CDCA7L cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CDCA7L
Entrez Gene ID	55536
Full Name	cell division cycle associated 7 like
Synonyms	JPO2,R1,RAM2
General protein information	Preferred Names cell division cycle associated 7 like Names cell division cycle-associated 7-like protein transcription factor RAM2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7p15.3
Disorder MIM:	609685

mRNA and Protein(s)

mRNA	Protein	Name
NM_018719.4	NP_061189.2	cell division cycle-associated 7-like protein isoform 1
NM_001127370.3	NP_001120842.1	cell division cycle-associated 7-like protein isoform 2
NM_001127370.2	NP_001120842.1	cell division cycle-associated 7-like protein isoform 2
NM_001127371.3	NP_001120843.1	cell division cycle-associated 7-like protein isoform 3
NM_001127371.2	NP_001120843.1	cell division cycle-associated 7-like protein isoform 3
NM_018719.5	NP_061189.2	cell division cycle-associated 7-like protein isoform 1

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	cdca7l	XP_002933330.1
Homo sapiens (human)	CDCA7L	NP_061189.2
Pan troglodytes (chimpanzee)	CDCA7L	XP_527681.2
Mus musculus (house mouse)	Cdca7l	NP_666152.1
Danio rerio (zebrafish)	cdca7b	XP_002665508.2
	CDCA7L	XP_001100802.2
Canis lupus familiaris (dog)	CDCA7L	XP_005628670.1
Rattus norvegicus (Norway rat)	Cdca7l	NP_001030125.1
Gallus gallus (chicken)	CDCA7L	NP_001026153.1
Bos taurus (cattle)	CDCA7L	NP_001098447.1

Gene Ontology
Bibliography

Related articles in PubMed

Multiple myeloma risk variant at 7p15.3 creates an IRF4-binding site and interferes with CDCA7L expression.
Li N, Johnson DC, Weinhold N, Studd JB, Orlando G, Mirabella F, Mitchell JS, Meissner T, Kaiser M, Goldschmidt H, Hemminki K, Morgan GJ, Houlston RS
Nature communications713656(2016 Nov)

JPO2/CDCA7L and LEDGF/p75 Are Novel Mediators of PI3K/AKT Signaling and Aggressive Phenotypes in Medulloblastoma.
Chan TS, Hawkins C, Krieger JR, McGlade CJ, Huang A
Cancer research76(9)2802-12(2016 05)

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Yang X, Coulombe-Huntington J, Kang S, Sheynkman GM, Hao T, Richardson A, Sun S, Yang F, Shen YA, Murray RR, Spirohn K, Begg BE, Duran-Frigola M, MacWilliams A, Pevzner SJ, Zhong Q, Trigg SA, Tam S, Ghamsari L, Sahni N, Yi S, Rodriguez MD, Balcha D, Tan G, Costanzo M, Andrews B, Boone C, Zhou XJ, Salehi-Ashtiani K, Charloteaux B, Chen AA, Calderwood MA, Aloy P, Roth FP, Hill DE, Iakoucheva LM, Xia Y, Vidal M
Cell164(4)805-17(2016 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

We identify the Myc-interacting protein JPO2 and its partner binding protein LEDGF/p75 as critical modulators of PI3K/AKT signaling and metastasis in medulloblastoma
Title: JPO2/CDCA7L and LEDGF/p75 Are Novel Mediators of PI3K/AKT Signaling and Aggressive Phenotypes in Medulloblastoma.

common LEDGF/p75 interaction interface shared by JPO2, PogZ, MLL1, IWS1 and HIV IN
Title: Multiple cellular proteins interact with LEDGF/p75 through a conserved unstructured consensus motif.

The data are consistent with the rs4487645-CDCA7L loci being responsible for the chromosome 7p11.2 association with multiple myeloma risk, probably exerting its effects through an extended pathway involving IRF4 and MYC.
Title: The 7p15.3 (rs4487645) association for multiple myeloma shows strong allele-specific regulation of the MYC-interacting gene CDCA7L in malignant plasma cells.

Data indicate that JPO2 and LEDGF/p75 interact directly and specifically in vivo through the specific interaction domain of JPO2 and the C-terminal domain of LEDGF/p75.
Title: Dynamics of the ternary complex formed by c-Myc interactor JPO2, transcriptional co-activator LEDGF/p75, and chromatin.

CDCA7L was able to activate the extracellular signal-regulated kinase 1/2 (ERK1/2) signaling pathway and regulate the cell cycle, thus promoting HCC progression.
Title: CDCA7L promotes hepatocellular carcinoma progression by regulating the cell cycle.

