGQGDGLALVLILAFCVAGAAALSVASLCWCRLQREIRLTQKADYATAKAPGSPAAPRISPGDQRLAQSAEMYHYQHQRQQMLCLERHKEPPKELDTASSDEENEDGDFTVYECPGLAPTGEMEVRNPLFDHAALSAPLPAPSSPPALP

Target ORF information:

RefSeq Version	NM_015392.4
Organism	Homo sapiens(human)
Definition	Homo sapiens neural proliferation, differentiation and control 1 (NPDC1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015392.4

ORF Insert Sequence:

ATGGCGACGC CGCTGCCTCC GCCCTCCCCG CGGCACCTGC GGCTGCTGCG GCTGCTGCTC 
TCCGGCCTCG TCCTCGGCGC CGCCCTGCGT GGAGCCGCCG CCGGCCACCC GGATGTAGCC 
GCCTGTCCCG GGAGCCTGGA CTGTGCCCTG AAGAGGCGGG CAAGGTGTCC TCCTGGTGCA 
CATGCCTGTG GGCCCTGCCT TCAGCCCTTC CAGGAGGACC AGCAAGGGCT CTGTGTGCCC 
AGGATGCGCC GGCCTCCAGG CGGGGGCCGG CCCCAGCCCA GACTGGAAGA TGAGATTGAC 
TTCCTGGCCC AGGAGCTTGC CCGGAAGGAG TCTGGACACT CAACTCCGCC CCTACCCAAG 
GACCGACAGC GGCTCCCGGA GCCTGCCACC CTGGGCTTCT CGGCACGGGG GCAGGGGCTG 
GAGCTGGGCC TCCCCTCCAC TCCAGGAACC CCCACGCCCA CGCCCCACAC CTCCCTGGGC 
TCCCCTGTGT CATCCGACCC GGTGCACATG TCGCCCCTGG AGCCCCGGGG AGGGCAAGGC 
GACGGCCTCG CCCTTGTGCT GATCCTGGCG TTCTGTGTGG CCGGTGCAGC CGCCCTCTCC 
GTAGCCTCCC TCTGCTGGTG CAGGCTGCAG CGTGAGATCC GCCTGACTCA GAAGGCCGAC 
TACGCCACTG CGAAGGCCCC TGGCTCACCT GCAGCTCCCC GGATCTCGCC TGGGGACCAG 
CGGCTGGCAC AGAGCGCGGA GATGTACCAC TACCAGCACC AACGGCAACA GATGCTGTGC 
CTGGAGCGGC ATAAAGAGCC ACCCAAGGAG CTGGACACGG CCTCCTCGGA TGAGGAGAAT 
GAGGACGGAG ACTTCACGGT GTACGAGTGC CCGGGCCTGG CCCCGACCGG GGAAATGGAG 
GTGCGCAACC CTCTGTTCGA CCACGCCGCA CTGTCCGCGC CCCTGCCGGC CCCCAGCTCA 
CCGCCTGCAC TGCCATGA