EHD2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	EHD2
Entrez Gene ID	30846
Full Name	EH domain containing 2
Synonyms	PAST2
General protein information	Preferred Names EH domain containing 2 Names EH domain-containing protein 2 PAST homolog 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.33
Summary	This gene encodes a member of the EH domain-containing protein family. These proteins are characterized by a C-terminal EF-hand domain, a nucleotide-binding consensus site at the N terminus and a bipartite nuclear localization signal. The encoded protein interacts with the actin cytoskeleton through an N-terminal domain and also binds to an EH domain-binding protein through the C-terminal EH domain. This interaction appears to connect clathrin-dependent endocytosis to actin, suggesting that this gene product participates in the endocytic pathway. [provided by RefSeq, Jul 2008].
Disorder MIM:	605890

mRNA and Protein(s)

mRNA	Protein	Name
NM_014601.3	NP_055416.2	EH domain-containing protein 2
NM_014601.4	NP_055416.2	EH domain-containing protein 2

Pathways from BioSystems

Homologies

Bos taurus (cattle)	EHD2	NP_001039896.1
Danio rerio (zebrafish)	ehd2	NP_956357.1
	LOC717477	XP_002801362.1
Canis lupus familiaris (dog)	EHD2	XP_541532.2
Mus musculus (house mouse)	Ehd2	NP_694708.2
Xenopus tropicalis (tropical clawed frog)	ehd2	NP_001025664.1
Homo sapiens (human)	EHD2	NP_055416.2
Pan troglodytes (chimpanzee)	EHD2	NP_001233562.1
Rattus norvegicus (Norway rat)	Ehd2	NP_001020068.1

Gene Ontology
Bibliography

Related articles in PubMed

Prognostic implication of histological features associated with EHD2 expression in papillary thyroid carcinoma.
Kim Y, Kim MH, Jeon S, Kim J, Kim C, Bae JS, Jung CK
PloS one12(3)e0174737(2017)

Decreased Expression of EHD2 Promotes Tumor Metastasis and Indicates Poor Prognosis in Hepatocellular Carcinoma.
Liu J, Ni W, Qu L, Cui X, Lin Z, Liu Q, Zhou H, Ni R
Digestive diseases and sciences61(9)2554-67(2016 09)

Role of the EHD2 unstructured loop in dimerization, protein binding and subcellular localization.
Bahl K, Naslavsky N, Caplan S
PloS one10(4)e0123710(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Our prognostic model is useful for predicting persistent/recurrent disease after surgery of Papillary thyroid carcinoma (PTC). EHD2 mRNA expression could be a novel prognostic marker for PTC patients.
Title: Prognostic implication of histological features associated with EHD2 expression in papillary thyroid carcinoma.

EHD2 expression, along with the epithelial marker E-cadherin, was markedly reduced in tumor tissues than in adjacent noncancerous tissues. Molecular data indicated that EHD2 inhibited migration and invasion of hepatocellular carcinoma probably by interacting with E-cadherin.
Title: Decreased Expression of EHD2 Promotes Tumor Metastasis and Indicates Poor Prognosis in Hepatocellular Carcinoma.

Downregulation of EHD2 was associated with migration and invasion by abrogating the expression of Rac1 in breast cancer patients.
Title: Role of EHD2 in migration and invasion of human breast cancer cells.

EHD2 can inhibit the metastasis of human breast cancer by regulating the epithelial-to-mesenchymal transition markers E-cadherin and N-cadherin.
Title: Decreased expression and prognostic role of EHD2 in human breast carcinoma: correlation with E-cadherin.

Data suggest that the EH-domain containing 2 protein (EHD2) NPF phenylalanine residue is crucial for EHD2 localization to the plasma membrane, whereas the proline residue is essential for EHD2 dimerization and binding.
Title: Role of the EHD2 unstructured loop in dimerization, protein binding and subcellular localization.

