FOXK2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	FOXK2
Entrez Gene ID	3607
Full Name	forkhead box K2
Synonyms	ILF,ILF-1,ILF1
General protein information	Preferred Names forkhead box K2 Names forkhead box protein K2 FOXK1 cellular transcription factor ILF-1 interleukin enhancer-binding factor 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q25.3
Summary	The protein encoded by this gene contains a fork head DNA binding domain. This protein can bind to the purine-rich motifs of the HIV long terminal repeat (LTR), and to the similar purine-rich motif in the interleukin 2 (IL2) promoter. It may be involved in the regulation of viral and cellular promoter elements. [provided by RefSeq, Jul 2008].
Disorder MIM:	147685

mRNA and Protein(s)

mRNA	Protein	Name
XM_024450739.1	XP_024306507.1	forkhead box protein K2 isoform X1
NM_004514.3	NP_004505.2	forkhead box protein K2
NM_004514.4	NP_004505.2	forkhead box protein K2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	FOXK2	XP_003315834.1
Xenopus tropicalis (tropical clawed frog)	foxk2	NP_001135634.1
Mus musculus (house mouse)	Foxk2	NP_001074401.2
Gallus gallus (chicken)	FOXK2	XP_425369.4
	FOXK2	XP_001114082.2
Canis lupus familiaris (dog)	FOXK2	XP_005642232.1
Danio rerio (zebrafish)	si:ch211-262e15.1	XP_001922856.1
Homo sapiens (human)	FOXK2	NP_004505.2
Bos taurus (cattle)	FOXK2	XP_002696174.3

Gene Ontology
Bibliography

Related articles in PubMed

FOXK2, regulted by miR-1271-5p, promotes cell growth and indicates unfavorable prognosis in hepatocellular carcinoma.
Lin MF, Yang YF, Peng ZP, Zhang MF, Liang JY, Chen W, Liu XH, Zheng YL
The international journal of biochemistry & cell biology88155-161(2017 07)

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

FOXK2, regulted by miR-1271-5p, promotes cell growth and indicates unfavorable prognosis in hepatocellular carcinoma
Title: FOXK2, regulted by miR-1271-5p, promotes cell growth and indicates unfavorable prognosis in hepatocellular carcinoma.

Results show that Foxk2 expression was downregulated in lung adenocarcinoma tissues and non-small cell lung cancer cell (NSCLC) lines. Its overexpression suppresses epithelial-mesenchymal transition in NSCLC cells and inhibits cell migration and invasion. Also, the expression of Foxk2 seems to be regulated by miR-1271.
Title: Foxk2 inhibits non-small cell lung cancer epithelial-mesenchymal transition and proliferation through the repression of different key target genes.

SOX9 transcriptionally activated FOXK2 was involved in the pathogenesis of colorectal cancer.FOXK2 is highly expressed in colorectal cancer tissues.
Title: Sox9 mediated transcriptional activation of FOXK2 is critical for colorectal cancer cells proliferation.

FOXO3-dependent gene regulation is generally mediated not through uniquely bound regions but through regions occupied by both FOXK2 and FOXO3 where both factors play a regulatory role.
Title: Genome-wide binding studies reveal DNA binding specificity mechanisms and functional interplay amongst Forkhead transcription factors.

FOXK1 and FOXK2 positively regulate Wnt/beta-catenin signaling by translocating dishevelled proteins into the nucleus.
Title: FOXKs promote Wnt/?-catenin signaling by translocating DVL into the nucleus.

The following FOXK2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FOXK2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30465	NM_004514.4 Latest version!	Homo sapiens forkhead box K2 (FOXK2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$274.50-$384.30 $549.00
OHu104397	XM_024450739.1 Latest version!	Homo sapiens forkhead box K2 (FOXK2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OHu30465	NM_004514.3	Homo sapiens forkhead box K2 (FOXK2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$274.50-$384.30 $549.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FOXK2 ( NM_004514.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_004505.2 Homo sapiens forkhead box K2 (FOXK2), mRNA.

