BEX5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	BEX5
Entrez Gene ID	340542
Full Name	brain expressed X-linked 5
Synonyms	NGFRAP1L1
General protein information	Preferred Names brain expressed X-linked 5 Names protein BEX5 BEX family member 5 NGFRAP1-like 1 NGFRAP1-like protein 1 brain-expressed X-linked protein 5 nerve growth factor receptor-associated protein 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xq22.1
Disorder MIM:	300693

mRNA and Protein(s)

mRNA	Protein	Name
NM_001012978.3	NP_001012996.1	protein BEX5
NM_001159560.1	NP_001153032.1	protein BEX5
NM_001012978.2	NP_001012996.1	protein BEX5

Pathways from BioSystems

Homologies

Homo sapiens (human)	BEX5	NP_001012996.1
Bos taurus (cattle)	BEX5	NP_001069203.1
Canis lupus familiaris (dog)	BEX5	XP_005641645.1
Pan troglodytes (chimpanzee)	BEX5	XP_003317628.1

Gene Ontology
Bibliography

Related articles in PubMed

Adaptive evolution and frequent gene conversion in the brain expressed X-linked gene family in mammals.
Zhang L
Biochemical genetics46(5-6)293-311(2008 Jun)

Mammalian BEX, WEX and GASP genes: coding and non-coding chimaerism sustained by gene conversion events.
Winter EE, Ponting CP
BMC evolutionary biology554(2005 Oct)

Characterization of the Bex gene family in humans, mice, and rats.
Alvarez E, Zhou W, Witta SE, Freed CR
Gene357(1)18-28(2005 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following BEX5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BEX5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu13613	NM_001159560.1 Latest version!	Homo sapiens brain expressed X-linked 5 (BEX5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu13613	NM_001012978.3 Latest version!	Homo sapiens brain expressed X-linked 5 (BEX5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu13613	NM_001012978.2	Homo sapiens brain expressed X-linked 5 (BEX5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

BEX5 ( NM_001012978.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001012996.1 Homo sapiens brain expressed X-linked 5 (BEX5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu13613
Clone ID Related Accession (Same CDS sequence)	NM_001012978.3 , NM_001159560.1 , NM_001012978.2
Accession Version	NM_001012978.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 336bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-30
Organism	Homo sapiens(human)
Product	protein BEX5
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC106955.2 and AY833564.1. On Nov 22, 2018 this sequence version replaced NM_001012978.2. Transcript Variant: This variant (1) represents the shorter transcript. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: SRR5189652.182594.1, SRR5189652.45374.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000333643.4/ ENSP00000328030.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAAAATG TCCCCAAGGA AAACAAAGTT GTGGAGAAGG CCCCAGTGCA GAATGAAGCC 
CCCGCTTTAG GAGGTGGTGA ATACCAGGAG CCTGGAGGAA ATGTTAAAGG GGTTTGGGCT 
CCACCTGCCC CGGGTTTTGG AGAGGATGTG CCCAATAGGC TTGTCGATAA CATTGATATG 
ATAGATGGAG ATGGAGATGA TATGGAACGG TTCATGGAGG AGATGAGAGA GCTAAGGAGG 
AAAATTAGGG AACTTCAGTT GAGGTACAGT CTGCGCATTC TTATAGGGGA CCCTCCTCAC 
CATGATCATC ATGATGAGTT TTGCCTTATG CCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001012996.1
CDS	224..559
Translation	MENVPKENKVVEKAPVQNEAPALGGGEYQEPGGNVKGVWAPPAPGFGEDVPNRLVDNIDMIDGDGDDMERFMEEMRELRRKIRELQLRYSLRILIGDPPHHDHHDEFCLMP

Target ORF information:

RefSeq Version	NM_001012978.3
Organism	Homo sapiens(human)
Definition	Homo sapiens brain expressed X-linked 5 (BEX5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001012978.3

ORF Insert Sequence:

ATGGAAAATG TCCCCAAGGA AAACAAAGTT GTGGAGAAGG CCCCAGTGCA GAATGAAGCC 
CCCGCTTTAG GAGGTGGTGA ATACCAGGAG CCTGGAGGAA ATGTTAAAGG GGTTTGGGCT 
CCACCTGCCC CGGGTTTTGG AGAGGATGTG CCCAATAGGC TTGTCGATAA CATTGATATG 
ATAGATGGAG ATGGAGATGA TATGGAACGG TTCATGGAGG AGATGAGAGA GCTAAGGAGG 
AAAATTAGGG AACTTCAGTT GAGGTACAGT CTGCGCATTC TTATAGGGGA CCCTCCTCAC 
CATGATCATC ATGATGAGTT TTGCCTTATG CCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BEX5 ( NM_001159560.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001153032.1 Homo sapiens brain expressed X-linked 5 (BEX5), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu13613
Clone ID Related Accession (Same CDS sequence)	NM_001012978.3 , NM_001159560.1 , NM_001012978.2
Accession Version	NM_001159560.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 336bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-03
Organism	Homo sapiens(human)
Product	protein BEX5
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AI985090.1 and AY833564.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: SRR5189652.44311.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2145240 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAAAATG TCCCCAAGGA AAACAAAGTT GTGGAGAAGG CCCCAGTGCA GAATGAAGCC 
CCCGCTTTAG GAGGTGGTGA ATACCAGGAG CCTGGAGGAA ATGTTAAAGG GGTTTGGGCT 
CCACCTGCCC CGGGTTTTGG AGAGGATGTG CCCAATAGGC TTGTCGATAA CATTGATATG 
ATAGATGGAG ATGGAGATGA TATGGAACGG TTCATGGAGG AGATGAGAGA GCTAAGGAGG 
AAAATTAGGG AACTTCAGTT GAGGTACAGT CTGCGCATTC TTATAGGGGA CCCTCCTCAC 
CATGATCATC ATGATGAGTT TTGCCTTATG CCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001153032.1
CDS	303..638
Translation	MENVPKENKVVEKAPVQNEAPALGGGEYQEPGGNVKGVWAPPAPGFGEDVPNRLVDNIDMIDGDGDDMERFMEEMRELRRKIRELQLRYSLRILIGDPPHHDHHDEFCLMP