The following EHD2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EHD2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu31430	NM_014601.4 Latest version!	Homo sapiens EH domain containing 2 (EHD2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
View Old Accession Versions >>
OHu31430	NM_014601.3	Homo sapiens EH domain containing 2 (EHD2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

EHD2 ( NM_014601.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_055416.2 Homo sapiens EH domain containing 2 (EHD2), mRNA.

Price & Availability↑

CloneID	OHu31430
Clone ID Related Accession (Same CDS sequence)	NM_014601.3 , NM_014601.4
Accession Version	NM_014601.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1632bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	EH domain-containing protein 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA094880.1, AK315548.1, DB260808.1, BC014445.1 and BG677716.1. On Apr 8, 2008 this sequence version replaced NM_014601.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC014445.1, SRR1660809.52005.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTCAGCT GGCTGAAGCG GGGCGGGGCA CGGGGCCAGC AGCCCGAGGC CATCCGCACG 
GTGACCTCGG CCCTCAAGGA GCTGTACCGC ACGAAGCTGC TGCCGCTGGA GGAGCACTAC 
CGCTTTGGGG CCTTCCACTC GCCGGCCCTG GAGGACGCAG ACTTCGACGG CAAGCCCATG 
GTGCTGGTGG CCGGCCAGTA CAGCACGGGC AAGACCAGCT TCATCCAGTA CCTGCTGGAG 
CAGGAGGTGC CCGGCTCCCG CGTGGGGCCT GAGCCCACCA CCGACTGCTT TGTGGCCGTC 
ATGCACGGGG ACACTGAGGG CACCGTGCCC GGCAACGCCC TCGTCGTGGA CCCGGACAAG 
CCCTTCCGCA AACTCAACCC TTTCGGAAAC ACCTTCCTCA ACAGGTTCAT GTGTGCCCAG 
CTCCCTAATC AGGTCCTGGA GAGCATCAGC ATCATCGACA CCCCGGGTAT CCTGTCGGGT 
GCCAAGCAGA GAGTGAGCCG CGGCTACGAC TTCCCGGCCG TGCTGCGCTG GTTCGCGGAG 
CGCGTGGACC TCATCATCCT GCTCTTTGAT GCGCACAAGC TGGAGATCTC GGACGAGTTC 