Price & Availability↑

CloneID	OHu30465
Clone ID Related Accession (Same CDS sequence)	NM_004514.3 , NM_004514.4
Accession Version	NM_004514.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1983bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-05
Organism	Homo sapiens(human)
Product	forkhead box protein K2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC124287.10, U58196.1 and AC124283.11. On Jun 28, 2006 this sequence version replaced NM_004514.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.107086.1, SRR1803613.198923.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCGG CCGCGGCGGC GCTCTCGGGC GCGGGCACGC CACCCGCGGG CGGCGGGGCC 
GGGGGCGGCG GGGCCGGGGG CGGCGGGTCC CCGCCGGGCG GCTGGGCCGT GGCGCGCCTG 
GAGGGCCGCG AGTTCGAGTA TCTGATGAAG AAGCGCTCGG TGACCATCGG CCGCAACTCG 
TCGCAGGGCT CGGTGGACGT GAGCATGGGC CACTCGAGCT TCATCTCCCG GCGCCACCTC 
GAGATCTTCA CGCCCCCGGG CGGCGGCGGC CATGGCGGGG CCGCTCCGGA GCTGCCGCCC 
GCGCAGCCCA GGCCCGACGC CGGCGGCGAC TTCTACCTGC GCTGCTTGGG CAAGAACGGG 
GTATTCGTGG ACGGCGTGTT CCAGAGGCGC GGGGCGCCGC CGCTGCAGCT GCCGCGCGTG 
TGCACATTCA GGTTCCCGAG CACAAACATC AAGATAACGT TCACTGCCCT GTCCAGCGAG 
AAGAGAGAGA AGCAGGAGGC GTCTGAGTCT CCAGTGAAGG CCGTACAGCC ACACATCTCG 
CCCCTGACCA TCAACATTCC AGACACCATG GCCCACCTCA TCAGCCCTCT GCCCTCCCCC 
ACGGGAACCA TCAGCGCTGC AAACTCCTGC CCCTCCAGCC CCCGGGGAGC GGGGTCTTCA 
GGGTACAAGG TGGGCCGAGT GATGCCATCT GACCTCAATT TAATGGCTGA CAACTCACAG 
CCTGAAAATG AAAAGGAAGC TTCAGGTGGA GACAGCCCGA AGGATGATTC AAAGCCGCCT 
TACTCCTACG CGCAGCTGAT AGTTCAGGCG ATTACGATGG CTCCCGACAA ACAGCTCACC 
CTGAACGGGA TTTATACACA CATCACTAAA AATTATCCCT ACTACAGGAC TGCGGACAAG 
GGCTGGCAGA ATTCAATTCG CCACAATCTC TCTCTGAATC GTTATTTCAT CAAAGTGCCG 
CGTTCCCAGG AAGAACCAGG CAAAGGCTCG TTCTGGAGGA TAGACCCAGC CTCTGAAAGC 
AAATTAATAG AACAGGCTTT TAGGAAACGA CGGCCTAGGG GCGTGCCCTG CTTTAGAACC 
CCTCTGGGAC CGCTCTCTTC TAGGAGTGCC CCAGCCTCTC CCAATCACGC GGGAGTGCTG 
TCTGCTCACT CTAGTGGCGC CCAGACCCCT GAGAGCCTGT CGAGGGAAGG TTCGCCGGCC 
CCCCTGGAGC CTGAGCCTGG CGCTGCACAG CCCAAACTCG CTGTCATCCA GGAAGCCCGG 
TTTGCCCAGA GCGCCCCAGG GTCACCTCTG TCCAGTCAGC CAGTCTTAAT CACCGTCCAG 
CGGCAGCTAC CACAGGCCAT CAAGCCTGTC ACCTACACTG TGGCCACCCC AGTGACCACC 
TCGACCTCCC AGCCACCCGT CGTGCAGACG GTTCACGTCG TCCACCAGAT CCCAGCGGTG 
TCGGTCACCA GTGTGGCCGG ACTGGCCCCA GCGAACACGT ACACTGTCTC TGGACAAGCT 
GTGGTCACCC CGGCAGCCGT GCTGGCCCCT CCTAAGGCAG AGGCCCAGGA GAATGGAGAC 
CACAGGGAAG TCAAAGTGAA AGTAGAGCCT ATTCCCGCCA TTGGCCACGC CACGCTCGGC 
ACTGCCAGCC GGATCATTCA GACGGCACAG ACCACCCCGG TCCAGACGGT GACCATAGTA 
CAACAGGCAC CTCTAGGTCA ACACCAGCTA CCAATAAAAA CTGTAACACA AAACGGCACT 
CACGTGGCAT CAGTCCCCAC TGCGGTCCAC GGCCAGGTGA ACAATGCCGC GGCGAGTCCT 
TTGCACATGT TGGCAACACA CGCATCCGCA TCGGCCTCCC TGCCCACAAA GCGCCACAAC 
GGTGACCAGC CGGAGCAGCC GGAGCTGAAG CGGATCAAGA CAGAAGACGG CGAGGGCATC 
GTCATTGCCC TGAGCGTGGA CACGCCACCG GCAGCCGTAA GGGAAAAGGG TGTCCAGAAC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004505.2
CDS	172..2154
Translation	MAAAAAALSGAGTPPAGGGAGGGGAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSMGHSSFISRRHLEIFTPPGGGGHGGAAPELPPAQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVCTFRFPSTNIKITFTALSSEKREKQEASESPVKAVQPHISPLTINIPDTMAHLISPLPSPTGTISAANSCPSSPRGAGSSGYKVGRVMPSDLNLMADNSQPENEKEASGGDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASESKLIEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHAGVLSAHSSGAQTPESLSREGSPAPLEPEPGAAQPKLAVIQEARFAQSAPGSPLSSQPVLITVQRQLPQAIKPVTYTVATPVTTSTSQPPVVQTVHVVHQIPAVSVTSVAGLAPANTYTVSGQAVVTPAAVLAPPKAEAQENGDHREVKVKVEPIPAIGHATLGTASRIIQTAQTTPVQTVTIVQQAPLGQHQLPIKTVTQNGTHVASVPTAVHGQVNNAAASPLHMLATHASASASLPTKRHNGDQPEQPELKRIKTEDGEGIVIALSVDTPPAAVREKGVQN