The following CDCA7L gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CDCA7L cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu02849	NM_018719.5 Latest version!	Homo sapiens cell division cycle associated 7 like (CDCA7L), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu06712	NM_001127370.3 Latest version!	Homo sapiens cell division cycle associated 7 like (CDCA7L), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu06713	NM_001127371.3 Latest version!	Homo sapiens cell division cycle associated 7 like (CDCA7L), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OHu06712	NM_001127370.2	Homo sapiens cell division cycle associated 7 like (CDCA7L), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu06713	NM_001127371.2	Homo sapiens cell division cycle associated 7 like (CDCA7L), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu02849	NM_018719.4	Homo sapiens cell division cycle associated 7 like (CDCA7L), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CDCA7L ( NM_018719.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_061189.2 Homo sapiens cell division cycle associated 7 like (CDCA7L), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu02849
Clone ID Related Accession (Same CDS sequence)	NM_018719.4 , NM_018719.5
Accession Version	NM_018719.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1365bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-27
Organism	Homo sapiens(human)
Product	cell division cycle-associated 7-like protein isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA041070.1, AK292490.1, BC009352.2, AL576822.3, AA922229.1, AK022955.1 and BU753973.1. On Apr 4, 2009 this sequence version replaced NM_018719.3. Transcript Variant: This variant (1) encodes the predominant and longest protein (isoform 1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC009352.2, SRR1803615.54863.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGGAGTTGG CGACTCGCTA CCAGATCCCT AAAGAAGTGG CTGACATCTT TAACGCCCCC 
AGTGATGATG AAGAGTTTGT TGGCTTCCGA GATGATGTTC CCATGGAAAC CCTCTCGTCA 
GAGGAGAGCT GCGATAGTTT TGACTCACTA GAGTCAGGGA AACAGCAGGA TGTGCGCTTT 
CATTCCAAAT ACTTCACAGA AGAGCTAAGA AGAATTTTTA TAGAGGACAC TGACTCAGAG 
ACTGAGGATT TTGCAGGATT TACGCAGAGT GATCTGAATG GAAAGACTAA CCCAGAAGTA 
ATGGTCGTGG AGTCAGATTT GAGTGATGAT GGCAAAGCAT CTTTGGTGAG CGAGGAAGAG 
GAAGATGAAG AAGAAGATAA GGCTACCCCT AGAAGAAGCA GGTCTAGAAG AAGTAGTATT 
GGTCTTCGAG TAGCCTTTCA GTTCCCCACC AAGAAGCTGG CCAACAAACC AGATAAAAAC 
AGTTCTTCCG AGCAGTTGTT TTCTAGCGCA CGCTTACAGA ATGAGAAAAA AACAATTCTT 
GAAAGAAAGA AAGACTGTAG ACAGGTGATA CAAAGGGAAG ATTCTACCTC TGAGTCTGAG 
GATGACTCTC GGGATGAGAG CCAGGAGAGT TCAGATGCTT TGCTGAAAAG GACCATGAAC 
ATCAAGGAGA ACAAAGCCAT GCTTGCCCAG TTATTGGCGG AATTGAACTC GATGCCAGAT 
TTCTTCCCAG TACGAACCCC AACCTCAGCT TCTAGGAAGA AGACAGTGAG GCGGGCCTTC 
TCGGAGGGAC AGATCACGCG GCGTATGAAC CCAACCCGGA GTGCGCGGCC TCCTGAGAAG 
TTTGCTCTAG AGAACTTCAC TGTCTCAGCC GCTAAATTTG CGGAAGAGTT TTACAGCTTC 
CGAAGAAGGA AGACAATTGG GGGGAAATGC CGGGAGTACA GACGACGTCA CCGTATATCT 
TCTTTTCGGC CAGTGGAGGA TATCACCGAA GAGGACTTAG AAAATGTTGC CATAACTGTT 
CGAGATAAAA TCTATGATAA AGTTCTGGGT AACACGTGCC ATCAGTGTCG ACAAAAGACC 
ATCGACACCA AGACAGTGTG TCGGAACCAG GGTTGCTGTG GTGTGCGAGG ACAGTTCTGT 
GGACCATGCC TGCGGAACCG CTATGGGGAG GATGTCAGAT CGGCATTGCT GGACCCGGAT 
TGGGTGTGTC CCCCCTGTCG TGGGATCTGC AATTGCAGCT ACTGTCGGAA GCGTGACGGC 
CGCTGTGCCA CAGGAATCCT CATTCATCTG GCCAAGTTTT ATGGTTATGA CAATGTTAAG 
GAATATCTGG AGAGCTTACA AAAGGAGCTG GTAGAAGACA ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061189.2
CDS	121..1485
Translation	MELATRYQIPKEVADIFNAPSDDEEFVGFRDDVPMETLSSEESCDSFDSLESGKQQDVRFHSKYFTEELRRIFIEDTDSETEDFAGFTQSDLNGKTNPEVMVVESDLSDDGKASLVSEEEEDEEEDKATPRRSRSRRSSIGLRVAFQFPTKKLANKPDKNSSSEQLFSSARLQNEKKTILERKKDCRQVIQREDSTSESEDDSRDESQESSDALLKRTMNIKENKAMLAQLLAELNSMPDFFPVRTPTSASRKKTVRRAFSEGQITRRMNPTRSARPPEKFALENFTVSAAKFAEEFYSFRRRKTIGGKCREYRRRHRISSFRPVEDITEEDLENVAITVRDKIYDKVLGNTCHQCRQKTIDTKTVCRNQGCCGVRGQFCGPCLRNRYGEDVRSALLDPDWVCPPCRGICNCSYCRKRDGRCATGILIHLAKFYGYDNVKEYLESLQKELVEDN

Target ORF information:

RefSeq Version	NM_018719.4
Organism	Homo sapiens(human)
Definition	Homo sapiens cell division cycle associated 7 like (CDCA7L), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018719.4

ORF Insert Sequence:

ATGGAGTTGG CGACTCGCTA CCAGATCCCT AAAGAAGTGG CTGACATCTT TAACGCCCCC 
AGTGATGATG AAGAGTTTGT TGGCTTCCGA GATGATGTTC CCATGGAAAC CCTCTCGTCA 
GAGGAGAGCT GCGATAGTTT TGACTCACTA GAGTCAGGGA AACAGCAGGA TGTGCGCTTT 
CATTCCAAAT ACTTCACAGA AGAGCTAAGA AGAATTTTTA TAGAGGACAC TGACTCAGAG 
ACTGAGGATT TTGCAGGATT TACGCAGAGT GATCTGAATG GAAAGACTAA CCCAGAAGTA 
ATGGTCGTGG AGTCAGATTT GAGTGATGAT GGCAAAGCAT CTTTGGTGAG CGAGGAAGAG 
GAAGATGAAG AAGAAGATAA GGCTACCCCT AGAAGAAGCA GGTCTAGAAG AAGTAGTATT 
GGTCTTCGAG TAGCCTTTCA GTTCCCCACC AAGAAGCTGG CCAACAAACC AGATAAAAAC 
AGTTCTTCCG AGCAGTTGTT TTCTAGCGCA CGCTTACAGA ATGAGAAAAA AACAATTCTT 
GAAAGAAAGA AAGACTGTAG ACAGGTGATA CAAAGGGAAG ATTCTACCTC TGAGTCTGAG 
GATGACTCTC GGGATGAGAG CCAGGAGAGT TCAGATGCTT TGCTGAAAAG GACCATGAAC 
ATCAAGGAGA ACAAAGCCAT GCTTGCCCAG TTATTGGCGG AATTGAACTC GATGCCAGAT 
TTCTTCCCAG TACGAACCCC AACCTCAGCT TCTAGGAAGA AGACAGTGAG GCGGGCCTTC 
TCGGAGGGAC AGATCACGCG GCGTATGAAC CCAACCCGGA GTGCGCGGCC TCCTGAGAAG 
TTTGCTCTAG AGAACTTCAC TGTCTCAGCC GCTAAATTTG CGGAAGAGTT TTACAGCTTC 
CGAAGAAGGA AGACAATTGG GGGGAAATGC CGGGAGTACA GACGACGTCA CCGTATATCT 
TCTTTTCGGC CAGTGGAGGA TATCACCGAA GAGGACTTAG AAAATGTTGC CATAACTGTT 
CGAGATAAAA TCTATGATAA AGTTCTGGGT AACACGTGCC ATCAGTGTCG ACAAAAGACC 
ATCGACACCA AGACAGTGTG TCGGAACCAG GGTTGCTGTG GTGTGCGAGG ACAGTTCTGT 
GGACCATGCC TGCGGAACCG CTATGGGGAG GATGTCAGAT CGGCATTGCT GGACCCGGAT 
TGGGTGTGTC CCCCCTGTCG TGGGATCTGC AATTGCAGCT ACTGTCGGAA GCGTGACGGC 
CGCTGTGCCA CAGGAATCCT CATTCATCTG GCCAAGTTTT ATGGTTATGA CAATGTTAAG 
GAATATCTGG AGAGCTTACA AAAGGAGCTG GTAGAAGACA ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDCA7L ( NM_018719.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_061189.2 Homo sapiens cell division cycle associated 7 like (CDCA7L), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu02849
Clone ID Related Accession (Same CDS sequence)	NM_018719.4 , NM_018719.5
Accession Version	NM_018719.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1365bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-16
Organism	Homo sapiens(human)
Product	cell division cycle-associated 7-like protein isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK292490.1, BC009352.2, AL576822.3, AA922229.1, AK022955.1 and BU753973.1. On Nov 23, 2018 this sequence version replaced NM_018719.4. Transcript Variant: This variant (1) encodes the predominant and longest protein (isoform 1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.8454.1, BC039823.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000406877.8/ ENSP00000383986.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGTTGG CGACTCGCTA CCAGATCCCT AAAGAAGTGG CTGACATCTT TAACGCCCCC 
AGTGATGATG AAGAGTTTGT TGGCTTCCGA GATGATGTTC CCATGGAAAC CCTCTCGTCA 
GAGGAGAGCT GCGATAGTTT TGACTCACTA GAGTCAGGGA AACAGCAGGA TGTGCGCTTT 
CATTCCAAAT ACTTCACAGA AGAGCTAAGA AGAATTTTTA TAGAGGACAC TGACTCAGAG 
ACTGAGGATT TTGCAGGATT TACGCAGAGT GATCTGAATG GAAAGACTAA CCCAGAAGTA 
ATGGTCGTGG AGTCAGATTT GAGTGATGAT GGCAAAGCAT CTTTGGTGAG CGAGGAAGAG 
GAAGATGAAG AAGAAGATAA GGCTACCCCT AGAAGAAGCA GGTCTAGAAG AAGTAGTATT 
GGTCTTCGAG TAGCCTTTCA GTTCCCCACC AAGAAGCTGG CCAACAAACC AGATAAAAAC 
AGTTCTTCCG AGCAGTTGTT TTCTAGCGCA CGCTTACAGA ATGAGAAAAA AACAATTCTT 
GAAAGAAAGA AAGACTGTAG ACAGGTGATA CAAAGGGAAG ATTCTACCTC TGAGTCTGAG 
GATGACTCTC GGGATGAGAG CCAGGAGAGT TCAGATGCTT TGCTGAAAAG GACCATGAAC 
ATCAAGGAGA ACAAAGCCAT GCTTGCCCAG TTATTGGCGG AATTGAACTC GATGCCAGAT 
TTCTTCCCAG TACGAACCCC AACCTCAGCT TCTAGGAAGA AGACAGTGAG GCGGGCCTTC 
TCGGAGGGAC AGATCACGCG GCGTATGAAC CCAACCCGGA GTGCGCGGCC TCCTGAGAAG 
TTTGCTCTAG AGAACTTCAC TGTCTCAGCC GCTAAATTTG CGGAAGAGTT TTACAGCTTC 
CGAAGAAGGA AGACAATTGG GGGGAAATGC CGGGAGTACA GACGACGTCA CCGTATATCT 
TCTTTTCGGC CAGTGGAGGA TATCACCGAA GAGGACTTAG AAAATGTTGC CATAACTGTT 
CGAGATAAAA TCTATGATAA AGTTCTGGGT AACACGTGCC ATCAGTGTCG ACAAAAGACC 
ATCGACACCA AGACAGTGTG TCGGAACCAG GGTTGCTGTG GTGTGCGAGG ACAGTTCTGT 
GGACCATGCC TGCGGAACCG CTATGGGGAG GATGTCAGAT CGGCATTGCT GGACCCGGAT 
TGGGTGTGTC CCCCCTGTCG TGGGATCTGC AATTGCAGCT ACTGTCGGAA GCGTGACGGC 
CGCTGTGCCA CAGGAATCCT CATTCATCTG GCCAAGTTTT ATGGTTATGA CAATGTTAAG 
GAATATCTGG AGAGCTTACA AAAGGAGCTG GTAGAAGACA ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061189.2
CDS	96..1460
Translation	MELATRYQIPKEVADIFNAPSDDEEFVGFRDDVPMETLSSEESCDSFDSLESGKQQDVRFHSKYFTEELRRIFIEDTDSETEDFAGFTQSDLNGKTNPEVMVVESDLSDDGKASLVSEEEEDEEEDKATPRRSRSRRSSIGLRVAFQFPTKKLANKPDKNSSSEQLFSSARLQNEKKTILERKKDCRQVIQREDSTSESEDDSRDESQESSDALLKRTMNIKENKAMLAQLLAELNSMPDFFPVRTPTSASRKKTVRRAFSEGQITRRMNPTRSARPPEKFALENFTVSAAKFAEEFYSFRRRKTIGGKCREYRRRHRISSFRPVEDITEEDLENVAITVRDKIYDKVLGNTCHQCRQKTIDTKTVCRNQGCCGVRGQFCGPCLRNRYGEDVRSALLDPDWVCPPCRGICNCSYCRKRDGRCATGILIHLAKFYGYDNVKEYLESLQKELVEDN

Target ORF information:

RefSeq Version	NM_018719.5
Organism	Homo sapiens(human)
Definition	Homo sapiens cell division cycle associated 7 like (CDCA7L), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018719.5

ORF Insert Sequence:

ATGGAGTTGG CGACTCGCTA CCAGATCCCT AAAGAAGTGG CTGACATCTT TAACGCCCCC 
AGTGATGATG AAGAGTTTGT TGGCTTCCGA GATGATGTTC CCATGGAAAC CCTCTCGTCA 
GAGGAGAGCT GCGATAGTTT TGACTCACTA GAGTCAGGGA AACAGCAGGA TGTGCGCTTT 
CATTCCAAAT ACTTCACAGA AGAGCTAAGA AGAATTTTTA TAGAGGACAC TGACTCAGAG 
ACTGAGGATT TTGCAGGATT TACGCAGAGT GATCTGAATG GAAAGACTAA CCCAGAAGTA 
ATGGTCGTGG AGTCAGATTT GAGTGATGAT GGCAAAGCAT CTTTGGTGAG CGAGGAAGAG 
GAAGATGAAG AAGAAGATAA GGCTACCCCT AGAAGAAGCA GGTCTAGAAG AAGTAGTATT 
GGTCTTCGAG TAGCCTTTCA GTTCCCCACC AAGAAGCTGG CCAACAAACC AGATAAAAAC 
AGTTCTTCCG AGCAGTTGTT TTCTAGCGCA CGCTTACAGA ATGAGAAAAA AACAATTCTT 
GAAAGAAAGA AAGACTGTAG ACAGGTGATA CAAAGGGAAG ATTCTACCTC TGAGTCTGAG 
GATGACTCTC GGGATGAGAG CCAGGAGAGT TCAGATGCTT TGCTGAAAAG GACCATGAAC 
ATCAAGGAGA ACAAAGCCAT GCTTGCCCAG TTATTGGCGG AATTGAACTC GATGCCAGAT 
TTCTTCCCAG TACGAACCCC AACCTCAGCT TCTAGGAAGA AGACAGTGAG GCGGGCCTTC 
TCGGAGGGAC AGATCACGCG GCGTATGAAC CCAACCCGGA GTGCGCGGCC TCCTGAGAAG 
TTTGCTCTAG AGAACTTCAC TGTCTCAGCC GCTAAATTTG CGGAAGAGTT TTACAGCTTC 
CGAAGAAGGA AGACAATTGG GGGGAAATGC CGGGAGTACA GACGACGTCA CCGTATATCT 
TCTTTTCGGC CAGTGGAGGA TATCACCGAA GAGGACTTAG AAAATGTTGC CATAACTGTT 
CGAGATAAAA TCTATGATAA AGTTCTGGGT AACACGTGCC ATCAGTGTCG ACAAAAGACC 
ATCGACACCA AGACAGTGTG TCGGAACCAG GGTTGCTGTG GTGTGCGAGG ACAGTTCTGT 
GGACCATGCC TGCGGAACCG CTATGGGGAG GATGTCAGAT CGGCATTGCT GGACCCGGAT 
TGGGTGTGTC CCCCCTGTCG TGGGATCTGC AATTGCAGCT ACTGTCGGAA GCGTGACGGC 
CGCTGTGCCA CAGGAATCCT CATTCATCTG GCCAAGTTTT ATGGTTATGA CAATGTTAAG 
GAATATCTGG AGAGCTTACA AAAGGAGCTG GTAGAAGACA ATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDCA7L ( NM_001127370.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001120842.1 Homo sapiens cell division cycle associated 7 like (CDCA7L), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu06712
Clone ID Related Accession (Same CDS sequence)	NM_001127370.3 , NM_001127370.2
Accession Version	NM_001127370.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1263bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-02
Organism	Homo sapiens(human)
Product	cell division cycle-associated 7-like protein isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA041070.1, AK095965.1, BC009352.2, AL576822.3, AA922229.1, AK022955.1 and BU753973.1. On May 31, 2019 this sequence version replaced NM_001127370.2. Transcript Variant: This variant (2) includes an alternate exon in the 5' UTR which results in the use of a downstream start codon, compared to variant 1. Isoform 2 has a shorter N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.204542.1, AK095965.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGGAAACCC TCTCGTCAGA GGAGAGCTGC GATAGTTTTG ACTCACTAGA GTCAGGGAAA 
CAGCAGGATG TGCGCTTTCA TTCCAAATAC TTCACAGAAG AGCTAAGAAG AATTTTTATA 
GAGGACACTG ACTCAGAGAC TGAGGATTTT GCAGGATTTA CGCAGAGTGA TCTGAATGGA 
AAGACTAACC CAGAAGTAAT GGTCGTGGAG TCAGATTTGA GTGATGATGG CAAAGCATCT 
TTGGTGAGCG AGGAAGAGGA AGATGAAGAA GAAGATAAGG CTACCCCTAG AAGAAGCAGG 
TCTAGAAGAA GTAGTATTGG TCTTCGAGTA GCCTTTCAGT TCCCCACCAA GAAGCTGGCC 
AACAAACCAG ATAAAAACAG TTCTTCCGAG CAGTTGTTTT CTAGCGCACG CTTACAGAAT 
GAGAAAAAAA CAATTCTTGA AAGAAAGAAA GACTGTAGAC AGGTGATACA AAGGGAAGAT 
TCTACCTCTG AGTCTGAGGA TGACTCTCGG GATGAGAGCC AGGAGAGTTC AGATGCTTTG 
CTGAAAAGGA CCATGAACAT CAAGGAGAAC AAAGCCATGC TTGCCCAGTT ATTGGCGGAA 
TTGAACTCGA TGCCAGATTT CTTCCCAGTA CGAACCCCAA CCTCAGCTTC TAGGAAGAAG 
ACAGTGAGGC GGGCCTTCTC GGAGGGACAG ATCACGCGGC GTATGAACCC AACCCGGAGT 
GCGCGGCCTC CTGAGAAGTT TGCTCTAGAG AACTTCACTG TCTCAGCCGC TAAATTTGCG 
GAAGAGTTTT ACAGCTTCCG AAGAAGGAAG ACAATTGGGG GGAAATGCCG GGAGTACAGA 
CGACGTCACC GTATATCTTC TTTTCGGCCA GTGGAGGATA TCACCGAAGA GGACTTAGAA 
AATGTTGCCA TAACTGTTCG AGATAAAATC TATGATAAAG TTCTGGGTAA CACGTGCCAT 
CAGTGTCGAC AAAAGACCAT CGACACCAAG ACAGTGTGTC GGAACCAGGG TTGCTGTGGT 
GTGCGAGGAC AGTTCTGTGG ACCATGCCTG CGGAACCGCT ATGGGGAGGA TGTCAGATCG 
GCATTGCTGG ACCCGGATTG GGTGTGTCCC CCCTGTCGTG GGATCTGCAA TTGCAGCTAC 
TGTCGGAAGC GTGACGGCCG CTGTGCCACA GGAATCCTCA TTCATCTGGC CAAGTTTTAT 
GGTTATGACA ATGTTAAGGA ATATCTGGAG AGCTTACAAA AGGAGCTGGT AGAAGACAAT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001120842.1
CDS	252..1514
Translation	METLSSEESCDSFDSLESGKQQDVRFHSKYFTEELRRIFIEDTDSETEDFAGFTQSDLNGKTNPEVMVVESDLSDDGKASLVSEEEEDEEEDKATPRRSRSRRSSIGLRVAFQFPTKKLANKPDKNSSSEQLFSSARLQNEKKTILERKKDCRQVIQREDSTSESEDDSRDESQESSDALLKRTMNIKENKAMLAQLLAELNSMPDFFPVRTPTSASRKKTVRRAFSEGQITRRMNPTRSARPPEKFALENFTVSAAKFAEEFYSFRRRKTIGGKCREYRRRHRISSFRPVEDITEEDLENVAITVRDKIYDKVLGNTCHQCRQKTIDTKTVCRNQGCCGVRGQFCGPCLRNRYGEDVRSALLDPDWVCPPCRGICNCSYCRKRDGRCATGILIHLAKFYGYDNVKEYLESLQKELVEDN

Target ORF information:

RefSeq Version	NM_001127370.3
Organism	Homo sapiens(human)
Definition	Homo sapiens cell division cycle associated 7 like (CDCA7L), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001127370.3

ORF Insert Sequence:

ATGGAAACCC TCTCGTCAGA GGAGAGCTGC GATAGTTTTG ACTCACTAGA GTCAGGGAAA 
CAGCAGGATG TGCGCTTTCA TTCCAAATAC TTCACAGAAG AGCTAAGAAG AATTTTTATA 
GAGGACACTG ACTCAGAGAC TGAGGATTTT GCAGGATTTA CGCAGAGTGA TCTGAATGGA 
AAGACTAACC CAGAAGTAAT GGTCGTGGAG TCAGATTTGA GTGATGATGG CAAAGCATCT 
TTGGTGAGCG AGGAAGAGGA AGATGAAGAA GAAGATAAGG CTACCCCTAG AAGAAGCAGG 
TCTAGAAGAA GTAGTATTGG TCTTCGAGTA GCCTTTCAGT TCCCCACCAA GAAGCTGGCC 
AACAAACCAG ATAAAAACAG TTCTTCCGAG CAGTTGTTTT CTAGCGCACG CTTACAGAAT 
GAGAAAAAAA CAATTCTTGA AAGAAAGAAA GACTGTAGAC AGGTGATACA AAGGGAAGAT 
TCTACCTCTG AGTCTGAGGA TGACTCTCGG GATGAGAGCC AGGAGAGTTC AGATGCTTTG 
CTGAAAAGGA CCATGAACAT CAAGGAGAAC AAAGCCATGC TTGCCCAGTT ATTGGCGGAA 
TTGAACTCGA TGCCAGATTT CTTCCCAGTA CGAACCCCAA CCTCAGCTTC TAGGAAGAAG 
ACAGTGAGGC GGGCCTTCTC GGAGGGACAG ATCACGCGGC GTATGAACCC AACCCGGAGT 
GCGCGGCCTC CTGAGAAGTT TGCTCTAGAG AACTTCACTG TCTCAGCCGC TAAATTTGCG 
GAAGAGTTTT ACAGCTTCCG AAGAAGGAAG ACAATTGGGG GGAAATGCCG GGAGTACAGA 
CGACGTCACC GTATATCTTC TTTTCGGCCA GTGGAGGATA TCACCGAAGA GGACTTAGAA 
AATGTTGCCA TAACTGTTCG AGATAAAATC TATGATAAAG TTCTGGGTAA CACGTGCCAT 
CAGTGTCGAC AAAAGACCAT CGACACCAAG ACAGTGTGTC GGAACCAGGG TTGCTGTGGT 
GTGCGAGGAC AGTTCTGTGG ACCATGCCTG CGGAACCGCT ATGGGGAGGA TGTCAGATCG 
GCATTGCTGG ACCCGGATTG GGTGTGTCCC CCCTGTCGTG GGATCTGCAA TTGCAGCTAC 
TGTCGGAAGC GTGACGGCCG CTGTGCCACA GGAATCCTCA TTCATCTGGC CAAGTTTTAT 
GGTTATGACA ATGTTAAGGA ATATCTGGAG AGCTTACAAA AGGAGCTGGT AGAAGACAAT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDCA7L ( NM_001127370.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001120842.1 Homo sapiens cell division cycle associated 7 like (CDCA7L), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu06712
Clone ID Related Accession (Same CDS sequence)	NM_001127370.3 , NM_001127370.2
Accession Version	NM_001127370.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1263bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-09
Organism	Homo sapiens(human)
Product	cell division cycle-associated 7-like protein isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA041070.1, AK095965.1, BC009352.2, AL576822.3, AA922229.1, AK022955.1 and BU753973.1. On Apr 4, 2009 this sequence version replaced NM_001127370.1. Transcript Variant: This variant (2) includes an alternate exon in the 5' UTR which results in the use of a downstream start codon, compared to variant 1. Isoform 2 has a shorter N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK095965.1, SRR1803612.15131.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGGAAACCC TCTCGTCAGA GGAGAGCTGC GATAGTTTTG ACTCACTAGA GTCAGGGAAA 
CAGCAGGATG TGCGCTTTCA TTCCAAATAC TTCACAGAAG AGCTAAGAAG AATTTTTATA 
GAGGACACTG ACTCAGAGAC TGAGGATTTT GCAGGATTTA CGCAGAGTGA TCTGAATGGA 
AAGACTAACC CAGAAGTAAT GGTCGTGGAG TCAGATTTGA GTGATGATGG CAAAGCATCT 
TTGGTGAGCG AGGAAGAGGA AGATGAAGAA GAAGATAAGG CTACCCCTAG AAGAAGCAGG 
TCTAGAAGAA GTAGTATTGG TCTTCGAGTA GCCTTTCAGT TCCCCACCAA GAAGCTGGCC 
AACAAACCAG ATAAAAACAG TTCTTCCGAG CAGTTGTTTT CTAGCGCACG CTTACAGAAT 
GAGAAAAAAA CAATTCTTGA AAGAAAGAAA GACTGTAGAC AGGTGATACA AAGGGAAGAT 
TCTACCTCTG AGTCTGAGGA TGACTCTCGG GATGAGAGCC AGGAGAGTTC AGATGCTTTG 
CTGAAAAGGA CCATGAACAT CAAGGAGAAC AAAGCCATGC TTGCCCAGTT ATTGGCGGAA 
TTGAACTCGA TGCCAGATTT CTTCCCAGTA CGAACCCCAA CCTCAGCTTC TAGGAAGAAG 
ACAGTGAGGC GGGCCTTCTC GGAGGGACAG ATCACGCGGC GTATGAACCC AACCCGGAGT 
GCGCGGCCTC CTGAGAAGTT TGCTCTAGAG AACTTCACTG TCTCAGCCGC TAAATTTGCG 
GAAGAGTTTT ACAGCTTCCG AAGAAGGAAG ACAATTGGGG GGAAATGCCG GGAGTACAGA 
CGACGTCACC GTATATCTTC TTTTCGGCCA GTGGAGGATA TCACCGAAGA GGACTTAGAA 
AATGTTGCCA TAACTGTTCG AGATAAAATC TATGATAAAG TTCTGGGTAA CACGTGCCAT 
CAGTGTCGAC AAAAGACCAT CGACACCAAG ACAGTGTGTC GGAACCAGGG TTGCTGTGGT 
GTGCGAGGAC AGTTCTGTGG ACCATGCCTG CGGAACCGCT ATGGGGAGGA TGTCAGATCG 
GCATTGCTGG ACCCGGATTG GGTGTGTCCC CCCTGTCGTG GGATCTGCAA TTGCAGCTAC 
TGTCGGAAGC GTGACGGCCG CTGTGCCACA GGAATCCTCA TTCATCTGGC CAAGTTTTAT 
GGTTATGACA ATGTTAAGGA ATATCTGGAG AGCTTACAAA AGGAGCTGGT AGAAGACAAT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001120842.1
CDS	277..1539
Translation	METLSSEESCDSFDSLESGKQQDVRFHSKYFTEELRRIFIEDTDSETEDFAGFTQSDLNGKTNPEVMVVESDLSDDGKASLVSEEEEDEEEDKATPRRSRSRRSSIGLRVAFQFPTKKLANKPDKNSSSEQLFSSARLQNEKKTILERKKDCRQVIQREDSTSESEDDSRDESQESSDALLKRTMNIKENKAMLAQLLAELNSMPDFFPVRTPTSASRKKTVRRAFSEGQITRRMNPTRSARPPEKFALENFTVSAAKFAEEFYSFRRRKTIGGKCREYRRRHRISSFRPVEDITEEDLENVAITVRDKIYDKVLGNTCHQCRQKTIDTKTVCRNQGCCGVRGQFCGPCLRNRYGEDVRSALLDPDWVCPPCRGICNCSYCRKRDGRCATGILIHLAKFYGYDNVKEYLESLQKELVEDN

