ERO1B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ERO1B
Entrez Gene ID	56605
Full Name	endoplasmic reticulum oxidoreductase 1 beta
Synonyms	ERO1LB,Ero1beta
General protein information	Preferred Names endoplasmic reticulum oxidoreductase 1 beta Names ERO1-like protein beta ERO1-L-beta ERO1-like beta endoplasmic oxidoreductin-1-like protein B endoplasmic reticulum oxidoreductase beta endoplasmic reticulum oxidoreductin-1-like protein B oxidoreductin-1-L-beta
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q42.3
Disorder MIM:	615437

mRNA and Protein(s)

mRNA	Protein	Name
XM_024448449.1	XP_024304217.1	ERO1-like protein beta isoform X1
NM_019891.3	NP_063944.3	ERO1-like protein beta precursor
NM_019891.4	NP_063944.3	ERO1-like protein beta precursor
XM_017001834.1	XP_016857323.1	ERO1-like protein beta isoform X2

Pathways from BioSystems

Homologies

Caenorhabditis elegans (roundworm)	ero-1	NP_001021704.1
Homo sapiens (human)	ERO1LB	NP_063944.3
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002816	XP_312095.5
Xenopus tropicalis (tropical clawed frog)	ero1l	NP_001090843.1
Mus musculus (house mouse)	Ero1lb	NP_080460.2
Gallus gallus (chicken)	ERO1LB	XP_419554.3
Drosophila melanogaster (fruit fly)	Ero1L	NP_647865.2
Canis lupus familiaris (dog)	ERO1LB	XP_546074.3
Rattus norvegicus (Norway rat)	Ero1lb	NP_001178822.1
Danio rerio (zebrafish)	ero1lb	NP_001070106.1
Pan troglodytes (chimpanzee)	ERO1LB	XP_001156276.1
Bos taurus (cattle)	ERO1LB	NP_001193659.1

Gene Ontology
Bibliography

Related articles in PubMed

Genome-scale analysis identifies GJB2 and ERO1LB as prognosis markers in patients with pancreatic cancer.
Zhu T, Gao YF, Chen YX, Wang ZB, Yin JY, Mao XY, Li X, Zhang W, Zhou HH, Liu ZQ
Oncotarget8(13)21281-21289(2017 Mar)

The Immunohistochemical Evaluation of Solid Pseudopapillary Tumors of the Pancreas and Pancreatic Neuroendocrine Tumors Reveals ERO1L? as a New Biomarker.
Xie J, Zhu Y, Chen H, Shi M, Gu J, Zhang J, Shen B, Deng X, Zhan X, Peng C
Medicine95(2)e2509(2016 Jan)

Biochemical evidence that regulation of Ero1? activity in human cells does not involve the isoform-specific cysteine 262.
Hansen HG, S?ltoft CL, Schmidt JD, Birk J, Appenzeller-Herzog C, Ellgaard L
Bioscience reports34(2)(2014 Apr)

The endoplasmic reticulum sulfhydryl oxidase Ero1? drives efficient oxidative protein folding with loose regulation.
Wang L, Zhu L, Wang CC
The Biochemical journal434(1)113-21(2011 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

GJB2 and ERO1LB are implicated in pancreatic cancer progression and can be used to predict patient survival
Title: Genome-scale analysis identifies GJB2 and ERO1LB as prognosis markers in patients with pancreatic cancer.

upregulated in pancreatic neuroendocrine tumors
Title: The Immunohistochemical Evaluation of Solid Pseudopapillary Tumors of the Pancreas and Pancreatic Neuroendocrine Tumors Reveals ERO1L? as a New Biomarker.

This peptide, Ac-VDTTD-AFC, was efficiently cleaved by purified caspase-2 and auto-activating caspase-2 in mammalian cells, and exhibited better selectivity for caspase-2 relative to caspase-3 than reagents that are currently available.
Title: Biochemical evidence that regulation of Ero1? activity in human cells does not involve the isoform-specific cysteine 262.