Target ORF information:

RefSeq Version	NM_004514.3
Organism	Homo sapiens(human)
Definition	Homo sapiens forkhead box K2 (FOXK2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004514.3

ORF Insert Sequence:

ATGGCGGCGG CCGCGGCGGC GCTCTCGGGC GCGGGCACGC CACCCGCGGG CGGCGGGGCC 
GGGGGCGGCG GGGCCGGGGG CGGCGGGTCC CCGCCGGGCG GCTGGGCCGT GGCGCGCCTG 
GAGGGCCGCG AGTTCGAGTA TCTGATGAAG AAGCGCTCGG TGACCATCGG CCGCAACTCG 
TCGCAGGGCT CGGTGGACGT GAGCATGGGC CACTCGAGCT TCATCTCCCG GCGCCACCTC 
GAGATCTTCA CGCCCCCGGG CGGCGGCGGC CATGGCGGGG CCGCTCCGGA GCTGCCGCCC 
GCGCAGCCCA GGCCCGACGC CGGCGGCGAC TTCTACCTGC GCTGCTTGGG CAAGAACGGG 
GTATTCGTGG ACGGCGTGTT CCAGAGGCGC GGGGCGCCGC CGCTGCAGCT GCCGCGCGTG 
TGCACATTCA GGTTCCCGAG CACAAACATC AAGATAACGT TCACTGCCCT GTCCAGCGAG 
AAGAGAGAGA AGCAGGAGGC GTCTGAGTCT CCAGTGAAGG CCGTACAGCC ACACATCTCG 
CCCCTGACCA TCAACATTCC AGACACCATG GCCCACCTCA TCAGCCCTCT GCCCTCCCCC 
ACGGGAACCA TCAGCGCTGC AAACTCCTGC CCCTCCAGCC CCCGGGGAGC GGGGTCTTCA 
GGGTACAAGG TGGGCCGAGT GATGCCATCT GACCTCAATT TAATGGCTGA CAACTCACAG 
CCTGAAAATG AAAAGGAAGC TTCAGGTGGA GACAGCCCGA AGGATGATTC AAAGCCGCCT 
TACTCCTACG CGCAGCTGAT AGTTCAGGCG ATTACGATGG CTCCCGACAA ACAGCTCACC 
CTGAACGGGA TTTATACACA CATCACTAAA AATTATCCCT ACTACAGGAC TGCGGACAAG 
GGCTGGCAGA ATTCAATTCG CCACAATCTC TCTCTGAATC GTTATTTCAT CAAAGTGCCG 
CGTTCCCAGG AAGAACCAGG CAAAGGCTCG TTCTGGAGGA TAGACCCAGC CTCTGAAAGC 
AAATTAATAG AACAGGCTTT TAGGAAACGA CGGCCTAGGG GCGTGCCCTG CTTTAGAACC 
CCTCTGGGAC CGCTCTCTTC TAGGAGTGCC CCAGCCTCTC CCAATCACGC GGGAGTGCTG 
TCTGCTCACT CTAGTGGCGC CCAGACCCCT GAGAGCCTGT CGAGGGAAGG TTCGCCGGCC 
CCCCTGGAGC CTGAGCCTGG CGCTGCACAG CCCAAACTCG CTGTCATCCA GGAAGCCCGG 
TTTGCCCAGA GCGCCCCAGG GTCACCTCTG TCCAGTCAGC CAGTCTTAAT CACCGTCCAG 
CGGCAGCTAC CACAGGCCAT CAAGCCTGTC ACCTACACTG TGGCCACCCC AGTGACCACC 
TCGACCTCCC AGCCACCCGT CGTGCAGACG GTTCACGTCG TCCACCAGAT CCCAGCGGTG 
TCGGTCACCA GTGTGGCCGG ACTGGCCCCA GCGAACACGT ACACTGTCTC TGGACAAGCT 
GTGGTCACCC CGGCAGCCGT GCTGGCCCCT CCTAAGGCAG AGGCCCAGGA GAATGGAGAC 
CACAGGGAAG TCAAAGTGAA AGTAGAGCCT ATTCCCGCCA TTGGCCACGC CACGCTCGGC 
ACTGCCAGCC GGATCATTCA GACGGCACAG ACCACCCCGG TCCAGACGGT GACCATAGTA 
CAACAGGCAC CTCTAGGTCA ACACCAGCTA CCAATAAAAA CTGTAACACA AAACGGCACT 
CACGTGGCAT CAGTCCCCAC TGCGGTCCAC GGCCAGGTGA ACAATGCCGC GGCGAGTCCT 
TTGCACATGT TGGCAACACA CGCATCCGCA TCGGCCTCCC TGCCCACAAA GCGCCACAAC 
GGTGACCAGC CGGAGCAGCC GGAGCTGAAG CGGATCAAGA CAGAAGACGG CGAGGGCATC 
GTCATTGCCC TGAGCGTGGA CACGCCACCG GCAGCCGTAA GGGAAAAGGG TGTCCAGAAC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FOXK2 ( NM_004514.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_004505.2 Homo sapiens forkhead box K2 (FOXK2), mRNA.

