NDUFA7 cDNA ORF clone, Homo sapiens(Human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NDUFA7
Entrez Gene ID	4701
Full Name	NADH:ubiquinone oxidoreductase subunit A7
Synonyms	B14.5a,CI-B14.5a
General protein information	Preferred Names NADH:ubiquinone oxidoreductase subunit A7 Names NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa NADH-ubiquinone oxidoreductase subunit B14.5a complex I B14.5a subunit
Gene Type	protein-coding
Organism	Homo sapiens(Human)
Genome	Chromosome: 19 Map Location: 19p13.2
Summary	This gene encodes a subunit of NADH:ubiquinone oxidoreductase (complex I), which is a multiprotein complex located in the inner mitochondrial membrane. Complex I functions in the transfer of electrons from NADH to the respiratory chain. [provided by RefSeq, Mar 2011].
Disorder MIM:	602139

mRNA and Protein(s)

mRNA	Protein	Name
NM_005001.4	NP_004992.2	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7
NM_005001.5	NP_004992.2	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7
NM_005001.3	NP_004992.2	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	NDUFA7	XP_533926.1
Gallus gallus (chicken)	NDUFA7	XP_004948729.1
Xenopus tropicalis (tropical clawed frog)	ndufa7	XP_004911066.1
Bos taurus (cattle)	NDUFA7	NP_788831.1
Pan troglodytes (chimpanzee)	NDUFA7	NP_001073395.1
Danio rerio (zebrafish)	ndufa7	NP_001003436.1
Homo sapiens (human)	NDUFA7	NP_004992.2
	LOC711212	XP_002801102.1
Mus musculus (house mouse)	Ndufa7	NP_075691.1
Rattus norvegicus (Norway rat)	Ndufa7	NP_001100242.2

Gene Ontology
Bibliography

Related articles in PubMed

Accessory subunits are integral for assembly and function of human mitochondrial complex I.
Stroud DA, Surgenor EE, Formosa LE, Reljic B, Frazier AE, Dibley MG, Osellame LD, Stait T, Beilharz TH, Thorburn DR, Salim A, Ryan MT
Nature538(7623)123-126(2016 Oct)

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ
PloS one5(9)e12862(2010 Sep)

Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.
Saito A, Kawamoto M, Kamatani N
Journal of human genetics54(6)317-23(2009 Jun)

Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey.
Starr JM, Shiels PG, Harris SE, Pattie A, Pearce MS, Relton CL, Deary IJ
Mechanisms of ageing and development129(12)745-51(2008 Dec)

A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition.
Harris SE, Fox H, Wright AF, Hayward C, Starr JM, Whalley LJ, Deary IJ
BMC genetics843(2007 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association. (HuGE Navigator)
Title: Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

Observational study of gene-disease association. (HuGE Navigator)
Title: Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.

Observational study of gene-disease association. (HuGE Navigator)
Title: Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey.

Observational study of gene-disease association. (HuGE Navigator)
Title: A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition.

The following NDUFA7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NDUFA7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18537	NM_005001.5 Latest version!	Homo sapiens NADH:ubiquinone oxidoreductase subunit A7 (NDUFA7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu18537	NM_005001.4	Homo sapiens NADH:ubiquinone oxidoreductase subunit A7 (NDUFA7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu18537	NM_005001.3	Homo sapiens NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa (NDUFA7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NDUFA7 ( NM_005001.4 ) cDNA ORF clone, Homo sapiens(Human) -> NP_004992.2 Homo sapiens NADH:ubiquinone oxidoreductase subunit A7 (NDUFA7), mRNA.