In the present work, it was shown that recombinant human Ero1beta is twice as active as Ero1alpha in enzymatic assays.
Title: The endoplasmic reticulum sulfhydryl oxidase Ero1? drives efficient oxidative protein folding with loose regulation.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

The following ERO1B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ERO1B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu08837	NM_019891.4 Latest version!	Homo sapiens endoplasmic reticulum oxidoreductase 1 beta (ERO1B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
OHu105113	XM_024448449.1 Latest version!	Homo sapiens endoplasmic reticulum oxidoreductase 1 beta (ERO1B), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu90272	XM_017001834.1 Latest version!	Homo sapiens endoplasmic reticulum oxidoreductase 1 beta (ERO1B), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OHu08837	NM_019891.3	Homo sapiens endoplasmic reticulum oxidoreductase 1 beta (ERO1B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ERO1B ( NM_019891.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_063944.3 Homo sapiens endoplasmic reticulum oxidoreductase 1 beta (ERO1B), mRNA.

Price & Availability↑

CloneID	OHu08837
Clone ID Related Accession (Same CDS sequence)	NM_019891.3 , NM_019891.4
Accession Version	NM_019891.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1404bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	ERO1-like protein beta precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL450309.14, BG723126.1, BC044573.1, AL139162.20 and CR749523.1. On Jun 9, 2009 this sequence version replaced NM_019891.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.247878.1, SRR1803613.151789.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCCAAG GGGTCCGCCG GGCAGGCGCT GGGCAGGGGG TAGCGGCCGC GGTGCAGCTG 
CTGGTCACCC TGAGCTTCCT GCGGAGCGTC GTCGAGGCGC AGGTCACTGG AGTTCTGGAT 
GATTGCTTGT GTGATATTGA CAGCATCGAT AACTTCAATA CCTACAAAAT CTTCCCCAAA 
ATAAAAAAAT TGCAAGAGAG AGACTATTTT CGTTATTACA AGGTTAATCT GAAGCGACCT 
TGTCCTTTCT GGGCAGAAGA TGGCCACTGT TCAATAAAAG ACTGTCATGT GGAGCCCTGT 
CCAGAGAGTA AAATTCCGGT TGGAATAAAA GCTGGGCATT CTAATAAGTA CTTGAAAATG 
GCAAACAATA CCAAAGAATT AGAAGATTGT GAGCAAGCTA ATAAACTGGG AGCAATTAAC 
AGCACATTAA GTAATCAAAG CAAAGAAGCT TTCATTGACT GGGCAAGATA TGATGATTCA 
CGGGATCACT TTTGTGAACT TGATGATGAG AGATCTCCAG CTGCTCAGTA TGTAGACCTA 
TTGCTGAACC CAGAGCGTTA CACTGGCTAT AAAGGGACCT CTGCATGGAG AGTGTGGAAC 
AGCATCTATG AAGAGAACTG TTTCAAGCCT CGATCTGTTT ATCGTCCTTT AAATCCTCTG 
GCGCCTAGCC GAGGCGAAGA TGATGGAGAA TCATTCTACA CATGGCTAGA AGGTTTGTGT 
CTGGAGAAAA GAGTCTTCTA TAAGCTTATA TCGGGACTTC ATGCTAGCAT CAATTTACAT 
CTATGCGCAA ATTATCTTTT GGAAGAAACC TGGGGTAAGC CCAGTTGGGG ACCTAATATT 
AAAGAATTCA AACACCGCTT TGACCCTGTG GAAACCAAGG GAGAAGGTCC AAGAAGGCTC 
AAGAATCTTT ACTTTTTATA CTTGATTGAG CTTCGAGCTT TGTCAAAGGT GGCTCCATAT 
TTTGAGCGCT CAATTGTCGA TCTTTACACT GGAAATGCAG AAGAAGATGC TGACACAAAA 
ACTCTTCTAC TGAATATCTT TCAAGATACA AAGTCCTTTC CCATGCACTT TGATGAGAAA 
TCCATGTTTG CAGGTGACAA AAAAGGGGCC AAGTCACTAA AGGAGGAATT CCGATTACAT 
TTCAAGAATA TCTCCCGTAT AATGGACTGT GTTGGATGTG ACAAATGCAG ATTATGGGGA 
AAATTACAGA CTCAGGGTTT AGGAACTGCC CTGAAGATAT TATTCTCTGA AAAAGAAATC 
CAAAAGCTTC CAGAGAATAG TCCATCTAAA GGCTTCCAAC TCACCCGACA GGAAATAGTT 
GCTCTTTTAA ATGCTTTTGG AAGGCTTTCT ACAAGTATAA GAGACTTACA GAATTTTAAA 
GTCTTATTAC AACACAGTAG GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_063944.3
CDS	257..1660
Translation	MSQGVRRAGAGQGVAAAVQLLVTLSFLRSVVEAQVTGVLDDCLCDIDSIDNFNTYKIFPKIKKLQERDYFRYYKVNLKRPCPFWAEDGHCSIKDCHVEPCPESKIPVGIKAGHSNKYLKMANNTKELEDCEQANKLGAINSTLSNQSKEAFIDWARYDDSRDHFCELDDERSPAAQYVDLLLNPERYTGYKGTSAWRVWNSIYEENCFKPRSVYRPLNPLAPSRGEDDGESFYTWLEGLCLEKRVFYKLISGLHASINLHLCANYLLEETWGKPSWGPNIKEFKHRFDPVETKGEGPRRLKNLYFLYLIELRALSKVAPYFERSIVDLYTGNAEEDADTKTLLLNIFQDTKSFPMHFDEKSMFAGDKKGAKSLKEEFRLHFKNISRIMDCVGCDKCRLWGKLQTQGLGTALKILFSEKEIQKLPENSPSKGFQLTRQEIVALLNAFGRLSTSIRDLQNFKVLLQHSR