Price & Availability↑

CloneID	OHu30465
Clone ID Related Accession (Same CDS sequence)	NM_004514.3 , NM_004514.4
Accession Version	NM_004514.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1983bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Homo sapiens(human)
Product	forkhead box protein K2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC124287.10, U58196.1 and AC124283.11. On Nov 23, 2018 this sequence version replaced NM_004514.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.107086.1, SRR1803613.198923.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000335255.10/ ENSP00000335677.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGCGG CCGCGGCGGC GCTCTCGGGC GCGGGCACGC CACCCGCGGG CGGCGGGGCC 
GGGGGCGGCG GGGCCGGGGG CGGCGGGTCC CCGCCGGGCG GCTGGGCCGT GGCGCGCCTG 
GAGGGCCGCG AGTTCGAGTA TCTGATGAAG AAGCGCTCGG TGACCATCGG CCGCAACTCG 
TCGCAGGGCT CGGTGGACGT GAGCATGGGC CACTCGAGCT TCATCTCCCG GCGCCACCTC 
GAGATCTTCA CGCCCCCGGG CGGCGGCGGC CATGGCGGGG CCGCTCCGGA GCTGCCGCCC 
GCGCAGCCCA GGCCCGACGC CGGCGGCGAC TTCTACCTGC GCTGCTTGGG CAAGAACGGG 
GTATTCGTGG ACGGCGTGTT CCAGAGGCGC GGGGCGCCGC CGCTGCAGCT GCCGCGCGTG 
TGCACATTCA GGTTCCCGAG CACAAACATC AAGATAACGT TCACTGCCCT GTCCAGCGAG 
AAGAGAGAGA AGCAGGAGGC GTCTGAGTCT CCAGTGAAGG CCGTACAGCC ACACATCTCG 
CCCCTGACCA TCAACATTCC AGACACCATG GCCCACCTCA TCAGCCCTCT GCCCTCCCCC 
ACGGGAACCA TCAGCGCTGC AAACTCCTGC CCCTCCAGCC CCCGGGGAGC GGGGTCTTCA 
GGGTACAAGG TGGGCCGAGT GATGCCATCT GACCTCAATT TAATGGCTGA CAACTCACAG 
CCTGAAAATG AAAAGGAAGC TTCAGGTGGA GACAGCCCGA AGGATGATTC AAAGCCGCCT 
TACTCCTACG CGCAGCTGAT AGTTCAGGCG ATTACGATGG CTCCCGACAA ACAGCTCACC 
CTGAACGGGA TTTATACACA CATCACTAAA AATTATCCCT ACTACAGGAC TGCGGACAAG 
GGCTGGCAGA ATTCAATTCG CCACAATCTC TCTCTGAATC GTTATTTCAT CAAAGTGCCG 
CGTTCCCAGG AAGAACCAGG CAAAGGCTCG TTCTGGAGGA TAGACCCAGC CTCTGAAAGC 
