| Gene Symbol | GP6 |
| Entrez Gene ID | 51206 |
| Full Name | glycoprotein VI platelet |
| Synonyms | BDPLT11,GPIV,GPVI |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Summary | This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]. |
| Disorder MIM: | |
| Disorder Html: | Bleeding disorder, platelet-type, 11, 614201 (3) |









































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