Price & Availability↑

CloneID	OHu18537
Clone ID Related Accession (Same CDS sequence)	NM_005001.4 , NM_005001.5 , NM_005001.3
Accession Version	NM_005001.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 342bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-24
Organism	Homo sapiens(human)
Product	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC010323.8 and BC003102.1. This sequence is a reference standard in the RefSeqGene project. On Mar 18, 2016 this sequence version replaced NM_005001.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC003102.1, SRR1163657.317376.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968540, SAMEA1970526 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGTCCG CCACCCGTCT CATCCAGCGG CTGCGGAACT GGGCGTCCGG GCATGACCTG 
CAGGGGAAGC TGCAGCTACG CTACCAGGAG ATCTCCAAGC GAACTCAGCC TCCTCCCAAG 
CTCCCTGTGG GTCCTAGCCA CAAGCTCTCC AACAATTACT ATTGCACTCG CGATGGCCGC 
CGGGAATCTG TGCCCCCTTC CATCATCATG TCGTCGCAGA AGGCGCTGGT GTCAGGCAAG 
CCAGCAGAGA GCTCTGCTGT AGCTGCCACT GAGAAGAAGG CGGTGACTCC AGCTCCTCCC 
ATAAAGAGGT GGGAGCTGTC CTCGGACCAG CCTTACCTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004992.2
CDS	56..397
Translation	MASATRLIQRLRNWASGHDLQGKLQLRYQEISKRTQPPPKLPVGPSHKLSNNYYCTRDGRRESVPPSIIMSSQKALVSGKPAESSAVAATEKKAVTPAPPIKRWELSSDQPYL

Target ORF information:

RefSeq Version	NM_005001.4
Organism	Homo sapiens(human)
Definition	Homo sapiens NADH:ubiquinone oxidoreductase subunit A7 (NDUFA7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005001.4

ORF Insert Sequence:

ATGGCGTCCG CCACCCGTCT CATCCAGCGG CTGCGGAACT GGGCGTCCGG GCATGACCTG 
CAGGGGAAGC TGCAGCTACG CTACCAGGAG ATCTCCAAGC GAACTCAGCC TCCTCCCAAG 
CTCCCTGTGG GTCCTAGCCA CAAGCTCTCC AACAATTACT ATTGCACTCG CGATGGCCGC 
CGGGAATCTG TGCCCCCTTC CATCATCATG TCGTCGCAGA AGGCGCTGGT GTCAGGCAAG 
CCAGCAGAGA GCTCTGCTGT AGCTGCCACT GAGAAGAAGG CGGTGACTCC AGCTCCTCCC 
ATAAAGAGGT GGGAGCTGTC CTCGGACCAG CCTTACCTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NDUFA7 ( NM_005001.5 ) cDNA ORF clone, Homo sapiens(Human) -> NP_004992.2 Homo sapiens NADH:ubiquinone oxidoreductase subunit A7 (NDUFA7), mRNA.

Price & Availability↑

CloneID	OHu18537
Clone ID Related Accession (Same CDS sequence)	NM_005001.4 , NM_005001.5 , NM_005001.3
Accession Version	NM_005001.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 342bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC003102.1 and AC010323.8. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_005001.4. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DA189271.1, DA017636.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968540, SAMEA1970526 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta MANE Ensembl match :: ENST00000301457.3/ ENSP00000301457.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGTCCG CCACCCGTCT CATCCAGCGG CTGCGGAACT GGGCGTCCGG GCATGACCTG 
CAGGGGAAGC TGCAGCTACG CTACCAGGAG ATCTCCAAGC GAACTCAGCC TCCTCCCAAG 
CTCCCTGTGG GTCCTAGCCA CAAGCTCTCC AACAATTACT ATTGCACTCG CGATGGCCGC 
CGGGAATCTG TGCCCCCTTC CATCATCATG TCGTCGCAGA AGGCGCTGGT GTCAGGCAAG 
CCAGCAGAGA GCTCTGCTGT AGCTGCCACT GAGAAGAAGG CGGTGACTCC AGCTCCTCCC 
ATAAAGAGGT GGGAGCTGTC CTCGGACCAG CCTTACCTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004992.2
CDS	18..359
Translation	MASATRLIQRLRNWASGHDLQGKLQLRYQEISKRTQPPPKLPVGPSHKLSNNYYCTRDGRRESVPPSIIMSSQKALVSGKPAESSAVAATEKKAVTPAPPIKRWELSSDQPYL

Target ORF information:

RefSeq Version	NM_005001.5
Organism	Homo sapiens(human)
Definition	Homo sapiens NADH:ubiquinone oxidoreductase subunit A7 (NDUFA7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005001.5

ORF Insert Sequence:

ATGGCGTCCG CCACCCGTCT CATCCAGCGG CTGCGGAACT GGGCGTCCGG GCATGACCTG 
CAGGGGAAGC TGCAGCTACG CTACCAGGAG ATCTCCAAGC GAACTCAGCC TCCTCCCAAG 
CTCCCTGTGG GTCCTAGCCA CAAGCTCTCC AACAATTACT ATTGCACTCG CGATGGCCGC 
CGGGAATCTG TGCCCCCTTC CATCATCATG TCGTCGCAGA AGGCGCTGGT GTCAGGCAAG 
CCAGCAGAGA GCTCTGCTGT AGCTGCCACT GAGAAGAAGG CGGTGACTCC AGCTCCTCCC 
ATAAAGAGGT GGGAGCTGTC CTCGGACCAG CCTTACCTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NDUFA7 ( NM_005001.3 ) cDNA ORF clone, Homo sapiens(Human) -> NP_004992.2 Homo sapiens NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa (NDUFA7), mRNA.

Price & Availability↑

CloneID	OHu18537
Clone ID Related Accession (Same CDS sequence)	NM_005001.4 , NM_005001.5 , NM_005001.3
Accession Version	NM_005001.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 342bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7
Comment

ATGGCGTCCG CCACCCGTCT CATCCAGCGG CTGCGGAACT GGGCGTCCGG GCATGACCTG 
CAGGGGAAGC TGCAGCTACG CTACCAGGAG ATCTCCAAGC GAACTCAGCC TCCTCCCAAG 
CTCCCTGTGG GTCCTAGCCA CAAGCTCTCC AACAATTACT ATTGCACTCG CGATGGCCGC 
CGGGAATCTG TGCCCCCTTC CATCATCATG TCGTCGCAGA AGGCGCTGGT GTCAGGCAAG 
CCAGCAGAGA GCTCTGCTGT AGCTGCCACT GAGAAGAAGG CGGTGACTCC AGCTCCTCCC 
ATAAAGAGGT GGGAGCTGTC CTCGGACCAG CCTTACCTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004992.2
Translation	MASATRLIQRLRNWASGHDLQGKLQLRYQEISKRTQPPPKLPVGPSHKLSNNYYCTRDGRRESVPPSIIMSSQKALVSGKPAESSAVAATEKKAVTPAPPIKRWELSSDQPYL

Target ORF information:

RefSeq Version	NM_005001.3
Organism	Homo sapiens(Human)
Definition	Homo sapiens NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa (NDUFA7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005001.3

ORF Insert Sequence:

ATGGCGTCCG CCACCCGTCT CATCCAGCGG CTGCGGAACT GGGCGTCCGG GCATGACCTG 
CAGGGGAAGC TGCAGCTACG CTACCAGGAG ATCTCCAAGC GAACTCAGCC TCCTCCCAAG 
CTCCCTGTGG GTCCTAGCCA CAAGCTCTCC AACAATTACT ATTGCACTCG CGATGGCCGC 
CGGGAATCTG TGCCCCCTTC CATCATCATG TCGTCGCAGA AGGCGCTGGT GTCAGGCAAG 
CCAGCAGAGA GCTCTGCTGT AGCTGCCACT GAGAAGAAGG CGGTGACTCC AGCTCCTCCC 
ATAAAGAGGT GGGAGCTGTC CTCGGACCAG CCTTACCTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Accessory subunits are integral for assembly and function of human mitochondrial complex I.
Nature538(7623)123-126(2016 Oct)
Stroud DA,Surgenor EE,Formosa LE,Reljic B,Frazier AE,Dibley MG,Osellame LD,Stait T,Beilharz TH,Thorburn DR,Salim A,Ryan MT

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
PloS one5(9)e12862(2010 Sep)
Hendrickson SL,Lautenberger JA,Chinn LW,Malasky M,Sezgin E,Kingsley LA,Goedert JJ,Kirk GD,Gomperts ED,Buchbinder SP,Troyer JL,O'Brien SJ

Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.
Journal of human genetics54(6)317-23(2009 Jun)
Saito A,Kawamoto M,Kamatani N

Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey.
Mechanisms of ageing and development129(12)745-51(2008 Dec)
Starr JM,Shiels PG,Harris SE,Pattie A,Pearce MS,Relton CL,Deary IJ

A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition.
BMC genetics843(2007 Jul)
Harris SE,Fox H,Wright AF,Hayward C,Starr JM,Whalley LJ,Deary IJ