AAATTAATAG AACAGGCTTT TAGGAAACGA CGGCCTAGGG GCGTGCCCTG CTTTAGAACC 
CCTCTGGGAC CGCTCTCTTC TAGGAGTGCC CCAGCCTCTC CCAATCACGC GGGAGTGCTG 
TCTGCTCACT CTAGTGGCGC CCAGACCCCT GAGAGCCTGT CGAGGGAAGG TTCGCCGGCC 
CCCCTGGAGC CTGAGCCTGG CGCTGCACAG CCCAAACTCG CTGTCATCCA GGAAGCCCGG 
TTTGCCCAGA GCGCCCCAGG GTCACCTCTG TCCAGTCAGC CAGTCTTAAT CACCGTCCAG 
CGGCAGCTAC CACAGGCCAT CAAGCCTGTC ACCTACACTG TGGCCACCCC AGTGACCACC 
TCGACCTCCC AGCCACCCGT CGTGCAGACG GTTCACGTCG TCCACCAGAT CCCAGCGGTG 
TCGGTCACCA GTGTGGCCGG ACTGGCCCCA GCGAACACGT ACACTGTCTC TGGACAAGCT 
GTGGTCACCC CGGCAGCCGT GCTGGCCCCT CCTAAGGCAG AGGCCCAGGA GAATGGAGAC 
CACAGGGAAG TCAAAGTGAA AGTAGAGCCT ATTCCCGCCA TTGGCCACGC CACGCTCGGC 
ACTGCCAGCC GGATCATTCA GACGGCACAG ACCACCCCGG TCCAGACGGT GACCATAGTA 
CAACAGGCAC CTCTAGGTCA ACACCAGCTA CCAATAAAAA CTGTAACACA AAACGGCACT 
CACGTGGCAT CAGTCCCCAC TGCGGTCCAC GGCCAGGTGA ACAATGCCGC GGCGAGTCCT 
TTGCACATGT TGGCAACACA CGCATCCGCA TCGGCCTCCC TGCCCACAAA GCGCCACAAC 
GGTGACCAGC CGGAGCAGCC GGAGCTGAAG CGGATCAAGA CAGAAGACGG CGAGGGCATC 
GTCATTGCCC TGAGCGTGGA CACGCCACCG GCAGCCGTAA GGGAAAAGGG TGTCCAGAAC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004505.2
CDS	158..2140
Translation	MAAAAAALSGAGTPPAGGGAGGGGAGGGGSPPGGWAVARLEGREFEYLMKKRSVTIGRNSSQGSVDVSMGHSSFISRRHLEIFTPPGGGGHGGAAPELPPAQPRPDAGGDFYLRCLGKNGVFVDGVFQRRGAPPLQLPRVCTFRFPSTNIKITFTALSSEKREKQEASESPVKAVQPHISPLTINIPDTMAHLISPLPSPTGTISAANSCPSSPRGAGSSGYKVGRVMPSDLNLMADNSQPENEKEASGGDSPKDDSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASESKLIEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHAGVLSAHSSGAQTPESLSREGSPAPLEPEPGAAQPKLAVIQEARFAQSAPGSPLSSQPVLITVQRQLPQAIKPVTYTVATPVTTSTSQPPVVQTVHVVHQIPAVSVTSVAGLAPANTYTVSGQAVVTPAAVLAPPKAEAQENGDHREVKVKVEPIPAIGHATLGTASRIIQTAQTTPVQTVTIVQQAPLGQHQLPIKTVTQNGTHVASVPTAVHGQVNNAAASPLHMLATHASASASLPTKRHNGDQPEQPELKRIKTEDGEGIVIALSVDTPPAAVREKGVQN