TCAGAGGCCA TCGGCGCGTT GCGGGGCCAT GAGGACAAGA TCCGCGTGGT GCTCAACAAG 
GCCGACATGG TGGAGACGCA GCAGCTGATG CGCGTCTACG GCGCGCTCAT GTGGGCGCTG 
GGCAAGGTGG TGGGCACGCC CGAGGTGCTG CGCGTCTACA TCGGCTCCTT CTGGTCCCAG 
CCCCTCCTCG TGCCCGACAA CCGGCGCCTC TTCGAGCTGG AGGAGCAGGA CCTCTTCCGC 
GACATCCAGG GCCTGCCCCG GCACGCAGCC TTGCGCAAGC TCAACGACCT GGTGAAGAGG 
GCCCGGCTGG TGCGAGTTCA CGCTTACATC ATCAGCTACC TGAAGAAGGA GATGCCCTCT 
GTGTTTGGGA AGGAGAACAA GAAGAAGCAG CTGATCCTCA AACTGCCCGT CATCTTTGCG 
AAGATTCAGC TGGAACATCA CATCTCCCCT GGGGACTTTC CTGATTGCCA GAAAATGCAG 
GAGCTGCTGA TGGCGCACGA CTTCACCAAG TTTCACTCGC TGAAGCCGAA GCTGCTAGAG 
GCACTGGACG AGATGCTGAC GCACGACATC GCCAAGCTCA TGCCCCTGCT GCGGCAGGAG 
GAGCTGGAGA GCACCGAGGT GGGCGTGCAG GGGGGCGCTT TTGAGGGCAC CCACATGGGC 
CCGTTTGTGG AGCGGGGACC TGACGAGGCC ATGGAGGACG GCGAGGAGGG CTCGGACGAC 
GAGGCCGAGT GGGTGGTGAC CAAGGACAAG TCCAAATACG ACGAGATCTT CTACAACCTG 
GCGCCTGCCG ACGGCAAGCT GAGCGGCTCC AAGGCCAAGA CCTGGATGGT GGGGACCAAG 
CTCCCCAACT CAGTGCTGGG GCGCATCTGG AAGCTCAGCG ATGTGGACCG CGACGGCATG 
CTGGATGATG AGGAGTTCGC GCTGGCCAGC CACCTCATCG AGGCCAAGCT GGAAGGCCAC 
GGGCTGCCCG CCAACCTGCC CCGTCGCCTG GTGCCACCCT CCAAGCGACG CCACAAGGGC 
TCCGCCGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055416.2
CDS	251..1882
Translation	MFSWLKRGGARGQQPEAIRTVTSALKELYRTKLLPLEEHYRFGAFHSPALEDADFDGKPMVLVAGQYSTGKTSFIQYLLEQEVPGSRVGPEPTTDCFVAVMHGDTEGTVPGNALVVDPDKPFRKLNPFGNTFLNRFMCAQLPNQVLESISIIDTPGILSGAKQRVSRGYDFPAVLRWFAERVDLIILLFDAHKLEISDEFSEAIGALRGHEDKIRVVLNKADMVETQQLMRVYGALMWALGKVVGTPEVLRVYIGSFWSQPLLVPDNRRLFELEEQDLFRDIQGLPRHAALRKLNDLVKRARLVRVHAYIISYLKKEMPSVFGKENKKKQLILKLPVIFAKIQLEHHISPGDFPDCQKMQELLMAHDFTKFHSLKPKLLEALDEMLTHDIAKLMPLLRQEELESTEVGVQGGAFEGTHMGPFVERGPDEAMEDGEEGSDDEAEWVVTKDKSKYDEIFYNLAPADGKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDGMLDDEEFALASHLIEAKLEGHGLPANLPRRLVPPSKRRHKGSAE

