CFHR2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CFHR2
Entrez Gene ID	3080
Full Name	complement factor H related 2
Synonyms	CFHL2,FHR2,HFL3
General protein information	Preferred Names complement factor H related 2 Names complement factor H-related protein 2 DDESK59 FHR-2 H factor (complement)-like 3 factor H-related gene 2 h factor-like 3 h factor-like protein 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q31.3
Summary	This gene belongs to a family of complement factor H-related genes (CFHR), which are clustered together with complement factor H gene on chromosome 1, and are involved in regulation of complement. Mutations in CFHR genes have been associated with dense deposit disease and atypical haemolytic-uraemic syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2015].
Disorder MIM:	600889

mRNA and Protein(s)

mRNA	Protein	Name
XM_017001109.1	XP_016856598.1	complement factor H-related protein 2 isoform X3
XM_005245113.3	XP_005245170.1	complement factor H-related protein 2 isoform X4
XM_011509460.2	XP_011507762.1	complement factor H-related protein 2 isoform X5
NM_005666.3	NP_005657.1	complement factor H-related protein 2 isoform 1 precursor
NM_001312672.1	NP_001299601.1	complement factor H-related protein 2 isoform 2 precursor
XM_011509459.2	XP_011507761.1	complement factor H-related protein 2 isoform X2
NM_005666.4	NP_005657.1	complement factor H-related protein 2 isoform 1 precursor
XM_011509458.2	XP_011507760.1	complement factor H-related protein 2 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	CFHR2	NP_005657.1
Bos taurus (cattle)	CFHR2	XP_002694314.1

Gene Ontology
Bibliography

Related articles in PubMed

CFHR2-rs2986127 as a genetic protective marker for acute anterior uveitis in Chinese patients.
Huang XF, Wang Y, Li FF, Lin D, Dai ML, Wang QF, Jin ZB
The journal of gene medicine18(8)193-8(2016 Aug)

Sequence and Expression of Complement Factor H Gene Cluster Variants and Their Roles in Age-Related Macular Degeneration Risk.
Hughes AE, Bridgett S, Meng W, Li M, Curcio CA, Stambolian D, Bradley DT
Investigative ophthalmology & visual science57(6)2763-9(2016 05)

Factor H-related proteins determine complement-activating surfaces.
J?zsi M, Tortajada A, Uzonyi B, Goicoechea de Jorge E, Rodr?guez de C?rdoba S
Trends in immunology36(6)374-84(2015 Jun)

Atypical haemolytic-uraemic syndrome due to heterozygous mutations of CFH/CFHR1-3 and complement factor H 479.
Chaudhary P, Hepgur M, Sarkissian S, Smith RJ, Weitz IC
Blood transfusion = Trasfusione del sangue12(1)111-3(2014 Jan)

Complement factor H-related hybrid protein deregulates complement in dense deposit disease.
Chen Q, Wiesener M, Eberhardt HU, Hartmann A, Uzonyi B, Kirschfink M, Amann K, Buettner M, Goodship T, Hugo C, Skerka C, Zipfel PF
The Journal of clinical investigation124(1)145-55(2014 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Next-generation sequencing of the CFH region identified putatively functional variants (missense, splice site and indel) on the four common haplotypes. We found no expression of any of the five CFH-related genes in the retina or RPE/Choroid/Sclera, in contrast to the liver, which is the main source of the circulating proteins. [CFHR2]
Title: Sequence and Expression of Complement Factor H Gene Cluster Variants and Their Roles in Age-Related Macular Degeneration Risk.

Studies indicate that complement factor H-related proteins (FHR1-5) may enhance complement activation, with important implications for the role of these proteins in disease.
Title: Factor H-related proteins determine complement-activating surfaces.

Atypical haemolytic-uraemic syndrome due to heterozygous mutations of CFH/CFHR1-3 and complement factor H 479.
Title: Atypical haemolytic-uraemic syndrome due to heterozygous mutations of CFH/CFHR1-3 and complement factor H 479.

A hybrid CFHR2-CFHR5 plasma protein, arising from a chromosomal deletion mutation stabilizes the C3 convertase and reduces factor H-mediated convertase decay.
Title: Complement factor H-related hybrid protein deregulates complement in dense deposit disease.

Thus CFHR2 likely acts in concert with factor H, as CFHR2 inhibits convertases while simultaneously allowing factor H assisted degradation by factor I.
Title: Human factor H-related protein 2 (CFHR2) regulates complement activation.