Target ORF information:

RefSeq Version	NM_004514.4
Organism	Homo sapiens(human)
Definition	Homo sapiens forkhead box K2 (FOXK2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004514.4

ORF Insert Sequence:

ATGGCGGCGG CCGCGGCGGC GCTCTCGGGC GCGGGCACGC CACCCGCGGG CGGCGGGGCC 
GGGGGCGGCG GGGCCGGGGG CGGCGGGTCC CCGCCGGGCG GCTGGGCCGT GGCGCGCCTG 
GAGGGCCGCG AGTTCGAGTA TCTGATGAAG AAGCGCTCGG TGACCATCGG CCGCAACTCG 
TCGCAGGGCT CGGTGGACGT GAGCATGGGC CACTCGAGCT TCATCTCCCG GCGCCACCTC 
GAGATCTTCA CGCCCCCGGG CGGCGGCGGC CATGGCGGGG CCGCTCCGGA GCTGCCGCCC 
GCGCAGCCCA GGCCCGACGC CGGCGGCGAC TTCTACCTGC GCTGCTTGGG CAAGAACGGG 
GTATTCGTGG ACGGCGTGTT CCAGAGGCGC GGGGCGCCGC CGCTGCAGCT GCCGCGCGTG 
TGCACATTCA GGTTCCCGAG CACAAACATC AAGATAACGT TCACTGCCCT GTCCAGCGAG 
AAGAGAGAGA AGCAGGAGGC GTCTGAGTCT CCAGTGAAGG CCGTACAGCC ACACATCTCG 
CCCCTGACCA TCAACATTCC AGACACCATG GCCCACCTCA TCAGCCCTCT GCCCTCCCCC 
ACGGGAACCA TCAGCGCTGC AAACTCCTGC CCCTCCAGCC CCCGGGGAGC GGGGTCTTCA 
GGGTACAAGG TGGGCCGAGT GATGCCATCT GACCTCAATT TAATGGCTGA CAACTCACAG 
CCTGAAAATG AAAAGGAAGC TTCAGGTGGA GACAGCCCGA AGGATGATTC AAAGCCGCCT 
TACTCCTACG CGCAGCTGAT AGTTCAGGCG ATTACGATGG CTCCCGACAA ACAGCTCACC 
CTGAACGGGA TTTATACACA CATCACTAAA AATTATCCCT ACTACAGGAC TGCGGACAAG 
GGCTGGCAGA ATTCAATTCG CCACAATCTC TCTCTGAATC GTTATTTCAT CAAAGTGCCG 
CGTTCCCAGG AAGAACCAGG CAAAGGCTCG TTCTGGAGGA TAGACCCAGC CTCTGAAAGC 
AAATTAATAG AACAGGCTTT TAGGAAACGA CGGCCTAGGG GCGTGCCCTG CTTTAGAACC 
CCTCTGGGAC CGCTCTCTTC TAGGAGTGCC CCAGCCTCTC CCAATCACGC GGGAGTGCTG 
TCTGCTCACT CTAGTGGCGC CCAGACCCCT GAGAGCCTGT CGAGGGAAGG TTCGCCGGCC 
CCCCTGGAGC CTGAGCCTGG CGCTGCACAG CCCAAACTCG CTGTCATCCA GGAAGCCCGG 
TTTGCCCAGA GCGCCCCAGG GTCACCTCTG TCCAGTCAGC CAGTCTTAAT CACCGTCCAG 
CGGCAGCTAC CACAGGCCAT CAAGCCTGTC ACCTACACTG TGGCCACCCC AGTGACCACC 
TCGACCTCCC AGCCACCCGT CGTGCAGACG GTTCACGTCG TCCACCAGAT CCCAGCGGTG 
TCGGTCACCA GTGTGGCCGG ACTGGCCCCA GCGAACACGT ACACTGTCTC TGGACAAGCT 
GTGGTCACCC CGGCAGCCGT GCTGGCCCCT CCTAAGGCAG AGGCCCAGGA GAATGGAGAC 
CACAGGGAAG TCAAAGTGAA AGTAGAGCCT ATTCCCGCCA TTGGCCACGC CACGCTCGGC 
ACTGCCAGCC GGATCATTCA GACGGCACAG ACCACCCCGG TCCAGACGGT GACCATAGTA 
CAACAGGCAC CTCTAGGTCA ACACCAGCTA CCAATAAAAA CTGTAACACA AAACGGCACT 
CACGTGGCAT CAGTCCCCAC TGCGGTCCAC GGCCAGGTGA ACAATGCCGC GGCGAGTCCT 
TTGCACATGT TGGCAACACA CGCATCCGCA TCGGCCTCCC TGCCCACAAA GCGCCACAAC 
GGTGACCAGC CGGAGCAGCC GGAGCTGAAG CGGATCAAGA CAGAAGACGG CGAGGGCATC 