Target ORF information:

RefSeq Version	NM_014601.3
Organism	Homo sapiens(human)
Definition	Homo sapiens EH domain containing 2 (EHD2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014601.3

ORF Insert Sequence:

ATGTTCAGCT GGCTGAAGCG GGGCGGGGCA CGGGGCCAGC AGCCCGAGGC CATCCGCACG 
GTGACCTCGG CCCTCAAGGA GCTGTACCGC ACGAAGCTGC TGCCGCTGGA GGAGCACTAC 
CGCTTTGGGG CCTTCCACTC GCCGGCCCTG GAGGACGCAG ACTTCGACGG CAAGCCCATG 
GTGCTGGTGG CCGGCCAGTA CAGCACGGGC AAGACCAGCT TCATCCAGTA CCTGCTGGAG 
CAGGAGGTGC CCGGCTCCCG CGTGGGGCCT GAGCCCACCA CCGACTGCTT TGTGGCCGTC 
ATGCACGGGG ACACTGAGGG CACCGTGCCC GGCAACGCCC TCGTCGTGGA CCCGGACAAG 
CCCTTCCGCA AACTCAACCC TTTCGGAAAC ACCTTCCTCA ACAGGTTCAT GTGTGCCCAG 
CTCCCTAATC AGGTCCTGGA GAGCATCAGC ATCATCGACA CCCCGGGTAT CCTGTCGGGT 
GCCAAGCAGA GAGTGAGCCG CGGCTACGAC TTCCCGGCCG TGCTGCGCTG GTTCGCGGAG 
CGCGTGGACC TCATCATCCT GCTCTTTGAT GCGCACAAGC TGGAGATCTC GGACGAGTTC 
TCAGAGGCCA TCGGCGCGTT GCGGGGCCAT GAGGACAAGA TCCGCGTGGT GCTCAACAAG 
GCCGACATGG TGGAGACGCA GCAGCTGATG CGCGTCTACG GCGCGCTCAT GTGGGCGCTG 
GGCAAGGTGG TGGGCACGCC CGAGGTGCTG CGCGTCTACA TCGGCTCCTT CTGGTCCCAG 
CCCCTCCTCG TGCCCGACAA CCGGCGCCTC TTCGAGCTGG AGGAGCAGGA CCTCTTCCGC 
GACATCCAGG GCCTGCCCCG GCACGCAGCC TTGCGCAAGC TCAACGACCT GGTGAAGAGG 
GCCCGGCTGG TGCGAGTTCA CGCTTACATC ATCAGCTACC TGAAGAAGGA GATGCCCTCT 
GTGTTTGGGA AGGAGAACAA GAAGAAGCAG CTGATCCTCA AACTGCCCGT CATCTTTGCG 
AAGATTCAGC TGGAACATCA CATCTCCCCT GGGGACTTTC CTGATTGCCA GAAAATGCAG 
GAGCTGCTGA TGGCGCACGA CTTCACCAAG TTTCACTCGC TGAAGCCGAA GCTGCTAGAG 
GCACTGGACG AGATGCTGAC GCACGACATC GCCAAGCTCA TGCCCCTGCT GCGGCAGGAG 
GAGCTGGAGA GCACCGAGGT GGGCGTGCAG GGGGGCGCTT TTGAGGGCAC CCACATGGGC 
CCGTTTGTGG AGCGGGGACC TGACGAGGCC ATGGAGGACG GCGAGGAGGG CTCGGACGAC 
GAGGCCGAGT GGGTGGTGAC CAAGGACAAG TCCAAATACG ACGAGATCTT CTACAACCTG 
GCGCCTGCCG ACGGCAAGCT GAGCGGCTCC AAGGCCAAGA CCTGGATGGT GGGGACCAAG 
CTCCCCAACT CAGTGCTGGG GCGCATCTGG AAGCTCAGCG ATGTGGACCG CGACGGCATG 
CTGGATGATG AGGAGTTCGC GCTGGCCAGC CACCTCATCG AGGCCAAGCT GGAAGGCCAC 
GGGCTGCCCG CCAACCTGCC CCGTCGCCTG GTGCCACCCT CCAAGCGACG CCACAAGGGC 
TCCGCCGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EHD2 ( NM_014601.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_055416.2 Homo sapiens EH domain containing 2 (EHD2), mRNA.