The following CFHR2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CFHR2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu09645	NM_005666.4 Latest version!	Homo sapiens complement factor H related 2 (CFHR2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu58203	XM_011509459.2 Latest version!	Homo sapiens complement factor H related 2 (CFHR2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OHu58201	NM_001312672.1 Latest version!	Homo sapiens complement factor H related 2 (CFHR2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu34329	XM_005245113.3 Latest version!	Homo sapiens complement factor H related 2 (CFHR2), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu58202	XM_011509458.2 Latest version!	Homo sapiens complement factor H related 2 (CFHR2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu58204	XM_011509460.2 Latest version!	Homo sapiens complement factor H related 2 (CFHR2), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu87294	XM_017001109.1 Latest version!	Homo sapiens complement factor H related 2 (CFHR2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OHu09645	NM_005666.3	Homo sapiens complement factor H related 2 (CFHR2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CFHR2 ( NM_005666.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_005657.1 Homo sapiens complement factor H related 2 (CFHR2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu09645
Clone ID Related Accession (Same CDS sequence)	NM_005666.3 , NM_005666.4
Accession Version	NM_005666.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 813bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	complement factor H-related protein 2 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG563114.1, BC022283.1 and X64877.1. This sequence is a reference standard in the RefSeqGene project. On Aug 14, 2015 this sequence version replaced NM_005666.2. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X64877.1, BC022283.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145122, SAMEA2155590 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTGGCTCC TGGTCAGTGT AATTCTAATC TCACGGATAT CCTCTGTTGG GGGAGAAGCA 
ATGTTCTGTG ATTTTCCAAA AATAAACCAT GGAATTCTAT ATGATGAAGA AAAATATAAG 
CCATTTTCCC AAGTTCCTAC AGGGGAAGTT TTCTATTACT CCTGTGAATA TAATTTTGTG 
TCTCCTTCAA AATCCTTTTG GACTCGCATA ACGTGCGCAG AAGAAGGATG GTCACCAACA 
CCAAAGTGTC TCAGACTGTG TTTCTTTCCT TTTGTGGAAA ATGGTCATTC TGAATCTTCA 
GGACAAACAC ATCTGGAAGG TGATACTGTA CAAATTATTT GCAACACAGG ATACAGACTT 
CAAAACAATG AGAACAACAT TTCATGTGTA GAACGGGGCT GGTCCACTCC TCCCAAATGC 
AGGTCCACTA TTTCTGCAGA AAAATGTGGG CCCCCTCCAC CTATTGACAA TGGAGACATT 
ACTTCATTCC TGTTGTCAGT ATATGCTCCA GGTTCATCAG TTGAGTACCA GTGCCAGAAC 
TTGTATCAAC TTGAGGGTAA CAATCAAATA ACATGTAGAA ACGGACAATG GTCAGAACCA 
CCAAAATGCT TAGATCCATG TGTAATATCA CAAGAAATTA TGGAAAAATA TAACATAAAA 
TTAAAGTGGA CAAACCAACA AAAGCTTTAT TCAAGAACAG GTGACATAGT TGAATTTGTT 
TGTAAATCTG GATATCATCC AACAAAATCT CATTCATTTC GAGCAATGTG TCAGAATGGG 
AAACTGGTAT ATCCCAGTTG TGAAGAAAAA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005657.1
CDS	114..926
Translation	MWLLVSVILISRISSVGGEAMFCDFPKINHGILYDEEKYKPFSQVPTGEVFYYSCEYNFVSPSKSFWTRITCAEEGWSPTPKCLRLCFFPFVENGHSESSGQTHLEGDTVQIICNTGYRLQNNENNISCVERGWSTPPKCRSTISAEKCGPPPPIDNGDITSFLLSVYAPGSSVEYQCQNLYQLEGNNQITCRNGQWSEPPKCLDPCVISQEIMEKYNIKLKWTNQQKLYSRTGDIVEFVCKSGYHPTKSHSFRAMCQNGKLVYPSCEEK

Target ORF information:

RefSeq Version	NM_005666.3
Organism	Homo sapiens(human)
Definition	Homo sapiens complement factor H related 2 (CFHR2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005666.3

ORF Insert Sequence:

ATGTGGCTCC TGGTCAGTGT AATTCTAATC TCACGGATAT CCTCTGTTGG GGGAGAAGCA 
ATGTTCTGTG ATTTTCCAAA AATAAACCAT GGAATTCTAT ATGATGAAGA AAAATATAAG 
CCATTTTCCC AAGTTCCTAC AGGGGAAGTT TTCTATTACT CCTGTGAATA TAATTTTGTG 
TCTCCTTCAA AATCCTTTTG GACTCGCATA ACGTGCGCAG AAGAAGGATG GTCACCAACA 
CCAAAGTGTC TCAGACTGTG TTTCTTTCCT TTTGTGGAAA ATGGTCATTC TGAATCTTCA 
GGACAAACAC ATCTGGAAGG TGATACTGTA CAAATTATTT GCAACACAGG ATACAGACTT 
CAAAACAATG AGAACAACAT TTCATGTGTA GAACGGGGCT GGTCCACTCC TCCCAAATGC 
AGGTCCACTA TTTCTGCAGA AAAATGTGGG CCCCCTCCAC CTATTGACAA TGGAGACATT 
ACTTCATTCC TGTTGTCAGT ATATGCTCCA GGTTCATCAG TTGAGTACCA GTGCCAGAAC 
TTGTATCAAC TTGAGGGTAA CAATCAAATA ACATGTAGAA ACGGACAATG GTCAGAACCA 
CCAAAATGCT TAGATCCATG TGTAATATCA CAAGAAATTA TGGAAAAATA TAACATAAAA 
TTAAAGTGGA CAAACCAACA AAAGCTTTAT TCAAGAACAG GTGACATAGT TGAATTTGTT 
TGTAAATCTG GATATCATCC AACAAAATCT CATTCATTTC GAGCAATGTG TCAGAATGGG 
AAACTGGTAT ATCCCAGTTG TGAAGAAAAA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CFHR2 ( NM_005666.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005657.1 Homo sapiens complement factor H related 2 (CFHR2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu09645
Clone ID Related Accession (Same CDS sequence)	NM_005666.3 , NM_005666.4
Accession Version	NM_005666.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 813bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Homo sapiens(human)
Product	complement factor H-related protein 2 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL139418.9 and BC022283.1. This sequence is a reference standard in the RefSeqGene project. On May 16, 2018 this sequence version replaced NM_005666.3. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189664.62373.1, SRR5189652.151374.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145122, SAMEA2155590 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000367415.8/ ENSP00000356385.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTGGCTCC TGGTCAGTGT AATTCTAATC TCACGGATAT CCTCTGTTGG GGGAGAAGCA 
ATGTTCTGTG ATTTTCCAAA AATAAACCAT GGAATTCTAT ATGATGAAGA AAAATATAAG 
CCATTTTCCC AAGTTCCTAC AGGGGAAGTT TTCTATTACT CCTGTGAATA TAATTTTGTG 
TCTCCTTCAA AATCCTTTTG GACTCGCATA ACGTGCGCAG AAGAAGGATG GTCACCAACA 
CCAAAGTGTC TCAGACTGTG TTTCTTTCCT TTTGTGGAAA ATGGTCATTC TGAATCTTCA 
GGACAAACAC ATCTGGAAGG TGATACTGTA CAAATTATTT GCAACACAGG ATACAGACTT 
CAAAACAATG AGAACAACAT TTCATGTGTA GAACGGGGCT GGTCCACTCC TCCCAAATGC 
AGGTCCACTA TTTCTGCAGA AAAATGTGGG CCCCCTCCAC CTATTGACAA TGGAGACATT 
ACTTCATTCC TGTTGTCAGT ATATGCTCCA GGTTCATCAG TTGAGTACCA GTGCCAGAAC 
TTGTATCAAC TTGAGGGTAA CAATCAAATA ACATGTAGAA ACGGACAATG GTCAGAACCA 
CCAAAATGCT TAGATCCATG TGTAATATCA CAAGAAATTA TGGAAAAATA TAACATAAAA 
TTAAAGTGGA CAAACCAACA AAAGCTTTAT TCAAGAACAG GTGACATAGT TGAATTTGTT 
TGTAAATCTG GATATCATCC AACAAAATCT CATTCATTTC GAGCAATGTG TCAGAATGGG 
AAACTGGTAT ATCCCAGTTG TGAAGAAAAA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005657.1
CDS	144..956
Translation	MWLLVSVILISRISSVGGEAMFCDFPKINHGILYDEEKYKPFSQVPTGEVFYYSCEYNFVSPSKSFWTRITCAEEGWSPTPKCLRLCFFPFVENGHSESSGQTHLEGDTVQIICNTGYRLQNNENNISCVERGWSTPPKCRSTISAEKCGPPPPIDNGDITSFLLSVYAPGSSVEYQCQNLYQLEGNNQITCRNGQWSEPPKCLDPCVISQEIMEKYNIKLKWTNQQKLYSRTGDIVEFVCKSGYHPTKSHSFRAMCQNGKLVYPSCEEK

Target ORF information:

RefSeq Version	NM_005666.4
Organism	Homo sapiens(human)
Definition	Homo sapiens complement factor H related 2 (CFHR2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005666.4

ORF Insert Sequence:

ATGTGGCTCC TGGTCAGTGT AATTCTAATC TCACGGATAT CCTCTGTTGG GGGAGAAGCA 
ATGTTCTGTG ATTTTCCAAA AATAAACCAT GGAATTCTAT ATGATGAAGA AAAATATAAG 
CCATTTTCCC AAGTTCCTAC AGGGGAAGTT TTCTATTACT CCTGTGAATA TAATTTTGTG 
TCTCCTTCAA AATCCTTTTG GACTCGCATA ACGTGCGCAG AAGAAGGATG GTCACCAACA 
CCAAAGTGTC TCAGACTGTG TTTCTTTCCT TTTGTGGAAA ATGGTCATTC TGAATCTTCA 
GGACAAACAC ATCTGGAAGG TGATACTGTA CAAATTATTT GCAACACAGG ATACAGACTT 
CAAAACAATG AGAACAACAT TTCATGTGTA GAACGGGGCT GGTCCACTCC TCCCAAATGC 
AGGTCCACTA TTTCTGCAGA AAAATGTGGG CCCCCTCCAC CTATTGACAA TGGAGACATT 
ACTTCATTCC TGTTGTCAGT ATATGCTCCA GGTTCATCAG TTGAGTACCA GTGCCAGAAC 
TTGTATCAAC TTGAGGGTAA CAATCAAATA ACATGTAGAA ACGGACAATG GTCAGAACCA 
CCAAAATGCT TAGATCCATG TGTAATATCA CAAGAAATTA TGGAAAAATA TAACATAAAA 
TTAAAGTGGA CAAACCAACA AAAGCTTTAT TCAAGAACAG GTGACATAGT TGAATTTGTT 
TGTAAATCTG GATATCATCC AACAAAATCT CATTCATTTC GAGCAATGTG TCAGAATGGG 
AAACTGGTAT ATCCCAGTTG TGAAGAAAAA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CFHR2 ( XM_011509459.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011507761.1 Homo sapiens complement factor H related 2 (CFHR2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu58203
Clone ID Related Accession (Same CDS sequence)	XM_011509459.2
Accession Version	XM_011509459.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 753bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	complement factor H-related protein 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011509459.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTCTGTG ATTTTCCAAA AATAAACCAT GGAATTCTAT ATGATGAAGA AAAATATAAG 
CCATTTTCCC AAGTTCCTAC AGGGGAAGTT TTCTATTACT CCTGTGAATA TAATTTTGTG 
TCTCCTTCAA AATCCTTTTG GACTCGCATA ACGTGCGCAG AAGAAGGATG GTCACCAACA 
CCAAAGTGTC TCAGACTGTG TTTCTTTCCT TTTGTGGAAA ATGGTCATTC TGAATCTTCA 
GGACAAACAC ATCTGGAAGG TGATACTGTA CAAATTATTT GCAACACAGG ATACAGACTT 
CAAAACAATG AGAACAACAT TTCATGTGTA GAACGGGGCT GGTCCACTCC TCCCAAATGC 
AGGTCCACTA TTTCTGCAGA AAAATGTGGG CCCCCTCCAC CTATTGACAA TGGAGACATT 
ACTTCATTCC TGTTGTCAGT ATATGCTCCA GGTTCATCAG TTGAGTACCA GTGCCAGAAC 
TTGTATCAAC TTGAGGGTAA CAATCAAATA ACATGTAGAA ACGGACAATG GTCAGAACCA 
CCAAAATGCT TAGATCCATG TGTAATATCA CAAGAAATTA TGGAAAAATA TAACATAAAA 
TTAAAGTGGA CAAACCAACA AAAGCTTTAT TCAAGAACAG GTGACATAGT TGAATTTGTT 
TGTAAATCTG GATATCATCC AACAAAATCT CATTCATTTC GAGCAATGTG TCAGAATGGG 
AAACTGGTAT ATCCCAGTTG TGAAGAAAAA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011507761.1
CDS	208..960
Translation	MFCDFPKINHGILYDEEKYKPFSQVPTGEVFYYSCEYNFVSPSKSFWTRITCAEEGWSPTPKCLRLCFFPFVENGHSESSGQTHLEGDTVQIICNTGYRLQNNENNISCVERGWSTPPKCRSTISAEKCGPPPPIDNGDITSFLLSVYAPGSSVEYQCQNLYQLEGNNQITCRNGQWSEPPKCLDPCVISQEIMEKYNIKLKWTNQQKLYSRTGDIVEFVCKSGYHPTKSHSFRAMCQNGKLVYPSCEEK

Target ORF information:

RefSeq Version	XM_011509459.2
Organism	Homo sapiens(human)
Definition	Homo sapiens complement factor H related 2 (CFHR2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011509459.2

ORF Insert Sequence:

ATGTTCTGTG ATTTTCCAAA AATAAACCAT GGAATTCTAT ATGATGAAGA AAAATATAAG 
CCATTTTCCC AAGTTCCTAC AGGGGAAGTT TTCTATTACT CCTGTGAATA TAATTTTGTG 
TCTCCTTCAA AATCCTTTTG GACTCGCATA ACGTGCGCAG AAGAAGGATG GTCACCAACA 
CCAAAGTGTC TCAGACTGTG TTTCTTTCCT TTTGTGGAAA ATGGTCATTC TGAATCTTCA 
GGACAAACAC ATCTGGAAGG TGATACTGTA CAAATTATTT GCAACACAGG ATACAGACTT 
CAAAACAATG AGAACAACAT TTCATGTGTA GAACGGGGCT GGTCCACTCC TCCCAAATGC 
AGGTCCACTA TTTCTGCAGA AAAATGTGGG CCCCCTCCAC CTATTGACAA TGGAGACATT 
ACTTCATTCC TGTTGTCAGT ATATGCTCCA GGTTCATCAG TTGAGTACCA GTGCCAGAAC 
TTGTATCAAC TTGAGGGTAA CAATCAAATA ACATGTAGAA ACGGACAATG GTCAGAACCA 
CCAAAATGCT TAGATCCATG TGTAATATCA CAAGAAATTA TGGAAAAATA TAACATAAAA 
TTAAAGTGGA CAAACCAACA AAAGCTTTAT TCAAGAACAG GTGACATAGT TGAATTTGTT 
TGTAAATCTG GATATCATCC AACAAAATCT CATTCATTTC GAGCAATGTG TCAGAATGGG 
AAACTGGTAT ATCCCAGTTG TGAAGAAAAA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CFHR2 ( NM_001312672.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001299601.1 Homo sapiens complement factor H related 2 (CFHR2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu58201
Clone ID Related Accession (Same CDS sequence)	NM_001312672.1
Accession Version	NM_001312672.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 441bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Homo sapiens(human)
Product	complement factor H-related protein 2 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG563114.1, BC022283.1 and X64877.1. On Aug 14, 2015 this sequence version replaced XM_011509461.1. Transcript Variant: This variant (2) lacks two consecutive exons, but maintains the reading frame compared to variant 1. The resulting shorter isoform (2) is missing an internal protein segment compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BG566607.1, CB122245.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145122, SAMEA2155590 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTGGCTCC TGGTCAGTGT AATTCTAATC TCACGGATAT CCTCTGTTGG GGGAGAAGTT 
TCTGCAGAAA AATGTGGGCC CCCTCCACCT ATTGACAATG GAGACATTAC TTCATTCCTG 
TTGTCAGTAT ATGCTCCAGG TTCATCAGTT GAGTACCAGT GCCAGAACTT GTATCAACTT 
GAGGGTAACA ATCAAATAAC ATGTAGAAAC GGACAATGGT CAGAACCACC AAAATGCTTA 
GATCCATGTG TAATATCACA AGAAATTATG GAAAAATATA ACATAAAATT AAAGTGGACA 
AACCAACAAA AGCTTTATTC AAGAACAGGT GACATAGTTG AATTTGTTTG TAAATCTGGA 
TATCATCCAA CAAAATCTCA TTCATTTCGA GCAATGTGTC AGAATGGGAA ACTGGTATAT 
CCCAGTTGTG AAGAAAAATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001299601.1
CDS	114..554
Translation	MWLLVSVILISRISSVGGEVSAEKCGPPPPIDNGDITSFLLSVYAPGSSVEYQCQNLYQLEGNNQITCRNGQWSEPPKCLDPCVISQEIMEKYNIKLKWTNQQKLYSRTGDIVEFVCKSGYHPTKSHSFRAMCQNGKLVYPSCEEK

