The following SIGLEC16 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SIGLEC16 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OHu102337 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_001348364.1 | |
| Accession Version | NM_001348364.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1482bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-09-09 | |
| Organism | Homo sapiens(human) | |
| Product | sialic acid-binding Ig-like lectin 16 precursor | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK301031.1, BC030222.1 and AC011452.6. Transcript Variant: This variant (1) represents the functional allele encoding the full-length protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK301031.1, BC039008.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142670, SAMEA2145245 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## polymorphic pseudogene :: PMID: 18629938, 22383531 ##RefSeq-Attributes-END## | |
1 | ATGGTCCCGG GACAGGCCCA GCCCCAGAGC CCAGAGATGC TGCTGCTGCC CCTGCTGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001335293.1 |
| CDS | 67..1548 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001348364.1 |
1 | ATGGTCCCGG GACAGGCCCA GCCCCAGAGC CCAGAGATGC TGCTGCTGCC CCTGCTGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu107133 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001348364.2 | |
| Accession Version | NM_001348364.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1446bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-07-05 | |
| Organism | Homo sapiens(human) | |
| Product | sialic acid-binding Ig-like lectin 16 precursor | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK301031.1, BC030222.1 and AC011452.6. On Nov 3, 2018 this sequence version replaced NM_001348364.1. Transcript Variant: This variant (1) represents the functional allele encoding the full-length protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: EU330985.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142670, SAMEA2145245 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved polymorphic pseudogene :: PMID: 18629938, 22383531 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## | |
1 | ATGCTGCTGC TGCCCCTGCT GCTGCCCGTG CTGGGGGCGG GGTCCCTGAA CAAGGATCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001335293.2 |
| CDS | 39..1484 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001348364.2 |
1 | ATGCTGCTGC TGCCCCTGCT GCTGCCCGTG CTGGGGGCGG GGTCCCTGAA CAAGGATCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Paired Siglec receptors generate opposite inflammatory responses to a human-specific pathogen. |
Evolution of siglec-11 and siglec-16 genes in hominins. |
SIGLEC16 encodes a DAP12-associated receptor expressed in macrophages that evolved from its inhibitory counterpart SIGLEC11 and has functional and non-functional alleles in humans. |
A human-specific gene in microglia. |
The DNA sequence and biology of human chromosome 19. |