Price & Availability↑

CloneID	OHu31430
Clone ID Related Accession (Same CDS sequence)	NM_014601.3 , NM_014601.4
Accession Version	NM_014601.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1632bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-16
Organism	Homo sapiens(human)
Product	EH domain-containing protein 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK315548.1, DB260808.1, BC014445.1 and BG677716.1. On Nov 23, 2018 this sequence version replaced NM_014601.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC014445.1, SRR1660809.52005.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000263277.8/ ENSP00000263277.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTTCAGCT GGCTGAAGCG GGGCGGGGCA CGGGGCCAGC AGCCCGAGGC CATCCGCACG 
GTGACCTCGG CCCTCAAGGA GCTGTACCGC ACGAAGCTGC TGCCGCTGGA GGAGCACTAC 
CGCTTTGGGG CCTTCCACTC GCCGGCCCTG GAGGACGCAG ACTTCGACGG CAAGCCCATG 
GTGCTGGTGG CCGGCCAGTA CAGCACGGGC AAGACCAGCT TCATCCAGTA CCTGCTGGAG 
CAGGAGGTGC CCGGCTCCCG CGTGGGGCCT GAGCCCACCA CCGACTGCTT TGTGGCCGTC 
ATGCACGGGG ACACTGAGGG CACCGTGCCC GGCAACGCCC TCGTCGTGGA CCCGGACAAG 
CCCTTCCGCA AACTCAACCC TTTCGGAAAC ACCTTCCTCA ACAGGTTCAT GTGTGCCCAG 
CTCCCTAATC AGGTCCTGGA GAGCATCAGC ATCATCGACA CCCCGGGTAT CCTGTCGGGT 
GCCAAGCAGA GAGTGAGCCG CGGCTACGAC TTCCCGGCCG TGCTGCGCTG GTTCGCGGAG 
CGCGTGGACC TCATCATCCT GCTCTTTGAT GCGCACAAGC TGGAGATCTC GGACGAGTTC 
TCAGAGGCCA TCGGCGCGTT GCGGGGCCAT GAGGACAAGA TCCGCGTGGT GCTCAACAAG 
GCCGACATGG TGGAGACGCA GCAGCTGATG CGCGTCTACG GCGCGCTCAT GTGGGCGCTG 
GGCAAGGTGG TGGGCACGCC CGAGGTGCTG CGCGTCTACA TCGGCTCCTT CTGGTCCCAG 
CCCCTCCTCG TGCCCGACAA CCGGCGCCTC TTCGAGCTGG AGGAGCAGGA CCTCTTCCGC 
GACATCCAGG GCCTGCCCCG GCACGCAGCC TTGCGCAAGC TCAACGACCT GGTGAAGAGG 
GCCCGGCTGG TGCGAGTTCA CGCTTACATC ATCAGCTACC TGAAGAAGGA GATGCCCTCT 
GTGTTTGGGA AGGAGAACAA GAAGAAGCAG CTGATCCTCA AACTGCCCGT CATCTTTGCG 
AAGATTCAGC TGGAACATCA CATCTCCCCT GGGGACTTTC CTGATTGCCA GAAAATGCAG 
GAGCTGCTGA TGGCGCACGA CTTCACCAAG TTTCACTCGC TGAAGCCGAA GCTGCTAGAG 
GCACTGGACG AGATGCTGAC GCACGACATC GCCAAGCTCA TGCCCCTGCT GCGGCAGGAG 
GAGCTGGAGA GCACCGAGGT GGGCGTGCAG GGGGGCGCTT TTGAGGGCAC CCACATGGGC 
CCGTTTGTGG AGCGGGGACC TGACGAGGCC ATGGAGGACG GCGAGGAGGG CTCGGACGAC 
GAGGCCGAGT GGGTGGTGAC CAAGGACAAG TCCAAATACG ACGAGATCTT CTACAACCTG 
GCGCCTGCCG ACGGCAAGCT GAGCGGCTCC AAGGCCAAGA CCTGGATGGT GGGGACCAAG 
CTCCCCAACT CAGTGCTGGG GCGCATCTGG AAGCTCAGCG ATGTGGACCG CGACGGCATG 
CTGGATGATG AGGAGTTCGC GCTGGCCAGC CACCTCATCG AGGCCAAGCT GGAAGGCCAC 
GGGCTGCCCG CCAACCTGCC CCGTCGCCTG GTGCCACCCT CCAAGCGACG CCACAAGGGC 
TCCGCCGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055416.2
CDS	173..1804
Translation	MFSWLKRGGARGQQPEAIRTVTSALKELYRTKLLPLEEHYRFGAFHSPALEDADFDGKPMVLVAGQYSTGKTSFIQYLLEQEVPGSRVGPEPTTDCFVAVMHGDTEGTVPGNALVVDPDKPFRKLNPFGNTFLNRFMCAQLPNQVLESISIIDTPGILSGAKQRVSRGYDFPAVLRWFAERVDLIILLFDAHKLEISDEFSEAIGALRGHEDKIRVVLNKADMVETQQLMRVYGALMWALGKVVGTPEVLRVYIGSFWSQPLLVPDNRRLFELEEQDLFRDIQGLPRHAALRKLNDLVKRARLVRVHAYIISYLKKEMPSVFGKENKKKQLILKLPVIFAKIQLEHHISPGDFPDCQKMQELLMAHDFTKFHSLKPKLLEALDEMLTHDIAKLMPLLRQEELESTEVGVQGGAFEGTHMGPFVERGPDEAMEDGEEGSDDEAEWVVTKDKSKYDEIFYNLAPADGKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDGMLDDEEFALASHLIEAKLEGHGLPANLPRRLVPPSKRRHKGSAE

Target ORF information:

RefSeq Version	NM_014601.4
Organism	Homo sapiens(human)
Definition	Homo sapiens EH domain containing 2 (EHD2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014601.4