Target ORF information:

RefSeq Version	NM_001127370.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cell division cycle associated 7 like (CDCA7L), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001127370.2

ORF Insert Sequence:

ATGGAAACCC TCTCGTCAGA GGAGAGCTGC GATAGTTTTG ACTCACTAGA GTCAGGGAAA 
CAGCAGGATG TGCGCTTTCA TTCCAAATAC TTCACAGAAG AGCTAAGAAG AATTTTTATA 
GAGGACACTG ACTCAGAGAC TGAGGATTTT GCAGGATTTA CGCAGAGTGA TCTGAATGGA 
AAGACTAACC CAGAAGTAAT GGTCGTGGAG TCAGATTTGA GTGATGATGG CAAAGCATCT 
TTGGTGAGCG AGGAAGAGGA AGATGAAGAA GAAGATAAGG CTACCCCTAG AAGAAGCAGG 
TCTAGAAGAA GTAGTATTGG TCTTCGAGTA GCCTTTCAGT TCCCCACCAA GAAGCTGGCC 
AACAAACCAG ATAAAAACAG TTCTTCCGAG CAGTTGTTTT CTAGCGCACG CTTACAGAAT 
GAGAAAAAAA CAATTCTTGA AAGAAAGAAA GACTGTAGAC AGGTGATACA AAGGGAAGAT 
TCTACCTCTG AGTCTGAGGA TGACTCTCGG GATGAGAGCC AGGAGAGTTC AGATGCTTTG 
CTGAAAAGGA CCATGAACAT CAAGGAGAAC AAAGCCATGC TTGCCCAGTT ATTGGCGGAA 
TTGAACTCGA TGCCAGATTT CTTCCCAGTA CGAACCCCAA CCTCAGCTTC TAGGAAGAAG 
ACAGTGAGGC GGGCCTTCTC GGAGGGACAG ATCACGCGGC GTATGAACCC AACCCGGAGT 
GCGCGGCCTC CTGAGAAGTT TGCTCTAGAG AACTTCACTG TCTCAGCCGC TAAATTTGCG 
GAAGAGTTTT ACAGCTTCCG AAGAAGGAAG ACAATTGGGG GGAAATGCCG GGAGTACAGA 
CGACGTCACC GTATATCTTC TTTTCGGCCA GTGGAGGATA TCACCGAAGA GGACTTAGAA 
AATGTTGCCA TAACTGTTCG AGATAAAATC TATGATAAAG TTCTGGGTAA CACGTGCCAT 
CAGTGTCGAC AAAAGACCAT CGACACCAAG ACAGTGTGTC GGAACCAGGG TTGCTGTGGT 
GTGCGAGGAC AGTTCTGTGG ACCATGCCTG CGGAACCGCT ATGGGGAGGA TGTCAGATCG 
GCATTGCTGG ACCCGGATTG GGTGTGTCCC CCCTGTCGTG GGATCTGCAA TTGCAGCTAC 
TGTCGGAAGC GTGACGGCCG CTGTGCCACA GGAATCCTCA TTCATCTGGC CAAGTTTTAT 
GGTTATGACA ATGTTAAGGA ATATCTGGAG AGCTTACAAA AGGAGCTGGT AGAAGACAAT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDCA7L ( NM_001127371.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001120843.1 Homo sapiens cell division cycle associated 7 like (CDCA7L), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu06713
Clone ID Related Accession (Same CDS sequence)	NM_001127371.3 , NM_001127371.2
Accession Version	NM_001127371.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1227bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-02
Organism	Homo sapiens(human)
Product	cell division cycle-associated 7-like protein isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC331792.1, BX422040.2, AK300781.1, AL576822.3, AA922229.1, AK022955.1 and BU753973.1. On Jun 2, 2019 this sequence version replaced NM_001127371.2. Transcript Variant: This variant (3) lacks an alternate in-frame coding exon, compared to variant 1. The resulting protein (isoform 3) is shorter when it is compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.215235.1, SRR1660809.23652.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGGAGTTGG CGACTCGCTA CCAGATCCCT AAAGAAGTGG CTGACATCTT TAACGCCCCC 
AGTGATGATG AAGAGTTTGT TGGCTTCCGA GATGATGTTC CCATGGAAAC CCTCTCGTCA 
GAGGAGAGCT GCGATAGTTT TGACTCACTA GAGTCAGGGA AACAGGTCGT GGAGTCAGAT 
TTGAGTGATG ATGGCAAAGC ATCTTTGGTG AGCGAGGAAG AGGAAGATGA AGAAGAAGAT 
AAGGCTACCC CTAGAAGAAG CAGGTCTAGA AGAAGTAGTA TTGGTCTTCG AGTAGCCTTT 
CAGTTCCCCA CCAAGAAGCT GGCCAACAAA CCAGATAAAA ACAGTTCTTC CGAGCAGTTG 
TTTTCTAGCG CACGCTTACA GAATGAGAAA AAAACAATTC TTGAAAGAAA GAAAGACTGT 
AGACAGGTGA TACAAAGGGA AGATTCTACC TCTGAGTCTG AGGATGACTC TCGGGATGAG 
AGCCAGGAGA GTTCAGATGC TTTGCTGAAA AGGACCATGA ACATCAAGGA GAACAAAGCC 
ATGCTTGCCC AGTTATTGGC GGAATTGAAC TCGATGCCAG ATTTCTTCCC AGTACGAACC 
CCAACCTCAG CTTCTAGGAA GAAGACAGTG AGGCGGGCCT TCTCGGAGGG ACAGATCACG 
CGGCGTATGA ACCCAACCCG GAGTGCGCGG CCTCCTGAGA AGTTTGCTCT AGAGAACTTC 
ACTGTCTCAG CCGCTAAATT TGCGGAAGAG TTTTACAGCT TCCGAAGAAG GAAGACAATT 
GGGGGGAAAT GCCGGGAGTA CAGACGACGT CACCGTATAT CTTCTTTTCG GCCAGTGGAG 
GATATCACCG AAGAGGACTT AGAAAATGTT GCCATAACTG TTCGAGATAA AATCTATGAT 
AAAGTTCTGG GTAACACGTG CCATCAGTGT CGACAAAAGA CCATCGACAC CAAGACAGTG 
TGTCGGAACC AGGGTTGCTG TGGTGTGCGA GGACAGTTCT GTGGACCATG CCTGCGGAAC 
CGCTATGGGG AGGATGTCAG ATCGGCATTG CTGGACCCGG ATTGGGTGTG TCCCCCCTGT 
CGTGGGATCT GCAATTGCAG CTACTGTCGG AAGCGTGACG GCCGCTGTGC CACAGGAATC 
CTCATTCATC TGGCCAAGTT TTATGGTTAT GACAATGTTA AGGAATATCT GGAGAGCTTA 
CAAAAGGAGC TGGTAGAAGA CAATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001120843.1
CDS	96..1322
Translation	MELATRYQIPKEVADIFNAPSDDEEFVGFRDDVPMETLSSEESCDSFDSLESGKQVVESDLSDDGKASLVSEEEEDEEEDKATPRRSRSRRSSIGLRVAFQFPTKKLANKPDKNSSSEQLFSSARLQNEKKTILERKKDCRQVIQREDSTSESEDDSRDESQESSDALLKRTMNIKENKAMLAQLLAELNSMPDFFPVRTPTSASRKKTVRRAFSEGQITRRMNPTRSARPPEKFALENFTVSAAKFAEEFYSFRRRKTIGGKCREYRRRHRISSFRPVEDITEEDLENVAITVRDKIYDKVLGNTCHQCRQKTIDTKTVCRNQGCCGVRGQFCGPCLRNRYGEDVRSALLDPDWVCPPCRGICNCSYCRKRDGRCATGILIHLAKFYGYDNVKEYLESLQKELVEDN