Target ORF information:

RefSeq Version	NM_019891.3
Organism	Homo sapiens(human)
Definition	Homo sapiens endoplasmic reticulum oxidoreductase 1 beta (ERO1B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019891.3

ORF Insert Sequence:

ATGAGCCAAG GGGTCCGCCG GGCAGGCGCT GGGCAGGGGG TAGCGGCCGC GGTGCAGCTG 
CTGGTCACCC TGAGCTTCCT GCGGAGCGTC GTCGAGGCGC AGGTCACTGG AGTTCTGGAT 
GATTGCTTGT GTGATATTGA CAGCATCGAT AACTTCAATA CCTACAAAAT CTTCCCCAAA 
ATAAAAAAAT TGCAAGAGAG AGACTATTTT CGTTATTACA AGGTTAATCT GAAGCGACCT 
TGTCCTTTCT GGGCAGAAGA TGGCCACTGT TCAATAAAAG ACTGTCATGT GGAGCCCTGT 
CCAGAGAGTA AAATTCCGGT TGGAATAAAA GCTGGGCATT CTAATAAGTA CTTGAAAATG 
GCAAACAATA CCAAAGAATT AGAAGATTGT GAGCAAGCTA ATAAACTGGG AGCAATTAAC 
AGCACATTAA GTAATCAAAG CAAAGAAGCT TTCATTGACT GGGCAAGATA TGATGATTCA 
CGGGATCACT TTTGTGAACT TGATGATGAG AGATCTCCAG CTGCTCAGTA TGTAGACCTA 
TTGCTGAACC CAGAGCGTTA CACTGGCTAT AAAGGGACCT CTGCATGGAG AGTGTGGAAC 
AGCATCTATG AAGAGAACTG TTTCAAGCCT CGATCTGTTT ATCGTCCTTT AAATCCTCTG 
GCGCCTAGCC GAGGCGAAGA TGATGGAGAA TCATTCTACA CATGGCTAGA AGGTTTGTGT 
CTGGAGAAAA GAGTCTTCTA TAAGCTTATA TCGGGACTTC ATGCTAGCAT CAATTTACAT 
CTATGCGCAA ATTATCTTTT GGAAGAAACC TGGGGTAAGC CCAGTTGGGG ACCTAATATT 
AAAGAATTCA AACACCGCTT TGACCCTGTG GAAACCAAGG GAGAAGGTCC AAGAAGGCTC 
AAGAATCTTT ACTTTTTATA CTTGATTGAG CTTCGAGCTT TGTCAAAGGT GGCTCCATAT 
TTTGAGCGCT CAATTGTCGA TCTTTACACT GGAAATGCAG AAGAAGATGC TGACACAAAA 
ACTCTTCTAC TGAATATCTT TCAAGATACA AAGTCCTTTC CCATGCACTT TGATGAGAAA 
TCCATGTTTG CAGGTGACAA AAAAGGGGCC AAGTCACTAA AGGAGGAATT CCGATTACAT 
TTCAAGAATA TCTCCCGTAT AATGGACTGT GTTGGATGTG ACAAATGCAG ATTATGGGGA 
AAATTACAGA CTCAGGGTTT AGGAACTGCC CTGAAGATAT TATTCTCTGA AAAAGAAATC 
CAAAAGCTTC CAGAGAATAG TCCATCTAAA GGCTTCCAAC TCACCCGACA GGAAATAGTT 
GCTCTTTTAA ATGCTTTTGG AAGGCTTTCT ACAAGTATAA GAGACTTACA GAATTTTAAA 
GTCTTATTAC AACACAGTAG GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ERO1B ( NM_019891.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_063944.3 Homo sapiens endoplasmic reticulum oxidoreductase 1 beta (ERO1B), mRNA.