ORF Insert Sequence:

ATGTTCAGCT GGCTGAAGCG GGGCGGGGCA CGGGGCCAGC AGCCCGAGGC CATCCGCACG 
GTGACCTCGG CCCTCAAGGA GCTGTACCGC ACGAAGCTGC TGCCGCTGGA GGAGCACTAC 
CGCTTTGGGG CCTTCCACTC GCCGGCCCTG GAGGACGCAG ACTTCGACGG CAAGCCCATG 
GTGCTGGTGG CCGGCCAGTA CAGCACGGGC AAGACCAGCT TCATCCAGTA CCTGCTGGAG 
CAGGAGGTGC CCGGCTCCCG CGTGGGGCCT GAGCCCACCA CCGACTGCTT TGTGGCCGTC 
ATGCACGGGG ACACTGAGGG CACCGTGCCC GGCAACGCCC TCGTCGTGGA CCCGGACAAG 
CCCTTCCGCA AACTCAACCC TTTCGGAAAC ACCTTCCTCA ACAGGTTCAT GTGTGCCCAG 
CTCCCTAATC AGGTCCTGGA GAGCATCAGC ATCATCGACA CCCCGGGTAT CCTGTCGGGT 
GCCAAGCAGA GAGTGAGCCG CGGCTACGAC TTCCCGGCCG TGCTGCGCTG GTTCGCGGAG 
CGCGTGGACC TCATCATCCT GCTCTTTGAT GCGCACAAGC TGGAGATCTC GGACGAGTTC 
TCAGAGGCCA TCGGCGCGTT GCGGGGCCAT GAGGACAAGA TCCGCGTGGT GCTCAACAAG 
GCCGACATGG TGGAGACGCA GCAGCTGATG CGCGTCTACG GCGCGCTCAT GTGGGCGCTG 
GGCAAGGTGG TGGGCACGCC CGAGGTGCTG CGCGTCTACA TCGGCTCCTT CTGGTCCCAG 
CCCCTCCTCG TGCCCGACAA CCGGCGCCTC TTCGAGCTGG AGGAGCAGGA CCTCTTCCGC 
GACATCCAGG GCCTGCCCCG GCACGCAGCC TTGCGCAAGC TCAACGACCT GGTGAAGAGG 
GCCCGGCTGG TGCGAGTTCA CGCTTACATC ATCAGCTACC TGAAGAAGGA GATGCCCTCT 
GTGTTTGGGA AGGAGAACAA GAAGAAGCAG CTGATCCTCA AACTGCCCGT CATCTTTGCG 
AAGATTCAGC TGGAACATCA CATCTCCCCT GGGGACTTTC CTGATTGCCA GAAAATGCAG 
GAGCTGCTGA TGGCGCACGA CTTCACCAAG TTTCACTCGC TGAAGCCGAA GCTGCTAGAG 
GCACTGGACG AGATGCTGAC GCACGACATC GCCAAGCTCA TGCCCCTGCT GCGGCAGGAG 
GAGCTGGAGA GCACCGAGGT GGGCGTGCAG GGGGGCGCTT TTGAGGGCAC CCACATGGGC 
CCGTTTGTGG AGCGGGGACC TGACGAGGCC ATGGAGGACG GCGAGGAGGG CTCGGACGAC 
GAGGCCGAGT GGGTGGTGAC CAAGGACAAG TCCAAATACG ACGAGATCTT CTACAACCTG 
GCGCCTGCCG ACGGCAAGCT GAGCGGCTCC AAGGCCAAGA CCTGGATGGT GGGGACCAAG 
CTCCCCAACT CAGTGCTGGG GCGCATCTGG AAGCTCAGCG ATGTGGACCG CGACGGCATG 
CTGGATGATG AGGAGTTCGC GCTGGCCAGC CACCTCATCG AGGCCAAGCT GGAAGGCCAC 
GGGCTGCCCG CCAACCTGCC CCGTCGCCTG GTGCCACCCT CCAAGCGACG CCACAAGGGC 
TCCGCCGAGT GA