Target ORF information:

RefSeq Version	NM_001127371.3
Organism	Homo sapiens(human)
Definition	Homo sapiens cell division cycle associated 7 like (CDCA7L), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001127371.3

ORF Insert Sequence:

ATGGAGTTGG CGACTCGCTA CCAGATCCCT AAAGAAGTGG CTGACATCTT TAACGCCCCC 
AGTGATGATG AAGAGTTTGT TGGCTTCCGA GATGATGTTC CCATGGAAAC CCTCTCGTCA 
GAGGAGAGCT GCGATAGTTT TGACTCACTA GAGTCAGGGA AACAGGTCGT GGAGTCAGAT 
TTGAGTGATG ATGGCAAAGC ATCTTTGGTG AGCGAGGAAG AGGAAGATGA AGAAGAAGAT 
AAGGCTACCC CTAGAAGAAG CAGGTCTAGA AGAAGTAGTA TTGGTCTTCG AGTAGCCTTT 
CAGTTCCCCA CCAAGAAGCT GGCCAACAAA CCAGATAAAA ACAGTTCTTC CGAGCAGTTG 
TTTTCTAGCG CACGCTTACA GAATGAGAAA AAAACAATTC TTGAAAGAAA GAAAGACTGT 
AGACAGGTGA TACAAAGGGA AGATTCTACC TCTGAGTCTG AGGATGACTC TCGGGATGAG 
AGCCAGGAGA GTTCAGATGC TTTGCTGAAA AGGACCATGA ACATCAAGGA GAACAAAGCC 
ATGCTTGCCC AGTTATTGGC GGAATTGAAC TCGATGCCAG ATTTCTTCCC AGTACGAACC 
CCAACCTCAG CTTCTAGGAA GAAGACAGTG AGGCGGGCCT TCTCGGAGGG ACAGATCACG 
CGGCGTATGA ACCCAACCCG GAGTGCGCGG CCTCCTGAGA AGTTTGCTCT AGAGAACTTC 
ACTGTCTCAG CCGCTAAATT TGCGGAAGAG TTTTACAGCT TCCGAAGAAG GAAGACAATT 
GGGGGGAAAT GCCGGGAGTA CAGACGACGT CACCGTATAT CTTCTTTTCG GCCAGTGGAG 
GATATCACCG AAGAGGACTT AGAAAATGTT GCCATAACTG TTCGAGATAA AATCTATGAT 
AAAGTTCTGG GTAACACGTG CCATCAGTGT CGACAAAAGA CCATCGACAC CAAGACAGTG 
TGTCGGAACC AGGGTTGCTG TGGTGTGCGA GGACAGTTCT GTGGACCATG CCTGCGGAAC 
CGCTATGGGG AGGATGTCAG ATCGGCATTG CTGGACCCGG ATTGGGTGTG TCCCCCCTGT 
CGTGGGATCT GCAATTGCAG CTACTGTCGG AAGCGTGACG GCCGCTGTGC CACAGGAATC 
CTCATTCATC TGGCCAAGTT TTATGGTTAT GACAATGTTA AGGAATATCT GGAGAGCTTA 
CAAAAGGAGC TGGTAGAAGA CAATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDCA7L ( NM_001127371.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001120843.1 Homo sapiens cell division cycle associated 7 like (CDCA7L), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu06713
Clone ID Related Accession (Same CDS sequence)	NM_001127371.3 , NM_001127371.2
Accession Version	NM_001127371.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1227bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-09
Organism	Homo sapiens(human)
Product	cell division cycle-associated 7-like protein isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC331792.1, BX422040.2, AK300781.1, AL576822.3, AA922229.1, AK022955.1 and BU753973.1. On Apr 4, 2009 this sequence version replaced NM_001127371.1. Transcript Variant: This variant (3) lacks an alternate in-frame coding exon, compared to variant 1. The resulting protein (isoform 3) is shorter when it is compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.16446.1, SRR1803611.39807.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGGAGTTGG CGACTCGCTA CCAGATCCCT AAAGAAGTGG CTGACATCTT TAACGCCCCC 
AGTGATGATG AAGAGTTTGT TGGCTTCCGA GATGATGTTC CCATGGAAAC CCTCTCGTCA 
GAGGAGAGCT GCGATAGTTT TGACTCACTA GAGTCAGGGA AACAGGTCGT GGAGTCAGAT 
TTGAGTGATG ATGGCAAAGC ATCTTTGGTG AGCGAGGAAG AGGAAGATGA AGAAGAAGAT 
AAGGCTACCC CTAGAAGAAG CAGGTCTAGA AGAAGTAGTA TTGGTCTTCG AGTAGCCTTT 
CAGTTCCCCA CCAAGAAGCT GGCCAACAAA CCAGATAAAA ACAGTTCTTC CGAGCAGTTG 
TTTTCTAGCG CACGCTTACA GAATGAGAAA AAAACAATTC TTGAAAGAAA GAAAGACTGT 
AGACAGGTGA TACAAAGGGA AGATTCTACC TCTGAGTCTG AGGATGACTC TCGGGATGAG 
AGCCAGGAGA GTTCAGATGC TTTGCTGAAA AGGACCATGA ACATCAAGGA GAACAAAGCC 
ATGCTTGCCC AGTTATTGGC GGAATTGAAC TCGATGCCAG ATTTCTTCCC AGTACGAACC 
CCAACCTCAG CTTCTAGGAA GAAGACAGTG AGGCGGGCCT TCTCGGAGGG ACAGATCACG 
CGGCGTATGA ACCCAACCCG GAGTGCGCGG CCTCCTGAGA AGTTTGCTCT AGAGAACTTC 
ACTGTCTCAG CCGCTAAATT TGCGGAAGAG TTTTACAGCT TCCGAAGAAG GAAGACAATT 
GGGGGGAAAT GCCGGGAGTA CAGACGACGT CACCGTATAT CTTCTTTTCG GCCAGTGGAG 
GATATCACCG AAGAGGACTT AGAAAATGTT GCCATAACTG TTCGAGATAA AATCTATGAT 
AAAGTTCTGG GTAACACGTG CCATCAGTGT CGACAAAAGA CCATCGACAC CAAGACAGTG 
TGTCGGAACC AGGGTTGCTG TGGTGTGCGA GGACAGTTCT GTGGACCATG CCTGCGGAAC 
CGCTATGGGG AGGATGTCAG ATCGGCATTG CTGGACCCGG ATTGGGTGTG TCCCCCCTGT 
CGTGGGATCT GCAATTGCAG CTACTGTCGG AAGCGTGACG GCCGCTGTGC CACAGGAATC 
CTCATTCATC TGGCCAAGTT TTATGGTTAT GACAATGTTA AGGAATATCT GGAGAGCTTA 
CAAAAGGAGC TGGTAGAAGA CAATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001120843.1
CDS	121..1347
Translation	MELATRYQIPKEVADIFNAPSDDEEFVGFRDDVPMETLSSEESCDSFDSLESGKQVVESDLSDDGKASLVSEEEEDEEEDKATPRRSRSRRSSIGLRVAFQFPTKKLANKPDKNSSSEQLFSSARLQNEKKTILERKKDCRQVIQREDSTSESEDDSRDESQESSDALLKRTMNIKENKAMLAQLLAELNSMPDFFPVRTPTSASRKKTVRRAFSEGQITRRMNPTRSARPPEKFALENFTVSAAKFAEEFYSFRRRKTIGGKCREYRRRHRISSFRPVEDITEEDLENVAITVRDKIYDKVLGNTCHQCRQKTIDTKTVCRNQGCCGVRGQFCGPCLRNRYGEDVRSALLDPDWVCPPCRGICNCSYCRKRDGRCATGILIHLAKFYGYDNVKEYLESLQKELVEDN