Price & Availability↑

CloneID	OHu08837
Clone ID Related Accession (Same CDS sequence)	NM_019891.3 , NM_019891.4
Accession Version	NM_019891.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1404bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	ERO1-like protein beta precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BG723126.1, AL450309.14, BC044573.1, AL139162.20 and CR749523.1. On May 17, 2019 this sequence version replaced NM_019891.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.277093.1, SRR1660805.78358.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000354619.10/ ENSP00000346635.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGCCAAG GGGTCCGCCG GGCAGGCGCT GGGCAGGGGG TAGCGGCCGC GGTGCAGCTG 
CTGGTCACCC TGAGCTTCCT GCGGAGCGTC GTCGAGGCGC AGGTCACTGG AGTTCTGGAT 
GATTGCTTGT GTGATATTGA CAGCATCGAT AACTTCAATA CCTACAAAAT CTTCCCCAAA 
ATAAAAAAAT TGCAAGAGAG AGACTATTTT CGTTATTACA AGGTTAATCT GAAGCGACCT 
TGTCCTTTCT GGGCAGAAGA TGGCCACTGT TCAATAAAAG ACTGTCATGT GGAGCCCTGT 
CCAGAGAGTA AAATTCCGGT TGGAATAAAA GCTGGGCATT CTAATAAGTA CTTGAAAATG 
GCAAACAATA CCAAAGAATT AGAAGATTGT GAGCAAGCTA ATAAACTGGG AGCAATTAAC 
AGCACATTAA GTAATCAAAG CAAAGAAGCT TTCATTGACT GGGCAAGATA TGATGATTCA 
CGGGATCACT TTTGTGAACT TGATGATGAG AGATCTCCAG CTGCTCAGTA TGTAGACCTA 
TTGCTGAACC CAGAGCGTTA CACTGGCTAT AAAGGGACCT CTGCATGGAG AGTGTGGAAC 
AGCATCTATG AAGAGAACTG TTTCAAGCCT CGATCTGTTT ATCGTCCTTT AAATCCTCTG 
GCGCCTAGCC GAGGCGAAGA TGATGGAGAA TCATTCTACA CATGGCTAGA AGGTTTGTGT 
CTGGAGAAAA GAGTCTTCTA TAAGCTTATA TCGGGACTTC ATGCTAGCAT CAATTTACAT 
CTATGCGCAA ATTATCTTTT GGAAGAAACC TGGGGTAAGC CCAGTTGGGG ACCTAATATT 
AAAGAATTCA AACACCGCTT TGACCCTGTG GAAACCAAGG GAGAAGGTCC AAGAAGGCTC 
AAGAATCTTT ACTTTTTATA CTTGATTGAG CTTCGAGCTT TGTCAAAGGT GGCTCCATAT 
TTTGAGCGCT CAATTGTCGA TCTTTACACT GGAAATGCAG AAGAAGATGC TGACACAAAA 
ACTCTTCTAC TGAATATCTT TCAAGATACA AAGTCCTTTC CCATGCACTT TGATGAGAAA 
TCCATGTTTG CAGGTGACAA AAAAGGGGCC AAGTCACTAA AGGAGGAATT CCGATTACAT 
TTCAAGAATA TCTCCCGTAT AATGGACTGT GTTGGATGTG ACAAATGCAG ATTATGGGGA 
AAATTACAGA CTCAGGGTTT AGGAACTGCC CTGAAGATAT TATTCTCTGA AAAAGAAATC 
CAAAAGCTTC CAGAGAATAG TCCATCTAAA GGCTTCCAAC TCACCCGACA GGAAATAGTT 
GCTCTTTTAA ATGCTTTTGG AAGGCTTTCT ACAAGTATAA GAGACTTACA GAATTTTAAA 
GTCTTATTAC AACACAGTAG GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_063944.3
CDS	176..1579
Translation	MSQGVRRAGAGQGVAAAVQLLVTLSFLRSVVEAQVTGVLDDCLCDIDSIDNFNTYKIFPKIKKLQERDYFRYYKVNLKRPCPFWAEDGHCSIKDCHVEPCPESKIPVGIKAGHSNKYLKMANNTKELEDCEQANKLGAINSTLSNQSKEAFIDWARYDDSRDHFCELDDERSPAAQYVDLLLNPERYTGYKGTSAWRVWNSIYEENCFKPRSVYRPLNPLAPSRGEDDGESFYTWLEGLCLEKRVFYKLISGLHASINLHLCANYLLEETWGKPSWGPNIKEFKHRFDPVETKGEGPRRLKNLYFLYLIELRALSKVAPYFERSIVDLYTGNAEEDADTKTLLLNIFQDTKSFPMHFDEKSMFAGDKKGAKSLKEEFRLHFKNISRIMDCVGCDKCRLWGKLQTQGLGTALKILFSEKEIQKLPENSPSKGFQLTRQEIVALLNAFGRLSTSIRDLQNFKVLLQHSR