GTCATTGCCC TGAGCGTGGA CACGCCACCG GCAGCCGTAA GGGAAAAGGG TGTCCAGAAC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FOXK2 ( XM_024450739.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024306507.1 Homo sapiens forkhead box K2 (FOXK2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu104397
Clone ID Related Accession (Same CDS sequence)	XM_024450739.1
Accession Version	XM_024450739.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1167bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	forkhead box protein K2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCCCG ACAAACAGCT CACCCTGAAC GGGATTTATA CACACATCAC TAAAAATTAT 
CCCTACTACA GGACTGCGGA CAAGGGCTGG CAGAATTCAA TTCGCCACAA TCTCTCTCTG 
AATCGTTATT TCATCAAAGT GCCGCGTTCC CAGGAAGAAC CAGGCAAAGG CTCGTTCTGG 
AGGATAGACC CAGCCTCTGA AAGCAAATTA ATAGAACAGG CTTTTAGGAA ACGACGGCCT 
AGGGGCGTGC CCTGCTTTAG AACCCCTCTG GGACCGCTCT CTTCTAGGAG TGCCCCAGCC 
TCTCCCAATC ACGCGGGAGT GCTGTCTGCT CACTCTAGTG GCGCCCAGAC CCCTGAGAGC 
CTGTCGAGGG AAGGTTCGCC GGCCCCCCTG GAGCCTGAGC CTGGCGCTGC ACAGCCCAAA 
CTCGCTGTCA TCCAGGAAGC CCGGTTTGCC CAGAGCGCCC CAGGGTCACC TCTGTCCAGT 
CAGCCAGTCT TAATCACCGT CCAGCGGCAG CTACCACAGG CCATCAAGCC TGTCACCTAC 
ACTGTGGCCA CCCCAGTGAC CACCTCGACC TCCCAGCCAC CCGTCGTGCA GACGGTTCAC 
GTCGTCCACC AGATCCCAGC GGTGTCGGTC ACCAGTGTGG CCGGACTGGC CCCAGCGAAC 
ACGTACACTG TCTCTGGACA AGCTGTGGTC ACCCCGGCAG CCGTGCTGGC CCCTCCTAAG 
GCAGAGGCCC AGGAGAATGG AGACCACAGG GAAGTCAAAG TGAAAGTAGA GCCTATTCCC 
GCCATTGGCC ACGCCACGCT CGGCACTGCC AGCCGGATCA TTCAGACGGC ACAGACCACC 
CCGGTCCAGA CGGTGACCAT AGTACAACAG GCACCTCTAG GTCAACACCA GCTACCAATA 
AAAACTGTAA CACAAAACGG CACTCACGTG GCATCAGTCC CCACTGCGGT CCACGGCCAG 
GTGAACAATG CCGCGGCGAG TCCTTTGCAC ATGTTGGCAA CACACGCATC CGCATCGGCC 
TCCCTGCCCA CAAAGCGCCA CAACGGTGAC CAGCCGGAGC AGCCGGAGCT GAAGCGGATC 
AAGACAGAAG ACGGCGAGGG CATCGTCATT GCCCTGAGCG TGGACACGCC ACCGGCAGCC 
GTAAGGGAAA AGGGTGTCCA GAACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024306507.1
CDS	562..1728
Translation	MAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASESKLIEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHAGVLSAHSSGAQTPESLSREGSPAPLEPEPGAAQPKLAVIQEARFAQSAPGSPLSSQPVLITVQRQLPQAIKPVTYTVATPVTTSTSQPPVVQTVHVVHQIPAVSVTSVAGLAPANTYTVSGQAVVTPAAVLAPPKAEAQENGDHREVKVKVEPIPAIGHATLGTASRIIQTAQTTPVQTVTIVQQAPLGQHQLPIKTVTQNGTHVASVPTAVHGQVNNAAASPLHMLATHASASASLPTKRHNGDQPEQPELKRIKTEDGEGIVIALSVDTPPAAVREKGVQN