Target ORF information:

RefSeq Version	NM_001127371.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cell division cycle associated 7 like (CDCA7L), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001127371.2

ORF Insert Sequence:

ATGGAGTTGG CGACTCGCTA CCAGATCCCT AAAGAAGTGG CTGACATCTT TAACGCCCCC 
AGTGATGATG AAGAGTTTGT TGGCTTCCGA GATGATGTTC CCATGGAAAC CCTCTCGTCA 
GAGGAGAGCT GCGATAGTTT TGACTCACTA GAGTCAGGGA AACAGGTCGT GGAGTCAGAT 
TTGAGTGATG ATGGCAAAGC ATCTTTGGTG AGCGAGGAAG AGGAAGATGA AGAAGAAGAT 
AAGGCTACCC CTAGAAGAAG CAGGTCTAGA AGAAGTAGTA TTGGTCTTCG AGTAGCCTTT 
CAGTTCCCCA CCAAGAAGCT GGCCAACAAA CCAGATAAAA ACAGTTCTTC CGAGCAGTTG 
TTTTCTAGCG CACGCTTACA GAATGAGAAA AAAACAATTC TTGAAAGAAA GAAAGACTGT 
AGACAGGTGA TACAAAGGGA AGATTCTACC TCTGAGTCTG AGGATGACTC TCGGGATGAG 
AGCCAGGAGA GTTCAGATGC TTTGCTGAAA AGGACCATGA ACATCAAGGA GAACAAAGCC 
ATGCTTGCCC AGTTATTGGC GGAATTGAAC TCGATGCCAG ATTTCTTCCC AGTACGAACC 
CCAACCTCAG CTTCTAGGAA GAAGACAGTG AGGCGGGCCT TCTCGGAGGG ACAGATCACG 
CGGCGTATGA ACCCAACCCG GAGTGCGCGG CCTCCTGAGA AGTTTGCTCT AGAGAACTTC 
ACTGTCTCAG CCGCTAAATT TGCGGAAGAG TTTTACAGCT TCCGAAGAAG GAAGACAATT 
GGGGGGAAAT GCCGGGAGTA CAGACGACGT CACCGTATAT CTTCTTTTCG GCCAGTGGAG 
GATATCACCG AAGAGGACTT AGAAAATGTT GCCATAACTG TTCGAGATAA AATCTATGAT 
AAAGTTCTGG GTAACACGTG CCATCAGTGT CGACAAAAGA CCATCGACAC CAAGACAGTG 
TGTCGGAACC AGGGTTGCTG TGGTGTGCGA GGACAGTTCT GTGGACCATG CCTGCGGAAC 
CGCTATGGGG AGGATGTCAG ATCGGCATTG CTGGACCCGG ATTGGGTGTG TCCCCCCTGT 
CGTGGGATCT GCAATTGCAG CTACTGTCGG AAGCGTGACG GCCGCTGTGC CACAGGAATC 
CTCATTCATC TGGCCAAGTT TTATGGTTAT GACAATGTTA AGGAATATCT GGAGAGCTTA 
CAAAAGGAGC TGGTAGAAGA CAATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Multiple myeloma risk variant at 7p15.3 creates an IRF4-binding site and interferes with CDCA7L expression.
Nature communications713656(2016 Nov)
Li N,Johnson DC,Weinhold N,Studd JB,Orlando G,Mirabella F,Mitchell JS,Meissner T,Kaiser M,Goldschmidt H,Hemminki K,Morgan GJ,Houlston RS

JPO2/CDCA7L and LEDGF/p75 Are Novel Mediators of PI3K/AKT Signaling and Aggressive Phenotypes in Medulloblastoma.
Cancer research76(9)2802-12(2016 05)
Chan TS,Hawkins C,Krieger JR,McGlade CJ,Huang A

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Cell164(4)805-17(2016 Feb)
Yang X,Coulombe-Huntington J,Kang S,Sheynkman GM,Hao T,Richardson A,Sun S,Yang F,Shen YA,Murray RR,Spirohn K,Begg BE,Duran-Frigola M,MacWilliams A,Pevzner SJ,Zhong Q,Trigg SA,Tam S,Ghamsari L,Sahni N,Yi S,Rodriguez MD,Balcha D,Tan G,Costanzo M,Andrews B,Boone C,Zhou XJ,Salehi-Ashtiani K,Charloteaux B,Chen AA,Calderwood MA,Aloy P,Roth FP,Hill DE,Iakoucheva LM,Xia Y,Vidal M

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CDCA7L cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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