Target ORF information:

RefSeq Version	NM_019891.4
Organism	Homo sapiens(human)
Definition	Homo sapiens endoplasmic reticulum oxidoreductase 1 beta (ERO1B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019891.4

ORF Insert Sequence:

ATGAGCCAAG GGGTCCGCCG GGCAGGCGCT GGGCAGGGGG TAGCGGCCGC GGTGCAGCTG 
CTGGTCACCC TGAGCTTCCT GCGGAGCGTC GTCGAGGCGC AGGTCACTGG AGTTCTGGAT 
GATTGCTTGT GTGATATTGA CAGCATCGAT AACTTCAATA CCTACAAAAT CTTCCCCAAA 
ATAAAAAAAT TGCAAGAGAG AGACTATTTT CGTTATTACA AGGTTAATCT GAAGCGACCT 
TGTCCTTTCT GGGCAGAAGA TGGCCACTGT TCAATAAAAG ACTGTCATGT GGAGCCCTGT 
CCAGAGAGTA AAATTCCGGT TGGAATAAAA GCTGGGCATT CTAATAAGTA CTTGAAAATG 
GCAAACAATA CCAAAGAATT AGAAGATTGT GAGCAAGCTA ATAAACTGGG AGCAATTAAC 
AGCACATTAA GTAATCAAAG CAAAGAAGCT TTCATTGACT GGGCAAGATA TGATGATTCA 
CGGGATCACT TTTGTGAACT TGATGATGAG AGATCTCCAG CTGCTCAGTA TGTAGACCTA 
TTGCTGAACC CAGAGCGTTA CACTGGCTAT AAAGGGACCT CTGCATGGAG AGTGTGGAAC 
AGCATCTATG AAGAGAACTG TTTCAAGCCT CGATCTGTTT ATCGTCCTTT AAATCCTCTG 
GCGCCTAGCC GAGGCGAAGA TGATGGAGAA TCATTCTACA CATGGCTAGA AGGTTTGTGT 
CTGGAGAAAA GAGTCTTCTA TAAGCTTATA TCGGGACTTC ATGCTAGCAT CAATTTACAT 
CTATGCGCAA ATTATCTTTT GGAAGAAACC TGGGGTAAGC CCAGTTGGGG ACCTAATATT 
AAAGAATTCA AACACCGCTT TGACCCTGTG GAAACCAAGG GAGAAGGTCC AAGAAGGCTC 
AAGAATCTTT ACTTTTTATA CTTGATTGAG CTTCGAGCTT TGTCAAAGGT GGCTCCATAT 
TTTGAGCGCT CAATTGTCGA TCTTTACACT GGAAATGCAG AAGAAGATGC TGACACAAAA 
ACTCTTCTAC TGAATATCTT TCAAGATACA AAGTCCTTTC CCATGCACTT TGATGAGAAA 
TCCATGTTTG CAGGTGACAA AAAAGGGGCC AAGTCACTAA AGGAGGAATT CCGATTACAT 
TTCAAGAATA TCTCCCGTAT AATGGACTGT GTTGGATGTG ACAAATGCAG ATTATGGGGA 
AAATTACAGA CTCAGGGTTT AGGAACTGCC CTGAAGATAT TATTCTCTGA AAAAGAAATC 
CAAAAGCTTC CAGAGAATAG TCCATCTAAA GGCTTCCAAC TCACCCGACA GGAAATAGTT 
GCTCTTTTAA ATGCTTTTGG AAGGCTTTCT ACAAGTATAA GAGACTTACA GAATTTTAAA 
