| Gene Symbol | ICAM4 |
| Entrez Gene ID | 3386 |
| Full Name | intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) |
| Synonyms | CD242,LW |
| General protein information |
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| Gene Type | protein-coding |
| Organism | Homo sapiens(Human) |
| Genome | |
| Summary | This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]. |
| Disorder MIM: | |
| Disorder Html: | [Blood group, Landsteiner-Wiener], 111250 (3) |









































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