Target ORF information:

RefSeq Version	NM_001159560.1
Organism	Homo sapiens(human)
Definition	Homo sapiens brain expressed X-linked 5 (BEX5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001159560.1

ORF Insert Sequence:

ATGGAAAATG TCCCCAAGGA AAACAAAGTT GTGGAGAAGG CCCCAGTGCA GAATGAAGCC 
CCCGCTTTAG GAGGTGGTGA ATACCAGGAG CCTGGAGGAA ATGTTAAAGG GGTTTGGGCT 
CCACCTGCCC CGGGTTTTGG AGAGGATGTG CCCAATAGGC TTGTCGATAA CATTGATATG 
ATAGATGGAG ATGGAGATGA TATGGAACGG TTCATGGAGG AGATGAGAGA GCTAAGGAGG 
AAAATTAGGG AACTTCAGTT GAGGTACAGT CTGCGCATTC TTATAGGGGA CCCTCCTCAC 
CATGATCATC ATGATGAGTT TTGCCTTATG CCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BEX5 ( NM_001012978.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001012996.1 Homo sapiens brain expressed X-linked 5 (BEX5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu13613
Clone ID Related Accession (Same CDS sequence)	NM_001012978.3 , NM_001159560.1 , NM_001012978.2
Accession Version	NM_001012978.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 336bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	protein BEX5
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC106955.2 and AY833564.1. On Apr 29, 2009 this sequence version replaced NM_001012978.1. Transcript Variant: This variant (1) represents the shorter transcript. Both variants 1 and 2 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: AY833564.1, BC042818.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAAAATG TCCCCAAGGA AAACAAAGTT GTGGAGAAGG CCCCAGTGCA GAATGAAGCC 
CCCGCTTTAG GAGGTGGTGA ATACCAGGAG CCTGGAGGAA ATGTTAAAGG GGTTTGGGCT 
CCACCTGCCC CGGGTTTTGG AGAGGATGTG CCCAATAGGC TTGTCGATAA CATTGATATG 
ATAGATGGAG ATGGAGATGA TATGGAACGG TTCATGGAGG AGATGAGAGA GCTAAGGAGG 
AAAATTAGGG AACTTCAGTT GAGGTACAGT CTGCGCATTC TTATAGGGGA CCCTCCTCAC 
CATGATCATC ATGATGAGTT TTGCCTTATG CCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001012996.1
CDS	261..596
Translation	MENVPKENKVVEKAPVQNEAPALGGGEYQEPGGNVKGVWAPPAPGFGEDVPNRLVDNIDMIDGDGDDMERFMEEMRELRRKIRELQLRYSLRILIGDPPHHDHHDEFCLMP

Target ORF information:

RefSeq Version	NM_001012978.2
Organism	Homo sapiens(human)
Definition	Homo sapiens brain expressed X-linked 5 (BEX5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001012978.2

ORF Insert Sequence:

ATGGAAAATG TCCCCAAGGA AAACAAAGTT GTGGAGAAGG CCCCAGTGCA GAATGAAGCC 
CCCGCTTTAG GAGGTGGTGA ATACCAGGAG CCTGGAGGAA ATGTTAAAGG GGTTTGGGCT 
CCACCTGCCC CGGGTTTTGG AGAGGATGTG CCCAATAGGC TTGTCGATAA CATTGATATG 
ATAGATGGAG ATGGAGATGA TATGGAACGG TTCATGGAGG AGATGAGAGA GCTAAGGAGG 
AAAATTAGGG AACTTCAGTT GAGGTACAGT CTGCGCATTC TTATAGGGGA CCCTCCTCAC 
CATGATCATC ATGATGAGTT TTGCCTTATG CCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Adaptive evolution and frequent gene conversion in the brain expressed X-linked gene family in mammals.
Biochemical genetics46(5-6)293-311(2008 Jun)
Zhang L

Mammalian BEX, WEX and GASP genes: coding and non-coding chimaerism sustained by gene conversion events.
BMC evolutionary biology554(2005 Oct)
Winter EE,Ponting CP

Characterization of the Bex gene family in humans, mice, and rats.
Gene357(1)18-28(2005 Aug)
Alvarez E,Zhou W,Witta SE,Freed CR