GTCTTATTAC AACACAGTAG GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ERO1B ( XM_024448449.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024304217.1 Homo sapiens endoplasmic reticulum oxidoreductase 1 beta (ERO1B), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu105113
Clone ID Related Accession (Same CDS sequence)	XM_024448449.1
Accession Version	XM_024448449.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 807bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	ERO1-like protein beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTTGGGT ATTATGCTTT CTTTTTCAGG CCTCGATCTG TTTATCGTCC TTTAAATCCT 
CTGGCGCCTA GCCGAGGCGA AGATGATGGA GAATCATTCT ACACATGGCT AGAAGGTTTG 
TGTCTGGAGA AAAGAGTCTT CTATAAGCTT ATATCGGGAC TTCATGCTAG CATCAATTTA 
CATCTATGCG CAAATTATCT TTTGGAAGAA ACCTGGGGTA AGCCCAGTTG GGGACCTAAT 
ATTAAAGAAT TCAAACACCG CTTTGACCCT GTGGAAACCA AGGGAGAAGG TCCAAGAAGG 
CTCAAGAATC TTTACTTTTT ATACTTGATT GAGCTTCGAG CTTTGTCAAA GGTGGCTCCA 
TATTTTGAGC GCTCAATTGT CGATCTTTAC ACTGGAAATG CAGAAGAAGA TGCTGACACA 
AAAACTCTTC TACTGAATAT CTTTCAAGAT ACAAAGTCCT TTCCCATGCA CTTTGATGAG 
AAATCCATGT TTGCAGGTGA CAAAAAAGGG GCCAAGTCAC TAAAGGAGGA ATTCCGATTA 
CATTTCAAGA ATATCTCCCG TATAATGGAC TGTGTTGGAT GTGACAAATG CAGATTATGG 
GGAAAATTAC AGACTCAGGG TTTAGGAACT GCCCTGAAGA TATTATTCTC TGAAAAAGAA 
ATCCAAAAGC TTCCAGAGAA TAGTCCATCT AAAGGCTTCC AACTCACCCG ACAGGAAATA 
GTTGCTCTTT TAAATGCTTT TGGAAGGCTT TCTACAAGTA TAAGAGACTT ACAGAATTTT 
AAAGTCTTAT TACAACACAG TAGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024304217.1
CDS	1157..1963
Translation	MFGYYAFFFRPRSVYRPLNPLAPSRGEDDGESFYTWLEGLCLEKRVFYKLISGLHASINLHLCANYLLEETWGKPSWGPNIKEFKHRFDPVETKGEGPRRLKNLYFLYLIELRALSKVAPYFERSIVDLYTGNAEEDADTKTLLLNIFQDTKSFPMHFDEKSMFAGDKKGAKSLKEEFRLHFKNISRIMDCVGCDKCRLWGKLQTQGLGTALKILFSEKEIQKLPENSPSKGFQLTRQEIVALLNAFGRLSTSIRDLQNFKVLLQHSR

Target ORF information:

RefSeq Version	XM_024448449.1
Organism	Homo sapiens(human)
Definition	Homo sapiens endoplasmic reticulum oxidoreductase 1 beta (ERO1B), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024448449.1

ORF Insert Sequence:

ATGTTTGGGT ATTATGCTTT CTTTTTCAGG CCTCGATCTG TTTATCGTCC TTTAAATCCT 
CTGGCGCCTA GCCGAGGCGA AGATGATGGA GAATCATTCT ACACATGGCT AGAAGGTTTG 
TGTCTGGAGA AAAGAGTCTT CTATAAGCTT ATATCGGGAC TTCATGCTAG CATCAATTTA 
CATCTATGCG CAAATTATCT TTTGGAAGAA ACCTGGGGTA AGCCCAGTTG GGGACCTAAT 
ATTAAAGAAT TCAAACACCG CTTTGACCCT GTGGAAACCA AGGGAGAAGG TCCAAGAAGG 
CTCAAGAATC TTTACTTTTT ATACTTGATT GAGCTTCGAG CTTTGTCAAA GGTGGCTCCA 
TATTTTGAGC GCTCAATTGT CGATCTTTAC ACTGGAAATG CAGAAGAAGA TGCTGACACA 
AAAACTCTTC TACTGAATAT CTTTCAAGAT ACAAAGTCCT TTCCCATGCA CTTTGATGAG 
AAATCCATGT TTGCAGGTGA CAAAAAAGGG GCCAAGTCAC TAAAGGAGGA ATTCCGATTA 
CATTTCAAGA ATATCTCCCG TATAATGGAC TGTGTTGGAT GTGACAAATG CAGATTATGG 
GGAAAATTAC AGACTCAGGG TTTAGGAACT GCCCTGAAGA TATTATTCTC TGAAAAAGAA 
ATCCAAAAGC TTCCAGAGAA TAGTCCATCT AAAGGCTTCC AACTCACCCG ACAGGAAATA 
GTTGCTCTTT TAAATGCTTT TGGAAGGCTT TCTACAAGTA TAAGAGACTT ACAGAATTTT 
AAAGTCTTAT TACAACACAG TAGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ERO1B ( XM_017001834.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016857323.1 Homo sapiens endoplasmic reticulum oxidoreductase 1 beta (ERO1B), transcript variant X2, mRNA.

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CloneID	OHu90272
Clone ID Related Accession (Same CDS sequence)	XM_017001834.1
Accession Version	XM_017001834.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 792bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	ERO1-like protein beta isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCCAAG GGGTCCGCCG GGCAGGCGCT GGGCAGGGGG TAGCGGCCGC GGTGCAGCTG 
CTGGTCACCC TGAGCTTCCT GCGGAGCGTC GTCGAGGCGC AGGTCACTGG AGTTCTGGAT 
GATTGCTTGT GTGATATTGA CAGCATCGAT AACTTCAATA CCTACAAAAT CTTCCCCAAA 
ATAAAAAAAT TGCAAGAGAG AGACTATTTT CGTTATTACA AGGTTAATCT GAAGCGACCT 
TGTCCTTTCT GGGCAGAAGA TGGCCACTGT TCAATAAAAG ACTGTCATGT GGAGCCCTGT 
CCAGAGAGTA AAATTCCGGT TGGAATAAAA GCTGGGCATT CTAATAAGTA CTTGAAAATG 
GCAAACAATA CCAAAGAATT AGAAGATTGT GAGCAAGCTA ATAAACTGGG AGCAATTAAC 
AGCACATTAA GTAATCAAAG CAAAGAAGCT TTCATTGACT GGGCAAGATA TGATGATTCA 
CGGGATCACT TTTGTGAACT TGATGATGAG AGATCTCCAG CTGCTCAGTA TGTAGACCTA 
TTGCTGAACC CAGAGCGTTA CACTGGCTAT AAAGGGACCT CTGCATGGAG AGTGTGGAAC 
AGCATCTATG AAGAGAACTG TTTCAAGCCT CGATCTGTTT ATCGTCCTTT AAATCCTCTG 
GCGCCTAGCC GAGTGATATA TCAGAGACAT AACACTGCTG AAAAGATGAG GAAAAGGAAA 
CTACTACATA GAAAAAGAGG AAGGGAAGAG GAGAAAAGAA GAAAAATGAA ATATGAAAGA 
AGACAAGACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016857323.1
CDS	176..967
Translation	MSQGVRRAGAGQGVAAAVQLLVTLSFLRSVVEAQVTGVLDDCLCDIDSIDNFNTYKIFPKIKKLQERDYFRYYKVNLKRPCPFWAEDGHCSIKDCHVEPCPESKIPVGIKAGHSNKYLKMANNTKELEDCEQANKLGAINSTLSNQSKEAFIDWARYDDSRDHFCELDDERSPAAQYVDLLLNPERYTGYKGTSAWRVWNSIYEENCFKPRSVYRPLNPLAPSRVIYQRHNTAEKMRKRKLLHRKRGREEEKRRKMKYERRQD