Target ORF information:

RefSeq Version	NM_001312672.1
Organism	Homo sapiens(human)
Definition	Homo sapiens complement factor H related 2 (CFHR2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001312672.1

ORF Insert Sequence:

ATGTGGCTCC TGGTCAGTGT AATTCTAATC TCACGGATAT CCTCTGTTGG GGGAGAAGTT 
TCTGCAGAAA AATGTGGGCC CCCTCCACCT ATTGACAATG GAGACATTAC TTCATTCCTG 
TTGTCAGTAT ATGCTCCAGG TTCATCAGTT GAGTACCAGT GCCAGAACTT GTATCAACTT 
GAGGGTAACA ATCAAATAAC ATGTAGAAAC GGACAATGGT CAGAACCACC AAAATGCTTA 
GATCCATGTG TAATATCACA AGAAATTATG GAAAAATATA ACATAAAATT AAAGTGGACA 
AACCAACAAA AGCTTTATTC AAGAACAGGT GACATAGTTG AATTTGTTTG TAAATCTGGA 
TATCATCCAA CAAAATCTCA TTCATTTCGA GCAATGTGTC AGAATGGGAA ACTGGTATAT 
CCCAGTTGTG AAGAAAAATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CFHR2 ( XM_005245113.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005245170.1 Homo sapiens complement factor H related 2 (CFHR2), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu34329
Clone ID Related Accession (Same CDS sequence)	XM_005245113.3
Accession Version	XM_005245113.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 618bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	complement factor H-related protein 2 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005245113.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGGCTCC TGGTCAGTGT AATTCTAATC TCACGGATAT CCTCTGTTGG GGGAGAAGGA 
CTGTGTTTCT TTCCTTTTGT GGAAAATGGT CATTCTGAAT CTTCAGGACA AACACATCTG 
GAAGGTGATA CTGTACAAAT TATTTGCAAC ACAGGATACA GACTTCAAAA CAATGAGAAC 
AACATTTCAT GTGTAGAACG GGGCTGGTCC ACTCCTCCCA AATGCAGGTC CACTATTTCT 
GCAGAAAAAT GTGGGCCCCC TCCACCTATT GACAATGGAG ACATTACTTC ATTCCTGTTG 
TCAGTATATG CTCCAGGTTC ATCAGTTGAG TACCAGTGCC AGAACTTGTA TCAACTTGAG 
GGTAACAATC AAATAACATG TAGAAACGGA CAATGGTCAG AACCACCAAA ATGCTTAGAT 
CCATGTGTAA TATCACAAGA AATTATGGAA AAATATAACA TAAAATTAAA GTGGACAAAC 
CAACAAAAGC TTTATTCAAG AACAGGTGAC ATAGTTGAAT TTGTTTGTAA ATCTGGATAT 
CATCCAACAA AATCTCATTC ATTTCGAGCA ATGTGTCAGA ATGGGAAACT GGTATATCCC 
AGTTGTGAAG AAAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005245170.1
CDS	128..745
Translation	MWLLVSVILISRISSVGGEGLCFFPFVENGHSESSGQTHLEGDTVQIICNTGYRLQNNENNISCVERGWSTPPKCRSTISAEKCGPPPPIDNGDITSFLLSVYAPGSSVEYQCQNLYQLEGNNQITCRNGQWSEPPKCLDPCVISQEIMEKYNIKLKWTNQQKLYSRTGDIVEFVCKSGYHPTKSHSFRAMCQNGKLVYPSCEEK

Target ORF information:

RefSeq Version	XM_005245113.3
Organism	Homo sapiens(human)
Definition	Homo sapiens complement factor H related 2 (CFHR2), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005245113.3

ORF Insert Sequence:

ATGTGGCTCC TGGTCAGTGT AATTCTAATC TCACGGATAT CCTCTGTTGG GGGAGAAGGA 
CTGTGTTTCT TTCCTTTTGT GGAAAATGGT CATTCTGAAT CTTCAGGACA AACACATCTG 
GAAGGTGATA CTGTACAAAT TATTTGCAAC ACAGGATACA GACTTCAAAA CAATGAGAAC 
AACATTTCAT GTGTAGAACG GGGCTGGTCC ACTCCTCCCA AATGCAGGTC CACTATTTCT 
GCAGAAAAAT GTGGGCCCCC TCCACCTATT GACAATGGAG ACATTACTTC ATTCCTGTTG 
TCAGTATATG CTCCAGGTTC ATCAGTTGAG TACCAGTGCC AGAACTTGTA TCAACTTGAG 
GGTAACAATC AAATAACATG TAGAAACGGA CAATGGTCAG AACCACCAAA ATGCTTAGAT 
CCATGTGTAA TATCACAAGA AATTATGGAA AAATATAACA TAAAATTAAA GTGGACAAAC 
CAACAAAAGC TTTATTCAAG AACAGGTGAC ATAGTTGAAT TTGTTTGTAA ATCTGGATAT 
CATCCAACAA AATCTCATTC ATTTCGAGCA ATGTGTCAGA ATGGGAAACT GGTATATCCC 
AGTTGTGAAG AAAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CFHR2 ( XM_011509458.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011507760.1 Homo sapiens complement factor H related 2 (CFHR2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu58202
Clone ID Related Accession (Same CDS sequence)	XM_011509458.2
Accession Version	XM_011509458.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 801bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	complement factor H-related protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011509458.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGGCTCC TGGTCAGTGT AATTCTAATC TCACGGATAT CCTCTGTTGG GGGAGAAGCA 
ATGTTCTGTG ATTTTCCAAA AATAAACCAT GGAATTCTAT ATGATGAAGA AAAATATAAG 
CCATTTTCCC AAGTTCCTAC AGGGGAAGTT TTCTATTACT CCTGTGAATA TAATTTTGTG 
TCTCCTTCAA AATCCTTTTG GACTCGCATA ACGTGCGCAG AAGAAGGATG GTCACCAACA 
CCAAAGTGTC TCAGACTGTG TTTCTTTCCT TTTGTGGAAA ATGGTCATTC TGAATCTTCA 
GGACAAACAC ATCTGGAAGG TGATACTGTA CAAATTATTT GCAACACAGG ATACAGACTT 
CAAAACAATG AGAACAACAT TTCATGTGTA GAACGGGGCT GGTCCACTCC TCCCAAATTT 
TCTGCAGAAA AATGTGGGCC CCCTCCACCT ATTGACAATG GAGACATTAC TTCATTCCTG 
TTGTCAGTAT ATGCTCCAGG TTCATCAGTT GAGTACCAGT GCCAGAACTT GTATCAACTT 
GAGGGTAACA ATCAAATAAC ATGTAGAAAC GGACAATGGT CAGAACCACC AAAATGCTTA 
GATCCATGTG TAATATCACA AGAAATTATG GAAAAATATA ACATAAAATT AAAGTGGACA 
AACCAACAAA AGCTTTATTC AAGAACAGGT GACATAGTTG AATTTGTTTG TAAATCTGGA 
TATCATCCAA CAAAATCTCA TTCATTTCGA GCAATGTGTC AGAATGGGAA ACTGGTATAT 
CCCAGTTGTG AAGAAAAATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011507760.1
CDS	98..898
Translation	MWLLVSVILISRISSVGGEAMFCDFPKINHGILYDEEKYKPFSQVPTGEVFYYSCEYNFVSPSKSFWTRITCAEEGWSPTPKCLRLCFFPFVENGHSESSGQTHLEGDTVQIICNTGYRLQNNENNISCVERGWSTPPKFSAEKCGPPPPIDNGDITSFLLSVYAPGSSVEYQCQNLYQLEGNNQITCRNGQWSEPPKCLDPCVISQEIMEKYNIKLKWTNQQKLYSRTGDIVEFVCKSGYHPTKSHSFRAMCQNGKLVYPSCEEK

Target ORF information:

RefSeq Version	XM_011509458.2
Organism	Homo sapiens(human)
Definition	Homo sapiens complement factor H related 2 (CFHR2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011509458.2

ORF Insert Sequence:

ATGTGGCTCC TGGTCAGTGT AATTCTAATC TCACGGATAT CCTCTGTTGG GGGAGAAGCA 
ATGTTCTGTG ATTTTCCAAA AATAAACCAT GGAATTCTAT ATGATGAAGA AAAATATAAG 
CCATTTTCCC AAGTTCCTAC AGGGGAAGTT TTCTATTACT CCTGTGAATA TAATTTTGTG 
TCTCCTTCAA AATCCTTTTG GACTCGCATA ACGTGCGCAG AAGAAGGATG GTCACCAACA 
CCAAAGTGTC TCAGACTGTG TTTCTTTCCT TTTGTGGAAA ATGGTCATTC TGAATCTTCA 
GGACAAACAC ATCTGGAAGG TGATACTGTA CAAATTATTT GCAACACAGG ATACAGACTT 
CAAAACAATG AGAACAACAT TTCATGTGTA GAACGGGGCT GGTCCACTCC TCCCAAATTT 
TCTGCAGAAA AATGTGGGCC CCCTCCACCT ATTGACAATG GAGACATTAC TTCATTCCTG 
TTGTCAGTAT ATGCTCCAGG TTCATCAGTT GAGTACCAGT GCCAGAACTT GTATCAACTT 
GAGGGTAACA ATCAAATAAC ATGTAGAAAC GGACAATGGT CAGAACCACC AAAATGCTTA 
GATCCATGTG TAATATCACA AGAAATTATG GAAAAATATA ACATAAAATT AAAGTGGACA 
AACCAACAAA AGCTTTATTC AAGAACAGGT GACATAGTTG AATTTGTTTG TAAATCTGGA 
TATCATCCAA CAAAATCTCA TTCATTTCGA GCAATGTGTC AGAATGGGAA ACTGGTATAT 
CCCAGTTGTG AAGAAAAATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CFHR2 ( XM_011509460.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011507762.1 Homo sapiens complement factor H related 2 (CFHR2), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu58204
Clone ID Related Accession (Same CDS sequence)	XM_011509460.2
Accession Version	XM_011509460.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 606bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	complement factor H-related protein 2 isoform X5
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011509460.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGGCTCC TGGTCAGTGT AATTCTAATC TCACGGATAT CCTCTGTTGG GGGAGAAGGA 
CTGTGTTTCT TTCCTTTTGT GGAAAATGGT CATTCTGAAT CTTCAGGACA AACACATCTG 
GAAGGTGATA CTGTACAAAT TATTTGCAAC ACAGGATACA GACTTCAAAA CAATGAGAAC 
AACATTTCAT GTGTAGAACG GGGCTGGTCC ACTCCTCCCA AATTTTCTGC AGAAAAATGT 
GGGCCCCCTC CACCTATTGA CAATGGAGAC ATTACTTCAT TCCTGTTGTC AGTATATGCT 
CCAGGTTCAT CAGTTGAGTA CCAGTGCCAG AACTTGTATC AACTTGAGGG TAACAATCAA 
ATAACATGTA GAAACGGACA ATGGTCAGAA CCACCAAAAT GCTTAGATCC ATGTGTAATA 
TCACAAGAAA TTATGGAAAA ATATAACATA AAATTAAAGT GGACAAACCA ACAAAAGCTT 
TATTCAAGAA CAGGTGACAT AGTTGAATTT GTTTGTAAAT CTGGATATCA TCCAACAAAA 
TCTCATTCAT TTCGAGCAAT GTGTCAGAAT GGGAAACTGG TATATCCCAG TTGTGAAGAA 
AAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011507762.1
CDS	130..735
Translation	MWLLVSVILISRISSVGGEGLCFFPFVENGHSESSGQTHLEGDTVQIICNTGYRLQNNENNISCVERGWSTPPKFSAEKCGPPPPIDNGDITSFLLSVYAPGSSVEYQCQNLYQLEGNNQITCRNGQWSEPPKCLDPCVISQEIMEKYNIKLKWTNQQKLYSRTGDIVEFVCKSGYHPTKSHSFRAMCQNGKLVYPSCEEK

Target ORF information:

RefSeq Version	XM_011509460.2
Organism	Homo sapiens(human)
Definition	Homo sapiens complement factor H related 2 (CFHR2), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011509460.2

ORF Insert Sequence:

ATGTGGCTCC TGGTCAGTGT AATTCTAATC TCACGGATAT CCTCTGTTGG GGGAGAAGGA 
CTGTGTTTCT TTCCTTTTGT GGAAAATGGT CATTCTGAAT CTTCAGGACA AACACATCTG 
GAAGGTGATA CTGTACAAAT TATTTGCAAC ACAGGATACA GACTTCAAAA CAATGAGAAC 
AACATTTCAT GTGTAGAACG GGGCTGGTCC ACTCCTCCCA AATTTTCTGC AGAAAAATGT 
GGGCCCCCTC CACCTATTGA CAATGGAGAC ATTACTTCAT TCCTGTTGTC AGTATATGCT 
CCAGGTTCAT CAGTTGAGTA CCAGTGCCAG AACTTGTATC AACTTGAGGG TAACAATCAA 
ATAACATGTA GAAACGGACA ATGGTCAGAA CCACCAAAAT GCTTAGATCC ATGTGTAATA 
TCACAAGAAA TTATGGAAAA ATATAACATA AAATTAAAGT GGACAAACCA ACAAAAGCTT 
TATTCAAGAA CAGGTGACAT AGTTGAATTT GTTTGTAAAT CTGGATATCA TCCAACAAAA 
TCTCATTCAT TTCGAGCAAT GTGTCAGAAT GGGAAACTGG TATATCCCAG TTGTGAAGAA 
AAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CFHR2 ( XM_017001109.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016856598.1 Homo sapiens complement factor H related 2 (CFHR2), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu87294
Clone ID Related Accession (Same CDS sequence)	XM_017001109.1
Accession Version	XM_017001109.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 636bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	complement factor H-related protein 2 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGGCTCC TGGTCAGTGT AATTCTAATC TCACGGATAT CCTCTGTTGG GGGAGAAGCA 
ATGTTCTGTG ATTTTCCAAA AATAAACCAT GGAATTCTAT ATGATGAAGA AAAATATAAG 
CCATTTTCCC AAGTTCCTAC AGGGGAAGTT TTCTATTACT CCTGTGAATA TAATTTTGTG 
TCTCCTTCAA AATCCTTTTG GACTCGCATA ACGTGCGCAG AAGAAGGATG GTCACCAACA 
CCAAAGTGTC TCATTTCTGC AGAAAAATGT GGGCCCCCTC CACCTATTGA CAATGGAGAC 
ATTACTTCAT TCCTGTTGTC AGTATATGCT CCAGGTTCAT CAGTTGAGTA CCAGTGCCAG 
AACTTGTATC AACTTGAGGG TAACAATCAA ATAACATGTA GAAACGGACA ATGGTCAGAA 
CCACCAAAAT GCTTAGATCC ATGTGTAATA TCACAAGAAA TTATGGAAAA ATATAACATA 
AAATTAAAGT GGACAAACCA ACAAAAGCTT TATTCAAGAA CAGGTGACAT AGTTGAATTT 
GTTTGTAAAT CTGGATATCA TCCAACAAAA TCTCATTCAT TTCGAGCAAT GTGTCAGAAT 
GGGAAACTGG TATATCCCAG TTGTGAAGAA AAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016856598.1
CDS	98..733
Translation	MWLLVSVILISRISSVGGEAMFCDFPKINHGILYDEEKYKPFSQVPTGEVFYYSCEYNFVSPSKSFWTRITCAEEGWSPTPKCLISAEKCGPPPPIDNGDITSFLLSVYAPGSSVEYQCQNLYQLEGNNQITCRNGQWSEPPKCLDPCVISQEIMEKYNIKLKWTNQQKLYSRTGDIVEFVCKSGYHPTKSHSFRAMCQNGKLVYPSCEEK

Target ORF information:

RefSeq Version	XM_017001109.1
Organism	Homo sapiens(human)
Definition	Homo sapiens complement factor H related 2 (CFHR2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017001109.1

ORF Insert Sequence:

ATGTGGCTCC TGGTCAGTGT AATTCTAATC TCACGGATAT CCTCTGTTGG GGGAGAAGCA 
ATGTTCTGTG ATTTTCCAAA AATAAACCAT GGAATTCTAT ATGATGAAGA AAAATATAAG 
CCATTTTCCC AAGTTCCTAC AGGGGAAGTT TTCTATTACT CCTGTGAATA TAATTTTGTG 
TCTCCTTCAA AATCCTTTTG GACTCGCATA ACGTGCGCAG AAGAAGGATG GTCACCAACA 
CCAAAGTGTC TCATTTCTGC AGAAAAATGT GGGCCCCCTC CACCTATTGA CAATGGAGAC 
ATTACTTCAT TCCTGTTGTC AGTATATGCT CCAGGTTCAT CAGTTGAGTA CCAGTGCCAG 
AACTTGTATC AACTTGAGGG TAACAATCAA ATAACATGTA GAAACGGACA ATGGTCAGAA 
CCACCAAAAT GCTTAGATCC ATGTGTAATA TCACAAGAAA TTATGGAAAA ATATAACATA 
AAATTAAAGT GGACAAACCA ACAAAAGCTT TATTCAAGAA CAGGTGACAT AGTTGAATTT 
GTTTGTAAAT CTGGATATCA TCCAACAAAA TCTCATTCAT TTCGAGCAAT GTGTCAGAAT 
GGGAAACTGG TATATCCCAG TTGTGAAGAA AAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

CFHR2-rs2986127 as a genetic protective marker for acute anterior uveitis in Chinese patients.
The journal of gene medicine18(8)193-8(2016 Aug)
Huang XF,Wang Y,Li FF,Lin D,Dai ML,Wang QF,Jin ZB

Sequence and Expression of Complement Factor H Gene Cluster Variants and Their Roles in Age-Related Macular Degeneration Risk.
Investigative ophthalmology & visual science57(6)2763-9(2016 05)
Hughes AE,Bridgett S,Meng W,Li M,Curcio CA,Stambolian D,Bradley DT

Factor H-related proteins determine complement-activating surfaces.
Trends in immunology36(6)374-84(2015 Jun)
J?zsi M,Tortajada A,Uzonyi B,Goicoechea de Jorge E,Rodr?guez de C?rdoba S

Atypical haemolytic-uraemic syndrome due to heterozygous mutations of CFH/CFHR1-3 and complement factor H 479.
Blood transfusion = Trasfusione del sangue12(1)111-3(2014 Jan)
Chaudhary P,Hepgur M,Sarkissian S,Smith RJ,Weitz IC

Complement factor H-related hybrid protein deregulates complement in dense deposit disease.
The Journal of clinical investigation124(1)145-55(2014 Jan)
Chen Q,Wiesener M,Eberhardt HU,Hartmann A,Uzonyi B,Kirschfink M,Amann K,Buettner M,Goodship T,Hugo C,Skerka C,Zipfel PF

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CFHR2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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FAX

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