Target ORF information:

RefSeq Version	XM_024450739.1
Organism	Homo sapiens(human)
Definition	Homo sapiens forkhead box K2 (FOXK2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024450739.1

ORF Insert Sequence:

ATGGCTCCCG ACAAACAGCT CACCCTGAAC GGGATTTATA CACACATCAC TAAAAATTAT 
CCCTACTACA GGACTGCGGA CAAGGGCTGG CAGAATTCAA TTCGCCACAA TCTCTCTCTG 
AATCGTTATT TCATCAAAGT GCCGCGTTCC CAGGAAGAAC CAGGCAAAGG CTCGTTCTGG 
AGGATAGACC CAGCCTCTGA AAGCAAATTA ATAGAACAGG CTTTTAGGAA ACGACGGCCT 
AGGGGCGTGC CCTGCTTTAG AACCCCTCTG GGACCGCTCT CTTCTAGGAG TGCCCCAGCC 
TCTCCCAATC ACGCGGGAGT GCTGTCTGCT CACTCTAGTG GCGCCCAGAC CCCTGAGAGC 
CTGTCGAGGG AAGGTTCGCC GGCCCCCCTG GAGCCTGAGC CTGGCGCTGC ACAGCCCAAA 
CTCGCTGTCA TCCAGGAAGC CCGGTTTGCC CAGAGCGCCC CAGGGTCACC TCTGTCCAGT 
CAGCCAGTCT TAATCACCGT CCAGCGGCAG CTACCACAGG CCATCAAGCC TGTCACCTAC 
ACTGTGGCCA CCCCAGTGAC CACCTCGACC TCCCAGCCAC CCGTCGTGCA GACGGTTCAC 
GTCGTCCACC AGATCCCAGC GGTGTCGGTC ACCAGTGTGG CCGGACTGGC CCCAGCGAAC 
ACGTACACTG TCTCTGGACA AGCTGTGGTC ACCCCGGCAG CCGTGCTGGC CCCTCCTAAG 
GCAGAGGCCC AGGAGAATGG AGACCACAGG GAAGTCAAAG TGAAAGTAGA GCCTATTCCC 
GCCATTGGCC ACGCCACGCT CGGCACTGCC AGCCGGATCA TTCAGACGGC ACAGACCACC 
CCGGTCCAGA CGGTGACCAT AGTACAACAG GCACCTCTAG GTCAACACCA GCTACCAATA 
AAAACTGTAA CACAAAACGG CACTCACGTG GCATCAGTCC CCACTGCGGT CCACGGCCAG 
GTGAACAATG CCGCGGCGAG TCCTTTGCAC ATGTTGGCAA CACACGCATC CGCATCGGCC 
TCCCTGCCCA CAAAGCGCCA CAACGGTGAC CAGCCGGAGC AGCCGGAGCT GAAGCGGATC 
AAGACAGAAG ACGGCGAGGG CATCGTCATT GCCCTGAGCG TGGACACGCC ACCGGCAGCC 
GTAAGGGAAA AGGGTGTCCA GAACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

FOXK2, regulted by miR-1271-5p, promotes cell growth and indicates unfavorable prognosis in hepatocellular carcinoma.
The international journal of biochemistry & cell biology88155-161(2017 07)
Lin MF,Yang YF,Peng ZP,Zhang MF,Liang JY,Chen W,Liu XH,Zheng YL

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

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FOXK2 cDNA ORF clone, Homo sapiens(human)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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