Target ORF information:

RefSeq Version	XM_017001834.1
Organism	Homo sapiens(human)
Definition	Homo sapiens endoplasmic reticulum oxidoreductase 1 beta (ERO1B), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017001834.1

ORF Insert Sequence:

ATGAGCCAAG GGGTCCGCCG GGCAGGCGCT GGGCAGGGGG TAGCGGCCGC GGTGCAGCTG 
CTGGTCACCC TGAGCTTCCT GCGGAGCGTC GTCGAGGCGC AGGTCACTGG AGTTCTGGAT 
GATTGCTTGT GTGATATTGA CAGCATCGAT AACTTCAATA CCTACAAAAT CTTCCCCAAA 
ATAAAAAAAT TGCAAGAGAG AGACTATTTT CGTTATTACA AGGTTAATCT GAAGCGACCT 
TGTCCTTTCT GGGCAGAAGA TGGCCACTGT TCAATAAAAG ACTGTCATGT GGAGCCCTGT 
CCAGAGAGTA AAATTCCGGT TGGAATAAAA GCTGGGCATT CTAATAAGTA CTTGAAAATG 
GCAAACAATA CCAAAGAATT AGAAGATTGT GAGCAAGCTA ATAAACTGGG AGCAATTAAC 
AGCACATTAA GTAATCAAAG CAAAGAAGCT TTCATTGACT GGGCAAGATA TGATGATTCA 
CGGGATCACT TTTGTGAACT TGATGATGAG AGATCTCCAG CTGCTCAGTA TGTAGACCTA 
TTGCTGAACC CAGAGCGTTA CACTGGCTAT AAAGGGACCT CTGCATGGAG AGTGTGGAAC 
AGCATCTATG AAGAGAACTG TTTCAAGCCT CGATCTGTTT ATCGTCCTTT AAATCCTCTG 
GCGCCTAGCC GAGTGATATA TCAGAGACAT AACACTGCTG AAAAGATGAG GAAAAGGAAA 
CTACTACATA GAAAAAGAGG AAGGGAAGAG GAGAAAAGAA GAAAAATGAA ATATGAAAGA 
AGACAAGACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genome-scale analysis identifies GJB2 and ERO1LB as prognosis markers in patients with pancreatic cancer.
Oncotarget8(13)21281-21289(2017 Mar)
Zhu T,Gao YF,Chen YX,Wang ZB,Yin JY,Mao XY,Li X,Zhang W,Zhou HH,Liu ZQ

The Immunohistochemical Evaluation of Solid Pseudopapillary Tumors of the Pancreas and Pancreatic Neuroendocrine Tumors Reveals ERO1L? as a New Biomarker.
Medicine95(2)e2509(2016 Jan)
Xie J,Zhu Y,Chen H,Shi M,Gu J,Zhang J,Shen B,Deng X,Zhan X,Peng C

Biochemical evidence that regulation of Ero1? activity in human cells does not involve the isoform-specific cysteine 262.
Bioscience reports34(2)(2014 Apr)
Hansen HG,S?ltoft CL,Schmidt JD,Birk J,Appenzeller-Herzog C,Ellgaard L

The endoplasmic reticulum sulfhydryl oxidase Ero1? drives efficient oxidative protein folding with loose regulation.
The Biochemical journal434(1)113-21(2011 Feb)
Wang L,Zhu L,Wang CC